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Moro reflex

Elizabeth Allocco, Marjorie Melker, Florencia Rojas-Miguez, Caitlin Bradley, Kristen A Hahn, Elisha M Wachman
BACKGROUND: Twenty percent to 40% of infants exposed to in utero opioid were delivered preterm. There is currently no neonatal abstinence syndrome (NAS) scoring tool known to accurately evaluate preterm opioid-exposed infants. This can lead to difficulties in titrating pharmacotherapy in this population. PURPOSE: To describe NAS symptoms in preterm opioid-exposed infants in comparison with matched full-term controls. METHODS: This was a retrospective cohort study from a single tertiary care center of methadone-exposed infants born between 2006 and 2010...
October 2016: Advances in Neonatal Care: Official Journal of the National Association of Neonatal Nurses
Elisa G Hamer, Mijna Hadders-Algra
The aim of this paper was to systematically review the literature on the significance of specific neurological signs in infancy, in particular in infants at risk for developmental problems such as cerebral palsy (CP). A literature search was performed using the databases PubMed, Embase, Web of Science, and AMED. Papers on infantile reactions ('primitive reflexes') and postural reactions were included if data were available allowing for calculation of sensitivity, specificity, or positive and negative predictive value for CP or atypical developmental outcome...
March 2016: Developmental Medicine and Child Neurology
Zhe Zhang, Valentina Ferretti, İlke Güntan, Alessandro Moro, Eleonora A Steinberg, Zhiwen Ye, Anna Y Zecharia, Xiao Yu, Alexei L Vyssotski, Stephen G Brickley, Raquel Yustos, Zoe E Pillidge, Edward C Harding, William Wisden, Nicholas P Franks
Do sedatives engage natural sleep pathways? It is usually assumed that anesthetic-induced sedation and loss of righting reflex (LORR) arise by influencing the same circuitry to lesser or greater extents. For the α2 adrenergic receptor agonist dexmedetomidine, we found that sedation and LORR were in fact distinct states, requiring different brain areas: the preoptic hypothalamic area and locus coeruleus (LC), respectively. Selective knockdown of α2A adrenergic receptors from the LC abolished dexmedetomidine-induced LORR, but not sedation...
April 2015: Nature Neuroscience
José Alfonso Gutiérrez-Padilla, Horacio Padilla-Muñoz, Hugo Gutiérrez-González, Juan Carlos Barrera-de León, Oscar Miguel Aguirre-Jáuregui, Ricardo Martínez-Verónica, Iván Gutiérrez-González, Luis Manuel Avalos-Huizar
BACKGROUND: Pregnancy in women addicted represents, in itself, a major risk of destruction of physical and mental health of the unborn child; urgent prevention is the same as essential to providing quality care to the mother and child knowledge. OBJECTIVE: Describe the physical and sociodemographic characteristics of neonates in intensive care units, born of mothers with addictions. MATERIALS AND METHOD: Cross-sectional, descriptive study of neonates with addict mothers, analyzing age, gender, clinical symptoms and complications...
July 2014: Ginecología y Obstetricia de México
Shi-Jie Guo, Dong-Xuan Wang, Chun-Lai Dai, Hui Wu
Hand, foot, and mouth disease (HFMD) with serious complications and fatal cases have been reported over the last decade worldwide. The authors report a rare case of HFMD in a neonate complicated with brainstem encephalitis and pulmonary edema. She had fever, lethargy, dyspnea. Physical examination revealed shock signs, fine rales on both lungs, absent Moro reflex. The patient had a rapidly progressive course with seizures, coma, no spontaneous breathing, chemosis. There were some vesicles on left sole and red maculopapular rashes on perianal skin...
July 2014: Pakistan Journal of Medical Sciences Quarterly
S Bijesh, Jyoti Singh, H P Singh
Moro response in healthy term newborns were studied to determine latency interval, time taken for optimal response (embracing movement of arms), and total duration of reflex response. Latency interval for onset of response was 0.41-0.49. Time taken for optimal response was 0.910-1.041s. Total duration of Moro response was 2.34 -2.59 s. Values were similar for males and females. Optimal response in babies born by cesarean section were significantly delayed than vaginal babies.
