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https://www.readbyqxmd.com/read/28214580/localization-of-oxytocin-receptors-in-the-prairie-vole-microtus-ochrogaster-neocortex
#1
Auriane Duchemin, Adele M H Seelke, Trenton C Simmons, Sara M Freeman, Karen L Bales
Early experience and social context interact to alter the phenotype of complex social behaviors. These early experiences can also result in alterations to cortical organization and connections. Given the ability of the neuropeptide oxytocin (OT) to modulate social and reproductive behavior, OT is likely involved in these cortical processes. However, little is known about the distribution of OT and OT receptors (OTR) within the neocortex. Using autoradiographic and neuroanatomical techniques, we characterized the cortical distribution of oxytocin receptors (OTR) in prairie voles, a socially monogamous rodent species...
February 15, 2017: Neuroscience
https://www.readbyqxmd.com/read/28213292/improving-therapeutic-outcomes-in-autism-spectrum-disorders-enhancing-social-communication-and-sensory-processing-through-the-use-of-interactive-robots
#2
REVIEW
Felippe Sartorato, Leon Przybylowski, Diana K Sarko
For children with autism spectrum disorders (ASDs), social robots are increasingly utilized as therapeutic tools in order to enhance social skills and communication. Robots have been shown to generate a number of social and behavioral benefits in children with ASD including heightened engagement, increased attention, and decreased social anxiety. Although social robots appear to be effective social reinforcement tools in assistive therapies, the perceptual mechanism underlying these benefits remains unknown...
February 7, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/28213038/hydrolysate-from-a-mixture-of-legume-flours-with-antifungal-activity-as-an-ingredient-for-prolonging-the-shelf-life-of-wheat-bread
#3
Carlo Giuseppe Rizzello, Michela Verni, Stefano Bordignon, Valerio Gramaglia, Marco Gobbetti
Aiming at identifying antifungal compounds from plant matrices to be used as ingredients in the bakery industry, a water/salt-soluble extract (WSE) was produced from a legume enzyme hydrolysate, consisting of a mixture of pea, lentil, and faba bean flours, and assayed towards Penicillium roqueforti DPPMAF1. Agar diffusion assays allowed the selection of the optimal processing conditions for hydrolysis. As shown by hyphal radial growth rate, the inhibition was observed towards several fungi, including Aspergillus parasiticus CBS971...
June 2017: Food Microbiology
https://www.readbyqxmd.com/read/28211587/histaminergic-and-non-histaminergic-elicited-itch-is-attenuated-in-capsaicin-evoked-areas-of-allodynia-and-hyperalgesia-a-healthy-volunteer-study
#4
H H Andersen, J Elberling, N Sharma, L E Hauberg, P Gazerani, L Arendt-Nielsen
BACKGROUND: Chronic pain patients with sensitization may exhibit decreased sensitivity to normally pruritogenic sensory stimuli and moreover occasionally perceive these as painful. This study explored the relationship between itch and pain, by evaluating histaminergic and non-histaminergic itch evoked in capsaicin-induced allodynic and hyperalgesic areas. METHODS: In 28 healthy volunteers, capsaicin (100 μg/0.1 mL) was injected intradermally in the volar forearm to establish secondary dysesthesias...
February 17, 2017: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/28210712/identification-of-an-epidermal-keratinocyte-ampa-glutamate-receptor-involved-in-dermatopathies-associated-with-sensory-abnormalities
#5
David Cabañero, Takeshi Irie, Marta Celorrio, Christopher Trousdale, David M Owens, David Virley, Phillip J Albrecht, Michael J Caterina, Frank L Rice, Jose A Morón
INTRODUCTION: Epidermal keratinocytes are increasingly recognized as active participants in the sensory transduction of itch and pain, processes known to involve primary afferent glutamatergic neurons. However the role of keratinocyte glutamate signaling in sensory functioning is not fully understood. Here, we present the observation of α-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid type glutamate receptors (AMPAR) in epidermal keratinocytes. METHODS: Immunohistochemical and in situ hybridization analyses were conducted to assess the expression of AMPAR subunits in epidermal keratinocytes in mouse and human skin samples, and in organotypic cultures of human keratinocytes...
