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https://www.readbyqxmd.com/read/28107758/retroperitoneal-unicentric-castleman-s-disease-a-case-report
#1
Nihed Abdessayed, Ahlem Bdioui, Houssem Ammar, Rahul Gupta, Nozha Mhamdi, Marwa Guerfela, Moncef Mokni
INTRODUCTION: Castleman's disease (CD) is an angio-follicular lymph node hyperplasia presenting as a localized or a systemic disease masquerading malignancy. The most common sites of CD are mediastinum, neck, axilla and pelvis. Unicentric CD in the peripancreatic region is very rare. PRESENTATION OF CASE: We report a case of the 34-year-old lady presenting with epigastric pain for 3 months. Abdominal imaging revealed a retroperitoneal mass arising from the pancreas suspected to be neuroendocrine tumor...
January 5, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28107716/occurrence-speciation-and-transportation-of-heavy-metals-in-9-coastal-rivers-from-watershed-of-laizhou-bay-china
#2
Li Xu, Tieyu Wang, Jihua Wang, Anxiang Lu
The occurrence, speciation and transport of heavy metals in 9 coastal rivers from watershed of Laizhou Bay were investigated. The largest dissolved concentrations of Cd, Cu and Zn in water were 6.26, 2755.00, 2076.00 μg/L, respectively, much higher than several drinking water guidelines. The greatest concentrations of Cu, Zn, Cr, Ni, Pb and Cd in sediments were 1462, 1602, 196, 67.2, 63.5 and 1.41 mg/kg, dw, respectively. Correlation and principal component analysis was also conducted to determine the extent between the concentrations of metals in water and sediment, as well as relevant parameters...
January 9, 2017: Chemosphere
https://www.readbyqxmd.com/read/28107568/oral-immunoglobulin-treatment-improved-intestinal-permeability-in-children-with-active-crohn-s-disease
#3
Tommy Sundqvist, Lars Stenhammar, Bo Tjellström, Karl-Eric Magnusson, Tony Forslund, Lotta Högberg
AIM: Crohn's disease (CD) is a chronic mucosal inflammation that affects the intestinal barrier function, for example by altering the intestinal permeability. This pilot clinical study investigated the impact of oral human immunoglobulin (OHIG) treatment on permeability characteristics in children with active luminal Crohn's disease. METHODS: The study was performed at the Department of Paediatrics, Norrköping Hospital, Sweden. Intestinal permeability was studied in three boys aged 13, 15 and 18 years with active CD, before and after a six-week treatment programme with OHIG, using different-sized polyethylene glycols the test molecules...
January 20, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28107441/fine-mapping-and-candidate-gene-analysis-of-the-tiller-suppression-gene-ts1-in-rice
#4
Lei Liu, Fen Meng, Yonggang He, Menghao Zhu, Yanhao Shen, Zhihong Zhang
Tiller number is one of the key factors that influences rice plant type and yield components. In this study, an EMS-induced rice tiller suppression mutant ts1 was characterized. Morphological and histological observations revealed that, in the ts1 plants, the tiller buds were abnormally formed and therefore cannot outgrow into tillers. With an F2 population derived from a cross between ts1 and an indica cultivar Wushansimiao, a major gene, tiller suppression 1 (ts1) was fine-mapped to a 108.5 kb genomic region between markers ID8378 and SSR6884 on the short arm of rice chromosome 2...
2017: PloS One
https://www.readbyqxmd.com/read/28107289/pre-symptomatic-diagnosis-of-celiac-disease-in-predisposed-children-the-role-of-gene-expression-profile
#5
Martina Galatola, Donatella Cielo, Camilla Panico, Pio Stellato, Basilio Malamisura, Lorenzo Carbone, Carmen Gianfrani, Riccardo Troncone, Luigi Greco, Renata Auricchio
OBJECTIVE: The prevalence of Celiac Disease (CD) has increased significantly in recent years, and risk prediction and early diagnosis has become imperative especially in at risk families. In a previous study, we identified individuals with CD based on the expression profile of a set of candidate genes in peripheral blood monocytes. Here we evaluated the expression of a panel of CD candidate genes in peripheral blood mononuclear cells (PBMCs) from at risk infants long time before any symptom or production of antibodies...
