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https://www.readbyqxmd.com/read/29140434/managing-public-health-data-mobile-applications-and-mass-vaccination-campaigns
#1
Melissa W McClung, Sarah A Gumm, Megan E Bisek, Amber L Miller, Bryan C Knepper, Arthur J Davidson
In response to data collection challenges during mass immunization events, Denver Public Health developed a mobile application to support efficient public health immunization and prophylaxis activities. The Handheld Automated Notification for Drugs and Immunizations (HANDI) system has been used since 2012 to capture influenza vaccination data during Denver Health's annual employee influenza campaign. HANDI has supported timely and efficient administration and reporting of influenza vaccinations through standardized data capture and database entry...
November 13, 2017: Journal of the American Medical Informatics Association: JAMIA
https://www.readbyqxmd.com/read/29132208/organic-chemical-characterization-and-mass-balance-of-a-hydraulically-fractured-well-from-fracturing-fluid-to-produced-water-over-405-days
#2
James S Rosenblum, E Michael Thurman, Imma Ferrer, George R Aiken, Karl G Linden
A long-term field study (405 days) of a hydraulically fractured well from the Niobrara Formation in the Denver-Julesburg Basin was completed. Characterization of organic chemicals used in hydraulic fracturing and their changes through time, from the pre-injected fracturing fluid to the produced water, was conducted. The characterization consisted of a mass balance by dissolved organic carbon (DOC), volatile organic analysis by gas chromatography/mass spectrometry, and nonvolatile organic analysis by liquid chromatography/mass spectrometry...
November 14, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/29119588/an-early-pregnancy-unit-in-the-united-states-an-effective-method-for-evaluating-first-trimester-pregnancy-complications
#3
Polina Rovner, Elaine Stickrath, Meredith Alston, Kirsten Lund
In the United Kingdom, early pregnancy assessment clinics have existed since the early 1990s and have become the reference standard for evaluating and treating women with first-trimester pregnancy complications. These units have now been established in many countries and have been found to be effective and efficient, saving money and unnecessary emergency department visits and hospital admissions. To our knowledge, no such model has been described in the United States. A PubMed search using a combination of "early pregnancy unit," "early pregnancy assessment clinic," and "United States," "U...
November 9, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/29104681/association-between-beta-sympathomimetic-tocolysis-and-risk-of-autistic-spectrum-disorders-behavioural-and-developmental-outcome-in-toddlers
#4
Mengühan Araz Altay, Işık Görker, Rakhshanda Aslanova, Leyla Bozatlı, Nesrin Turan, Petek Balkanlı Kaplan
AIM: To investigate whether maternal intravenous beta-mimetic tocolytic therapy increases the risk of autistic spectrum disorders (ASD) and poorer behavioural and developmental outcomes. METHOD: Our study is a prospective case-control study among 90 children between 1.5 and three years old. Cases (n = 46) were toddlers with betamimetic tocolytic exposure; control group toddlers (n = 44) were tocolytic untreated. Treated and untreated groups were also divided into subgroups: term and preterm delivered...
October 15, 2017: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29102960/new-frontiers-in-treating-uremic-metabolic-acidosis
#5
EDITORIAL
Denver Brown, Michal L Melamed
No abstract text is available yet for this article.
November 4, 2017: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/29096415/associations-of-adolescent-weight-status-and-meeting-national-obesity-related-recommendations
#6
Jessica A Cook, Emily V McCormick, Theresa E Mickiewicz, Arthur J Davidson, Deborah S Main
BACKGROUND: Adolescent overweight and obesity are serious health risks, with prevalence varying by sociodemographic group. Studies link children's weight status and sex/race-ethnic differences with meeting recommendations for physical activity and diet. But, research examining the intersection of sociodemographic characteristics, behavior, and weight status is limited. This paper aims to identify sociodemographic differences in the association between adolescent weight status and meeting 6 national obesity-related recommendations...
