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https://www.readbyqxmd.com/read/28092059/the-effects-of-race-and-ethnicity-on-the-risk-of-large-for-gestational-age-newborns-in-women-without-gestational-diabetes-by-prepregnancy-body-mass-index-categories
#1
Nhial T Tutlam, Yun Liu, Erik J Nelson, Louise H Flick, Jen Jen Chang
Objectives Children born large for gestational age (LGA) are at risk of numerous adverse outcomes. While the racial/ethnic disparity in LGA risk has been studied among women with Gestational Diabetes Mellitus (GDM), the independent effect of race on LGA risk by maternal prepregnancy BMI is still unclear among women without GDM. Therefore, the objective of this study was to assess the association between maternal race/ethnicity and LGA among women without GDM. Methods This was a population-based cohort study of 2,842,278 singleton births using 2012 U...
January 13, 2017: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/28088620/relations-between-neighbourhood-socioeconomic-status-and-birth-outcomes-are-mediated-by-maternal-weight
#2
Zahra M Clayborne, Gerald F Giesbrecht, Rhonda C Bell, Lianne M Tomfohr-Madsen
Lower neighbourhood-level socioeconomic status (SES) has been repeatedly associated with an increased risk of adverse birth outcomes, even after controlling for individual-level SES. Few studies have empirically assessed potential mechanisms underlying the associations. The objectives of this study were to (1) examine relations between neighbourhood SES and birth outcomes, and (2) explore if maternal weight variables mediated these relations. Data came from a provincial prospective pregnancy cohort study in Canada...
December 29, 2016: Social Science & Medicine
https://www.readbyqxmd.com/read/28058464/associations-between-high-birth-weight-being-large-for-gestational-age-and-high-blood-pressure-among-adolescents-a-cross-sectional-study
#3
Renata Kuciene, Virginija Dulskiene, Jurate Medzioniene
PURPOSE: Low birth weight and being small for gestational age are associated with increased risk of cardiometabolic diseases. However, the results from the studies examining the associations between high birth weight (HBW), being large for gestational age (LGA), and high blood pressure (HBP) are inconsistent. The aim of this study was to evaluate the associations between HBW and being LGA alone and in combinations with body mass index (BMI) categories in adolescence and HBP among Lithuanian adolescents aged 12-15 years...
January 5, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28044196/maternal-fasting-glycemia-and-adverse-pregnancy-outcomes-in-a-mediterranean-population
#4
G Sesmilo, E Meler, V Perea, I Rodríguez, A Rodríguez-Melcón, M Guerrero, B Serra
AIMS: The hyperglycemia and adverse pregnancy outcome study demonstrated a continuous association between fasting plasma glucose (FPG) levels below those diagnostic of diabetes and adverse neonatal outcomes. We aimed to investigate whether the same association was found in a Mediterranean population. METHODS: A retrospective analysis of singleton pregnancies attended at our Hospital between 2008 and 2015 (n = 5203). FPG was evaluated in the second trimester, and it was divided into 7 categories (1 < 75, 2 75-79, 3 80-84, 4 85-89, 5 90-94, 6 95-99 and 7 100-124 mg/dL)...
January 3, 2017: Acta Diabetologica
https://www.readbyqxmd.com/read/28034474/iga-vasculitis-henoch-sch%C3%A3-nlein-case-definition-andguidelines-for-data-collection-analysis-and-presentation-of-immunisation-safety-data
#5
Andreas Woerner, Christoph Rudin, Caterina Bonetto, Carmela Santuccio, Seza Ozen, Robert P Wise, Rebecca Chandler, Jan Bonhoeffer
No abstract text is available yet for this article.
December 26, 2016: Vaccine
https://www.readbyqxmd.com/read/28028895/characterization-of-sox9-overexpressing-human-umbilical-cord-blood-derived-mesenchymal-stem-cells-based-engineered-cartilage-both-in-vitro-and-in-vivo
#6
Xiao-Li Li, Jun Zhang, Hua-Nan Luo, Xiaoyan Zhao, A-Ling Zhang, Zheng-Hui Wang
The source of seed cells is a critical factor for tissue engineering . The goal of this study was to evaluate the chondrogenesis of Sox9-overexpressing human umbilical cord mesenchymal stem cells (hUCMSCs) seeded onto bone matrix gelatin (BMG)/fibrin hybrid scaffolds both in vitro and in vivo. hUCMSCs were stably transfected with Sox9-expressing plasmid and grown on the three-dimensional BMG/fibrin hybrid scaffold for 8 weeks. Scanning electron microscopy and histochemistry were performed. The hUCMSC-loaded scaffolds were implanted into the subcutaneous layer of immunocompetent rats and chondrogenesis and host immune responses were monitored for 8 weeks...
