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https://www.readbyqxmd.com/read/28736507/national-mortality-burden-due-to-communicable-non-communicable-and-other-diseases-in-ethiopia-1990-2015-findings-from-the-global-burden-of-disease-study-2015
#1
Awoke Misganaw, Tilahun N Haregu, Kebede Deribe, Gizachew Assefa Tessema, Amare Deribew, Yohannes Adama Melaku, Azmeraw T Amare, Semaw Ferede Abera, Molla Gedefaw, Muluken Dessalegn, Yihunie Lakew, Tolesa Bekele, Mesoud Mohammed, Biruck Desalegn Yirsaw, Solomon Abrha Damtew, Kristopher J Krohn, Tom Achoki, Jed Blore, Yibeltal Assefa, Mohsen Naghavi
BACKGROUND: Ethiopia lacks a complete vital registration system that would assist in measuring disease burden and risk factors. We used the Global Burden of Diseases, Injuries, and Risk Factors Study 2015 (GBD 2015) estimates to describe the mortality burden from communicable, non-communicable, and other diseases in Ethiopia over the last 25 years. METHODS: GBD 2015 mainly used cause of death ensemble modeling to measure causes of death by age, sex, and year for 195 countries...
2017: Population Health Metrics
https://www.readbyqxmd.com/read/28736506/national-disability-adjusted-life-years-dalys-for-257-diseases-and-injuries-in-ethiopia-1990-2015-findings-from-the-global-burden-of-disease-study-2015
#2
Awoke Misganaw, Yohannes Adama Melaku, Gizachew Assefa Tessema, Amare Deribew, Kebede Deribe, Semaw Ferede Abera, Muluken Dessalegn, Yihunie Lakew, Tolesa Bekele, Tilahun N Haregu, Azmeraw T Amare, Molla Gedefaw, Mesoud Mohammed, Biruck Desalegn Yirsaw, Solomon Abrha Damtew, Tom Achoki, Jed Blore, Kristopher J Krohn, Yibeltal Assefa, Mahlet Kifle, Mohsen Naghavi
BACKGROUND: Disability-adjusted life years (DALYs) provide a summary measure of health and can be a critical input to guide health systems, investments, and priority-setting in Ethiopia. We aimed to determine the leading causes of premature mortality and disability using DALYs and describe the relative burden of disease and injuries in Ethiopia. METHODS: We used results from the Global Burden of Diseases, Injuries, and Risk Factors Study 2015 (GBD 2015) for non-fatal disease burden, cause-specific mortality, and all-cause mortality to derive age-standardized DALYs by sex for Ethiopia for each year...
2017: Population Health Metrics
https://www.readbyqxmd.com/read/28735773/today-s-fentanyl-crisis-prohibition-s-iron-law-revisited
#3
Leo Beletsky, Corey S Davis
More than a decade in the making, America's opioid crisis has morphed from being driven by prescription drugs to one fuelled by heroin and, increasingly, fentanyl. Drawing on historical lessons of the era of National Alcohol Prohibition highlights the unintended, but predictable impact of supply-side interventions on the dynamics of illicit drug markets. Under the Iron Law of Prohibition, efforts to interrupt and suppress the illicit drug supply produce economic and logistical pressures favouring ever-more compact substitutes...
