keyword
https://read.qxmd.com/read/38656419/quiescent-adult-neural-stem-cells-developmental-origin-and-regulatory-mechanisms
#1
REVIEW
Han Meng, Yu Huan, Kun Zhang, Xuyang Yi, Xinyu Meng, Enming Kang, Shengxi Wu, Wenbing Deng, Yazhou Wang
The existence of neural stem cells (NSCs) in the adult mammalian nervous system, although small in number and restricted to the sub-ventricular zone of the lateral ventricles, the dentate gyrus of the hippocampus, and the olfactory epithelium, is a gift of evolution for the adaptive brain function which requires persistent plastic changes of these regions. It is known that most adult NSCs are latent, showing long cell cycles. In the past decade, the concept of quiescent NSCs (qNSCs) has been widely accepted by researchers in the field, and great progress has been made in the biology of qNSCs...
April 24, 2024: Neuroscience Bulletin
https://read.qxmd.com/read/38656206/utility-of-antibiotic-use-in-pediatric-facial-fractures-a-systematic-review
#2
JOURNAL ARTICLE
Jacqueline Tucker, Madison Oxford, Kasra Ziai, Jessyka G Lighthall
Background: In regard to antibiotic stewardship, it is important to understand the appropriate time to prescribe antibiotics in pediatric facial fracture management. Objective: To evaluate the utility of antibiotics in pediatric facial fractures and determine situational variables influencing appropriate antibiotic prescription. Methods: A comprehensive literature search was conducted in PubMed, Cochrane, and Web of Science databases for articles published from 2000 to 2022. Inclusion criteria consisted of all studies assessing pediatric facial fractures that mentioned antibiotic use...
April 24, 2024: Facial plastic surgery & aesthetic medicine
https://read.qxmd.com/read/38656151/a-review-of-current-achievements-and-recent-challenges-in-bacterial-medium-chain-length-polyhydroxyalkanoates-production-and-potential-applications
#3
REVIEW
Nahid Azizi, Reza Eslami, Shaghayegh Goudarzi, Habibollah Younesi, Hadis Zarrin
Using petroleum-derived plastics has contributed significantly to environmental issues, such as greenhouse gas emissions and the accumulation of plastic waste in ecosystems. Researchers have focused on developing ecofriendly polymers as alternatives to traditional plastics to address these concerns. This review provides a comprehensive overview of medium-chain-length polyhydroxyalkanoates (mcl-PHAs), biodegradable biopolymers produced by microorganisms that show promise in replacing conventional plastics. The review discusses the classification, properties, and potential substrates of less studied mcl-PHAs, highlighting their greater ductility and flexibility compared to poly(3-hydroxybutyrate), a well-known but brittle PHA...
April 24, 2024: Biomacromolecules
https://read.qxmd.com/read/38655103/the-posthyaluronidase-syndrome-dosing-strategies-for-hyaluronidase-in-the-dissolving-of-facial-filler-and-independent-predictors-of-poor-outcomes
#4
JOURNAL ARTICLE
Caroline L Wilde, Kailun Jiang, Sieun Lee, Daniel G Ezra
BACKGROUND: Hyaluronic acid dermal fillers are used extensively in periocular aesthetic medicine, and the incidence of filler-related complications is increasing. This study aimed to investigate the optimal dosing strategy for hyaluronidase and to identify predictors of poor outcomes. METHODS: We performed a retrospective review of 157 orbits of 90 patients treated with hyaluronidase over a 4-year period. Demographic data, indication, and details of hyaluronidase treatment and outcomes were recorded...
April 2024: Plastic and Reconstructive Surgery. Global Open
https://read.qxmd.com/read/38654968/audit-of-hemostatic-clip-use-after-colorectal-polyp-resection-in-an-academic-endoscopy-unit
#5
JOURNAL ARTICLE
Easton M Stark, Rachel E Lahr, Jeremiah Shultz, Krishna C Vemulapalli, John J Guardiola, Douglas K Rex
Background and study aims Prophylactic closure of endoscopic resection defects reduces delayed hemorrhage after resection of non-pedunculated colorectal lesions ≥ 20 mm that are located proximal to the splenic flexure and removed by electrocautery. The risk of delayed hemorrhage after cold (without electrocautery) resection is much lower, and prophylactic clip closure after cold resection is generally unnecessary. The aim of this study was to audit clip use after colorectal polyp resection in routine outpatient colonoscopies at two outpatient centers within an academic medical center...
