keyword
MENU ▼
Read by QxMD icon Read
search

LGA

keyword
https://www.readbyqxmd.com/read/28930827/comparative-efficacy-and-safety-of-oral-antidiabetic-drugs-and-insulin-in-treating-gestational-diabetes-mellitus-an-updated-prisma-compliant-network-meta-analysis
#1
Hui-Ling Liang, Shu-Juan Ma, Yan-Ni Xiao, Hong-Zhuan Tan
BACKGROUND: The safety and efficacy of different drugs in treatment of gestational diabetes mellitus (GDM) patients who could not maintain normal glucose level only through diet and exercise remains to be debated. We performed this network meta-analysis (NAM) to compare and rank different antidiabetic drugs in glucose level control and pregnancy outcomes in GDM patients. METHODS: We searched PubMed, Cochrane Library, Web of Science, and Embase up to December 31, 2016...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28919080/regulation-of-glutamate-transporter-1-glt-1-gene-expression-by-cocaine-self-administration-and-withdrawal
#2
Ronald Kim, Marian T Sepulveda-Orengo, Kati L Healey, Emily A Williams, Kathryn J Reissner
Downregulation of the astroglial glutamate transporter GLT-1 is observed in the nucleus accumbens (NAc) following administration of multiple drugs of abuse. The decrease in GLT-1 protein expression following cocaine self-administration is dependent on both the amount of cocaine self-administered and the length of withdrawal, with longer access to cocaine and longer withdrawal periods leading to greater decreases in GLT-1 protein. However, the mechanism(s) by which cocaine downregulates GLT-1 protein remains unknown...
September 14, 2017: Neuropharmacology
https://www.readbyqxmd.com/read/28905320/genetic-algorithm-with-a-crossover-elitist-preservation-mechanism-for-protein-ligand-docking
#3
Boxin Guan, Changsheng Zhang, Jiaxu Ning
Protein-ligand docking plays an important role in computer-aided pharmaceutical development. Protein-ligand docking can be defined as a search algorithm with a scoring function, whose aim is to determine the conformation of the ligand and the receptor with the lowest energy. Hence, to improve an efficient algorithm has become a very significant challenge. In this paper, a novel search algorithm based on crossover elitist preservation mechanism (CEP) for solving protein-ligand docking problems is proposed. The proposed algorithm, namely genetic algorithm with crossover elitist preservation (CEPGA), employ the CEP to keep the elite individuals of the last generation and make the crossover more efficient and robust...
September 13, 2017: AMB Express
https://www.readbyqxmd.com/read/28904700/descriptive-epidemiology-of-a-cholera-outbreak-in-kaduna-state-northwest-nigeria-2014
#4
Ibrahim Baffa Sule, Mohammed Yahaya, Abubakar Ahmed Aisha, Ahmed Datti Zainab, Bajoga Ummulkhulthum, Patrick Nguku
INTRODUCTION: Cholera is an acute gastrointestinal infection caused by Vibrio cholerae, which may lead to severe dehydration and death if not treated. This analysis is aimed at highlighting the magnitude, pattern and trend of cholera outbreak that occurred in Kaduna State in 2014. METHODS: We obtained the 2014 cholera line-list from the Kaduna State Disease Surveillance and Notification officer (DSNO). We described the outbreaks in time, place and person using Epi-info 7 and Health Mapper...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28899746/performance-of-five-research-domain-automated-wm-lesion-segmentation-methods-in-a-multi-center-ms-study
#5
Alexandra de Sitter, Martijn D Steenwijk, Aurélie Ruet, Adriaan Versteeg, Yahou Liu, Ronald A van Schijndel, Petra J W Pouwels, Iris D Kilsdonk, Keith S Cover, Bob W van Dijk, Stefan Ropele, Maria A Rocca, Marios Yiannakas, Mike P Wattjes, Soheil Damangir, Giovanni B Frisoni, Jaume Sastre-Garriga, Alex Rovira, Christian Enzinger, Massimo Filippi, Jette Frederiksen, Olga Ciccarelli, Ludwig Kappos, Frederik Barkhof, Hugo Vrenken
BACKGROUND AND PURPOSE: In vivoidentification of white matter lesions plays a key-role in evaluation of patients with multiple sclerosis (MS). Automated lesion segmentation methods have been developed to substitute manual outlining, but evidence of their performance in multi-center investigations is lacking. In this work, five research-domain automated segmentation methods were evaluated using a multi-center MS dataset. METHODS: 70 MS patients (median EDSS of 2...
