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Pyelonephritis

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https://www.readbyqxmd.com/read/29789888/diffusion-tensor-imaging-in-acute-pyelonephritis-in-children
#1
Mickaël Lair, Mariette Renaux-Petel, Adnan Hassani, Yohann Cruypeninck, Ioana Vasies, Agnès Liard, Jean-Nicolas Dacher, Pierre-Hugues Vivier
BACKGROUND: Diffusion-weighted imaging plays a key role in the imaging of acute pyelonephritis by MRI. However the use of respiratory triggering is challenging and time-consuming in children. Diffusion tensor imaging without respiratory triggering might provide satisfying images of the moving kidneys. OBJECTIVE: To compare mean diffusivity diffusion tensor images obtained with free breathing with diffusion-weighted images obtained with respiratory triggering. MATERIALS AND METHODS: Thirty-one children with suspected acute pyelonephritis underwent axial diffusion tensor imaging acquisition with free breathing and axial and coronal diffusion-weighted imaging acquisitions with respiratory triggering...
May 22, 2018: Pediatric Radiology
https://www.readbyqxmd.com/read/29788118/risk-factors-for-treatment-failure-and-mortality-among-hospitalised-patients-with-complicated-urinary-tract-infection-a-multicentre-retrospective-cohort-study-rescuing-study-group
#2
Noa Eliakim-Raz, Tanya Babitch, Evelyn Shaw, Ibironke Addy, Irith Wiegand, Christiane Vank, Laura Torre-Vallejo, Vigo Joan-Miquel, Morris Steve, Sally Grier, Margaret Stoddart, Cuperus Nienke, Leo van den Heuvel, Cuong Vuong, Alasdair MacGowan, Jordi Carratalà, Leonard Leibovici, Miquel Pujol
Background: Complicated urinary tract infections (cUTIs) are responsible for a major share of all antibiotic consumption in hospitals. We aim to describe risk factors for treatment failure and mortality among hospitalised patients with cUTIs. Methods: A multinational, multicentre retrospective cohort study, conducted in 20 countries in Europe and the Middle East. Data were collected from patients' files on hospitalised patients with a diagnosis of cUTI during 2013-2014...
May 17, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29787375/transperitoneal-laparoscopic-heminephroureterectomy-in-pediatric-population-a-single-centre-experience-using-a-sealing-device
#3
Ibrahim Aydogdu, Mesrur Selcuk Silay
INTRODUCTION: We sought to report the outcomes of transperitoneal laparoscopic heminephroureterectomy (LHNU) in pediatric population and to describe the technical details of this minimally invasive surgery. METHODS: Seventeen pediatric patients (18 renal units), who had consecutive transperitoneal LHNU in our department between January 2012 and July 2017 were included in the study. In all patients, diagnostic cystoscopy and retrograde pyelography were carried out immediately before the operation...
May 14, 2018: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/29779678/spontaneous-perirenal-hemorrhage-wunderlich-syndrome-an-analysis-of-28-cases
#4
Jong Wook Kim, Jung Youn Kim, Sun Tae Ahn, Tae Yong Park, Mi Mi Oh, Du Geon Moon, Hong Seok Park
INTRODUCTION: This study aimed to analyze the characteristics, etiology, and treatment of a series of patients with spontaneous perirenal hemorrhage (Wunderlich syndrome [WS]). METHODS: We retrospectively reviewed the records of 26 patients hospitalized for WS in a tertiary urological center between 2011 and 2018. All patients were evaluated for perirenal hemorrhage observed on computed tomography (CT) in the emergency department. Clinical variables (age, underlying diseases, symptoms, shock, and hospitalization period), laboratory test results, and radiological and pathological results were reviewed...
April 21, 2018: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29778699/re-diffusion-weighted-magnetic-resonance-imaging-is-more-sensitive-than-dimercaptosuccinic-acid-scintigraphy-in-detecting-parenchymal-lesions-in-children-with-acute-pyelonephritis-a-prospective-study
#5
https://www.readbyqxmd.com/read/29770220/characterization-of-the-macrophage-infiltrate-in-a-case-of-xanthogranulomatous-pyelonephritis
#6
Jelani C Zarif, Heather J Chalfin, Phillip M Pierorazio, Michael A Gorin
No abstract text is available yet for this article.
