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https://www.readbyqxmd.com/read/28743141/variations-in-tibial-tuberosity-to-trochlear-groove-and-posterior-cruciate-ligament-distances-due-to-tibial-external-and-valgus-rotations
#1
Bradley W Smith, Emily A Millar, Kerwyn C Jones, John J Elias
No abstract text is available yet for this article.
July 25, 2017: Journal of Knee Surgery
https://www.readbyqxmd.com/read/28743030/reactive-ceo2-nanofluids-for-uv-protective-films
#2
Rafael Maniglia, Kenneth J Reed, John Texter
We investigate surface modification by organo-trimethoxysilanes of nano-ceria and if such surface-modified nano-ceria can be transformed into solvent-free nanofluids. We also examine whether simultaneous modification with ionic liquid salts and with acrylate groups yields nanofluids suitable for forming UV-protective films and clear coatings by UV-initiated polymerization. Nominally 3nm diameter CeO2 was successfully synthesized and surface decorated with an ionic liquid salt and with acrylate groups to produce a core/shell structured solvent-free nanofluid after ion exchange of chloride for a soft polyoxyethylene sulfonate anion...
July 18, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28742999/adding-polyamine-metabolism-to-the-mtorc1-toolkit-in-cell-growth-and-cancer
#3
Ana P Gomes, Tanya Schild, John Blenis
The mammalian/mechanistic target of rapamycin complex 1 (mTORC1) is a major nutrient sensor and regulator of cellular metabolic flux. Reporting recently in Nature, Zabala-Letona et al. (2017) show that mTORC1 regulates an additional branch of metabolism in the cell-polyamine synthesis-that is important for prostate cancer tumorigenicity.
July 24, 2017: Developmental Cell
https://www.readbyqxmd.com/read/28742978/consideration-for-eliminating-conjunctival-closure-in-the-enucleation-procedure
#4
John D Pemberton, Hugh Wright, Brian T Fowler, Juliet Kim, James C Fleming
To compare post-operative results and complications in patients who undergo enucleation with or without suture closure of the conjunctiva. This was a retrospective chart review study. Review of 50 cases of enucleation surgery at the University of Arkansas for Medical Sciences and Arkansas Children's Hospital between July 2011 and December 2014. Criteria for inclusion in the study were all cases of enucleation that had extraocular muscles attached to a spherical orbital implant with or without conjunctival closure, and at least 2 months of postoperative follow up...
July 25, 2017: Orbit
https://www.readbyqxmd.com/read/28742964/conformational-flexibility-and-self-association-of-fibrinogen-in-concentrated-solutions
#5
Yuriy F Zuev, Rustem I Litvinov, Alexander E Sitnitsky, Bulat Z Idiyatullin, Dilyafruz R Bakirova, Dennis Galanakis, Artem Zhmurov, Valeri Barsegov, John W Weisel
We studied the hydrodynamic behavior of fibrinogen, a blood plasma protein involved in blood clotting, in a broad 0.3-60 mg/ml range of concentration and 5-42°C temperature using pulsed-field gradient 1H NMR-diffusometry. Arrhenius plots revealed the activation energy for fibrinogen diffusion Ed = 21.3 kJ/mol at 1.4 mg/ml and 28.4 kJ/mol at 38 mg/ml. We found a dramatic slowdown in fibrinogen self-diffusion with concentration beginning at 1.7-3.4 mg/ml, which deviated from the standard hard-particle behavior, suggesting a remarkable intermolecular entanglement...
July 25, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28742932/a-pilot-randomized-clinical-trial-testing-integrated-twelve-step-facilitation-itsf-treatment-for-adolescent-substance-use-disorder
#6
John F Kelly, Yifrah Kaminer, Christopher W Kahler, Bettina Hoeppner, Julie Yeterian, Julie V Cristello, Christine Timko
BACKGROUND AND AIMS: Integration of 12-step philosophy and practices is common in adolescent substance use disorder (SUD) treatment programs, particularly in North America. However, although numerous experimental studies have tested 12-step facilitation (TSF) treatments among adults, no studies have tested TSF-specific treatments for adolescents. We tested the efficacy of a novel integrated TSF. DESIGN: Explanatory, parallel-group, randomized clinical trial comparing 10 sessions of either motivational enhancement therapy/cognitive-behavioral therapy (MET/CBT; n=30) or a novel integrated TSF (iTSF; n=29) with follow-up assessments at 3-, 6-, and 9-months following treatment entry...