September 2016: Pain Reports (Baltimore, Md.)
https://www.readbyqxmd.com/read/28210486/touch-accelerates-visual-awareness
#6
Claudia Lunghi, Luca Lo Verde, David Alais
To efficiently interact with the external environment, our nervous system combines information arising from different sensory modalities. Recent evidence suggests that cross-modal interactions can be automatic and even unconscious, reflecting the ecological relevance of cross-modal processing. Here, we use continuous flash suppression (CFS) to directly investigate whether haptic signals can interact with visual signals outside of visual awareness. We measured suppression durations of visual gratings rendered invisible by CFS either during visual stimulation alone or during visuo-haptic stimulation...
January 2017: I-Perception
https://www.readbyqxmd.com/read/28210219/mice-lacking-m1-and-m3-muscarinic-acetylcholine-receptors-have-impaired-odor-discrimination-and-learning
#7
Wilson Chan, Sanmeet Singh, Taj Keshav, Ramita Dewan, Christian Eberly, Robert Maurer, Alexia Nunez-Parra, Ricardo C Araneda
The cholinergic system has extensive projections to the olfactory bulb (OB) where it produces a state-dependent regulation of sensory gating. Previous work has shown a prominent role of muscarinic acetylcholine (ACh) receptors (mAChRs) in regulating the excitability of OB neurons, in particular the M1 receptor. Here, we examined the contribution of M1 and M3 mAChR subtypes to olfactory processing using mice with a genetic deletion of these receptors, the M1(-/-) and the M1/M3(-/-) knockout (KO) mice. Genetic ablation of the M1 and M3 mAChRs resulted in a significant deficit in odor discrimination of closely related molecules, including stereoisomers...
2017: Frontiers in Synaptic Neuroscience
https://www.readbyqxmd.com/read/28209761/genetic-adaptation-of-the-schizothoracine-fishes-to-the-phased-uplifting-of-qinghai-tibetan-plateau
#8
Dongsheng Zhang, Mengchao Yu, Peng Hu, Sihua Peng, Yimeng Liu, Weiwen Li, Congcong Wang, Shunping He, Wanying Zhai, Qianghua Xu, Liangbiao Chen
Many species of Schizothoracine, a sub-family of Cyprinidae, are highly endemic to the Qinghai-Tibetan Plateau (QTP). To characterize the adaptive changes associated with the Schizothoracine expansion in high-altitudes, we sequenced tissue transcriptomes of two highland and two sub-highland Schizothoracines, and analyzed gene evolution patterns by comparing to lowland cyprinids. Phylogenetic tree reconstruction and divergence time estimation indicated that the common ancestor of Schizothoracine fishes lived around 32...
February 16, 2017: G3: Genes—Genomes—Genetics
https://www.readbyqxmd.com/read/28209390/liquid-crystal-based-capillary-sensory-platform-for-the-detection-of-bile-acids
#9
Hyeong Jin Kim, Chang-Hyun Jang
Bile acids directly related to liver and intestinal function are used as indicators of hepatobiliary and intestinal diseases. Here, we have designed and realized a capillary sensory platform for the detection of bile acids using liquid crystals (LCs). LC droplets confined in micro-capillaries are homeotropically aligned at the surfactant-packed LC/aqueous interface. However, the competitive adsorption of bile acids disrupts the surfactant packing at this interface and triggers the orientational transition of the LC droplets from homeotropic to planar at the interface, followed by changes in optical images captured by polarized light microscopy...
