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Pipeline OR flow diverter OR flow diverting OR flow divertion AND aneurysm

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https://www.readbyqxmd.com/read/28904796/endovascular-management-of-symptomatic-cerebral-aneurysm-thromboembolism-due-to-pre-aneurysmal-arterial-stenosis
#1
Torin Karsonovich, Ajeet Gordhan
BACKGROUND: Pre-aneurysmal internal carotid steno-occlusive disease resulting in cerebral intra-aneurysmal thrombosis and subsequent embolic infarction has not been previously described. CONCLUSION: Antithrombotic treatment for dissolution of the thrombus and pre-aneurysmal stent angioplasty followed by Pipeline embolization flow diverter placement through the aneurysm is a safe and feasible management option.
2017: SAGE open medical case reports
https://www.readbyqxmd.com/read/28891190/is-multiple-overlapping-uncovered-stents-technique-suitable-for-aortic-aneurysm-repair
#2
Siang Lin Yeow, Hwa Liang Leo
A computational fluid dynamic model to assess the impact of flow-diverter device on intra-aneurysmal flow in complex aortic aneurysm from the viewpoint of hemodynamics is presented. The aim of this study is to investigate the hemodynamic effects of an endovascular flow-diverter technique using multiple overlapping uncovered stents (MOUS) in the treatment of complex aortic aneurysm involving side branch. The placement of porous barrier such as MOUS across the aneurysm alters the blood flow pattern in the aneurysm sac...
September 11, 2017: Artificial Organs
https://www.readbyqxmd.com/read/28887074/paediatric-aneurysms-review-of-endovascular-treatment-strategies
#3
REVIEW
P Bhogal, M Aguilar Pérez, C Wendl, H Bäzner, O Ganslandt, H Henkes
Paediatric aneurysms are rare and represent the end result of a variety of different pathological mechanisms. They have a varied presentation and features that are distinct from their adult counterparts. The appropriate management of these aneurysms requires a multi-disciplinary team approach and detailed analysis to deal with the underlying pathology. This can involve the use of coils, adjunctive devices such as neck-bridging devices, flow diverters and liquid embolic agents, as well as microsurgical clipping...
September 5, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28875355/is-there-an-association-between-flow-diverter-fish-mouthing-and-delayed-type-hypersensitivity-to-metals-a-case-control-study
#4
Naci Kocer, Prabath Kumar Mondel, Elif Yamac, Ayse Kavak, Osman Kizilkilic, Civan Islak
PURPOSE: Flow diverters are increasingly used in the treatment of complex and giant intracranial aneurysms. However, they are associated with complications like late aneurysmal rupture. Additionally, flow diverters show focal structural decrease in luminal diameter without any intimal hyperplasia. This resembles a "fish mouth" when viewed en face. In this pilot study, we tested the hypothesis of a possible association between flow diverter fish-mouthing and delayed-type hypersensitivity to its metal constituents...
September 5, 2017: Neuroradiology
https://www.readbyqxmd.com/read/28860903/a-novel-flow-diverter-tubridge-for-the-treatment-of-recurrent-aneurysms-a-single-center-experience
#5
Yongxin Zhang, Qing-Hai Huang, Yibin Fang, Pengfei Yang, Yi Xu, Bo Hong, Jianmin Liu
OBJECTIVE: The Tubridge flow diverter (FD) is a novel device aimed at reconstructing the parent artery and occluding complex aneurysms. Retreatment of recurrent aneurysms using the FD is challenging. We report our initial experience in the repair of aneurysm recurrence with the FD. MATERIALS AND METHODS: A database was reviewed prospectively, and 8 patients with 8 recurrent aneurysms (mean size, 16.7 mm) were identified. Four aneurysms had previously ruptured. The previous aneurysm treatment consisted of coiling in 1 aneurysm and single-stent-assisted coiling in 7 aneurysms...