July 25, 2017: Addiction
https://www.readbyqxmd.com/read/28742835/a-checklist-of-the-bats-of-peninsular-malaysia-and-progress-towards-a-dna-barcode-reference-library
#7
Voon-Ching Lim, Rosli Ramli, Subha Bhassu, John-James Wilson
Several published checklists of bat species have covered Peninsular Malaysia as part of a broader region and/or in combination with other mammal groups. Other researchers have produced comprehensive checklists for specific localities within the peninsula. To our knowledge, a comprehensive checklist of bats specifically for the entire geopolitical region of Peninsular Malaysia has never been published, yet knowing which species are present in Peninsular Malaysia and their distributions across the region are crucial in developing suitable conservation plans...
2017: PloS One
https://www.readbyqxmd.com/read/28742794/the-cost-effectiveness-of-screening-for-ovarian-cancer-results-from-the-uk-collaborative-trial-of-ovarian-cancer-screening-ukctocs
#8
Usha Menon, Alistair J McGuire, Maria Raikou, Andy Ryan, Susan K Davies, Matthew Burnell, Aleksandra Gentry-Maharaj, Jatinderpal K Kalsi, Naveena Singh, Nazar N Amso, Derek Cruickshank, Stephen Dobbs, Keith Godfrey, Jonathan Herod, Simon Leeson, Tim Mould, John Murdoch, David Oram, Ian Scott, Mourad W Seif, Karin Williamson, Robert Woolas, Lesley Fallowfield, Stuart Campbell, Steven J Skates, Mahesh Parmar, Ian J Jacobs
BACKGROUND: To assess the within-trial cost-effectiveness of an NHS ovarian cancer screening (OCS) programme using data from UKCTOCS and extrapolate results based on average life expectancy. METHODS: Within-trial economic evaluation of no screening (C) vs either (1) an annual OCS programme using transvaginal ultrasound (USS) or (2) an annual ovarian cancer multimodal screening programme with serum CA125 interpreted using a risk algorithm (ROCA) and transvaginal ultrasound as a second-line test (MMS), plus comparison of lifetime extrapolation of the no screening arm and the MMS programme using both a predictive and a Markov model...
July 25, 2017: British Journal of Cancer
https://www.readbyqxmd.com/read/28742746/aortic-regurgitation
#9
John M Graffeo, Harrynauth Persaud
No abstract text is available yet for this article.
August 2017: JAAPA: Official Journal of the American Academy of Physician Assistants
https://www.readbyqxmd.com/read/28742724/epidemiology-of-noninvasive-ventilation-in-pediatric-cardiac-icus
#10
Ryan A Romans, Steven M Schwartz, John M Costello, Nikhil K Chanani, Parthak Prodhan, Avihu Z Gazit, Andrew H Smith, David S Cooper, Jeffrey Alten, Kshitij P Mistry, Wenying Zhang, Janet E Donohue, Michael Gaies
OBJECTIVE: To describe the epidemiology of noninvasive ventilation therapy for patients admitted to pediatric cardiac ICUs and to assess practice variation across hospitals. DESIGN: Retrospective cohort study using prospectively collected clinical registry data. SETTING: Pediatric Cardiac Critical Care Consortium clinical registry. PATIENTS: Patients admitted to cardiac ICUs at PC4 hospitals. INTERVENTIONS: None...
