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https://www.readbyqxmd.com/read/27667777/networks-underlying-trait-impulsivity-evidence-from-voxel-based-lesion-symptom-mapping
#1
Valerie McDonald, Katherina K Hauner, Aileen Chau, Frank Krueger, Jordan Grafman
Impulsivity is considered a multidimensional construct that encompasses a range of behaviors, including poor impulse control, premature decision-making, and the inability to delay gratification. In order to determine the extent to which impulsivity and its components share a common network, a voxel-based lesion-symptom mapping (VLSM) analysis was performed in a large sample of patients (N = 131) with focal, penetrating traumatic brain injuries (pTBI). Impulsivity was assessed using the Barratt Impulsiveness Scale (BIS-11), a standard self-report measure that allows for unique estimates of global impulsivity and its factor analysis-derived components (e...
September 26, 2016: Human Brain Mapping
https://www.readbyqxmd.com/read/27397858/derivatization-strategy-for-the-comprehensive-characterization-of-endogenous-fatty-aldehydes-using-hplc-multiple-reaction-monitoring
#2
Cai Tie, Ting Hu, Zhi-Xin Jia, Jin-Lan Zhang
Fatty aldehydes are crucial substances that mediate a wide range of vital physiological functions, particularly lipid peroxidation. Fatty aldehydes such as acrolein and 4-hydroxynonenal (4-HNE) are considered potential biomarkers of myocardial ischemia and dementia, but analytical techniques for fatty aldehydes are lacking. In the present study, a comprehensive characterization strategy with high sensitivity and facility for fatty aldehydes based on derivatization and high-performance liquid chromatography-multiple reaction monitoring (HPLC-MRM) was developed...
August 2, 2016: Analytical Chemistry
https://www.readbyqxmd.com/read/27329520/larger-corpus-callosum-and-reduced-orbitofrontal-cortex-homotopic-connectivity-in-codeine-cough-syrup-dependent-male-adolescents-and-young-adults
#3
Ying-Wei Qiu, Xiao-Fei Lv, Gui-Hua Jiang, Huan-Huan Su, Xiao-Fen Ma, Jun-Zhang Tian, Fu-Zhen Zhuo
OBJECTIVES: To characterize interhemispheric functional and anatomical connectivity and their relationships with impulsive behaviour in codeine-containing cough syrup (CCS)-dependent male adolescents and young adults. METHODS: We compared volumes of corpus callosum (CC) and its five subregion and voxel-mirrored homotopic functional connectivity (VMHC) in 33 CCS-dependent male adolescents and young adults and 38 healthy controls, group-matched for age, education and smoking status...
June 21, 2016: European Radiology
https://www.readbyqxmd.com/read/27199831/altered-gray-matter-volume-and-white-matter-integrity-in-college-students-with-mobile-phone-dependence
#4
Yongming Wang, Zhiling Zou, Hongwen Song, Xiaodan Xu, Huijun Wang, Federico d'Oleire Uquillas, Xiting Huang
Mobile phone dependence (MPD) is a behavioral addiction that has become an increasing public mental health issue. While previous research has explored some of the factors that may predict MPD, the underlying neural mechanisms of MPD have not been investigated yet. The current study aimed to explore the microstructural variations associated with MPD as measured with functional Magnetic Resonance Imaging (fMRI). Gray matter volume (GMV) and white matter (WM) integrity [four indices: fractional anisotropy (FA); mean diffusivity (MD); axial diffusivity (AD); and radial diffusivity (RD)] were calculated via voxel-based morphometry (VBM) and tract-based spatial statistics (TBSS) analysis, respectively...
2016: Frontiers in Psychology
https://www.readbyqxmd.com/read/26858620/altered-structural-correlates-of-impulsivity-in-adolescents-with-internet-gaming-disorder
#5
Xin Du, Xin Qi, Yongxin Yang, Guijin Du, Peihong Gao, Yang Zhang, Wen Qin, Xiaodong Li, Quan Zhang
Recent studies suggested that internet gaming disorder (IGD) was associated with impulsivity and structural abnormalities in brain gray matter (GM). However, no morphometric study has examined the association between GM and impulsivity in IGD individuals. In this study, 25 adolescents with IGD and 27 healthy controls (HCs) were recruited, and the relationship between Barratt impulsiveness scale-11 (BIS) score and gray matter volume (GMV) was investigated with the voxel-based morphometric (VBM) correlation analysis...
