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https://www.readbyqxmd.com/read/28199453/not-recluse-a-mnemonic-device-to-avoid-false-diagnoses-of-brown-recluse-spider-bites
#1
William V Stoecker, Richard S Vetter, Jonathan A Dyer
No abstract text is available yet for this article.
February 15, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28194160/highlights-in-the-knowledge-of-brown-spider-toxins
#2
REVIEW
Daniele Chaves-Moreira, Andrea Senff-Ribeiro, Ana Carolina Martins Wille, Luiza Helena Gremski, Olga Meiri Chaim, Silvio Sanches Veiga
Brown spiders are venomous arthropods that use their venom for predation and defense. In humans, bites of these animals provoke injuries including dermonecrosis with gravitational spread of lesions, hematological abnormalities and impaired renal function. The signs and symptoms observed following a brown spider bite are called loxoscelism. Brown spider venom is a complex mixture of toxins enriched in low molecular mass proteins (4-40 kDa). Characterization of the venom confirmed the presence of three highly expressed protein classes: phospholipases D, metalloproteases (astacins) and insecticidal peptides (knottins)...
2017: Journal of Venomous Animals and Toxins Including Tropical Diseases
https://www.readbyqxmd.com/read/28076265/nonbacterial-causes-of-lymphangitis-with-streaking
#3
Brandon E Cohen, Arielle R Nagler, Miriam Keltz Pomeranz
BACKGROUND: Lymphangitic streaking, characterized by linear erythema on the skin, is most commonly observed in the setting of bacterial infection. However, a number of nonbacterial causes can result in lymphangitic streaking. We sought to elucidate the nonbacterial causes of lymphangitic streaking that may mimic bacterial infection to broaden clinicians' differential diagnosis for patients presenting with lymphangitic streaking. METHODS: We performed a review of the literature, including all available reports pertaining to nonbacterial causes of lymphangitic streaking...
November 2016: Journal of the American Board of Family Medicine: JABFM
https://www.readbyqxmd.com/read/28017694/pitfalls-to-avoid-when-using-phage-display-for-snake-toxins
#4
Andreas Hougaard Laustsen, Line Præst Lauridsen, Bruno Lomonte, Mikael Rørdam Andersen, Brian Lohse
Antivenoms against bites and stings from snakes, spiders, and scorpions are associated with immunological side effects and high cost of production, since these therapies are still derived from the serum of hyper-immunized production animals. Biotechnological innovations within envenoming therapies are thus warranted, and phage display technology may be a promising avenue for bringing antivenoms into the modern era of biologics. Although phage display technology represents a robust and high-throughput approach for the discovery of antibody-based antitoxins, several pitfalls may present themselves when animal toxins are used as targets for phage display selection...
December 23, 2016: Toxicon: Official Journal of the International Society on Toxinology
https://www.readbyqxmd.com/read/28017625/first-case-of-dress-syndrome-attributed-to-a-spider-bite
#5
Alexia Eyraud, Lucile Boursault, Anne-Sophie Darrigade, Alain Taieb, Brigitte Milpied
No abstract text is available yet for this article.
December 22, 2016: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/27846029/nonhealing-wounds-caused-by-brown-spider-bites-application-of-hyperbaric-oxygen-therapy
#6
Amir Hadanny, Gregory Fishlev, Yair Bechor, Oshra Meir, Shai Efrati
BACKGROUND: Bites by Loxosceles spiders (also known as recluse spiders or brown spiders) can cause necrotic ulcerations of various sizes and dimensions. The current standard of care for brown spider bites includes analgesics, ice, compression, elevation, antihistamines, and surgical debridement. Hyperbaric oxygen therapy (HBOT) in the treatment of brown spider bites has been administered in the early stage of ulceration, or 2 to 6 days after the bite. Unfortunately, the diagnosis of spider bite-related ulcers is often delayed and weeks or months may elapse before HBOT is considered...
December 2016: Advances in Skin & Wound Care
https://www.readbyqxmd.com/read/27798387/a-15-year-old-boy-with-progressive-weakness-after-a-spider-bite
#7
Emily J Ciccone, Robert B Christian, Daniel M Lercher, Kenya McNeal-Trice, Benny L Joyner
No abstract text is available yet for this article.
