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Pyelonephritis

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https://www.readbyqxmd.com/read/29142969/elucidation-of-renal-scars-in-children-with%C3%A2-vesicoureteral-reflux-using-contrast-enhanced-ultrasound-a-pilot%C3%A2-study
#1
David S Hains, Harris L Cohen, M Beth McCarville, Ellen E Ellison, Amy Huffman, Stacey Glass, Aslam H Qureshi, Keith R Pierce, Ashlyn L Cahill, Ashley Dixon, Noel Delos Santos
Introduction: Vesicoureteral reflux is a common disorder in children but can result in kidney scarring following acute pyelonephritis. The gold standard diagnostic to detect renal scars in children is (99m)Tc-dimercaptosuccinic acid (DMSA) scintigraphy. DMSA has a number of limitations including radiation exposure, need for sedation, and radiotracer supply shortages. Contrast-enhanced ultrasound (CEUS) is a technique whereby biocompatible microspheres of inert gas are administered i.v...
May 2017: KI Reports
https://www.readbyqxmd.com/read/29138582/once-daily-intramuscular-amikacin-for-outpatient-treatment-of-lower-urinary-tract-infections-caused-by-extended-spectrum-%C3%AE-lactamase-producing-escherichia-coli-in-children
#2
Meltem Polat, Soner Sertan Kara
Background: The rise in community-acquired urinary tract infections (UTIs) with extended-spectrum β-lactamase (ESBL)-producing Escherichia coli strains raises the question of how to treat these infections effectively in pediatric outpatients. Amikacin has shown promising in vitro activity against ESBL-producing urinary isolates of E. coli; however, clinical data are limited. Objective: To investigate the clinical and microbiological outcomes of community-acquired lower UTIs caused by ESBL-producing E...
2017: Infection and Drug Resistance
https://www.readbyqxmd.com/read/29137105/urgent-laparoscopic-ureterolithotomy-for-proximal-ureter-stones-accompanied-with-obstructive-pyelonephritis-is-it-safe-and-effective-without-preoperative-drainage
#3
Huan Yang, Xiao Yu, Ejun Peng, Cong Li, Lei Cui, Xing Zeng, Shen Wang, Chao Wei, Zhihua Wang, Xiaolin Guo, Zhiqiang Chen, Zhangqun Ye, Shaogang Wang, Chenming Zhao
To evaluate the safety and efficacy of retroperitoneal laparoscopic ureterolithotomy (RLU) in the treatment of proximal ureteral stones accompanied with obstructive pyelonephritis without preoperative drainage.We retrospectively reviewed 21 cases of proximal ureteral stones with infected kidney undergoing RLU between July 2013 and September 2016. Stone-induced obstructive infected hydronephrosis was diagnosed using blood and urine tests and imaging modalities. Empirical effective broad spectrum antibiotic therapy was initiated immediately, and then urgent RLU was performed without preoperative drainage...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29134126/the-urinary-and-serum-levels-of-il-32-in-children-with-febrile-urinary-tract-infections
#4
Alireza Rafiei, Hamid Mohammadjafari, Ayat Ahifar, Abbas Alipour, Araz Mohammad Mirabi
Aim: We assessed the urinary and serum levels of IL-32 in pediatric patients with acute pyelonephritis (APN) with and without renal scarring. Results: We enrolled children aged 2 months to 16 years with APN. Dimercaptosuccinic acid scans and ultrasonography studies were ordered for all patients, and a voiding. A total of 86 children (aged 57 ± 39 months, 74 [86%] female) were enrolled in this study. Group 1 was composed of 19 (16 female) patients, group 2 of 38 (35 female) patients and group 3 of 29 (23 female) patients...
November 2017: Future Science OA
https://www.readbyqxmd.com/read/29124412/evaluation-of-a-short-formation-on-the-performance-of-point-of-care-renal-ultrasound-performed-by-physicians-without-previous-ultrasound-skills-prospective-observational-study
#5
François Javaudin, François Mounier, Philippe Pes, Idriss Arnaudet, Frédéric Vignaud, Eric Frampas, Philippe Le Conte
BACKGROUND: Point-of-Care Ultrasound (PoCUS) is recommended by emergency medicine societies for the detection of hydronephrosis. Training of certified Emergency Physicians (EP) without prior ultrasound experience remains debated. We investigate performance of a brief training session for the detection of hydronephrosis with PoCUS performed by EP without previous ultrasound experience. PATIENTS AND METHODS: This was a prospective observational study of a convenience sample of patients older than 18 years with presumed renal colic, acute pyelonephritis or documented acute renal failure...
