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https://www.readbyqxmd.com/read/28805889/oxytocin-injections-in-the-postpartal-period-affect-mammary-tight-junctions-in-sows
#1
C Farmer, M Lessard, C H Knight, H Quesnel
The potential impacts of injecting oxytocin (OXY) to sows in the early postpartum period on the quality of mammary tight junctions, milk composition, and immune status of sows and piglets were studied. Postparturient sows received i.m. injections of either saline (control [CTL]; = 10) or 75 IU of OXY ( = 10). Injections were given twice daily (0800 and 1630 h) starting on d 2 of lactation (i.e., between 12 and 20 h after birth of the last piglet), totaling 4 injections. Milk samples were obtained before the first injection (d 2 morning [AM]), before the second injection (d 2 afternoon [PM]), and on d 4 PM and d 5 PM...
August 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/28805116/bisphenol-a-and-adverse-pregnancy-outcomes-a-systematic-review-of-the-literature
#2
Vasilios Pergialiotis, Paraskevi Kotrogianni, Evangelos Christopoulos-Timogiannakis, Diamanto Koutaki, Georgios Daskalakis, Nikolaos Papantoniou
PURPOSE: Bisphenol A is a chemical compound related to adverse maternal and neonatal outcomes. The purpose of the present systematic review is to summarize current knowledge in the field. MATERIALS AND METHODS: We systematically searched the Medline (1966-2017), Scopus (2004-2017), Clinicaltrials.gov (2008-2017), Cochrane Central Register of Controlled Trials CENTRAL (1999-2017) databases. RESULTS: Thirty-five studies were included in the present systematic review...
August 14, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28802704/early-miscarriage-rate-in-lean-polycystic-ovary-syndrome-women-after-euploid-embryo-transfer-a-matched-pair-study
#3
Lu Luo, Fang Gu, Huying Jie, Chenhui Ding, Qiang Zhao, Qiong Wang, Canquan Zhou
The early miscarriage rate is reported to be higher in patients with polycystic ovary syndrome (PCOS) compared with non-PCOS patients. However, whether PCOS is an independent risk factor for early miscarriage is still controversial; to what extent embryonic aneuploidy accounts for miscarriages of PCOS is still unknown. In this 1:3 matched-pair study, 67 lean PCOS patients and 201 controls matched for age, body mass index (BMI) and embryo scores undergoing a single euploid blastocyst transfer in vitrified-warmed cycles were analysed...
July 29, 2017: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/28802092/utility-of-capture-recapture-methodology-to-estimate-prevalence-of-congenital-heart-defects-among-adolescents-in-11-new-york-state-counties-2008-to-2010
#4
Tugba Akkaya-Hocagil, Wan-Hsiang Hsu, Kristin Sommerhalter, Claire McGarry, Alissa Van Zutphen
BACKGROUND: Congenital heart defects (CHDs) are the most common birth defects in the United States, and the population of individuals living with CHDs is growing. Though CHD prevalence in infancy has been well characterized, better prevalence estimates among children and adolescents in the United States are still needed. METHODS: We used capture-recapture methods to estimate CHD prevalence among adolescents residing in 11 New York counties. The three data sources used for analysis included Statewide Planning and Research Cooperative System (SPARCS) hospital inpatient records, SPARCS outpatient records, and medical records provided by seven pediatric congenital cardiac clinics from 2008 to 2010...
August 12, 2017: Birth defects research
https://www.readbyqxmd.com/read/28801384/causes-of-and-contributors-to-infant-mortality-in-a-rural-community-of-north-india-evidence-from-verbal-and-social-autopsy
#5
Sanjay Kumar Rai, Shashi Kant, Rahul Srivastava, Priti Gupta, Puneet Misra, Chandrakant Sambhaji Pandav, Arvind Kumar Singh
OBJECTIVE: To identify the medical causes of death and contribution of non-biological factors towards infant mortality by a retrospective analysis of routinely collected data using verbal and social autopsy tools. SETTING: The study site was Health and Demographic Surveillance System (HDSS), Ballabgarh, North India PARTICIPANTS: All infant deaths during the years 2008-2012 were included for verbal autopsy and infant deaths from July 2012 to December 2012 were included for social autopsy...
