keyword
MENU ▼
Read by QxMD icon Read
search

Alcohol, Drugs,

keyword
https://www.readbyqxmd.com/read/28220762/drug-detection-in-breath-non-invasive-assessment-of-illicit-or-pharmaceutical-drugs
#1
Phillip Trefz, Svend Kamysek, Patricia Fuchs, Pritam Sukul, Jochen Schubert, Wolfram Miekisch
Breath analysis not only holds great potential for the development of new non-invasive diagnostic methods, but also for the identification and follow up of drug levels in breath. This is of interest for both, forensic and medical science. On the one hand, the detection of drugs of abuse in exhaled breath - similar to the well-known breath alcohol tests - would be highly desirable as an alternative to blood or urine analysis in situations such as police controls for drugged driving. The noninvasive detection of drugs and their metabolites is thus of great interest in forensic science, especially since marijuana is becoming legalized in certain parts of the U...
February 21, 2017: Journal of Breath Research
https://www.readbyqxmd.com/read/28220511/review-article-pharmacotherapy-for-alcohol-dependence-the-why-the-what-and-the-wherefore
#2
REVIEW
E T Goh, M Y Morgan
BACKGROUND: The development of alcohol dependence is associated with significant morbidity and mortality. For the majority of affected people the most appropriate goal, in terms of drinking behaviour, is abstinence from alcohol. Psychosocial intervention is the mainstay of the treatment but adjuvant pharmacotherapy is also available and its use recommended. AIM: To provide an updated analysis of current and potential pharmacotherapeutic options for the management of alcohol dependence...
February 20, 2017: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/28219965/a-public-health-response-to-opioid-use-in-pregnancy
#3
Stephen W Patrick, Davida M Schiff
The use of opioids during pregnancy has grown rapidly in the past decade. As opioid use during pregnancy increased, so did complications from their use, including neonatal abstinence syndrome. Several state governments responded to this increase by prosecuting and incarcerating pregnant women with substance use disorders; however, this approach has no proven benefits for maternal or infant health and may lead to avoidance of prenatal care and a decreased willingness to engage in substance use disorder treatment programs...
February 20, 2017: Pediatrics
https://www.readbyqxmd.com/read/28219783/are-we-reducing-the-risk-of-cardiovascular-disease-and-improving-the-quality-of-life-through-preventive-health-care-results-of-a-population-based-study-in-south-australia
#4
David Alejandro González-Chica, Eleonora Dal Grande, Jacqueline Bowden, Michael Musker, Phillipa Hay, Nigel Stocks
This study investigated the achievement of lifestyle recommendations and use of preventive medication in people who 1) are obese, 2) or have metabolic risk factors (hypertension, dyslipidaemia, and/or diabetes), 3) or have cardiovascular disease (CVD), 4) or are healthy, and the impact this preventive health care had on their 'Health-Related Quality of Life' (HRQoL). Cross-sectional survey conducted in 2015 with 2379 South Australian adults (57.1±14years; 51.7% females). Physical (PCS) and mental components scores (MCS) of HRQoL were assessed using the SF-12 questionnaire...
February 17, 2017: Preventive Medicine
https://www.readbyqxmd.com/read/28218773/risk-factors-for-birth-defects
#5
Benjamin S Harris, Katherine C Bishop, Hanna R Kemeny, Jennifer S Walker, Eleanor Rhee, Jeffrey A Kuller
Importance: Major congenital abnormalities, or birth defects, carry significant medical, surgical, cosmetic, or lifestyle consequences. Such abnormalities may be syndromic, involving multiple organ systems, or can be isolated. Overall, 2% to 4% of live births involve congenital abnormalities. Risk factors for birth defects are categorized as modifiable and nonmodifiable. Modifiable risk factors require thorough patient education/counseling. The strongest risk factors, such as age, family history, and a previously affected child, are usually nonmodifiable...