December 2017: Journal of School Health
https://www.readbyqxmd.com/read/29096412/stakeholder-perspectives-on-optimizing-communication-in-a-school-centered-asthma-program
#7
Hylke M Snieder, Sarah Nickels, Melanie Gleason, Arthur McFarlane, Stanley J Szefler, Mandy A Allison
BACKGROUND: School-centered asthma programs (SAPs) can be an effective intervention to improve asthma control for underserved populations but little is known about how key stakeholders communicate within these programs. Therefore, our aim was to identify key components of effective communication in a SAP. METHODS: Primary care providers (PCPs), parents and school nurses associated with a SAP in Denver, Colorado participated in interviews and focus groups about their views on effective communication...
December 2017: Journal of School Health
https://www.readbyqxmd.com/read/29082999/nanofabrication-of-mechano-bactericidal-surfaces
#8
REVIEW
Denver P Linklater, Saulius Juodkazis, Elena P Ivanova
The search for alternatives to the standard methods of preventing bacterial adhesion and biofilm formation on biotic and abiotic surfaces alike has led to the use of biomimetics to reinvent through nanofabrication methods, surfaces, whereby the nanostructured topography is directly responsible for bacterial inactivation through physico-mechanical means. Plant leaves, insect wings, and animal skin have been used to inspire the fabrication of synthetic high-aspect-ratio nanopillared surfaces, which can resist bacterial colonisation...
November 9, 2017: Nanoscale
https://www.readbyqxmd.com/read/29073903/characterizing-endophytic-competence-and-plant-growth-promotion-of-bacterial-endophytes-inhabiting-the-seed-endosphere-of-rice
#9
Denver I Walitang, Kiyoon Kim, Munusamy Madhaiyan, Young Kee Kim, Yeongyeong Kang, Tongmin Sa
BACKGROUND: Rice (Oryza sativa L. ssp. indica) seeds as plant microbiome present both an opportunity and a challenge to colonizing bacterial community living in close association with plants. Nevertheless, the roles and activities of bacterial endophytes remain largely unexplored and insights into plant-microbe interaction are compounded by its complexity. In this study, putative functions or physiological properties associated with bacterial endophytic nature were assessed. Also, endophytic roles in plant growth and germination that may allow them to be selectively chosen by plants were also studied...
October 26, 2017: BMC Microbiology
https://www.readbyqxmd.com/read/29073472/epilepsy-may-be-the-major-risk-factor-of-mental-retardation-in-children-with-tuberous-sclerosis-a-retrospective-cohort-study
#10
Yang-Yang Wang, Ling-Yu Pang, Shu-Fang Ma, Meng-Na Zhang, Li-Ying Liu, Li-Ping Zou
Mental retardation (MR) is one of the most common cognitive comorbidities in children with tuberous sclerosis, and there are enormous studies about its risk factors. The genetic difference and the severity of epilepsy are the two main factors, but their weight in the occurrence of MR is still unclear. Two hundred twenty-three patients with tuberous sclerosis who received intelligence assessment, genetic mutation analysis, and the epilepsy severity assessment were included in our study. Genotype-neurocognitive phenotype correlations and epilepsy-neurocognitive phenotype correlations were analyzed by binary logistic regression analysis...
October 23, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29069345/adaptive-evolution-under-extreme-genetic-drift-in-oxidatively-stressed-caenorhabditis-elegans
#11
Stephen F Christy, Riana I Wernick, Michael J Lue, Griselda Velasco, Dana K Howe, Dee R Denver, Suzanne Estes
A mutation-accumulation (MA) experiment with Caenorhabditis elegans nematodes was conducted in which replicate, independently evolving lines were initiated from a low-fitness mitochondrial electron transport chain mutant, gas-1 . The original intent of the study was to assess the effect of ETC dysfunction involving elevated reactive oxygen species (ROS) production on patterns of spontaneous germline mutation. In contrast to results of standard MA experiments, gas-1 MA lines evolved slightly higher mean fitness alongside reduced among-line genetic variance compared to their ancestor...
