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Denver rct

Anne-Lise Jouen, Antonio Narzisi, Jean Xavier, Elodie Tilmont, Nicolas Bodeau, Valentina Bono, Nabila Ketem-Premel, Salvatore Anzalone, Koushik Maharatna, Mohamed Chetouani, Filippo Muratori, David Cohen
BACKGROUND: To meet the required hours of intensive intervention for treating children with autism spectrum disorder (ASD), we developed an automated serious gaming platform (11 games) to deliver intervention at home (GOLIAH) by mapping the imitation and joint attention (JA) subset of age-adapted stimuli from the Early Start Denver Model (ESDM) intervention. Here, we report the results of a 6-month matched controlled exploratory study. METHODS: From two specialized clinics, we included 14 children (age range 5-8 years) with ASD and 10 controls matched for gender, age, sites, and treatment as usual (TAU)...
2017: Child and Adolescent Psychiatry and Mental Health
Paul Wurzer, Ludwik K Branski, Robert P Clayton, Gabriel Hundeshagen, Abigail A Forbes, Charles D Voigt, Clark R Andersen, Lars-P Kamolz, Lee C Woodson, Oscar E Suman, Celeste C Finnerty, David N Herndon
PURPOSE: The aim of this study was to quantify the effect of propranolol on hemodynamic parameters assessed using the PiCCO system in burned children. METHODS: We analyzed hemodynamic data from patients who were randomized to receive either propranolol (4 mg/kg/day) or placebo (control), which was initiated as a prospective randomized controlled trial. Endpoints were cardiac index (CI), percent predicted heart rate (%HR), mean arterial pressure (MAP), percent predicted stroke volume (%SV), rate pressure product (RPP), cardiac work (CW), systemic vascular resistance index (SVRI), extravascular lung water index (EVLWI), arterial blood gases, events of lactic acidosis, and mortality...
November 2016: Shock
Kayce H Ryberg
BACKGROUND: The Early Start Denver Model (ESDM) is a manualized comprehensive therapy for toddlers with autism spectrum disorder. It emphasizes interpersonal engagement through synchrony, rhythms, and reciprocity to decrease symptom severity and accelerate cognitive, social-emotional, and language development. OBJECTIVE: To systematically review evidence regarding the use of the ESDM as an intervention for young children with autism spectrum disorder. DESIGN: PubMed, Scopus, Web of Science, Embase, and CINAHL were searched from 2010-2015 using predetermined inclusion criteria...
September 2015: Journal of the American Psychiatric Nurses Association
Jennifer E Stevens-Lapsley, Brian J Loyd, Jason R Falvey, Greg J Figiel, Andrew J Kittelson, Ethan U Cumbler, Kathleen K Mangione
OBJECTIVE: To determine whether a progressive multicomponent physical therapy intervention in the home setting can improve functional mobility for deconditioned older adults following acute hospitalization. DESIGN: Randomized controlled trial. SETTING: Patient homes in the Denver, CO, metropolitan area. PARTICIPANTS: A total of 22 homebound older adults age 65 and older (mean ± SD; 85.4 ±7.83); 12 were randomized to intervention group and 10 to the control group...
August 2016: Clinical Rehabilitation
Thomas N Robinson, Christina L Dunn, Jill C Adams, Carrie L Hawkins, Zung V Tran, Christopher D Raeburn, Marc Moss
OBJECTIVES: To determine whether the postoperative administration of tryptophan would be beneficial for elderly adults undergoing surgery who are at risk of developing postoperative delirium. DESIGN: Randomized, double-blind, placebo-controlled trial. SETTING: Denver Veterans Affairs Medical Center. PARTICIPANTS: Individuals aged 60 and older undergoing major elective operations requiring a postoperative intensive care unit (ICU) admission (n = 325)...
September 2014: Journal of the American Geriatrics Society
Anthony Jerant, Richard L Kravitz, Nancy Sohler, Kevin Fiscella, Raquel L Romero, Bennett Parnes, Daniel J Tancredi, Sergio Aguilar-Gaxiola, Christina Slee, Simon Dvorak, Charles Turner, Andrew Hudnut, Francisco Prieto, Peter Franks
PURPOSE: Interventions tailored to sociopsychological factors associated with health behaviors have promise for reducing colorectal cancer screening disparities, but limited research has assessed their impact in multiethnic populations. We examined whether an interactive multimedia computer program (IMCP) tailored to expanded health belief model sociopsychological factors could promote colorectal cancer screening in a multiethnic sample. METHODS: We undertook a randomized controlled trial, comparing an IMCP tailored to colorectal cancer screening self-efficacy, knowledge, barriers, readiness, test preference, and experiences with a nontailored informational program, both delivered before office visits...
