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https://www.readbyqxmd.com/read/29784595/comparative-proteome-analysis-of-the-capsule-from-patients-with-frozen-shoulder
#1
Yoshihiro Hagiwara, Masaru Mori, Kenji Kanazawa, Akira Ando, Yutaka Yabe, Masashi Koide, Takuya Sekiguchi, Nobuyuki Itaya, Masahiro Tsuchiya, Eiji Itoi
BACKGROUND: The etiology of frozen shoulder (FS) is unclear. Accordingly, this study used a label-free quantitative shotgun proteomic approach to elucidate the pathogenesis of FS based on protein expression levels. METHODS: Tissue samples from the rotator interval (RI), middle glenohumeral ligament (MGHL), and anterior-inferior glenohumeral ligament (IGHL) were collected from 12 FSs with severe stiffness and 7 shoulders with a rotator cuff tear (RCT) as controls...
May 18, 2018: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/29783070/cdh17-alters-mmp-2-expression-via-canonical-nf-%C3%AE%C2%BAb-signalling-in-human-gastric-cancer
#2
Xiao-Jie Jiang, Jing Lin, Qing-He Cai, Jian-Feng Zhao, Hui-Jiao Zhang
Gastric cancer (GC), one of the most common cancers of the digestive system, results in high morbidity and mortality, but the molecular mechanisms underlying GC remain largely unknown. Cadherin-17 (CDH17) is a nonclassical member of the cadherin (CDH) superfamily of calcium-dependent proteins. Despite recent advances in the understanding of CDH17 biology, the mechanism of CDH17 in GC proliferation, migration, and invasion has not been extensively studied. In the present study, we observed that CDH17 expression was increased in GC tissues compared with para-carcinoma tissues and was correlated with lymph node metastasis and the AJCC stage...
May 18, 2018: Gene
https://www.readbyqxmd.com/read/29783023/extended-spectrum-beta-lactamase-producing-enterobacteriaceae-infections-in-haematopoietic-stem-cell-transplant-recipients-epidemiology-and-molecular-characterization
#3
Molka Kharrat, Yosra Chebbi, Farah Ben Tanfous, Amel Lakhal, Saloua Ladeb, Tarek Ben Othmen, Wafa Achour
BACKGROUND: Extended spectrum β-lactamase producing Enterobacteriaceae (ESBL-E) are feared because they generate therapeutic difficulties and have high potential for dissemination. The purpose of our study was to investigate the epidemiology of these infections in hematopoietic stem cell transplant (HSCT) recipients and to determine the genes encoding ESBL. MATERIAL/METHODS: Our retrospective study concerned adult patients hospitalized at the National Bone Marrow Transplant Center and infected with ESBL-E post HSCT between january 2006 and december 2016...
May 18, 2018: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/29782830/toxoplasma-gondii-infections-in-chickens-performance-of-various-antibody-detection-techniques-in-serum-and-meat-juice-relative-to-bioassay-and-dna-detection-methods
#4
G Schares, M Koethe, B Bangoura, A-C Geuthner, F Randau, M Ludewig, P Maksimov, M Sens, A Bärwald, F J Conraths, I Villena, D Aubert, M Opsteegh, J Van der Giessen
Chickens, especially if free-range, are frequently exposed to Toxoplasma gondii, and may represent an important reservoir for T. gondii. Poultry products may pose a risk to humans, when consumed undercooked. In addition, chickens are regarded as sensitive indicators for environmental contamination with T. gondii oocysts and have been used as sentinels. The aim of the present study was to determine the suitability of commonly used antibody detection methods, i.e. the modified agglutination test (MAT), IFAT and ELISA to detect T...
May 18, 2018: International Journal for Parasitology
https://www.readbyqxmd.com/read/29782007/intraportal-transplantation-of-pancreatic-islets-in-mouse-model
#5
Rahul Khatri, Birte Hussmann, Divya Rawat, Ali Osman Gürol, Thomas Linn
Pancreatic islet transplantation to reduce hyperglycemia is highly successful in rodents with chemically-induced diabetes. The most common transplantation site in experimental islet transplantation is the kidney capsule. However, as less is known about the interaction of pancreatic islets with blood constituents, it also makes sense to utilize the portal vein approach in experimental islet transplantation. This protocol demonstrates an intraportal islet transplantation technique in NMRI nude mice. Streptozotocin (180 mg/kg) is injected intraperitoneally to induce hyperglycemia in recipient mice...