January 20, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28107015/non-uniform-excitonic-charge-distribution-enhances-exciton-phonon-coupling-in-znse-cdse-alloyed-quantum-dots
#6
Ke Gong, David F Kelley, Anne Myers Kelley
Zinc to cadmium cation exchange of ZnSe quantum dots has been used to produce a series of alloyed Zn1-xCdxSe quantum dots. As x increases and the lowest-energy exciton shifts to the red, the peak initially broadens and then sharpens as x approaches 1. Resonance Raman spectra obtained with excitation near the lowest excitonic absorption peak show a gradual shift of the longitudinal optical phonon peak from 251 cm(-1) in pure ZnSe to 210 cm(-1) in nearly pure CdSe with strong broadening at intermediate compositions...
January 20, 2017: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/28106925/clinical-study-evaluating-the-accuracy-of-injecting-the-distal-tarsal-joints-in-the-horse
#7
K A Seabaugh, K T Selberg, P O E Mueller, R B Eggleston, J F Peroni, K M Claunch, H J Markwell, G M Baxter
BACKGROUND: Osteoarthritis (OA) of the centrodistal (CD) and tarsometatarsal (TMT) joints is a common cause of lameness in horses. Intra-articular diagnostic anaesthesia and/or therapeutic injection are relied upon to help diagnose and treat many horses with OA of these joints. OBJECTIVES: The objective of this study was to determine the accuracy of arthrocentesis of the CD and TMT joints using a sample population of equine surgeons and surgery residents. STUDY DESIGN: Randomised experimental study...
January 20, 2017: Equine Veterinary Journal
https://www.readbyqxmd.com/read/28106739/transition-metal-complexes-coordinated-by-water-soluble-phosphane-ligands-how-cyclodextrins-can-alter-the-coordination-sphere
#8
Michel Ferreira, Hervé Bricout, Sébastien Tilloy, Eric Monflier
The behaviour of platinum(II) and palladium(0) complexes coordinated by various hydrosoluble monodentate phosphane ligands has been investigated by (31)P{¹H} NMR spectroscopy in the presence of randomly methylated β-cyclodextrin (RAME-β-CD). This molecular receptor can have no impact on the organometallic complexes, induce the formation of phosphane low-coordinated complexes or form coordination second sphere species. These three behaviours are under thermodynamic control and are governed not only by the affinity of RAME-β-CD for the phosphane but also by the phosphane stereoelectronic properties...
January 17, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28106279/a-rapid-electrochemical-monitoring-platform-for-sensitive-determination-of-thiamethoxam-based-on-%C3%AE-cyclodextrin-graphene-composite
#9
XingChen Zhai, Hua Zhang, Min Zhang, Xin Yang, Cheng Gu, GuoPeng Zhou, Haitian Zhao, Zhenyu Wang, Aijun Dong, Jing Wang
A rapid monitoring platform for sensitive voltammetric detection of thiamethoxam (TMX) residues was reported in the present study. The β-cyclodextrin-reduced graphene oxide composite (β-CD-rGO) was used as a reinforcing material in electrochemical determination of TMX. Compared with bare glassy carbon electrode (GCE), the reduction peak currents of TMX at rGO/GCE and β-CD-rGO/GCE were increased by 70 and 124 folds, respectively. The experimental conditions influencing voltammetric determination of TMX, such as the amount of β-CD-rGO, solution pH, temperature and time on accumulation, were optimized...
January 20, 2017: Environmental Toxicology and Chemistry
https://www.readbyqxmd.com/read/28106264/role-of-microbial-inoculation-and-industrial-by-product-phosphogypsum-on-growth-and-nutrients-uptake-of-maize-zea-mays-l-grown-in-calcareous-soil
#10
Abdul-Aziz R Al-Enazy, Saud S Al-Oud, Fahad N Al-Barakah, R A Adel, Usman
BACKGROUND: Alkaline soils with high calcium carbonate and low organic matter are deficient in plant nutrients availability. Use of organic and bio-fertilizers has been suggested to improve their properties. Therefore, a greenhouse experiment was conducted to evaluate the integrative role of phosphogypsum (PG; added at 0.0, 10, 30, and 50 g PG kg(-1) ), cow manure (CM; added at 50 g kg(-1) ) and mixed microbial inoculation (Incl; Azotobacter chroococcum, phosphate-solubilizing bacterium of Bacillus megaterium var...
January 20, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28106186/the-gold-iii-co-bond-a-missing-piece-in-the-gold-carbonyl-complex-landscape
#11
Carlo Alberto Gaggioli, Leonardo Belpassi, Francesco Tarantelli, Paola Belanzoni
We investigate the Au(iii)-CO bond in the [(C(∧)N(∧)C)Au(iii)CO](+) complex via charge-displacement (CD) analysis, revealing surprising peculiarities with respect to the Au(i)-CO bond. It shows a large Au(iii) ← CO σ donation and, unexpectedly, an even larger Au(iii) → CO π back-donation. The overall bonding picture, including a marked anisotropy in the Au(iii) → CO in-plane and out-of-plane π back-donation components, is consistent with a CO carbon atom highly susceptible to nucleophilic attack...