June 26, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/28735401/determination-of-enzymes-associated-with-sulfite-toxicity-in-plants-kinetic-assays-for-so-apr-sir-and-in-gel-sir-activity
#4
Galina Brychkova, Assylay Kurmanbayeva, Aizat Bekturova, Inna Khozin, Dominic Standing, Dmitry Yarmolinsky, Moshe Sagi
The amino acid cysteine plays a major role in plant response to abiotic stress by being the donor of elemental sulfur for the sulfuration of the molybdenum cofactor, otherwise the last step of ABA biosynthesis, the oxidation of abscisic aldehyde, is inactivated. Additionally, cysteine serves as a precursor for the biosynthesis of glutathione, the reactive oxygen species scavenger essential for redox status homeostasis during stress. Cysteine is generated by the sulfate reductive pathway where sulfite oxidase (SO; EC 1...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28735183/reductive-dechlorination-of-trichloroethylene-by-polyvinylpyrrolidone-stabilized-nanoscale-zerovalent-iron-particles-with-ni
#5
Macharla Arun Kumar, Sungjun Bae, Seunghee Han, Yoonseok Chang, Woojin Lee
We developed a novel stabilized nanoscale zerovalent iron (NZVI) particles with Ni using an electron conducting polymer, polyvinylpyrrolidone (PVP), to selectively dechlorinate trichloroethylene (TCE) to non-toxic intermediates. The size of the PVP stabilized NZVI-Ni ((PVP-NZVI-Ni), average diameter: ∼20nm) is smaller than that of bare NZVI (50-80nm) due to the prevention of agglomeration of the resultant iron particles by PVP. PVP-NZVI-Ni showed a complete removal of TCE in 1h with superior dechlorination kinetics (kobs=5...
July 14, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/28735157/effects-of-adhesions-of-amorphous-fe-and-al-hydroxides-on-surface-charge-and-adsorption-of-k-and-cd-2-on-rice-roots
#6
Zhao-Dong Liu, Hai-Cui Wang, Qin Zhou, Ren-Kou Xu
Iron (Fe) and aluminum (Al) hydroxides in variable charge soils attached to rice roots may affect surface-charge properties and subsequently the adsorption and uptake of nutrients and toxic metals by the roots. Adhesion of amorphous Fe and Al hydroxides onto rice roots and their effects on zeta potential of roots and adsorption of potassium (K(+)) and cadmium (Cd(2+)) by roots were investigated. Rice roots adsorbed more Al hydroxide than Fe hydroxide because of the greater positive charge on Al hydroxide. Adhesion of Fe and Al hydroxides decreased the negative charge on rice roots, and a greater effect of the Al hydroxide...
July 20, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28734957/effect-of-schwertmannite-and-jarosite-on-the-formation-of-hypoxic-blackwater-during-inundation-of-grass-material
#7
Chamindra L Vithana, Leigh A Sullivan, Troy Shepherd
This study focused on understanding the effect of schwertmannite and jarosite, commonly found in floodplains containing acid sulfate soil materials, on the characteristics of the hypoxic blackwaters that can form when floodplain vegetation experiences prolonged inundation. The formation of these 'blackwaters' was simulated in the laboratory by inundating flood-intolerant pasture grass leaf material in both the presence of schwertmannite/jarosite (schwertmannite and jarosite treatments) minerals and their absence (control treatment) at 27...
July 17, 2017: Water Research
https://www.readbyqxmd.com/read/28733821/zero-valent-iron-particles-for-pcb-degradation-and-an-evaluation-of-their-effects-on-bacteria-plants-and-soil-organisms
#8
Alena Ševců, Yehia S El-Temsah, Jan Filip, Erik J Joner, Kateřina Bobčíková, Miroslav Černík
Two types of nano-scale zero-valent iron (nZVI-B prepared by borohydride reduction and nZVI-T produced by thermal reduction of iron oxide nanoparticles in H2) and a micro-scale ZVI (mZVI) were compared for PCB degradation efficiency in water and soil. In addition, the ecotoxicity of nZVI-B and nZVI-T particles in treated water and soil was evaluated on bacteria, plants, earthworms, and ostracods. All types of nZVI and mZVI were highly efficient in degradation of PCBs in water, but had little degradation effect on PCBs in soil...
July 22, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28732970/ultrasonic-assisted-synthesis-of-palladium-nickel-iron-oxide-core-shell-nanoalloys-as-effective-catalyst-for-suzuki-miyaura-and-p-nitrophenol-reduction-reactions
#9
Najmeh Ghanbari, S Jafar Hoseini, Mehrangiz Bahrami
In this study, ultrasonic assisted synthesis of Pd-Ni/Fe3O4 core-shell nanoalloys is reported. Unique reaction condition was prepared by ultrasonic irradiation, releasing the stored energy in the collapsed bubbles and heats the bubble contents that leads to Pd(II) and Ni(II) reduction. Co-precipitation method was applied for the synthesis of Fe3O4 nanoparticles (NPs). Immobilized solution was produced by sonicating the aqueous mixture of Fe3O4 and mercaptosuccinic acid to obtain Pd-Ni alloys on Fe3O4 magnetic NP cores...
