Evyn Peters, Arash Shamloo, Rohit J Lodhi, Gene Marcoux, Kylie Jackson, Shawn Halayka, Lloyd Balbuena
BACKGROUND: Real world evidence about antipsychotics focuses on rehospitalization. Modeling the time course of pharmacotherapy would show patients' adherence to medications and physicians' adherence to medication guidelines. We aimed to calculate the cumulative time spent in second generation antipsychotics (SGAs), gaps, antipsychotic polypharmacy, and clozapine in discharged schizophrenia patients. METHODS: Hospitalization and pharmacy dispensing data from 2008-2018 in Manitoba, Saskatchewan, and British Columbia were linked and an electronic cohort ( N = 2,997) was created (mean follow-up: 49 months, SD = 38)...
2022: Frontiers in Psychiatry