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Gastroesophageal reflux in infants

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https://www.readbyqxmd.com/read/27916335/-gastroesophageal-reflux-and-sleep-position-of-infants-a-survey-conducted-in-france-by-493%C3%A2-pediatricians
#1
M Bellaïche, K Bargaoui, C Jung, P Maigret, P Clerson
BACKGROUND AND AIMS: The supine sleeping position with the head higher than the legs has no impact on regurgitations in infants. Inclined ventral decubitus decreases regurgitations but is associated with an increased risk of sudden infant death syndrome (SIDS). The LUNE study aimed to evaluate the impact of regurgitations on the choice of sleeping position by pediatricians and parents. METHODS: Cross-sectional case-control study (ratio 1:1) conducted in France in 2013...
December 1, 2016: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/27867686/widespread-use-of-gastric-acid-inhibitors-in-infants-are-they-needed-are-they-safe
#2
REVIEW
Mark Safe, Wei H Chan, Steven T Leach, Lee Sutton, Kei Lui, Usha Krishnan
Gastroesophageal reflux is a common phenomenon in infants, but the differentiation between gastroesophageal reflux and gastroesophageal reflux disease can be difficult. Symptoms are non-specific and there is increasing evidence that the majority of symptoms may not be acid-related. Despite this, gastric acid inhibitors such as proton pump inhibitors are widely and increasingly used, often without objective evidence or investigations to guide treatment. Several studies have shown that these medications are ineffective at treating symptoms associated with reflux in the absence of endoscopically proven oesophagitis...
November 6, 2016: World Journal of Gastrointestinal Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/27820755/the-impact-of-breast-milk-respiratory-insufficiency-and-gerd-on-enteral-feeding-in-infants-with-omphalocele
#3
Shelly Haug, Shawn St Peter, Sandhya Ramlogan, Donna Goff, Donna Thorpe, Andrew Hopper, Joanne Baerg
OBJECTIVES: The aim of this study was to document the process of achieving full enteral feeding in infants with omphalocele and to identify factors that affect feeding success. METHODS: After Institutional Review Board approval (5100169), 123 infants with omphalocele, born between 1993 and 2011 were reviewed. Mortalities were excluded. All survivors had complete follow-up. Variables suspected to impact enteral feeding in infants with non-giant versus giant omphalocele were compared...
November 5, 2016: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/27792252/questionnaire-based-survey-in-a-developing-country-showing-non-compliance-with-paediatric-gastro-oesophageal-reflux-practice-guidelines
#4
Hayat Manasfi, Rima Hanna-Wakim, Imad Akel, Nadine Yazbeck
AIM: This 2015 study investigated whether Lebanese paediatricians diagnosed and managed gastroesophageal reflux disease (GERD) in infants and children in accordance with the 2009 guidelines from the North American and European Societies for Paediatric Gastroenterology, Hepatology and Nutrition. METHODS: Paediatricians members of the Lebanese Order of Physicians with updated email addresses were invited to complete a web-based survey between September and November 2015, to assess their knowledge and management of GERD...
October 28, 2016: Acta Paediatrica
https://www.readbyqxmd.com/read/27771653/infantile-achalasia-cardia
#5
Rupa Banerjee, Alpana Prasad, Vivek Kumar, Nishant Wadhwa
BACKGROUND: Achalasia is extremely rare in infants. CASE CHARACTERISTICS: We report three infants of age 9, 7 and 12 months, who presented with recurrent non-bilious vomiting, repeated chest infection and severe failure to thrive. Diagnosis of achalasia cardia was confirmed on contrast-swallow study. Hellers cardiomyotomy with fundoplication led to complete symptomatic relief, and weight-gain on follow-up. MESSAGE: Achalasia cardia is often misdiagnosed as gastroesophageal reflux disease which leads to significant delay in diagnosis and increased morbidity...