July 22, 2017: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/28742713/does-prolonged-enteral-feeding-with-supplemental-omega-3-fatty-acids-impact-on-recovery-post-esophagectomy-results-of-a-randomized-double-blind-trial
#11
Laura A Healy, Aoife Ryan, Suzanne L Doyle, Éadaoin Bríd Ní Bhuachalla, Samantha Cushen, Ricardo Segurado, Thomas Murphy, Narayanasamy Ravi, Claire L Donohoe, John V Reynolds
OBJECTIVE: This randomized controlled trial (RCT) hypothesized that prolonged enteral nutrition (EN) with supplemental eicosapentanoic acid (EPA), an omega-3 fatty acid with immune and anabolic properties, may impact on clinical and nutritional outcomes. BACKGROUND: Esophagectomy is associated with significant weight loss and catabolism, and negatively impacts quality of life (QL). Strategies to counter sustained catabolism have therapeutic rationale. METHODS: This multicenter, double-blind, placebo-controlled RCT was powered on a 5% difference in lean body mass (LBM) at 1 month...
July 24, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28742711/readiness-of-us-general-surgery-residents-for-independent-practice
#12
Brian C George, Jordan D Bohnen, Reed G Williams, Shari L Meyerson, Mary C Schuller, Michael J Clark, Andreas H Meier, Laura Torbeck, Samuel P Mandell, John T Mullen, Douglas S Smink, Rebecca E Scully, Jeffrey G Chipman, Edward D Auyang, Kyla P Terhune, Paul E Wise, Jennifer N Choi, Eugene F Foley, Justin B Dimick, Michael A Choti, Nathaniel J Soper, Keith D Lillemoe, Joseph B Zwischenberger, Gary L Dunnington, Debra A DaRosa, Jonathan P Fryer
OBJECTIVE: This study evaluates the current state of the General Surgery (GS) residency training model by investigating resident operative performance and autonomy. BACKGROUND: The American Board of Surgery has designated 132 procedures as being "Core" to the practice of GS. GS residents are expected to be able to safely and independently perform those procedures by the time they graduate. There is growing concern that not all residents achieve that standard. Lack of operative autonomy may play a role...
July 24, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28742639/idiopathic-intracranial-hypertension-progressing-to-venous-sinus-thrombosis-subarachnoid-hemorrhage-and-stroke
#13
Joshua S Hardin, Raghu H Ramakrishnaiah, John D Pemberton, Paul H Phillips, Joseph G Chacko
Idiopathic intracranial hypertension (IIH) is a syndrome characterized by increased intracranial pressure (ICP), the absence of structural lesions on neuroimaging, and normal cerebrospinal fluid composition. Cerebral venous sinus thrombosis (CVST) is a common cause of increased ICP and can be differentiated from IIH with magnetic resonance venography. We describe a young woman with typical IIH who underwent lumbar puncture and was treated with a short course of high-dose corticosteroids followed by acetazolamide...
July 24, 2017: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/28742605/predictors-of-the-biomechanical-effects-of-customized-foot-orthoses-in-adults-with-flat-arched-feet
#14
John B Arnold, Thomas May, Christopher Bishop
OBJECTIVE: To determine the potential presence and characteristics of biomechanical responders to customized foot orthoses during walking in adults with flat-arched feet. DESIGN: Experimental, repeated-measures. SETTING: University clinic and laboratory. PARTICIPANTS: Eighteen symptom-free adults with flat-arched feet. INTERVENTIONS: Customized foot orthoses. MAIN OUTCOME MEASURES: In-shoe foot biomechanics were measured during walking with and without customized foot orthoses using 3D analysis...
July 21, 2017: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
https://www.readbyqxmd.com/read/28742503/pth-and-pthr1-in-osteocytes-new-insights-into-old-partners
#15
Maria P Yavropoulou, Alexandros Michopoulos, John G Yovos
Parathyroid hormone receptors are present in bone cells and play a crucial role in the maintenance of skeletal integrity, bone homeostasis and regulation of calcium and phosphate metabolism. Although the function of these receptors has long being recognized in the cells of the osteoblastic lineage regulating directly osteoblast differentiation and function and indirectly osteoclastogenesis, recent findings demonstrate their functional presence in osteocytes participating in the co-ordination of bone remodelling...
