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Gastroesophageal reflux in infants

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https://www.readbyqxmd.com/read/29444224/a-systematic-review-with-meta-analysis-of-the-prevalence-of-gastroesophageal-reflux-in-congenital-diaphragmatic-hernia-pediatric-survivors
#1
J V Arcos-Machancoses, C Ruiz Hernández, J Martin de Carpi, S Pinillos Pisón
Congenital diaphragmatic hernia survivors are a well-known group at risk for developing gastroesophageal reflux disease that may be particularly long-term severe. The aim of this study is to provide a systematic review of the prevalence of gastroesophageal reflux in infant and children survivors treated for congenital diaphragmatic hernia.Electronic and manual searches were performed with keywords related to congenital diaphragmatic hernia, gastroesophageal reflux disease, and epidemiology terms. Summary estimates of the prevalence were calculated...
February 9, 2018: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/29438655/short-term-neurodevelopmental-outcome-in-children-born-with-high-risk-congenital-lung-lesions
#2
Enrico Danzer, Casey Hoffman, Jo Ann D'Agostino, Matthew M Boelig, Marsha Gerdes, Judy C Bernbaum, Hannah Rosenthal, Lindsay N Waqar, Natalie E Rintoul, Lisa M Herkert, Michael J Kallan, William H Peranteau, Alan W Flake, N Scott Adzick, Holly L Hedrick
BACKGROUND: To evaluate neurodevelopmental outcome in high-risk congenital lung lesions (CLLs) survivors who underwent prenatal intervention or postnatal surgery within the first month of life. METHODS: Forty-five high-risk CLLs survivors underwent assessment using the Bayley Scales of Infant Development, 3rd Edition between 07/2004 and 12/2016. Scores were grouped as average, at-risk, and delayed based on standard deviation intervals. Correlations between outcome and risk factors were analyzed by Fisher's exact test or two-sided t-test as appropriate, with significant p-values <0...
February 10, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29436357/acid-suppression-for-gastroesophageal-reflux-disease-in-infants
#3
Sara E Rostas, Christopher McPherson
Gastroesophageal reflux is a normal physiologic occurrence that is common throughout infancy and usually resolves on its own. Infrequently, reflux causes complications and turns into gastroesophageal reflux disease (GERD), which may warrant intervention. Available interventions vary in invasiveness and supporting data may be lacking for efficacy and safety. Nonpharmacologic interventions are first-line therapy for GERD in infants, whereas pharmacologic and surgical approaches are controversial. Efficacy data are limited for pharmacologic strategies for infantile GERD and safety data have demonstrated serious risks, especially in younger infants...
January 1, 2018: Neonatal Network: NN
https://www.readbyqxmd.com/read/29436213/gastric-reflux-comparison-between-the-gastroenterologist-and-the-otorhinolaryngologist%C3%A2-s-approach-pragmatic-conclusive-remarks
#4
G Ciprandi, M Gelardi
Gastroesophageal reflux (GER) is a normal physiological process that usually happens after eating in healthy infants, children, young people and adults. In contrast, gastroesophageal reflux disease (GERD) occurs when the effect of GER leads to symptoms severe enough to merit medical treatment. In clinical practice, it is difficult to differentiate between GER and GERD, and health professionals and families use the terms interchangeably alike. There is no simple, reliable and accurate diagnostic test to confirm whether the condition is GER or GERD, and this in turn affects research and clinical decisions (1-6)...
January 2018: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/29431474/maternal-carbamazepine-therapy-and-unusual-adverse-effects-in-a-breastfed-infant
#5
Roberto Antonucci, Laura Cuzzolin, Alessandra Manconi, Claudio Cherchi, Anna Maria Oggiano, Cristian Locci
BACKGROUND: Usually, no adverse effects are observed in breastfed infants whose mothers are treated with the anti-epileptic carbamazepine. In this article, we described unusual short-term adverse effects observed in a young infant after exposure to carbamazepine during pregnancy and lactation. CASE REPORT: A 40-day-old female infant, born at term, was admitted to the Pediatric Clinic at University of Sassari, Italy, for recurrent regurgitations and vomiting. She was breastfed since birth and her mother was under chronic carbamazepine therapy...