February 2017: Obstetrical & Gynecological Survey
https://www.readbyqxmd.com/read/28217874/fabricating-triple-sensitive-polymer-nano-aggregates-via-an-aqueous-iminoboronate-multicomponent-reaction
#6
Yanning Liu, Guo Li, Jiangang Chen, Zhaotie Liu, Zhongwen Liu, Jinqiang Jiang
A triple-sensitive polymer of poly(ethylene glycol)-iminoboronate nitrobenzyl ethanediol chelate (PEG-INEC) is efficiently fabricated via the convenient aqueous iminoboronate multi-component reaction (MCR) of methoxypolyethylene glycol amine (mPEG-NH2 ), 2-formylphenylboronic acid (FPBA), and bis(2-nitrophenyl) ethanediol (BNPE, a photo-cleavable nitrobenzyl alcohol derivate). The aqueous MCR synthetic procedure is followed using (1) H NMR and turbidity analysis. It is shown that polymer nano-aggregates of PEG-INEC in aqueous solution can be dissociated through the stimuli responsive reactions of the hydrophobic iminoboronate nitrobenzyl ethanediol chelates (INECs) when exposed to UV light, acid, and H2 O2 , respectively...
February 20, 2017: Macromolecular Rapid Communications
https://www.readbyqxmd.com/read/28217830/relationship-between-alcohol-metabolism-and-chemotherapy-induced-emetic-events-in-breast-cancer-patients
#7
Toshitaka Uomori, Yoshiya Horimoto, Kaoru Mogushi, Joe Matsuoka, Mitsue Saito
BACKGROUND: Chemotherapy-induced nausea and vomiting (CINV) can negatively affect quality of life and treatment compliance in breast cancer patients. Habitual alcohol consumption reportedly shows an inverse correlation with CINV, though the underlying mechanism is unknown. Acetaldehyde dehydrogenase 2 (ALDH2), one of the two ALDH isozymes, is reportedly the major factor among several genetic polymorphisms possibly affecting alcohol metabolism. More than 40% of Japanese have ALDH2 mutations, while almost all Westerners have the wild type...
February 20, 2017: Breast Cancer: the Journal of the Japanese Breast Cancer Society
https://www.readbyqxmd.com/read/28216980/long-term-prognosis-in-patients-continuing-taking-antithrombotics-after-peptic-ulcer-bleeding
#8
Xi-Xu Wang, Bo Dong, Biao Hong, Yi-Qun Gong, Wei Wang, Jue Wang, Zhen-Yu Zhou, Wei-Jun Jiang
AIM: To investigate the long-term prognosis in peptic ulcer patients continuing taking antithrombotics after ulcer bleeding, and to determine the risk factors that influence the prognosis. METHODS: All clinical data of peptic ulcer patients treated from January 1, 2009 to January 1, 2014 were retrospectively collected and analyzed. Patients were divided into either a continuing group to continue taking antithrombotic drugs after ulcer bleeding or a discontinuing group to discontinue antithrombotic drugs...
January 28, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28216468/enhanced-ocular-efficacy-of-topically-delivered-dorzolamide-with-nanostructured-mucoadhesive-microparticles
#9
Chun Gwon Park, Young Kook Kim, Se-Na Kim, Seung Ho Lee, Beom Kang Huh, Min-A Park, Hyein Won, Ki Ho Park, Young Bin Choy
Dorzolamide eye drops are widely prescribed to reduce intraocular pressure (IOP) in the treatment of ocular hypertension and glaucoma. However, in an eye drop formulation, dorzolamide is rapidly cleared from the preocular space, hence requiring multiple daily administrations. Here, we sought to increase the preocular retention of dorzolamide using nanostructured, mucoadhesive microparticles (MUCO_NM) as carriers for topical delivery to the eye. MUCO_NM were prepared by freeze-milling dorzolamide-loaded, electrospun nanofibers composed of poly(lactic-co-glycolic acid) and polyethylene glycol...
February 16, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28216197/older-adults-who-use-or-have-used-marijuana-help-seeking-for-marijuana-and-other-substance-use-problems
#10
Namkee G Choi, Diana M DiNitto, C Nathan Marti
OBJECTIVE: Increasing numbers of older adults are using marijuana and may experience problems related to marijuana use. This study examined relationships (1) between help-seeking for marijuana use and the presence of other substance use and/or mental disorders and (2) between help-seeking for other substance use disorders and marijuana use among adults aged 50+. METHODS: The 2012-2013 National Epidemiologic Survey on Alcohol and Related Conditions provided data (N=14...