February 13, 2017: Chemistry and Physics of Lipids
https://www.readbyqxmd.com/read/28207786/hearing-flashes-and-seeing-beeps-timing-audiovisual-events
#10
Manuel Vidal
Many events from daily life are audiovisual (AV). Handclaps produce both visual and acoustic signals that are transmitted in air and processed by our sensory systems at different speeds, reaching the brain multisensory integration areas at different moments. Signals must somehow be associated in time to correctly perceive synchrony. This project aims at quantifying the mutual temporal attraction between senses and characterizing the different interaction modes depending on the offset. In every trial participants saw four beep-flash pairs regularly spaced in time, followed after a variable delay by a fifth event in the test modality (auditory or visual)...
2017: PloS One
https://www.readbyqxmd.com/read/28205639/biological-motion-distorts-size-perception
#11
Peter Veto, Wolfgang Einhäuser, Nikolaus F Troje
Visual illusions explore the limits of sensory processing and provide an ideal testbed to study perception. Size illusions - stimuli whose size is consistently misperceived - do not only result from sensory cues, but can also be induced by cognitive factors, such as social status. Here we investigate, whether the ecological relevance of biological motion can also distort perceived size. We asked observers to judge the size of point-light walkers (PLWs), configurations of dots whose movements induce the perception of human movement, and visually matched control stimuli (inverted PLWs)...
February 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28205499/motor-adaptation-deficits-in-ideomotor-apraxia
#12
Pratik K Mutha, Lee H Stapp, Robert L Sainburg, Kathleen Y Haaland
OBJECTIVES: The cardinal motor deficits seen in ideomotor limb apraxia are thought to arise from damage to internal representations for actions developed through learning and experience. However, whether apraxic patients learn to develop new representations with training is not well understood. We studied the capacity of apraxic patients for motor adaptation, a process associated with the development of a new internal representation of the relationship between movements and their sensory effects...
February 2017: Journal of the International Neuropsychological Society: JINS
https://www.readbyqxmd.com/read/28204865/prediction-of-human-sensory-irritation-due-to-ethyl-acrylate-the-appropriateness-of-time-weighted-average-concentration%C3%A2-%C3%A3-%C3%A2-time-models-for-varying-concentrations
#13
Stefan Kleinbeck, Michael Schäper, Anna Zimmermann, Meinolf Blaszkewicz, Thomas Brüning, Christoph van Thriel
Human data about the potency of ethyl acrylate to evoke sensory irritation is currently not available. Therefore, we conducted an experimental exposure study and the magnitude of chemosensory effects in healthy human volunteers was mathematically modeled by combining the factors current concentration (c) and duration/time (t). In a repeated-measures design, 19 subjects were exposed for 4 h to constant and varying concentrations (including peaks of 5 and 10 ppm) of ethyl acrylate with either a 2.5 or 5 ppm time-weighted average (TWA) concentration...
February 15, 2017: Archives of Toxicology
https://www.readbyqxmd.com/read/28203388/on-the-development-of-the-chondrocranium-and-the-histological-anatomy-of-the-head-in-perinatal-stages-of-marsupial-mammals
#14
REVIEW
Marcelo R Sánchez-Villagra, Analía M Forasiepi
An overview of the literature on the chondrocranium of marsupial mammals reveals a relative conservatism in shape and structures. We document the histological cranial anatomy of individuals representing Monodelphis domestica, Dromiciops gliroides, Perameles sp. and Macropus eugenii. The marsupial chondrocranium is generally characterized by the great breadth of the lamina basalis, absence of pila metoptica and large otic capsules. Its most anterior portion (cupula nasi anterior) is robust, and anterior to it there are well-developed tactile sensory structures, functionally important in the neonate...
2017: Zoological Letters
https://www.readbyqxmd.com/read/28203353/auditory-stimulus-detection-partially-depends-on-visuospatial-attentional-resources
#15
Basil Wahn, Supriya Murali, Scott Sinnett, Peter König
Humans' ability to detect relevant sensory information while being engaged in a demanding task is crucial in daily life. Yet, limited attentional resources restrict information processing. To date, it is still debated whether there are distinct pools of attentional resources for each sensory modality and to what extent the process of multisensory integration is dependent on attentional resources. We addressed these two questions using a dual task paradigm. Specifically, participants performed a multiple object tracking task and a detection task either separately or simultaneously...