February 12, 2018: Breastfeeding Medicine: the Official Journal of the Academy of Breastfeeding Medicine
https://www.readbyqxmd.com/read/29413212/gastroesophageal-reflux-regurgitation-in-the-infant-population
#6
REVIEW
Teresa D Ferguson
Gastroesophageal reflux (GER) is common in infancy and mainly treated through nonpharmacological interventions. Knowing the early warning signs of GER is important for nursing assessment. Untreated GER can become acute when an infant fails to gain weight and has recurrent, forceful vomiting. Further investigation of gastroesophageal reflux disease (GERD) is indicated when failure to gain weight, irritability, swallowing difficulties, regurgitation, and respiratory complications occur and should trigger referral to pediatric specialists...
March 2018: Critical Care Nursing Clinics of North America
https://www.readbyqxmd.com/read/29394212/survey-on-the-adherence-to-the-2009-naspghan-espghan-gastroesophageal-reflux-guidelines-by-brazilian-paediatricians
#7
Sarah Cristina Fontes Vieira, Flavia Matos Gurgel, Maria Zuleide Leão, Tiê Emídio Costa-Silva, Ikaro Daniel de Carvalho Barreto, Paulo Ricardo Saquete Martins-Filho, Mário C Vieira, Ricardo Queiroz Gurgel
OBJECTIVE: To evaluate the management of gastroesophageal reflux in children among Brazilian pediatricians and adherence to the 2009 North American Society of Pediatric Gastroenterology, Hepatology, and Nutrition (NASPGHAN), and European Society of Gastroenterology, Hepatology, and Nutrition (ESPGHAN) Guideline in Brazil. METHODS: An observational cross-sectional study was conducted, applying a standard questionnaire with 12 questions about gastroesophageal reflux (GER) and gastroesophageal reflux disease (GERD) management in infants, children, and adolescents to the pediatricians during the 37th Brazilian Pediatrics Congress in October, 2015...
February 1, 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29390957/streptococcus-agalactiae-meningoencephalitis-associated-with-gastroesophageal-reflux-disease-and-chronic-proton-pump-inhibitors-use-in-a-9%C3%A2-month-old-infant-a-case-report
#8
Victoria Bîrluţiu, Codruța Mihaela Luca, Rareș-Mircea Bîrluțiu
BACKGROUND: Streptococcus agalactiae (Group B Streptococcus) is recognized as the etiologic agent of newborn and infant meningitis, aged up to 90 days, starting from the colonization of the maternal genital or gastrointestinal tract, but it is rarely responsible for meningitis in old infants. CASE PRESENTATION: We present the case of a 9 month-old infant diagnosed with S. agalactiae meningoencephalitis associated with chronic gastroesophageal reflux disease treated with a proton pump inhibitor (PPI)...
February 1, 2018: BMC Pediatrics
https://www.readbyqxmd.com/read/29373438/pediatric-gastroesophageal-reflux-clinical-practice-guidelines-joint-recommendations-of-the-north-american-society-for-pediatric-gastroenterology-hepatology-and-nutrition-naspghan-and-the-european-society-for-pediatric-gastroenterology-hepatology-and-nutrition
#9
Rachel Rosen, Yvan Vandenplas, Maartje Singendonk, Michael Cabana, Carlo Di Lorenzo, Frederic Gottrand, Sandeep Gupta, Miranda Langendam, Annamaria Staiano, Nikhil Thapar, Neelesh Tipnis, Merit Tabbers
This document serves as an update of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition (NASPGHAN) and the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN) 2009 clinical guidelines for the diagnosis and management of gastroesophageal reflux disease (GERD) in infants and children and is intended to be applied in daily practice and as a basis for clinical trials. Eight clinical questions addressing diagnostic, therapeutic and prognostic topics were formulated...