September 9, 2017: NeuroImage
https://www.readbyqxmd.com/read/28899308/demographic-and-geographical-risk-factors-for-gonorrhoea-and-chlamydia-in-greater-western-sydney-2003-2013
#6
Marianne Gale, Andrew Hayen, George Truman, Rick Varma, Bradley L Forssman, C Raina MacIntyre
INTRODUCTION: Notification rates of sexually transmitted infections (STIs) have increased in New South Wales as elsewhere in Australia. Understanding trends in chlamydia and gonorrhoea notifications at smaller geographical areas may assist public health efforts to deliver targeted STI interventions. METHODS: Routinely collected disease notification data from 2 local health districts within the greater Western Sydney area were analysed. De-identified notifications of gonorrhoea and chlamydia were extracted for people aged over 15 years during the period 1 January 2003 to 31 December 2013...
June 30, 2017: Communicable Diseases Intelligence Quarterly Report
https://www.readbyqxmd.com/read/28895044/effect-of-zinc-supplementation-on-growth-performance-intestinal-development-and-intestinal-barrier-related-gene-expression-in-pekin-ducks
#7
Min Wen, Hua Zhao, Guangmang Liu, Xiaoling Chen, Bing Wu, Gang Tian, Jingyi Cai, Gang Jia
The current study was conducted to investigate the effect of zinc supplementation on the growth performance, intestinal morphology, and the transcription of the barrier function related genes in Pekin ducks. Seven-hundred and sixty-eight 1-day-old Pekin ducks were randomly assigned into six dietary treatments. Each treatment had eight replicates with 16 ducks per replicates. The ducks were fed either a corn-soybean meal basal diet or basal diets supplemented with 15, 30, 60, 120, and 240 mg zinc/kg from zinc sulfate...
September 11, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28891549/effects-of-health-care-services-and-commodities-cost-on-the-patients-at-the-primary-health-facilities-in-zaria-metropolis-north-western-nigeria
#8
O Adegboyega, K Abioye
INTRODUCTION: The payment for health-care services is a major problem for many poor patients in developing nations. The aim of the study was to examine the cost of services and commodities and how these affect the patients who utilizes the primary health-care centers in Zaria, North western Nigeria. METHODOLOGY: A descriptive cross-sectional survey of six primary health-care facilities in Zaria metropolis, namely Baban dodo, Tudun Wada, Magajiya PHCs from Zaria local government areas (LGA) and Samaru, Kwata, and Dogarawa PHCs from Sabon Gari LGA, was carried out...
August 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/28885837/selective-derivatization-of-a-hexaphosphane-from-functionalization-of-white-phosphorus
#9
Felix Hennersdorf, Julia Froetschel, Jan J Weigand
The reaction of LGa (L = Dipp(4-(Dipp-imino)pent-2-en-2-yl)amide; Dipp: 2,6-diisopropylphenyl) and white phospho-rus was revisited. A plethora of unprecedented polyphosphanes besides the known mono-inserted product LGaP4 (1) is observed. An optimized synthesis of the hitherto unknown hexaphosphane (LGa)2P6 (3) is presented and its subsequent selective derivatization with Brønsted acids, MeOTf, Ph2ECl (E = P, As) and NaOCP providing access to a wealth of functionalized hexa- and heptaphosphanes.
September 8, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28881305/the-association-between-cooking-oil-fume-exposure-during-pregnancy-and-birth-weight-a-prospective-mother-child-cohort-study
#10
Lingling Wang, Weiyue Hu, Quanquan Guan, Guizhen Du, Ting Chen, Wei Wu, Yun Wang, Xinru Wang, Yankai Xia
Effects of indoor air pollution on neonatal birth weight has been studied for many years. In China, cooking oil fumes are important parts of indoor air pollution. However, whether cooking oil fume exposure during pregnancy affects birth weight in China remains poorly understood. The objective of this study was to examine the association between pregnancy exposure to cooking oil fumes and birth weight in a newly established prospective mother-child cohort in China. We finally included 1420 pregnant women from 2013 to 2015 and follow up for one year until the offspring was born...
