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screening cardiopathies

Eva Giralt-Steinhauer, Elisa Cuadrado-Godia, Carolina Soriano-Tárraga, Ángel Ois, Jordi Jiménez-Conde, Ana Rodríguez-Campello, Alejandra Gómez-González, Elena Muiño-Acuña, Isaac Subirana-Cachinero, Jaume Roquer
INTRODUCTION: The aims of this study are to describe the incidence of paroxysmal atrial fibrillation (pAF) in patients with ischemic stroke (IS) or transient ischemic attack (TIA), and to create a risk prediction model, using immediately available clinical data associated with new pAF diagnosis. METHODS: We analyzed data from the BASICMAR stroke register, with 5 inclusion criteria: (1) diagnosis of IS/TIA; (2) no history of AF or structural cardiopathy; (3) stroke unit (SU) monitoring after normal electrocardiogram in the emergency room; (4) complete etiologic study; and (5) 3-month follow-up...
2015: European Neurology
E Pop, I Popa, D Bolcaş, D Sirca, F Simon, V Costin, V Balaj, T Micle, I H Săvulescu, S Elenes, M Negru, G Cazacu, A Popper, L Gerhardt, E Zavornic, N Anton, I Erdös, H Frăţilă, V Nica, P Mesaroş, P Jozsa, D Lupu, D David, E Derecskey, C Man, E Palfi, H L Vass
Cholesterolemia in a population of 100482 inhabitants of the Bihor district, subjected to screening for the risk factors in ischemic cardiopathy were studied. Together with hyperlipidemias other risk factors were detected: arterial hypertension, obesity, diabetes mellitus, smoking, ischemic alterations of the electrocardiogram, the influence of the noxious agents present at the working place, of the blood groups and disturbances of the menstrual cycle. The mean cholesteremia is of 205 ± 43.7 mgr% (M = 207 ± 43...
October 1981: Revista Medico-chirurgicală̆ a Societă̆ţ̜ii de Medici ş̧i Naturaliş̧ti Din Iaş̧i
Sergio Castorina, Micaela Rapisardi, Salvatore Antoci, Enrico Campanile, Luigia D'Anna, Tiziana Ficili, Rosaria Raciti, Angelo Rocca, Salvo Tolaro, Claudio Salvatore Cinà
A cross-sectional survey was performed among 50 to 75 year-old residents in the town of Regalbuto in Sicily (Italy), to evaluate risk factors and prevalence of cardiovascular diseases (CVD) in this geographically- defined population. Subjects were invited to participate by letter and those accepting to participate were asked to complete a questionnaire collecting personal data and information regarding the presence of risk factors for CVD. All participating subjects aged >50 years and with a minimum of four risk factors for CVD (smoking, hypertension, diabetes, obesity) were screened for cardiac disease and carotid stenosis (> 50% stenosis)...
May 2014: Igiene e Sanità Pubblica
Lobna Ben Mahmoud, Antoine Pariente, Khawla Kammoun, Ahmed Hakim, Hanene Ghozzi, Zouheir Sahnoun, Annie Fourrier, Jamil Hachicha, Khaled Zeghal
OBJECTIVE: To investigate risk factors for acute kidney injury (AKI) in hospitalized patients with chronic kidney disease (CKD) a case-control study was conducted in the Nephrology Department of Hedi Chaker University Hospital in Sfax, Tunisia, for a 1-year period. METHODS: All patients with baseline renal insufficiency hospitalized for AKI were considered as cases. They were compared with control patients with CKD. A conditional logistic regression model was used to identify independent risk factors for AKI in patients with CKD...
February 2014: Clinical Nephrology
Ana Requena-Méndez, Manuel Carlos López, Andrea Angheben, Luis Izquierdo, Isabela Ribeiro, Maria-Jesús Pinazo, Joaquim Gascon, José Muñoz
This article reviews the usefulness of various types of blood-derived biomarkers that are currently being studied to predict the progression of Chagas disease in patients with the indeterminate form, to assess the efficacy of antiparasitic drugs and to identify early cardiac and gastrointestinal damage. The authors used a search strategy based on MEDLINE, Cochrane Library Register for systematic review, EmBase, Global Health and LILACS databases. Out of 1716 screened articles, only 166 articles were eligible for final inclusion...
September 2013: Expert Review of Anti-infective Therapy
B Gasser, F Courtois, S Hojjat-Assari, E A Sauleau, C Buffet, P Brissot
PURPOSE: Hereditary hemochromatosis is characterized by an excessive absorption and progressive accumulation of iron in the liver, the pancreas, the heart, and the joints. Tiredness and joint manifestations occur usually before hepatopathy, diabetes or cardiopathy. Such common and unspecific symptoms seem to be largely unknown and important diagnostic delays have been reported. The aim of this study was to investigate the discovery circumstances and the diagnostic delay. METHODS: A survey was carried out amongst French patients with C282Y homozygous hemochromatosis who were contacted through patients associations or blood centers...
