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Lymphedema surgery

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https://www.readbyqxmd.com/read/28105873/loco-regional-morbidity-after-breast-conservation-and-axillary-lymph-node-dissection-for-early-breast-cancer-with-or-without-regional-nodes-radiotherapy-perspectives-in-modern-breast-cancer-treatment-the-skagen-trial-1-is-active
#1
Hanne Melgaard Nielsen, Rasmus Blechingberg Friis, Søren Linnet, Birgitte Vrou Offersen
BACKGROUND: Axillary lymph node dissection (ALND) and adjuvant radiotherapy (RT) in early breast cancer are associated with a risk of morbidity, including lymphedema and impaired shoulder mobility. The aim of this study was to evaluate loco-regional morbidity after breast conserving surgery (BCS), ALND, taxane-based chemotherapy and whole breast irradiation (WBI) with or without regional nodes RT. MATERIAL AND METHODS: Eligible patients had BCS and ALND from 2007 to 2012 followed by adjuvant taxane-based chemotherapy and if indicated, trastuzumab and endocrine treatment...
January 20, 2017: Acta Oncologica
https://www.readbyqxmd.com/read/28094037/identifying-risk-factors-for-occult-lower-extremity-lymphedema-using-computed-tomography-in-patients-undergoing-lymphadenectomy-for-gynecologic-cancers
#2
Miseon Kim, Dong Hoon Suh, Eun Joo Yang, Myong Cheol Lim, Jin Young Choi, Kidong Kim, Jae Hong No, Yong-Beom Kim
OBJECTIVE: To identify risk factors for lower extremity lymphedema (LEL) using computed tomographic (CT) scan in patients undergoing lymphadenectomy for gynecologic cancers. METHODS: We retrospectively reviewed 511 consecutive gynecologic cancer patients undergoing lymphadenectomy. Mean difference (3.77±3.14mm) of subcutaneous layer thicknesses between preoperative and postoperative 1-year CT scans of 106 patients with clinical LEL was used as an objective criterion for regrouping all the patients into those with mean difference >3...
January 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/28054496/tailoring-exercise-interventions-to-comorbidities-and-treatment-induced-adverse-effects-in-patients-with-early-stage-breast-cancer-undergoing-chemotherapy-a-framework-to-support-clinical-decisions
#3
Marike van der Leeden, Rosalie J Huijsmans, Edwin Geleijn, Mariëtte de Rooij, Inge R Konings, Laurien M Buffart, Joost Dekker, Martijn M Stuiver
PURPOSE: Delivery of exercise interventions to patients with early-stage breast cancer undergoing chemotherapy requires complex clinical decisions. The purpose of this study was to develop a framework to support clinical decisions for tailoring exercise interventions to common comorbidities and cancer treatment-induced adverse effects. METHOD: Tailored exercise prescriptions were developed in four steps, following the i3-S strategy. All steps were based on current best available evidence, complemented with expert opinions...
January 5, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28052379/supermicrosurgical-lymphaticovenous-anastomosis-for-a-patient-with-breast-lymphedema-secondary-to-breast-cancer-treatment
#4
Guido Giacalone, Takumi Yamamoto
Breast lymphedema (BLE) has been reported as a complication following breast cancer treatment. As for extremity lymphedema treatment, supermicrosurgical lymphaticovenous anastomosis (LVA) is considered an option for the treatment of progressive BLE refractory to conservative treatments, but no case has been reported so far. We report the first case of BLE successfully treated with supermicrosurgical LVA. A 55-year-old female presented with left BLE after breast conserving surgery and axillary lymph node dissection and adjuvant radiotherapy...
January 3, 2017: Microsurgery
https://www.readbyqxmd.com/read/28027235/establishment-of-an-acquired-lymphedema-model-in-the-mouse-hindlimb-technical-refinement-and-molecular-characteristics
#5
Daisuke Iwasaki, Yuhei Yamamoto, Naoki Murao, Akihiko Oyama, Emi Funayama, Hiroshi Furukawa
BACKGROUND: The pathophysiology of secondary lymphedema remains poorly understood. This study aimed to establish a consistent mouse hindlimb lymphedema model for further investigation of the mechanism and treatment of lymphedema. METHODS: The authors developed a novel postsurgical lymphedema model in the mouse hindlimb by modifying previously described methods. Lymphedema in the hindlimb was created by removing both the inguinal and popliteal lymph nodes together with the surrounding fat pads, followed by silicone splint placement in the inguinal region...
