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https://www.readbyqxmd.com/read/29217694/updated-birth-weight-centiles-for-england-and-wales
#1
Tom Norris, Sarah E Seaton, Brad N Manktelow, Philip N Baker, Jennifer J Kurinczuk, David Field, Elizabeth S Draper, Lucy K Smith
OBJECTIVES: Construct updated birth weight-for-gestational age centile charts for use in the UK and compare these to the currently used UK-WHO charts. DESIGN: Secondary analysis of national birth data. PARTICIPANTS: Centiles were constructed using 1 269 403 singleton births occurring in England and Wales in 2013-2014 as part of the MBRRACE-UK national perinatal surveillance programme. These were then validated using 642 737 singleton births occurring in England and Wales in 2015...
December 7, 2017: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/29216559/pregnancy-outcomes-and-ethanol-cook-stove-intervention-a-randomized-controlled-trial-in-ibadan-nigeria
#2
Donee A Alexander, Amanda Northcross, Theodore Karrison, Oludare Morhasson-Bello, Nathaniel Wilson, Omolola M Atalabi, Anindita Dutta, Damilola Adu, Tope Ibigbami, John Olamijulo, Dayo Adepoju, Oladosu Ojengbede, Christopher O Olopade
BACKGROUND: Household air pollution (HAP) exposure has been linked to adverse pregnancy outcomes. OBJECTIVES: A randomized controlled trial was undertaken in Ibadan, Nigeria to determine the impact of cooking with ethanol on pregnancy outcomes. METHODS: Three-hundred-twenty-four pregnant women were randomized to either the control (continued cooking using kerosene/firewood stove, n=162) or intervention group (received ethanol stove, n=162)...
December 4, 2017: Environment International
https://www.readbyqxmd.com/read/29208042/abnormal-placental-cord-insertion-and-adverse-pregnancy-outcomes-a-systematic-review-and-meta-analysis
#3
Khadijah Irfah Ismail, Ailish Hannigan, Keelin O'Donoghue, Amanda Cotter
BACKGROUND: Abnormal placental cord insertion (PCI) includes marginal cord insertion (MCI) and velamentous cord insertion (VCI). VCI has been shown to be associated with adverse pregnancy outcomes. This systematic review and meta-analysis aims to determine the association of abnormal PCI and adverse pregnancy outcomes. METHODS: Embase, Medline, CINAHL, Scopus, Web of Science, ClinicalTrials.gov, and Cochrane Databases were searched in December 2016 (from inception to December 2016)...
December 6, 2017: Systematic Reviews
https://www.readbyqxmd.com/read/29200473/effect-of-premature-rupture-of-membranes-on-induction-of-labor-a-historical-cohort-study
#4
Sven Kehl, Christel Weiss, Ulf Dammer, Friederike Baier, Florian Faschingbauer, Matthias W Beckmann, Marc Sütterlin, Jutta Pretscher
Objective: The aim of this study was to assess the influence of premature rupture of membranes (PROM) on the induction of labor. Material and Method: This historical cohort study analyzed 1861 inductions of labor at term using misoprostol which occurred between 2010 and 2015. Exclusion criteria included intrauterine fetal death, previous cesarean section, and fetal structural or chromosomal anomalies. Induction of labor for PROM (PROM group) was compared to induction for other indications (no-PROM group); the primary outcome measure was the cesarean section rate...
November 2017: Geburtshilfe und Frauenheilkunde
https://www.readbyqxmd.com/read/29199806/selective-progesterone-receptor-modulators-new-possibilities-for-gynecologic-hormone-therapy
#5
Nanna Sarvilinna, Leila Unkila-Kallio, Päivi Härkki, Aila Tiitinen, Oskari Heikinheimo
Progesterone regulates several female reproductive functions. Progesterone and synthetic progestins derived from it have long been utilized in gynecology. The effects of these steroids in target cells are mediated via progesterone receptors, Progesterone receptors are also the target of action of selective progesterone receptor modulators. Of the molecules of this newer group of drugs, two are presently in clinical use. Mifepristone is used in nonsurgical abortion, in softening of the cervix before surgical abortion, and in the induction of labor in cases of intrauterine death...
