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Pipeline OR flow diverter OR flow diverting OR flow divertion AND aneurysm

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https://www.readbyqxmd.com/read/29140523/sequential-coiling-assisted-deployment-of-flow-diverter-for-treatment-of-fusiform-middle-cerebral-artery-aneurysms
#1
Abdulrahman Y Alturki, Philip G R Schmalz, Christopher S Ogilvy, Ajith J Thomas
BACKGROUND AND IMPORTANCE: Fusiform intracranial aneurysms remain challenging lesions to treat. These aneurysms have historically required bypass procedures or clip remodeling constructs for cure. Recently, endovascular specialists have reported experience with flow diversion for complex fusiform aneurysms of the vertebrobasilar system, with mixed results. Vascular anatomy for anterior circulation fusiform aneurysms may make these lesions more amenable to flow diversion and embolization procedures; however, published experience with these techniques is lacking...
November 11, 2017: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29127197/communicating-malapposition-of-flow-diverters-assessed-with-optical-coherence-tomography-correlates-with-delayed-aneurysm-occlusion
#2
Robert M King, Olivia W Brooks, Erin T Langan, Jildaz Caroff, Frédéric Clarençon, Takamitsu Tamura, John Michael Wainwright, Matthew J Gounis, Miklós Marosfői, Ajit S Puri
BACKGROUND: Optical coherence tomography (OCT) is a high resolution intravascular imaging method that allows visualization of flow diverter struts and the vessel wall. In this study, malapposition of the flow diverter that continues into the neck of the aneurysm, named communicating malapposition (CM), was investigated as a potential factor for delayed aneurysm healing. METHODS: 40 New Zealand White rabbits underwent elastase induced aneurysm creation, and were subsequently assigned to one of four treatment groups based on flow diverter type and administration of antiplatelet therapy...
November 10, 2017: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/29125410/hemorrhage-associated-with-ventriculoperitoneal-shunt-placement-in-aneurysmal-subarachnoid-hemorrhage-patients-on-a-regimen-of-dual-antiplatelet-therapy-a-retrospective-analysis
#3
Joseph S Hudson, Yasunori Nagahama, Daichi Nakagawa, Robert M Starke, Brian J Dlouhy, James C Torner, Pascal Jabbour, Lauren Allan, Colin P Derdeyn, Jeremy D W Greenlee, David Hasan
OBJECTIVE Intracranial stenting and flow diversion require the use of dual antiplatelet therapy (DAPT) to prevent in-stent thrombosis. DAPT may significantly increase the risk of hemorrhagic complications in patients who require subsequent surgical interventions. In this study, the authors sought to investigate whether DAPT is a risk factor for hemorrhagic complications associated with ventriculoperitoneal (VP) shunt placement in patients with aneurysmal subarachnoid hemorrhage (aSAH). Moreover, the authors sought to compare VP shunt complication rates with respect to the shunt's location from the initial external ventricular drain (EVD) site...
November 10, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29118794/safety-and-efficacy-of-low-profile-self-expandable-stents-for-treatment-of-intracranial-aneurysms-initial-and-midterm-results-a-systematic-review-and-meta-analysis
#4
Su-Yeon Park, Jae-Sang Oh, Hyuk-Jin Oh, Seok-Mann Yoon, Hack-Gun Bae
Low-profile stents seem to be associated with a higher incidence of thromboembolic events compared with preexisting stents. We conducted a systematic review of 11 eligible reports and a meta-analysis of 7 reports with respect to the clinical efficacy and safety of low-profile stents. There were 217 intracranial aneurysms reported; 22% were ruptured aneurysms. In all, 72% were treated using single stenting, 19% were treated using overlapping stenting, and 6% were treated using balloon angioplasty followed by stenting; 3% were used to assess the flow diverter effect in a dissecting aneurysm or were treated using unexpected subtotal coil packing...