May 2018: Journal of Clinical Urology
https://www.readbyqxmd.com/read/29768465/stopping-the-effective-non-fluoroquinolone-antibiotics-at-day-7-vs-continuing-until-day-14-in-adults-with-acute-pyelonephritis-requiring-hospitalization-a-randomized-non-inferiority-trial
#7
Pavankumar Rudrabhatla, Surendran Deepanjali, Jharna Mandal, Rathinam Palamalai Swaminathan, Tamilarasu Kadhiravan
OBJECTIVE: To evaluate whether stopping the effective antibiotic treatment following clinical improvement at Day 7 (Truncated treatment) would be non-inferior to continued treatment until Day 14 (Continued treatment) in patients with acute pyelonephritis (APN) requiring hospitalization treated with non-fluoroquinolone (non-FQ) antibiotics. METHODS: Hospitalized adult men and non-pregnant women with culture-confirmed APN were eligible for participation after they had clinically improved following empirical or culture-guided treatment with intravenous non-FQ antibiotic(s)...
2018: PloS One
https://www.readbyqxmd.com/read/29768293/seasonality-of-common-pediatric-infectious-diseases
#8
Susan C Lipsett, Michael C Monuteaux, Andrew M Fine
BACKGROUND/OBJECTIVE: Traditional sources cite seasonal patterns for common infectious diseases, often based on microbiologic data, but little is known about cyclical trends in clinically diagnosed infectious conditions in the emergency department (ED). We leveraged the publicly available Nationwide Emergency Department Sample database to measure the seasonality of the most common pediatric infectious diseases diagnosed in US EDs. METHODS: We searched the Nationwide Emergency Department Sample database to identify infectious diagnoses comprising at least 1% of all diagnosis codes ascribed to patients 21 years and younger in US EDs from 2009 to 2013...
May 15, 2018: Pediatric Emergency Care
https://www.readbyqxmd.com/read/29767316/-ceus-diagnosis-of-solid-renal-tumors
#9
REVIEW
K Stock, H Kübler, T Maurer, J Slotta-Huspenina, K Holzapfel
CLINICAL ISSUE: Renal lesions are detected earlier, often as a result of ultrasound examinations. However, the imaging-based differential diagnosis of different tumour entities remains challenging STANDARD RADIOLOGICAL METHODS: All renal tumours >1 cm should be evaluated for malignancy by computed tomography (CT) or magnetic resonance imaging (MRI). If an angiomyolipoma diagnosis cannot be established with imaging, further diagnostics are appropriate or if malignant progression is suspected, then multidisciplinary discussion for TNM-staging based uro-oncologic therapy is usual...
May 16, 2018: Der Radiologe
https://www.readbyqxmd.com/read/29763434/ibuprofen-versus-pivmecillinam-for-uncomplicated-urinary-tract-infection-in-women-a-double-blind-randomized-non-inferiority-trial
#10
Ingvild Vik, Marianne Bollestad, Nils Grude, Anders Bærheim, Eivind Damsgaard, Thomas Neumark, Lars Bjerrum, Gloria Cordoba, Inge Christoffer Olsen, Morten Lindbæk
BACKGROUND: Although uncomplicated urinary tract infections (UTIs) are often self-limiting, most patients will be prescribed antibiotic treatment. We assessed whether treatment with ibuprofen was non-inferior to pivmecillinam in achieving symptomatic resolution by day 4, with a non-inferiority margin of 10%. METHODS AND FINDINGS: This was a randomized, controlled, double-blind non-inferiority trial. We recruited patients from 16 sites in a general practice setting in Norway, Sweden, and Denmark...