2017: Duodecim; Lääketieteellinen Aikakauskirja
https://www.readbyqxmd.com/read/29166819/pregnancy-outcomes-among-women-with-asthma
#6
Haitham Baghlaf, Andrea R Spence, Nicholas Czuzoj-Shulman, Haim Arie Abenhaim
PURPOSE: The purpose of this study is to examine the association between maternal asthma and pregnancy, delivery and neonatal outcomes. MATERIALS AND METHODS: We carried out a retrospective cohort study using the Health Care Cost and Utilization Project-Nationwide Inpatient Sample (HCUP-NIS) database from 2003 to 2011. Among women who delivered during this time period, we compared pregnancy, delivery, and neonatal outcomes in asthmatics versus non-asthmatics. Multivariate logistic regression was used to estimate adjusted odds ratios and 95% confidence intervals...
November 22, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29161752/prenatal-megacystis-is-prediction-of-outcome-and-renal%C3%A2-function-possible
#7
Regina Tschannen, Rita Gobet, Josef Wisser
Objective To assess prenatal prognostic criteria for fetuses with megacystis in order to counsel parents. Methods In a retrospective observational study at a single tertiary referral center, we assessed the clinical course of 53 fetuses with megacystis cared for at the Department of Obstetrics of the University Hospital Zurich between 1995 and 2008 and followed them up for 2 to 12 years. We determined fetal karyotype, amniotic fluid volume and fetal urinary biochemistry as prenatal prognostic factors...
November 21, 2017: Ultraschall in der Medizin
https://www.readbyqxmd.com/read/29157196/perinatal-outcomes-of-hypertensive-disorders-in-pregnancy-at-a-tertiary-hospital-in-ghana
#8
Kwame Adu-Bonsaffoh, Michael Y Ntumy, Samuel A Obed, Joseph D Seffah
BACKGROUND: Hypertensive disorders in pregnancy remain a major global health issue not only because of the associated high adverse maternal outcomes but there is a close accompaniment of significant perinatal morbidity and mortality especially in Sub-Saharan Africa (SSA). However, the perinatal burden of HDP in Ghana has not been explored. We conducted this study to determine the perinatal outcomes of HDP at a tertiary hospital in Ghana. METHODS: A cross-sectional study conducted between January to February 2013 at Korle Bu Teaching Hospital (KBTH) in Accra, Ghana...
November 21, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29146013/-chronic-histiocytic-intervillositis-diagnosis-and-management
#9
A Mekinian, N Costedoat-Chalumeau, L Carbillon, A Coulomb-L'Hermine, V Le Guern, A Masseau, E Lazaro, J Cohen, M Bornes, G Kayem, O Fain
Chronic intervillositis is a rare condition, which is associated with severe obstetrical outcome and high recurrence rate. Obstetrical adverse events are intrauterine growth restriction, recurrent early miscarriages, intrauterine deaths and prematurity by placental insufficiency. The determination of the extension and the intensity of the chronic intervillositis are not currently standardized. High rates of recurrence have been described, but actually there is no reliable predictive biomarker. No treatment is currently validated, but the use of immunomodulatory drugs could be justified by the possible autoimmune or allo-immune origin...
November 13, 2017: La Revue de Médecine Interne
https://www.readbyqxmd.com/read/29142561/feto-maternal-outcomes-and-glycemic-control-in-metformin-versus-insulin-treated-gestational-diabetics
#10
Rabia Arshad, Samia Khanam, Fuad Shaikh, Nasim Karim
Objective: To evaluate and compare feto-maternal outcomes and glycemic control in metformin versus insulin treated gestational diabetics. Methods: The study was conducted in 2010- 2012 as a part of M. Phil at Civil hospital, Lyari General Hospital and Mamji Hospital in Karachi. After written informed consent, 71 GDM diagnosed females with WHO criteria were enrolled. They were divided into two groups. Group-A, 32 females were given oral metformin 500 mg TDS while Group-B, 39 females were given insulin 0...
