Read by QxMD icon Read


Ivan Yu Chernyshov, Philip V Toukach
Motivation: Glycans and glycoconjugates are usually recorded in dedicated databases in residue-based notations. Only a few of them can be converted into chemical (atom-based) formats highly demanded in conformational and biochemical studies. In this work, we present a tool for translation from a residue-based glycan notation to SMILES. Results: The REStLESS algorithm for translation from the CSDB Linear notation to SMILES was developed. REStLESS stands for ResiduEs as Smiles and LinkagEs as SmartS, where SMARTS reaction expressions are used to merge pre-encoded residues into a molecule...
March 14, 2018: Bioinformatics
Edward Snelson, Shammi Ramlakhan
OBJECTIVE: In an attempt to improve the diagnosis of sepsis in children, diagnostic aids have concentrated on clinical features that suggest that sepsis is present. Clinicians need to be able to clinically rule out sepsis as well as rule it in. Little is known about which features are consistent with wellness and/or absence of sepsis. Guidelines are therefore likely to improve sensitivity without preserving specificity. We aimed to gather expert opinion on which (if any) features would make clinicians consider a child to be unlikely to have sepsis...
March 15, 2018: Archives of Disease in Childhood
E N Eskina, K K Davtyan
Presently ReLEx Smile as a method of vision correction in refractive surgery is becoming increasingly popular in Russia and abroad. PURPOSE: to develop an algorithm for planning the surgery and choosing its parameters, and to assess the efficacy, safety and predictability of the results in the 6-month follow-up period. MATERIAL AND METHODS: The study involved 80 patients (159 eyes) with myopia of various degrees with a mean age of 33±6 years (25 to 44 years old)...
2018: Vestnik Oftalmologii
Mehdi Shajari, Emanuel Wanner, Vladimir Rusev, Shervin Mir Mohi Sefat, Wolfgang J Mayer, Thomas Kohnen, Siegfried Priglinger, Daniel Kook
PURPOSE: To compare corneal densitometry values after Femtosecond Laser-Assisted In Situ Keratomileusis (Fs-LASIK) and Small Incision Lenticule Extraction (SMILE) using Scheimpflug Imaging. METHODS: Our retrospective clinical trial included a total of 146 eyes where 57 eyes underwent Fs-LASIK and 89 eyes underwent SMILE. Examinations with a Pentacam Scheimpflug device (Oculus, Wetzlar, Germany) were performed before surgery, 1 week, 1 month, 3 months, 6 months, and 1 year after surgery...
March 14, 2018: Current Eye Research
Lixin Cheng, Pengfei Liu, Kwong-Sak Leung
Computational clustering methods help identify functional modules in protein-protein interaction (PPI) network, in which proteins participate in the same biological pathways or specific functions. Subcellular localisation is crucial for proteins to implement biological functions and each compartment accommodates specific portions of the protein interaction structure. However, the importance of protein subcellular localisation is often neglected in the studies of module identification. In this study, the authors propose a novel procedure, subcellular module identification with localisation expansion (SMILE), to identify super modules that consist of several subcellular modules performing specific biological functions among cell compartments...
April 2018: IET Systems Biology
Dauro Douglas Oliveira, Bruno Franco de Oliveira, Carolina Morsani Mordente, Gabriela Martins Godoy, Rodrigo Villamarim Soares, Paulo Isaías Seraidarian
The purpose of this paper is to present and discuss a simple and low-cost clinical approach to correct an asymmetric skeletal Class III combined to an extensive dental open bite that significantly compromised the occlusal function and smile aesthetics of an adult male patient. The patient did not accept the idealistic surgical-orthodontic treatment option, neither the use of temporary anchorage devices to facilitate the camouflage of the asymmetrical skeletal Class III/open bite. Therefore, a very simple and inexpensive biomechanical approach using sliding jigs in the mandibular arch was implemented as the compensatory treatment of the malocclusion...
