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https://www.readbyqxmd.com/read/29686878/limitation-of-life-support-techniques-at-admission-to-the-intensive-care-unit-a-multicenter-prospective-cohort-study
#1
Olga Rubio, Anna Arnau, Sílvia Cano, Carles Subirà, Begoña Balerdi, María Eugenía Perea, Miguel Fernández-Vivas, María Barber, Noemí Llamas, Susana Altaba, Ana Prieto, Vicente Gómez, Mar Martin, Marta Paz, Belen Quesada, Valentí Español, Juan Carlos Montejo, José Manuel Gomez, Gloria Miro, Judith Xirgú, Ana Ortega, Pedro Rascado, Juan María Sánchez, Alfredo Marcos, Ana Tizon, Pablo Monedero, Elisabeth Zabala, Cristina Murcia, Ines Torrejon, Kenneth Planas, José Manuel Añon, Gonzalo Hernandez, María-Del-Mar Fernandez, Consuelo Guía, Vanesa Arauzo, José Miguel Perez, Rosa Catalan, Javier Gonzalez, Rosa Poyo, Roser Tomas, Iñaki Saralegui, Jordi Mancebo, Charles Sprung, Rafael Fernández
Purpose: To determine the frequency of limitations on life support techniques (LLSTs) on admission to intensive care units (ICU), factors associated, and 30-day survival in patients with LLST on ICU admission. Methods: This prospective observational study included all patients admitted to 39 ICUs in a 45-day period in 2011. We recorded hospitals' characteristics (availability of intermediate care units, usual availability of ICU beds, and financial model) and patients' characteristics (demographics, reason for admission, functional status, risk of death, and LLST on ICU admission (withholding/withdrawing; specific techniques affected))...
2018: Journal of Intensive Care
https://www.readbyqxmd.com/read/29660816/bacterial-communities-in-serpa-cheese-by-culture-dependent-techniques-16s-rrna-gene-sequencing-and-high-throughput-sequencing-analysis
#2
Maria Teresa P Gonçalves, María José Benito, María de Guía Córdoba, Conceição Egas, Almudena V Merchán, Ana I Galván, Santiago Ruiz-Moyano
Serpa cheese is one of the traditional regional Portuguese cheeses having the Protected Denomination of Origin (PDO) designation. This study investigated the bacterial community in the traditional Portuguese Serpa cheese. The microorganisms identified at the end of ripening (30 days) mainly were lactic acid bacteria (LAB). Lactobacillus paracasei/Lactobacillus casei was the main species in cheese from PDO registered industries, whereas in non-PDO registered industries Lactobacillus brevis was highlighted, among other LAB...
April 16, 2018: Journal of Food Science
https://www.readbyqxmd.com/read/29604157/the-response-of-soil-solution-chemistry-in-european-forests-to-decreasing-acid-deposition
#3
James Johnson, Elisabeth Graf Pannatier, Stefano Carnicelli, Guia Cecchini, Nicholas Clarke, Nathalie Cools, Karin Hansen, Henning Meesenburg, Tiina M Nieminen, Gunilla Pihl Karlsson, Hugues Titeux, Elena Vanguelova, Arne Verstraeten, Lars Vesterdal, Peter Waldner, Mathieu Jonard
Acid deposition arising from sulphur (S) and nitrogen (N) emissions from fossil fuel combustion and agriculture has contributed to the acidification of terrestrial ecosystems in many regions globally. However, in Europe and North America, S deposition has greatly decreased in recent decades due to emissions controls. In this study we assessed the response of soil solution chemistry in mineral horizons of European forests to these changes. Trends in pH, acid neutralising capacity (ANC), major ions, total aluminium (Altot ), and dissolved organic carbon (DOC) were determined for the period 1995-2012...