November 9, 2017: Critical Ultrasound Journal
https://www.readbyqxmd.com/read/29123906/two-cases-with-intra-aortic-balloon-pumping-use-for-severe-septic-cardiomyopathy
#6
Taro Hiromi, Chiaki Toida, Takashi Muguruma, Katsutaka Hashiba, Tomoki Doi, Kyota Nakamura, Naoto Morimura
Cases: Septic cardiomyopathy is defined as a reversible left ventricular systolic dysfunction. Patients with severe septic cardiomyopathy have a high mortality rate, even if they receive conventional therapy. For those patients, previous reports showed intra-aortic balloon pump (IABP) efficacy. We report two rare cases with IABP introduction leading them to drastic improvement, and survival from severe septic cardiomyopathy. Case 1 is a 78-year-old woman diagnosed with renal calculus pyelonephritis, septic shock, and septic cardiomyopathy...
October 2017: Acute Medicine & Surgery
https://www.readbyqxmd.com/read/29113968/symptomatic-treatment-of-uncomplicated-lower-urinary-tract-infections-in-the-ambulatory-setting-randomised-double-blind-trial
#7
RANDOMIZED CONTROLLED TRIAL
Andreas Kronenberg, Lukas Bütikofer, Ayodele Odutayo, Kathrin Mühlemann, Bruno R da Costa, Markus Battaglia, Damian N Meli, Peter Frey, Andreas Limacher, Stephan Reichenbach, Peter Jüni
Objective To investigate whether symptomatic treatment with non-steroidal anti-inflammatory drugs (NSAIDs) is non-inferior to antibiotics in the treatment of uncomplicated lower urinary tract infection (UTI) in women, thus offering an opportunity to reduce antibiotic use in ambulatory care.Design Randomised, double blind, non-inferiority trial.Setting 17 general practices in Switzerland.Participants 253 women with uncomplicated lower UTI were randomly assigned 1:1 to symptomatic treatment with the NSAID diclofenac (n=133) or antibiotic treatment with norfloxacin (n=120)...
November 7, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29100793/discrimination-of-culture-negative-pyelonephritis-in-children-with-suspected-febrile-urinary-tract-infection-and-negative-urine-culture-results
#8
Jun Ho Lee
BACKGROUND: We investigated whether the C-reactive protein (CRP) level, urine electrolytes, and urine sodium-potassium ratio (uNa/K) could be useful markers for discriminating children with culture negative pyelonephritis (CNP) from children with suspected febrile urinary tract infection (fUTI) and negative urine culture results. METHODS: We examined 264 children experiencing their first fUTI consecutively admitted to our hospital between January 2011 and October 2014...
October 25, 2017: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://www.readbyqxmd.com/read/29098124/foley-follies-emphysematous-pyelitis-from-instrumentation-in-obstructive-uropathy
#9
Shimshon Wiesel, Anna Gutman, Jonah E Abraham, Militza Kiroycheva
Emphysematous pyelitis (EP) is a subclass of a life-threatening necrotizing infection of the urinary system called emphysematous pyelonephritis (EPN). We report a case of an 81-year-old man with emphysematous pyelitis, which occurred after urinary tract instrumentation and resolved with conservative medical management. This case highlights the potential complications of urinary tract manipulation and the importance of a prompt diagnosis.
August 26, 2017: Curēus
https://www.readbyqxmd.com/read/29090653/tuberculous-pyelonephritis-in-children-three-case-reports
#10
Nimisha Arora, Abhijeet Saha, Manpreet Kaur
Tuberculous pyelonephritis is rare in children; three case reports are presented. Case 1 was an 11-year-old girl with a previous history of pulmonary tuberculosis who presented with flank pain and fever for 10 days. An ultrasound suggested focal pyelonephritis, and a contrast-enhanced computed tomography (CECT) scan demonstrated acute focal pyelonephritis and a perinephric collection. Mycobacterium tuberculosis was cultured in the urine. She responded well to anti-tuberculous treatment (ATT). Case 2 was a 13-year-old boy who presented with fever, haematuria, burning micturition, proteinuria (3+) and cervical lymphadenopathy...