2016: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/26711526/impulsivity-across-the-psychosis-spectrum-correlates-of-cortical-volume-suicidal-history-and-social-and-global-function
#6
Pranav Nanda, Neeraj Tandon, Ian T Mathew, Jaya L Padmanabhan, Brett A Clementz, Godfrey D Pearlson, John A Sweeney, Carol A Tamminga, Matcheri S Keshavan
Patients with psychotic disorders appear to exhibit greater impulsivity-related behaviors relative to healthy controls. However, the neural underpinning of this impulsivity remains uncertain. Furthermore, it remains unclear how impulsivity might differ or be conserved between psychotic disorder diagnoses in mechanism and manifestation. In this study, self-reported impulsivity, measured by Barratt Impulsiveness Scale (BIS), was compared between 305 controls (HC), 139 patients with schizophrenia (SZ), 100 with schizoaffective disorder (SZA), and 125 with psychotic bipolar disorder (PBP)...
January 2016: Schizophrenia Research
https://www.readbyqxmd.com/read/26615579/color-density-spectral-array-of-bilateral-bispectral-index-system-electroencephalographic-correlate-in-comatose-patients-with-nonconvulsive-status-epilepticus
#7
Miguel A Hernández-Hernández, José L Fernández-Torre
PURPOSE: to describe the characteristics of the color density spectral array (CDSA) of bilateral bispectral index (b-BIS) monitoring system in patients with comatose nonconvulsive status epilepticus (NCSE). We hypothesized that CDSA could be helpful for monitoring NCSE in critically subjects if continuous EEG (cEEG) is not available. METHODS: we retrospectively analyzed comatose patients admitted to our neurological intensive care unit (NICU) from 2011 to 2014 with a diagnosis of definitive NCSE that underwent b-BIS monitoring for at least 24h to guide anesthetic sedation...
January 2016: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/26550355/application-of-ultrasound-guided-subcostal-transversus-abdominis-plane-block-in-gastric-cancer-patients-undergoing-open-gastrectomy
#8
Kai Li, Longyun Li, Ming Gao, Zhihua Zhu, Peng Chen, Li Yang, Guoqing Zhao
BACKGROUND: To observe intraoperative and postoperative analgesic effect of ultrasound-guided subcostal transversus abdominis plane (TAP) block in gastric cancer patients undergoing open gastrectomy. MATERIAL AND METHODS: Forty patients with gastric cancer underwent open gastrectomy were randomly assigned into groups R and S. All patients received ultrasound-guided subcostal bilateral TAP under general anesthesia, and then were injected with 40 ml of 0.375% ropivacaine (group R) or equivalent amount of normal saline (group S)...
2015: International Journal of Clinical and Experimental Medicine
https://www.readbyqxmd.com/read/26076217/patient-satisfaction-and-nipple-areola-sensitivity-after-bilateral-prophylactic-mastectomy-and-immediate-implant-breast-reconstruction-in-a-high-breast-cancer-risk-population-nipple-sparing-mastectomy-versus-skin-sparing-mastectomy
#9
Victorien M T van Verschuer, Marc A M Mureau, Jessica P Gopie, Elvira L Vos, Cornelis Verhoef, Marian B E Menke-Pluijmers, Linetta B Koppert
BACKGROUND: Prophylactic skin-sparing mastectomy (SSM) and nipple-sparing mastectomy (NSM) both are associated with major risk reduction in women with high breast cancer risk. Skin-sparing mastectomy followed by nipple-areola complex (NAC) reconstruction is standard of care, but NSM is increasingly being performed. Preservation of the NAC in NSM may increase patient satisfaction. Therefore, we measured NAC sensitivity after NSM and compared patient satisfaction as well as body image after SSM with NSM...
August 2016: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/26075692/electroconvulsive-therapy-under-general-anesthesia-with-cisatracurium-laryngeal-mask-airways-and-bispectral-index
#10
Cai-Cai Liu, Xiao-Yan Qian, Jian-Xiong An, Zeng-Lei Yu, Jian-Ping Wu, Hui Wen, Zong-Xin Cao, Yong Wang, Qi-Wu Fang, John P Williams
OBJECTIVES: Electroconvulsive therapy (ECT) has dramatically reduced musculoskeletal complications when carried out with muscle relaxants under general anesthesia. However, seizure quality can be affected by the depth of anesthesia and choice of anesthetic agent. The purpose of this study was to describe a general anesthetic technique for ECT by using laryngeal mask, bispectral index (BIS), and muscle relaxant monitoring. METHODS: Twenty-one patients, between ages 18 and 70 years (American Society of Anesthesiologists physical status I-III), who underwent a total of 89 sessions of ECT were examined in a retrospective study...