January 25, 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29324645/esophageal-web-in-a-down-syndrome-infant-a-rare-case-report
#10
Nirmala Thomas, Roy J Mukkada, Muhammed Jasim Abdul Jalal, Nisha Narayanankutty
We describe the rare case of an infant with trisomy 21 who presented with recurrent vomiting and aspiration pneumonia and a failure to thrive. Infants with Down's syndrome have been known to have various problems in the gastrointestinal tract. In the esophagus, what have been described are dysmotility, gastroesophageal reflux and strictures. This infant on evaluation was found to have an esophageal web and simple endoscopic dilatation relieved the infant of her symptoms. No similar case has been reported in literature...
January 11, 2018: Children
https://www.readbyqxmd.com/read/29276590/correlation-of-gastroesophageal-reflux-disease-assessment-symptom-questionnaire-to-impedance-ph-measurements-in-children
#11
Sittichoke Prachuapthunyachart, Chaowapong Jarasvaraparn, David A Gremse
Background: Esophageal multichannel intraluminal impedance-pH monitoring has become one of the preferred tests to correlate observed reflux-like behaviors with esophageal reflux events. The Gastroesophageal reflux disease Assessment Symptom Questionnaire is a validated tool used to distinguish infants with gastroesophageal reflux disease from healthy children. The aim of this study was to determine whether the Gastroesophageal reflux disease Assessment Symptom Questionnaire composite symptom scores and individual symptom scores correlate with outcomes in esophageal multichannel intraluminal impedance-pH monitoring...
2017: SAGE Open Medicine
https://www.readbyqxmd.com/read/29205957/comparison-of-two-tools-to-assess-dyad-feeding-interaction-in-infants-with-gastroesophageal-reflux-disease
#12
Meredith Jameson, Karen Fehringer, Madalynn Neu
PURPOSE: The aim of this study was to compare the Mother-Infant/Toddler Feeding Scale (MITFS) and the Nursing Child Assessment Feeding Scale (NCAFS). Specific questions were as follows: (1) Are there differences between the results of the MITFS and the NCAFS tools in terms of rating infant feeding interactions? And (2) does one tool provide a more detailed, nuanced overview of the quality of feeding interactions than the other? DESIGN AND METHODS: This comparative descriptive study is a secondary analysis of a study evaluating a massage intervention for infants with symptoms of gastroesophageal reflux disease (GERD)...
December 4, 2017: Journal for Specialists in Pediatric Nursing: JSPN
https://www.readbyqxmd.com/read/29190845/nasogastric-feeding-tubes-may-not-contribute-to-gastroesophageal-reflux-in-preterm-infants
#13
Swati V Murthy, Apryle Funderburk, Sheeja Abraham, Michele Epstein, Joan DiPalma, Zubair H Aghai
No abstract text is available yet for this article.
November 30, 2017: American Journal of Perinatology
https://www.readbyqxmd.com/read/29128854/pharmacological-management-of-gastroesophageal-reflux-disease-in-infants-current-opinions
#14
REVIEW
Mohamed A El-Mahdy, Fatma A Mansoor, Sudarshan R Jadcherla
Gastroesophageal reflux disease (GERD) constitutes a troublesome symptom complex resulting from retrograde passage of gastric contents into the esophagus or extra-esophageal regions. Premature-born, high-risk infants and those with neuro-aero-digestive pathologies are at increased risk. Critical review over the last 3 years was conducted, and current opinions on pharmacological targets include agents aimed at prevention of transient lower esophageal sphincter relaxation, modification of the physico-chemical composition of gastric contents, modification of gut motility, or altering sensory thresholds to ameliorate the troublesome symptoms...
December 2017: Current Opinion in Pharmacology
https://www.readbyqxmd.com/read/29127961/fundoplication
#15
REVIEW
Bethany J Slater, Steven S Rothenberg
Gastroesophageal reflux disease (GERD) is a common condition in infants. Symptoms from pathologic GERD include regurgitation, irritability when feeding, failure to thrive, and respiratory problems. Treatment typically starts with dietary modifications and postural changes. Antireflux medications may then be added. Indications for operative management in neonates and infants include poor weight gain, failure to thrive, acute life-threatening events, and continued respiratory symptoms. Laparoscopic Nissen fundoplication has become the standard of care for surgical treatment of children with GERD...