December 28, 2016: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/28027694/awareness-and-perception-of-strabismus-among-the-youths-and-women-of-child-bearing-age-in-a-local-government-in-south-western-nigeria
#7
Olubunmi Bodunde, Tamramat Runsewe-Abiodun, Adekunle Alabi, Janet Adetunji, Michael Olowonyo, Bolanle Adefuye
Purpose To determine the awareness and perception of strabismus among the youths and women of child-bearing age in Ikenne Local Government Area (LGA) of Ogun State, South Western Nigeria. Methodology Fifteen focus group discussions (FGDs) were carried out in the LGA on the perceptions and attitudes of people to strabismus. Their responses were tape-recorded and later transcribed. A thematic phenomenological approach was used for the analysis. Result A total of 139 people participated in the FGDs, with a male:female ratio of 1:∼4...
January 1, 2016: International Quarterly of Community Health Education
https://www.readbyqxmd.com/read/28018853/mri-flair-lesion-segmentation-in-multiple-sclerosis-does-automated-segmentation-hold-up-with-manual-annotation
#8
Christine Egger, Roland Opfer, Chenyu Wang, Timo Kepp, Maria Pia Sormani, Lothar Spies, Michael Barnett, Sven Schippling
INTRODUCTION: Magnetic resonance imaging (MRI) has become key in the diagnosis and disease monitoring of patients with multiple sclerosis (MS). Both, T2 lesion load and Gadolinium (Gd) enhancing T1 lesions represent important endpoints in MS clinical trials by serving as a surrogate of clinical disease activity. T2- and fluid-attenuated inversion recovery (FLAIR) lesion quantification - largely due to methodological constraints - is still being performed manually or in a semi-automated fashion, although strong efforts have been made to allow automated quantitative lesion segmentation...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28012695/birth-weight-for-gestational-age-anthropometric-measures-and-cardiovascular-disease-markers-in-children
#9
Stefan Kuhle, Bryan Maguire, Nicole Ata, Natasha MacInnis, Linda Dodds
OBJECTIVE: To examine the association of birth weight for gestational age with anthropometric measures and cardiometabolic markers in a population-based sample of Canadian children. STUDY DESIGN: The study used data from 2016 children aged 6-12 years from the first 2 cycles of the Canadian Health Measures Survey, a population-based survey of Canadian residents. The main exposure was birth weight for gestational age (small [SGA], large [LGA], and appropriate for gestational age [AGA])...
December 21, 2016: Journal of Pediatrics
https://www.readbyqxmd.com/read/28004267/effect-of-delivery-mode-on-neonatal-outcome-among-preterm-infants-an-observational-study
#10
Iris Holzer, Rainer Lehner, Robin Ristl, Peter W Husslein, Angelika Berger, Alex Farr
BACKGROUND: The optimal mode of delivery as a predictor for outcomes in preterm infants is under debate. The purpose of this study was to evaluate the effect of the delivery mode on neonatal outcome among preterm infants in different birthweight categories. METHODS: A retrospective analysis of singleton preterm deliveries from 23 + 0 to 33 + 6 gestational weeks was performed. Infants were categorized based on birthweight as large for gestational age (LGA), appropriate for gestational age (AGA) and small for gestational age (SGA)...
December 21, 2016: Wiener Klinische Wochenschrift
https://www.readbyqxmd.com/read/28002314/association-between-polycystic-ovary-syndrome-and-the-risk-of-pregnancy-complications-a-prisma-compliant-systematic-review-and-meta-analysis
#11
Hai-Feng Yu, Hong-Su Chen, Da-Pang Rao, Jian Gong
BACKGROUND: Polycystic ovary syndrome (PCOS) is inconsistently associated with increased risk of adverse pregnancy outcomes. The purpose of this meta-analysis was to summarize the evidence regarding the strength of the association between pregnancy in women with PCOS and pregnancy complications. METHODS: We systematically searched PubMed, EmBase, and the Cochrane Library to identify observational studies up to January 2016. The primary focus was pregnancy outcomes, including gestational diabetes mellitus (GDM), preeclampsia, pregnancy-induced hypertension (PIH), preterm delivery, cesarean delivery, oligohydramnios, and polyhydramnios...