May 2018: PLoS Medicine
https://www.readbyqxmd.com/read/29758033/phylogenetic-relationships-biofilm-formation-motility-antibiotic-resistance-and-extended-virulence-genotypes-among-escherichia-coli-strains-from-women-with-community-onset-primitive-acute-pyelonephritis
#11
Arianna Pompilio, Valentina Crocetta, Vincenzo Savini, Dezemona Petrelli, Marta Di Nicola, Silvia Bucco, Luigi Amoroso, Mario Bonomini, Giovanni Di Bonaventura
The present work set out to search for a virulence repertoire distinctive for Escherichia coli causing primitive acute pyelonephritis (APN). To this end, the virulence potential of 18 E. coli APN strains was genotypically and phenotypically assessed, comparatively with 19 strains causing recurrent cystitis (RC), and 16 clinically not significant (control, CO) strains. Most of the strains belong to phylogenetic group B1 (69.8%; p<0.01), and APN strains showed unique features, which are the presence of phylogroup A, and the absence of phylogroup B2 and non-typeable strains...
2018: PloS One
https://www.readbyqxmd.com/read/29753570/xanthogranulomatous-pyelonephritis-a-complicated-febrile-urinary-tract-infection-detected-by-point-of-care-ultrasound-in-the-emergency-department
#12
Ryan Gibbons, Nicole Leonard, Mark Magee, Allison Zanaboni, Jessica Patterson, Thomas Costantino
BACKGROUND: Febrile urinary tract infections (UTIs) include a spectrum of pathologies from uncomplicated pyelonephritis to urosepsis, including xanthogranulomatous pyelonephritis (XGP). Most febrile UTIs are treated with antibiotics alone, but studies indicate nearly 12% of cases of presumed simple pyelonephritis require emergent urologic intervention. How to identify these individuals, while limiting unnecessary advanced imaging and delays in diagnosis, challenges all emergency providers...
May 9, 2018: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29747905/prospective-evaluation-of-the-management-of-urinary-tract-infections-in-134-french-nursing-homes
#13
L Lemoine, C Dupont, A Capron, E Cerf, M Yilmaz, D Verloop, K Blanckaert, E Senneville, S Alfandari
OBJECTIVE: Prospective assessment of the management of urinary tract infections (UTI) in the nursing homes of the Hauts-de-France region. PATIENTS AND METHODS: A 50-question form had to be filled in for up to five consecutive residents treated for UTI in each nursing home. If necessary, diagnoses were reclassified according to the 2014 French Infectious Diseases Society guidelines. Analyses were presented per supposed (reported) and reclassified diagnoses. RESULTS: Of 397 contacted facilities, 134 participated and informed 444 UTI episodes...
May 7, 2018: Médecine et Maladies Infectieuses
https://www.readbyqxmd.com/read/29747234/laparoscopic-nephrectomy-in-a-patient-with-severe-scoliosis-a-case-report
#14
Daichi Tamura, Ayato Ito, Daichi Kikuchi, Takashi Tsuyukubo, Renpei Kato, Yoichiro Kato, Susumu Konari, So Omori, Wataru Obara
Although the role of laparoscopic nephrectomy (LN) has been established, few studies have reported cases of LN in individuals with scoliosis. Here we report a case of right LN in a patient with severe right convex scoliosis. A 26-year-old man presented with a fever. His medical history comprised severe right convex lumbar scoliosis. CT revealed right hydronephrosis and right kidney stones. Pyelonephritis requiring nephrectomy was diagnosed. Right LN was feasible with elaborate perioperative care. The postoperative course was uneventful with no relapse of urinary tract infection...