May 5, 2018: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29778485/meta-analysis-of-2-hydroxy-4-methylthio-butanoic-acid-supplementation-on-ruminal-fermentation-milk-production-and-nutrient-digestibility
#6
X Feng, R R White, H A Tucker, M D Hanigan
Methionine is considered one of the most important essential AA for milk protein synthesis in dairy cows. Supplementation of unprotected, free Met is nearly 100% degraded by ruminal microorganisms, which complicates supplementation. 2-Hydroxy-4-methylthio-butanoic acid (HMTBa) can be converted to Met in the body and is used as a Met source in dairy production. However, results of published studies assessing the effects of supplementing Met sources, including HMTBa, on performance variables are inconsistent...
May 16, 2018: Journal of Dairy Science
https://www.readbyqxmd.com/read/29778479/an-in-vivo-stable-isotope-based-approach-for-assessment-of-absorbed-amino-acids-from-individual-feed-ingredients-within-complete-diets
#7
K A Estes, R R White, P S Yoder, T Pilonero, H Schramm, H Lapierre, M D Hanigan
Accurate assessment of the nutritional content of feed ingredients is required for precise diet formulation. Characterizing ingredients in terms of absorption and digestibility of individual AA is challenging, and this information often relies on indirect methods. The purpose of this research was to evaluate an in vivo stable isotope-based method of determining plasma entry rates of individual AA from feather meal (FM), blood meal (BM), and a rumen-protected AA (RPMet). Abomasal infusions of unprotected Ile, Leu, Met, and sodium caseinate were used as control treatments to assess technique reliability and accuracy...
May 16, 2018: Journal of Dairy Science
https://www.readbyqxmd.com/read/29778475/performance-nutritional-behavior-and-metabolic-responses-of-calves-supplemented-with-forage-depend-on-starch-fermentability
#8
S Mojahedi, M Khorvash, G R Ghorbani, E Ghasemi, M Mirzaei, F Hashemzadeh-Cigari
This study evaluated the interactive effects of forage provision on performance, nutritional behavior, apparent digestibility, rumen fermentation, and blood metabolites of dairy calves when corn grains with different fermentability were used. Sixty 3-d-old Holstein calves were randomly assigned to 1 of 4 treatments in a 2 × 2 factorial arrangement. Dietary treatments were (1) steam-flaked (SF) corn without alfalfa hay (AH) supplementation (SF-NO), (2) SF corn with AH supplementation (SF-AH), (3) cracked (CR) corn without AH supplementation (CR-NO), and (4) CR corn with AH supplementation (CR-AH)...
May 16, 2018: Journal of Dairy Science
https://www.readbyqxmd.com/read/29777169/difructose-dianhydride-improves-intestinal-calcium-absorption-wound-healing-and-barrier-function
#9
Sang In Lee, In Ho Kim
The gastrointestinal tract (GIT) is critical for nutrient absorption and is an important barrier against harmful pathogens and antigens. Difructose anhydrides (DFA)-IVs are nondigestible disaccharides that enhance calcium and iron absorption by affecting the intestinal epithelial tissue. However, their effects on intestinal functions are not fully understood. In this study, we performed a feeding trial and found that dietary DFA-IVs improved growth performance, relative breast muscle and liver weight, and digestibility and blood calcium and iron concentrations in broilers...
May 18, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29775962/preterm-birth-and-oxidative-stress-effects-of-acute-physical-exercise-and-hypoxia-physiological-responses
#10
Agnès Martin, Camille Faes, Tadej Debevec, Chantal Rytz, Grégoire Millet, Vincent Pialoux
Preterm birth is a global health issue that can induce lifelong medical sequela. Presently, at least one in ten newborns are born prematurely. At birth, preterm newborns exhibit higher levels of oxidative stress (OS) due to the inability to face the oxygen rich environment in which they are born into. Moreover, their immature respiratory, digestive, immune and antioxidant defense systems, as well as the potential numerous medical interventions following a preterm birth, such as oxygen resuscitation, nutrition, phototherapy and blood transfusion further contribute to high levels of OS...
May 1, 2018: Redox Biology
https://www.readbyqxmd.com/read/29774828/bilberry-pomace-in-rabbit-nutrition-effects-on-growth-performance-apparent-digestibility-caecal-traits-bacterial-community-and-antioxidant-status
#11
S Dabbou, I Ferrocino, A Kovitvadhi, S Bergagna, D Dezzuto, A Schiavone, L Cocolin, F Gai, V Santoro, L Gasco
Agricultural by-products could be used as alternative raw materials in rabbit nutrition as they have been found to be highly nutritious and low cost feeding sources. The aim of this study was to estimate the nutritive value and potential use of bilberry pomace (BP) for growing rabbits. A total of 144 Grimaud rabbits (35 days old) were allotted to four groups and fed with a diet containing increasing level of BP: BP0 (basal diet), BP5, BP10 and BP15 containing 0, 50, 100 and 150 g/kg respectively. Growth trial lasted 48 days; apparent digestibility was evaluated, starting at 46 days of age, over 4 consecutive days...
