keyword
https://read.qxmd.com/read/38454392/pneumococcal-vaccine-uptake-among-high-risk-adults-and-children-in-italy-results-from-the-obvious-project-survey
#21
JOURNAL ARTICLE
Zeno Di Valerio, Giusy La Fauci, Francesca Scognamiglio, Aurelia Salussolia, Marco Montalti, Angelo Capodici, Maria Pia Fantini, Anna Odone, Claudio Costantino, Giorgia Soldà, Heidi J Larson, Julie Leask, Jacopo Lenzi, Davide Gori
BACKGROUND: Streptococcus pneumoniae infections, including Invasive Pneumococcal Diseases (IPDs), pose a substantial public health challenge, causing significant morbidity and mortality, especially among children and older adults. Vaccination campaigns have played a vital role in reducing pneumococcal-related deaths. However, obstacles related to accessibility and awareness might impede optimal vaccine adoption. This study aims to provide comprehensive data on pneumococcal vaccine coverage and attitudes within at-risk groups in Italy, with the goal of informing public health strategies and addressing vaccination barriers...
March 7, 2024: BMC Public Health
https://read.qxmd.com/read/38449518/antibiotic-susceptibility-patterns-at-the-m%C3%A3-decins-sans-fronti%C3%A3-res-msf-acute-trauma-hospital-in-aden-yemen-a-retrospective-study-from-january-2018-to-june-2021
#22
JOURNAL ARTICLE
Hussein Almehdar, Nagwan Yousef, Wilma van den Boogaard, Amna Haider, Rupa Kanapathipillai, Emad Al-Hodiani, Evgenia Zelikova, Waddah G Moh'd, Justine Michel, Rami Malaeb
BACKGROUND: Antimicrobial resistance (AMR) is an urgent global health concern, especially in countries facing instability or conflicts, with compromised healthcare systems. Médecins Sans Frontières (MSF) established an acute trauma hospital in Aden, Yemen, treating mainly war-wounded civilians, and implemented an antimicrobial stewardship (AMS) programme. This study aimed to describe clinical characteristics and identify antibiotic susceptibility patterns representative of patients treated with antibiotics...
April 2024: JAC-antimicrobial resistance
https://read.qxmd.com/read/38449053/epidemiologic-analysis-of-antimicrobial-resistance-in-hospital-departments-in-china-from-2022-to-2023
#23
JOURNAL ARTICLE
Hui-Jun Bai, Qing-Feng Geng, Fang Jin, Yong-Li Yang
Bacterial drug resistance monitoring in hospitals is a crucial aspect of healthcare management and a growing concern worldwide. In this study, we analysed the bacterial drug resistance surveillance in our hospital from 2022 Q1 to 2023 Q2. The main sampling sources were respiratory, blood, and urine-based, and the main clinical infections were respiratory and genitourinary in nature. Specimens were inoculated and cultured; bacterial strains were isolated using a VITEK® 2 Compact 60-card automatic microorganism identifier (bioMerieux, Paris, France) and their matching identification cards were identified, and manual tests were supplemented for strain identification...
March 6, 2024: Journal of Health, Population, and Nutrition
https://read.qxmd.com/read/38449045/automated-surveillance-of-non-ventilator-associated-hospital-acquired-pneumonia-nvhap-a-systematic-literature-review
#24
JOURNAL ARTICLE
Aline Wolfensberger, Alexandra U Scherrer, Hugo Sax
BACKGROUND: Hospital-acquired pneumonia (HAP) and its specific subset, non-ventilator hospital-acquired pneumonia (nvHAP) are significant contributors to patient morbidity and mortality. Automated surveillance systems for these healthcare-associated infections have emerged as a potentially beneficial replacement for manual surveillance. This systematic review aims to synthesise the existing literature on the characteristics and performance of automated nvHAP and HAP surveillance systems...
March 6, 2024: Antimicrobial Resistance and Infection Control
https://read.qxmd.com/read/38447803/how-long-do-nosocomial-pathogens-persist-on-inanimate-surfaces-a-scoping-review
#25
REVIEW
Lucy Porter, Ola Sultan, Brett G Mitchell, Adam Jenney, Martin Kiernan, David J Brewster, Philip L Russo
Healthcare hygiene plays a crucial role in the prevention of healthcare associated infections. Patients admitted to a room where the previous occupant had a multidrug resistant bacterial infection are at an increased risk of colonisation and infection with the same organism. A 2006 systematic review by Kramer et al found that certain pathogens can survive for months on dry surfaces. The aim of this review is to update Kramer et al's previous review and provide contemporary data on the survival of pathogens relevant to the healthcare environment...