July 2013: Indian Pediatrics
Akihiro Yugeta, William D Hutchison, Clement Hamani, Utpal Saha, Andres M Lozano, Mojgan Hodaie, Elena Moro, Bogdan Neagu, Robert Chen
Increased oscillations in the beta band are thought to be related to motor symptoms of Parkinson's disease (PD). Previous studies have shown that beta-band desynchronization in the subthalamic nucleus (STN) is reduced just before and during limb movements. While the STN is part of the basal ganglia (BG)-thalamocortical circuit controlling limb movements, it is also part of the BG-brainstem projection controlling saccadic eye movements. Late-stage PD patients have deficits in saccades in addition to difficulties with limb movements arising from impaired functions of the BG...
April 17, 2013: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
Ingrid Brucknerova, Anna Holomanova, Eduard Ujhazy, Mojmir Mach
It is well known that the names of discoverers are commonly used in medical terminology, especially in everyday use. The advantage of an eponym is that a complex description of a certain syndrome, surgical procedure, manifestations of a particular disease, or its details, can be expressed in a single word (Holomáňová & Brucknerová 2003). Current official anatomical nomenclatures do not use eponyms. Some exceptions do however exist. In pediatrics, we frequently use the names of two famous persons: Virginia Apgar and Ernst Moro...
2012: Neuro Endocrinology Letters
Ibone Olza Fernández, Miguel Angel Marín Gabriel, Lourdes García Murillo, Ana María Malalana Martinez, Valeria Costarelli, Isabel Millán Santos
INTRODUCTION: Maternal-infant separation (MIS) is a highly stressful situation for the neonate. MATERIALS AND METHODS: A study was conducted to observe and describe the reactions of term neonates to brief maternal separation and restoration of skin contact within the first 48 h of life, and to assess whether the mode of delivery influences neonatal responsiveness. A brief maternal-infant separation situation was videotaped to observe the reactions of the newborns within the first 12-48 h of life...
May 2013: Early Human Development
Diann E Gaalema, Teresa Linares Scott, Sarah H Heil, Mara G Coyle, Karol Kaltenbach, Gary J Badger, Amelia M Arria, Susan M Stine, Peter R Martin, Hendrée E Jones
AIMS: To compare the profile of signs of neonatal abstinence syndrome (NAS) in methadone- versus buprenorphine-exposed infants. DESIGN, SETTING AND PARTICIPANTS: Secondary analysis of NAS data from a multi-site, double-blind, double-dummy, flexible-dosing, randomized clinical trial. Data from a total of 129 neonates born to opioid-dependent women who had been assigned to receive methadone or buprenorphine treatment during pregnancy were examined. MEASUREMENTS: For 10 days after delivery, neonates (methadone = 72, buprenorphine = 57) were assessed regularly using a 19-item modified Finnegan scale...
November 2012: Addiction
Ali Kanik, Sumer Sutcuoglu, Halil Aydinlioglu, Aydin Erdemir, Esra Arun Ozer
BACKGROUND: The fracture of clavicle is the most frequently observed bone fracture as birth trauma and it is usually unilateral. It is seen following shoulder dystocia deliveries or breech presentation of macrosomic newborns. CASE PRESENTATION: We report two macrosomic newborns with bilateral clavicle fracture and brachial plexus palsy due to birth trauma. Chest X-rays confirmed bilateral fracture of clavicles. Both patients were recovered without any sequel. CONCLUSION: Bilateral clavicular fracture should be considered in any neonate with bilateral absent Moro reflexes...
December 2011: Iranian Journal of Pediatrics
Yasuyuki Futagi, Yasuhisa Toribe, Yasuhiro Suzuki
The plantar grasp reflex is of great clinical significance, especially in terms of the detection of spasticity. The palmar grasp reflex also has diagnostic significance. This grasp reflex of the hands and feet is mediated by a spinal reflex mechanism, which appears to be under the regulatory control of nonprimary motor areas through the spinal interneurons. This reflex in human infants can be regarded as a rudiment of phylogenetic function. The absence of the Moro reflex during the neonatal period and early infancy is highly diagnostic, indicating a variety of compromised conditions...
2012: International Journal of Pediatrics
Fernando Korkes, Paulo Roberto dos Anjos Cabral, Caio Dal Moro Alves, Mariana Lorenzi Savioli, Antonio Carlos Lima Pompeo
PURPOSE: The hypothesis of association between testicular torsion and hyperactive cremasteric reflex, worsened by cold weather, has not been proved. Thirteen studies in the literature evaluated this issue, with inconclusive results. The aim of the present study was to evaluate the seasonality of testicular torsion in a large subset of patients surgically treated in Brazil, and additionally to estimate the incidence of testicular torsion. MATERIALS AND METHODS: Brazilian Public Health System Database was assessed from 1992-2010 to evaluate hospital admissions associated with treatment of testicular torsion...