February 16, 2017: Journal of Substance Abuse Treatment
https://www.readbyqxmd.com/read/28216068/stages-of-dysfunctional-decision-making-in-addiction
#11
REVIEW
Antonio Verdejo-Garcia, Trevor T-J Chong, Julie C Stout, Murat Yücel, Edythe D London
Drug use is a choice with immediate positive outcomes, but long-term negative consequences. Thus, the repeated use of drugs in the face of negative consequences suggests dysfunction in the cognitive mechanisms underpinning decision-making. This cognitive dysfunction can be mapped into three stages: the formation of preferences involving valuation of decision options; choice implementation including motivation, self-regulation and inhibitory processes; and feedback processing implicating reinforcement learning...
February 16, 2017: Pharmacology, Biochemistry, and Behavior
https://www.readbyqxmd.com/read/28215999/rat-animal-models-for-screening-medications-to-treat-alcohol-use-disorders
#12
REVIEW
Richard L Bell, Sheketha R Hauser, Tiebing Liang, Youssef Sari, Antoinette Maldonado-Devincci, Zachary A Rodd
The purpose of this review is to present animal research models that can be used to screen and/or repurpose medications for the treatment of alcohol abuse and dependence. The focus will be on rats and in particular selectively bred rats. Brief introductions discuss various aspects of the clinical picture, which provide characteristics of individuals with alcohol use disorders (AUDs) to model in animals. Following this, multiple selectively bred rat lines will be described and evaluated in the context of animal models used to screen medications to treat AUDs...
February 16, 2017: Neuropharmacology
https://www.readbyqxmd.com/read/28215580/deviant-peers-as-a-mediator-of-pubertal-timing-substance-use-associations-the-moderating-role-of-parental-knowledge
#13
Kristine Marceau, Kristina Jackson
PURPOSE: Early perceived pubertal timing and faster maturation have been linked to increased risk of adolescent substance use (SU), particularly for girls, but the mechanisms underlying this association are not well understood. We sought to replicate and extend findings from Westling et al. (2008) showing that peer deviance mediates the link between early puberty and SU with stronger pathways in the context of low parental knowledge of adolescents' whereabouts and activities. METHODS: Participants (n = 1,023; 52% female, 24% nonwhite, and 12% Hispanic) were recruited through middle schools...
February 15, 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/28215192/music-genre-as-a-predictor-of-resource-utilization-at-outdoor-music-concerts
#14
Michael S Westrol, Susmith Koneru, Norah McIntyre, Andrew T Caruso, Faizan H Arshad, Mark A Merlin
OBJECTIVES: The aim of this study was to examine the various modern music genres and their effect on the utilization of medical resources with analysis and adjustment for potential confounders. METHODS: A retrospective review of patient logs from an open-air, contemporary amphitheater over a period of 10 years was performed. Variables recorded by the medical personnel for each concert included the attendance, description of the weather, and a patient log in which nature and outcome were recorded...
February 20, 2017: Prehospital and Disaster Medicine
https://www.readbyqxmd.com/read/28214742/what-s-the-agreement-between-self-reported-and-biochemical-verification-of-drug-use-a-look-at-permanent-supportive-housing-residents
#15
Alexis Rendon, Melvin Livingston, Sumihiro Suzuki, Whitney Hill, Scott Walters
Self-reported substance use is commonly used as an outcome measure in treatment research. We evaluated the validity of self-reported drug use in a sample of 334 adults with mental health problems who were residing in supportive housing programs. The primary analysis was the calculation of the positive predictive values (PPVs) of self-report compared to an oral fluid test taken at the same time. A sensitivity analysis compared the positive predictive values of two self-reported drug use histories: biological testing window (ranging between the past 96h to 30days depending on drug type) or the full past 90-day comparison window (maximum length recorded during interview)...
