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https://www.readbyqxmd.com/read/28936176/chronic-intermittent-hypoxia-differentially-impacts-different-states-of-inspiratory-activity-at-the-level-of-the-preb%C3%A3-tzinger-complex
#1
Alfredo J Garcia, Tatiana Dashevskiy, Maggie A Khuu, Jan-Marino Ramirez
The preBötzinger complex (preBötC) is a medullary brainstem network crucially involved in the generation of different inspiratory rhythms. In the isolated brainstem slice, the preBötC reconfigures to produce different rhythms that we refer to as "fictive eupnea" under baseline conditions (i.e., carbogen), and "fictive gasping" in hypoxia. We recently demonstrated that fictive eupnea is irregular following exposure to chronic intermittent hypoxia (CIH). However, it is unknown how CIH impacts fictive gasping...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28935354/anti-n-methyl-d-aspartate-receptor-encephalitis-in-children-of-central-south-china-clinical-features-treatment-influencing-factors-and-outcomes
#2
Ying Wang, Weixi Zhang, Jinghua Yin, Qianjin Lu, Fei Yin, Fang He, Jing Peng
BACKGROUND AND PURPOSE: We analyzed the clinical manifestations of children with anti-N-methyl-d-aspartate receptor (anti-NMDAR) encephalitis in Central South China and the factors influencing the effectiveness of treatment. METHODS: A retrospective study of children (0-14years old) with anti-NMDAR encephalitis in Central South China was carried out from March 2014 to November 2016. Demographics, clinical features, treatment, outcome, and the factors influencing the effectiveness of treatment were reviewed...
September 11, 2017: Journal of Neuroimmunology
https://www.readbyqxmd.com/read/28935191/circadian-rhythm-and-autonomic-dysfunction-in-presymptomatic-and-early-huntington-s-disease
#3
Elena Bellosta Diago, Jesús Pérez Pérez, Sonia Santos Lasaosa, Alejandro Viloria Alebesque, Saül Martínez Horta, Jaime Kulisevsky, Javier López Del Val
INTRODUCTION: Sleep and circadian rhythm disturbances are common in patients with neurodegenerative diseases such as Huntington's disease (HD). The aim of this study was to evaluate variability in circadian blood pressure (BP) to determine the association between abnormal circadian BP and sleep quality in patients with HD. METHODS: Cross-sectional, multicenter study of 38 HD mutation carriers (23 premanifest and 15 early stage patients) who were compared to 38 age- and sex-matched controls...
September 15, 2017: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/28934524/associations-of-sleep-duration-and-disturbances-with-hypertension-in-metropolitan-cities-of-delhi-chennai-and-karachi-in-south-asia-cross-sectional-analysis-of-the-carrs-study
#4
Roopa Shivashankar, Dimple Kondal, Mohammed K Ali, Ruby Gupta, Rajendra Pradeepa, Viswanathan Mohan, Muhammad Masood Kadir, K M Venkat Narayan, Nikhil Tandon, Dorairaj Prabhakaran, Anne Peasey
Objectives: Sleep duration and disturbances may be risk factors for hypertension. Despite the high burden of hypertension in South Asia, little is known about this relationship in this region. Methods: We analyzed population-level cross-sectional data from the Centre for Cardiometabolic Risk Reduction in South Asia (CARRS) study that recruited representative samples of adults ≥ 20 years from three cities-Delhi, Chennai (India), and Karachi (Pakistan) during 2010-2011...
September 1, 2017: Sleep
https://www.readbyqxmd.com/read/28933667/diagnostic-performance-of-cheeks-appearance-in-sleep-apnea
#5
Aline Prikladnicki, Denis Martinez, Melissa Giacomelli Brunetto, Cintia Zappe Fiori, Maria do Carmo Sfreddo Lenz, Erissandra Gomes
OBJECTIVE: Obstructive sleep apnea (OSA) is a common, potentially life-threatening, but underdiagnosed condition. The study aimed to test the role of facial myofunctional alterations in OSA screening. METHOD: Sixty-one individuals with sleep complaints were evaluated by the Orofacial Myofunctional Evaluation with Scores (OMES) protocol before undergoing polysomnography. The performance of each of the protocol scores in OSA screening was tested. RESULTS: The nonparametric correlation of the apnea-hypopnea index (AHI) was significant for 18 of the 41 variables of the OMES protocol...