May 18, 2018: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/29774337/fermentation-alters-the-bioaccessible-phenolic-compounds-and-increases-the-alpha-glucosidase-inhibitory-effects-of-aronia-juice-in-a-dairy-matrix-following-in-vitro-digestion
#12
Xue Du, Angela D Myracle
The prevalence of diabetes reached 415 million worldwide in 2015. Polyphenol-rich food intake can benefit the glycemic control for individuals with diabetes. Fermentation may increase the bioavailability of polyphenols, which is generally low. Aronia (Aronia melanocarpa) is a polyphenol-rich berry that is native to North America. Proanthocyanins and anthocyanins are the major phenolic compounds in aronia. In this study, aronia kefir was made by fermenting cow's milk with added aronia juice. The changes in bioaccessible polyphenols of aronia kefir during digestion were assessed using an in vitro model...
May 18, 2018: Food & Function
https://www.readbyqxmd.com/read/29773199/health-risk-assessment-of-arsenic-in-realgar-and-niuhuangjiedu-tablets-based-on-pharmacokinetic-study
#13
Xiao Wu, Shanhu Wu, Yuexin Liu, Rong Guan, Fangmei Liang, Min Song, Taijun Hang
NiuHuangJieDu Tablets (NHJDT), a popular realgar (As4 S4 ) containing patented traditional Chinese medicine (TCM), is widely used in the treatment of acute tonsillitis, pharyngitis, periodontitis and mouth ulcer. However, arsenic is considered as one of the most toxic elements, leading to growing concerns about the quality and safety of realgar-containing TCMs recently. In this study, health risk assessment of arsenic in realgar and NHJDT was conducted through oral administration of both substances to rats with single and multiple doses, respectively...
July 2018: Journal of Trace Elements in Medicine and Biology
https://www.readbyqxmd.com/read/29771358/inclusion-of-dietary-%C3%AE-mannanase-improves-performance-and-ileal-digestibility-and-reduces-ileal-digesta-viscosity-of-broilers-fed-corn-soybean-meal-based-diet
#14
B Balasubramanian, S L Ingale, J Hong Park, P C Rathi, S Shanmugam, I H Kim
This study was aimed to evaluate the influence of dietary β-mannanase inclusion on growth performance, apparent ileal digestibility, digesta viscosity, blood metabolites and excreta noxious gas emissions in broilers fed corn-soybean meal based diet. A total of 600 conventional healthy 1-d-old ROSS 308 broilers with body weight 45 ± 0.50 g (mean ± SD) were randomly assigned to 4 dietary treatments with 10 replicates cages, with 15 broilers in each and fed basal diet supplemented to corn-SBM based diets with 0, 2400, 4800, and 7200 MNU β-mannanase/kg for 35 d feeding trial period...
May 16, 2018: Poultry Science
https://www.readbyqxmd.com/read/29770558/pharmacokinetic-and-antimicrobial-activity-of-a-new-carvacrol-based-product-against-a-human-pathogen-campylobacter-jejuni
#15
Marion Allaoua, Pierre Etienne, Virginie Noirot, Jean-Luc Carayon, Nathan Téné, Elsa Bonnafé, Michel Treilhou
AIM: In vitro and in vivo studies were conducted to test a new carvacrol-based product designed to delay the carvacrol release so that it could reach the caeca of broiler chickens in order to control Campylobacter jejuni. METHODS AND RESULTS: Antimicrobial activity of carvacrol, a constituent of oregano and thyme essential oil, has been demonstrated against C. jejuni in vitro, and this compound was found beneficial for broiler growth. Here, we tested a new liquid formulation that did not change the antibacterial efficacy of carvacrol against C...
