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https://www.readbyqxmd.com/read/29788831/lumbosacral-transitional-vertebrae-in-cats-and-its-relationship-to-lumbosacral-vertebral-canal-stenosis
#1
Georgina Harris, Jessica Ball, Steven De Decker
Objectives Although a clear relationship has been demonstrated between the presence of lumbosacral transitional vertebrae and the development of lumbosacral stenosis in dogs, this relationship has not been evaluated in cats. The aim of this study was to investigate the relationship between the presence of lumbosacral transitional vertebrae and lumbosacral stenosis in cats. Methods The medical records and diagnostic imaging studies of 13 cats diagnosed with lumbosacral stenosis were retrospectively reviewed for lumbosacral abnormalities and compared with findings of 405 cats that underwent CT for reasons unrelated to spinal disease...
May 1, 2018: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/29595359/feline-hyperaesthesia-syndrome-with-self-trauma-to-the-tail-retrospective-study-of-seven-cases-and-proposal-for-integrated-multidisciplinary-diagnostic-approach
#2
Pablo Amengual Batle, Clare Rusbridge, Tim Nuttall, Sarah Heath, Katia Marioni-Henry
Case series summary This was a retrospective study on the clinical features and response to treatment in seven cats with feline hyperaesthesia syndrome (FHS) and tail mutilation. FHS is a poorly understood disorder characterised by skin rippling over the dorsal lumbar area, episodes of jumping and running, excessive vocalisation, and tail chasing and self-trauma. The majority of the cats were young, with a median age of 1 year at the onset of clinical signs, male (n = 6) and with access to the outdoors (n = 5)...
March 1, 2018: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/29521279/flexible-microelectrode-array-for-interfacing-with-the-surface-of-neural-ganglia
#3
Zachariah J Sperry, Kyounghwan Na, Saman S Parizi, Hillel J Chiel, John Seymour, Euisik Yoon, Tim M Bruns
OBJECTIVE: The dorsal root ganglia (DRG) are promising nerve structures for sensory neural interfaces because they provide centralized access to primary afferent cell bodies and spinal reflex circuitry. In order to harness this potential, new electrode technologies are needed which take advantage of the unique properties of DRG, specifically the high density of neural cell bodies at the dorsal surface. Here we report initial in vivo results from the development of a flexible non-penetrating polyimide electrode array interfacing with the surface of ganglia...
June 2018: Journal of Neural Engineering
https://www.readbyqxmd.com/read/29325196/ventral-slot-surgery-to-manage-cervical-intervertebral-disc-disease-in-three-cats
#4
Abbe Harper Crawford, Rodolfo Cappello, Akash Alexander, Steven De Decker
OBJECTIVE:  This case series describes the clinical presentation, management and outcome of three cats diagnosed with cervical intervertebral disc disease that underwent decompressive ventral slot surgery. METHODS:  This is a retrospective case series evaluating client-owned cats undergoing a ventral slot surgical procedure to manage cervical intervertebral disc disease ( n  = 3). RESULTS:  A routine ventral slot surgery was performed in each case without complication, resulting in postoperative neurological improvement in all three cases...
January 2018: Veterinary and Comparative Orthopaedics and Traumatology: V.C.O.T
https://www.readbyqxmd.com/read/29314212/lumbar-to-sacral-root-rerouting-to-restore-bladder-function-in-a-feline-spinal-cord-injury-model-urodynamic-and-retrograde-nerve-tracing-results-from-a-pilot-study
#5
Ornella Lam Van Ba, Mary F Barbe, Romain Caremel, Shachar Aharony, Oleg Loutochin, Line Jacques, Matthew W Wood, Ekta Tiwari, Gerald F Tuite, Lysanne Campeau, Jacques Corcos, Michael R Ruggieri
AIMS: Lumbar to sacral rerouting surgery can potentially allow voiding via a skin-central nervous system-bladder reflex pathway. Here, we assessed if this surgery was effective in treating neurogenic bladder dysfunction/sphincter in felines. METHODS: Eight cats underwent spinal cord transection (SCT) at thoracic level 10/11. Unilateral L7 to S1 ventral root anastomosis was performed 1 month later in six cats. Two cats served as transection-only controls. Electrical and manual stimulation of L6-S1 dermatomes, and urodynamics were performed at 3, 5, 7, and 9/10 months post transection...