December 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27942798/are-the-institute-of-medicine-weight-gain-targets-applicable-in-women-with-gestational-diabetes-mellitus
#12
Tang Wong, Robyn A Barnes, Glynis P Ross, Ngai W Cheung, Jeff R Flack
AIMS/HYPOTHESIS: Our aim was to study the relationship between excessive gestational weight gain (GWG) according to Institute of Medicine (IOM) targets and perinatal outcomes, and examine whether modifying targets may improve outcomes in women with gestational diabetes mellitus (GDM). METHODS: This was a retrospective cohort study of all GDM pregnancies from 1992 to 2013. ORs were calculated for associations between excessive GWG (EGWG) using IOM targets and adverse pregnancy outcomes...
December 9, 2016: Diabetologia
https://www.readbyqxmd.com/read/27936018/stillbirths-at-term-case-control-study-of-risk-factors-growth-status-and-placental-histology
#13
Federico Mecacci, Caterina Serena, Laura Avagliano, Mauro Cozzolino, Eleonora Baroni, Marianna Pina Rambaldi, Serena Simeone, Francesca Castiglione, Gian Luigi Taddei, Gaetano Bulfamante
OBJECTIVE: To investigate the proportion of stillbirths at term associated with abnormal growth using customized birth weight percentiles and to compare histological placental findings both in underweight stillborn fetuses and in live births. METHODS: A retrospective case-control study of 150 singleton term stillbirths. The livebirth control groups included 586 cases of low-risk pregnancies and 153 late fetal growth restriction fetuses. Stillbirths and livebirths from low-risk pregnancies were classified using customized standards for fetal weight at birth, as adequate for gestational age (AGA; 10-90th percentile), small (SGA; <10th percentile) or large for gestational age (LGA; >90th percentile)...
2016: PloS One
https://www.readbyqxmd.com/read/27935148/customized-versus-population-based-growth-charts-to-identify-neonates-at-risk-of-adverse-outcomes-a-systematic-review-and-bayesian-meta-analysis-of-observational-studies
#14
REVIEW
Giuseppe Chiossi, Claudia Pedroza, Maged M Costantine, Van Thi Thanh Truong, Giancarlo Gargano, George R Saade
OBJECTIVE: To compare the effectiveness of customized versus population-based growth charts for prediction of adverse pregnancy outcomes. METHODS: we searched MEDLINE, http://ClinicalTrials.gov and the Cochrane library up to May 31(st) 2016 to identify interventional and observational studies comparing adverse outcomes among large (LGA) and small (SGA) for gestational age neonates, when classified with customized versus population-based growth charts. We studied perinatal mortality and NICU admission among both SGA and LGA neonates, IUFD and neonatal mortality among SGA, shoulder dystocia, 3(rd) and 4(th) degree perineal lacerations, as well as neonatal hypoglycemia among LGA...
December 9, 2016: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27930504/aberrant-hepatic-arteries-running-through-pancreatic-parenchyma-encountered-during-pancreatoduodenectomy-two-rare-case-reports-and-strategies-for-surgical-treatment
#15
Lei Wang, Jianwei Xu, Dong Sun, Zongli Zhang
BACKGROUND: Aberrant hepatic arteries (HAs) encountered during pancreatoduodenectomy are difficult to manage. MEHTODS: Two cases with rare types of aberrant HA running through the pancreatic parenchyma were reviewed. RESULTS: The first case, a 68-year-old man, was admitted with obstructive jaundice. A tumor of the pancreatic head and aberrant HAs were suspected on computed tomography (CT) scan. At laparotomy, a new variation was identified; namely, 2 aberrant arteries-a right replaced HA and middle HA (RMHA) that both originated from the superior mesenteric artery (SMA) and ran via intrapancreatic paths posterior and anterior to the pancreatic head, respectively...
December 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27926975/large-for-gestational-age-infants-and-adverse-outcomes-among-uncomplicated-pregnancies-at-term
#16
Hector Mendez-Figueroa, Van Thi Thanh Truong, Claudia Pedroza, Suneet P Chauhan
Background While traumatic delivery with large for gestational age (LGA; birth weight above 90%) is acknowledged, there is paucity of data regarding other morbidity and mortality associated with LGA. Our hypothesis was that compared with appropriate for gestational age (AGA), LGA have a significantly higher rate of composite neonatal morbidity (CNM). Objective Our objective was to compare the CNM among uncomplicated LGA versus AGA at term (37 weeks or more) among all available Maternal-Fetal Medicine Units (MFMU) databases...