May 2014: Annals of Family Medicine
Bo Wang, Siyan Zhan, Ting Gong, Liming Lee
BACKGROUND: Iron deficiency and iron deficiency anaemia (IDA) are common in young children. It has been suggested that the lack of iron may have deleterious effects on children's psychomotor development and cognitive function. To evaluate the benefits of iron therapy on psychomotor development and cognitive function in children with IDA, a Cochrane review was carried out in 2001. This is an update of that review. OBJECTIVES: To determine the effects of iron therapy on psychomotor development and cognitive function in iron deficient anaemic children less than three years of age...
June 6, 2013: Cochrane Database of Systematic Reviews
Theresa Mickiewicz, Alia Al-Tayyib, Mark Thrun, Cornelis Rietmeijer
BACKGROUND: Partner notification of exposure to gonorrhea or chlamydia is traditionally conducted by the index case or a disease intervention specialist. However, a significant proportion of partners remain untreated and thus are at risk for continued transmission. Expedited partner therapy (EPT) obviates the requirement for a health care visit by the partner: the index case delivers medications to the partner. Although shown to be efficacious in randomized control trials, effectiveness studies of delivering EPT in real-world situations are needed...
December 2012: Sexually Transmitted Diseases
Sally J Rogers, Annette Estes, Catherine Lord, Laurie Vismara, Jamie Winter, Annette Fitzpatrick, Mengye Guo, Geraldine Dawson
OBJECTIVE: This study was carried out to examine the efficacy of a 12-week, low-intensity (1-hour/wk of therapist contact), parent-delivered intervention for toddlers at risk for autism spectrum disorders (ASD) aged 14 to 24 months and their families. METHOD: A randomized controlled trial involving 98 children and families was carried out in three different sites investigating the efficacy of a parent delivery of the Early Start Denver model (P-ESDM), which fosters parental use of a child-centered responsive interaction style that embeds many teaching opportunities into play, compared to community treatment as usual...
October 2012: Journal of the American Academy of Child and Adolescent Psychiatry
Lori A Crane, Nancy L Asdigian, Anna E Barón, Jenny Aalborg, Alfred C Marcus, Stefan T Mokrohisky, Tim E Byers, Robert P Dellavalle, Joseph G Morelli
BACKGROUND: Sun exposure, especially during childhood, is the most important preventable risk factor for skin cancer, yet few effective interventions to reduce exposure exist. PURPOSE: To test the effectiveness of a partially tailored mailed intervention based on the Precaution Adoption Process Model, delivered in the spring over 3 years to parents and children. DESIGN: RCT, with data collection through telephone interviews of parents and skin exams of children at baseline (Summer 2004) and annually (Summer 2005-2007)...
October 2012: American Journal of Preventive Medicine
Christina A Suh, Alison Saville, Matthew F Daley, Judith E Glazner, Jennifer Barrow, Shannon Stokley, Fran Dong, Brenda Beaty, L Miriam Dickinson, Allison Kempe
OBJECTIVE: To assess the effectiveness of reminder/recall (R/R) for immunizing adolescents in private pediatric practices and to describe the associated costs and revenues. METHODS: We conducted a randomized controlled trial in 4 private pediatric practices in metropolitan Denver. In each practice, 400 adolescents aged 11 to 18 years who had not received 1 or more targeted vaccinations (tetanus-diphtheria-acellular pertussis, meningococcal conjugate, or first dose of human papillomavirus vaccine for female patients) were randomly selected and randomized to intervention (2 letters and 2 telephone calls) or control (usual care) groups...
June 2012: Pediatrics
Allison Kempe, Jennifer Barrow, Shannon Stokley, Alison Saville, Judith E Glazner, Christina Suh, Steven Federico, Lisa Abrams, Laura Seewald, Brenda Beaty, Matthew F Daley, L Miriam Dickinson
BACKGROUND AND OBJECTIVE: Effectiveness of recall for immunizations has not been examined in the setting of school-based health centers (SBHCs). We assessed (1) immunization rates achieved with recall among sixth-grade girls (demonstration study); (2) effectiveness of recall among sixth-grade boys (randomized controlled trial [RCT]); and (3) cost of conducting recall in SBHCs. METHODS: During October 2008 through March 2009, in 4 Denver public SBHCs, we conducted (1) a demonstration study among 265 girls needing ≥ 1 recommended adolescent vaccine and (2) an RCT among 264 boys needing vaccines, with half randomized to recall and half receiving usual care...
