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sleep deprivation and weight gain

Edson M de Oliveira, Bruna Visniauskas, Sergio Tufik, Monica L Andersen, Jair R Chagas, Ana Campa
Serum amyloid A (SAA) was recently associated with metabolic endotoxemia, obesity and insulin resistance. Concurrently, insufficient sleep adversely affects metabolic health and is an independent predisposing factor for obesity and insulin resistance. In this study we investigated whether sleep loss modulates SAA production. The serum SAA concentration increased in C57BL/6 mice subjected to sleep restriction (SR) for 15 days or to paradoxical sleep deprivation (PSD) for 72 h. Sleep restriction also induced the upregulation of Saa1...
March 21, 2017: Nutrients
Jennifer B Parrish, Jennifer A Teske
OBJECTIVE: Chronic partial sleep deprivation (SD) by environmental noise exposure increases weight gain and feeding in rodents, which contrasts weight loss after acute SD by physical methods. This study tested whether acute environmental noise exposure reduced sleep and its effect on weight gain, food intake, physical activity, and energy expenditure (EE). It was hypothesized that acute exposure would (1) increase weight gain and feeding and (2) reduce sleep, physical activity, and EE (total and individual components); and (3) behavioral changes would persist throughout recovery from SD...
January 2017: Obesity
H K Al Khatib, S V Harding, J Darzi, G K Pot
BACKGROUND/OBJECTIVES: It is unknown whether short sleep duration causatively contributes to weight gain. Studies investigating effects of partial sleep deprivation (PSD) on energy balance components report conflicting findings. Our objective was to conduct a systematic review and meta-analysis of human intervention studies assessing the effects of PSD on energy intake (EI) and energy expenditure (EE). SUBJECTS/METHODS: EMBASE, Medline, Cochrane CENTRAL, Web of Science and Scopus were searched...
November 2, 2016: European Journal of Clinical Nutrition
Xiaowen Xu, Liang Wang, Yan Zhang, Tianjiao Su, Liying Chen, Yan Zhang, Weifeng Ma, Yuanyuan Xie, Tiantian Wang, Fan Yang, Li He, Wenjiao Wang, Xuemei Fu, Hongxia Hao, Yuanzheng Ma
Epidemiological studies have shown that chronic sleep disturbances resulted in metabolic disorders. The purpose of this study was to assess the relationship between chronic sleep deprivation (CSD) and the glucose homeostasis in rats. Twenty-four rats were randomly divided into CSD group and control (CON) group. The CSD rats were intervened by a modified multiple platform method (MMPM) to establish an animal model of chronic sleep disturbances. After 3-month intervention, all rats were subjected to an intraperitoneal glucose tolerance test (IPGTT) and an insulin tolerance test (ITT), and the body weight, aspartate aminotransferase (AST), alanine aminotransferase (ALT), creatinine, lipid profile group, and homeostasis model assessment-IR (HOMA-IR) were measured...
2016: Sleep and Biological Rhythms
Irena Rot, Richard J Wassersug, Lauren M Walker
BACKGROUND: Androgen deprivation therapy (ADT) side effects are numerous and negatively impact prostate cancer patients' quality of life. There is considerable discrepancy though among Canadian urologists regarding what ADT side effects and side effect management strategies. Little is known about global differences in ADT patient education. METHODS: International respondents were recruited via online posting and at an international urology conference. Hypotheses suggest that economic and cultural differences influence patient education practices; therefore, international respondents were divided into 3 categories (high, medium, and low gross domestic product)...
April 2016: Translational Andrology and Urology
Sara Edwards
No abstract text is available yet for this article.
2014: Journal of Nursing Doctoral Students Scholarship
Emiko Anegawa, Nozomu Kotorii, Yuji Ishimaru, Masashi Okuro, Noriaki Sakai, Seiji Nishino
The purpose of this study is to clarify the effects of chronic powder diet feeding on sleep patterns and other physiological/anatomical changes in mice. C57BL/6 male mice were divided into two groups from weaning: a group fed with solid food (SD) and a group fed with powder food (PD), and sleep and physiological and anatomical changes were compared between the groups. PD exhibited less cranial bone structure development and a significant weight gain. Furthermore, these PD mice showed reduced number of neurogenesis in the hippocampus...