October 2017: Interventional Neurology
https://www.readbyqxmd.com/read/29099296/dual-antiplatelet-therapy-in-aneurysmal-subarachnoid-hemorrhage-association-with-reduced-risk-of-clinical-vasospasm-and-delayed-cerebral-ischemia
#5
Yasunori Nagahama, Lauren Allan, Daichi Nakagawa, Mario Zanaty, Robert M Starke, Nohra Chalouhi, Pascal Jabbour, Robert D Brown, Colin P Derdeyn, Enrique C Leira, Joseph Broderick, Marc Chimowitz, James C Torner, David Hasan
OBJECTIVE Clinical vasospasm and delayed cerebral ischemia (DCI) are devastating complications of aneurysmal subarachnoid hemorrhage (aSAH). Several theories involving platelet activation have been postulated as potential explanations of the development of clinical vasospasm and DCI. However, the effects of dual antiplatelet therapy (DAPT; aspirin and clopidogrel) on clinical vasospasm and DCI have not been previously investigated. The objective of this study was to evaluate the effects of DAPT on clinical vasospasm and DCI in aSAH patients...
November 3, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29060624/sensitivity-study-on-modelling-a-flow-diverting-stent-as-a-porous-medium-using-computational-fluid-dynamics
#6
Yujie Li, Mingzi Zhang, David I Verrelli, William Yang, Winston Chong, Makoto Ohta, Yi Qian
The flow-diverting (FD) stent has become a commonly used endovascular device to treat cerebral aneurysms. This discourages blood from entering the aneurysm, thereby reducing the likelihood of aneurysm rupture. Using computational fluid dynamics (CFD) to simulate the aneurysmal haemodynamics after FD treatment could help clinicians predict the stent effectiveness prior to the real procedure in the patient. As an alternative to modelling the stent as a fine wire mesh, modelling the FD stent as a porous medium was established to save computational time, and has also been proved capable of predicting the same haemodynamics as obtained using the real FD stent geometry...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29054914/flow-diversion-for-the-treatment-of-posterior-inferior-cerebellar-artery-aneurysms-a-novel-classification-and-strategies
#7
Visish M Srinivasan, Michael George Zaki Ghali, Oleg E Reznik, Jacob Cherian, Maxim Mokin, Travis M Dumont, John R Gaughen, Ramesh Grandhi, Ajit S Puri, Stephen R Chen, Jeremiah N Johnson, Peter Kan
BACKGROUND: The pipeline embolization device (PED) is frequently used in the treatment of anterior circulation aneurysms, especially around the carotid siphon, with generally excellent results. However, treatment of posterior inferior cerebellar artery (PICA) aneurysms with flow diversion (FD) has not been specifically described or discussed. While there are reports of treating PICA aneurysms using placement of FD stents in the vertebral artery, there are no reports of treating these lesions by placement of flow diverting stents in the PICA vessel itself...
October 20, 2017: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/29046918/flow-diverter-treatment-of-cerebral-blister-aneurysms
#8
Russell Cerejo, Mark Bain, Seby John, Julian Hardman, Nina Moore, M Shazam Hussain, Gabor Toth
PURPOSE: Blood blister-like aneurysms (BBA) are small, friable, broad-based aneurysms that represent high risk for rerupture. Treatment of BBA is challenging, and may include surgical wrapping, clipping, multiple overlapping stents, and/or coiling. Flow diversion is a rapidly evolving treatment strategy for intracranial aneurysms, but the evidence for its use in cases of BBA is scarce. METHODS: A retrospective review of flow-diverter-treated, ruptured BBA cases at our tertiary care institution was undertaken...
October 18, 2017: Neuroradiology
https://www.readbyqxmd.com/read/28994804/biodegradable-magnesium-stent-treatment-of-saccular-aneurysms-in-a-rat-model-introduction-of-the-surgical-technique
#9
Edin Nevzati, Jeannine Rey, Daniel Coluccia, Donato D'Alonzo, Basil Grüter, Luca Remonda, Javier Fandino, Serge Marbacher
The steady progess in the armamentarium of techniques available for endovascular treatment of intracranial aneurysms requires affordable and reproducable experimental animal models to test novel embolization materials such as stents and flow diverters. The aim of the present project was to design a safe, fast, and standardized surgical technique for stent assisted embolization of saccular aneurysms in a rat animal model. Saccular aneurysms were created from an arterial graft from the descending aorta.The aneurysms were microsurgically transplanted through end-to-side anastomosis to the infrarenal abdominal aorta of a syngenic male Wistar rat weighing >500 g...