September 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/29122542/twin-twin-transfusion-syndrome-what-we-have-learned-from-clinical-trials
#11
REVIEW
Fatiha Djaafri, Julien Stirnemann, Imen Mediouni, Claire Colmant, Yves Ville
Monochorionic twin pregnancies are at increased risk for adverse outcome compared to dichorionic twin pregnancies and singletons. Monochorionic-specific complications include twin-twin transfusion syndrome (TTTS), twin anemia-polycythemia sequence, single intrauterine fetal demise and its consequences on the co-twin, and selective intrauterine growth restriction. Whereas the natural history of monochorionic-specific complications carries a high risk of fetal death or severe neurologic disability, a framework now exists, based on well-designed clinical trials, for optimal treatment of these entities...
November 6, 2017: Seminars in Fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29113299/microrna-210-suppresses-glucocorticoid-receptor-expression-in-response-to-hypoxia-in-fetal-rat-cardiomyocytes
#12
Shannalee R Martinez, Qingyi Ma, Chiranjib Dasgupta, Xianmei Meng, Lubo Zhang
Hypoxia is a common intrauterine stressor, often resulting in intrauterine growth restriction and increased risk for cardiovascular disease later in life. The aim of this work was to test the hypothesis that microRNA-210 (miR-210) mediates the detrimental suppression of glucocorticoid receptor (GR) in response to hypoxia in fetal rat cardiomyocytes. Cardiomyocytes isolated from gestational day 21 Sprague Dawley fetal rats showed increased miR-210 levels and reduced GR abundance after exposure to ex vivo hypoxia (1% O2)...
October 6, 2017: Oncotarget
https://www.readbyqxmd.com/read/29110976/emergency-medicine-myths-ectopic-pregnancy-evaluation-%C3%A2-risk%C3%A2-factors-and-presentation
#13
Jennifer J Robertson, Brit Long, Alex Koyfman
BACKGROUND: Ectopic pregnancy (EP) is an important cause of morbidity and mortality in females of reproductive age. Proper diagnosis and treatment are critical, as complications such as rupture, hemorrhagic shock, and even death can occur. OBJECTIVE: EP is a condition emergency physicians are trained to detect, yet there are multiple myths concerning its evaluation and diagnosis. This article reviews several of these myths in order to improve emergency department (ED) evaluation and diagnosis...
October 27, 2017: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29105047/hepatitis-e-virus-seroprevalence-in-pregnant-women-in-pakistan-maternal-and-fetal-outcomes
#14
Najma Javed, Sultana H Ullah, Nazli Hussain, Munir A Sheikh, Ambreen Khan, Farkhanda Ghafoor, Rukhsana Firdous, Waqar Uddin, Arif N Saqib, Ghazal Muhyudin
Hepatitis E virus (HEV) is endemic in Pakistan. Although otherwise asymptomatic, HEV infection becomes fatal in pregnancy, with considerable maternal and fetal morbidity and mortality. We conducted a descriptive study from April to October 2015 in 10 tertiary care hospitals throughout Pakistan to determine maternal and fetal morbidity and mortality in HEV-positive pregnant women with acute jaundice or raised liver function tests. Twenty-one of 135 women were HEV positive and in 3rd trimester except for 1 in 1st trimester...
October 30, 2017: Eastern Mediterranean Health Journal, la Revue de Santé de la Méditerranée Orientale
https://www.readbyqxmd.com/read/29102365/pregnancy-in-women-with-a-cardiomyopathy-outcomes-and-predictors-from-a-retrospective-cohort
#15
Gilles Billebeau, Martin Etienne, Riadh Cheikh-Khelifa, Daniele Vauthier-Brouzes, Estelle Gandjbakhch, Richard Isnard, Jacky Nizard, Michel Komajda, Marc Dommergues, Philippe Charron
BACKGROUND: Pregnancies in women with pre-existing cardiomyopathies are considered at high risk for complications. However, few data are available to characterize their natural history and predict the outcome. AIMS: Our aim was to evaluate the prevalence and predictors of acute cardiac and obstetric events in women with a cardiomyopathy during pregnancy, excluding peripartum cardiomyopathy. METHODS: In this retrospective study in a referral centre for cardiomyopathies, we included 43 consecutive pregnancies in 36 women with dilated, hypertrophic, arrhythmogenic right ventricular or tachycardia-induced cardiomyopathy, or left ventricular non-compaction...