January 2018: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/29276623/feline-vertebral-angiomatosis-two-cases
#6
Massimo Frizzi, Nicola Ottolini, Claudia Spigolon, Giovanna Bertolini
Case series summary: Two cats aged between 1 and 2 years were presented for paraparesis, general discomfort, back pain and urinary retention. Extradural spinal cord compression at the level of T4 and T8 was evident on CT examination and on MRI. Hemilaminectomy and partial corpectomy were performed to achieve spinal cord decompression. Histopathology of the abnormal bone tissue was suggestive of vertebral angiomatosis. After initially worsening, both cats recovered their normal gait and functional urination...
July 2017: JFMS Open Reports
https://www.readbyqxmd.com/read/29157191/neuronal-vacuolization-in-feline-panleukopenia-virus-infection
#7
Vanessa M Pfankuche, Wendy K Jo, Erhard van der Vries, Nicole Jungwirth, Stephan Lorenzen, Albert D M E Osterhaus, Wolfgang Baumgärtner, Christina Puff
Feline panleukopenia virus (FPV) infections are typically associated with anorexia, vomiting, diarrhea, neutropenia, and lymphopenia. In cases of late prenatal or early neonatal infections, cerebellar hypoplasia is reported in kittens. In addition, single cases of encephalitis are described. FPV replication was recently identified in neurons, although it is mainly found in cells with high mitotic activity. A female cat, 2 months old, was submitted to necropsy after it died with neurologic deficits. Besides typical FPV intestinal tract changes, multifocal, randomly distributed intracytoplasmic vacuoles within neurons of the thoracic spinal cord were found histologically...
March 2018: Veterinary Pathology
https://www.readbyqxmd.com/read/28966357/feline-meningoencephalomyelitis-of-unknown-origin-a-retrospective-analysis-of-16-cases
#8
Arianna Negrin, Sarah Spencer, Giunio Bruto Cherubini
This study aimed to describe the signalment, clinical signs, magnetic resonance imaging (MRI) findings, cerebrospinal fluid (CSF) analysis, treatment, and outcome of feline meningoencephalomyelitis of unknown origin (FMUO). Medical records from 16 cats meeting the inclusion criteria of CSF pleocytosis, negative CSF polymerase chain reaction (PCR)-infectious disease results, and characteristic MRI findings were retrospectively reviewed. Median age was 9.4 years. Clinical signs included ataxia, proprioceptive deficits, seizures, and spinal hyperesthesia...
October 2017: Canadian Veterinary Journal. la Revue Vétérinaire Canadienne
https://www.readbyqxmd.com/read/28955476/periaortic-lymphoma-in-a-cat
#9
Laura Bree, Chiara Bergamino, Ronan Mullins, Pamela Kelly, Robert Shiel
CASE SUMMARY: A 14-year-old neutered male Siamese cat was presented with a 3 month history of lethargy, inappetence, dehydration, hindlimb ataxia and intermittent proprioceptive deficits in the hindlimbs. Physical examination revealed low body condition score (1.75/5), pallor and bilateral basilar grade II/VI systolic heart murmur. Neurological examination revealed hindlimb ataxia, severe atrophy of the hindlimb musculature, intermittent hindlimb proprioceptive deficits and normoreflexia...
