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https://www.readbyqxmd.com/read/27924279/accelerating-in-vitro-studies-on-circadian-clock-systems-using-an-automated-sampling-device
#1
Yoshihiko Furuike, Jun Abe, Atsushi Mukaiyama, Shuji Akiyama
KaiC, a core protein of the cyanobacterial circadian clock, is rhythmically autophosphorylated and autodephosphorylated with a period of approximately 24 h in the presence of two other Kai proteins, KaiA and KaiB. In vitro experiments to investigate the KaiC phosphorylation cycle consume considerable time and effort. To automate the fractionation, quantification, and evaluation steps, we developed a suite consisting of an automated sampling device equipped with an 8-channel temperature controller and accompanying analysis software...
2016: Biophysics and Physicobiology
https://www.readbyqxmd.com/read/27922562/operation-smile-and-the-guwahati-comprehensive-cleft-care-center-multidisciplinary-global-activism-in-plastic-surgery
#2
Chad Allen Purnell
Participation in a medical mission in an underserved area is both a challenging and deeply satisfying experience. The global burden of cleft lip and palate is significant, and as plastic surgery providers we are all empowered to help these patients. Surgery for cleft lip and palate is life changing for patients, and the privilege of participating in a mission can be life altering for the providers as well. The Comprehensive Cleft Care Center in Guwahati, India, is a prime example of multidisciplinary collaboration resulting in excellent care in the developing world...
October 2016: Plastic Surgical Nursing
https://www.readbyqxmd.com/read/27916313/influence-of-the-flap-on-outcomes-in-corneal-refractive-surgery-with-femtosecond-laser-smile-vs-flex
#3
J L Alió, M El Bahrawy, A Angelov, D Ortiz, P Yébana
OBJECTIVE: To investigate the influence of creating a flap on the postoperative optical quality of the cornea in terms of predicted corneal curvature and Seidel aberrations after 2 modalities of femtosecond assisted corneal lenticule extraction laser for the correction of myopia and myopic astigmatism: The flapless procedure small incision lenticular extraction (SMILE) and the flap-based femtosecond lenticular extraction (FLEx). METHODS: The study is a prospective consecutive non-randomised comparative interventional case series including 64 eyes with myopic or myopic astigmatism refractive errors...
December 1, 2016: Archivos de la Sociedad Española de Oftalmología
https://www.readbyqxmd.com/read/27911101/in-vivo-and-ex-vivo-evaluation-of-inflammation-and-apoptosis-induced-after-smile-procedures-for-different-refractive-error-range
#4
Leonardo Mastropasqua, Roberta Calienno, Claudia Curcio, Rodolfo Mastropasqua, Mario Nubile, Niccolò Salgari, Manuela Lanzini
PURPOSE: To detect corneal inflammation and apoptosis induced after small incision lenticule extraction (SMILE) at different refractive corrections for moderate to high values of myopia. METHODS: Fifty patients (50 eyes) suffering from medium to high myopia (spherical equivalent refraction from -3.75 to -10.00 diopters (D) with refractive astigmatism under -0.75 D) underwent SMILE in order to correct myopic error. In vivo evaluation was done by corneal confocal microscopy (IVCM) and ex vivo by immunohistochemistry...
December 2, 2016: Current Eye Research
https://www.readbyqxmd.com/read/27901230/esthetic-perception-of-orthodontic-appliances-by-brazilian-children-and-adolescents
#5
Deise Caldas Kuhlman, Tatiana Araújo de Lima, Candice Belchior Duplat, Jonas Capelli
Objective: The objective of this present study was to understand how children and adolescents perceive esthetic attractiveness of a variety of orthodontic appliances. It also analyzed preferences according to patients' age, sex and socioeconomic status. Methods: A photograph album consisting of eight photographs of different orthodontic appliances and clear tray aligners placed in a consenting adult with pleasing smile was used. A sample of children or adolescents aged between 8 and 17 years old (n = 276) was asked to rate each image for its attractiveness on a visual analog scale...