September 2017: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
https://www.readbyqxmd.com/read/28842742/in-vitro-contrast-agent-based-evaluation-of-the-influence-of-flow-diverter-size-and-position-on-intra-aneurysmal-flow-dynamics-using-syngo-iflow
#6
Giorgio Franco Maria Cattaneo, Andreas Ding, Tobias Jost, Désirée Ley, Ruben Mühl-Bennighaus, Umut Yilmaz, Heiko Körner, Wolfgang Reith, Andreas Simgen
PURPOSE: Treatment of intracranial aneurysm with flow-diverting devices has become widespread in recent years. Despite that, intra-aneurysmal flow changes are yet not fully understood and can lead to different complications. Our aim was an in vitro contrast-based evaluation of the influence of flow diverter size and position on intra-aneurysmal flow dynamics. METHODS: Flow-diverting devices with different sizes (diameters 4.0, 4.5, and 6.0 mm) were deployed in seven silicone aneurysm models at different positions relative to the aneurysm neck (proximal, central, distal)...
August 25, 2017: Neuroradiology
https://www.readbyqxmd.com/read/28839527/a-new-imaging-tool-for-realtime-measurement-of-flow-velocity-in-intracranial-aneurysms
#7
Athanasios K Petridis, Marius Kaschner, Jan F Cornelius, Marcel A Kamp, Angelo Tortora, Hans-Jakob Steiger, Bernd Turowski
With modern imaging modalities of the brain a significant number of unruptured aneurysms are detected. However, not every aneurysm is prone to rupture. Because treatment morbidity is about 10% it is crucial to identify unstable aneurysms for which treatment should be discussed. Recently, new imaging tools allow analysis of flow dynamics and wall stability have become available. It seems that they might provide additional data for better risk profiling. In this study we present a new imaging tool for analysis of flow dynamics, which calculates fluid velocity in an aneurysm (Phillips Electronics, N...
June 7, 2017: Clinics and Practice
https://www.readbyqxmd.com/read/28838114/endovascular-treatment-of-large-and-giant-carotid-aneurysms-with-flow-diverter-stents-alone-or-in-combination-with-coils-a-multicenter-experience-and-long-term-follow-up
#8
Simone Peschillo, Alessandro Caporlingua, Maria Chiara Resta, Jo Peter Paul Peluso, Nicola Burdi, Nader Sourour, Francesco Diana, Giulio Guidetti, Frédéric Clarençon, Gijs Coenraad Bloemsma, Federico Di Maria, Massimo Donatelli, Maurizio Resta
BACKGROUND: Although flow diverters (FDs) have been widely accepted by neurointerventionists, their safety has yet to be fully defined. Stratification by aneurysm size and location is essential for correct evaluation of treatment outcomes and risks of flow diversion. OBJECTIVE: To compare neurological and anatomic outcomes and evaluate the risk of complications after endovascular treatment of large or giant internal carotid artery (ICA) aneurysms with FD/FDs alone or together with coil embolization...
August 1, 2017: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/28819696/what-are-the-treatment-options-for-blister-like-aneurysms
#9
REVIEW
Torstein R Meling
Treatment of blood blister-like aneurysms (BBAs) of the supraclinoidal internal carotid artery (ICA) is challenging and the optimal treatment is yet to be defined. The treatment options for ICA BBAS are microsurgery, endovascular therapy, or a combination of the two. The microsurgical armamentarium consists mainly of direct aneurysm clipping with or without protective EC-IC bypass, clip-wrapping, or trap ligation with ICA sacrifice with or without EC-IC bypass. The endovascular treatment options are mainly endovascular ICA ligation, multiple overlapping stents (≥ 3) with or without coiling, covered stents, or flow diverters...
August 17, 2017: Neurosurgical Review
https://www.readbyqxmd.com/read/28818824/clinical-impact-of-flat-panel-volume-ct-angiography-in-evaluating-the-accurate-intraoperative-deployment-of-flow-diverter-stents
#10
F Clarençon, F Di Maria, J Gabrieli, E Shotar, V Degos, A Nouet, A Biondi, N-A Sourour
BACKGROUND AND PURPOSE: The deployment of flow-diverter stents may be difficult to analyse on regular DSA. The purpose of our study was to investigate the clinical impact of stent-dedicated flat panel volume CT angiography to evaluate intraoperatively the satisfactory deployment of flow-diverter stents. MATERIALS AND METHODS: From January 2009 to April 2015, 83 consecutive patients (mean age, 51 years; 62 women) were treated in our institution with flow-diverter stents...