November 1, 2017: Paediatrics and International Child Health
https://www.readbyqxmd.com/read/29090027/evaluation-of-multidetector-computed-tomography-in-haematuria
#11
Ranjan Kumar, Raj Kumar Airon, Amit Mittal, Rikki Singal, Kamal Sharma, Samita Singal
AIMS AND OBJECTIVES: (1) To study the role of multidetector computed tomography in patients with haematuria. (2) To correlate multidetector computed tomography findings with clinical outcome/laboratory findings/FNAC and/or operative findings (wherever performed). MATERIAL AND METHODS: The present study was carried out in the Department of Radiodiagnosis, M.M. Institute of Medical Sciences and Research, Mullana, Ambala, from April 2014 to 2016. Fifty patients with complaint of haematuria, referred from various wards and outpatient departments of this institution, were included...
June 2017: Mædica
https://www.readbyqxmd.com/read/29089041/the-increasing-rates-of-acute-interstitial-nephritis-in-australia-a-single-centre-case-series
#12
Gregory J Wilson, Adrian L Kark, Leo P Francis, Wendy Hoy, Helen G Healy, Andrew J Mallett
BACKGROUND: The Australian Institute of Health and Welfare's first report into acute kidney injury demonstrated a significant increase in the incidence of acute-tubulo interstitial nephritis, the ICD-10 code representing both acute interstitial nephritis and pyelonephritis, in women aged less than 55 years. In contrast, recent case series have reported rising rates of drug induced acute interstitial nephritis predominantly among elderly patients. Due to several limitations with the Australian Institute of Health and Welfare report, this new trend requires further investigation to determine if rates of acute interstitial nephritis are truly increasing among younger Australian women...
October 31, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/29078794/the-impact-of-daily-temperature-on-renal-disease-incidence-an-ecological-study
#13
Matthew Borg, Peng Bi, Monika Nitschke, Susan Williams, Stephen McDonald
BACKGROUND: Extremely high temperatures over many consecutive days have been linked to an increase in renal disease in several cities. This is becoming increasingly relevant with heatwaves becoming longer, more intense, and more frequent with climate change. This study aimed to extend the known relationship between daily temperature and kidney disease to include the incidence of eight temperature-prone specific renal disease categories - total renal disease, urolithiasis, renal failure, acute kidney injury (AKI), chronic kidney disease (CKD), urinary tract infections (UTIs), lower urinary tract infections (LUTIs) and pyelonephritis...
October 27, 2017: Environmental Health: a Global Access Science Source
https://www.readbyqxmd.com/read/29076901/unexpected-pyelonephritis-incidentally-revealed-on-99mtc-mdp-bone-scintigraphy
#14
Xiaofei Zhao, Ruifang Zhao, Ha Wu
A 5-year-old girl had intermittent fever for 4 months. A Tc MDP bone scintigraphy was performed to evaluate possible occult osteomyelitis, which revealed no bone lesion. However, abnormal MDP activity in the upper poles of both kidneys was noted, which was confirmed as pyelonephritis subsequently.
October 26, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/29075296/xanthogranulomatous-pyelonephritis-with-incomplete-double-ureter
#15
Yutaro Hayashi, Takashi Kawahara, Yusuke Hattori, Kota Shimokihara, Sohgo Tsutsumi, Daiji Takamoto, Taku Mochizuki, Jun-Ichi Teranishi, Yasushi Yumura, Yasuhide Miyoshi, Masako Otani, Hiroji Uemura
INTRODUCTION: Xanthogranulomatous pyelonephritis (XGP) is a type of chronic renal inflammation that usually occurs in immunocompromised middle-aged women with chronic urinary tract infection or ureteral obstruction induced by the formation of ureteral stones. XGP with an incomplete double ureter is extremely rare. CASE PRESENTATION: A 76-year-old woman was referred to our department to undergo further examination for a left renal tumor that was detected by ultrasonography...