March 4, 2024: Journal of Hospital Infection
https://read.qxmd.com/read/38446208/acute-kidney-injury-requiring-dialysis-in-children-a-multicentric-emerging-country-perspective
#26
JOURNAL ARTICLE
Thais Lira Cleto-Yamane, Conrado Lysandro R Gomes, Paulo Cesar Koch-Nogueira, José Hermógenes Rocco Suassuna
BACKGROUND: Acute kidney injury (AKI) is a life-threatening condition, especially in extreme age groups and when kidney replacement therapy (KRT) is necessary. Studies worldwide report mortality rates of 10-63% in pediatric patients undergoing KRT. METHODS: Over 13 years, this multicenter study analyzed data from 693 patients with AKI, all receiving KRT, across 74 hospitals and medical facilities in Rio de Janeiro, Brazil. RESULTS: The majority were male (59...
March 6, 2024: Pediatric Nephrology
https://read.qxmd.com/read/38446073/carbapenemase-producing-enterobacterales-strains-causing-infections-in-companion-animals-portugal
#27
JOURNAL ARTICLE
Joana Moreira da Silva, Juliana Menezes, Laura Fernandes, Sofia Santos Costa, Andreia Amaral, Constança Pomba
UNLABELLED: An increase in Klebsiella pneumoniae carbapenem-resistant human nosocomial strains is occurring in Europe, namely with the bla OXA-48-like and bla KPC-like genes. We determined the prevalence of carbapenemase-producing Enterobacterales clinical strains in companion animals in Portugal and characterized their mobile genetic elements. Susceptibility data of a consecutive collection of 977 Enterobacterales clinical strains from a Portuguese private veterinary diagnostic laboratory were evaluated (January-December 2020)...
March 6, 2024: Microbiology Spectrum
https://read.qxmd.com/read/38445383/antibacterial-agents-active-against-gram-negative-bacilli-in-phase-i-ii-or-iii-clinical-trials
#28
REVIEW
David L Paterson
INTRODUCTION: Antimicrobial resistance is a major threat to modern healthcare, and it is often regarded that the antibiotic pipeline is 'dry.' AREAS COVERED: Antimicrobial agents active against Gram negative bacilli in Phase I, II, or III clinical trials were reviewed. EXPERT OPINION: Nearly 50 antimicrobial agents (28 small molecules and 21 non-traditional antimicrobial agents) active against Gram-negative bacilli are currently in clinical trials...
March 6, 2024: Expert Opinion on Investigational Drugs
https://read.qxmd.com/read/38444439/a-study-on-the-factors-influencing-the-intention-to-receive-booster-shots-of-the-covid-19-vaccine-in-china-based-on-the-information-frame-effect
#29
JOURNAL ARTICLE
Qizhen Zhu, Yunyun Gao, Qingyuan Hu, DeHua Hu, Xusheng Wu
INTRODUCTION: In the response to and prevention and control of the Novel coronavirus pneumonia, the COVID-19 vaccine does not provide lifelong immunity, and it is therefore important to increase the rate of booster shots of the COVID-19 vaccine. In the field of information health science, research has found that information frames have an impact in changing individual attitudes and health behaviors. OBJECTIVE: This study focuses on the effects of different influencing factors on the public's willingness to receive the booster shots of the COVID-19 vaccine under two information frameworks...
2024: Frontiers in Public Health
https://read.qxmd.com/read/38442129/antibacterial-activity-and-phytochemical-screening-of-traditional-medicinal-plants-most-preferred-for-treating-infectious-diseases-in-habru-district-north-wollo-zone-amhara-region-ethiopia
#30
JOURNAL ARTICLE
Mulugeta Alemu, Ermias Lulekal, Zemede Asfaw, Bikila Warkineh, Asfaw Debella, Abiy Abebe, Sileshi Degu, Eyob Debebe
Ethiopia's healthcare system relies on traditional medicinal practices that use medicinal plants to treat human and livestock ailments. However, the lack of empirical validation regarding the efficacy of these treatments against specific infectious diseases necessitates rigorous scientific investigations. The objective of this study was to investigate the antibacterial activity and phytochemical screening on five selected medicinal plant species, namely Solanum somalense Franchet., Verbascum sinaiticum Benth...