July 2017: JFMS Open Reports
https://www.readbyqxmd.com/read/28782181/public-regulatory-databases-as-a-source-of-insight-for-neuromodulation-devices-stimulation-parameters
#10
REVIEW
Doe Kumsa, G Karl Steinke, Gregory F Molnar, Eric M Hudak, Fred W Montague, Shawn C Kelley, Darrel F Untereker, Alan Shi, Benjamin P Hahn, Chris Condit, Hyowon Lee, Dawn Bardot, Jose A Centeno, Victor Krauthamer, Pavel A Takmakov
OBJECTIVE: The Shannon model is often used to define an expected boundary between non-damaging and damaging modes of electrical neurostimulation. Numerous preclinical studies have been performed by manufacturers of neuromodulation devices using different animal models and a broad range of stimulation parameters while developing devices for clinical use. These studies are mostly absent from peer-reviewed literature, which may lead to this information being overlooked by the scientific community...
February 2018: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/28739165/quantitative-models-of-feline-lumbosacral-dorsal-root-ganglia-neuronal-cell-density
#11
Anastasia K Ostrowski, Zachariah J Sperry, Grant Kulik, Tim M Bruns
BACKGROUND: Dorsal root ganglia (DRG) are spinal root components that contain the cell bodies of converging primary sensory neurons. DRG are becoming a therapeutic target for electrical neural interfaces. Our purpose was to establish methods for quantifying the non-random nature and distribution of neuronal cell bodies within DRG. NEW METHOD: We identified neuronal cell body locations in 26 feline lumbosacral DRG cross-section histological images and used computational tools to quantify spatial trends...
October 1, 2017: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/28714062/splitting-the-difference-new-insights-into-distinguishing-features-of-human-versus-feline-models-of-adaptive-locomotor-control
#12
James M Finley
No abstract text is available yet for this article.
September 1, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/28599613/immunohistochemical-analysis-of-canine-and-feline-muscle-disorders-using-formalin-fixed-paraffin-embedded-tissues
#13
Takanori Shiga, Kazuyuki Uchida, James K Chambers, Hiroyuki Nakayama
Histochemical techniques used in examination of muscle biopsies typically require frozen sections. Given that most of the specimens submitted to a veterinary laboratory for diagnosis are formalin-fixed, the choice of staining methods is limited. We aimed to further advance the diagnostic capabilities of pathologists presented with formalin-fixed muscle samples and to describe the differences in immunohistopathologic findings between neurogenic and myogenic muscle disorders. Based on hematoxylin and eosin staining, we defined in dogs the histologic lesions in 4 neurogenic disorders (degenerative myelopathy and polyneuropathy) and 2 myogenic disorders (dystrophin-deficient muscular dystrophy)...
November 2017: Journal of Veterinary Diagnostic Investigation
https://www.readbyqxmd.com/read/28484114/vertebral-replacement-for-the-treatment-of-vertebral-osteosarcoma-in-a-cat
#14
Kohei Nakata, Harumi Miura, Hiroki Sakai, Takashi Mori, Sanae Shibata, Hidetaka Nishida, Sadatoshi Maeda, Hiroaki Kamishina
A 7-year-old cat was referred with pelvic limb ataxia. Radiography and CT revealed bone resorption of the L1 vertebral arch, and myelography identified a compressive extradural lesion. The mass was surgically removed and histopathologically diagnosed as giant cell osteosarcoma. Three years later, the recurrent tumor resection and vertebral fixation were performed. Six months later, vertebrectomy was performed to radically excise the recurrent mass and a titanium spinal cage was placed. The cat is alive approximately 5 years after the first surgery...
June 10, 2017: Journal of Veterinary Medical Science
https://www.readbyqxmd.com/read/28287078/the-design-of-and-chronic-tissue-response-to-a-composite-nerve-electrode-with-patterned-stiffness
#15
M J Freeberg, M A Stone, R J Triolo, D J Tyler
OBJECTIVE: As neural interfaces demonstrate success in chronic applications, a novel class of reshaping electrodes with patterned regions of stiffness will enable application to a widening range of anatomical locations. Patterning stiff regions and flexible regions of the electrode enables nerve reshaping while accommodating anatomical constraints of various implant locations ranging from peripheral nerves to spinal and autonomic plexi. APPROACH: Introduced is a new composite electrode enabling patterning of regions of various electrode mechanical properties...
