Yusuke Shigeta, Tarek Saleh, Giada Benedetti, Lorenzo Caciolli, Jinke Chang, Elisa Zambaiti, Lei Wu, Sahira Khalaf, Wulei Song, Alessandro Filippo Pellegata, Giovanni Giuseppe Giobbe, Paolo De Coppi
PURPOSE: Patients affected by microgastria, severe gastroesophageal reflux, or those who have undergone subtotal gastrectomy, have commonly described reporting dumping syndromes or other symptoms that seriously impair the quality of their life. Gastric tissue engineering may offer an alternative approach to treating these pathologies. Decellularization protocols have great potential to generate novel biomaterials for large gastric defect repair. There is an urgency to define more reliable protocols to foster clinical applications of tissue-engineered decellularized gastric grafts...
November 30, 2023: Pediatric Surgery International