August 17, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/28808603/aneurysm-treatment-practice-patterns-for-newly-appointed-dual-trained-cerebrovascular-endovascular-neurosurgeons-comparison-of-open-surgical-to-neuroendovascular-procedures-in-the-first-2-years-of-academic-practice
#11
Bowen Jiang, Matthew T Bender, Bima Hasjim, Frank P K Hsu, Rafael J Tamargo, Judy Huang, Geoffrey P Colby, Alexander L Coon, Li-Mei Lin
BACKGROUND: The practice patterns of a hybrid open cerebrovascular/neuroendovascular (CVNV) neurosurgeon in early academic practice is unknown. METHODS: We performed a multi-institutional retrospective cohort study of patients with cerebral aneurysms that were treated within the first 24 months of the neurosurgeon's practice. RESULTS: A total of 533 aneurysms were treated by the three senior authors within the first 24 months of their academic practice...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/28798217/multicenter-experience-with-fred-jr-flow-re-direction-endoluminal-device-for-intracranial-aneurysms-in-small-arteries
#12
M A Möhlenbruch, O Kizilkilic, M Killer-Oberpfalzer, F Baltacioglu, C Islak, M Bendszus, S Cekirge, I Saatci, N Kocer
BACKGROUND AND PURPOSE: Flow diverters are emerging as an endovascular treatment alternative for proximally located intracranial aneurysms. However, treatment of aneurysms at and beyond the circle of Willis is not well-established. We assessed the clinical safety and efficacy of the Flow Re-Direction Endoluminal Device Jr (FRED Jr) dedicated to small-vessel diameters between 2.0 and 3.0 mm. MATERIALS AND METHODS: This was a multicenter observational clinical study of 42 patients with 47 aneurysms treated by a flow-direction technique with the FRED Jr...
August 10, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/28782689/flow-diverter-treatment-of-tandem-intracranial-aneurysms
#13
Seby John, Mark Bain, Russell Cerejo, Andrew Bauer, Thomas Masaryk, Muhammad S Hussain, Peter Rasmussen, Gabor Toth
OBJECTIVE: The application of flow diversion (FD) for treatment of multiple, tandem intracranial aneurysms has not been well studied. We sought to assess technical success, and clinical and imaging outcomes of FD treatment for tandem intracranial aneurysms. METHODS: Retrospective analysis of patients treated with FD for tandem intracranial aneurysms. RESULTS: Twenty female patients were included with a mean (± SD) age of 60 ±12 years. Only one patient was treated after subarachnoid hemorrhage...
August 3, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28765024/amd3100-accelerates-reendothelialization-of-neointima-in-rabbit-saccular-aneurysm-after-flow-diverter-treatment
#14
Zifu Li, Rui Zhao, Xinggen Fang, Jiahao Zhou, Guoquan Jiang, Qinghai Huang, Jianmin Liu
OBJECTIVE: To inspect the role of AMD3100 that acts as an antagonist of SDF-1/CXCR4 on the formation of neointima in rabbit saccular aneurysm after flow diverter (FD) treatment. METHODS: Twenty saccular aneurysm models were established by using porcine pancreatic elastase. Three weeks later, a FDs of Tubridge was implanted into the saccular aneurysm. All treated models were immediately divided into two groups: the AMD3100 group was subcutaneously injected with AMD3100 (5 mg/kg per day), while control group with saline...
July 29, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28758550/treatment-of-ruptured-blood-blister-aneurysms-using-primary-flow-diverter-stenting-with-considerations-for-adjunctive-coiling-a-single-centre-experience-and-literature-review
#15
Cunli Yang, Agnes Vadasz, István Szikora
Objective The objective of this article is to conduct a single-centre evaluation and quick literature review of the effectiveness of primary flow-diverter (FD) treatment of ruptured blood blister aneurysms (BBAs), with additional relevance of adjunctive coiling. Methods Patients presenting with subarachnoid haemorrhage (SAH) due to ruptured BBAs and subsequently treated with FDs were retrospectively selected from June 2010 to January 2017. Treatment techniques, angiographic data on occlusion rates and procedural success as well as clinical outcomes using the modified Rankin Scale (mRS) were collated...