August 11, 2017: BMJ Open
https://www.readbyqxmd.com/read/28797657/systematic-review-of-transabdominal-cerclage-placed-via-laparoscopy-for-the-prevention-of-preterm-birth
#6
REVIEW
Gaby N Moawad, Paul Tyan, Tracey Bracke, Elias D Abi Khalil, Vicky Vargas, Alexis Gimovsky, Cherie Marfori
Preterm birth is the leading cause of neonatal mortality and morbidity. Multiple interventions have been put in place to minimize this occurrence. Despite current recommendations including medical management, cervical length screening, and transvaginal cerclage a substantial number of women still experience preterm birth. For those patients, experts recommend a transabdominal cerclage. In our systematic review, we compare 26 studies (1116 patients) on transabdominal cerclage placed via laparotomy (TAC-lap) to 15 studies (728 patients) on transabdominal cerclage placed via laparoscopy (TAC-lsc)...
August 7, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28796691/neonatal-outcomes-of-low-risk-late-preterm-twins-compared-with-late-preterm-singletons
#7
Shimrit Yaniv Salem, Mia Kibel, Elizabeth Asztalos, Arthur Zaltz, Jon Barrett, Nir Melamed
OBJECTIVE: To test the hypothesis that the risk of neonatal morbidity among late-preterm twins is similar to that of late-preterm singletons. METHODS: We conducted a retrospective cohort study of all women with twin or singleton pregnancy who gave birth during the late-preterm period in a single tertiary center between 2008 and 2015. Neonatal outcomes of low-risk, late-preterm twins were compared with those of low-risk, late-preterm singletons. The primary outcome was the same primary composite respiratory morbidity variable that was used in the randomized controlled trial of Gyamfi-Bannerman et al on the administration of antenatal corticosteroids during the late-preterm period...
August 4, 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28792689/predictive-value-of-neurodevelopmental-outcome-and-serum-tau-protein-level-in-neonates-with-hypoxic-ischemic-encephalopathy
#8
Hong-Yan Lv, Su-Jing Wu, Xiu-Ling Gu, Qiu-Li Wang, Peng-Shun Ren, Yan Ma, Li-Ying Peng, Lin-Hong Jin, Lian-Xiang Li
BACKGROUND: Tau protein is s specific protein expressed by neurons in the central nervous system. Elevated serum Tau protein is associated with many diseases of the central nervous system. The serum Tau protein level in neonates with hypoxic ischemic encephalopathy (HIE) is still poorly understood. METHODS: Forty-one human neonates with HIE and thirty-five healthy neonates (control group) within 24 hours after birth were studied. Tau protein in serum was detected by enzyme-linked immunosorbent assay...
July 1, 2017: Clinical Laboratory
https://www.readbyqxmd.com/read/28791290/placental-malaria-a-new-insight-into-the-pathophysiology
#9
REVIEW
Lalita Sharma, Geeta Shukla
Malaria in pregnancy poses a great health risk to mother and her fetus and results into complications, such as abortion, still birth, intra uterine growth retardation, and low birth weight. The heavy infiltration of Plasmodium falciparum-infected RBCs in the intervillous spaces of placenta seems to be responsible for all the complications observed. Infected RBCs in the placenta cause an inflammatory environment with increase in inflammatory cells and cytokines which is deleterious to the placenta. Increased inflammatory responses in the infected placenta result into oxidative stress that in turn causes oxidative stress-induced placental cell death...
2017: Frontiers in Medicine
https://www.readbyqxmd.com/read/28783242/re-conceptualising-stillbirth-and-revisiting-birth-surveillance
#10
K S Joseph, Melanie Basso, Cheryl Davies, Lily Lee
The increased focus on stillbirth related issues in recent years has brought several previously neglected issues 'out of the shadows' [1] and highlighted the need for greater preventive efforts and better care for bereaved mothers and families. Some issues (such as the option of cesarean delivery for fetal death at late gestation [2], viewing the fetus following pregnancy termination for a fetal anomaly [3,4] and acknowledgement of paternal grief and anxiety [5]) reflect a substantial shift from previous traditions in clinical practice...