January 20, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28105809/two-3d-cd-ii-metal-organic-frameworks-linked-by-benzothiadiazole-dicarboxylates-fantastic-s-cd6-cage-benzothiadiazole-antidimmer-and-dual-emission
#12
Qing Cheng, Xiao Han, Yue Tong, Chao Huang, Jie Ding, Hongwei Hou
On the basis of the same benzothiadiazole (BTD) ligand 2,1,3-benzothiadiazole-4,7-dicarboxylic acid (H2L), two new isomers of three-dimensional (3D) BTD-derived Cd(II) metal-organic frameworks 1-2 {[S@Cd6L6]·xH2O}n were obtained by the different solvothermal reactions, which were structurally similar. Surprisingly, structural analyses reveal that in 1 or 2, one free sulfur atom was fixed in a Cd(II) cluster cage by strong intermolecular interaction to form the secondary building unit (SBU) S@Cd6. Each SBU S@Cd6 is connected by six L(2-) ligands and further extended into the 3D porous framework...
January 20, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28105778/psychosocial-screening-and-management-of-young-people-aged-18-25-years-with-diabetes
#13
Helen d'Emden, Brett McDermott, Neisha D'Silva, Tom Dover, Tatjana Ewais, Kristen Gibbons, Trisha O'Moore-Sullivan
BACKGROUND: Routine psychosocial screening and management of people with diabetes is recommended. AIMS: To profile demographic, medical and psychosocial characteristics of young people with diabetes, and to develop a screening tool and care pathway for routine use. METHODS: Indices of diabetes control and recorded diabetes complications were complimented by psychosocial screening tools assessing psychological, diabetes specific, and perceived stress (K10, PAID, PSS), well-being (WHO-5), disordered eating ((EDI-3RC), compensatory behaviour questionnaire, social support (MSPSS), resilience (CD-2) and financial concerns...
January 20, 2017: Internal Medicine Journal
https://www.readbyqxmd.com/read/28105734/calcium-calmodulin-dependent-protein-kinase-mediates-the-intracellular-signaling-pathways-of-cardiac-apoptosis-in-mice-with-impaired-glucose-tolerance
#14
Marilen Federico, Enrique L Portiansky, Leandro Sommese, Francisco J Alvarado, Paula G Blanco, Carolina N Zanuzzi, John Dedman, Marcia Kaetzel, Xander H T Wehrens, Alicia Mattiazzi, Julieta Palomeque
Background The impact of cardiac apoptosis in pre-diabetic stages of diabetic cardiomyopathy is unknown. We described that myocytes from fructose-rich diet (FRD) animals exhibit arrhythmias produced by exacerbated Ca(2+) /calmodulin-protein kinase (CaMKII) activity, ryanodine receptors (RyR2) phosphorylation and sarcoplasmic reticulum (SR) Ca(2+) leak. We tested the hypothesis that this mechanism also underlies cardiac apoptosis in pre-diabetes. Methods and Results We generated a pre-diabetic model in mice fed with FRD...
January 20, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/28105709/the-impact-of-co-existing-immune-mediated-on-phenotype-and-outcomes-in-inflammatory-bowel-diseases
#15
G Conway, G Velonias, E Andrews, J J Garber, V Yajnik, A N Ananthakrishnan
BACKGROUND: Inflammatory bowel diseases lead to progressive bowel damage and need for surgery. While the increase in prevalence of other immune-mediated diseases in IBD is well recognised, the impact of this on the natural history of IBD is unknown. AIM: To determine the impact of concomitant immune-mediate disease on phenotypes and outcomes in IBD. METHODS: Patients with IBD enrolled in a prospective registry were queried about the presence of other immune-mediated diseases, defined as those where immune dysregulation plays a role in pathogenesis...
January 20, 2017: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/28105620/-effect-of-a-clinical-pathway-in-patients-with-crohn-s-disease-complicated-with-intestinal-obstruction
#16
Zhen Guo, Lei Cao, Jianfeng Gong, Yi Li, Lili Gu, Weiming Zhu, Jieshou Li
OBJECTIVE: To evaluate the effect of a clinical pathway for Crohn disease (CD) complicated with intestinal obstruction. METHODS: CD patients complicated with intestinal obstruction in Inflammatory Bowel Disease(IBD) Center of Jinling Hospital were enrolled. One hundred and nineteen CD patients from March 2014 to September 2015 received treatment with the clinical pathway (CP), which was developed based on medical evidence and experience of the IBD center in February 2014, as CP group...