September 8, 2016: Indian Pediatrics
https://www.readbyqxmd.com/read/27755341/prevalence-of-malnutrition-and-feeding-difficulties-in-children-with-esophageal-atresia
#6
Jessica Menzies, Jennifer Hughes, Steven Leach, Yvonne Belessis, Usha Krishnan
OBJECTIVES: Growth and feeding problems have been described in children with Esophageal Atresia (EA). Ongoing gastrointestinal and respiratory complications such as Gastroesophageal Reflux Disease (GERD), esophageal dysmotility, strictures and respiratory infections may contribute. The aim of the study was to document the prevalence of malnutrition and feeding difficulties and examine predictive factors which may influence feeding and growth in children attending a multidisciplinary EA clinic in Sydney Australia...
October 13, 2016: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/27695493/congenital-duodenal-obstruction-with-delayed-presentation-seven-years-of-experience
#7
Seyed Abdollah Mousavi, Hasan Karami, Hossein Saneian
INTRODUCTION: The duodenum is the most common site for congenital intestinal obstruction. The duodenal web with a central hole can present without any overt signs of obstruction at a later age. MATERIAL AND METHODS: Over a 7-year period, children with congenital intestinal obstruction were identified in this study. The complications and operative findings of patients with duodenal web with conditions such as wind sock deformity and delayed diagnosis were evaluated in this study...
October 1, 2016: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/27692861/effect-of-severity-of-esophageal-acidification-on-sleep-vs-wake-periods-in-infants-presenting-with-brief-resolved-unexplained-events
#8
Janani Sankaran, Aslam H Qureshi, Frederick Woodley, Mark Splaingard, Sudarshan R Jadcherla
OBJECTIVES: To describe the pattern of gastroesophageal reflux (GER) events in wake and sleep states with increasing acid reflux index (ARI) in neonates and to test the hypothesis that GER-related symptoms are frequent in ARI >7% in wake state. STUDY DESIGN: Infants underwent 24-hour pH-impedance studies with 6-hour concurrent video-polysomnography studies. Data were stratified based on the 24-hour ARI (% duration that esophageal pH is <4) into ARI < 3% (normal), ARI 3 ≥ to ≤7% (intermediate), and ARI >7% (abnormal)...
September 27, 2016: Journal of Pediatrics
https://www.readbyqxmd.com/read/27682990/reflux-monitoring-in-children
#9
REVIEW
M M J Singendonk, M A Benninga, M P van Wijk
Recently, multichannel intraluminal impedance (MII) monitoring was added to the repertoire of tests to evaluate the (patho)physiology of gastroesophageal reflux (GER) in children. Its advantage above the sole monitoring of the esophageal pH lies in the ability of the detection of both acid and nonacid GER and to discern between liquid and gas GER. Currently, combined 24 h pH-MII monitoring is recommended for evaluation of gastro-esophageal reflux disease (GERD) and its relation to symptoms in infants and children, despite the lack of reference values in these age groups...
October 2016: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/27642394/pediatric-recurrent-respiratory-tract-infections-when-and-how-to-explore-the-immune-system-about-53-cases
#10
Mohammed El-Azami-El-Idrissi, Mounia Lakhdar-Idrissi, Sanae Chaouki, Samir Atmani, Abdelhak Bouharrou, Moustapha Hida
Recurrent respiratory tract infections are one of the most frequent reasons for pediatric visits and hospitalization. Causes of this pathology are multiple ranging from congenital to acquired and local to general. Immune deficiencies are considered as underlying conditions predisposing to this pathology. Our work is about to determine when and how to explore the immune system when facing recurrent respiratory infections. This was based on the records of 53 children hospitalized at the pediatrics unit of Hassan II University Hospital, Fez Morocco...