September 21, 2017: Cranio: the Journal of Craniomandibular Practice
https://www.readbyqxmd.com/read/28933604/the-nottingham-fatigue-after-stroke-notfast-study-factors-associated-with-severity-of-fatigue-in-stroke-patients-without-depression
#6
Avril Drummond, Louise Hawkins, Nikola Sprigg, Nick S Ward, Amit Mistri, Pippa Tyrrell, Gillian E Mead, Esme Worthington, Nadina B Lincoln
OBJECTIVE: To identify factors associated with post-stroke fatigue in a sample of stroke survivors without depression. DESIGN: Cross-sectional cohort study. SETTING: Recruitment was from four stroke units in the UK. SUBJECTS: Participants were assessed within four to six weeks of first stroke; those with high levels of depressive symptoms (score ⩾7 Brief Assessment Schedule Depression Cards) were excluded. MAIN MEASURES: Participants were assessed after stroke on the Fatigue Severity Scale of the Fatigue Assessment Inventory, the Rivermead Mobility Index, Nottingham Extended Activities of Daily Living scale, Beck Anxiety Index, Sleep Hygiene Index, 6m walk test, and measures of cognitive ability...
October 2017: Clinical Rehabilitation
https://www.readbyqxmd.com/read/28933313/sleep-wake-difficulties-in-community-dwelling-cancer-patients-receiving-palliative-care-subjective-and-objective-assessment
#7
Marie Solange Bernatchez, Josée Savard, Marie-Hélène Savard, Michèle Aubin, Hans Ivers
OBJECTIVE: Prevalence rates of sleep difficulties in advanced cancer patients have varied widely across studies (12 to 96%), and none of these employed a diagnostic interview to distinguish different types of sleep-wake disorders. Moreover, very limited information is available on subjective and objective sleep parameters in this population. Our study was conducted in palliative cancer patients and aimed to assess rates of sleep-wake disorders and subsyndromal symptoms and to document subjective and objective sleep-wake parameters across various types of sleep-wake difficulties...
September 21, 2017: Palliative & Supportive Care
https://www.readbyqxmd.com/read/28932922/decreased-ocular-blood-flow-after-photocoagulation-therapy-in-neonatal-retinopathy-of-prematurity
#8
Tadashi Matsumoto, Takashi Itokawa, Tomoaki Shiba, Masahiko Tomita, Kotaro Hine, Norio Mizukaki, Hitoshi Yoda, Yuichi Hori
PURPOSE: To evaluate the relationships between optic nerve head blood flow, expressed as mean blur rate (MBR) measured by laser speckle flowgraphy (LSFG), and photocoagulation therapy in neonates with retinopathy of prematurity (ROP). STUDY DESIGN: Case series study. METHODS: We studied 5 ROP neonates either during sleep or under sedation both before and after photocoagulation, and evaluated 8 eyes in which the circulation could be measured three times consecutively...
September 20, 2017: Japanese Journal of Ophthalmology
https://www.readbyqxmd.com/read/28932777/dataset-on-the-associations-between-sleep-quality-duration-and-cognitive-performance-in-cognitively-healthy-older-adults
#9
A Tsapanou, Y Gu, D M O'Shea, M Yannakoulia, M H Kosmidis, E Dardiotis, G Hadjigeorgiou, P Sakka, Y Stern, N Scarmeas
In the present data, we provide the details of the cross-sectional study examining the associations between sleep quality/sleep duration and cognitive performance. Data are from the Hellenic Longitudinal Investigation of Aging and Diet (HELIAD). A total of 1484 older adults (65 y.o. or older) took part in the study. Sleep measurements were drawn from the sleep scale of the Medical Outcomes Study (MOS). Cognition was used as a z-score drawn by different tests. The domains examined were: executive function, visuo-spatial ability, language, attention- speed of processing, as well as the composite z-score of all the cognitive domains (including memory)...