December 2017: Clinics in Perinatology
https://www.readbyqxmd.com/read/29095882/the-comparative-analyses-of-different-diagnostic-approaches-in-detection-of-gastroesophageal-reflux-disease-in-children
#16
Nina Ristic, Ivan Milovanovic, Milica Radusinovic, Marija Stevic, Milos Ristic, Maja Ristic, Darija Kisic Tepavcevic, Tamara Alempijevic
OBJECTIVES: The aim of this study was to compare the different diagnostic approaches in detection of gastroesophageal reflux disease in children presented with symptoms suggesting gastroesophageal reflux disease. METHODS: The study design was cross sectional. The study retrospectively included all children who underwent combined multiple intraluminal impedance and pH (pH-MII) monitoring due to gastrointestinal and/or extraesophageal symptoms suggesting gastroesophageal reflux disease at University Children's Hospital in Belgrade, from July 2012 to July 2016...
2017: PloS One
https://www.readbyqxmd.com/read/29075620/the-influence-of-proton-pump-inhibitors-on-the-fecal-microbiome-of-infants-with-gastroesophageal-reflux-a-prospective-longitudinal-interventional-study
#17
Christoph Castellani, Georg Singer, Karl Kashofer, Andrea Huber-Zeyringer, Christina Flucher, Margarita Kaiser, Holger Till
Proton pump inhibitors (PPIs) are the standard therapy for gastroesophageal reflux disease. In adults, PPI treatment is associated with Clostridium difficile infections (CDI). In contrast to adults the microbiome of infants develops from sterility at birth toward an adult-like profile in the first years of life. The effect of PPIs on this developing microbiome has never been studied. The aim of the present study was to determine the effect of oral PPIs on the fecal microbiome in infants with gastroesophageal reflux disease (GERD)...
2017: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/28954042/antisecretory-treatment-for-pediatric-gastroesophageal-reflux-disease-a-systematic-review
#18
Ângelo Zambam de Mattos, Gabriela Meirelles Marchese, Bárbara Brum Fonseca, Carlos Kupski, Marta Brenner Machado
BACKGROUND: Proton pump inhibitors and histamine H2 receptor antagonists are two of the most commonly prescribed drug classes for pediatric gastroesophageal reflux disease, but their efficacy is controversial. Many patients are treated with these drugs for atypical manifestations attributed to gastroesophageal reflux, even that causal relation is not proven. OBJECTIVE: To evaluate the use of proton pump inhibitors and histamine H2 receptor antagonists in pediatric gastroesophageal reflux disease through a systematic review...
September 21, 2017: Arquivos de Gastroenterologia
https://www.readbyqxmd.com/read/28892950/riley-day-syndrome-in-a-hispanic-infant-of-non-jewish-ashkenazi-descent
#19
Abel Ramírez-Estudillo, Gerardo González-Saldivar, Itzel Espinosa-Soto, Jesús González-Cortez, Alejandro Salcido-Montenegro
Riley-Day syndrome is an autosomal recessive sensory and autonomic neuropathy. Patients present a lack of fungiform papilla, alacrima and usually feeding difficulties. It is present almost exclusively in Ashkenazi Jewish individuals and has a poor prognosis. We describe an unusual case of Riley-Day syndrome with pseudostrabismus in a non-Ashkenazi Jewish patient. A one-year-old female infant was referred for evaluation of strabismus, absence of fungiform papillae, feeding difficulty, gastroesophageal reflux and episodes of self-mutilation...
July 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28828751/maturation-modulates-pharyngeal-stimulus-provoked-pharyngeal-and-respiratory-rhythms-in-human-infants
#20
Kathryn A Hasenstab, Swetha Sitaram, Ivan M Lang, Reza Shaker, Sudarshan R Jadcherla
Pharyngeal-provocation induced aerodigestive symptoms in infants remain an enigma. Sources of pharyngeal provocation can be anterograde as with feeding, and retrograde as in gastroesophageal reflux. We determined maturational and dose-response effects of targeted pharyngeal-stimulus on frequency, stability, and magnitude of pharyngeal and respiratory waveforms during multiple pharyngeal swallowing responses in preterm-born infants when they were of full-term postmenstrual age (PMA). Eighteen infants (11 male) were studied longitudinally at 39...
August 21, 2017: Dysphagia
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