February 10, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/28214667/effects-of-prior-testing-lasting-a-full-year-in-ncanda-adolescents-contributions-from-age-sex-socioeconomic-status-ethnicity-site-family-history-of-alcohol-or-drug-abuse-and-baseline-performance
#16
Edith V Sullivan, Ty Brumback, Susan F Tapert, Devin Prouty, Rosemary Fama, Wesley K Thompson, Sandra A Brown, Kevin Cummins, Ian M Colrain, Fiona C Baker, Duncan B Clark, Tammy Chung, Michael D De Bellis, Stephen R Hooper, Bonnie J Nagel, B Nolan Nichols, Weiwei Chu, Dongjin Kwon, Kilian M Pohl, Adolf Pfefferbaum
Longitudinal study provides a robust method for tracking developmental trajectories. Yet inherent problems of retesting pose challenges in distinguishing biological developmental change from prior testing experience. We examined factors potentially influencing change scores on 16 neuropsychological test composites over 1year in 568 adolescents in the National Consortium on Alcohol and NeuroDevelopment in Adolescence (NCANDA) project. The twice-minus-once-tested method revealed that performance gain was mainly attributable to testing experience (practice) with little contribution from predicted developmental effects...
January 24, 2017: Developmental Cognitive Neuroscience
https://www.readbyqxmd.com/read/28214449/-they-treated-me-like-crap-and-i-know-it-was-because-i-was-native-the-healthcare-experiences-of-aboriginal-peoples-living-in-vancouver-s-inner-city
#17
Ashley Goodman, Kim Fleming, Nicole Markwick, Tracey Morrison, Louise Lagimodiere, Thomas Kerr
There is growing evidence that Aboriginal peoples often experience healthcare inequalities due to racism. However, research exploring the healthcare experiences of Aboriginal peoples who use illicit substances is limited, and research rarely accounts for how multiple accounts of stigma intersect and contribute to the experiences of marginalized populations. Our research aimed to explore the healthcare experiences of Aboriginal peoples who use illicit drugs and or illicit alcohol (APWUID/A) living in Vancouver's inner city...
January 26, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28213631/destroying-god-s-temple-physical-inactivity-poor-diet-obesity-and-other-sin-behaviors
#18
Mark D Faries, Megan McClendon, Eric J Jones
On average, our participants (N = 112), who self-proclaimed to be Christians, believed that physically inactive lifestyles, unhealthy eating, overeating, and being obese destroy the body, God's temple. However, these beliefs were less definitive, than those of other common "sin" behaviors, such as drug use, smoking, and excessive drinking of alcohol. In addition, destroying the body with physical inactivity or poor diet was not necessarily viewed as sinful. Subsequently, these beliefs did not relate to self-reported physical activity, dietary behavior, or body mass index...
February 17, 2017: Journal of Religion and Health
https://www.readbyqxmd.com/read/28213275/a-single-microfluidic-chip-with-dual-surface-properties-for-protein-drug-delivery
#19
Mehrdad Bokharaei, Katayoun Saatchi, Urs O Häfeli
Principles of double emulsion generation were incorporated in a glass microfluidic chip fabricated with two different surface properties in order to produce protein loaded polymer microspheres. The microspheres were produced by integrating two microfluidic flow focusing systems and a multi-step droplet splitting and mixing system into one chip. The chip consists a hydrophobic and a hydrophilic section with two different heights, 12μm and 45μm, respectively. As a result, the protein is homogenously distributed throughout the polymer microsphere matrix, not just in its center (which has been studied before)...
February 14, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28212981/development-of-solid-sedds-vi-effect-of-precoating-of-neusilin%C3%A2-us2-with-pvp-on-drug-release-from-adsorbed-self-emulsifying-lipid-based-formulations
#20
Suhas G Gumaste, Beatryz O S Freire, Abu T M Serajuddin
Adsorption of lipid-based formulations, which are usually liquid, onto silicas has been extensively investigated in the past decade to convert them into solid dosage forms. There are conflicting reports on the ability of commercially available porous silicas, like Neusilin® US2, to release lipid formulations completely, especially after long-term storage. In this study, the release of a model drug, probucol, from different formulations of medium chain lipids and a surfactant, Kolliphor EL (Cremophor EL) or polysorbate 80, were studied after adsorbing them onto Neusilin® US2...
February 14, 2017: European Journal of Pharmaceutical Sciences
keyword
keyword
105713
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"