2017: Case Reports in Medicine
https://www.readbyqxmd.com/read/29069028/factors-associated-with-severe-sepsis-or-septic-shock-in-complicated-pyelonephritis
#16
Juan D Ruiz-Mesa, Ignacio Marquez-Gomez, Gabriel Sena, Veronica A Buonaiuto, Juan Mora Ordoñez, Manuel Salido, Antonio Plata Ciézar, Lucía Valiente-De Santis, Concepción Mediavilla, Juan D Colmenero
Severe sepsis or septic shock are the main factors influencing the prognosis of acute pyelonephritis (APN). Our aim was to analyze factors associated with the development of severe sepsis or septic shock in a large sample of patients with acute complicated pyelonephritis (ACPN).This prospective observational study comprised 1507 consecutive patients aged 14 years or older who were admitted to a tertiary care hospital because of ACPN between 1997 and 2015. Covariates associated in univariate analysis with severe sepsis or septic shock were then analyzed by multivariate logistic regression...
October 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29067019/porcine-models-of-biofilm-infections-with-focus-on-pathomorphology
#17
REVIEW
Louise K Jensen, Anne S B Johansen, Henrik E Jensen
Bacterial biofilm formation is one of the main reasons for a negative treatment outcome and a high recurrence rate for many chronic infections in humans. The optimal way to study both the biofilm forming bacteria and the host response simultaneously is by using discriminative, reliable, and reproducible animal models of the infections. In this review, the advantages of in vivo studies are compared to in vitro studies of biofilm formation in infectious diseases. The pig is the animal of choice when developing and applying large animal models of infectious diseases due to its similarity of anatomy, physiology, and immune system to humans...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29065405/risk-factors-for-uroseptic-shock-in-patients-with-urolithiasis-related-acute-pyelonephritis
#18
Hiroaki Kakinoki, Shohei Tobu, Yuka Kakinoki, Kazuma Udo, Jiro Uozumi, Mitsuru Noguchi
OBJECTIVES: To analyze the risk factors of uroseptic shock induced by calculous acute pyelonephritis (APN). METHODS: This study included 69 patients (41 were women and 28 were men) who were admitted to our hospital for APN treatment associated with urolithiasis during the period from January 2005 to December 2012. We reviewed the electronic medical records of these patients to analyze risk factors contributing to the development of uroseptic shock from APN in patients with urolithiasis...
October 24, 2017: Urologia Internationalis
https://www.readbyqxmd.com/read/29055617/qualitative-and-quantitative-radiological-analysis-of-non-contrast-ct-is-a-strong-indicator-in-patients-with-acute-pyelonephritis
#19
Fadi El-Merhi, May Mohamad, Ali Haydar, Lena Naffa, Rami Nasr, Nadine Hamieh, Ziad Tayara, Charbel Saade
OBJECTIVE: To evaluate the performance of non-contrast computed tomography (CT) by reporting the difference in attenuation between normal and inflamed renal parenchyma in patients clinically diagnosed with acute pyelonephritis (APN). MATERIAL AND METHODS: This is a retrospective study concerned with non-contrast CT evaluation of 74 patients, admitted with a clinical diagnosis of APN and failed to respond to 48h antibiotics treatment. Mean attenuation values in Hounsfield units (HU) were measured in the upper, middle and lower segments of the inflamed and the normal kidney of the same patient...
September 18, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29039350/the-toxicity-of-vanadium-on-gastrointestinal-urinary-and-reproductive-system-and-its-influence-on-fertility-and-fetuses-malformations
#20
Aleksandra Wilk, Dagmara Szypulska-Koziarska, Barbara Wiszniewska
Vanadium is a transition metal that has a unique and beneficial effect on both humans and animals. For many years, studies have suggested that vanadium is an essential trace element. Its biological properties are of interest due to its therapeutic potential, including in the treatment of diabetes mellitus. Vanadium deficiencies can lead to a range of pathologies. However, excessive concentration of this metal can cause irreversible damage to various tissues and organs. Vanadium toxicity mainly manifests in gastrointestinal symptoms, including diarrhea, vomiting, and weight reduction...
September 25, 2017: Postȩpy Higieny i Medycyny Doświadczalnej
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