October 1, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28992722/the-treatment-of-pseudoaneurysms-with-flow-diverters-after-malignant-otitis-externa
#10
Tamás Németh, László Szakács, Zsolt Bella, Valéria Majoros, Pál Barzó, Erika Vörös
Background We report a case of bilateral malignant otitis externa complicated with bilateral petrous internal carotid artery pseudoaneurysms and their successful treatment with a flow diverter. Case report A 68-year-old woman with serious complications of type II diabetes mellitus had malignant otitis externa on the right side. She was treated with combined antibiotic therapy and underwent mastoidectomy for mastoiditis. She presented at our hospital with acute hemorrhage from the right external auditory canal...
December 2017: Interventional Neuroradiology
https://www.readbyqxmd.com/read/28982785/treatment-of-middle-cerebral-artery-aneurysms-with-flow-diverter-stents-a-systematic-review-and-meta-analysis
#11
F Cagnazzo, D Mantilla, P-H Lefevre, C Dargazanli, G Gascou, V Costalat
BACKGROUND: The safety and efficacy of flow-diversion treatment of MCA aneurysms have not been well-established. PURPOSE: Our aim was to evaluate angiographic and clinical outcomes after flow diversions for MCA aneurysms. DATA SOURCES: A systematic search of PubMed, MEDLINE, and Embase was performed for studies published from 2008 to May 2017. STUDY SELECTION: According to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, we selected studies with >5 patients describing angiographic and clinical outcomes after flow-diversion treatment of MCA aneurysms...
October 5, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/28965108/meta-analysis-of-treatment-outcomes-of-posterior-circulation-non-saccular-aneurysms-by-flow-diverters
#12
Satoshi Kiyofuji, Christopher S Graffeo, Avital Perry, Mohammad Hassan Murad, Kelly D Flemming, Giuseppe Lanzino, Leonardo Rangel-Castilla, Waleed Brinjikji
INTRODUCTION: Non-saccular aneurysms of the posterior circulation are uncommon but highly dangerous lesions. Flow diverter stents have been demonstrated to be effective treatments of various anterior circulation aneurysms, particularly large and giant proximal internal carotid artery aneurysms. However, evidence regarding the treatment of non-saccular posterior circulation aneurysms with flow diverters is lacking. METHODS: A systematic literature review of the English language literature since 2007 was conducted using PubMed, MEDLINE, and Embase...
September 30, 2017: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/28962011/treatment-of-dissecting-distal-vertebral-artery-v4-aneurysms-with-flow-diverters
#13
Jacquelyn A Corley, Ali Zomorodi, L Fernando Gonzalez
BACKGROUND: Dissecting aneurysms of the intracranial vertebral arteries are rare; however, treatment of these presents multiple challenges, including high risk of rebleeding, development of thromboembolic strokes, and progressive partial thrombosis. Flow diverters, such as Pipeline Endovascular Devices (PEDs; Covidien, Medtronic Inc, Dublin, Ireland), have emerged as a potential treatment option. OBJECTIVE: To present our experience with patients treated at our institution with PEDs for dissecting distal vertebral artery (V4 segment) aneurysms...
August 9, 2017: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/28961750/flow-diverting-stents-for-the-obliteration-of-symptomatic-infectious-cavernous-carotid-artery-aneurysms
#14
Andrew Joshua Kobets, Aleka Scoco, Jonathan Nakhla, Allan Leonard Brook, Merritt Drew Kinon, Nrupen Baxi, David Altschul
BACKGROUND: Intracavernous aneurysms constitute up to 9% of all intracranial aneurysms and 6% are infectious (IIA). First line therapy is a protracted antibiotic course, yet with failure, surgery and endovascular parent vessel sacrifice have been utilized. Reconstructive endovascular therapies have emerged for aneurysm control and may demonstrate a safer therapeutic alternative. OBJECTIVE: To present an IIA treated with a flow-diverting Pipeline stent (ev3 Neurovascular, Irvine, California)...