November 2017: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/28732867/nano-iron-oxide-impregnated-in-chitosan-bead-as-a-highly-efficient-sorbent-for-cr-vi-removal-from-water
#10
Jianbo Lu, Kai Xu, Jinmei Yang, Yarong Hao, Fang Cheng
Using Fe(III) salts and chitosan, nano iron oxide impregnated in chitosan bead (NIOC) was successfully synthesized for aqueous Cr(VI) detoxification via sol-gel technique without any additional crosslinking agent. NIOC characterization demonstrated that the iron in NIOC mainly existed as nano akaganeite (β-FeOOH) and complex with chitosan. Intraparticle diffusion was the major rate-limiting step. The maximal adsorption capacity was 69.8mg/g (pH 5.0, 20°C). Normal concentration of coexisting anions (SO4(2-), CO3(2-), SiO3(2)-) showed insignificant competition, whereas PO4(3-) suppressed the Cr(VI) sorption...
October 1, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28732542/national-disability-adjusted-life-years-dalys-for-257-diseases-and-injuries-in-ethiopia-1990-2015-findings-from-the-global-burden-of-disease-study-2015
#11
Awoke Misganaw, Yohannes Adama Melaku, Gizachew Assefa Tessema, Amare Deribew, Kebede Deribe, Semaw Ferede Abera, Muluken Dessalegn, Yihunie Lakew, Tolesa Bekele, Tilahun N Haregu, Azmeraw T Amare, Molla Gedefaw, Mesoud Mohammed, Biruck Desalegn Yirsaw, Solomon Abrha Damtew, Tom Achoki, Jed Blore, Kristopher J Krohn, Yibeltal Assefa, Mahlet Kifle, Mohsen Naghavi
BACKGROUND: Disability-adjusted life years (DALYs) provide a summary measure of health and can be a critical input to guide health systems, investments, and priority-setting in Ethiopia. We aimed to determine the leading causes of premature mortality and disability using DALYs and describe the relative burden of disease and injuries in Ethiopia. METHODS: We used results from the Global Burden of Diseases, Injuries, and Risk Factors Study 2015 (GBD 2015) for non-fatal disease burden, cause-specific mortality, and all-cause mortality to derive age-standardized DALYs by sex for Ethiopia for each year...
July 21, 2017: Population Health Metrics
https://www.readbyqxmd.com/read/28732536/national-mortality-burden-due-to-communicable-non-communicable-and-other-diseases-in-ethiopia-1990-2015-findings-from-the-global-burden-of-disease-study-2015
#12
Awoke Misganaw, Tilahun N Haregu, Kebede Deribe, Gizachew Assefa Tessema, Amare Deribew, Yohannes Adama Melaku, Azmeraw T Amare, Semaw Ferede Abera, Molla Gedefaw, Muluken Dessalegn, Yihunie Lakew, Tolesa Bekele, Mesoud Mohammed, Biruck Desalegn Yirsaw, Solomon Abrha Damtew, Kristopher J Krohn, Tom Achoki, Jed Blore, Yibeltal Assefa, Mohsen Naghavi
BACKGROUND: Ethiopia lacks a complete vital registration system that would assist in measuring disease burden and risk factors. We used the Global Burden of Diseases, Injuries, and Risk Factors Study 2015 (GBD 2015) estimates to describe the mortality burden from communicable, non-communicable, and other diseases in Ethiopia over the last 25 years. METHODS: GBD 2015 mainly used cause of death ensemble modeling to measure causes of death by age, sex, and year for 195 countries...