March 12, 2018: Journal of Orthodontics
Marcel Riehle, Tania M Lincoln
People with schizophrenia show marked reductions in their emotional expressiveness, generally known as blunted affect. In this study, we tested whether interaction partners would evaluate community-dwelling participants with schizophrenia less favorably than healthy controls and whether this difference would be explained by reduced smiling behavior related to schizophrenia. We also tested whether deficient affect recognition would predict reduced smiling. We created 3 study groups, consisting of 28 participants each, participants with schizophrenia (SZ), healthy controls (HC), and naive healthy interaction partners (IP)...
February 2018: Journal of Abnormal Psychology
Ikhyun Jun, David Sung Yong Kang, Dan Z Reinstein, Samuel Arba-Mosquera, Timothy J Archer, Kyoung Yul Seo, Tae-Im Kim
PURPOSE: To comparatively investigate the clinical outcomes, vector parameters, and corneal aberrations of small incision lenticule extraction (SMILE) with a triple centration technique and corneal wavefront-guided transepithelial photorefractive keratectomy (PRK) for the correction of high astigmatism. METHODS: This retrospective, comparative case series study included 89 eyes (89 patients) that received treatment for myopia with high astigmatism (≥ 2.50 diopters) using SMILE with a triple centration technique (SMILE group; 45 eyes) and corneal wavefront-guided transepithelial PRK (transepithelial PRK group; 44 eyes)...
March 1, 2018: Journal of Refractive Surgery
(no author information available yet)
No abstract text is available yet for this article.
March 9, 2018: British Dental Journal
Hui Guo, Xiao-Hui Zhang, Jun Liang, Wen-Jing Yan
The smile is a frequently expressed facial expression that typically conveys a positive emotional state and friendly intent. However, human beings have also learned how to fake smiles, typically by controlling the mouth to provide a genuine-looking expression. This is often accompanied by inaccuracies that can allow others to determine that the smile is false. Mouth movement is one of the most striking features of the smile, yet our understanding of its dynamic elements is still limited. The present study analyzes the dynamic features of lip corners, and considers how they differ between genuine and posed smiles...
2018: Frontiers in Psychology
Alireza Torabi, Babak Najafi, Howard J Drew, Emil G Cappetta
Improvement of smile esthetics is a major goal of modern dentistry. Various treatment modalities have been proposed to correct excessive gingival display (EGD), depending on the identified etiologies. This study reports on the clinical and patient-centered outcomes of a novel lip repositioning technique with vestibular shallowing approach in the treatment of three types of EGD with varying etiologies. Periosteal fenestration with cicatrization (scarification) was performed at the mucogingival junction to ensure the stability of esthetic outcomes...
March 7, 2018: International Journal of Periodontics & Restorative Dentistry
Flàvia Pardo Salata Nahsan, Maria Janete Oliveira Reis, Luciana Fàvaro Francisconi-Dos-Rios, Luciana Vasconcelos Leão, Luiz Renato Paranhos
Products for tooth whitening (or tooth color maintenance) that improve smile esthetics have become increasingly popular due to their easy accessibility and low cost. This in vitro study assessed the effect of whitening mouthwash on bovine tooth color. Forty-eight bovine teeth were divided into 3 immersion groups: SL, artificial saliva (control); CLW, Colgate Luminous White; and OBW, Oral-B 3D White. After prophylaxis with pumice, the initial color was measured using the CIE L*a*b* system. Teeth were immersed in the solutions for 2 minutes, 3 times per day, for 30 days...
March 2018: General Dentistry
Chihiro Tanikawa, Kenji Takada
OBJECTIVES: To evaluate the test-retest reliability of three types of facial expression tasks using three-dimensional (3D) facial topography. MATERIALS AND METHODS: Twelve adult volunteers were enrolled in this study. They were instructed to perform three different facial expression tasks: rest posture, posed smile, and maximum effort smile. Each task was recorded using a 3D image-capturing device on two separate occasions with an interval of 1 week between sessions...