December 7, 2016: American Journal of Perinatology
https://www.readbyqxmd.com/read/27918227/mapping-trachoma-in-kaduna-state-nigeria-results-of-23-local-government-area-level-population-based-prevalence-surveys
#17
Nasiru Muhammad, Caleb Mpyet, Mohammed Dantani Adamu, Adamani William, Murtala Muhammad Umar, Musa Goyol, Habila Muazu, Uwaezuoke Onyebuchi, Sunday Isiyaku, Rebecca M Flueckiger, Brian K Chu, Rebecca Willis, Alexandre L Pavluck, Abdullahi Alhassan, Nicholas Olobio, Bruce A Gordon, Anthony W Solomon
INTRODUCTION: To prepare for global elimination of trachoma by 2020, the World Health Organization (WHO) recommends mapping of trachoma at district-level to enable planning of elimination activities in affected populations. The aim of our study was to provide data on trachoma for each local government area (LGA) of Kaduna State, Nigeria, as such data were previously unavailable. METHOD: As part of the Global Trachoma Mapping Project (GTMP), a population-based cross-sectional trachoma survey was conducted in each of the 23 LGAs of Kaduna State, between May and June 2013...
2016: Ophthalmic Epidemiology
https://www.readbyqxmd.com/read/27918223/prevalence-of-trachoma-in-niger-state-north-central-nigeria-results-of-25-population-based-prevalence-surveys-carried-out-with-the-global-trachoma-mapping-project
#18
Mohammed Dantani Adamu, Caleb Mpyet, Nasiru Muhammad, Murtala Muhammad Umar, Habila Muazu, Francisca Olamiju, Sunday Isiyaku, Uwazoeke Onyebuchi, Usman Abubakar Bosso, Adamani William, Benjamin C Nwobi, Rebecca Willis, Rebecca Mann Flueckiger, Alexandre Pavluck, Brian K Chu, Nicholas Olobio, Anthony W Solomon
PURPOSE: To determine the prevalence of trachoma in each of the 25 local government areas (LGAs) of Niger State, Nigeria. METHODS: A population-based cross-sectional survey was conducted in each Niger State LGA between March and April 2014, as part of the Global Trachoma Mapping Project (GTMP). GTMP protocols were used in planning and conduct of the surveys. Using probability proportional to size, 25 clusters were selected; in each of these clusters, 25 households were enrolled for the survey...
2016: Ophthalmic Epidemiology
https://www.readbyqxmd.com/read/27916485/prevalence-of-gestational-diabetes-among-chinese-and-south-asians-a-canadian-population-based-analysis
#19
Roseanne O Yeung, Anamarie Savu, Brooke Kinniburgh, Lily Lee, Susie Dzakpasu, Chantal Nelson, Jeffrey A Johnson, Lois E Donovan, Edmond A Ryan, Padma Kaul
BACKGROUND: There is considerable geographic variation in gestational diabetes mellitus (GDM) rates. We used data from two Canadian provinces, British Columbia (BC) and Alberta (AB), to determine the impact of ethnicity on GDM prevalence and neonatal outcomes. RESEARCH DESIGN AND METHODS: All deliveries between 04/01/2004 and 03/31/2010 in AB (n=249,796) and BC (n=248,217) were analyzed. We calculated GDM prevalence among Chinese, South-Asian, and the general population (predominantly Caucasian) women...
October 19, 2016: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/27911105/associations-between-maternal-bmi-as-well-as-glucose-tolerance-and-adverse-pregnancy-outcomes-in-women-with-polycystic-ovary-syndrome
#20
Ying-Ying Li, Su-Qi Ye, Zhuo-Hui Zhong, Qiong Xu, Wei-Bi Mai, Cai-Xin Yin, Zhi-Qin Zhu, Xiao-Qian He, Qing Xiao
This retrospective, cohort study examined the association between maternal pre-pregnancy body mass index (BMI), independent of glucose tolerance and adverse pregnancy outcomes in women with polycystic ovary syndrome (PCOS), for which there are few previous studies. Medical records from 2012 to 2015 at Guangzhou Women and Children's Medical Center, China were reviewed for women previously diagnosed with PCOS with normal 2-h 75-g oral glucose tolerance test (OGTT) results (n = 1249). The separate and joint effects of maternal BMI and glucose levels on pregnancy outcomes were assessed...
December 2, 2016: Gynecological Endocrinology
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