2016: Pan African Medical Journal
https://www.readbyqxmd.com/read/27641715/breastfeeding-improvement-following-tongue-tie-and-lip-tie-release-a-prospective-cohort-study
#11
Bobak A Ghaheri, Melissa Cole, Sarah C Fausel, Maria Chuop, Jess C Mace
OBJECTIVES/HYPOTHESIS: Numerous symptoms may arise that prevent mother-infant dyads from maintaining desired breastfeeding intervals. Investigations into treatments that positively influence breastfeeding outcomes allow for improved patient counseling for treatment decisions to optimize breastfeeding quality. This investigation aimed to determine the impact of surgical tongue-tie/lip-tie release on breastfeeding impairment. STUDY DESIGN: Prospective, cohort study from June 2014 to April 2015 in a private practice setting...
September 19, 2016: Laryngoscope
https://www.readbyqxmd.com/read/27637372/non-ige-mediated-gastrointestinal-food-allergies-in-children
#12
Jean-Christoph Caubet, Hania Szajewska, Raanan Shamir, Anna Nowak-Węgrzyn
Non-IgE-mediated gastrointestinal food allergic disorders (non-IgE-GI-FA) including food protein-induced enterocolitis syndrome (FPIES), food protein-induced enteropathy (FPE) and food protein-induced allergic proctocolitis (FPIAP) are relatively uncommon in infants and young children, but are likely under-diagnosed. Non-IgE-GI-FA have a favorable prognosis, with majority resolving by age 3-5 years. Diagnosis relies on the recognition of symptoms pattern in FPIAP and FPIES and biopsy in FPE. Further studies are needed for a better understanding of the pathomechanism, which will lead eventually to the development of diagnostic tests and treatments...
September 17, 2016: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/27607100/swallowing-dysfunction-and-quality-of-life-in-adults-with-surgically-corrected-esophageal-atresia-tracheoesophageal-fistula-as-infants-forty-years-of-follow-up
#13
Waleed Gibreel, Benjamin Zendejas, Ryan M Antiel, Geoffrey Fasen, Christopher R Moir, Abdalla E Zarroug
OBJECTIVES: The aim of the study was to evaluate and study the full spectrum of swallowing dysfunction and long-term disease-specific outcomes in adults with surgically corrected esophageal atresia/tracheaesophageal fistula (EA/TEF). BACKGROUND: Long-term outcomes for adults who underwent EA/TEF repair because infants are lacking. METHODS: We developed a disease-specific swallowing dysfunction questionnaire (SDQ) to assess swallowing dysfunction and quality of life (QOL) of adult patients with surgically corrected EA/TEF...
September 6, 2016: Annals of Surgery
https://www.readbyqxmd.com/read/27588933/dolichocephaly-in-preterm-infants-prevalence-risk-factors-and-early-motor-outcomes
#14
Dana B McCarty, Jennifer R Peat, William F Malcolm, P Brian Smith, Kimberley Fisher, Ricki F Goldstein
Objective The purpose of this study was to determine when dolichocephaly develops in preterm infants, to establish factors that contribute to its development, and to determine its association with adverse motor outcomes. Study Design This study was a retrospective review of data collected from preterm infants born at < 32 weeks' gestation. The cranial index was measured by a physical therapist (PT) at three time points during hospitalization. Demographic data, neonatal morbidities, and motor outcomes at outpatient follow-up were collected...
September 2, 2016: American Journal of Perinatology
https://www.readbyqxmd.com/read/27574881/combined-multichannel-intraluminal-impedance-and-ph-measurement-in-detecting-gastroesophageal-reflux-disease-in-children
#15
Mark Safe, Jemma Cho, Usha Krishnan
OBJECTIVE: The aim of the study was to evaluate and compare multichannel intraluminal impedance-pH (MII-pH) monitoring with standard investigations including pH testing for detecting gastroesophageal reflux disease (GERD) in children. METHODS: A retrospective review of all MII-pH studies performed between July 2007 and March 2013 at Sydney Children's Hospital. Results from MII-pH testing, esophagogastroduodenoscopy (EGD), barium meal and pepsin assay, symptoms, underlying comorbidities, age, and medication usage were evaluated...
