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Pyelonephritis

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https://www.readbyqxmd.com/read/27909584/pyelonephritis-due-to-brucella-species-true-clinical-entity-or-ghost-disease
#1
N G Vallianou, E Geladari, K Trigkidis, E Kokkinakis
No abstract text is available yet for this article.
January 2017: New Microbes and New Infections
https://www.readbyqxmd.com/read/27906107/previously-undiagnosed-hereditary-spherocytosis-in-a-patient-with-jaundice-and-pyelonephritis-a-case-report
#2
Yuki Tateno, Ryoji Suzuki, Yukihiro Kitamura
BACKGROUND: Hereditary spherocytosis is autosomal dominant inherited extravascular hemolytic disorder and is the commonest cause of inherited hemolysis in northern Europe and the United States. The classical clinical features of hereditary spherocytosis are anemia, jaundice, and splenomegaly. However, all of these classical features are not always revealed in the case of mild hemolysis or when hemolysis is well compensated. Patients with hereditary spherocytosis may remain undiagnosed for years if their hemolysis is mild...
December 1, 2016: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/27900089/pregnancy-and-cesarean-delivery-after-multimodal-therapy-for-vulvar-carcinoma-a-case-report
#3
Kuniaki Toriyabe, Haruki Taniguchi, Tokihiro Senda, Masako Nakano, Yoshinari Kobayashi, Miho Izawa, Hirohiko Tanaka, Tetsuo Asakura, Tsutomu Tabata, Tomoaki Ikeda
Reports of pregnancy following treatment for vulvar carcinoma are extremely uncommon, as the main problem of subsequent pregnancy is vulvar scarring following radical surgery. We herein report the case of a patient who was diagnosed with stage I squamous cell carcinoma of the vulva at the age of 17 years and was treated with multimodal therapy, including neoadjuvant chemotherapy, wide local excision with bilateral inguinal lymph node dissection and adjuvant radiotherapy. The patient became pregnant spontaneously 9 years after her initial diagnosis and the antenatal course was good, except for mild acute pyelonephritis at 25 weeks of gestation...
November 2016: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/27891373/retrospective-comparison-of-clinical-characteristics-and-in-hospital-outcomes-among-diabetic-and-non-diabetic-adults-with-acute-pyelonephritis
#4
Shailesh C Trivedi, Sanjeev R Phatak, Renu S Trivedi
INTRODUCTION: Acute Pyelonephritis (APN) is a common infection in community. Diabetes Mellitus (DM) may have different effect on clinical characteristics and outcomes of APN compared to non-diabetic individuals. AIM: To compare clinical characteristics and assess outcomes of APN patients with and without DM. MATERIALS AND METHODS: A retrospective analysis of 122 patients with DM (n=61) and without DM (n=61) was conducted at a single, private, urban set-up from Gujarat, India...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27889429/plasmatic-presepsin-scd14-st-concentrations-in-acute-pyelonephritis-in-adult-patients
#5
Yann-Erick Claessens, Eloise Trabattoni, Sophie Grabar, Laurent Quinquis, Guillaume Der Sahakian, Marine Anselmo, Jeannot Schmidt, Jean-Emmanuel de la Coussaye, Patrick Plaisance, Enrique Casalino, Gilles Potel, François Lecomte, Didier Borderie, Camille Chenevier-Gobeaux
INTRODUCTION: Presepsin (sCD14-ST) is an emerging biomarker for infection. We hypothesized that presepsin could specifically increase during acute pyelonephritis and correlate with severity. METHODS: We compared presepsin values in patients with acute pyelonephritis and controls, and we assessed its capacity to predict bacteraemia and admission in patients. RESULTS: In 312 patients with acute pyelonephritis (median age 33years), presepsin concentrations were higher than in controls (476 vs 200ng/L, p<0...