March 2014: La Revue de Médecine Interne
Chiung-Chi Peng, Chiu-Lan Hsieh, Yaw-Bee Ker, Hsi-Yi Wang, Kuan-Chou Chen, Robert Y Peng
SCOPE: The number of patients with chronic kidney disease (CKD) are increasing. Interventions such as controlling hypertension and specific pharmacologic options are recommended. Some nutraceutics may have benefits in this regard. METHODS AND RESULTS: Naringenin (a flavanon), catechin (a flavanol), and quercetin (a flavonol) and rutin (a flavonol rutinoside) were tried on CKD in a Sprague Dawley rat model. Results indicated quercetin to be the most effective therapeutic candidate with respect to renal edema, hypertension, serum creatinine, hematocrit, cardiopathy, aorta calcification, glomerular amyloidosis, erythrocyte depletion in bone marrow, collagen deposition, expressions of TNF-α, cleaved caspase-3, IκBα, PPARα, and serum insulin...
October 2012: Molecular Nutrition & Food Research
Li-Na Feng, Zhi-Ping Bian, Juan Peng, Fang Jiang, Guo-Hai Yang, Ying-Di Zhu, Di Yang, Li-Ping Jiang, Jun-Jie Zhu
A novel multianalyte electrochemical immunoassay was developed for ultrasensitive detection of human cardiopathy biomarkers cardiac troponin I (cTnI) and human heart-type fatty-acid-binding protein (FABP) using metal ion functionalized titanium phosphate nanospheres (TiP-metal ion) as labels. The metal ions could be detected directly through square wave voltammetry (SWV) without metal preconcentration, and the distinct voltammetric peaks had a close relationship with each sandwich-type immunoreaction. The position and size of the peaks reflected the identity and level of the corresponding antigen...
September 18, 2012: Analytical Chemistry
Shamila S Gunatilleke, Claudia M Calvet, Jonathan B Johnston, Chiung-Kuang Chen, Grigori Erenburg, Jiri Gut, Juan C Engel, Kenny K H Ang, Joseph Mulvaney, Steven Chen, Michelle R Arkin, James H McKerrow, Larissa M Podust
BACKGROUND: Chagas Disease, a WHO- and NIH-designated neglected tropical disease, is endemic in Latin America and an emerging infection in North America and Europe as a result of population moves. Although a major cause of morbidity and mortality due to heart failure, as well as inflicting a heavy economic burden in affected regions, Chagas Disease elicits scant notice from the pharmaceutical industry because of adverse economic incentives. The discovery and development of new routes to chemotherapy for Chagas Disease is a clear priority...
2012: PLoS Neglected Tropical Diseases
Karinne Spirandelli Carvalho Naves, Natália Vaz da Trindade, Paulo Pinto Gontijo Filho
INTRODUCTION: Methicillin-resistant Staphylococcus aureus (MRSA) is spread out in hospitals across different regions of the world and is regarded as the major agent of nosocomial infections, causing infections such as skin and soft tissue pneumonia and sepsis. The aim of this study was to identify risk factors for methicillin-resistance in Staphylococcus aureus bloodstream infection (BSI) and the predictive factors for death. METHODS: A retrospective cohort of fifty-one patients presenting bacteraemia due to S...
March 2012: Revista da Sociedade Brasileira de Medicina Tropical
Yves Jackson, Sara Castillo, Perle Hammond, Marius Besson, Anne Brawand-Bron, Diana Urzola, Jean-Michel Gaspoz, François Chappuis
OBJECTIVES: Chronic Chagas disease causes cardiopathy in 20-40% of the 8-10 million people affected. The prevalence of atherogenic factors increases rapidly in Latin America. Somatic, mental, behavioural and social characteristics of the 80,000 Latino migrants with Chagas disease in Europe are not known. We postulate that they may accumulate these factors for poor health--notably cardiovascular-outcomes. METHODS: This study took place at the Geneva University Hospitals in 2011...
May 2012: Tropical Medicine & International Health: TM & IH
Elide Spinelli, Silviana Timpano, Annalisa Fogazzi, Silvia Dester, Susanna Milianti, Rita Padoan
Cystic Fibrosis (CF) is the most frequent recessive disease of Caucasian patients. Association with other diseases or syndromes has previously been reported. Co-morbidity may be a challenge for clinicians, who have to face more severe problems. We have described a CF infant, F508del homozygote, diagnosed by neonatal screening, who also had a chromosome 18q terminal deletion [del (18)(q22-qter)]. Some clinical features of the 18q deletion: e.g., cardiopathy, gastro-oesophageal reflux and severe muscular hypotonia, worsened the CF clinical picture and his quality of life, with repeated pulmonary exacerbations and failure to thrive in the first six months of life...
2011: Italian Journal of Pediatrics
N Calvo, L Mont, B Vidal, M Nadal, S Montserrat, D Andreu, D Tamborero, C Pare, M Azqueta, A Berruezo, J Brugada, M Sitges
AIMS: Transoesophageal echocardiography (TEE) is recommended prior to circumferential pulmonary vein ablation (CPVA) in patients with atrial fibrillation (AF) to identify left atrial (LA) or left atrial appendage (LAA) wall thrombi. It is not clear whether all patients undergoing CPVA should receive pre-procedural TEE. We wanted to assess the incidence of LA thrombus in these patients and to identify factors associated with its presence. METHODS AND RESULTS: Consecutive patients referred for CPVA from 2004 to 2009 underwent TEE within 48 h prior to the procedure...