January 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28025009/peri-operative-care-for-patients-undergoing-lymphaticovenular-anastomosis-a-systematic-review
#6
REVIEW
Harm Winters, Hanneke J P Tielemans, Philippe N Sprangers, Dietmar J O Ulrich
BACKGROUND: Lymphaticovenular anastomosis (LVA) is a supermicrosurgical procedure that involves the anastomosis of a functional lymphatic channel to a venule. Although peri-operative care might be an important contributor to the success of this technique, evidence about optimal peri-operative care seems limited. This review aims to summarize the peri-operative methods used by authors reporting on LVA. METHODS: A systematic search of the literature was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines...
November 27, 2016: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/28012086/radiation-therapy-targets-and-the-risk-of-breast-cancer-related-lymphedema-a-systematic-review-and-network-meta-analysis
#7
REVIEW
Simona F Shaitelman
PURPOSE: New indications have been found for regional nodal irradiation (RNI) in breast cancer treatment, yet the relationship of RNI and lymphedema risk is uncertain. We sought to determine the association of RNI and lymphedema. METHODS: We searched MEDLINE, EMBASE, and Scopus for articles in English on humans published from 1995 to 2015, using search terms breast neoplasm, treatment, and morbidity. Two investigators independently selected articles and extracted information, including manuscripts reporting incidence of lymphedema by radiation targets...
December 23, 2016: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/27990192/long-term-results-of-innovative-procedure-in-surgical-management-of-chronic-lymphedema
#8
Seyed R Mousavi
BACKGROUND: Lymphedema is the result of impaired lymphatic drainage by the affected organ. This abnormality can be primary or secondary. Different operative approaches have been introduced to treat chronic lymphedema. MATERIALS AND METHODS: This retrospective study included 816 patients who were diagnosed with chronic lower extremity lymphedema and did not respond to non-operative management for at least six months. Data was collected over 25 years, between March 1987 and March 2013...
2016: Open Orthopaedics Journal
https://www.readbyqxmd.com/read/27987230/the-lymphatic-superficial-circumflex-iliac-vessels-deep-branch-perforator-flap-a-new-preventive-approach-to-lower-limb-lymphedema-after-groin-dissection-preliminary-evidence
#9
Stefano Gentileschi, Maria Servillo, Giorgia Garganese, Simona Fragomeni, Francesca De Bonis, Alessandro Cina, Giovanni Scambia, Marzia Salgarello
OBJECTIVE: Groin dissection is the procedure with the highest risk of lower limb lymphedema.As lymph stasis causes irreversible alterations to the limb over time,therapies should be administered in early stages,or better yet, lymphatic drainage impairment should be prevented.We developed a new preventive approach to lymphedema after groin dissection, and we report our preliminary experience. PATIENTS AND METHODS: We enrolled 5 patients undergoing bilateral groin dissection for vulvar cancer...
December 17, 2016: Microsurgery
https://www.readbyqxmd.com/read/27984376/long-term-morbidity-and-quality-of-life-in-cervical-cancer-survivors-a-multicenter-comparison-between-surgery-and-radiotherapy-as-primary-treatment
#10
Marloes Derks, Luc R C W van Lonkhuijzen, Rinske M Bakker, Anne M Stiggelbout, Cornelis D de Kroon, Henrike Westerveld, Jan Paul W R Roovers, Gemma G Kenter, Moniek M Ter Kuile
OBJECTIVE: To compare long-term morbidity and quality of life after primary surgery or primary radiotherapy for stage IB/II cervical cancer. METHODS: A cross-sectional study was performed. Patients treated for stage IB/II cervical cancer between 2000 and 2010 were approached to participate. Primary treatment consisted of radical hysterectomy with pelvic lymphadenectomy (RHL), for selected cases followed by adjuvant (chemo-)radiotherapy, or primary (chemo)radiotherapy (PRT)...
