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https://www.readbyqxmd.com/read/28799874/limitations-of-multidetector-computed-tomography-angiography-for-the-diagnosis-of-blunt-cerebrovascular-injury
#1
Ramesh Grandhi, Gregory M Weiner, Nitin Agarwal, David M Panczykowski, William J Ares, Jesse S Rodriguez, Jonathan A Gelfond, John G Myers, Louis H Alarcon, David O Okonkwo, Brian T Jankowitz
OBJECTIVE Blunt cerebrovascular injuries (BCVIs) following trauma carry risk for morbidity and mortality. Since patients with BCVI are often asymptomatic at presentation and neurological sequelae often occur within 72 hours, timely diagnosis is essential. Multidetector CT angiography (CTA) has been shown to be a noninvasive, cost-effective, reliable means of screening; however, the false-positive rate of CTA in diagnosing patients with BCVI represents a key drawback. Therefore, the authors assessed the role of DSA in the screening of BCVI when utilizing CTA as the initial screening modality...
August 11, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28799744/influence-of-superhydrophobicity-on-the-bactericidal-efficiency-of-black-silicon-surfaces
#2
Denver Paige Linklater, Saulius Juodkazis, Sergey Rubanov, Elena P Ivanova
The recent discovery of nanostructured surfaces induced rupturing of bacterial cells has seen a surge in the development of surfaces for the physical killing of bacteria towards the fight against bacterial colonisation of abiotic surfaces. It is established that the nanoarchitecture is directly responsible for the inactivation of bacterial cells; however the mechanobactericidal action remains to be fully elucidated. Here we report the fabrication of superhydrophilic and superhydrophobic black silicon surfaces with well-defined surface geometries and wettability which are responsible for inactivating approximately 98% of P...
August 11, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28777204/better-completion-of-pediatric-latent-tuberculosis-treatment-using-4-months-of-rifampin-in-a-us-based-tuberculosis-clinic
#3
James Gaensbauer, Kaylynn Aiona, Michelle Haas, Randall Reves, Janine Young, Robert Belknap
BACKGROUND: Children less than five years of age have the highest age-specific rate of progression from latent tuberculosis infection (LTBI) to active disease. Therefore, regimens for treatment of pediatric LTBI must be not only efficacious but practical enough to overcome the unique childhood barriers to regimen adherence. Since 2012, a 4-month regimen of daily rifampin (4R) has been the standard recommendation for pediatric LTBI at the Denver Metro Tuberculosis Clinic (DMTBC). METHODS: Using univariate and multivariate analysis, we compared treatment completion rates between 4R and 9-month isoniazid (9H) regimens for all pediatric patients treated for LTBI at the DMTBC between 1/1/2006 and 12/31/2015, and assessed the influence of clinical and demographic characteristics on successful completion of the two regimens...
August 1, 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/28763391/spatial-surveillance-of-childhood-lead-exposure-in-a-targeted-screening-state-an-application-of-generalized-additive-models-in-denver-colorado
#4
Kevin Berg, Stephanie Kuhn, Mike Van Dyke
CONTEXT: The targeted nature of Colorado's childhood lead screening program presents several analytical issues that complicate routine epidemiologic surveillance. OBJECTIVES: To analyze spatial patterns of childhood lead exposure among children younger than 6 years, identifying areas of increased risk along with associated covariates. METHODS: We analyzed a spatial case-control data set of childhood lead poisoning using generalized additive models...
September 2017: Journal of Public Health Management and Practice: JPHMP
https://www.readbyqxmd.com/read/28750758/50-years-ago-in-the-journal-of-pediatrics-the-denver-developmental-screening-test
#5
Jennifer Accardo, Pasquale Accardo
No abstract text is available yet for this article.