September 2016: Dental Press Journal of Orthodontics
https://www.readbyqxmd.com/read/27900467/what-makes-a-smiling-face-look-happy-visual-saliency-distinctiveness-and-affect
#6
Manuel G Calvo, Aida Gutiérrez-García, Mario Del Líbano
We investigated the relative contribution of (a) perceptual (eyes and mouth visual saliency), (b) conceptual or categorical (eye expression distinctiveness), and (c) affective (rated valence and arousal) factors, and (d) specific morphological facial features (Action Units; AUs), to the recognition of facial happiness. The face stimuli conveyed truly happy expressions with a smiling mouth and happy eyes, or blended expressions with a smile but non-happy eyes (neutral, sad, fearful, disgusted, surprised, or angry)...
November 29, 2016: Psychological Research
https://www.readbyqxmd.com/read/27896197/a-refined-technique-for-management-of-nasal-flaring-the-quest-for-the-holy-grail-of-alar-base-modification
#7
Kapil S Agrawal, Mansi Pabari, Raghav Shrotriya
"A smile is happiness you'll find right under your nose"- Tom Wilson. This quote holds true just for patients, not for surgeons. The correction of the nose always poses a challenge to the cosmetic surgeon. Deformities of the external and internal nose may be congenital or acquired and may be secondary to soft tissue and/or osseo-cartilaginous abnormalities, leading to aesthetic and/or functional consequences. Alar flare poses a common problem, sometimes alone and sometimes in conjunction with other external deformities...
November 2016: Archives of Plastic Surgery
https://www.readbyqxmd.com/read/27893524/visual-outcomes-after-smile-lasek-and-lasek-combined-with-corneal-collagen-cross-linking-for-high-myopic-correction
#8
Sangyoon Hyun, Seongjun Lee, Jae-Hyung Kim
PURPOSE: To compare the visual and refractive outcomes of small-incision lenticule extraction (SMILE), laser-assisted subepithelial keratomileusis (LASEK), and LASEK combined with corneal collagen cross-linking (LASEK-CXL) surgery for high-degree myopia. METHODS: Medical records of patients with spherical equivalent (SE) greater than -6.00 diopters (D) treated with SMILE, LASEK, and LASEK-CXL were reviewed. Uncorrected distance visual acuity (UCVA), SE, and corneal haze were followed up in the 3 groups for 6 months...
November 23, 2016: Cornea
https://www.readbyqxmd.com/read/27891819/autism-and-emotional-face-viewing
#9
Jakob Åsberg Johnels, Daniel Hovey, Nicole Zürcher, Loyse Hippolyte, Eric Lemonnier, Christopher Gillberg, Nouchine Hadjikhani
Atypical patterns of face-scanning in individuals with autism spectrum disorder (ASD) may contribute to difficulties in social interactions, but there is little agreement regarding what exactly characterizes face-viewing in ASD. In addition, little research has examined how face-viewing is modulated by the emotional expression of the stimuli, in individuals with or without ASD. We used eye-tracking to explore viewing patterns during perception of dynamic emotional facial expressions in relatively large groups of individuals with (n = 57) and without ASD (n = 58) and examined diagnostic- and age-related effects, after subgrouping children and adolescents (≤18 years), on the one hand, and adults (>18 years), on the other...