January 1, 2017: Interventional Neuroradiology
https://www.readbyqxmd.com/read/28754807/balloon-assisted-coil-embolization-and-large-stent-delivery-for-cerebral-aneurysms-with-a-new-generation-of-dual-lumen-balloons-copernic-2l
#16
Adrien Guenego, Jean-Baptiste Zerlauth, Francesco Puccinelli, Steven Hajdu, David C Rotzinger, Felix Zibold, Eike I Piechowiak, Pasquale Mordasini, Jan Gralla, Tomas Dobrocky, Roy T Daniel, René Chapot, Pascal J Mosimann
INTRODUCTION: Dual coaxial lumen balloon microcatheters through which small stents can be delivered have recently been described. We report a series of a new type of dual lumen balloon catheter with a parallel lumen design enabling enhanced inflation and deflation properties through which larger stents may be deployed, including flow diverters (FD). METHODS: All aneurysms that were treated with a Copernic 2L (COP2L) dual lumen balloon catheter at our institution between February 2014 and December 2016 were assessed...
July 28, 2017: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/28748748/outcome-study-of-the-pipeline-embolization-device-for-treatment-of-intracranial-aneurysms-at-a-single-uk-institution
#17
Shih-Hung Yang, Timothy Hampton, Naga Kandasamy, Jonathan Hart, Jonathan Ashmore, Daniel C Walsh, Christos M Tolias, Thomas C Booth
BACKGROUND: The introduction of flow-diverting stents in the last decade provides an alternative endovascular treatment choice in selected intracranial aneurysms. This retrospective analysis of a UK centre's experience provides insight into clinical and radiographic outcomes. METHODS: Electronic patient records, diagnostic and procedural images and written procedural records for patients treated with the PED between August 2009 and April 2014 were reviewed. Follow-up TOF MRA was performed after treatment...
July 27, 2017: British Journal of Neurosurgery
https://www.readbyqxmd.com/read/28689955/flow-diverting-stent-in-the-treatment-of-cervical-carotid-dissection-and-pseudoaneurysm-review-of-literature-and-case-report
#18
REVIEW
Anna Paula Weinhardt Baptista-Sincos, Aline Bigatão Simplício, Igor Rafael Sincos, Alex Leaderman, Fernando Saliture Neto, Adjaldes Moraes, Ricardo Aun
BACKGROUND: The endovascular technique has been recommended over the past few years to extracranial carotid dissection and pseudoaneurysm with promising results, especially after medical therapy failure. Flow-diverting stents are an alternative for complex cases. These stents have proven to be effective treatment devices for intracranial aneurysms. METHODS: The reference list of Pham's systematic review, published in 2011, and Seward's literature review, published in 2015, was considered, as well as all new articles with eligible features...
July 6, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28689183/acute-thrombus-formation-on-phosphorilcholine-surface-modified-flow-diverters
#19
Miklos Marosfoi, Frederic Clarencon, Erin T Langan, Robert M King, Olivia W Brooks, Takamisu Tamura, John M Wainwright, Matthew J Gounis, Srinivasan Vedantham, Ajit S Puri
PURPOSE: Thromboembolic complications remain a limitation of flow diverting stents. We hypothesize that phosphorilcholine surface modified flow diverters (Pipeline Flex with Shield Technology, sPED) would have less acute thrombus formation on the device surface compared with the classic Pipeline Embolization device (cPED). METHODS: Elastase-induced aneurysms were created in 40 rabbits and randomly assigned to receive cPED or sPED devices with and without dual antiplatelet therapy (DAPT) (four groups, n=10/group)...
July 8, 2017: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/28685380/intracranial-aneurysms-treated-by-flow-diverting-stents-long-term-follow-up-with-contrast-enhanced-magnetic-resonance-angiography
#20
Maximilian Patzig, Robert Forbrig, Lorenz Ertl, Hartmut Brückmann, Gunther Fesl
PURPOSE: Long-term data on aneurysm treatment with flow-diverting stents are still sparse, and follow-up protocols differ widely between institutions. We present long-term results, with a focus on the usefulness of contrast-enhanced MR angiography (ceMRA). MATERIALS AND METHODS: Interventions and follow-up imaging of patients with aneurysms treated by flow-diverting stents ("Pipeline," "Silk" and "FRED" models) without additional coiling were analyzed. All MRI scans included dedicated two-phase ceMRA...
July 6, 2017: Cardiovascular and Interventional Radiology
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