March 2016: Journal of ECT
https://www.readbyqxmd.com/read/25944463/use-of-bis-vista-bilateral-monitor-for-diagnosis-of-intraoperative-seizures-a-case-report
#11
F Iturri Clavero, G Tamayo Medel, K de Orte Sancho, A González Uriarte, A Iglesias Martínez, A Martínez Ruíz
Changes in BIS (bispectral index) VISTA bilateral monitoring system associated with intraoperative episodes of generalized and focal seizures, during total intravenous anesthesia for resection of a left frontal parasagittal meningioma, are herein described.
December 2015: Revista Española de Anestesiología y Reanimación
https://www.readbyqxmd.com/read/25943998/an-exploratory-study-of-the-bilateral-bispectral-index-for-pain-detection-in-traumatic-brain-injured-patients-with-altered-level-of-consciousness
#12
Caroline Arbour, Céline Gélinas, Carmen G Loiselle, Patricia Bourgault
INTRODUCTION: Many patients with a traumatic brain injury (TBI) cannot communicate because of altered level of consciousness. Although observation of pain behaviors (e.g., frowning) is recommended for pain assessment in nonverbal populations, they are attenuated and sometimes even suppressed in patients with TBI receiving high doses of sedatives. This study explored the potential utility of the bilateral bispectral index system (BIS) for pain detection in critically ill adults with TBI and altered level of consciousness...
June 2015: Journal of Neuroscience Nursing: Journal of the American Association of Neuroscience Nurses
https://www.readbyqxmd.com/read/25928189/intraoperative-burst-suppression-is-associated-with-postoperative-delirium-following-cardiac-surgery-a-prospective-observational-study
#13
Martin Soehle, Alexander Dittmann, Richard K Ellerkmann, Georg Baumgarten, Christian Putensen, Ulf Guenther
BACKGROUND: Postoperative delirium (POD) occurs frequently after cardiac surgery and is associated with increased morbidity and mortality. We analysed whether perioperative bilateral BIS monitoring may detect abnormalities before the onset of POD in cardiac surgery patients. METHODS: In a prospective observational study, 81 patients undergoing cardiac surgery were included. Bilateral Bispectral Index (BIS)-monitoring was applied during the pre-, intra- and postoperative period, and BIS, EEG Asymmetry (ASYM), and Burst Suppression Ratio (BSR) were recorded...
2015: BMC Anesthesiology
https://www.readbyqxmd.com/read/25904686/increased-oxidative-stress-is-related-to-disease-severity-in-the-als-motor-cortex-a-pet-study
#14
Masamichi Ikawa, Hidehiko Okazawa, Tetsuya Tsujikawa, Akiko Matsunaga, Osamu Yamamura, Tetsuya Mori, Tadanori Hamano, Yasushi Kiyono, Yasunari Nakamoto, Makoto Yoneda
OBJECTIVE: To investigate cerebral oxidative stress based on an over-reductive state caused by mitochondrial dysfunction and its relationship to disease severity in patients with amyotrophic lateral sclerosis (ALS) using PET with [(62)Cu]diacetyl-bis(N(4)-methylthiosemicarbazone) ((62)Cu-ATSM). METHODS: Twelve patients with ALS and 9 age-matched healthy controls underwent a 20-minute dynamic brain PET scan after (62)Cu-ATSM injection. The standardized uptake value (SUV) images obtained from the last 10 minutes of frames were normalized by the global mean (nSUV)...
May 19, 2015: Neurology
https://www.readbyqxmd.com/read/25756691/differential-role-of-estrogen-receptor-modulators-in-depression-like-behavior-and-memory-impairment-in-rats-with-postmenopausal-diabetes
#15
Seema Bansal, Kanwaljit Chopra
OBJECTIVE: Diabetes and menopause are frequent comorbidities. The objective of the present study was to delineate the effects of nonselective and selective estrogen receptor (ER) agonists (α and β) on cognitive function and depressive behavior in ovariectomized diabetic (Ovx-Dia) rats. METHODS: Bilateral ovariectomy was performed in female Sprague-Dawley rats (200-250 g), and streptozotocin was used to induce experimental diabetes. Rats were administered (10 μg/kg SC) a nonselective ER agonist, 17β-estradiol (E2); a selective ER-α agonist, propionitrile (PPT; 4,4',4″-(4-propyl-[1H] pyrazole-1,3,5-triyl) tris phenol); and a selective ER-β agonist, 2,3-bis(4-hydroxyphenyl)-propionitrile (DPN) for 4 weeks after streptozotocin injection...