March 31, 2018: Global Change Biology
https://www.readbyqxmd.com/read/29559087/noncoding-rnas-stress-glucocorticoids-and-posttraumatic-stress-disorder
#4
REVIEW
Nikolaos P Daskalakis, Allison C Provost, Richard G Hunter, Guia Guffanti
Posttraumatic stress disorder (PTSD) is a pathologic response to trauma that impacts ∼8% of the population and is highly comorbid with other disorders, such as traumatic brain injury. PTSD affects multiple biological systems throughout the body, including the hypothalamic-pituitary-adrenal axis, cortical function, and the immune system, and while the study of the biological underpinnings of PTSD and related disorders are numerous, the roles of noncoding RNAs (ncRNAs) are just emerging. Moreover, deep sequencing has revealed that ncRNAs represent most of the transcribed mammalian genome...
January 31, 2018: Biological Psychiatry
https://www.readbyqxmd.com/read/29533167/systematic-transcreation-of-self-help-smoking-cessation-materials-for-hispanic-latino-smokers-improving-cultural-relevance-and-acceptability
#5
Bárbara Piñeiro, Diana R Díaz, Luis M Monsalve, Úrsula Martínez, Cathy D Meade, Lauren R Meltzer, Karen O Brandon, Marina Unrod, Thomas H Brandon, Vani N Simmons
Smoking-related illnesses are the leading causes of death among Hispanics/Latinos. Yet, there are few smoking cessation interventions targeted for this population. The goal of this study was to "transcreate" an existing, previously validated, English language self-help smoking cessation intervention, titled Forever Free® : Stop Smoking for Good, for Spanish-speaking smokers. Rather than simply translating the materials, our transcreation process involved culturally adapting the intervention to enhance acceptability and receptivity of the information...
2018: Journal of Health Communication
https://www.readbyqxmd.com/read/29427798/evidence-for-multiple-sylvatic-transmission-cycles-during-the-2016-2017-yellow-fever-virus-outbreak-brazil
#6
A Moreira-Soto, M C Torres, M C Lima de Mendonça, M A Mares-Guia, C D Dos Santos Rodrigues, A A Fabri, C C Dos Santos, E S Machado Araújo, C Fischer, R M Ribeiro Nogueira, C Drosten, P Carvalho Sequeira, J F Drexler, A M Bispo de Filippis
OBJECTIVES: Since December 2016, Brazil has experienced an unusually large outbreak of yellow fever (YF). Whether urban transmission may contribute to the extent of the outbreak is unclear. The objective of this study was to characterize YF virus (YFV) genomes and to identify spatial patterns to determine the distribution and origin of YF cases in Minas Gerais, Espírito Santo and Rio de Janeiro, the most affected Brazilian states during the current YFV outbreak. METHODS: We characterized near-complete YFV genomes from 14 human cases and two nonhuman primates (NHP), sampled from February to April 2017, retrieved epidemiologic data of cases and used a geographic information system to investigate the geospatial spread of YFV...
February 7, 2018: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/29164935/hispanic-health-care-international-gu%C3%A3-a-de-autores
#7
(no author information available yet)
No abstract text is available yet for this article.
September 2017: Hispanic Health Care International: the Official Journal of the National Association of Hispanic Nurses
https://www.readbyqxmd.com/read/29141897/effects-of-health-and-social-care-spending-constraints-on-mortality-in-england-a-time-trend-analysis
#8
Johnathan Watkins, Wahyu Wulaningsih, Charlie Da Zhou, Dominic C Marshall, Guia D C Sylianteng, Phyllis G Dela Rosa, Viveka A Miguel, Rosalind Raine, Lawrence P King, Mahiben Maruthappu
OBJECTIVE: Since 2010, England has experienced relative constraints in public expenditure on healthcare (PEH) and social care (PES). We sought to determine whether these constraints have affected mortality rates. METHODS: We collected data on health and social care resources and finances for England from 2001 to 2014. Time trend analyses were conducted to compare the actual mortality rates in 2011-2014 with the counterfactual rates expected based on trends before spending constraints...