2024: PloS One
https://read.qxmd.com/read/38436606/candent-issues-in-pneumonia-reflections-from-the-fifth-annual-meeting-of-spanish-experts-2023
#31
REVIEW
C M Rodríguez-Leal, C González-Corralejo, F J Candel, M Salavert
Pneumonia is a multifaceted illness with a wide range of clinical manifestations, degree of severity and multiple potential causing microorganisms. Despite the intensive research of recent decades, community-acquired pneumonia remains the third-highest cause of mortality in developed countries and the first due to infections; and hospital-acquired pneumonia is the main cause of death from nosocomial infection in critically ill patients. Guidelines for management of this disease are available world wide, but there are questions which generate controversy, and the latest advances make it difficult to stay them up to date...
March 4, 2024: Revista Española de Quimioterapia: Publicación Oficial de la Sociedad Española de Quimioterapia
https://read.qxmd.com/read/38434551/extended-spectrum-%C3%AE-lactamase-producing-escherichia-coli-and-klebsiella-pneumoniae-risk-factors-and-economic-burden-among-patients-with-bloodstream-infections
#32
JOURNAL ARTICLE
Jiakang Chen, Kasim Allel, Chuyue Zhuo, Wenwei Luo, Nanhao He, Xu Yang, Yingyi Guo, Jiong Wang, Likang Yao, Jiahui Li, Yexin Lin, Ruiyang Tu, Laith Yakob, Chao Zhuo
INTRODUCTION: Although Extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae (ESBL-EK) significantly contribute to bloodstream infections, their economic repercussions remain largely unquantified. DATA SOURCE AND METHODS: We performed a retrospective analysis of inpatients diagnosed with Escherichia coli or Klebsiella pneumoniae bacteremia in a tertiary hospital from January 2020 to December 2022 in Guangzhou, China. We employed the chi-square test to examine ESBL risk factors and utilized propensity score matching (PSM) to negate baseline confounding factors, assessing economic burden through disability-adjusted life years (DALYs), hospital costs and productivity losses...
2024: Risk Management and Healthcare Policy
https://read.qxmd.com/read/38432476/ventilator-associated-events-in-adults-a-secondary-analysis-assessing-the-impact-of-monitoring-ventilator-settings-on-outcomes
#33
JOURNAL ARTICLE
Sergio Ramírez-Estrada, Yolanda Peña-López, Marta Serrano-Megías, Jordi Rello
BACKGROUND: Ventilator-associated Events (VAE) is a tier implemented for surveillance by the CDC in the USA. Implementation usefulness for clinical decisions is unknown. METHODS: We conducted a secondary analysis from a prospective, multicentre, international study, to assess the impact on outcomes of using tiers with shorter follow-up (VAE24), lower oxygenation requirements (light-VAE) or both (lightVAE24). RESULTS: A cohort of 261 adults with 2706 ventilator-days were included...
March 1, 2024: Anaesthesia, Critical Care & Pain Medicine
https://read.qxmd.com/read/38431802/healthcare-associated-infections-after-neurosurgical-procedures-in-ukraine-a-multicentre-study-2020-2022
#34
JOURNAL ARTICLE
Aidyn G Salmanov, Dmytro V Shchehlov, Maryna Mamonova, Ihor M Bortnik, Nadiia B Chabanovych, Yaroslav E Kudelskyi, Daria Chekhunova
OBJECTIVE: Aim: To investigate the epidemiology, microbiology, and risk factors for healthcare-associated infections (HAIs) after a neurosurgical procedure in Ukraine. PATIENTS AND METHODS: Materials and Methods: Prospective multicentre surveillance was conducted from January 2020 to December 2022 in 10 regional hospitals of Ukraine. Definitions of HAIs were adapted from the Centers for Disease Control and Prevention's National Healthcare Safety Network. RESULTS: Results: Of 8,623 neurosurgical patients, 1,579 (18...
2024: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://read.qxmd.com/read/38430143/the-complications-of-corticosteroid-for-patients-with-community-acquired-pneumonia-a-systematic-review-and-meta-analysis
#35
JOURNAL ARTICLE
Donglan Wang, Yan Zhu
BACKGROUND: Many randomized controlled trials (RCTs) have reported the complications of corticosteroids for patients with community-acquired pneumonia with inconsistent results. An explicit systematic review and meta-analysis were conducted in this study to evaluate the complications of corticosteroids for patients with community-acquired pneumonia. METHODS: Using PubMed, Embase, the Global Index Medicus of the World Health Organization (WHO), the WHO clinical trial registry, and Clinicaltrials...