March 6, 2018: Angle Orthodontist
Peter Hsien-Li Peng, Jui-Hui Peng
INTRODUCTION: The tear trough deformity is commonly requested for correction, most often by filler injections. However, the tear trough remains difficult to treat due to its complex anatomy, a variety of other concurrent deformities, and the high risk of complications. OBJECTIVES: To create a standardized categorization, evaluation, and treatment protocol for the management of tear troughs with fillers. METHODS: (1) Patient deformity profiles are determined using three categories of traits: A (Atrophy), B (Bulging), L (Laxity)...
March 5, 2018: Journal of Cosmetic Dermatology
Monica Mele, Pietro Felice, Praveen Sharma, Claudio Mazzotti, Pietro Bellone, Giovanni Zucchelli
Altered passive eruption is described as a condition in which the relationship between teeth, alveolar bone and soft tissues creates an excessive display of gingiva, commonly known as a 'gummy smile'. While there are authors who consider altered passive eruption to be a risk to periodontal health, its impact is greatest in terms of oral esthetics. The aim of periodontal management in such cases is not only to improve patient esthetics but also to restore periodontal health by re-establishing the normal relationship between the gingival margin, alveolar bone crest and cemento-enamel junction...
March 4, 2018: Periodontology 2000
Thaís Teixeira de Paiva, Ricardo Martins Machado, Alexandre Trindade Motta, Claudia Trindade Mattos
INTRODUCTION: Our objectives were to verify the impact of alterations in the vertical position of the maxillary canines in smile esthetic perceptions and to determine whether exposure of the gingival margins directly affects laypersons' and orthodontists' perceptions. METHODS: A smile photograph of a male subject showing gingival zeniths was selected, and the canine vertical positions were symmetrically modified in increments of 0.5 mm, creating 4 new images varying from 1...
March 2018: American Journal of Orthodontics and Dentofacial Orthopedics
Donald L Chi, Peter Milgrom, Jane Gillette
Purpose: The purpose of this study was to use qualitative methods to describe the key lessons learned during the stakeholder engagement stage of planning a randomized clinical trial comparing outcomes of silver diamine fluoride (SDF) as an alternative to pit-and-fissure sealants in a school-based delivery system. Methods: Eighteen caregivers and community-based stakeholders with involvement in the school-based sealant program Sealants for Smiles from the state of Montana, were recruited for this qualitative study...
February 2018: Journal of Dental Hygiene: JDH
Sven Söderkvist, Kajsa Ohlén, Ulf Dimberg
The facial feedback hypothesis states that facial actions modulate subjective experiences of emotion. Using the voluntary facial action technique, in which the participants react with instruction induced smiles and frowns when exposed to positive and negative emotional pictures and then rate the pleasantness of these stimuli, four questions were addressed in the present study. The results in Experiment 1 demonstrated a feedback effect because participants experienced the stimuli as more pleasant during smiling as compared to when frowning...
2018: Journal of Nonverbal Behavior
Corine Dijk, Agneta H Fischer, Nexhmedin Morina, Charlotte van Eeuwijk, Gerben A van Kleef
Socially anxiety may be related to a different pattern of facial mimicry and contagion of others' emotions. We report two studies in which participants with different levels of social anxiety reacted to others' emotional displays, either shown on a computer screen (Study 1) or in an actual social interaction (Study 2). Study 1 examined facial mimicry and emotional contagion in response to displays of happiness, anger, fear, and contempt. Participants mimicked negative and positive emotions to some extent, but we found no relation between mimicry and the social anxiety level of the participants...
2018: Journal of Nonverbal Behavior
Jared D Martin, Heather C Abercrombie, Eva Gilboa-Schechtman, Paula M Niedenthal
When people are being evaluated, their whole body responds. Verbal feedback causes robust activation in the hypothalamic-pituitary-adrenal (HPA) axis. What about nonverbal evaluative feedback? Recent discoveries about the social functions of facial expression have documented three morphologically distinct smiles, which serve the functions of reinforcement, social smoothing, and social challenge. In the present study, participants saw instances of one of three smile types from an evaluator during a modified social stress test...
March 1, 2018: Scientific Reports
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"