March 2012: International Braz J Urol: Official Journal of the Brazilian Society of Urology
Min Sohn, Youngmee Ahn, Sangmi Lee
BACKGROUND: Assessment of primitive reflexes is one of the earliest, simplest, and most frequently used assessment tools among health care providers for newborns and young infants. However, very few data exist for high-risk infants in this topic. Among the various primitive reflexes, this study was undertaken particularly to describe the sucking, Babinski and Moro reflexes in high-risk newborns and to explore their relationships with clinical variables. METHODS: This study is a cross-sectional descriptive study...
December 2011: Journal of Clinical Medicine Research
Marianne Berényi, Ferenc Katona, Carmen Sanchez, Mario Mandujano
The group or profile of elementary neuromotor patterns is different from the primitive reflex group which is now called the "primitive reflex profile." All these elementary neuromotor patterns are characterized by a high degree of organization, persistence, and stereotypy. In many regards, these patterns are predecessors or precursors of from them the specific human motor patterns which appear spontaneously later as crawling, creeping, sitting, and walking with erect posture. On the basis of our experiences it can be stated that the elementary neuromotor patterns can be activated in all neonates and young infants as congenital motor functions...
July 30, 2011: Ideggyógyászati Szemle
Peter G J ter Horst, Susanne van der Linde, Jan Pieter Smit, Jan den Boon, Richard A van Lingen, Frank G A Jansman, Lolkje T W De Jong-van den Berg, Bob Wilffert
AIM: After in utero exposure to tricyclic antidepressants, neonatal withdrawal symptoms have been reported with an estimated incidence between 20 and 50%; however, few data are available for clomipramine. This could also be the case for neonatal pharmacokinetic clomipramine parameters and so this study was set up. METHODS: Babies exposed to clomipramine in utero were included in an observational study, approved by the local ethics committee, after written informed consent...
February 2012: British Journal of Clinical Pharmacology
J Termerová, J Janota
The traumatic intracranial haemorrhage still remains a serious complication of instrumental deliveries with an uncertain prognosis. Regarding tentorial haemorrhage, surprisingly few clinical neurological data are available. Most of the references in literature are older case reports, associated frequently with an unfavourable outcome. We report a newborn after a serious tentorial haemorrhage with an excellent neurodevelopmental outcome. Computed tomography (CT) scan of our patient demonstrated an extensive bilateral tentorial haemorrhage extending to the foramen magnum...
2011: Prague Medical Report
Hendrée E Jones, Cheryl Harrow, Kevin E O'Grady, Michael Crocetti, Lauren M Jansson, Karol Kaltenbach
Twenty-nine opioid-exposed and 26 nonopioid-exposed neonates received neonatal abstinence syndrome (NAS) assessment by an examiner blinded to group status twice daily over the first two postnatal days. The opioid-exposed group had higher mean NAS scores than the nonopioid-exposed group. A 3-sign index, consisting of hyperactive moro reflex, mild tremors when undisturbed, and increased muscle tone, showed excellent discrimination between groups. The use of a 3-sign screening index in the days immediately after birth may provide a cost-effective mechanism for the identification of opioid-exposed infants, particularly in infants of women for whom identification of status as a substance user may not be immediately evident...
November 2010: Journal of Opioid Management
Carla Ismirna Santos Alves, Aurea Nogueira de Melo
OBJECTIVE: To describe the maturational development of 20 (aged 32-36 weeks) premature newborns (PNBs) without clinical or neurological complications from birth until term. METHOD: The Saint-Anne Dargassies Scale was applied every two weeks until the age of 37 weeks. RESULTS: The PNBs showed normal Apgar and the growth in head circumference was adequate for postmentrual age. The Friedman ANOVA test found a significant difference only for the heel-to-ear angles from birth until term...
December 2010: Arquivos de Neuro-psiquiatria
Eduardo Toshiyuki Moro, Norma Sueli P Módolo
Pulmonary aspiration of gastric contents, despite its infrequent occurrence, demands special preventive care. Decreased oesophageal sphincter function and protective airway reflexes caused by depression of consciousness, predispose patients to this severe complication. Recently developed preoperative fasting guidelines suggest shorter fasting periods, especially for liquids, providing more comfort to patients and less risk of hypoglycemia and dehydration, without increasing incidence of perioperative pulmonary aspiration...
March 2009: Revista da Associação Médica Brasileira
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