July 21, 2017: Population Health Metrics
https://www.readbyqxmd.com/read/28732146/medicago-truncatula-zinc-iron-permease6-provides-zinc-to-rhizobia-infected-nodule-cells
#13
Isidro Abreu, Ángela Saéz, Rosario Castro-Rodríguez, Viviana Escudero, Benjamín Rodríguez-Haas, Marta Senovilla, Camille Larue, Daniel Grolimund, Manuel Tejada-Jiménez, Juan Imperial, Manuel González-Guerrero
Zinc is a micronutrient required for symbiotic nitrogen fixation. It has been proposed that in model legume Medicago truncatula, zinc is delivered by the root vasculature into the nodule and released in the infection/differentiation zone. There, transporters must introduce this element into rhizobia-infected cells to metallate the apoproteins that use zinc as a cofactor. MtZIP6 (Medtr4g083570) is a M. truncatula Zinc-Iron Permease (ZIP) that is expressed only in roots and nodules, with the highest expression levels in the infection/differentiation zone...
July 21, 2017: Plant, Cell & Environment
https://www.readbyqxmd.com/read/28732010/biofilm-imaging-in-porous-media-by-laboratory-x-ray-tomography-combining-a-non-destructive-contrast-agent-with-propagation-based-phase-contrast-imaging-tools
#14
Maxence Carrel, Mario A Beltran, Verónica L Morales, Nicolas Derlon, Eberhard Morgenroth, Rolf Kaufmann, Markus Holzner
X-ray tomography is a powerful tool giving access to the morphology of biofilms, in 3D porous media, at the mesoscale. Due to the high water content of biofilms, the attenuation coefficient of biofilms and water are very close, hindering the distinction between biofilms and water without the use of contrast agents. Until now, the use of contrast agents such as barium sulfate, silver-coated micro-particles or 1-chloronaphtalene added to the liquid phase allowed imaging the biofilm 3D morphology. However, these contrast agents are not passive and potentially interact with the biofilm when injected into the sample...
2017: PloS One
https://www.readbyqxmd.com/read/28731079/a-polymeric-temozolomide-nanocomposite-against-orthotopic-glioblastoma-xenograft-tumor-specific-homing-directed-by-nestin
#15
Suma Prabhu, Jayant Sastri Goda, Srinivas Mutalik, Bhabani Shankar Mohanty, Pradip Chaudhari, Sharada Rai, Nayanabhirama Udupa, Bola Sadashiva Satish Rao
The development of effective therapeutic strategies for glioblastoma faces challenges such as modulating the blood brain barrier (BBB) for drug influx and selectively targeting tumor cells. Nanocarrier drug delivery strategies are functionalized to enhance vascular permeability. We engineered superparamagnetic iron oxide nanoparticle (SPION) based polymeric nanocomposites (84.37 ± 12.37 nm / 101.56 ± 7.42 nm) embedding temozolomide (TMZ) targeted against glioblastoma by tagging an antibody against nestin, a stem cell marker, and transferrin / polysorbate-80 to permeate the BBB...
July 21, 2017: Nanoscale
https://www.readbyqxmd.com/read/28731078/a-mononuclear-iron-carbonyl-complex-fe-%C3%AE-bdt-co-2-pta-2-with-bulky-phosphine-ligands-a-model-for-the-fefe-hydrogenase-enzyme-active-site-with-an-inverted-redox-potential
#16
M Natarajan, H Faujdar, S M Mobin, M Stein, S Kaur-Ghumaan
A mononuclear hexa-coordinated iron carbonyl complex [Fe(μ-bdt)(CO)2(PTA)2] 1 (bdt = 1,2-benzenedithiolate; PTA = 1,3,5-triaza-7-phosphaadamantane) with two bulky phosphine ligands in the trans position was synthesized and characterized by X-ray structural analysis coulometry data, FTIR, electrochemistry and electronic structure calculations. The complex undergoes a facilitated two-electron reduction 1/12- and shows an inverted one-electron reduction for 1/1- at higher potentials. Electrochemical investigations of 1 are compared to the closely related [Fe(bdt)(CO)2(PMe3)2] compound...