October 18, 2016: Clinical Pediatrics
https://www.readbyqxmd.com/read/27749012/injury-trends-from-envenoming-in-australia-2000-2013
#8
R E Welton, D J Williams, D Liew
BACKGROUND: Accidental injury is a major public health problem in developed countries with 20 years elapsed since a national overview of venomous bites undertaken in Australia. AIM: Provide the first contemporary epidemiological insight into venomous injuries based on demographics and geography nationally in Australia in the period 2000-2013. METHODS: An analysis of national hospitalisation and mortality data was undertaken to examine the incidence of injury and death due to envenoming in Australia...
February 2017: Internal Medicine Journal
https://www.readbyqxmd.com/read/27699754/-tarantism-in-spain-in-the-eighteen-century-latrodectism-and-suggestion
#9
REVIEW
I Corral-Corral, C Corral-Corral
INTRODUCTION: Tarantism is the disease caused by the bite of the tarantula, in which the music tarantella triggers an involuntary dance. It is known in Italy since the sixteenth century. AIM: To analyze the tarantism reported in Spain at the end of the eighteenth century, with special attention to its neurological aspects, and to propose its medical and psychopathological explanation. DEVELOPMENT: An epidemic of people affected by the tarantula bite occurred in Spain in 1782...
October 16, 2016: Revista de Neurologia
https://www.readbyqxmd.com/read/27692235/-cutaneous-loxoscelism-about-an-exceptional-observation-of-9-consecutive-cases
#10
F Boissiere, R Masson, S Fluieraru, J Vitse, L Dessena, M Lefevre, F Bekara, C Herlin
INTRODUCTION: Loxosceles spiders are ubiquitous and responsible for many cases of envenomation in the world. The kind rufescens is present in the Provence and Occitan regions in France. During the summer 2015, we faced many Loxosceles rufescens cases of bites having led to extensive integumental necrosis whose features and singular evolution seems important to report. MATERIAL AND METHODS: We report the cases of nine patients who experienced a spider bite in the summer of 2015 in the Languedoc Roussillon...
December 2016: Annales de Chirurgie Plastique et Esthétique
https://www.readbyqxmd.com/read/27685512/an-interesting-case-of-intracerebral-mrsa
#11
Robert Estridge, Shawnelle Contini
This article describes a patient whose intracerebral MRSA may have been caused by a spider bite to the thigh 2 months earlier. The patient's headache, nausea, and vomiting initially were thought to be caused by a high-grade glioma. Most brain abscesses have otogenic sources and are not from distant hematogenous spread. Although systemic antibiotics help with symptomatology, surgical eradication (when feasible) followed by IV antibiotics, provides definitive treatment.
October 2016: JAAPA: Official Journal of the American Academy of Physician Assistants
https://www.readbyqxmd.com/read/27651958/spider-bite-a-rare-case-of-acute-necrotic-arachnidism-with-rapid-and-fatal-evolution
#12
Mario Pezzi, Anna Maria Giglio, Annamaria Scozzafava, Orazio Filippelli, Giuseppe Serafino, Mario Verre
The spider bites are quite frequent and often resolve quickly without leaving outcomes; only some species are capable of causing necrotic and systematic lesions in humans. Among them, we should mention the genus Loxosceles. The venom released from the spider bite of Loxosceles species is composed of proteins, enzymes, and nonenzymatic polypeptides. The phospholipase D family was identified as the active component of the venom. This family of enzymes is responsible for the local and systemic effects observed in loxoscelism...
2016: Case Reports in Emergency Medicine
https://www.readbyqxmd.com/read/27604938/arthropods-bite-like-a-spider-sting-like-a-scorpion
#13
LETTER
Reza Afshari
No abstract text is available yet for this article.
8, 2016: Nature
https://www.readbyqxmd.com/read/27579754/acute-generalized-exanthematous-pustulosis-associated-with-spider-bite
#14
Laura de Mattos Milman, Giana Paula Müller, Paulo Ricardo Martins Souza, Aline Barcellos Grill, Deise Louise Bohn Rhoden, Carlos Augusto Mello-da-Silva, Gerson Vettorato
Acute generalized exanthematous pustulosis (AGEP) is an acute febrile rash, usually induced by drugs, which recently has been linked to spider bite. We report a case of a male patient, 48 years old, with an erythematous rash accompanied by fever and small non-follicular pustules. He reported previous pain in the buttock with the onset of a necrotic plaque. The lesion was compatible with spider bite of the genus Loxosceles. According to the EuroSCAR group instrument, the patient scored +10 indicating definite diagnosis of AGEP...