April 2011: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
C Roux, M Madani, J M Launay, F Rey, D Citadelle, N Mulliez, M Kolf
The development and evolution of PKU can be prevented by prescribing an appropriate diet at an early age. A systematic neonatal screening has been set up in most countries. However, young women suffering from PKU give birth to very severely malformed children (PKU embryopathy: microcephaly, mental retardation, hypotrophy, cardiopathy) unless they again take up the specific diet, until the PHE level has lowered down to normal, before the beginning of gestation. The treatment has to be continued at least during the first months of gestation...
October 1995: Toxicology in Vitro: An International Journal Published in Association with BIBRA
Zilma Silveira Nogueira Reis, Ana Paula Brum Miranda, Cezar de Alencar Lima Rezende, Renan Bragança Detofol, Carolina Ribeiro Costa, Antônio Carlos Vieira Cabral
PURPOSE: to evaluate the importance of maternal plasma concentration of fructosamine as an indicator of fetal congenital cardiopathies in pregnancies complicated by diabetes mellitus. METHODS: this was a retrospective study conducted on 91 pregnant women with diabetes mellitus who underwent routine fetal echocardiography at a university reference center in fetal medicine. Sixty-five patientes who presented pre-gestational diabetes mellitus and plasma fructosamine level were registered in the medical records prior to the ultrasound exam...
February 2010: Revista Brasileira de Ginecologia e Obstetrícia
Bin Wang, Zhi-Jun Chen, Yong Qiu, Wen-Jun Liu
OBJECTIVE: To determine the circulating matrilin-1 levels in adolescent idiopathic scoliosis (AIS), and to investigate its potential role in etiopathogenisis of AIS. METHODS: This study population consisted of 25 patients with AIS from June 2006 to March 2007 and 25 age-matched normal controls. All subjects of the study met the following criteria: no evidence of bone diseases, metabolic diseases or growth disturbances; no evidence of systemic illness or other condition known to affect bone metabolism; and no history of recent steroid intake and surgery of congenital cardiopathy...
November 1, 2009: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
G Kimbally-Kaky, T Gombet, Y Voumbo, S Ikama-Méo, B Elenga-Mbola, A Mbika-Cardorelle, L Dilou, J Ekoba, J L Nkoua, G Moyen, C Bouramoué
The purpose of this study is to screen for rheumatic heart disease as a basis for treatment of the disease and determination of its prevalence in schoolchildren in Brazzaville, Congo. Surveying was conducted in 4 schools located in suburban districts of Brazzaville from May to June 2005. A cohort of 2250 school children was enrolled by random sampling at 3 levels. Age ranged from 5 to 17 years. The variables recorded were age, sex, socioeconomic status, clinical features, and laboratory findings. Clinical selection was based on cardiac auscultation...
December 2008: Médecine Tropicale: Revue du Corps de Santé Colonial
I Durand, N David, G Blaysat, C Marguet
UNLABELLED: Routine prenatal ultrasound screening for the detection of possible cardiopathy has existed in Upper Normandy since 1987, including the continuous training of obstetric ultrasonographers. We evaluated the profitability and the expected benefit of prenatal detection in a nonselected population in this region. METHODS: A retrospective study was undertaken from October 2003 to September 2007 in the cardiopediatric units of Upper Normandy. All fetuses and infants with a diagnosed major cardiac defect were classified into 3 groups: no possibility of anatomic surgical repair (group 1), risk of early decompensation (group 2), and anatomic surgical repair possible but without early decompensation (group 3)...
May 2009: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
Mauro Alberto Ochoa Torres, Ricardo Jorge Hernández Herrera, Jaime Hernández Gerardo, Sergio Arturo Luna García, Yadira Mayela Padilla Martínez
INTRODUCTION: The prevalence of congenital cardiac defects is 8 per 1000 neonates, and it's different if high or low risk populations are studied. The fetal ultrasonographic increase prenatal detection but varies from 7 to 90%. OBJECTIVES: To know the prevalence of fetal cardiopathy and detection in high risk pregnancies. PATIENTS AND METHODS: A observational study was made in pregnancies women with 16 old week of gestation. RESULTS: We received a total of 3500 high-risk pregnancies and were detected 112 cases with fetal cardiopathy (3...
September 2007: Ginecología y Obstetricia de México
José M Soler Picart, Joan Martínez Benazet, Noemí Cerdán Riart
BACKGROUND AND OBJECTIVE: Several studies have described the changes observed in the response of the autonomous nervous system in patients with obstructive sleep apnea syndrome (OSAS). From the point of view of cardiology outpatients, we tried to relate the presence of the disease with the behavior of a Holter algorithm, the very low frequency increment (VLFI), in a direct relationship to sympathetic regulation during sleep. In addition, we studied the characteristics of our population group with regard to OSAS...
October 13, 2007: Medicina Clínica
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