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https://www.readbyqxmd.com/read/28331285/refraction-outcomes-after-suction-loss-during-small-incision-lenticule-extraction-smile
#1
Amr A Gab-Alla
PURPOSE: To evaluate refractive outcomes of two management approaches after suction loss during the small-incision lenticule extraction (SMILE) technique. PATIENTS AND METHODS: This retrospective and comparative study was conducted at the El-Gowhara Private Eye Center. It included 26 consecutive eyes of patients who experienced suction loss during the SMILE technique. Patients were divided into two groups by the technical difficulties in redocking: in group A (12 eyes) suction loss occurred after the posterior lenticular cut and the creation of side-cuts, then suction was reapplied, and the procedure was completed; in group B (14 eyes) suction loss occurred after the posterior lenticular cut and the creation of side-cuts, then the procedure was postponed for 24 hours and completed with the same parameters...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28327110/an-assessment-of-the-impacts-of-child-oral-health-in-indonesia-and-associations-with-self-esteem-school-performance-and-perceived-employability
#2
Diah Ayu Maharani, Melissa Adiatman, Anton Rahardjo, Girvan Burnside, Cynthia Pine
BACKGROUND: Previous surveys have indicated that a majority of Indonesian children have poor oral health. However, little detailed information is available on underlying causation and none that examine impacts of oral health on child self-esteem, school performance and perceived employability. The aim of this study was to determine levels of child oral health in primary school children in Indonesia, the prevalence of key causal factors; and, to determine relationships between oral health, self-esteem and school academic performance...
March 21, 2017: BMC Oral Health
https://www.readbyqxmd.com/read/28318639/enhancement-after-small-incision-lenticule-extraction-incidence-risk-factors-and-outcomes
#3
Yu-Chi Liu, Mohamad Rosman, Jodhbir S Mehta
PURPOSE: To report the incidence, risk factors, and outcomes of enhancement after small-incision lenticule extraction (SMILE). DESIGN: Retrospective cohort study. PARTICIPANTS: Five hundred twenty-four eyes of 307 patients who underwent SMILE at Singapore National Eye Center between February 2012 and March 2016. METHODS: The data collected included patient age at primary SMILE, gender, race, preoperative and postoperative manifest refraction spherical equivalent (MRSE), preoperative and postoperative uncorrected distance visual acuity and corrected distance visual acuity, the occurrence of suction loss during the procedure, and the need for enhancement...
March 15, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28318311/treatment-of-vertical-maxillary-excess-without-open-bite-in-a-skeletal-class-ii-hyperdivergent-patient
#4
Cheol-Ho Paik, Hong-Sik Park, Hyo-Won Ahn
A 20-year-old woman visited the office complaining of a gummy smile and lip protrusion. She was diagnosed with vertical maxillary excess without open bite and skeletal Class II hyperdivergent pattern. She refused the surgical-orthodontic treatment option, although she wanted to correct the gummy smile and retruded chin. Differential intrusion of anterior and posterior teeth in both arches was necessary to maximize the skeletal treatment effects. In the maxilla, one palatal temporary anchorage device (TAD), an archwire with an accentuated curve of Spee, and a transpalatal arch were applied...
March 20, 2017: Angle Orthodontist
https://www.readbyqxmd.com/read/28317667/small-incision-lenticule-extraction-in-a-patient-with-congenital-nystagmus
#5
Bu Ki Kim, Su Joung Mun, Dae Gyu Lee, Hyun Tae Choi, Young Taek Chung
We report a case of a 23-year-old woman with congenital nystagmus who had small-incision lenticule extraction (SMILE) procedure to correct refractive errors. The manifest refraction was -5.50 -1.75 × 180 in the right eye, -5.0 -2.50 × 180 in the left eye, and the patient presented with horizontal pendular nystagmus with an amplitude range of 5 to 10 degrees. Uneventful simultaneous bilateral small-incision lenticule extraction was performed. Six months postoperatively, the uncorrected distance visual acuity was 20/18 with -0...
January 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/28317085/perception-of-smile-esthetics-by-laypeople-of-different-ages
#6
Chompunuch Sriphadungporn, Niramol Chamnannidiadha
BACKGROUND: Age is a factor affecting smile esthetics. Three variables of smile esthetics associated with the maxillary anterior teeth and age-related changes have recently received considerable attention: (i) the incisal edge position of the maxillary central incisors, (ii) the maxillary gingival display, and (iii) the presence of a black triangle between the maxillary central incisors. The aim of this study was to evaluate the influence of age on smile esthetic perception based on these three variables in a group of Thai laypeople...
December 2017: Progress in Orthodontics
https://www.readbyqxmd.com/read/28316236/webmolcs-a-web-based-interface-for-visualizing-molecules-in-3d-chemical-spaces
#7
Mahendra Awale, Daniel Probst, Jean-Louis Reymond
The concept of chemical space provides a convenient framework to analyze large collections of molecules by placing them in property spaces where distances represent similarities. Here we report webMolCS, a new type of web-based interface visualizing up to 5000 user-defined molecules in six different 3D chemical spaces obtained by principal component analysis or similarity mapping of multi-dimensional property spaces describing composition (MQN: 42D Molecular Quantum Numbers, SMIfp: 34D SMILES fingerprint), shapes and pharmacophores (APfp: 20D atom pair fingerprint, Xfp: 55D category extended atom pair fingerprint), and substructures (Sfp: 1024D binary substructure fingerprint, ECfp4: 1024D extended connectivity fingerprint)...