November 2016: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/27561215/mosapride-for-gastroesophageal-reflux-disease-in-neurologically-impaired-patients
#16
Makoto Komura, Yutaka Kanamori, Yujiro Tanaka, Tetsuro Kodaka, Masahiko Sugiyama, Kan Terawaki, Kan Suzuki, Tadashi Iwanaka
BACKGROUND: The prokinetic agent cisapride is effective for the treatment of gastroesophageal reflux disease (GERD) in infants and children, but is no longer used for this purpose because of safety concerns. Therefore, other pharmacological agents need to be investigated for efficacy in GERD treatment. In this study, we examined the effectiveness and safety of mosapride for the treatment of neurologically impaired children and adolescents with GERD. METHODS: Mosapride (0...
August 26, 2016: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/27521711/gastroesophageal-reflux-disease-in-children
#17
Douglas C Barnhart
Despite the frequency with which antireflux procedures are performed, decisions about gastroesophageal reflux disease treatment remain challenging. Several factors contribute to the difficulties in managing gastroesophageal reflux. First, the distinction between physiologic and pathologic gastroesophageal reflux (gastroesophageal reflux disease-GERD) is not always clear. Second, measures of the extent of gastroesophageal reflux often poorly correlate to symptoms or other complications attributed to reflux in infants and children...
August 2016: Seminars in Pediatric Surgery
https://www.readbyqxmd.com/read/27516725/clinical-utility-of-bronchoalveolar-lavage-pepsin-in-diagnosis-of-gastroesophageal-reflux-among-wheezy-infants
#18
Ahmed Fathi Abdallah, Tarek El-Desoky, Khalid Fathi, Wagdy Fawzi Elkashef, Ahmed Zaki
Background. There is no gold standard test for diagnosis of gastroesophageal reflux disease (GERD) associated infantile wheezing. Objectives. To evaluate the value of bronchoalveolar lavage (BAL) pepsin assay in diagnosis of GERD in wheezy infants. Methods. Fifty-two wheezy infants were evaluated for GERD using esophageal combined impedance-pH (MII-pH) monitoring, esophagogastroduodenoscopy with esophageal biopsies, and BAL pepsin. Tracheobronchial aspirates from 10 healthy infants planned for surgery without history of respiratory problems were examined for pepsin...
2016: Canadian Respiratory Journal: Journal of the Canadian Thoracic Society
https://www.readbyqxmd.com/read/27461430/evaluation-of-the-intraoperative-risk-factors-for-esophageal-anastomotic-complications-after-primary-repair-of-esophageal-atresia-with-tracheoesophageal-fistula
#19
Yuichi Okata, Kosaku Maeda, Yuko Bitoh, Yasuhiko Mishima, Akihiko Tamaki, Keiichi Morita, Kosuke Endo, Chieko Hisamatsu, Hiroaki Fukuzawa, Akiko Yokoi
PURPOSE: The aim of this study is to identify the risk factors for esophageal anastomotic stricture (EAS) and/or anastomotic leakage (EAL) after primary repair of esophageal atresia with tracheoesophageal fistula (EA/TEF) in infants. METHODS: A retrospective chart review of 52 patients with congenital EA/TEF between January 2000 and December 2015 was conducted. Univariate and multivariate analyses were performed to identify the risk factors for anastomotic complications...
September 2016: Pediatric Surgery International
https://www.readbyqxmd.com/read/27412554/-research-advances-in-the-relationship-between-cow-s-milk-allergy-and-gastroesoph-ageal-reflux-in-infants
#20
REVIEW
Ming-Fang Sun, Mi-Zu Jiang
Gastroesophageal reflux (GER) and cow's milk allergy (CMA) are common disorders in infants. In recent years, more and more research has investigated the relationship between these two diseases. Some studies reported that about half of the cases of GER in infants younger than 1 year may be an association with CMA. Therefore, overall understanding the role of CMA on the pathogenesis of GER has a great importance on improving clinical level of diagnosis and therapy. This review article tried to elaborate advances in research on the relationship between CMA and GER in infants, including epidemiology, pathogenesis, clinical manifestations, diagnosis and treatment...
July 2016: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
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