October 25, 2017: Archives of Cardiovascular Diseases
https://www.readbyqxmd.com/read/29096233/parvovirus-b19-infection-in-pregnancy-awareness-and-opportunities
#16
REVIEW
Francesca Bonvicini, Gloria Bua, Giorgio Gallinella
Parvovirus B19 (B19V) is a human pathogenic virus associated with a wide range of clinical conditions. In pregnancy, B19V poses a potential hazard to the fetus as crossing the placental barrier and infecting erythroid progenitor cells in bone marrow and liver, it blocks fetal erythropoiesis leading to profound anemia, hydrops and/or fetal death. The virus is not regarded as a teratogen, however more scientific awareness is emerging on mechanisms and consequences of intrauterine infection and possible sequelae in the neonatal development...
October 26, 2017: Current Opinion in Virology
https://www.readbyqxmd.com/read/29094369/effect-of-inter-twin-delivery-interval-on-umbilical-artery-ph-and-apgar-score-in-the-second-twin
#17
Alon Tal, Hadar Peretz, Gali Garmi, Noah Zafran, Shabtai Romano, Raed Salim
BACKGROUND: To examine the effect of inter-twin delivery interval on umbilical artery pH and Apgar score of the second twin after vaginal delivery of the first twin. METHODS: Retrospective study conducted at a single teaching hospital. All pregnant women with twin gestation who delivered the first twin vaginally at more than 24 weeks between 1995 and 2015 were included. Major malformations and intrauterine deaths of one or both twins were excluded. Women were divided into those who had an inter-twin delivery interval of less than 30 minutes (group 1) or 30 minutes or more (group 2)...
November 2, 2017: Birth
https://www.readbyqxmd.com/read/29094052/maternal-and-perinatal-outcome-in-women-with-systemic-lupus-erythematosus-a-retrospective-bicenter-cohort-study
#18
Sylvia J Kroese, Carolien N H Abheiden, Birgit S Blomjous, Jacob M van Laar, Ronald W H M Derksen, Irene E M Bultink, Alexandre E Voskuyl, A Titia Lely, Marjon A de Boer, Johanna I P de Vries, Ruth D E Fritsch-Stork
Objective: To investigate disease activity around and during pregnancy and pregnancy outcome in women with systemic lupus erythematosus (SLE) considering antiphospholipid antibody status. Moreover, differences between first and consecutive pregnancies were examined. Methods: Pregnancies > 16 weeks gestation of SLE patients receiving joint care from rheumatologists and gynecologists in two tertiary centers in the Netherlands between 2000 and 2015 were included...
2017: Journal of Immunology Research
https://www.readbyqxmd.com/read/29082054/expectant-management-leading-to-successful-vaginal-delivery-following-intrauterine-fetal-death-in-a-woman-with-an-incarcerated-uterus
#19
Masafumi Yamamoto, Mio Takami, Ryosuke Shindo, Michi Kasai, Shigeru Aoki
Expectant management leads to successful vaginal delivery following intrauterine fetal death in a woman with an incarcerated uterus. Management of intrauterine fetal death in the second or third trimester of pregnancy in women with an incarcerated uterus is challenging. We report a case of successful vaginal delivery following intrauterine fetal death by expectant management in a woman with an incarcerated uterus. In cases of intrauterine fetal death in women with an incarcerated uterus, vaginal delivery may be possible if the incarceration is successfully reduced...
2017: Case Reports in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29076544/non-immune-hydrops-fetalis-do-placentomegaly-and-polyhydramnios-matter
#20
Victoria K Berger, Teresa N Sparks, Angie C Jelin, Chris Derderian, Cerine Jeanty, Kristen Gosnell, Tippi Mackenzie, Juan M Gonzalez
OBJECTIVES: Polyhydramnios and placentomegaly are commonly observed in nonimmune hydrops fetalis (NIHF); however, whether their ultrasonographic identification is relevant for prognosis is controversial. We evaluated outcomes of fetal or neonatal death and preterm birth (PTB) in cases of NIHF alone and in those with polyhydramnios and/or placentomegaly (P/PM). METHODS: We conducted a retrospective cohort of singletons with NIHF evaluated between 1994 and 2013. Nonimmune hydrops fetalis was defined as 2 or more abnormal fluid collections, including ascites, pericardial effusion, pleural effusion, and skin edema...
October 27, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
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