November 24, 2016: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/27887579/outcomes-of-high-dose-levofloxacin-therapy-remain-bound-to-the-levofloxacin-minimum-inhibitory-concentration-in-complicated-urinary-tract-infections
#6
Eliana S Armstrong, Janelle A Mikulca, Daniel J Cloutier, Caleb A Bliss, Judith N Steenbergen
BACKGROUND: Fluoroquinolones are a guideline-recommended therapy for complicated urinary tract infections, including pyelonephritis. Elevated drug concentrations of fluoroquinolones in the urine and therapy with high-dose levofloxacin are believed to overcome resistance and effectively treat infections caused by resistant bacteria. The ASPECT-cUTI phase 3 clinical trial (ClinicalTrials.gov, NCT01345929 and NCT01345955 , both registered April 28, 2011) provided an opportunity to test this hypothesis by examining the clinical and microbiological outcomes of high-dose levofloxacin treatment by levofloxacin minimum inhibitory concentration...
November 25, 2016: BMC Infectious Diseases
https://www.readbyqxmd.com/read/27882751/-septic-shock-in-pregnancy-on-the-basis-of-an-acute-pyelonephritis
#7
Z Kokrdová, A Pařízek, M Koucký, A Pašková, B Boudová
OBJECTIVE: According to the World Health Organisation, sepsis is one of the four main causes of pregnancy-related mortality worldwide, together with hemorrhage, hypertensive disease and abortion. The main goal of this paper is an analysis of one case of septic shock in pregnancy. DESIGN: A case report. SETTING: Department of Obstetrics and Gynaecology of the First Faculty of Medicine and General Teaching Hospital, Prague. METHODS AND RESULTS: Authors would like to draw attention to the pitfalls of diagnosis and treatment of septic shock which developed in 25th week of pregnancy on the basis of pyelonephritis due to E...
2016: Ceská Gynekologie
https://www.readbyqxmd.com/read/27879491/18f-fdg-pet-ct-in-renal-infections-evidence-of-acute-pyelonephritis-in-a-horseshoe-kidney
#8
Maxime Morelle, Alice Jaillard, Dimitri Bellevre, Guillaume Collet, Grégory Petyt
A 58-year-old paraplegic patient was prescribed F-FDG for persistent inflammatory syndrome after aortic surgery for dissection. The examination was performed on a Siemens mCT Flow PET/CT and shows a moderate prostate uptake, related to prostatitis on self-catheterization and a focal renal cortical hypermetabolism of the left medial midpole of a horseshoe kidney, which corresponds to renal parenchyma on the CT, and suggests pyelonephritis, confirmed by Tc-DMSA SPECT/CT.
November 22, 2016: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/27876693/a-case-of-septic-shock-due-to-serratia-marcescens-pyelonephritis-and-bacteremia-in-a-patient-receiving-empagliflozin
#9
Wesley D Kufel, Ali Scrimenti, Jeffrey M Steele
Sodium-glucose cotransporter 2 (SGLT2) inhibitors have been associated with serious urinary tract infections (UTIs) including pyelonephritis and urosepsis. The Food and Drug Administration (FDA) issued a label change to include this warning in December 2015 due to a small number of cases (n = 19) reported to the FDA Adverse Event Reporting System. Details of these cases are limited and none involved empagliflozin. To date, there has been no published literature comprehensively describing serious UTIs attributed to empagliflozin...
November 21, 2016: Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/27876276/piperacillin-tazobactam-as-an-alternative-antibiotic-therapy-to-carbapenems-in-the-treatment-of-urinary-tract-infections-due-to-extended-spectrum-%C3%AE-lactamase-producing-enterobacteriaceae-an-in-silico-pharmacokinetic-study
#10
Hélène Guet-Revillet, Elise Tomini, Aurélie Emirian, Olivier Join-Lambert, Hervé Lécuyer, Jean-Ralph Zahar, Vincent Jullien
Piperacillin/tazobactam (TZP) as an alternative treatment to carbapenems for infections involving extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae (ESBL-PE) remains debated. In this study, the probabilities of pharmacodynamic (PD) target attainment with different TZP regimens in ESBL-producing Escherichia coli (ESBL-Ec) and Klebsiella pneumoniae (ESBL-Kp) were evaluated in the context of pyelonephritis. Minimum inhibitory concentrations (MICs) of 144 ESBL-Ec and 111 ESBL-Kp from pyelonephritis were measured, and two previously published population pharmacokinetic models were used to determine by Monte Carlo simulation the probabilities of reaching two PD targets (50%fT>MIC and 100%fT>MIC) with TZP doses of 4 g three times daily and 4...