April 2024: Endoscopy International Open
https://read.qxmd.com/read/38654714/sensing-in-the-dark-constructive-evolution-of-the-lateral-line-system-in-blind-populations-of-astyanax-mexicanus
#6
REVIEW
Roberto Rodríguez-Morales
Cave-adapted animals evolve a suite of regressive and constructive traits that allow survival in the dark. Most studies aiming at understanding cave animal evolution have focused on the genetics and environmental underpinnings of regressive traits, with special emphasis on vision loss. Possibly as a result of vision loss, other non-visual sensory systems have expanded and compensated in cave species. For instance, in many cave-dwelling fish species, including the blind cavefish of the Mexican tetra, Astyanax mexicanus , a major non-visual mechanosensory system called the lateral line, compensated for vision loss through morphological expansions...
April 2024: Ecology and Evolution
https://read.qxmd.com/read/38652864/surgical-management-of-airway-obstruction-following-posterior-pharyngeal-flap
#7
JOURNAL ARTICLE
Yanan Li, Xing Yin, Bing Shi, Jingtao Li
BACKGROUND: Posterior pharyngeal flap (PPF) is effective in managing velopharyngeal insufficiency (VPI) but is of airway obstruction risk. This study compared the effectiveness and complications of two PPF revision procedures and screened potential prognostic factors to postoperative hypernasality and persistent obstruction. METHODS: Patients who received flap division (FD) or port enlargement (PE) for airway obstruction following PPF were reviewed. Ventilation status was assessed using the nasal obstruction symptom evaluation (NOSE) scale, and velopharyngeal closure was assessed using subjective speech evaluation and nasopharyngoscopy...
April 23, 2024: Plastic and Reconstructive Surgery
https://read.qxmd.com/read/38651906/balamuthia-amebic-encephalitis-cured-and-discharged
#8
JOURNAL ARTICLE
Benda Qin, Liyan Jia, Jian Chen, Wei Liu
Intracerebral granulomatous infectious encephalitis caused by Baboon Balamuthia amoeba is a rare form of infectious granulomatous amoebic encephalitis. There are very limited case reports of cured discharges. The authors report a 59-year-old male patient who met the diagnostic criteria for granulomatous infection caused by Baboon Balamuthia amoeba. After treatment, the patient's condition improved, and he was discharged from the hospital. The authors reviewed the data of this patient, analyzed relevant imaging information, and summarized our experience to enhance understanding of this condition...
April 23, 2024: Journal of Craniofacial Surgery
https://read.qxmd.com/read/38651891/consideration-of-hyoid-variability-in-the-diagnostic-workup-of-fishbone-foreign-body-aspiration
#9
JOURNAL ARTICLE
Benjamin Harris Peterson Corman, Alexander Bjorling, Huseyin Isildak
Fishbone foreign body (FFB) can lodge in the upper respiratory or gastrointestinal tracts and frequently cause discomfort. While FFBs are common, variations in the hyoid may present radiographically similarly. The authors present a case in which a 32-year-old woman presented with pain in the right neck with a globus sensation after eating fish. Examination, including flexible fiberoptic laryngoscopy, did not reveal a foreign body. Given the patients' persistent symptoms, a noncontrast computed tomography was performed, demonstrating a radiopaque body superior to the right lateral hyoid bone, consistent with FFB...
April 23, 2024: Journal of Craniofacial Surgery
https://read.qxmd.com/read/38651655/anesthetic-challenges-in-patients-with-multicompartmental-lymphatic-failure-after-fontan-palliation-undergoing-transcatheter-thoracic-duct-decompression
#10
JOURNAL ARTICLE
Kirsten R Groody, Susan C Nicolson, David R Jobes
Lymphatic flow abnormalities are central to the development of protein losing enteropathy, plastic bronchitis, ascites and pleural effusions in patients palliated to the Fontan circulation. These complications can occur in isolation or multicompartmental (two or more). The treatment of multicompartmental lymphatic failure aims at improving thoracic duct drainage. Re-routing the innominate vein to the pulmonary venous atrium decompresses the thoracic duct, as atrial pressure is lower than systemic venous pressure in Fontan circulation...