August 7, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28775187/a-qualitative-study-of-pregnancy-related-anxiety-among-women-in-tanzania
#11
Melanie King Rosario, Shahirose Sadrudin Premji, Elias Charles Nyanza, Shelley Raffin Bouchal, David Este
OBJECTIVES: To explore and understand the experiences and priorities of pregnant women living with fears and worries related to fetal/infant and maternal health, the birthing process and ability to parent the infant (ie, pregnancy-related anxiety (PRA)) in Mwanza, Tanzania. DESIGN: Descriptive phenomenological approach. SETTING: Two clinics in the Ilemela and Nyamagana districts of Mwanza. PARTICIPANTS: Pregnant and postpartum women who obtained high scores on a PRA scale during pregnancy in a larger quantitative study were contacted to participate in an interview (10 women, aged 18-34 years; 3 HIV positive)...
August 3, 2017: BMJ Open
https://www.readbyqxmd.com/read/28770411/effect-of-iodine-nutrition-on-pregnancy-outcomes-in-an-iodine-sufficient-area-in-china
#12
Yue Xiao, Huakun Sun, Chenyan Li, Yongze Li, Shiqiao Peng, Chenling Fan, Weiping Teng, Zhongyan Shan
Many studies focused on the association between thyroid disease and pregnancy outcomes. The present study explored the effect of iodine nutrition during the first trimester on pregnancy outcomes. One thousand five hundred sixty-nine pregnant, euthyroid women at ≤12 weeks of gestation in an iodine-sufficient area in China were recruited. According to the World Health Organization (WHO) criteria for iodine nutrition during pregnancy, participants were divided into four groups: adequate iodine (median urinary iodine concentration (UIC), 150-249 μg/L), mild deficiency (UIC, 100-150 μg/L), moderate and severe deficiency (UIC, <100 μg/L), and more than adequate and excessive (UIC, ≥250 μg/L) groups...
August 2, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28770125/seasonality-epidemiology-and-outcome-of-congenital-diaphragmatic-hernia-in-south-west-of-iran
#13
Masoud Dehdashtian, Shiva Bashirnejad, Arash Malekian, Mohammad Reza Aramesh, Mohammad Hasan Aletayeb
INTRODUCTION: The pathogenesis of congenital diaphragmatic hernia (CDH) is not clear. Risk factors including environmental factors have been implicated in the pathogenesis of few congenital anomalies. We aimed to assess the effect of season on the incidence of CDH and mortality rate in the southwest of Iran. MATERIAL AND METHODS: In this retrospective study, the records of 60 patients with CDH who were admitted at Neonatal Intensive Care Unit (NICU) of Imam Khomeini Hospital of Ahvaz, Iran were evaluated...
April 2017: Journal of Neonatal Surgery
https://www.readbyqxmd.com/read/28768747/how-innate-is-locomotion-in-precocial-animals-a-study-on-the-early-development-of-spatio-temporal-gait-variables-and-gait-symmetry-in-piglets
#14
Charlotte Vanden Hole, Jana Goyens, Sara Prims, Erik Fransen, Miriam Ayuso Hernando, Steven Van Cruchten, Peter Aerts, Chris Van Ginneken
Locomotion is one of the most important ecological functions in animals. Precocial animals, such as pigs, are capable of independent locomotion shortly after birth. This raises the question whether coordinated movement patterns and the underlying muscular control in these animals is fully innate or whether there still exists a rapid maturation. We addressed this question by studying gait development in neonatal pigs through the analysis of spatio-temporal gait characteristics during locomotion at self-selected speed...
August 1, 2017: Journal of Experimental Biology
https://www.readbyqxmd.com/read/28764293/the-serological-evidence-of-cytomegalovirus-infection-as-a-potent-aetiological-factor-for-cleft-lip-palate-mental-retardation-and-deafness
#15
D V Divya, Madu Ghana Shyam Prasad, Ambati Naga Radhakrishna, S Pavani Reddy, K Pratyusha, K V K Santosh Kumar, R V Sandeep
INTRODUCTION: Congenital Cytomegalovirus (CCMV) infection is estimated to occur in 0.5% to 2% of all deliveries across the world. According to the available literature about Human Cytomegalovirus (HCMV) infected children, 0.5% to 1% acquire Cytomegalovirus (CMV) in utero, 40% acquire the infection within the first decade of life, between 15% to 70% acquire CMV infection in group day care settings and continue to shed the virus for 6 to 48 months after primary infection. Although, 90% of the infected infants are clinically asymptomatic at birth, shreds of evidence show that these infants are at risk for audiological, neurological, and developmental sequelae...