November 28, 2016: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/27891478/customized-modified-haas-palatal-expansion-in-mixed-dentition-a-case-report
#10
Ziauddin Mohammad, Sampath Reddy Cheruku, Sarada Penmetcha, Srinivas Namineni, Phani Himaja Devi Vaaka
The dental arch perimeter and transpalatal width are the most significant arch dimensions in the developing individuals. Its management during the primary, mixed and early permanent dentition are greatly important for the normal development of the dental arches and significantly improve the occlusion in adulthood. Malocclusion is a constant source of threat to the facial appearance. Severe anterior crowding and narrow maxillary arches adversely affect the smile, facial profile and consequently patient becomes handicapped socially as well as psychologically...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27885862/an-automated-curation-procedure-for-addressing-chemical-errors-and-inconsistencies-in-public-datasets-used-in-qsar-modelling
#11
K Mansouri, C M Grulke, A M Richard, R S Judson, A J Williams
The increasing availability of large collections of chemical structures and associated experimental data provides an opportunity to build robust QSAR models for applications in different fields. One common concern is the quality of both the chemical structure information and associated experimental data. Here we describe the development of an automated KNIME workflow to curate and correct errors in the structure and identity of chemicals using the publicly available PHYSPROP physicochemical properties and environmental fate datasets...
November 2016: SAR and QSAR in Environmental Research
https://www.readbyqxmd.com/read/27882653/synkinesis-in-bell-s-palsy-in-a-randomised-controlled-trial
#12
N Bylund, D Jensson, S Enghag, T Berg, Elin Marsk, Malou Hultcrantz, N Hadziosmanovic, A Rodriguez-Lorenzo, L Jonsson
OBJECTIVES: To study the development of synkinesis in Bell's palsy. Frequency, severity, gender aspects and predictors were analysed. DESIGN: Data from the randomised controlled Scandinavian Bell's palsy trial including 829 patients. MAIN OUTCOME MEASURES: Frequency and severity of synkinesis at 12 months were the main outcome measures. Mean Sunnybrook synkinesis scores, voluntary movement scores and composite scores between 6 and 12 months were compared...
November 24, 2016: Clinical Otolaryngology
https://www.readbyqxmd.com/read/27881323/celebrity-smile-esthetics-assessment-smile-angulation
#13
Vasiliki P Koidou, Stephen F Rosenstiel, Robert G Rashid
STATEMENT OF PROBLEM: Whether deviations in the angulation discrepancy between the intercanine and interpupillary line significantly affect attractiveness is unknown. PURPOSE: The purpose of this prospective study was to quantify dental and facial esthetics to determine whether smile angulation discrepancies in individuals identified as having attractive smiles are smaller than those in the average population. MATERIAL AND METHODS: An Internet search for "best smile" and "celebrity" identified 108 celebrities (Test group)...
October 27, 2016: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/27881322/layperson-s-preference-regarding-orientation-of-the-transverse-occlusal-plane-and-commissure-line-from-the-frontal-perspective
#14
Bruno Pereira Silva, Emilio Jiménez-Castellanos, Sivan Finkel, Inmaculada Redondo Macias, Stephen J Chu
STATEMENT OF PROBLEM: Facial asymmetries in features such as lip commissure and interpupillary plane canting have been described as common conditions affecting smile esthetics. When presented with these asymmetries, the clinician must choose the reference line with which to orient the transverse occlusal plane of the planned dental restorations. PURPOSE: The purpose of the online survey described in this study was to determine lay preferences regarding the transverse occlusal plane orientation in faces that display a cant of the commissure line viewed from the frontal perspective...
October 27, 2016: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/27878740/brief-report-a-comparison-of-the-preference-for-viewing-social-and-non-social-movies-in-typical-and-autistic-adolescents
#15
Indu Dubey, Danielle Ropar, Antonia F de C Hamilton
The recently proposed Social Motivation theory (Chevallier et al., Trends in cognitive sciences 16(4):231-239, 2012) suggests that social difficulties in Autism Spectrum Condition (ASC) might be caused by a difference in the motivation to engage with other people. Here we compared adolescents with (N = 31) and without (N = 37) ASC on the Choose-a-Movie paradigm that measures the social seeking. The results showed a preference for viewing objects over smiling faces in ASC, which is in line with the theory of low social motivation...