December 15, 2016: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/27976365/heterotopic-vascularized-lymph-node-transfer-to-the-medial-calf-without-a-skin-paddle-for-restoration-of-lymphatic-function-proof-of-concept
#11
Mark L Smith, Bianca J Molina, Erez Dayan, Diane S Saint-Victor, Julie N Kim, Eugene S Kahn, Alexander Kagen, Joseph H Dayan
BACKGROUND: The use of heterotopic vascularized lymph node transfer (HVLNT) for the treatment of lower extremity lymphedema is still evolving. Current techniques, either place the lymph nodes in the thigh without a skin paddle or at the ankle requiring an unsightly and often bulky skin paddle for closure. We explored the feasibility of doing a below-knee transfer without a skin paddle using the medial sural vessels as recipient vessels and report our experience in 21 patients. METHODS: A retrospective review of all patients who underwent HVLNT to the medial calf was performed...
December 15, 2016: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27974914/modulating-the-extension-of-axillary-lymphadenectomy-for-early-stage-breast-cancer
#12
REVIEW
M Plesca, C Bordea, B El Houcheimi, E Ichim, A Blidaru
Axillary lymph node evaluation remains essential in breast cancer surgery, first as a prognostic factor, because it indicates the degree of dissemination of the disease to the main lymphatic drainage basin of the breast, and, on the other hand, as an element of preventing the local relapse. In the era of the sentinel lymph node, complete axillary lymphadenectomy, considered valuable until recently, but as therapeutic and diagnostic, has become an intervention performed increasingly rare in selected cases. Axillary lymphatic tissue resections are accompanied by morbidity (lymphedema, paresthesia, limitations of arm movement) and symptom magnitude is proportional to the extension of the intervention...
January 2016: Journal of Medicine and Life
https://www.readbyqxmd.com/read/27943281/latissimus-dorsi-flap-with-vascularized-lymph-node-transfer-for-lymphedema-treatment-technique-outcomes-indications-and-review-of-literature
#13
Amir Inbal, Chad M Teven, David W Chang
BACKGROUND AND OBJECTIVES: One of the surgical treatment options for lymphedema is vascularized lymph node transfer (VLNT). We present our experience with latissimus dorsi (LD) flap based VLNT for lymphedema treatment. METHODS: We reviewed 14 consecutive patients treated with pedicled or free LD VLNT between 2014 and 2016 for recalcitrant upper or lower extremity lymphedema. Seven patients underwent lymphovenous bypass in addition to LD VLNT. Limb volume and quality of life scores using the Lymphedema Life Impact Scale (LLIS) were analyzed for quantitative and qualitative assessment...
December 12, 2016: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27942023/lymph-node-transplantation-decreases-swelling-and-restores-immune-responses-in-a-transgenic-model-of-lymphedema
#14
Jung-Ju Huang, Jason C Gardenier, Geoffrey E Hespe, Gabriela D García Nores, Raghu P Kataru, Catherine L Ly, Inés Martínez-Corral, Sagrario Ortega, Babak J Mehrara
INTRODUCTION: Secondary lymphedema is a common complication of cancer treatment and recent studies have demonstrated that lymph node transplantation (LNT) can decrease swelling, as well as the incidence of infections. However, although these results are exciting, the mechanisms by which LNT improves these pathologic findings of lymphedema remain unknown. Using a transgenic mouse model of lymphedema, this study sought to analyze the effect of LNT on lymphatic regeneration and T cell-mediated immune responses...
2016: PloS One
https://www.readbyqxmd.com/read/27932150/real-time-intraoperative-fluorescent-lymphography-a-new-technique-for-lymphatic-sparing-surgery
#15
G Ietto, F Amico, G Soldini, C Chiappa, M Franchin, D Iovino, A Romanzi, G Saredi, E Cassinotti, L Boni, M Tozzi, G Carcano
BACKGROUND: Many surgical procedures can produce persistent lymphorrhea, lymphoceles, and lymphedema after lymph node and lymph vessel damage. Appropriate visualization of the lymphatic system is challenging. Indocyanine green (ICG) is a well-known nontoxic dye for lymphatic flow evaluation. ICG fluorescence-guided lymphography has emerged as a promising technique for intraoperative lymphatic mapping. OBJECTIVE: Our goal was to develop a high spatial resolution, real-time intraoperative imaging technique to avoid or recognize early deep lymphatic vessel damage...