November 15, 2016: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/27867853/treatment-of-vesico-ureteral-reflux-in-infants-and-children-using-endoscopic-approaches
#11
REVIEW
Manabu Okawada, Ciro Esposito, Maria Escolino, Alessandra Farina, Mariapina Cerulo, Francesco Turrà, Atsuyuki Yamataka
Vesicoureteral reflux (VUR) represents one of the most significant risk factors for acute pyelonephritis in children. Endoscopic treatment of VUR dates back to 1981 when Matouschek first described injection of the ureteral orifice in an attempt to correct VUR. In addition, also Politano and colleagues and McDonald described successful correction of reflux using endoscopic techniques. After these reports subureteral Teflon injection (STING) came to be appreciated as a viable new way to less invasively correct one of the most common pediatric urologic problems...
October 2016: Translational pediatrics
https://www.readbyqxmd.com/read/27865246/renal-tuberculosis-presenting-as-acute-pyelonephritis-a-rarity
#12
Ajay Kumar Verma, Ashwini Kumar Mishra, Manoj Kumar, Surya Kant, Anubhuti Singh, Ajay Singh
One of the major health problems faced particularly by the developing world since ages is that of tuberculosis (TB). Genito-urinary tuberculosis (GUTB) is the second most common extrapulmonary TB, with kidney being the most frequent site of infection. Due to the diverse and atypical clinical manifestations of urinary TB, the disease is easy to misdiagnose. The diagnosis of renal TB should be suspected in a nonspecific bacterial cystitis associated with a therapeutic failure or a sterile pyuria and a past history of pulmonary TB with important radiologic findings, particularly with the help of CT scan...
July 2016: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/27824770/microangiopathic-hemolytic-anemia-due-to-malignancy-in-pregnancy
#13
Sarah K Happe, Amanda C Zofkie, David B Nelson
BACKGROUND: Microangiopathic disorders during pregnancy remain a diagnostic challenge because these conditions often imitate more common obstetric diseases. CASE: A 31-year-old multigravid woman delivered at term with a postpartum course complicated by laboratory indices consistent with hemolysis, elevated liver enzymes, and low platelet count syndrome. After clinical recovery, she was readmitted 2 weeks after delivery with presumptive pyelonephritis. Persistent hemolysis and worsening thrombocytopenia suggested a diagnosis of thrombotic microangiopathy, which did not respond to plasma exchange...
December 2016: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27824318/concurrent-diffuse-pyelonephritis-and-prostatitis-discordant-findings-on-sequential-fdg-pet-ct-and-67ga-spect-ct-imaging
#14
Robert Lucaj, Dwight M Achong
A 45-year-old man underwent FDG PET/CT for initial imaging evaluation of recurrent Escherichia coli urinary tract infections, which demonstrated no significant FDG uptake in either kidney and subtle FDG uptake in the right prostate lobe. Subsequent Ga SPECT/CT demonstrated abnormal intense gallium uptake throughout the right kidney and entire prostate gland, clearly discordant with PET/CT findings and consistent with unexpected concurrent pyelonephritis and prostatitis. Although FDG has effectively replaced Ga in everyday clinical practice, the current case serves as a reminder that there is still a role for Ga in the evaluation of genitourinary infections...
October 12, 2016: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/27821396/morphine-induced-hearing-loss
#15
Leire Leache, Irene Aquerreta, Libe Moraza, Ana Ortega
PURPOSE: A case of severe bilateral sensorineural hearing loss associated with oral morphine is reported. SUMMARY: A 52-year-old Spanish man was admitted to the intensive care unit with a Glasgow Coma Scale score of 3, a fever, and sudden hearing loss with tinnitus in both ears. His medical history included type 2 diabetes mellitus, depression, sleep disorder, and hypertension. The patient also had pyelonephritis in 2011 and pulmonary embolism in 2014, requiring the placement of an inferior vena cava filter and chronic anticoagulation...