November 15, 2017: BMJ Open
https://www.readbyqxmd.com/read/29141867/host-resistance-to-endotoxic-shock-requires-the-neuroendocrine-regulation-of-group-1-innate-lymphoid-cells
#9
Linda Quatrini, Elisabeth Wieduwild, Sophie Guia, Claire Bernat, Nicolas Glaichenhaus, Eric Vivier, Sophie Ugolini
Upon infection, the immune system produces inflammatory mediators important for pathogen clearance. However, inflammation can also have deleterious effect on the host and is tightly regulated. Immune system-derived cytokines stimulate the hypothalamic-pituitary-adrenal (HPA) axis, triggering endogenous glucocorticoid production. Through interaction with ubiquitously expressed glucocorticoid receptors (GRs), this steroid hormone has pleiotropic effects on many cell types. Using a genetic mouse model in which the gene encoding the GR is selectively deleted in NKp46+ innate lymphoid cells (ILCs), we demonstrated a major role for the HPA pathway in host resistance to endotoxin-induced septic shock...
December 4, 2017: Journal of Experimental Medicine
https://www.readbyqxmd.com/read/29135974/early-meteorological-records-from-latin-america-and-the-caribbean-during-the-18th-and-19th-centuries
#10
Fernando Domínguez-Castro, José Manuel Vaquero, María Cruz Gallego, Ana María Marín Farrona, Juan Carlos Antuña-Marrero, Erika Elizabeth Cevallos, Ricardo García Herrera, Cristina de la Guía, Raúl David Mejía, José Manuel Naranjo, María Del Rosario Prieto, Luis Enrique Ramos Guadalupe, Lizardo Seiner, Ricardo Machado Trigo, Marcos Villacís
This paper provides early instrumental data recovered for 20 countries of Latin-America and the Caribbean (Argentina, Bahamas, Belize, Brazil, British Guiana, Chile, Colombia, Costa Rica, Cuba, Ecuador, France (Martinique and Guadalupe), Guatemala, Jamaica, Mexico, Nicaragua, Panama, Peru, Puerto Rico, El Salvador and Suriname) during the 18th and 19th centuries. The main meteorological variables retrieved were air temperature, atmospheric pressure, and precipitation, but other variables, such as humidity, wind direction, and state of the sky were retrieved when possible...
November 14, 2017: Scientific Data
https://www.readbyqxmd.com/read/29078153/comorbidity-classes-and-associated-impairment-demographics-and-9-11-exposures-in-8-236-children-and-adolescents
#11
Lupo Geronazzo-Alman, Guia Guffanti, Ruth Eisenberg, Bin Fan, George J Musa, Judith Wicks, Michaeline Bresnahan, Cristiane S Duarte, Christina Hoven
The extensive comorbidity of psychiatric disorders in children and adolescents leads to clinical heterogeneity, and is an often-overlooked issue in etiopathogenic and treatment studies in developmental psychopathology. In a representative sample (N=8236) of New York City public school students assessed six months after 9/11, latent class analysis was applied to 48 symptoms across seven disorders: posttraumatic stress, agoraphobia, separation anxiety, panic disorder, generalized anxiety (GAD), major depression (MDD) and conduct disorder (CD)...
October 16, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/29069725/notch4-and-mhc-class-ii-polymorphisms-are-associated-with-hcv-related-benign-and-malignant-lymphoproliferative-diseases
#12
Laura Gragnani, Elisa Fognani, Valli De Re, Massimo Libra, Adriana Garozzo, Patrizio Caini, Guia Cerretelli, Andrea Giovannelli, Serena Lorini, Monica Monti, Silvia Bagnoli, Irene Piaceri, Anna Linda Zignego
Mixed cryoglobulinemia (MC), is a HCV-related, clinically benign, lymphoproliferative disorder (LPD) that may evolve into a non Hodgkin's lymphoma (NHL). Significant associations were found between two single nucleotide polymorphisms near NOTCH4 (rs2071286) and the HLA class II (rs9461776) genes and HCV-related MC syndrome (MCS). We analyzed NOTCH4 rs2071286 and HLA-II rs9461776 in 3 HCV-related LPD groups (asymptomatic MC, MCS, NHL) with HCV infection without lymphoproliferative disorders. We found a positive relationship between NOTCH4 rs207186 T minor allele frequency (MAF) and patients with HCV-related LPDs at risk of NHL (Chi-square test for trend = 14...