May 10, 2018: Asian Journal of Endoscopic Surgery
https://www.readbyqxmd.com/read/29736094/influence-of-plasminogen-activator-inhibitor-1-gene-polymorphism-on-renal-scarring-after-first-febrile-urinary-tract-infection-in-infants
#15
Danka Pokrajac, Lejla Kapur-Pojskic, Sandra Vegar-Zubovic, Renata Milardovic
Background: The pathogenesis of renal scarring (RS) after first febrile urinary tract infection (UTI) in children is multifactorial. In addition to well-known risk factors, a role for genetic predisposition has been suggested. Aims: To determine whether deoxyribonucleic acid (DNA) polymorphisms at the plasminogen activator inhibitor -1 (PAI-1) gene were associated with evolution to RS following a febrile UTI in infants. Materials and Methods: Our research included 100 infants, 84 girls and 16 boys, ages up to 1 year with a first febrile UTI, increased inflammatory parameters and positive urine culture treated at the Pediatric Clinic II of the University Clinical Center Sarajevo (UCCS)...
April 2018: Medical Archives
https://www.readbyqxmd.com/read/29732228/de-novo-atypical-haemolytic-uremic-syndrome-after-kidney-transplantation
#16
Arnaud Devresse, Martine de Meyer, Selda Aydin, Karin Dahan, Nada Kanaan
De novo thrombotic microangiopathy (TMA) can occur after kidney transplantation. An abnormality of the alternative pathway of complement must be suspected and searched for, even in presence of a secondary cause. We report the case of a 23-year-old female patient who was transplanted with a kidney from her mother for end-stage renal disease secondary to Hinman syndrome. Early after transplantation, she presented with 2 episodes of severe pyelonephritis, associated with acute kidney dysfunction and biological and histological features of TMA...
2018: Case Reports in Nephrology
https://www.readbyqxmd.com/read/29729161/antimicrobial-susceptibility-patterns-of-escherichia-coli-in-children-and-adults-with-urinary-tract-infections
#17
Yaroslav O Mykhalko
OBJECTIVE: Introduction: Urinary tract infections (UTIs) are common pathology in children and adults that is caused mainly by Gram-negative bacteria among which Escherichia coli plays an outstanding role. UTIs treatment demands empiric antibiotic therapy and knowing of antimicrobial local susceptibility and resistance patterns is crucial for making a decision about an agent for the first line therapy. The aim of this study was to evaluate the local susceptibility patterns of uropathogenic E...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29727865/prospective-study-on-several-urinary-biomarkers-as-indicators-of-renal-damage-in-children-with-cakut
#18
Fabio Bartoli, Valentina Pastore, Isabella Calè, Gabriella Aceto, Vittoria Campanella, Carla Lasalandra, Simona Magaldi, Francesco Niglio, Angela Basile, Raffaella Cocomazzi
PURPOSE:  The aim of the study was to investigate urinary levels of monocyte chemotactic protein-1 (MCP-1), epidermal growth factor (EGF), β-2-microglobulin (β2M), and FAS-ligand (FAS-L) in children with congenital anomalies of kidney and urinary tract (CAKUT) disease at risk of developing glomerular hyperfiltration syndrome. For this reason, we selected patients with multicystic kidney, renal agenesia and renal hypodysplasia, or underwent single nephrectomy. MATERIALS AND METHODS:  This prospective, multicentric study was conducted in collaboration between the Pediatric Surgery Unit in Foggia and the Pediatric Nephrology Unit in Bari, Italy...
May 4, 2018: European Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29725629/acute-kidney-injury-in-pregnancy-the-changing-landscape-for-the-21st-century
#19
REVIEW
Swati Rao, Belinda Jim
Pregnancy-related acute kidney injury (Pr-AKI) remains a large public health problem, with decreasing incidences in developing countries but seemingly increasing incidences in the United States and Canada. These epidemiologic changes are reflective of the advances in medical and obstetric care, as well as changes in underlying maternal risk factors. The risk factors associated with advanced maternal age, such as hypertension, diabetes, chronic kidney disease, and those associated with reproductive technologies such as multiple gestations, are increasing...
March 2018: KI Reports
https://www.readbyqxmd.com/read/29709389/unusual-presentation-of-emphysematous-pyelonephritis-with-extension-to-the-scrotum-and-leg
#20
E O Piñón Solis, J García Ramirez, J F Gil Garcia
No abstract text is available yet for this article.
April 27, 2018: Revista Clínica Española
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