October 23, 2017: Genome Biology and Evolution
https://www.readbyqxmd.com/read/29064160/marijuana-commercialization-and-adolescent-substance-treatment-outcomes-in-colorado
#12
Sean R LeNoue, Stacy Salomonsen-Sautel, Sung-Joon Min, Christian Thurstone
BACKGROUND AND OBJECTIVES: In Colorado, marijuana was legalized for medical use in 2000, commercialized in 2009, and approved for recreational purposes in 2012. Little is known about the association between recent policy changes and adolescent substance treatment outcomes measured by urine drug screens (UDS). This study addressed this research gap. METHODS: Participants were youth (N = 523) aged 11-19 years who were enrolled in an outpatient motivational interviewing (MI)/cognitive behavioral therapy (CBT) plus contingency management (CM) in Denver, Colorado from October 2007 to June 2014...
October 24, 2017: American Journal on Addictions
https://www.readbyqxmd.com/read/29051478/genetic-accommodation-via-modified-endocrine-signalling-explains-phenotypic-divergence-among-spadefoot-toad-species
#13
Saurabh S Kulkarni, Robert J Denver, Ivan Gomez-Mestre, Daniel R Buchholz
Phenotypic differences among species may evolve through genetic accommodation, but mechanisms accounting for this process are poorly understood. Here we compare hormonal variation underlying differences in the timing of metamorphosis among three spadefoot toads with different larval periods and responsiveness to pond drying. We find that, in response to pond drying, Pelobates cultripes and Spea multiplicata accelerate metamorphosis, increase standard metabolic rate (SMR), and elevate whole-body content of thyroid hormone (the primary morphogen controlling metamorphosis) and corticosterone (a stress hormone acting synergistically with thyroid hormone to accelerate metamorphosis)...
October 19, 2017: Nature Communications
https://www.readbyqxmd.com/read/29048958/shade-sails-and-passive-recreation-in-public-parks-of-melbourne-and-denver-a-randomized-intervention
#14
RANDOMIZED CONTROLLED TRIAL
David B Buller, Dallas R English, Mary Klein Buller, Jody Simmons, James A Chamberlain, Melanie Wakefield, Suzanne Dobbinson
OBJECTIVES: To test whether shade sails will increase the use of passive recreation areas (PRAs). METHODS: We conducted a stratified randomized pretest-posttest controlled design study in Melbourne, Australia, and Denver, Colorado, in 2010 to 2014. We randomized a sample of 144 public parks with 2 PRAs in full sun in a 1:3 ratio to treatment or control. Shade sails were built at 1 PRA per treatment park. The outcome was any use of the study PRA (n = 576 pretest and n = 576 posttest observations; 100% follow-up)...
December 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/29038282/intracellular-tenofovir-diphosphate-and-emtricitabine-triphosphate-in-dried-blood-spots-following-directly-observed-therapy-the-dot-dbs-study
#15
Peter L Anderson, Albert Y Liu, Jose R Castillo-Mancilla, Edward M Gardner, Sharon M Seifert, Cricket McHugh, Theresa Wagner, Kayla Campbell, Mary Morrow, Mustafa Ibrahim, Susan Buchbinder, Lane R Bushman, Jennifer J Kiser, Samantha MaWhinney
Studies of daily emtricitabine-tenofovir disoproxil fumarate (FTC-TDF) for HIV pre-exposure prophylaxis (PrEP) in men who have sex with men (MSM) modeled intracellular tenofovir-diphosphate (TFV-DP) in dried blood spots (DBS) to assess adherence and corresponding PrEP outcomes. We conducted a prospective, randomized, cross-over pharmacokinetic study of TFV-DP in DBS during 33%, 67% or 100% of daily dosing, under directly observed therapy (DOT). Participants were assigned to two 12-week dosing regimens, separated by a 12-week washout...