September 22, 2017: Oncotarget
https://www.readbyqxmd.com/read/29036849/newly-developed-learning-and-verbal-memory-test-tamv-i-normative-data-for-spanish-speaking-pediatric-population
#13
D Rivera, L Olabarrieta-Landa, B V Rabago Barajas, M J Irías Escher, M Saracostti Schwartzman, R Ferrer-Cascales, P Martín-Lobo, J A Calderón, M A Aguilar Uriarte, A I Peñalver Guia, R Camlla Ynga, C E García-Guerrero, I Fernandez-Agis, A García-Gómez-Pastrana, J A Ibañéz-Alfonso, H Gómez, J Galarza-Del-Angel, C García de la Cadena, J C Arango-Lasprilla
OBJECTIVE: To generate normative data for the Learning and Verbal Memory Test (TAMV-I) in Spanish-speaking pediatric populations. METHOD: The sample consisted of 4,373 healthy children from nine countries in Latin America (Chile, Cuba, Ecuador, Guatemala, Honduras, Mexico, Paraguay, Peru, and Puerto Rico) and Spain. Each participant was administered the TAMV-I as part of a larger neuropsychological battery. Free recall, memory delay and recognition scores were normed using multiple linear regressions and standard deviations of residual values...
2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/29034010/developing-a-framework-of-gastronomic-systems-research-to-unravel-drivers-of-food-choice
#14
Rosa Paula Cuevas, Annalyn de Guia, Matty Demont
Nutritional and dietary interventions and the introduction of novel food products and ingredients require a thorough understanding of the drivers of food choice, which are embedded in local context and culture. We developed a framework of "gastronomic systems research" (GSR) to understand culture-specific consumer food choice, and contextualise it to a target population of urban, middle- to high-income Filipino consumers to assess the domestic niche market potential of traditional rice varieties in the Philippines...
October 2017: International Journal of Gastronomy and Food Science
https://www.readbyqxmd.com/read/29025687/serine-racemase-and-d-serine-in-the-amygdala-are-dynamically-involved-in-fear-learning
#15
Darrick T Balu, Kendall Taylor Presti, Cathy C Y Huang, Kevin Muszynski, Inna Radzishevsky, Herman Wolosker, Guia Guffanti, Kerry J Ressler, Joseph T Coyle
BACKGROUND: The amygdala is a central component of the neural circuitry that underlies fear learning. N-methyl-D-aspartate receptor-dependent plasticity in the amygdala is required for pavlovian fear conditioning and extinction. N-methyl-D-aspartate receptor activation requires the binding of a coagonist, D-serine, which is synthesized from L-serine by the neuronal enzyme serine racemase (SR). However, little is known about SR and D-serine function in the amygdala. METHODS: We used immunohistochemical methods to characterize the cellular localization of SR and D-serine in the mouse and human amygdala...
February 1, 2018: Biological Psychiatry
https://www.readbyqxmd.com/read/28977232/humanization-in-the-intensive-care-perception-of-family-and-healthcare-professionals
#16
Flavia Feron Luiz, Rita Catalina Aquino Caregnato, Márcia Rosa da Costa
Objective: Understanding perceptions of family members and healthcare professionals about humanization at the Intensive Care Unit (ICU) to direct it to an educational action. Method: Exploratory descriptive and qualitative study conducted in an ICU level 3 of a public hospital in Porto Alegre, RS, Brazil, with fourteen subjects, eight family members and six healthcare professionals. Data collection carried out through semi-structured interviews and focus group. Content Analysis was used...