June 2017: Journal of Neural Engineering
https://www.readbyqxmd.com/read/28156189/feline-glioma-a-retrospective-study-and-review-of-the-literature
#16
MULTICENTER STUDY
Daniel R Rissi, Andrew D Miller
Case series summary This study aimed to evaluate the pathologic and diagnostic features of 13 cases of feline glioma diagnosed at two veterinary diagnostic institutions over 16 years. A retrospective search was conducted using the laboratory information system. Selected cases were reviewed, tumors were classified according to the 2007 World Health Organization Classification of Tumours of the Central Nervous System, and tissue sections were submitted to an immunohistochemistry panel for further characterization...
December 2017: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/28113558/the-fabrication-implantation-and-stability-of-intraspinal-microwire-arrays-in-the-spinal-cord-of-cat-and-rat
#17
Jeremy A Bamford, R Marc Lebel, Kian Parseyan, Vivian K Mushahwar
Intraspinal microstimulation (ISMS) is currently under investigation for its ability to restore function following spinal cord injury and aid in addressing basic investigations of the spinal cord in feline and murine (rat) models. In this report we describe the procedures for fabricating and implanting intraspinal microwires, with special emphasis on the rat model. We also report our results on targeting success and long-term stability and functionality of the implants. Early targeting with implants fabricated based on general "average" dimensions of the spinal cord was approximately 50% successful in reaching the proper targets within the ventral grey matter in cats...
March 2017: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/28069392/characterization-and-validation-of-a-split-belt-treadmill-for-measuring-hindlimb-ground-reaction-forces-in-able-bodied-and-spinalized-felines
#18
Marko Dimiskovski, Richard Scheinfield, Dwight Higgin, Alexander Krupka, Michel A Lemay
BACKGROUND: The measurement of ground reaction forces (GRFs) in animals trained to locomote on a treadmill after spinal cord injury (SCI) could prove valuable for evaluating training outcomes; however, quantitative measures of the GRFs in spinal felines are limited. NEW METHOD: A split belt treadmill was designed and constructed to measure the GRFs of feline hindlimbs during stepping. The treadmill consists of two independent treadmill assemblies, each mounted on a force plate...
February 15, 2017: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/27687936/distribution-of-feline-lymphoma-in-the-central-and-peripheral-nervous-systems
#19
REVIEW
Maria Teresa Mandara, Luca Motta, Pietro Calò
In cats, lymphoma (lymphosarcoma) is the most common neoplasm affecting the spinal cord and the second most common intracranial tumour. Although lymphoma commonly develops in the spinal cord as a part of a multicentric process, a primary form may occur. Lymphoma can exhibit a wide range of morphological patterns, including intraparenchymal brain mass, lymphomatosis cerebri, intravascular lymphoma, lymphomatous choroiditis and meningitis, extradural, intradural-extramedullary or intramedullary lymphoma in the spinal cord, or neurolymphomatosis in the peripheral nerves...
October 2016: Veterinary Journal
https://www.readbyqxmd.com/read/27588458/first-report-of-systemic-toxoplasmosis-in-a-new-zealand-sea-lion-phocarctos-hookeri
#20
W D Roe, S Michael, J Fyfe, E Burrows, S A Hunter, L Howe
CASE HISTORY: A 1-year-old female New Zealand sea lion (Phocarctos hookeri) was intermittently observed in the Otago region of New Zealand over an 11-month period, always dragging her hind flippers. In December 2012 the sea lion was found dead, after a period of several days being observed to be harassed by male sea lions. PATHOLOGICAL FINDINGS: At gross postmortem examination the sea lion was in moderate body condition with signs of recent bite wounds and bruising...
January 2017: New Zealand Veterinary Journal
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