April 2017: Hormones: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28742479/understanding-and-combating-resistance-to-online-learning
#16
John Vivolo
Resistance to change is an easy thing for human beings to understand. It is at the heart of our desire to find comfort with the familiar such as family, friends and our homes. We create homes that are designed a certain way and usually are slow to change. We make friends for years and keep those memories etched in stone, even though time and age create a romanticised version of the past. Change scares us so much that we reflect on our past, the old days, with such reverence that we paint over the ugly parts...
December 1, 2016: Science Progress
https://www.readbyqxmd.com/read/28742457/epidemic-network-analysis-for-mitigation-of-invasive-pathogens-in-seed-systems-potato-in-ecuador
#17
Christopher Buddenhagen, John Hernandez Nopsa, Kelsey F Andersen, Jorge Andrade-Piedra, Greg Forbes, Peter Kromann, Sara Thomas-Sharma, Pilar Useche, Karen A Garrett
Seed systems have an important role in the distribution of high quality seed and improved varieties. The structure of seed networks also helps to determine the epidemiological risk for seedborne disease. We present a new method for evaluating the epidemiological role of nodes in seed networks, and apply it to a regional potato farmer consortium (CONPAPA) in Ecuador. We surveyed farmers to estimate the structure of networks of farmer seed tuber and ware potato transactions, and farmer information sources about pest and disease management...
July 25, 2017: Phytopathology
https://www.readbyqxmd.com/read/28742437/health-and-safety-adoption-from-use-of-a-risk-assessment-document-on-irish-farms
#18
John McNamara, Patrick Griffin, James Kinsella, James Phelan
OBJECTIVES: This paper describes levels of implementation of occupational health and safety (OHS) controls on a sample of Irish farms following completion of a risk assessment document (RAD) made available as part of a statutory code of practice (COP) for the agriculture sector. The paper describes the legislation mandating the COP and the operation of a prevention initiative (PI) among key stakeholders to develop and promote farmer use of the COP and RAD. METHODS: RADs were collected for farmers (n = 475) and the number and type of OHS controls listed for action were tabulated...
July 25, 2017: Journal of Agromedicine
https://www.readbyqxmd.com/read/28742318/development-of-a-virtual-cell-model-to-predict-cell-response-to-substrate-topography
#19
Tiam Heydari, Maziar Heidari, Omid Mashinchian, Michal Wojcik, Ke Xu, Matthew John Dalby, Morteza Mahmoudi, Mohammad Reza Ejtehadi
Cells can sense and respond to changes in the topographical, chemical, and mechanical information in their environment. Engineered substrates are increasingly being developed that exploit these physical attributes to direct cell responses (most notably mesenchymal stem cells) and therefore control cell behavior toward desired applications. However, there are very few methods available for robust and accurate modeling that can predict cell behavior prior to experimental evaluations and this typically means that many cell test iterations are needed to identify best material features...
July 25, 2017: ACS Nano
https://www.readbyqxmd.com/read/28742285/variable-expressivity-and-incomplete-penetrance-in-a-large-family-with-non-classical-diamond-blackfan-anemia-associated-with-ribosomal-protein-l11-splicing-variant
#20
Colleen M Carlston, Zeinab A Afify, Janice C Palumbos, Heidi Bagley, Carlos Barbagelata, Whitney L Wooderchak-Donahue, Rong Mao, John C Carey
Diamond-Blackfan anemia (DBA) is a group of clinically and genetically heterogeneous bone marrow failure disorders with or without congenital anomalies. Variable expressivity and incomplete penetrance have been observed within affected families. Diamond-Blackfan anemia-7 (DBA7), caused by heterozygous mutations in ribosomal protein L11 (RPL11), accounts for approximately 5% of DBA. DBA7 is usually characterized by early-onset bone marrow failure often accompanied by congenital malformations, especially thumb defects...
July 25, 2017: American Journal of Medical Genetics. Part A
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