January 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28105594/screening-of-inorganic-and-organic-contaminants-in-floodwater-in-paddy-fields-of-hue-and-thanh-hoa-in-vietnam
#17
Ha Thu Trinh, Helle Marcussen, Hans Christian B Hansen, Giang Truong Le, Hanh Thi Duong, Nguyen Thuy Ta, Trung Quang Nguyen, Soren Hansen, Bjarne W Strobel
In the rainy season, rice growing areas in Vietnam often become flooded by up to 1.5 m water. The floodwater brings contaminants from cultivated areas, farms and villages to the rice fields resulting in widespread contamination. In 2012 and 2013, the inorganic and organic contaminants in floodwater was investigated in Thanh Hoa and Hue. Water samples were taken at 16 locations in canals, paddy fields and rivers before and during the flood. In total, 940 organic micro-pollutants in the water samples were determined simultaneously by GC-MS method with automatic identification and quantification system (AIQS), while ICP-MS was used for determination of ten trace elements in the samples...
January 20, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28105592/investigation-of-heavy-metal-pollution-in-eastern-aegean-sea-coastal-waters-by-using-cystoseira-barbata-patella-caerulea-and-liza-aurata-as-biological-indicators
#18
S Aydın-Önen, M Öztürk
In order to have an extensive contamination profile of heavy metal levels (Cd, Cu, Fe, Mn, Ni, Pb, and Zn), seawater, sediment, Patella caerulea, Cystoseira barbata, and Liza aurata were investigated by using inductively coupled plasma-atomic emission spectrometry (ICP-AES). Samples were collected from five coastal stations along the eastern Aegean Sea coast (Turkey) on a monthly basis from July 2002 through May 2003. According to the results of this study, heavy metal levels were arranged in the following sequence: Fe > Pb > Zn > Mn > Ni > Cu > Cd for water, Fe > Cu > Mn > Ni > Zn > Pb > Cd for sediment, Fe > Zn > Mn > Pb > Ni > Cd > Cu for C...
January 19, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28105230/dendritic-cell-activated-cytokine-induced-killer-cell-mediated-immunotherapy-is-safe-and-effective-for-cancer-patients-65-years-old
#19
Yanfeng Liu, Haibo Liu, Hausheng Liu, Pengcheng He, Jing Li, Xin Liu, Limei Chen, Mengchang Wang, Jiejing Xi, Huaiyu Wang, Haitao Zhang, Ying Zhu, Wei Zhu, Jing Ning, Caili Guo, Chunhong Sun, Mei Zhang
Individuals >65 years old account for a large proportion of cancer patients, and usually have poor prognoses due to relative weaker physiological function and lower drug tolerance. To characterize the efficacy and safety of dendritic cell (DC)-activated cytokine-induced killer cell (CIK)-mediated treatment, and develop an adoptive immunotherapy for cancer patients >65 years old, a retrospective study was performed in 58 cancer sufferers who received 1-4 cycles of DC-activated CIK (DC-CIK) treatment and evaluated the response (tumor remission rate) and toxicity (side effects to the treatment)...
December 2016: Oncology Letters
https://www.readbyqxmd.com/read/28105220/overexpression-of-thy1-and-itga6-is-associated-with-invasion-metastasis-and-poor-prognosis-in-human-gallbladder-carcinoma
#20
Dan-Hua Zhang, Zhu-Lin Yang, En-Xiang Zhou, Xiong-Ying Miao, Qiong Zou, Jing-He Li, Lu-Feng Liang, Gui-Xiang Zeng, Sen-Lin Chen
Gallbladder cancer (GBC) is a rare but highly aggressive cancer for which no well-accepted prognostic biomarkers have been identified. Thymus cell antigen 1 (Thy1), also known as cluster of differentiation (CD)90, and integrin α6 (ITGA6), also known as CD49f, are important molecules in cancer and putative markers of various stem cell types. However, their role in GBC remains to be elucidated. In the present study, Thy1 and ITGA6 expression status in clinical GBC samples, which comprised squamous cell/adenosquamous carcinoma (SC/ASC) and adenocarcinoma (AC) subtypes, was investigated...
December 2016: Oncology Letters
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