October 2015: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/25534331/effect-of-transversus-abdominis-plane-block-on-cost-of-laparoscopic-cholecystectomy-anesthesia
#16
Serdar Kokulu, Elif Doğan Bakı, Emre Kaçar, Ahmet Bal, Hasan Şenay, Kübra Demir Üstün, Sezgin Yılmaz, Yüksel Ela, Remziye Gül Sıvacı
BACKGROUND: Use of transversus abdominis plane (TAP) block for postoperative analgesia is continuously increasing. However, few studies have investigated intraoperative effects of TAP block. We aimed to study the effects of TAP block in terms of cost-effectiveness and consumption of inhalation agents. MATERIAL AND METHODS: Forty patients undergoing laparoscopic cholecystectomy were enrolled in this study. Patients were randomly divided into 2 groups: Group 1 (n=20) patients received TAP block and Group 2 (n=20) patients did not receive TAP block...
2014: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/25456522/obsessive-compulsivity-and-working-memory-are-associated-with-differential-prefrontal-cortex-and-insula-activation-in-adolescents-with-a-recent-diagnosis-of-an-eating-disorder
#17
Samantha J Brooks, Linda Solstrand Dahlberg, Ingemar Swenne, Marianne Aronsson, Sanaz Zarei, Lina Lundberg, Josefin A Jacobsson, Mathias Rask-Andersen, Helena Salonen-Ros, Agneta Rosling, Elna-Marie Larsson, Helgi B Schiöth
The role of rumination at the beginning of eating disorder (ED) is not well understood. We hypothesised that impulsivity, rumination and restriction could be associated with neural activity in response to food stimuli in young individuals with eating disorders (ED). We measured neural responses with functional magnetic resonance imaging (fMRI), tested working memory (WM) and administered the eating disorders examination questionnaire (EDE-Q), Barratt impulsivity scale (BIS-11) and obsessive-compulsive inventory (OCI-R) in 15 adolescent females with eating disorder not otherwise specified (EDNOS) (mean age 15 years) and 20 age-matched healthy control females...
December 30, 2014: Psychiatry Research
https://www.readbyqxmd.com/read/25350686/three-steps-in-one-pot-synthesis-of-linear-bilateral-extended-2-2-6-2%C3%A2-terpyridineruthenium-ii-complexes
#18
Janis Veliks, Olivier Blacque, Jay S Siegel
Metal complexes of linear bilateral extended 2,2':6',2″-terpyridine [2,6-bis(2-substituted furo[2,3-c]pyridin-5-yl)pyridine] are topological tridentate analogues of 5,5'-functionalized 2,2'-bipyridine. The present methodology provides access to linear bilateral extended 2,2':6',2″-terpyridineruthenium(II) complexes starting from 5,5″-bis(methoxymethoxy)-4,4″-bis(substituted ethynyl)-2,2':6',2″-terpyridines via one-pot cleavage of the methoxymethyl (MOM) protecting group, cycloisomerization, and metal complexation in the presence of Ru(DMSO)4Cl2...
November 17, 2014: Inorganic Chemistry
https://www.readbyqxmd.com/read/25069642/free-radical-scavenging-activity-and-neuroprotective-potentials-of-d138-one-cu-ii-zn-ii-schiff-base-complex-derived-from-n-n-bis-2-hydroxynaphthylmethylidene-1-3-propanediamine
#19
Che Wang, Zheng-Xu Cai, Zhong-Lu You, Hui-Shu Guo, De-Jing Shang, Xiao-Ling Wang, Liang Zhang, Li-Jie Ma, Jun Tan, Wei-Dong Le, Song Li
There is increasing evidence that free radicals play an important role in neuronal damages induced by diabetes mellitus or cerebral ischemia insults. Antioxidants with free radical scavenging activities have been shown to be beneficial and neuroprotective for these pathological conditions. Here, we report free radical scavenging activity and neuroprotective potential of D138, one copper(II)/zinc(II) Schiff-base complex derived from N,N'-2(2-hydroxynaphthylmethylidene)-1,3-propanediamine. The data from three in vitro assays, 2,2-diphenyl-1-picrylhydrazyl assay, nitro blue tetrazolium assay and hydroxyl radical scavenging assay, indicated that D138 presented a potent free radical scavenging activity...
September 2014: Neurochemical Research
https://www.readbyqxmd.com/read/24978685/-phoenix-jaw-bone-regeneration-of-the-necrotic-mandible-between-pathological-fractures-an-unusual-but-evocative-course-of-bisphosphonate-related-osteonecrosis
#20
Tomoaki Imai, Masahiro Michizawa
Management of advanced bisphosphonate-related osteonecrosis of the jaw, particularly in cases of pathological fractures with extraoral fistulas, is a challenging responsibility for craniomaxillofacial specialists. Although a periosteal reaction is occasionally observed in cases with extensive sequestra, few reports have documented circumferential periosteal osseous formation resulting in bone repair. We present the case of a 78-year-old woman who was treated for breast cancer and received intravenous bisphosphonates...
July 2014: Journal of Craniofacial Surgery
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