August 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28741167/microvascular-ultrastructural-changes-precede-cognitive-impairment-in-the-murine-appswe-ps1de9-model-of-alzheimer-s-disease
#6
Patricia Kelly, Paul Denver, Simon C Satchell, Maximilian Ackermann, Moritz A Konerding, Christopher A Mitchell
Cerebral and systemic organ microvascular pathologies coexist with human Alzheimer's disease (AD) neuropathology. In this study, we hypothesised that both cerebral and systemic microvascular pathologies exist in 4- to 5-month-old male APPswe/PS1dE9 (APP/PS1) transgenic mice prior to the onset of cognitive impairment. To assess this we examined recognition memory in both wild-type and APP/PS1 mice using the object recognition task (ORT; n = 11 per group) and counted thioflavin-S-positive plaques in brain (n = 6 per group)...
July 25, 2017: Angiogenesis
https://www.readbyqxmd.com/read/28738815/transcription-through-the-eye-of-a-needle-daily-and-annual-cyclic-gene-expression-variation-in-douglas-fir-needles
#7
Richard Cronn, Peter C Dolan, Sanjuro Jogdeo, Jill L Wegrzyn, David B Neale, J Bradley St Clair, Dee R Denver
BACKGROUND: Perennial growth in plants is the product of interdependent cycles of daily and annual stimuli that induce cycles of growth and dormancy. In conifers, needles are the key perennial organ that integrates daily and seasonal signals from light, temperature, and water availability. To understand the relationship between seasonal cycles and seasonal gene expression responses in conifers, we examined diurnal and circannual needle mRNA accumulation in Douglas-fir (Pseudotsuga menziesii) needles at diurnal and circannual scales...
July 24, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28737667/prenatal-vitamin-d-intake-cord-blood-25-hydroxyvitamin-d-and-offspring-body-composition-the-healthy-start-study
#8
Katherine A Sauder, Hallie J Koeppen, Allison L B Shapiro, Kathryn E Kalata, Alexandra V Stamatoiu, Brandy M Ringham, Deborah H Glueck, Jill M Norris, Dana Dabelea
Vitamin D deficiency in pregnancy may be associated with increased offspring adiposity, but evidence from human studies is inconclusive. We examined associations between prenatal vitamin D intake, 25-hydroxyvitamin D (25(OH)D) in cord blood, and offspring size and body composition at birth and 5 months. Participants included 605 mother-offspring dyads from the Healthy Start study, an ongoing, pre-birth prospective cohort study in Denver, Colorado, USA. Prenatal vitamin D intake was assessed with diet recalls and questionnaires, and offspring body composition was measured via air displacement plethysmography at birth and 5 months...
July 22, 2017: Nutrients
https://www.readbyqxmd.com/read/28734745/why-are-some-people-who-have-received-overdose-education-and-naloxone-reticent-to-call-emergency-medical-services-in-the-event-of-overdose
#9
Stephen Koester, Shane R Mueller, Lisa Raville, Sig Langegger, Ingrid A Binswanger
BACKGROUND: Overdose Education and Naloxone Distribution (OEND) training for persons who inject drugs (PWID) underlines the importance of summoning emergency medical services (EMS). To encourage PWID to do so, Colorado enacted a Good Samaritan law providing limited immunity from prosecution for possession of a controlled substance and/or drug paraphernalia to the overdose victim and the witnesses who in good faith provide emergency assistance. This paper examines the law's influence by describing OEND trained PWIDs' experience reversing overdoses and their decision about calling for EMS support...
July 19, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/28727472/relieving-dry-mouth-varying-levels-of-ph-found-in-bottled-water
#10
Bailey Jean Fisher, Angela Spencer, Van Haywood, Gayathri Konchady
It is estimated that 30% of people older than 60 years suffer from hyposalivation or dry mouth. Drinking water frequently has been recommended as a safe, non-pharmacologic way to combat hyposalivation. The saliva in patients with dry mouth is acidic. Beverages consumed daily may have an erosive potential on teeth. The pH and the mineral content of the beverage determine its erosive potential. An acidic beverage, therefore, may have harmful effects on mineralized tooth structures, causing erosion of enamel, dentin, and cementum...