September 4, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28879832/supermarket-access-transport-mode-and-bmi-the-potential-for-urban-design-and-planning-policy-across-socio-economic-areas
#11
Maureen Murphy, Mohammad Javad Koohsari, Hannah Badland, Billie Giles-Corti
OBJECTIVE: To investigate dietary intake, BMI and supermarket access at varying geographic scales and transport modes across areas of socio-economic disadvantage, and to evaluate the implementation of an urban planning policy that provides guidance on spatial access to supermarkets. DESIGN: Cross-sectional study used generalised estimating equations to investigate associations between supermarket density and proximity, vegetable and fruit intake and BMI at five geographic scales representing distances people travel to purchase food by varying transport modes...
September 7, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/28868781/long-term-outcomes-for-large-for-gestational-age-infants-born-at-term
#12
Amina Z Khambalia, Charles S Algert, Jennifer R Bowen, Rebecca J Collie, Christine L Roberts
AIM: Large for gestational age (LGA) babies have increased risks for short-term outcomes such as shoulder dystocia, neonatal hypoglycaemia and longer hospital stay. Little is known of long-term health, development and educational outcomes of LGA babies. The aim of this study was to determine the long-term health, mortality, development and educational outcomes for infants born LGA at term. METHODS: A population-based record linkage study of live singletons born at term (37-41 weeks of gestation) in New South Wales, Australia, from 2001 to 2006...
September 2017: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/28866958/perinatal-outcome-of-pregnancies-complicates-with-extreme-birth-weights-at-term
#13
Uri Chavkin, Tamar Wainstock, Eyal Sheiner, Ruslan Sergienko, Asnat Walfisch
OBJECTIVE: To investigate whether an abnormal birthweight at term, either small for gestational age (SGA, < 5(th) centile for gestational age), or large for gestational age (LGA, > 95(th) centile for gestational age), is a risk factor for perinatal complications as compared with birthweight appropriate for gestational age (AGA). METHODS: A population based retrospective cohort analysis of all singleton pregnancies delivered between 1991 and 2014 at Soroka Medical Center...
September 3, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28864965/pharmacological-management-of-gestational-diabetes-mellitus
#14
Geetha Mukerji, Denice S Feig
Gestational diabetes mellitus (GDM) is associated with an increased risk of adverse pregnancy outcomes in the setting of poor glycemic control. The initial management for GDM includes intensive lifestyle modification, which often requires behavioral and nutritional changes to optimize glycemic control. Pharmacotherapy for GDM is initiated when glycemic targets are not met. The rapid-acting bolus analogues aspart and lispro achieve postprandial targets with less hypoglycemia compared to regular insulin, with similar fetal outcomes...
September 2, 2017: Drugs
https://www.readbyqxmd.com/read/28845614/early-pregnancy-weight-gain-exerts-the-strongest-effect-on-birth-weight-posing-a-critical-time-to-prevent-childhood-obesity
#15
Nicholas T Broskey, Peng Wang, Nan Li, Junhong Leng, Weiqin Li, Leishen Wang, L Anne Gilmore, Gang Hu, Leanne M Redman
OBJECTIVE: Gestational weight gain (GWG) is associated with infant birth weight and childhood obesity; however, the patterns of GWG on infant birth weight are poorly understood. METHODS: This analysis in 16,218 mother-child dyads from Tianjin, China, determined the risk of infant size at birth according to GWG occurring throughout the first and second trimester (early GWG) or during the third trimester (late GWG), according to maternal prepregnancy BMI and the 2009 Institute of Medicine recommendations...
September 2017: Obesity
https://www.readbyqxmd.com/read/28835142/a-retrospective-study-comparing-outcomes-in-a-midwestern-us-population-after-introduction-of-iadpsg-guidelines-for-gestational-diabetes
#16
Gene T Lee, Megha Teeka Satyan, Jill D Grothusen, Kelsi M Drummond, Grace Hagen, Crystal Brown, Catherine L Satterwhite
OBJECTIVE: More evidence is required to endorse the 1-step approach for gestational diabetes mellitus (GDM) for clinical practice. Since 2010, our department has pragmatically allowed faculty to selfselect the guidelines they use to screen and diagnose GDM. We sought to compare the maternal and neonatal outcomes from these two simultaneous cohorts. STUDY DESIGN: We performed a retrospective cohort study of all singleton pregnancies delivered between October 2011-November 2013 at our hospital...