July 21, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28730560/impairment-of-ntca-gene-revealed-its-role-in-regulating-iron-homeostasis-ros-production-and-cellular-phenotype-under-iron-deficiency-in-cyanobacterium-anabaena-sp-pcc-7120
#17
Manish Singh Kaushik, Meenakshi Srivastava, Anumeha Singh, Arun Kumar Mishra
Iron deficiency ends up into several unavoidable consequences including damaging oxidative stress in cyanobacteria. NtcA is a global nitrogen regulator controls wide range of metabolisms in addition to regulation of nitrogen metabolism. In present communication, NtcA based regulation of iron homeostasis, ROS production and cellular phenotype under iron deficiency in Anabaena 7120 has been investigated. NtcA regulates the concentration dependent iron uptake by controlling the expression of furA gene. NtcA also regulated pigment synthesis and phenotypic alterations in Anabaena 7120...
August 2017: World Journal of Microbiology & Biotechnology
https://www.readbyqxmd.com/read/28729857/nutrient-acquisition-and-the-metabolic-potential-of-photoferrotrophic-chlorobi
#18
Katharine J Thompson, Rachel L Simister, Aria S Hahn, Steven J Hallam, Sean A Crowe
Anoxygenic photosynthesis evolved prior to oxygenic photosynthesis and harnessed energy from sunlight to support biomass production on the early Earth. Models that consider the availability of electron donors predict that anoxygenic photosynthesis using Fe(II), known as photoferrotrophy, would have supported most global primary production before the proliferation of oxygenic phototrophs at approximately 2.3 billion years ago. These photoferrotrophs have also been implicated in the deposition of banded iron formations, the world's largest sedimentary iron ore deposits that formed mostly in late Archean and early Proterozoic Eons...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28727296/chitosan-fe-iii-complex-as-a-phosphate-chelator-in-uraemic-rats-a-novel-treatment-option
#19
Wander Barros do Carmo, Bárbara Bruna Abreu Castro, Clóvis Antônio Rodrigues, Melani Ribeiro Custódio, Helady Sanders-Pinheiro
Phosphate retention and hyperphosphataemia are associated with increased mortality in chronic kidney disease (CKD) patients. We tested the use of cross-linked iron chitosan III (CH-FeCl) as a potential phosphate chelator in rats with CKD. We evaluated 96 animals, divided equally into 4 groups (control, CKD, CH-FeCl, and CKD/CH-FeCl), over 7 weeks. We induced CKD by feeding animals an adenine-enriched diet (0.75% in the first 4 weeks and 0.1% in the following 3 weeks). We administered 30 mg/kg daily of the test polymer, by gavage, from the third week until the end of the study...
July 20, 2017: Basic & Clinical Pharmacology & Toxicology
https://www.readbyqxmd.com/read/28726936/dithiolato-and-halogenido-bridged-nickel-iron-complexes-related-to-the-active-site-of-nife-h2ases-preparation-structures-and-electrocatalytic-h2-production
#20
Li-Cheng Song, Xiao-Feng Han, Wei Chen, Jia-Peng Li, Xu-Yong Wang
A new series of the structural and functional models for the active site of [NiFe]-H2ases has been prepared by a simple and convenient synthetic route. Thus, treatment of diphosphines RN(PPh2)2 (1a, R = p-MeC6H4CH2; 1b, R = EtO2CCH2) with an equimolar NiCl2·6H2O, NiBr2·3H2O, and NiI2 in refluxing CH2Cl2/MeOH or EtOH gave the mononuclear Ni complexes RN(PPh2)2NiX2 (2a, R = p-MeC6H4CH2, X = Cl; 2b, R = EtO2CCH2, X = Cl; 3a, R = p-MeC6H4CH2, X = Br; 3b, R = EtO2CCH2, X = Br; 4a, R = p-MeC6H4CH2, X = I; 4b, R = EtO2CCH2, X = I) in 67-97% yields...
July 20, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
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