March 19, 2017: Journal of Chemical Information and Modeling
https://www.readbyqxmd.com/read/28316192/-effect-of-optical-zone-diameter-on-corneal-biomechanical-properties-after-small-incision-lenticule-extraction
#8
P H Wei, Y Wang, H Li, R Dou, L Y Li, W Zhao, J M Zhang
Objective: To investigate the effect of optical zone diameter on corneal biomechanical properties after small incision lenticule extraction (SMILE). Methods: In this prospective case-control study, 62 eyes of 42 patients with myopia and myopic astigmatism that had undergone SMILE procedure were divided into 2 groups according to the optical zone (OZ) diameter: group A, 31 eyes of 19 patients, OZ= 6.5 mm; group B, 31eyes of 23 patients, OZ=6.0 mm. These patients were examined for corneal hysteresis (CH) and corneal resistance factor (CRF) with the Ocular Response Analyzer (ORA) preoperatively and at 1 week, 1 month and 3 months postoperatively; at the same time, the central corneal thickness-corrected indices of DifCH and DifCRF were calculated...
March 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/28297090/the-mandibular-muscles-in-contemporary-orthodontic-practice-a-review
#9
M G Woods
It is widely accepted that all dentists should have a thorough understanding of the muscles involved in moving or stabilizing the mandible. However, there is still much discussion regarding the influence of the mandibular muscles on normal facial growth and dental development, as well as on orthodontic treatment and post-treatment stability. Potential patients with different underlying vertical muscle patterns will have differences in the expected directions of future mandibular growth, lateral profile shape, facial and arch widths and vertical occlusal relationships...
March 2017: Australian Dental Journal
https://www.readbyqxmd.com/read/28294505/metal-free-intermolecular-aminoarylation-of-alkynes
#10
Pauline T G Rabet, Scott Boyd, Michael F Greaney
A metal-free aminoarylation of internal alkynes is described, yielding tetrasubstituted enaminoates. The transformation proceeds in good to excellent yields through a tandem conjugate addition/Smiles rearrangement involving aryl and heteroaryl sulfonamides. Substrate scope is very broad under simple, user-friendly conditions, and the reaction can be used to easily access biologically active phenethylamine derivatives.
March 13, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28293514/platysma-motor-nerve-transfer-for-restoring-marginal-mandibular-nerve-function
#11
Andres Rodriguez-Lorenzo, David Jensson, Wolfgang J Weninger, Melanie Schmid, Stefan Meng, Chieh-Han John Tzou
BACKGROUND: Injuries of the marginal mandibular nerve (MMN) of the facial nerve result in paralysis of the lower lip muscle depressors and an asymmetrical smile. Nerve reconstruction, when possible, is the method of choice; however, in cases of long nerve gaps or delayed nerve reconstruction, conventional nerve repairs may be difficult to perform or may provide suboptimal outcomes. Herein, we investigate the anatomical technical feasibility of transfer of the platysma motor nerve (PMN) to the MMN for restoration of lower lip function, and we present a clinical case where this nerve transfer was successfully performed...
December 2016: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28291201/-results-of-residual-ametropia-correction-using-circle-technology-after-femtosecond-laser-smile-surgery
#12
O A Kostin, S V Rebrikov, A I Ovchinnikov, A A Stepanov, Kh P Takhchidi
AIM: to evaluate functional results of reoperation performed according to the CIRCLE technology and using the VisuMax femtosecond laser and MEL-80 excimer laser in cases of regression of the refractive effect after SMILE surgery. MATERIAL AND METHODS: We studied a group of post-SMILE patients. In those, who showed regression of the refractive effect at 1 year, reoperation was performed according to the CIRCLE technology and using the VisuMax femtosecond laser. The corneal flap was separated from the stromal bed and turned aside...
2017: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/28289981/forcegen-3d-structure-and-conformer-generation-from-small-lead-like-molecules-to-macrocyclic-drugs
#13
Ann E Cleves, Ajay N Jain
We introduce the ForceGen method for 3D structure generation and conformer elaboration of drug-like small molecules. ForceGen is novel, avoiding use of distance geometry, molecular templates, or simulation-oriented stochastic sampling. The method is primarily driven by the molecular force field, implemented using an extension of MMFF94s and a partial charge estimator based on electronegativity-equalization. The force field is coupled to algorithms for direct sampling of realistic physical movements made by small molecules...