October 2017: Data in Brief
https://www.readbyqxmd.com/read/28932553/the-relationship-between-apnoea-hypopnoea-index-and-gensini-score-in-patients-with-acute-myocardial-infarction-undergoing-emergency-primary-percutaneous-coronary-intervention
#10
Cai-Ping Zhu, Tao-Ping Li, Xiao Wang, Yu-Hua Zhao, Shi-Xi Zhou, Yan Fu, Yi-Wei Jiang, Xue-Ping Xiao
BACKGROUND: Sleep apnoea hypopnoea syndrome (SAHS) is characterised by repetitive nocturnal hypoxemia and has a high prevalence among patients with acute myocardial infarction (AMI). But there are few studies on patients with AMI undergoing emergency primary percutaneous coronary intervention (pPCI). In this study, we want to find the prevalence of SAHS among patients with AMI undergoing emergency pPCI and determine whether SAHS would worsen the condition among these people, and especially affect the damage degree of the coronary artery...
August 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28932301/melatonin-level-variations-with-different-behavioural-risk-factors-in-obese-female-patients
#11
Ana Malazonia, Tamar Zerekidze, Elen Giorgadze, Natia Chkheidze, Ketevan Asatiani
AIM: The role of behavioural factors and sleep duration and quality is important in the pathogenesis of obesity. The aim of our study was to evaluate the effects of behavioural risk factors on melatonin secretion in women. SUBJECTS AND METHODS: In total, 120 female patients were enrolled in the study and divided into two groups according to the body mass index. Detailed history, anthropometric measurements, urine and blood samples were evaluated for each patient...
August 15, 2017: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28932091/randomized-clinical-trial-comparing-fixed-time-split-dosing-and-split-dosing-of-oral-picosulfate-regimen-for-bowel-preparation
#12
Jae Hyuck Jun, Koon Hee Han, Jong Kyu Park, Hyun Il Seo, Young Don Kim, Sang Jin Lee, Baek Gyu Jun, Min Sik Hwang, Yoon Kyoo Park, Myeong Jong Kim, Gab Jin Cheon
AIM: To compare the efficacy of fixed-time split dose and split dose of an oral sodium picosulfate for bowel preparation. METHODS: This is study was prospective, randomized controlled study performed at a single Institution (2013-058). A total of 204 subjects were assigned to receive one of two sodium picosulfate regimens (i.e., fixed-time split or split) prior to colonoscopy. Main outcome measurements were bowel preparation quality and subject tolerability. RESULTS: There was no statistical difference between the fixed-time split dose regimen group and the split dose regimen group (Ottawa score mean 2...
August 28, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28931986/a-comparison-of-the-swallowing-function-and-quality-of-life-by-oral-intake-level-in-stroke-patients-with-dysphagia
#13
Deok Gi Hong, Doo Han Yoo
[Purpose] This study was conducted to compare the swallowing function and quality of life (QOL) in stroke patients with dysphagia by oral intake level. [Subjects and Methods] Seventy-nine stroke patients with dysphagia were enrolled. All subjects were evaluated by using the Swallowing Function Test (SFT) and the Swallowing Quality of Life (SWAL-QOL) questionnaire. The subjects were divided into two group based on the SFT score: oral intake (OI) and non-oral intake (NOI) groups. The SFT and SWAL-QOL scores were then compared between the groups...
September 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28931975/correlation-between-sleep-and-psychological-mood-states-in-female-wheelchair-basketball-players-on-a-japanese-national-team
#14
Kenji Tsunoda, Hirotaka Mutsuzaki, Kazushi Hotta, Yukiyo Shimizu, Naruki Kitano, Yasuyoshi Wadano
[Purpose] Although some studies suggest the importance of getting adequate sleep for enhancing mood, there is not yet sufficient evidence on the relationship between sleep and mood states in athletes, especially for athletes with physical disability. The purpose of this study is to reveal relationships between sleep and psychological mood states in female wheelchair basketball players. [Subjects and Methods] Seventeen female wheelchair basketball players (30.9 ± 9.4 years old) on a Japanese national team participated...