August 5, 2017: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/28956513/the-medina-embolic-device-karolinska-experience
#15
P Bhogal, P A Brouwer, L Yeo, M Svensson, M Söderman
Background The aim of this study was to report our single centre experience with the Medina Embolic Device (MED). Methods We performed a retrospective analysis of prospectively collected data to identify all patients treated with the MED. A total of 14 aneurysms (non-consecutive), in 13 patients, were treated including one ruptured and one partially thrombosed aneurysm. Fundus diameter was ≥5 mm in all cases. We evaluated the angiographic appearances, the clinical status, complications, and the need for adjunctive devices or repeat treatments...
January 1, 2017: Interventional Neuroradiology
https://www.readbyqxmd.com/read/28955510/usefulness-of-the-pipeline-embolic-device-for-large-and-giant-carotid-cavernous-aneurysms
#16
Shigeru Miyachi, Ryo Hiramatsu, Hiroyuki Ohnishi, Ryokichi Yagi, Toshihiko Kuroiwa
PURPOSE: Conventional coil embolization for large carotid cavernous aneurysms (CCAs) has limited utility due to its inability to prevent recurrences and reduce mass effect. Trapping of the parent artery may have a risk of ischemic complications due to intracranial perfusion disorders. We successfully treated 24 patients with large CCAs using a flow diverter (Pipeline™ embolic device: PED), and this report discusses the safety and efficacy of this method. MATERIALS AND METHODS: Twenty four patients (23 females, mean age 71...
September 2017: Neurointervention
https://www.readbyqxmd.com/read/28944944/endovascular-treatment-of-intracranial-anterior-circulation-aneurysms-with-flow-diverters-a-single-centre-experience-with-mid-and-long-term-results
#17
Ezel Yaltirik Bilgin, Baran Önal, Hakan Emmez, Koray Akkan, Erhan Ilgit, Erkan Bilgin, Emetullah Cindil, Alp Ozgun Borcek
AIM: We report our experience with flow diverter devices in the treatment of intracranial aneurysms arising from anterior circulation with mid and long-term follow-up. MATERIAL AND METHODS: 78 aneurysms in 61 patients (range 25-81 years, 13 male, 48 female) were treated with flow diverter devices. 40 (51,3%) aneurysms were treated with pipeline embolization device (PED), 24 (30,8%) aneurysms were treated with SILK stent, 12(15,4%) aneurysms were treated with flow redirection endoluminal device (FRED) and two aneurysms were treated with P64 Flow Modulation Device (P64)...
July 11, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28933202/giant-vertebrobasilar-aneurysm-a-rare-cause-of-central-sleep-apnoea
#18
Mark Daniel Haley, Duncan Bruce Henry Henderson, Mark Nowell, William M Adams, Peter C Whitfield
We report a case of central sleep apnoea (CSA) due to a giant vertebrobasilar aneurysm with brainstem compression. A flow diverter stent was deployed with coil embolization of the right vertebral artery distal to the posterior inferior cerebellar artery (PICA) to occlude the aneurysm. The patient's symptoms improved following therapy.
September 21, 2017: British Journal of Neurosurgery
https://www.readbyqxmd.com/read/28904796/endovascular-management-of-symptomatic-cerebral-aneurysm-thromboembolism-due-to-pre-aneurysmal-arterial-stenosis
#19
Torin Karsonovich, Ajeet Gordhan
BACKGROUND: Pre-aneurysmal internal carotid steno-occlusive disease resulting in cerebral intra-aneurysmal thrombosis and subsequent embolic infarction has not been previously described. CONCLUSION: Antithrombotic treatment for dissolution of the thrombus and pre-aneurysmal stent angioplasty followed by Pipeline embolization flow diverter placement through the aneurysm is a safe and feasible management option.
2017: SAGE open medical case reports
https://www.readbyqxmd.com/read/28891190/is-multiple-overlapping-uncovered-stents-technique-suitable-for-aortic-aneurysm-repair
#20
Siang Lin Yeow, Hwa Liang Leo
A computational fluid dynamic model to assess the impact of flow-diverter device on intra-aneurysmal flow in complex aortic aneurysm from the viewpoint of hemodynamics is presented. The aim of this study is to investigate the hemodynamic effects of an endovascular flow-diverter technique using multiple overlapping uncovered stents (MOUS) in the treatment of complex aortic aneurysm involving side branch. The placement of porous barrier such as MOUS across the aneurysm alters the blood flow pattern in the aneurysm sac...
September 11, 2017: Artificial Organs
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