January 2017: I-Perception
https://www.readbyqxmd.com/read/28203334/assessment-of-sexual-maturation-among-girls-with-special-needs-in-tehran-iran
#16
Hosein Shabani Mirzaee, Asieh Mosallanejad, Ali Rabbani, Aria Setoodeh, Farzaneh Abbasi, Fatemeh Sayarifard, Amir Hosein Memari
BACKGROUND: There is limited data on sexual maturation among girls with intellectual, sensory, or physical disabilities. OBJECTIVES: The present cross-sectional study was conducted to assess the sexual maturation of girls with these disabilities in special schools. METHODS: In this cross-sectional study, we evaluated the onset and progression of sexual maturation in 642 six to 18-year-old girls with intellectual, sensory, or physical disabilities from special schools in Tehran...
October 2016: Iranian Journal of Pediatrics
https://www.readbyqxmd.com/read/28203219/toward-a-dynamic-probabilistic-model-for-vestibular-cognition
#17
Andrew W Ellis, Fred W Mast
We suggest that research in vestibular cognition will benefit from the theoretical framework of probabilistic models. This will aid in developing an understanding of how interactions between high-level cognition and low-level sensory processing might occur. Many such interactions have been shown experimentally; however, to date, no attempt has been made to systematically explore vestibular cognition by using computational modeling. It is widely assumed that mental imagery and perception share at least in part neural circuitry, and it has been proposed that mental simulation is closely connected to the brain's ability to make predictions...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28202254/robust-interactions-between-the-effects-of-auditory-and-cutaneous-electrical-stimulations-on-cell-activities-in-the-thalamic-reticular-nucleus
#18
Akihisa Kimura
The thalamic reticular nucleus (TRN), a cluster of GABAergic cells, is thought to regulate bottom-up and top-down streams of sensory processing in the loop circuitry between the thalamus and cortex. Provided that sensory inputs of different modalities interact in the TRN, the TRN could contribute to fast and flexible cross-modal modulation of attention and perception that incessantly takes place in our every day life. Indeed, diverse subthreshold interactions of auditory and visual inputs have been revealed in TRN cells (Kimura, 2014)...
February 12, 2017: Brain Research
https://www.readbyqxmd.com/read/28197789/surgical-outcome-for-severe-cubital-tunnel-syndrome-in-patients-aged-70%C3%A2-years-a-mean-follow-up-of-4-5%C3%A2-years
#19
Jinsong Tong, Bin Xu, Zhen Dong, Chenggang Zhang, Yudong Gu
BACKGROUND: Surgical outcomes for cubital tunnel syndrome have been reported to be satisfactory, but could be compromised by advanced age and severe nerve compression. We aim to evaluate the prognosis of severe cubital tunnel syndrome in patients aged >70 years. METHODS: This retrospective study included 25 patients (26 extremities, all McGowan grade III, age >70 years); 21 underwent subcutaneous transposition and 5 in situ decompression. Postoperative follow-up lasted >2 years...
February 14, 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/28197674/role-of-vision-in-sighted-and-blind-soccer-players-in-adapting-to-an-unstable-balance-task
#20
María Campayo-Piernas, Carla Caballero, David Barbado, Raúl Reina
This study tested whether a compensatory hypothesis exists on postural control during standing unstable balance tasks comparing blind soccer players (n = 7) to sighted soccer players (n = 15) and sighted sedentary individuals (n = 6). All subjects performed a pre-test, a training of ten practice trials on a single day, and a post-test balance test. All tests were performed on an unstable surface placed on a force platform and under closed-eyes conditions, and a final test was performed with open eyes...
February 14, 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
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