September 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28931660/predicting-epiglottic-collapse-in-patients-with-obstructive-sleep-apnoea
#15
Ali Azarbarzin, Melania Marques, Scott A Sands, Sara Op de Beeck, Pedro R Genta, Luigi Taranto-Montemurro, Camila M de Melo, Ludovico Messineo, Olivier M Vanderveken, David P White, Andrew Wellman
Obstructive sleep apnoea (OSA) is characterised by pharyngeal obstruction occurring at different sites. Endoscopic studies reveal that epiglottic collapse renders patients at higher risk of failed oral appliance therapy or accentuated collapse on continuous positive airway pressure. Diagnosing epiglottic collapse currently requires invasive studies (imaging and endoscopy). As an alternative, we propose that epiglottic collapse can be detected from the distinct airflow patterns it produces during sleep.23 OSA patients underwent natural sleep endoscopy...
September 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28929527/music-exposure-and-maturation-of-late-preterm-sleep-wake-cycles-a-randomized-crossover-trial
#16
Adia Stokes, Alexander G Agthe, Dina El Metwally
AIM: To determine the effect of music on sleep-wake cycle (SWC) patterns in late preterm neonates. METHODS: In a masked crossover study, infants between 32-36 6/7 weeks gestation were randomized to music exposure either during the first six or last six hours of a 12-hour observation period. SWC characteristics were determined by continuous amplitude integrated electroencephalography (aEEG) read by two coders masked to exposure sequence. Analysis was done in paired comparisons...
September 20, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28928050/predictors-of-onset-of-psychosis-in-patients-with-parkinson-s-disease-who-gets-it-early
#17
Abhishek Lenka, Lija George, Shyam Sundar Arumugham, Shantala Hegde, Venkateswara Reddy, Nitish Kamble, Ravi Yadav, Pramod Kumar Pal
INTRODUCTION: Psychosis is one of the common non-motor symptoms of PD, which substantially worsens the quality of life. Hence, it is important to identify factors that are associated with early onset of psychosis in PD. In order to identify those factors, the current study aims to compare various demographic and clinical features of PD patients with early and late onset psychosis. METHODOLOGY: In this prospective case-control study, 51 consecutive patients with PD having psychosis (PDP) were recruited...
September 14, 2017: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/28927491/effectiveness-of-intranasal-sodium-hyaluronate-in-mitigating-adverse-effects-of-nasal-continuous-positive-airway-pressure-therapy
#18
(no author information available yet)
BACKGROUND: Nasal continuous positive airway pressure (CPAP) in moderate-to-severe cases of obstructive sleep apnea cancause nasal discomfort and other undesirable problems. OBJECTIVE: The aim of our study was to test the effects of sodium hyaluronate on nasal problems that patients experienced in their daily lives, sleepiness, nasal resistance to airflow, nasal mucociliary clearance, changes in inflammatory markers, and compliance to CPAP in three groups of patients with obstructive sleep apnea syndrome on CPAP therapy...
September 19, 2017: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/28927417/automatic-sleep-staging-using-ear-eeg
#19
Kaare B Mikkelsen, David Bové Villadsen, Marit Otto, Preben Kidmose
BACKGROUND: Sleep and sleep quality assessment by means of sleep stage analysis is important for both scientific and clinical applications. Unfortunately, the presently preferred method, polysomnography (PSG), requires considerable expert assistance and significantly affects the sleep of the person under observation. A reliable, accurate and mobile alternative to the PSG would make sleep information much more readily available in a wide range of medical circumstances. NEW METHOD: Using an already proven method, ear-EEG, in which electrodes are placed inside the concha and ear canal, we measure cerebral activity and automatically score the sleep into up to five stages...
September 19, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/28927247/relationship-between-sleeping-difficulties-and-airway-symptoms-severity-with-the-health-related-quality-of-life-in-patients-with-gerd
#20
Claudio Andaloro, Mario Sati, Calogero Grillo, Caterina M Grillo, Ignazio LA Mantia
BACKGROUND: Gastroesophageal reflux disease (GERD) is a chronic disease highly associated with several pulmonary disease and sleep disorders leading to a negative impact on the quality of life. Aim of this study was to investigate the correlation between these disorders and the health-related quality of life. METHODS: Patients were recruited from the Department of Medical Sciences, Surgical and Advanced Technologies, GF Ingrassia, University of Catania, from October 2015 to May 2016...
December 2017: Minerva Gastroenterologica e Dietologica
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