March 13, 2017: Journal of Computer-aided Molecular Design
https://www.readbyqxmd.com/read/28288369/phrasal-prosody-constrains-syntactic-analysis-in-toddlers
#14
Alex de Carvalho, Isabelle Dautriche, Isabelle Lin, Anne Christophe
This study examined whether phrasal prosody can impact toddlers' syntactic analysis. French noun-verb homophones were used to create locally ambiguous test sentences (e.g., using the homophone as a noun: [le bébésouris] [a bien mangé] - [the baby mouse] [ate well] or using it as a verb: [le bébé] [sourità sa maman] - [the baby] [smiles to his mother], where brackets indicate prosodic phrase boundaries). Although both sentences start with the same words (le-bebe-/suʁi/), they can be disambiguated by the prosodic boundary that either directly precedes the critical word /suʁi/ when it is a verb, or directly follows it when it is a noun...
March 10, 2017: Cognition
https://www.readbyqxmd.com/read/28282451/c-tactile-afferent-stimulating-touch-carries-a-positive-affective-value
#15
Ralph Pawling, Peter R Cannon, Francis P McGlone, Susannah C Walker
The rewarding sensation of touch in affiliative interactions is hypothesized to be underpinned by a specialized system of nerve fibers called C-Tactile afferents (CTs), which respond optimally to slowly moving, gentle touch, typical of a caress. However, empirical evidence to support the theory that CTs encode socially relevant, rewarding tactile information in humans is currently limited. While in healthy participants, touch applied at CT optimal velocities (1-10cm/sec) is reliably rated as subjectively pleasant, neuronopathy patients lacking large myelinated afferents, but with intact C-fibres, report that the conscious sensation elicited by stimulation of CTs is rather vague...
2017: PloS One
https://www.readbyqxmd.com/read/28281211/bayesian-molecular-design-with-a-chemical-language-model
#16
Hisaki Ikebata, Kenta Hongo, Tetsu Isomura, Ryo Maezono, Ryo Yoshida
The aim of computational molecular design is the identification of promising hypothetical molecules with a predefined set of desired properties. We address the issue of accelerating the material discovery with state-of-the-art machine learning techniques. The method involves two different types of prediction; the forward and backward predictions. The objective of the forward prediction is to create a set of machine learning models on various properties of a given molecule. Inverting the trained forward models through Bayes' law, we derive a posterior distribution for the backward prediction, which is conditioned by a desired property requirement...
March 9, 2017: Journal of Computer-aided Molecular Design
https://www.readbyqxmd.com/read/28276875/is-trustworthiness-lateralized-in-the-face-evidence-from-a-trust-game
#17
Daniel J Carragher, Nicole A Thomas, Michael E R Nicholls
A turn of the head can be used to convey or conceal emotion, as the left side of the face is more expressive than the right. As the left cheek moves more when smiling, the present study investigated whether perceived trustworthiness is lateralized to the left cheek, using a trust game paradigm. In Experiment 1, participants were asked to share money with male and female "virtual partners." Left-left or right-right composite faces were used to represent the partners. There were no differences in the amount shared based on composite face, suggesting trustworthiness is not lateralized in the face...
March 3, 2017: Laterality
https://www.readbyqxmd.com/read/28275603/isolated-extranodal-natural-killer-t-cell-lymphoma-of-the-orbit-in-a-young-patient-complete-regression-with-the-smile-regimen
#18
Rachna Meel, Rebika Dhiman, Meenakshi Wadhwani, Seema Kashyap, Sanjay Sharma, Ajay Gogia
PURPOSE: Natural killer T-cell lymphoma (NKTL) is a highly malignant tumor that typically arises in the nose and/or paranasal sinuses. Isolated orbital involvement by NKTL is extremely rare, and only few case reports exist in the literature. Herein, we report a case of primary orbital NKTL in a young patient who showed very good response to chemotherapy with the SMILE regimen. METHODS: A 28-year-old healthy female presented to us with epiphora and fullness of the lower eyelid...
January 2017: Ocular Oncology and Pathology
https://www.readbyqxmd.com/read/28271914/monte-carlo-method-based-qsar-modelling-of-natural-lipase-inhibitors-using-hybrid-optimal-descriptors
#19
A Kumar, S Chauhan
Obesity is one of the most provoking health burdens in the developed countries. One of the strategies to prevent obesity is the inhibition of pancreatic lipase enzyme. The aim of this study was to build QSAR models for natural lipase inhibitors by using the Monte Carlo method. The molecular structures were represented by the simplified molecular input line entry system (SMILES) notation and molecular graphs. Three sets - training, calibration and test set of three splits - were examined and validated. Statistical quality of all the described models was very good...
March 8, 2017: SAR and QSAR in Environmental Research
https://www.readbyqxmd.com/read/28268779/automated-social-skills-training-with-audiovisual-information
#20
Hiroki Tanaka, Sakriani Sakti, Graham Neubig, Hideki Negoro, Hidemi Iwasaka, Satoshi Nakamura
People with social communication difficulties tend to have superior skills using computers, and as a result computer-based social skills training systems are flourishing. Social skills training, performed by human trainers, is a well-established method to obtain appropriate skills in social interaction. Previous works have attempted to automate one or several parts of social skills training through human-computer interaction. However, while previous work on simulating social skills training considered only acoustic and linguistic features, human social skills trainers take into account visual features (e...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
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