October 16, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/29037527/cork-study-in-cystic-fibrosis-sustained-improvements-in-ultra-low-dose-chest-ct-scores-after-cftr-modulation-with-ivacaftor
#16
Nicola J Ronan, Gisli G Einarsson, Maria Twomey, Denver Mooney, David Mullane, Muireann NiChroinin, Grace O'Callaghan, Fergus Shanahan, Desmond M Murphy, Owen J O'Connor, Cathy A Shortt, Michael M Tunney, Joseph A Eustace, Michael M Maher, J Stuart Elborn, Barry J Plant
BACKGROUND: Ivacaftor produces significant clinical benefit in patients with cystic fibrosis (CF) with the G551D mutation. Prevalence of this mutation at the Cork CF Centre is 23%. This study assessed the impact of CFTR modulation on multiple modalities of patient assessment. METHODS: Thirty-three patients with the G551D mutation were assessed at baseline and prospectively every 3 months for 1 year after initiation of ivacaftor. Change in ultra-low-dose chest CT scans, blood inflammatory mediators, and the sputum microbiome were assessed...
October 14, 2017: Chest
https://www.readbyqxmd.com/read/29031827/development-of-a-surgical-site-infection-prediction-model-in-orthopaedic-trauma-the-denver-health-model
#17
Sara M Reese, Bryan Knepper, Heather L Young, Cyril Mauffrey
BACKGROUND: The CDC's National Healthcare Safety Network's (NHSN) current risk adjustment model for surgical site infections (SSI) following open reduction internal fixation (ORIF) of long bone fractures is a suboptimal predictor of risk. We hypothesized that by including variables known to be associated with SSI following ORIF, we would develop a model that would increase the accuracy and predictability of SSI risk. METHODS: Patients who underwent ORIF of a long bone between January 1, 2012 and December 31, 2014 were included in the study (n=1543)...
October 9, 2017: Injury
https://www.readbyqxmd.com/read/29031478/patterns-of-facial-trauma-before-and-after-legalization-of-marijuana-in-denver-colorado-a-joint-study-between-two-denver-hospitals
#18
Mofiyinfolu Sokoya, Justin Eagles, Tyler Okland, Dylan Coughlin, Hannah Dauber, Christopher Greenlee, Andrew A Winkler
INTRODUCTION: The effect of marijuana on human health has been studied extensively. Marijuana intoxication has been shown to affect performance, attention span, and reaction time. The public health relationship between trauma and cannabis use has also been studied, with mixed conclusions. In this report, the effect of marijuana legalization on many aspects of facial trauma at two hospitals in Denver, Colorado is examined. METHODS: A retrospective review of the electronic medical records was undertaken...
October 7, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29028367/philip-hillkowitz-the-granddaddy-of-medical-technologists-and-cofounder-of-the-american-society-for-clinical-pathologists-and-the-jewish-consumptives-relief-society
#19
James R Wright, Jeanne Abrams
CONTEXT: - In the early 20th century, the future of hospital-based clinical pathology practice was uncertain and this situation led to the formation of the American Society for Clinical Pathologists in 1922. Philip Hillkowitz and Ward Burdick were its cofounders. No biography of Hillkowitz exists. OBJECTIVE: - To explore the life, beliefs, and accomplishments of Philip Hillkowitz. DESIGN: - Available primary and secondary historical sources were reviewed...
October 13, 2017: Archives of Pathology & Laboratory Medicine
https://www.readbyqxmd.com/read/28981826/differences-in-the-density-of-fungiform-papillae-and-composition-of-saliva-in-patients-with-taste-disorders-compared-to-healthy-controls
#20
Ute Walliczek-Dworschak, Franz Schöps, Gilles Feron, Helene Brignot, Antje Hähner, Thomas Hummel
This study investigated the relation of the fungiform taste papillae density and saliva composition with the taste perception of patients suffering from diagnosed taste disorders. For this purpose, 81 patients and 40 healthy subjects were included. Taste was measured by means of regional and whole mouth chemosensory tests, and electrogustometry. Olfaction was assessed using the Sniffin Sticks. Fungiform papillae were quantified using the "Denver Papillae Protocol for Objective Analysis of Fungiform Papillae"...
October 1, 2017: Chemical Senses
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