2015: PloS One
Jean-Philippe Chaput
Chronic lack of sleep (called "sleep deprivation") is common in modern societies with 24/7 availability of commodities. Accumulating evidence supports the role of reduced sleep as contributing to the current obesity epidemic in children and youth. Longitudinal studies have consistently shown that short sleep duration is associated with weight gain and the development of obesity. Recent experimental studies have reported that sleep restriction leads to weight gain in humans. Increased food intake appears to be the main mechanism by which insufficient sleep results in weight gain...
March 2016: Eating and Weight Disorders: EWD
Suzan Gunduz, Hatice Kosger, Secil Aldemir, Banu Akcal, Hatice Tevrizci, Deniz Hizli, Huseyin Tugrul Celik
BACKGROUND: Disturbed sleep is a significant health issue for pregnant women. Inadequate vitamin D intake is common among pregnant women and can affect many bodily systems. The purpose of this cross-sectional study was to test the hypothesis that serum vitamin D levels are low in pregnant women who have poor sleep quality in their last trimester. METHODS: We enrolled 92 pregnant women who were admitted to the Maternity Clinic of Turgut Ozal University (Ankara, Turkey) in their last trimester...
January 2016: Journal of the Chinese Medical Association: JCMA
Isaac J Perron, Allan I Pack, Sigrid Veasey
STUDY OBJECTIVES: Excessive daytime sleepiness commonly affects obese people, even in those without sleep apnea, yet its causes remain uncertain. We sought to determine whether acute dietary changes could induce or rescue wake impairments independent of body weight. DESIGN: We implemented a novel feeding paradigm that generates two groups of mice with equal body weight but opposing energetic balance. Two subsets of mice consuming either regular chow (RC) or high-fat diet (HFD) for 8 w were switched to the opposite diet for 1 w...
December 1, 2015: Sleep
James A Horne
Rapid eye movement (REM) sleep shares many underlying mechanisms with wakefulness, to a much greater extent than does non-REM, especially those relating to feeding behaviours, appetite, curiosity, exploratory (locomotor) activities, as well as aspects of emotions, particularly 'fear extinction'. REM is most evident in infancy, thereafter declining in what seems to be a dispensable manner that largely reciprocates increasing wakefulness. However, human adults retain more REM than do other mammals, where for us it is most abundant during our usual final REM period (fREMP) of the night, nearing wakefulness...
August 2015: Sleep Medicine
Debra L Barton, Patricia A Ganz
By 2022, the number of survivors is expected to grow to nearly 18 million. Therefore, addressing acute and chronic negative sequelae of a cancer diagnosis and its treatments becomes a health imperative. For women with a history of breast cancer, one of the common goals of treatment and prevention of recurrence is to reduce circulating concentrations of estradiol, especially in women with hormone receptor positive breast cancer. Hormone deprivation after a diagnosis of breast cancer impacts physiological targets other than in the breast tissue and can result in unwanted side effects, all of which can negatively impact quality of life and function and cause distress...
2015: Advances in Experimental Medicine and Biology
(no author information available yet)
No abstract text is available yet for this article.
October 2014: Mayo Clinic Health Letter
Astrid Merkx, Marlein Ausems, Luc Budé, Raymond de Vries, Marianne J Nieuwenhuijze
OBJECTIVE: to explore gestational weight gain in healthy women in relation to pre-pregnancy Body Mass Index, diet and physical activity. DESIGN: a cross-sectional survey was conducted among 455 healthy pregnant women of all gestational ages receiving antenatal care from an independent midwife in the Netherlands. Weight gain was assessed using the Institute of Medicine (IOM) guidelines and classified as below, within, or above the guidelines. A multinomial regression analysis was performed with weight gain classifications as the dependent variable (within IOM-guidelines as reference)...