November 2016: Transplantation Proceedings
https://www.readbyqxmd.com/read/27928868/effectiveness-of-decongestive-lymphatic-therapy-in-patients-with-lymphedema-resulting-from-breast-cancer-treatment-regardless-of-previous-lymphedema-treatment
#16
Mehtap Bozkurt, Lynn J Palmer, Ying Guo
Decongestive lymphatic therapy (DLT) has gained wide acceptance as an effective treatment for patients with lymphedema resulting from breast cancer treatment. It is unclear whether DLT is effective for patients with lymphedema who have received lymphedema treatment previously. Our purpose was to compare the effectiveness of DLT in patients who had received lymphedema treatment previously with those who had never received treatment. We retrospectively reviewed the medical records of 98 patients who received outpatient lymphedema therapy for upper extremity lymphedema following surgery...
December 7, 2016: Breast Journal
https://www.readbyqxmd.com/read/27918865/evidence-based-practice-in-the-management-of-lower-limb-lymphedema-after-gynecological-cancer
#17
Lisandra Fossari Iwersen, Fabiana Flores Sperandio, Ariana Machado Toriy, Marina Palú, Clarissa Medeiros da Luz
PURPOSE: Lower limb lymphedema (LLL) is characterized as a physical-functional chronic complication that impacts the quality of life of women who have gone through treatment for gynecological cancer. The present study aims to check the conservative treatments available for lymphedema after gynecological cancer in the context of evidence-based practice. METHODS: The selection criteria included papers from May 1993 discussing treatment protocols used in LLL after treatment for gynecological cancer...
January 2017: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/27906440/supramicrosurgical-lymphatico-venular-anastomosis-lva-in-treating-lymphoedema-36-months-preliminary-report
#18
P Gennaro, G Gabriele, M Mihara, K Kikuchi, C Salini, I Aboh, F Cascino, G Chisci, C Ungari
OBJECTIVE: Lymphoedema of the extremities is a widespread pathological condition that mostly occurs as a complication of cancer resections, especially in women. Conventional therapy refers to conservative and physiotherapeutic approaches. Surgical strategies have been widely reported in the literature and are still challenging. Part of this literature focuses on the supra microsurgical lymphaticovenular anastomosis (LVA) technique. LVA is characterized by a high success rate, minimal invasivity and broad indications...
November 2016: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/27866037/preoperative-preparation-of-a-patient-with-grade-ii-leg-lymphedema-for-his-third-hip-replacement-surgery
#19
Maria de Fátima Guerreiro Godoy, Livia Maria Pereira de Godoy, Renata Lopes Pinto, Jose Maria Pereira de Godoy
INTRODUCTION: The treatment of lymphedema remains a challenge to modern medicine, due to the characteristics of the disease. CASE PRESENTATION: Report on the case of a 75-year-old patient with lower limb lymphedema for treatment prior to surgery. At age 45, he made the first hip replacement surgery in the left leg. One year later he performed the same surgery on the right leg. At that time his legs had slight ankle edema mainly of the left leg and the entire left leg was affected by lymphedema...
2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/27865752/reconstruction-of-massive-localized-lymphedema-of-the-scrotum-results-complications-and-quality-of-life-improvements
#20
Eric Wisenbaugh, Dena Moskowitz, Joel Gelman
OBJECTIVE: To review the surgical technique, outcomes and complications of surgical excision of massive localized lymphedema of the scrotum, and to determine changes in weight and quality of life after excision. MATERIALS AND METHODS: A retrospective review was performed for all patients who have undergone excision of MLL of the scrotum at our institution between 2008 and 2014. Standard baseline characteristics, complications, pre- and postoperative weight and quality of life data were recorded...
November 16, 2016: Urology
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