March 1, 2024: Alternative Therapies in Health and Medicine
https://read.qxmd.com/read/38429810/the-role-of-staphylococcus-aureus-quorum-sensing-in-cutaneous-and-systemic-infections
#36
REVIEW
Yuriko Yamazaki, Tomoka Ito, Masakazu Tamai, Seitaro Nakagawa, Yuumi Nakamura
BACKGROUND: Staphylococcus aureus is a leading cause of human bacterial infections worldwide. It is the most common causative agent of skin and soft tissue infections, and can also cause various other infections, including pneumonia, osteomyelitis, as well as life-threatening infections, such as sepsis and infective endocarditis. The pathogen can also asymptomatically colonize human skin, nasal cavity, and the intestine. S. aureus colonizes approximately 20-30% of human nostrils, being an opportunistic pathogen for subsequent infection...
March 1, 2024: Inflammation and Regeneration
https://read.qxmd.com/read/38429064/measuring-evidence-based-clinical-guideline-compliance-in-the-paediatric-intensive-care-unit
#37
JOURNAL ARTICLE
Rebecca E Hay, Dori-Ann Martin, Gary J Rutas, Shelina M Jamal, Simon J Parsons
BACKGROUND: Evidence-based clinical care guidelines improve medical treatment by reducing error, improving outcomes and possibly lowering healthcare costs. While some data exist on individual guideline compliance, no data exist on overall compliance to multiple nuanced guidelines in a paediatric intensive care setting. METHODS: Guideline compliance was observed and measured with a prospective cohort at a tertiary academic paediatric medical-surgical intensive care unit...
March 1, 2024: BMJ Open Quality
https://read.qxmd.com/read/38425611/evaluation-of-the-district-health-information-system-in-district-kotli-azad-jammu-and-kashmir-a-retrospective-analysis
#38
JOURNAL ARTICLE
Mohammad Saleem Khan, Khawaja Faizan Ejaz, Khan Adnan, Sohail Ahmed, Humayun Saleem, Sarosh Khan Jadoon, Amna Akbar, Sabahat Tasneem
BACKGROUND: It is essential to implement a high-quality electronic database for keeping important information. The District Health Information System (DHIS) is an active data-keeping system in Pakistan. This study aimed to evaluate the patients' data from the DHIS dashboard for the District Headquarters Hospital, Kotli, Azad Jammu and Kashmir (AJK). METHODOLOGY: The data was requested from the hospital administration at District Headquarters Hospital, Kotli, AJK, and the data was analyzed after permission was granted...
January 2024: Curēus
https://read.qxmd.com/read/38423305/hidden-threats-in-the-plastisphere-carbapenemase-producing-enterobacterales-colonizing-microplastics-in-river-water
#39
JOURNAL ARTICLE
Isabel Silva, Marta Tacão, Isabel Henriques
Carbapenem resistance poses a significant burden on healthcare systems worldwide. Microplastics (MPs) have emerged as potential contributors to antibiotic resistance spread in the environment. However, the link between MPs and carbapenem resistance remains unexplored. We investigated the prevalence of carbapenem-resistant bacteria colonizing MPs placed in a river. Three replicates of a mixture of polypropylene (PP), polyethylene (PE) and polyethylene terephthalate (PET) and of PET alone were placed both upstream and downstream a wastewater treatment plant (WWTP) discharge...
February 27, 2024: Science of the Total Environment
https://read.qxmd.com/read/38422884/adverse-outcomes-of-intrinsic-capacity-in-older-adults-a-scoping-review
#40
REVIEW
Yiyi Yang, Guifen Ma, Suhong Wei, Xiaoqin Wei, Bailing Yan, Yue Yuan, Yajing Chen, Jiangxia Qin, Yuxia Ma
Background and Purpose Intrinsic capacity (IC) has been shown to have the greatest impact on an individual's health status and health trajectory and can independently predict adverse outcomes such as mortality and care dependency in older adults. However, the current understanding of adverse outcomes associated with IC is incomplete. Methods A scoping review of the literature from PubMed, Web of Science (WOS), The Cochrane Library, CINAHL, and Embase databases was conducted from January 2015 to March 2023 to identify articles related to the adverse outcomes associated with IC in older adults...
May 2024: Archives of Gerontology and Geriatrics
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