July 2015: Midwifery
Stacey L Simon, Julie Field, Lauren E Miller, Mark DiFrancesco, Dean W Beebe
STUDY OBJECTIVE: Examine the effect of experimental sleep restriction (SR) on adolescents' subjective hunger and perceived appeal of sweet/dessert foods versus other foods. A secondary goal was to replicate previous findings on the effects of SR on dietary intake. DESIGN: Randomized cross-over sleep restriction-extension paradigm. SETTING: Sleep was obtained and monitored at home. Outcome measures were gathered during office visits. PARTICIPANTS: 31 typically-developing adolescents aged 14-17 years...
2015: PloS One
Sean W Cain, Ashleigh J Filtness, Craig L Phillips, Clare Anderson
OBJECTIVES: Shift workers are prone to obesity and associated co-morbidities such as diabetes and cardiovascular disease. Sleep restriction associated with shift work results in dramatic endocrine and metabolic effects that predispose shift workers to these adverse health consequences. While sleep restriction has been associated with increased caloric intake, food preference may also play a key role in weight gain associated with shift work. This study examined the impact of an overnight simulated night shift on food preference...
May 1, 2015: Scandinavian Journal of Work, Environment & Health
Aalim M Weljie, Peter Meerlo, Namni Goel, Arjun Sengupta, Matthew S Kayser, Ted Abel, Morris J Birnbaum, David F Dinges, Amita Sehgal
Sleep is an essential biological process that is thought to have a critical role in metabolic regulation. In humans, reduced sleep duration has been associated with risk for metabolic disorders, including weight gain, diabetes, obesity, and cardiovascular disease. However, our understanding of the molecular mechanisms underlying effects of sleep loss is only in its nascent stages. In this study we used rat and human models to simulate modern-day conditions of restricted sleep and addressed cross-species consequences via comprehensive metabolite profiling...
February 24, 2015: Proceedings of the National Academy of Sciences of the United States of America
Zhuo Fang, Andrea M Spaeth, Ning Ma, Senhua Zhu, Siyuan Hu, Namni Goel, John A Detre, David F Dinges, Hengyi Rao
Although insufficient sleep is a well-recognized risk factor for overeating and weight gain, the neural mechanisms underlying increased caloric (particularly fat) intake after sleep deprivation remain unclear. Here we used resting-state functional magnetic resonance imaging and examined brain connectivity changes associated with macronutrient intake after one night of total sleep deprivation (TSD). Compared to the day following baseline sleep, healthy adults consumed a greater percentage of calories from fat and a lower percentage of calories from carbohydrates during the day following TSD...
February 3, 2015: Scientific Reports
L McDonald, J Wardle, C H Llewellyn, L Johnson, C H M van Jaarsveld, H Syrad, A Fisher
BACKGROUND: Shorter sleep is a risk factor for weight gain in young children. Experimental studies show that sleep deprivation is associated with higher nighttime energy intake, but no studies have examined the patterning of energy intake in relation to nighttime sleep duration in young children. OBJECTIVES: The objectives of the study were to test the hypothesis that shorter-sleeping children would show higher nighttime energy intake and to examine whether the additional calories were from drinks, snacks or meals...
December 2015: Pediatric Obesity
Edson Mendes de Oliveira, Bruna Visniauskas, Silvana Sandri, Silene Migliorini, Monica Levy Andersen, Sergio Tufik, Ricardo Ambrósio Fock, Jair Ribeiro Chagas, Ana Campa
OBJECTIVE: Epidemiological studies show the association of sleep restriction (SR) with obesity and insulin resistance. Experimental studies are limited to the concurrent or short-term effects of SR. Here, we examined the late effects of SR regarding weight gain and metabolic alterations induced by a high-fat diet (HFD). METHODS: C57BL/6 mice were subjected to a multiple platform method of SR for 15 days, 21 h daily, followed by 6 weeks of a 30% HFD. RESULTS: Just after SR, serum insulin and resistin concentrations were increased and glycerol content decreased...
February 2015: Obesity
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