July 2017: Compendium of Continuing Education in Dentistry
https://www.readbyqxmd.com/read/28715172/a-spatiotemporal-industrial-activity-model-for-estimating-the-intensity-of-oil-and-gas-operations-in-colorado
#11
William B Allshouse, John L Adgate, Benjamin D Blair, Lisa M McKenzie
Oil and gas (O&G) production in the United States has increased in the last 15 years and operations, which are trending towards large multi-well pads, release hazardous air pollutants. Health studies have relied on proximity to O&G wells as an exposure metric, typically using an inverse distance weighting (IDW) approach. Since O&G emissions are dependent on multiple factors, a dynamic model is needed to describe the variability in air pollution emissions over space and time. We used information on Colorado O&G activities, production volumes, and air pollutant emission rates from two Colorado basins to create a spatiotemporal industrial activity model to develop an intensity-adjusted IDW well count metric...
July 17, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28706309/the-draft-genome-of-globodera-ellingtonae
#12
Wendy S Phillips, Dana K Howe, Amanda M V Brown, Sebastian Eves-van den Akker, Levi Dettwyler, Amy B Peetz, Dee R Denver, Inga A Zasada
Globodera ellingtonae is a newly described potato cyst nematode (PCN) found in Idaho, Oregon, and Argentina. Here, we present a genome assembly for G. ellingtonae, a relative of the quarantine nematodes G. pallida and G. rostochiensis, produced using data from Illumina and Pacific Biosciences DNA sequencing technologies.
June 2017: Journal of Nematology
https://www.readbyqxmd.com/read/28706308/introduction-to-nematode-genome-and-transcriptome-announcements-in-the-journal-of-nematology
#13
Dee R Denver, Erik J Ragsdale, W Kelley Thomas, Inga A Zasada
The Journal of Nematology now offers publication of Nematode Genome Announcements (NGA) and Nematode Transcriptome Announcements (NTA). These brief reports announce the sequencing and assembly of a nematode genome or transcriptome resource, along with basic technical information on DNA sequencing and bioinformatic methods used. This publishing initiative offers a new avenue to openly and concisely communicate the availability and relevance of genome and transcriptome sequence resources to the broader scientific community...
June 2017: Journal of Nematology
https://www.readbyqxmd.com/read/28695610/anion-gap-can-differentiate-between-psychogenic-and-epileptic-seizures-in-the-emergency-setting
#14
Yi Li, Liesl Matzka, Louise Maranda, Daniel Weber
Differentiation between psychogenic nonepileptic seizures (PNES) and generalized convulsive epileptic seizures (ES) is important for appropriate triaging in the emergency department (ED). This can be difficult in the ED, as the event is often not witnessed by a medical professional. In the current study, we investigated whether anion gap (AG), bicarbonate, and the Denver Seizure Score (DSS) could differentiate between PNES and ES. Of a total of 1,354 subjects reviewed from a tertiary care medical center, 27 PNES and 27 ES patients were identified based on clinical description and subsequent electroencephalogram...
July 11, 2017: Epilepsia
https://www.readbyqxmd.com/read/28694274/challenges-for-insured-patients-in-accessing-behavioral-health-care
#15
MariaElena O Williams, Jamie R Gilroy, Tae Y Chang, Deborah J Seymour
The Patient Protection and Affordable Care Act (ACA) mandates that health insurance plans include sufficient access to behavioral health providers, but lacks specific guidelines to define sufficient access Using a secret shopper methodology, we called behavioral health providers in the Denver metropolitan area networked with 3 large insurance companies. We found that, depending on insurance company and level of training, 9.8% to 59% of providers could offer a new patient appointment, with psychiatry appointments being particularly difficult to schedule...