September 2017: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/28964999/yeast-community-in-traditional-portuguese-serpa-cheese-by-culture-dependent-and-independent-dna-approaches
#17
Maria Teresa P Gonçalves Dos Santos, María José Benito, María de Guía Córdoba, Nuno Alvarenga, Santiago Ruiz-Moyano Seco de Herrera
This study investigated the yeast community present in the traditional Portuguese cheese, Serpa, by culture-dependent and -independent methods. Sixteen batches of Serpa cheeses from various regional industries registered with the Protected Designation of Origin (PDO) versus non-PDO registered, during spring and winter, were used. Irrespective of the producer, the yeast counts were around 5log CFU/g in winter and, overall, were lower in spring. The yeast species identified at the end of ripening (30days), using PCR-RFLP analysis and sequencing of the 26S rRNA, mainly corresponded to Debaryomyces hansenii and Kluyveromyces marxianus, with Candida spp...
December 4, 2017: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/28964236/the-pre-launch-characterization-of-simbio-sys-vihi-imaging-spectrometer-for-the-bepicolombo-mission-to-mercury-i-linearity-radiometry-and-geometry-calibrations
#18
Gianrico Filacchione, Fabrizio Capaccioni, Francesca Altieri, Cristian Carli, Iacopo Ficai Veltroni, Michele Dami, Leonardo Tommasi, Gianluca Aroldi, Donato Borrelli, Alessandra Barbis, Marco Baroni, Guia Pastorini, Raffaele Mugnuolo
Before integration aboard European Space Agency BepiColombo mission to Mercury, the visible and near infrared hyperspectral imager underwent an intensive calibration campaign. We report in Paper I about the radiometric and linearity responses of the instrument including the optical setups used to perform them. Paper II [F. Altieri et al., Rev. Sci. Instrum. 88, 094503 (2017)] will describe complementary spectral response calibration. The responsivity is used to calculate the expected instrumental signal-to-noise ratio for typical observation scenarios of the BepiColombo mission around Mercury...
September 2017: Review of Scientific Instruments
https://www.readbyqxmd.com/read/28961425/fkbp5-dna-methylation-does-not-mediate-the-association-between-childhood-maltreatment-and-depression-symptom-severity-in-the-detroit-neighborhood-health-study
#19
Angela C Bustamante, Allison E Aiello, Guia Guffanti, Sandro Galea, Derek E Wildman, Monica Uddin
Exposure to childhood maltreatment increases the risk of developing mental illness later in life. Childhood maltreatment and depression have both been associated with dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis-a key regulator of the body's stress response. Additionally, HPA axis dysregulation has been implicated in the etiology of a range of mental illnesses. A substantial body of work has shown history of childhood maltreatment alters DNA methylation levels within key HPA axis genes. We therefore investigated whether one of these key genes, FKBP5 mediates the relationship between childhood maltreatment and depression, and assessed FKBP5 DNA methylation and gene expression within 112 adults from the Detroit Neighborhood Health Study (DNHS)...
January 2018: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/28946595/stroop-color-word-interference-test-normative-data-for-spanish-speaking-pediatric-population
#20
D Rivera, A Morlett-Paredes, A I Peñalver Guia, M J Irías Escher, M Soto-Añari, A Aguayo Arelis, S Rute-Pérez, A Rodriguez-Lorenzana, Y Rodríguez-Agudelo, N Albaladejo-Blázquez, C García de la Cadena, J A Ibáñez-Alfonso, W Rodriguez-Irizarry, C E García-Guerrero, I D Delgado-Mejía, A Padilla-López, E Vergara-Moragues, M D Barrios Nevado, M Saracostti Schwartzman, J C Arango-Lasprilla
OBJECTIVE: To generate normative data for the Stroop Word-Color Interference test in Spanish-speaking pediatric populations. METHOD: The sample consisted of 4,373 healthy children from nine countries in Latin America (Chile, Cuba, Ecuador, Guatemala, Honduras, Mexico, Paraguay, Peru, and Puerto Rico) and Spain. Each participant was administered the Stroop test as part of a larger neuropsychological battery. The Stroop-Word, Stroop-Color, Stroop Word-Color and Stroop-Interference scores were normed using multiple linear regressions and standard deviations of residual values...
September 16, 2017: NeuroRehabilitation
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