May 16, 2018: Journal of Applied Microbiology
https://www.readbyqxmd.com/read/29770328/second-blood-meal-by-female-lutzomyia-longipalpis-enhancement-by-oviposition-and-its-effects-on-digestion-longevity-and-leishmania-infection
#16
C S Moraes, K Aguiar-Martins, S G Costa, P A Bates, R J Dillon, F A Genta
Lutzomyia longipalpis is the main vector of visceral leishmaniasis (VL) in America. Physiological and molecular mechanisms of Leishmania infection in sand flies have been studied during the first gonotrophic cycle. There are few studies about these interactions during the second gonotrophic cycle mainly because of the difficulties maintaining sand flies through sequential feeds. Here we standardized conditions to perform the second blood feed efficiently, and our results show that oviposition is an essential factor for the success of multiple feeds...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29767749/association-of-brca2-k3326-with-small-cell-lung-cancer-and-squamous-cell-cancer-of-the-skin
#17
Thorunn Rafnar, Gudbjorg R Sigurjonsdottir, Simon N Stacey, Gisli Halldorsson, Patrick Sulem, Luba M Pardo, Hannes Helgason, Stefan T Sigurdsson, Thorkell Gudjonsson, Laufey Tryggvadottir, Gudridur H Olafsdottir, Jon G Jonasson, Kristin Alexiusdottir, Asgeir Sigurdsson, Julius Gudmundsson, Jona Saemundsdottir, Jon K Sigurdsson, Hrefna Johannsdottir, Andre Uitterlinden, Sita H Vermeulen, Tessel E Galesloot, Dawn C Allain, Martin Lacko, Bardur Sigurgeirsson, Kristin Thorisdottir, Oskar T Johannsson, Fridbjorn Sigurdsson, Gunnar B Ragnarsson, Helgi Isaksson, Hronn Hardardottir, Tomas Gudbjartsson, Daniel F Gudbjartsson, Gisli Masson, Lambertus A M L Kiemeney, Amanda Ewart Toland, Tamar Nijsten, Wilbert H M Peters, Jon H Olafsson, Steinn Jonsson, Unnur Thorsteinsdottir, Gudmar Thorleifsson, Kari Stefansson
Background: Most pathogenic mutations in the BRCA2 gene carry a high risk of hereditary breast and ovarian cancer (HBOC). However, a stop-gain mutation, K3326* (rs11571833), confers risk of lung cancer and cancers of the upper-aero-digestive tract but only a modest risk of breast or ovarian cancer. The Icelandic population provides an opportunity for comprehensive characterization of the cancer risk profiles of K3326* and HBOC mutations because a single mutation, BRCA2 999del5, is responsible for almost all BRCA2-related HBOC in the population...
May 14, 2018: Journal of the National Cancer Institute
https://www.readbyqxmd.com/read/29767163/response-of-primiparous-and-multiparous-buffaloes-to-yeast-culture-supplementation-during-early-and-mid-lactation
#18
Hanne H Hansen, Nasr E El-Bordeny, Hossam M Ebeid
Strains of live Saccharomyces cerevisiae yeast have exhibited probiotic effects in ruminants. This study investigated the effects of the dietary yeast supplement, S . cerevisiae (Yea-Sacc1026 ), on primiparous (PP) and multiparous (MP) Egyptian buffaloes in early to mid-lactation. Lactating buffaloes were fed either a basal total mixed ration (TMR, control; 4 PP and 8 MP) or the basal TMR plus 10 g Yea-Sacc1026 per buffalo cow per day (yeast; 4 PP and 8 MP). The feeds were given from 15 days prepartum to 180 days postpartum...
December 2017: Animal nutrition
https://www.readbyqxmd.com/read/29767117/growth-performance-and-hematology-of-djallonk%C3%A3-rams-fed-haulms-of-four-varieties-of-groundnut-arachis-hypogaea-l
#19
Terry Ansah, Zanabongo I Yaccub, Nurudeen A Rahman
The study was conducted to assess the chemical composition of the haulms of 4 dual-purpose groundnut ( Arachis hypogaea L.) varieties and their effects on the growth and hematology of Djallonké rams. The groundnut varieties were ICGV 97049 (Obolo), ICGX SM 87057 (Yenyawoso), RMP 12 (Azivivi) and Manipinta. Rams (live weight 15.0 ± 3.0 kg) were randomly assigned to 4 sole groundnut haulm meal (GHM) treatments, with 4 rams each in an individual pen per treatment (total n  = 16 rams). Samples of the groundnut haulms were milled and analyzed for crude protein (CP), neutral detergent fiber (NDF) and acid detergent fiber (ADF)...
December 2017: Animal nutrition
https://www.readbyqxmd.com/read/29767114/effects-of-physical-form-of-diet-on-nutrient-digestibility-rumen-fermentation-rumination-growth-performance-and-protozoa-population-of-finishing-lambs
#20
Elham Karimizadeh, Morteza Chaji, Tahereh Mohammadabadi
This study was conducted to compare effects of 3 physical forms of feed including mash (diet 1), pellet (diet 2) and complete feed block (CFB; diet 3) on digestion, fermentation and performance of lambs. Twenty-one lambs with an initial average body weight of 26 ± 2.5 kg and 6 ± 1.5 months of age were assigned through a completely randomized design to 3 treatments and 7 replicates. The experimental treatments had the same formulation. The results of present experiment showed that CFB significantly increased feed intake and nutrient digestibility ( P  < 0...
June 2017: Animal nutrition
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