July 2017: Annals of Family Medicine
https://www.readbyqxmd.com/read/28693007/dr-bibbo-s-presidential-address-on-automation-in-cytology-were-her-predictions-right-wrong-or-somewhere-in-the-middle
#16
David C Wilbur
In 1983, Dr. Marluce Bibbo gave the Presidential Address at the Annual Meeting of the American Society of Cytology in Denver, CO, USA. The lecture was entitled "Analytic and Quantitative Cytology," a field in which Dr. Bibbo was intimately involved. In the presentation, she included a summary of 30 years of work already accomplished, the present state of the art, and musings about issues encountered, potential resolutions, progress that needed to be made, and her perception of how the field needed to evolve in order to become ultimately successful as a clinical service...
2017: Acta Cytologica
https://www.readbyqxmd.com/read/28686682/a-road-damage-and-life-cycle-greenhouse-gas-comparison-of-trucking-and-pipeline-water-delivery-systems-for-hydraulically-fractured-oil-and-gas-field-development-in-colorado
#17
Ray C Duthu, Thomas H Bradley
The process of hydraulic fracturing for recovery of oil and natural gas uses large amounts of fresh water and produces a comparable amount of wastewater, much of which is typically transported by truck. Truck transport of water is an expensive and energy-intensive process with significant external costs including roads damages, and pollution. The integrated development plan (IDP) is the industry nomenclature for an integrated oil and gas infrastructure system incorporating pipeline-based transport of water and wastewater, centralized water treatment, and high rates of wastewater recycling...
2017: PloS One
https://www.readbyqxmd.com/read/28685407/evaluating-the-social-validity-of-the-early-start-denver-model-a-convergent-mixed-methods-study
#18
Emily Ogilvie, Matthew T McCrudden
An intervention has social validity to the extent that it is socially acceptable to participants and stakeholders. This pilot convergent mixed methods study evaluated parents' perceptions of the social validity of the Early Start Denver Model (ESDM), a naturalistic behavioral intervention for children with autism. It focused on whether the parents viewed (a) the ESDM goals as appropriate for their children, (b) the intervention procedures as acceptable and appropriate, and (c) whether changes in their children's behavior was practically significant...
July 6, 2017: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/28682941/reduction-in-mortality-rates-of-postinjury-multiple-organ-dysfunction-syndrome-a-shifting-paradigm-a-prospective-population-based-cohort-study
#19
Karlijn J P van Wessem, Luke P H Leenen
INTRODUCTION: The incidence of Multiple Organ Dysfunction Syndrome (MODS) has decreased in the last decade by improvement in trauma care. However, it still remains a major cause of morbidity and mortality. This study investigated the current incidence and mortality of MODS in polytrauma patients. MATERIALS AND METHODS: A 3-year prospective study included consecutive trauma patients admitted to a Level-1 Trauma Center ICU. Isolated head injuries, drowning, asphyxiation and burns were excluded...
July 4, 2017: Shock
https://www.readbyqxmd.com/read/28665698/an-official-american-thoracic-society-workshop-report-noninvasive-identification-of-inspiratory-flow-limitation-in-sleep-studies
#20
Sushmita Pamidi, Susan Redline, David Rapoport, Indu Ayappa, Luciana Palombini, Ramon Farre, Jason Kirkness, Jean-Louis Pépin, Olli Polo, Andrew Wellman, R John Kimoff
This report summarizes the proceedings of the American Thoracic Society Workshop on the Noninvasive Identification of Inspiratory Flow Limitation in Sleep Studies held on May 16, 2015, in Denver, Colorado. The goal of the workshop was to discuss methods for standardizing the scoring of flow limitation from nasal cannula pressure tracings. The workshop began with presentations on the physiology underlying flow limitation, existing methods of scoring flow limitation, the effects of signal acquisition and filtering on flow shapes, and a review of the literature examining the adverse outcomes related to flow limitation...
July 2017: Annals of the American Thoracic Society
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