November 15, 2016: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/27814677/a-single-center-observational-study-on-emergency-department-clinician-non-adherence-to-clinical-practice-guidelines-for-treatment-of-uncomplicated-urinary-tract-infections
#16
Catherine Zatorski, Mark Zocchi, Sara E Cosgrove, Cynthia Rand, Gillian Brooks, Larissa May
BACKGROUND: The Emergency Department (ED) is a frequent site of antibiotic use; poor adherence with evidence-based guidelines and broad-spectrum antibiotic overuse is common. Our objective was to determine rates and predictors of inappropriate antimicrobial use in patients with uncomplicated urinary tract infections (UTI) compared to the 2010 International Clinical Practice Guidelines (ICPG). METHODS: A single center, prospective, observational study of patients with uncomplicated UTI presenting to an urban ED between September 2012 and February 2014 that examined ED physician adherence to ICPG when treating uncomplicated UTIs...
November 4, 2016: BMC Infectious Diseases
https://www.readbyqxmd.com/read/27806709/benefits-and-harms-of-screening-for-and-treatment-of-asymptomatic-bacteriuria-in-pregnancy-a-systematic-review
#17
Konstanze Angelescu, Barbara Nussbaumer-Streit, Wiebke Sieben, Fülöp Scheibler, Gerald Gartlehner
BACKGROUND: Most European and North American clinical practice guidelines recommend screening for asymptomatic bacteriuria (ASB) as a routine pregnancy test. Antibiotic treatment of ASB in pregnant women is supposed to reduce maternal upper urinary tract infections (upper UTIs) and preterm labour. However, most studies supporting the treatment of ASB were conducted in the 1950s to 1980s. Because of subsequent changes in treatment options for ASB and UTI, the applicability of findings from these studies has come into question...
November 2, 2016: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/27798778/hospitalizations-for-chronic-conditions-among-indigenous-australians-after-medication-copayment-reductions-the-closing-the-gap-copayment-incentive
#18
Amal N Trivedi, Ross Bailie, Jodie Bailie, Alex Brown, Margaret Kelaher
BACKGROUND: To close health disparities between Indigenous and non-Indigenous Australians, the Australian government in 2010 reduced medication copayments for Indigenous Australians living with, or at risk of, a chronic disease. Patients were registered for this incentive by their general practitioner. OBJECTIVE: To assess rates of hospitalizations for chronic conditions among Indigenous Australians before and after copayment reductions. DESIGN: Observational time-trend study of hospitalizations for chronic conditions sensitive to medication adherence...
October 31, 2016: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/27798510/infections-in-de-novo-kidney-transplant-recipients-treated-with-the-rankl-inhibitor-denosumab
#19
Marco Bonani, Diana Frey, Olivier de Rougemont, Nicolas J Mueller, Thomas F Mueller, Nicole Graf, Rudolf P Wüthrich
BACKGROUND: Infections are a major cause of morbidity and mortality in kidney allograft recipients. In this posthoc analysis of a randomized clinical trial which tested the effect of denosumab on bone mineral density we assessed the impact of this drug on the incidence and severity of infections in the first year after kidney transplantation. METHODS: In this clinical trial we randomized 90 de novo kidney transplant recipients shortly after transplantation to either denosumab on top of standard treatment (calcium and vitamin D) (n=46), or to standard treatment alone (n=44)...
October 28, 2016: Transplantation
https://www.readbyqxmd.com/read/27795729/protective-effect-of-yinhua-miyanling-tablet-on-lipopolysaccharide-induced-inflammation-through-suppression-of-nlrp3-caspase-1-inflammasome-in-human-peripheral-blood-mononuclear-cells
#20
Jingying Sai, Lingxin Xiong, Jingtong Zheng, Chuangui Liu, Yanjiao Lu, Guoqiang Wang, Yawei Wang, Ting Wang, Xuewa Guan, Fang Chen, Keyong Fang, Chao Zhang, Junying Lu, Xiaotian Zhang, Hailin Zhu, Fang Wang
Yinhua Miyanling Tablet (YMT), the Chinese formula, has long been administrated in clinical practice for the treatment of acute pyelonephritis and acute urocystitis. In the current study, we aimed to investigate the anti-inflammatory effect of YMT in vitro and to evaluate the association between anti-inflammation and innate immune response. Human peripheral blood mononuclear cells (PBMCs) were isolated using Ficoll density gradient centrifugation and then were stimulated by Lipopolysaccharide (LPS). The differential gene expression of inflammation-related genes after drug administration was assessed using PCR array, and the protein levels of differential genes were measured by ELISA and Western blot...
2016: Evidence-based Complementary and Alternative Medicine: ECAM
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