April 23, 2024: Paediatric Anaesthesia
https://read.qxmd.com/read/38650456/recent-contributions-of-single-cell-and-spatial-profiling-to-the-understanding-of-bladder-cancer
#11
JOURNAL ARTICLE
Reinhard Grausenburger, Paula Herek, Shahrokh F Shariat, Bernhard Englinger
PURPOSE OF REVIEW: Current risk stratification and treatment decision-making for bladder cancer informed by histopathology as well as molecular diagnostics face limitations. This review summarizes recent advancements in single-cell and spatial omics methodologies for understanding bladder cancer biology and their potential impact on development of novel therapeutic strategies. RECENT FINDINGS: Single-cell RNA sequencing and spatial omics techniques offer unprecedented insights into various aspects of tumor microenvironment (TME), bladder cancer heterogeneity, cancer stemness, and cellular plasticity...
April 23, 2024: Current Opinion in Urology
https://read.qxmd.com/read/38649790/tree-water-uptake-patterns-across-the-globe
#12
REVIEW
Christoph Bachofen, Shersingh Joseph Tumber-Dávila, D Scott Mackay, Nate G McDowell, Andrea Carminati, Tamir Klein, Benjamin D Stocker, Maurizio Mencuccini, Charlotte Grossiord
Plant water uptake from the soil is a crucial element of the global hydrological cycle and essential for vegetation drought resilience. Yet, knowledge of how the distribution of water uptake depth (WUD) varies across species, climates, and seasons is scarce relative to our knowledge of aboveground plant functions. With a global literature review, we found that average WUD varied more among biomes than plant functional types (i.e. deciduous/evergreen broadleaves and conifers), illustrating the importance of the hydroclimate, especially precipitation seasonality, on WUD...
April 22, 2024: New Phytologist
https://read.qxmd.com/read/38649525/the-preservation-of-umbilical-blood-supply-in-combined-ventral-hernia-repair-and-abdominoplasty-a-narrative-review
#13
REVIEW
Marcel Chua, Ishith Seth, Vicky Tobin, Elan Kaplan, Warren Matthew Rozen
INTRODUCTION: Combined ventral hernia repair and abdominoplasty treat risk factors such as high body mass index and weak abdominal musculature, providing excellent intraoperative exposure and improved patient outcomes. Unfortunately, a combination of traditional procedures is unfeasible as the umbilical blood supply would be compromised, leading to increased umbilical necrosis risk. This narrative review aimed to identify new techniques and solidify evidence in preserving umbilical blood supply and associated level of evidence...
April 22, 2024: Aesthetic Plastic Surgery
https://read.qxmd.com/read/38649493/long-term-outcomes-of-fully-covered-self-expandable-metal-stents-for-refractory-biliary-strictures-after-living-donor-liver-transplantation-a-retrospective-study-at-a-tertiary-center
#14
JOURNAL ARTICLE
Sung Hyun Cho, Ho Seung Lee, Gunn Huh, Dongwook Oh, Tae Jun Song, Dong-Wan Seo, Sung Koo Lee
BACKGROUND AND AIMS: Endoscopic multiple plastic stents are an established first-line treatment for anastomotic biliary stricture (ABS) management after liver transplantation (LT). Fully covered self-expandable metallic stents (FCSEMSs) have recently been used with favorable outcomes, but long-term treatment outcomes remain an issue for ABS. We evaluated the long-term outcomes of FCSEMS for the management of refractory ABS after LT. METHODS: We reviewed the prospectively collected and maintained endoscopic retrograde cholangiography database at Asan Medical Center to retrieve consecutive post-LT ABS cases that underwent an endoscopic FCSEMS placement between August 2009 and August 2019 after MPS placement failure...