November 23, 2016: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/27873423/the-power-of-the-pen-how-to-make-physicians-more-friendly-and-patients-more-attractive
#16
Nurith Epstein, Thomas Brendel, Inga Hege, Diana L Ouellette, Ralf Schmidmaier, Jan Kiesewetter
CONTEXT: Studies have shown that patients' subjective perceptions of physicians' competence and friendliness are relevant aspects of a successful treatment, influencing patients' well-being and trust in the physician. Psychological research has repeatedly shown that unconsciously contracting muscles that are usually used to smile can intensify and even elicit positive feelings (known as facial feedback). Empirical evidence also suggests that a smiling person is favourably judged by others with respect to attractiveness and trustworthiness...
December 2016: Medical Education
https://www.readbyqxmd.com/read/27872548/perception-of-altered-smile-esthetics-among-moroccan-professionals-and-lay-people
#17
L Ousehal, H Aghoutan, S Chemlali, I Filali Anssari, N Talic
OBJECTIVE: To evaluate and compare the impact of altered smile characteristics on the perception of smile esthetics between Moroccan dentists and lay people. MATERIALS AND METHODS: Thirty-four digital smile photographs displaying alterations in crown length and width, lateral incisor gingival margin position, gingival exposition, midline diastema, and upper midline deviation were presented to a sample of 30 dentists and 30 lay people. The ratings were assessed with a visual analog scale...
October 2016: Saudi Dental Journal
https://www.readbyqxmd.com/read/27871700/laypeople-s-perceptions-of-frontal-smile-esthetics-a-systematic-review
#18
Simone Parrini, Gabriele Rossini, Tommaso Castroflorio, Arturo Fortini, Andrea Deregibus, Cesare Debernardi
INTRODUCTION: The emphasis on dental esthetics has increased in recent years. There are, however, differences in esthetic perceptions among professional and lay groups. The aim of this comprehensive review was to update previous reviews and answer the following research question: Can lay thresholds for acceptance of smile esthetic anomalies be defined? METHODS: A systematic search in the medical literature (PubMed, PMC, NLM, Embase, Cochrane Central Register of Controlled Clinical trials, Web of Knowledge, Scopus, Google Scholar, and LILACs) was performed to identify all peer-reviewed articles reporting data regarding evaluations of laypeople's perceptions of dental esthetic factors...
November 2016: American Journal of Orthodontics and Dentofacial Orthopedics
https://www.readbyqxmd.com/read/27866371/sparse-multidimensional-iterative-lineshape-enhanced-smile-reconstruction-of-both-non-uniformly-sampled-and-conventional-nmr-data
#19
Jinfa Ying, Frank Delaglio, Dennis A Torchia, Ad Bax
Implementation of a new algorithm, SMILE, is described for reconstruction of non-uniformly sampled two-, three- and four-dimensional NMR data, which takes advantage of the known phases of the NMR spectrum and the exponential decay of underlying time domain signals. The method is very robust with respect to the chosen sampling protocol and, in its default mode, also extends the truncated time domain signals by a modest amount of non-sampled zeros. SMILE can likewise be used to extend conventional uniformly sampled data, as an effective multidimensional alternative to linear prediction...
November 19, 2016: Journal of Biomolecular NMR
https://www.readbyqxmd.com/read/27863469/changes-in-intraocular-pressure-values-measured-with-noncontact-tonometer-nct-ocular-response-analyzer-ora-and-corvis-scheimpflug-technology-tonometer-cst-in-the-early-phase-after-small-incision-lenticule-extraction-smile
#20
Yang Shen, Xiangjian Su, Xiu Liu, Huamao Miao, Xuejun Fang, Xingtao Zhou
BACKGROUND: Corneal biomechanical properties are always compromised after corneal refractive surgeries thus leading to underestimated intraocular pressure (IOP) that complicates the management of IOP. We investigated the changes in postoperative baseline of IOP values measured with noncontact tonometer (NCT), ocular response analyzer (ORA) and corvis scheimpflug technology (CST) in the early phase after small incision lenticule extraction (SMILE). METHODS: Twenty-two eyes (-6...
November 18, 2016: BMC Ophthalmology
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