June 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28761387/abortion-an-increasing-public-health-concern-in-ecuador-a-10-year-population-based-analysis
#16
Esteban Ortiz-Prado, Katherine Simbaña, Lenin Gómez, Anna M Stewart-Ibarra, Lisa Scott, Gabriel Cevallos-Sierra
OBJECTIVES: To describe the epidemiology of abortion in Ecuador from 2004 to 2014 and compare the prevalence between the public and the private health care systems. METHODS: This is a cross-sectional analysis of the overall mortality and morbidity rate due to abortion in Ecuador, based on public health records and other government databases. RESULTS: From 2004 to 2014, a total of 431,614 spontaneous abortions, miscarriage and other types of abortions were registered in Ecuador...
2017: Pragmatic and Observational Research
https://www.readbyqxmd.com/read/28761202/admission-test-and-pregnancy-outcome
#17
Setareh Akhavan, Parvaneh Lak, Fatemeh Rahimi-Sharbaf, Seyed Rahim Mohammadi, Mahboobeh Shirazi
BACKGROUND: The admission test (AT) has been carried out for many years, but there are still debates about the prognostic value of the test. Therefore, we aimed to examine the value of the AT in predicting the adverse outcome in neonates. METHODS: In this cross-sectional study, 425 pregnant women with normal vaginal delivery were studied between2009 and 2014at Vali-e-Asr Hospital. Based on the results, the women were divided into 2groups of normal and abnormal ATs...
July 2017: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28759773/high-incidence-of-maternal-parvovirus-b19-infection-in-a-large-unselected-population-based-pregnancy-cohort-in-norway
#18
Regine Barlinn, Halvor Rollag, Lill Trogstad, Kirsti Vainio, Coraline Basset, Per Magnus, Susanne G Dudman
BACKGROUND: Around 40% of pregnant women in Norway are parvovirus B19 (B19V) seronegative and thus at risk for B19 V infection. Studies on samples from women with symptomatic disease or known exposure have shown that nucleic acid amplification assays combined with serology increase the sensitivity and improves the diagnostic procedure. OBJECTIVES: The aim was to investigate the seroprevalence of B19V infection, the occurrence of new infections and vertical transmission in a population-based pregnancy cohort, with special emphasis on the diagnostic methods...
July 20, 2017: Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology
https://www.readbyqxmd.com/read/28759408/variation-in-formula-supplementation-of-breastfed-newborn-infants-in-new-york-hospitals
#19
Trang Nguyen, Barbara A Dennison, Wei Fan, Changning Xu, Guthrie S Birkhead
OBJECTIVES: We examined the variation between 126 New York hospitals in formula supplementation among breastfed infants after adjusting for socioeconomic, maternal, and infant factors and stratifying by level of perinatal care. METHODS: We used 2014 birth certificate data for 160 911 breastfed infants to calculate hospital-specific formula supplementation percentages by using multivariable hierarchical logistic regression models. RESULTS: Formula supplementation percentages varied widely among hospitals, from 2...
July 2017: Pediatrics
https://www.readbyqxmd.com/read/28758375/all-bereaved-parents-are-entitled-to-good-care-after-stillbirth-a-mixed-methods-multicentre-study-insight
#20
D Siassakos, S Jackson, K Gleeson, C Chebsey, A Ellis, C Storey
OBJECTIVE: To understand challenges in care after stillbirth and provide tailored solutions. DESIGN: Multi-centre case study. SETTING: Three maternity hospitals. POPULATION: Parents with a stillborn baby, maternity staff. METHODS: Thematic analysis of parent interviews and staff focus groups and service provision investigation. OUTCOMES: 1 Themes; 2 Triangulation matrix; 3 Recommendations...
July 31, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
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