July 2016: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/27563734/potential-implications-for-designing-drugs-against-the-brown-spider-venom-phospholipase-d
#15
Daniele Chaves-Moreira, Fábio Rogério de Moraes, Ícaro Putinhon Caruso, Olga Meiri Chaim, Andrea Senff-Ribeiro, Anwar Ullah, Luciane Sussuchi da Silva, Jorge Chahine, Raghuvir K Arni, Silvio Sanches Veiga
Loxoscelism refers to the clinical symptoms that develop after brown spider bites. Brown spider venoms contain several phospholipase-D isoforms, which are the main toxins responsible for both the cutaneous and systemic effects of loxoscelism. Understanding of the phospholipase-D catalytic mechanism is crucial for the development of specific treatment that could reverse the toxic effects caused by the spider bite. Based on enzymatic, biological, structural, and thermodynamic tests, we show some features suitable for designing drugs against loxoscelism...
August 26, 2016: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/27496061/description-of-loxtox-protein-family-and-identification-of-a-new-group-of-phospholipases-d-from-loxosceles-similis-venom-gland
#16
Arthur Estanislau Dantas, A O Carmo, Carolina Campolina Rebello Horta, Hortênsia Gomes Leal, Bárbara Bruna Ribeiro Oliveira-Mendes, Ana Paula Vimieiro Martins, Carlos Chávez-Olórtegui, Evanguedes Kalapothakis
Envenoming resulting from Loxosceles spider bites (loxoscelism) is a recognized public health problem in Brazil. However, the pathophysiology of loxoscelism caused by L. similis bites, which is widespread in Brazil, remains poorly understood. In the present work, the RNA sequencing (RNA-Seq - Next Generation sequencing - NGS) of the L. similis venom gland was performed to identify and analyze the sequences of the key component phospholipase D. The sequences were aligned based on their classical domains, and a phylogenetic tree was constructed...
September 15, 2016: Toxicon: Official Journal of the International Society on Toxinology
https://www.readbyqxmd.com/read/27440851/rare-case-of-dermonecrosis-caused-by-a-recluse-spider-bite-in-europe
#17
Monique Cachia, Liam Mercieca, Charles Mallia Azzopardi, Michael J Boffa
Spider poisoning is rare in Europe, with very few reported cases in the literature. Recluse spider (genus Loxosceles) bites may lead to cutaneous and systemic manifestations known as loxoscelism. We report the second known case of spider bite poisoning in Malta caused by Loxosceles rufescens (Mediterranean recluse spider). A young adult female presented with localised erythema and pain on her left thigh after a witnessed spider bite. Over a few days, the area developed features of dermonecrosis together with systemic symptoms, including fever, fatigue and a generalised erythematous eruption...
July 20, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27363053/intervention-program-for-nursing-staff-regarding-approach-to-a-patient-with-spider-phobia-and-or-bite
#18
REVIEW
Mahfouz Ahmad Al-Agroudi, Salwa Abdalla Mohammad Ahmed, Tosson A Morsy
Spider bites are uncommon medical events, since there are limited number of spiders world-wide with fangs strong enough to pierce human skin, and most spiders bite humans only as a final defense when being crushed between skin and another object. Thus, most lesions attributed to spider bites are caused by some other etiology. The spiders that can cause medically significant bites include widow and false widow spiders (worldwide), recluse spiders (mostly North and South America), Australian funnel web spiders (eastern coastal Australia) and Phoneutria spiders (Brazil)...
April 2016: Journal of the Egyptian Society of Parasitology
https://www.readbyqxmd.com/read/27351646/recognizing-and-treating-patients-with-envenomations
#19
John B Hurt, Kristopher R Maday
Venomous spiders and snakes are found throughout the United States, and clinicians often encounter patients with suspected spider or snakebites. Due to the significant morbidity and mortality that can be related to a particular envenomation, clinicians must be able to recognize the species of spiders and snakes that are capable of delivering a venomous bite. Through proper species identification, recognition of the specific signs and symptoms that specific venom produces, and understanding the treatment guidelines for the envenomation, clinicians can properly diagnosis, treat, and manage patients with venomous bites...
July 2016: JAAPA: Official Journal of the American Academy of Physician Assistants
https://www.readbyqxmd.com/read/27323529/spider-bites-more-than-meets-the-eye
#20
Angela R Olerich, Keith Stelter, Susan Laabs
No abstract text is available yet for this article.
May 2016: Minnesota Medicine
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