April 22, 2024: Surgical Endoscopy
https://read.qxmd.com/read/38649194/study-of-axonal-injury-and-degeneration-in-drosophila
#15
JOURNAL ARTICLE
Thomas J Waller, Laura J Smithson, Catherine A Collins
A fundamental feature of nervous systems is a highly specified synaptic connectivity between cells and the ability to adaptively change this connectivity through plasticity mechanisms. Plasticity mechanisms are highly relevant for responding to nervous system damage, and studies using nervous system injury paradigms in Drosophila (as well as other model organisms) have revealed conserved molecular pathways that are triggered by axon damage. Simple assays that introduce injuries to axons in either adult flies or larvae have proven to be particularly powerful for uncovering mechanisms of axonal degeneration and clearance...
April 22, 2024: Cold Spring Harbor Protocols
https://read.qxmd.com/read/38648531/invited-commentary-comparison-of-dorsal-preservation-rhinoplasty-techniques-functional-and-aesthetic-review-of-subdorsal-septal-strip-methods-by-barrera
#16
JOURNAL ARTICLE
Masoud Saman, Yves Saban
No abstract text is available yet for this article.
April 22, 2024: Facial plastic surgery & aesthetic medicine
https://read.qxmd.com/read/38648530/effectiveness-of-hyperbaric-oxygen-treatment-in-facial-plastic-and-reconstructive-surgery-a-systematic-review
#17
JOURNAL ARTICLE
Monica K Rossi Meyer, Cherian K Kandathil, Mikhail Saltychev, Eric X Wei, Sam P Most
No abstract text is available yet for this article.
April 22, 2024: Facial plastic surgery & aesthetic medicine
https://read.qxmd.com/read/38648529/comparison-of-dorsal-preservation-rhinoplasty-techniques-functional-and-aesthetic-review-of-subdorsal-septal-strip-methods
#18
JOURNAL ARTICLE
José Enrique Barrera
Objective: To compare subdorsal strip excisions in patients undergoing dorsal preservation (DP) rhinoplasty using patient-related outcome measures (PROMS). Methods: Patients were treated from 2020 to 2022 using the modified subdorsal strip method (MSSM) or Z flap approach. A two-sample t -test determined whether there was a difference in functional and aesthetic scores using the NOSE, Sinonasal Outcome Test (SNOT-22), SCHNOS, and ESS scales. Results: Seventy-one primary rhinoplasty patients met inclusion criteria at 12 months with an average age of 23 years (62 female, 9 male), with 35 (49%) undergoing the MSSM technique, while 36 (51%) receiving the Z flap...
April 22, 2024: Facial plastic surgery & aesthetic medicine
https://read.qxmd.com/read/38647815/retrospective-analysis-on-prognosis-of-oral-cancer-patients-according-to-surgical-approaches-for-effective-cancer-ablation-swing-approach-versus-visor-approach
#19
JOURNAL ARTICLE
Yun-Ho Kim, Jae-Young Yang, Dong-Min Lee, Jae-Yeol Lee, Dae-Seok Hwang, Mi-Heon Ryu, Uk-Kyu Kim
BACKGROUND: For the surgical treatment of oral cancer, it is sometimes necessary to expand intraoral access within the oral cavity. The "swing approach" that involves lip splitting of the mandible and temporary mandibular osteotomy and the "visor approach" that does not split the lower lip and mandible are mainly used. This study analyzed postoperative outcomes such as complications, recurrence rate, and survival rate by these two approaches. The goal of this study is to evaluate the surgical outcomes of patients using these two approaches, to propose effective perioperative management for oral cancer surgery, and to compare the prognosis of oral cancer patients...
April 22, 2024: Maxillofacial Plastic and Reconstructive Surgery
https://read.qxmd.com/read/38647525/positive-and-negative-durotaxis-mechanisms-and-emerging-concepts
#20
JOURNAL ARTICLE
Mathilde Mathieu, Aleksi Isomursu, Johanna Ivaska
Cell migration is controlled by the coordinated action of cell adhesion, cytoskeletal dynamics, contractility and cell extrinsic cues. Integrins are the main adhesion receptors to ligands of the extracellular matrix (ECM), linking the actin cytoskeleton to the ECM and enabling cells to sense matrix rigidity and mount a directional cell migration response to stiffness gradients. Most models studied show preferred migration of single cells or cell clusters towards increasing rigidity. This is referred to as durotaxis, and since its initial discovery in 2000, technical advances and elegant computational models have provided molecular level details of stiffness sensing in cell migration...
April 15, 2024: Journal of Cell Science
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