June 2012: Pediatrics
David J Magid, P Michael Ho, Kari L Olson, David W Brand, Lesley K Welch, Karen E Snow, Anne C Lambert-Kerzner, Mary E Plomondon, Edward P Havranek
OBJECTIVE: To determine if a multimodal intervention composed of patient education, home blood pressure (BP) monitoring, BP measurement reporting to an interactive voice response (IVR) phone system, and clinical pharmacist follow-up improves BP control compared with usual care. STUDY DESIGN: Prospective study with patient enrollment, medication consultation and adjustment, remote BP monitoring, and follow-up at 6 months. METHODS: This randomized controlled trial was conducted at 3 healthcare systems in Denver, Colorado, including a large health maintenance organization, a Veterans Affairs medical center, and a county hospital...
April 2011: American Journal of Managed Care
Zachary Warren, Melissa L McPheeters, Nila Sathe, Jennifer H Foss-Feig, Allison Glasser, Jeremy Veenstra-Vanderweele
CONTEXT: Early intensive behavioral and developmental interventions for young children with autism spectrum disorders (ASDs) may enhance developmental outcomes. OBJECTIVE: To systematically review evidence regarding such interventions for children aged 12 and younger with ASDs. METHODS: We searched Medline, PsycINFO, and ERIC (Education Resources Information Center) from 2000 to May 2010. Two reviewers independently assessed studies against predetermined inclusion/exclusion criteria...
May 2011: Pediatrics
Heather N Taussig, Sara E Culhane
OBJECTIVE: To evaluate the efficacy of the Fostering Healthy Futures program in reducing mental health problems and associated problems. DESIGN: Randomized controlled trial. SETTING: Denver metropolitan area. PARTICIPANTS: Children aged 9 to 11 years who were maltreated and placed in foster care. INTERVENTION: Children in the control group (n=77) received an assessment of their cognitive, educational, and mental health functioning...
August 2010: Archives of Pediatrics & Adolescent Medicine
Edwin H Cook
No abstract text is available yet for this article.
February 2010: Autism Research: Official Journal of the International Society for Autism Research
Geraldine Dawson, Sally Rogers, Jeffrey Munson, Milani Smith, Jamie Winter, Jessica Greenson, Amy Donaldson, Jennifer Varley
OBJECTIVE: To conduct a randomized, controlled trial to evaluate the efficacy of the Early Start Denver Model (ESDM), a comprehensive developmental behavioral intervention, for improving outcomes of toddlers diagnosed with autism spectrum disorder (ASD). METHODS: Forty-eight children diagnosed with ASD between 18 and 30 months of age were randomly assigned to 1 of 2 groups: (1) ESDM intervention, which is based on developmental and applied behavioral analytic principles and delivered by trained therapists and parents for 2 years; or (2) referral to community providers for intervention commonly available in the community...
January 2010: Pediatrics
Jenny Aalborg, Joseph G Morelli, Stefan T Mokrohisky, Nancy L Asdigian, Tim E Byers, Robert P Dellavalle, Neil F Box, Lori A Crane
OBJECTIVE: To examine the relationship between tanning and nevus development in very-light-skinned children. DESIGN: Prospective cohort nested within a randomized controlled trial. Skin examinations in 3 consecutive years (2004, 2005, and 2006) included full-body counts of nevi, skin color and tanning measurement using colorimetry, and hair and eye color evaluation by comparison with charts. Telephone interviews of parents provided sun exposure, sun protection, and sunburn history...
September 2009: Archives of Dermatology
Glenn Gade, Ingrid Venohr, Douglas Conner, Kathleen McGrady, Jeffrey Beane, Robert H Richardson, Marilyn P Williams, Marcia Liberson, Mark Blum, Richard Della Penna
BACKGROUND: Palliative care improves care and reduces costs for hospitalized patients with life-limiting illnesses. There have been no multicenter randomized trials examining impact on patient satisfaction, clinical outcomes, and subsequent health care costs. OBJECTIVE: Measure the impact of an interdisciplinary palliative care service (IPCS) on patient satisfaction, clinical outcomes, and cost of care for 6 months posthospital discharge. METHODS: Multicenter, randomized, controlled trial...
March 2008: Journal of Palliative Medicine
Louise Hickson, Linda Worrall, Nerina Scarinci
OBJECTIVE: To evaluate the effectiveness of the Active Communication Education (ACE) program for older people with hearing impairment and to investigate factors that influence response to the program. The ACE is a group program that runs for 2 hr per week for 5 wk. DESIGN: In this double-blinded, randomized, controlled trial, 178 older people with, on average, mild to moderate hearing impairment were randomly allocated to one of two groups. Approximately half had been fitted with hearing aid/s in the past...
April 2007: Ear and Hearing
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