August 24, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28830259/clinical-significance-of-low-result-of-1-hour-50-g-glucose-challenge-test-in-pregnant-women
#17
Nozomi Oawada, Shigeru Aoki, Kentaro Sakamaki, Soichiro Obata, Kazuo Seki, Fumiki Hirahara
OBJECTIVE: To examine the effect of low glucose value on the 1-hour 50-g Glucose Challenge Test (GCT) on neonatal body weight in low-risk Asian singleton pregnant women. METHOD: We retrospectively analyzed women who delivered a singleton neonate at term at a tertiary center and underwent GCT at 24-28 weeks of gestation between June 2001 and June 2015. Low GCT group was defined as < 75 mg/dL, and 75-139 mg/dL were control. We compared these two groups of maternal characteristics, small for gestational age neonate (SGA), large for gestational age neonate (LGA), low-birth weight, and macrosomia...
August 22, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28812595/compulsive-like-sufentanil-vapor-self-administration-in-the-rat
#18
Janaina Cm Vendruscolo, Brendan J Tunstall, Stephanie A Carmack, Brooke E Schmeichel, Emily G Lowery-Gionta, Maury Cole, Olivier George, Sophia Vandewater, Michael Taffe, George F Koob, Leandro F Vendruscolo
Opioid misuse is at historically high levels in the United States, with inhalation (ie, smoking, and vaping) being one of the most common routes of consumption. We developed and validated a novel preclinical model of opioid self-administration by inhalation that does not require surgery and reliably produces somatic and motivational signs of dependence. Rats were trained to perform an operant response (nosepoke) to receive 10 s of vaporized sufentanil, a potent opioid, in 2 h daily sessions. Rats readily and concentration-dependently self-administered vaporized sufentanil...
August 16, 2017: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28803256/surface-structure-changes-of-pathological-placenta-tissue-observed-using-scanning-electron-microscopy-a-pilot-study
#19
Rafał Bobiński, Anna Pielesz, Wioletta Waksmańska, Ewa Sarna, Izabela Ulman-Włodarz, Justyna Kania, Monika Mikulska, Agnieszka Turbiarz
Structural changes within the placenta are observed in the course of pathological pregnancy. The aim of the study was to perform initial assessment of morphological features of placenta. The analysis was conducted by Scanning Electron Microscopy. Samples of placenta of women who delivered neonates appropriate for gestational age were characterized by a homogenous surface texture with natural corrugation. The surface of IUGR placenta from the group of mothers with pregnancy induced hypertension was definitely heterogeneous - noticeable swelling of tissue surface was observed...
2017: Acta Biochimica Polonica
https://www.readbyqxmd.com/read/28796674/neonatal-morbidity-of-small-and-large-for-gestational-age-neonates-born-at-term-in-uncomplicated-pregnancies
#20
Suneet P Chauhan, Madeline Murguia Rice, William A Grobman, Jennifer Bailit, Uma M Reddy, Ronald J Wapner, Michael W Varner, John M Thorp, Kenneth J Leveno, Steve N Caritis, Mona Prasad, Alan T N Tita, George Saade, Yoram Sorokin, Dwight J Rouse, Jorge E Tolosa
OBJECTIVE: To compare morbidity among small-for-gestational-age (SGA; birth weight less than the 10th percentile for gestational age), appropriate-for-gestational-age (AGA; birth weight 10th to 90th percentile; reference group), and large-for-gestational-age (LGA; birth weight greater than the 90th percentile) neonates in apparently uncomplicated pregnancies at term (37 weeks of gestation or greater). METHODS: This secondary analysis, derived from an observational obstetric cohort of 115,502 deliveries, included women with apparently uncomplicated pregnancies of nonanomalous singletons who had confirmatory ultrasound dating no later than the second trimester and who delivered between 37 0/7 and 42 6/7 weeks of gestation...
September 2017: Obstetrics and Gynecology
keyword
keyword
105799
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"