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https://www.readbyqxmd.com/read/28632946/emerging-biomarkers-of-illness-severity-urinary-metabolites-associated-with-sepsis-and-necrotizing-methicillin-resistant-staphylococcus-aureus-pneumonia
#1
Lilliam Ambroggio, Todd A Florin, Samir S Shah, Richard Ruddy, Larisa Yeomans, Julie Trexel, Kathleen A Stringer
STUDY OBJECTIVE: To illustrate the potential of metabolomics to identify novel biomarkers of illness severity in a child with fatal necrotizing pneumonia caused by methicillin-resistant Staphylococcus aureus (MRSA). DESIGN: Case report with two control groups and a metabolomics analysis. PATIENTS: An infant with fatal MRSA pneumonia, four children with influenza pneumonia (pneumonia control group), and seven healthy children with no known infections (healthy control group)...
June 20, 2017: Pharmacotherapy
https://www.readbyqxmd.com/read/28632019/underappreciated-challenges-to-pediatric-powered-mobility-ways-to-address-them-as-illustrated-by-a-case-report
#2
Miriam L Weinstein, Michele Lloyd, Kirstie A Finch, Abbigayle D Laszacs
Rehabilitation Engineering and Assistive Technology Society of North America (RESNA) has published a position paper strongly advocating powered mobility (PM) for children with severe physical limitations (Rosen et al., 2009). Many studies have established that there are gains in social skills and functional mobility. While PM can aid independence, there has been more emphasis on the improvements in socialization rather than the positive changes PM can make in a child's daily living. For example, Bottos and colleagues stated the quality of life did not change for the children in their study (2001)...
February 14, 2017: Assistive Technology: the Official Journal of RESNA
https://www.readbyqxmd.com/read/28632018/exploring-the-learnability-and-usability-of-a-near-field-communication-based-application-for-semantic-enrichment-in-children-with-language-disorders
#3
Maria Luisa Lorusso, Emilia Biffi, Massimo Molteni, Gianluigi Reni
Recently, a few software applications (apps) have been developed to enhance vocabulary and conceptual networks to address the needs of children with language impairments (LI), but there is no evidence about their impact and their usability in therapy contexts. Here, we try to fill this gap presenting a system aimed at improving the semantic competence and the structural knowledge of children with LI. The goal of the study is to evaluate learnability, usability, user satisfaction and quality of the interaction between the system and the children...
February 13, 2017: Assistive Technology: the Official Journal of RESNA
https://www.readbyqxmd.com/read/28627356/aquatic-therapy-for-children-with-duchenne-muscular-dystrophy-a-pilot-feasibility-randomised-controlled-trial-and-mixed-methods-process-evaluation
#4
Daniel Hind, James Parkin, Victoria Whitworth, Saleema Rex, Tracey Young, Lisa Hampson, Jennie Sheehan, Chin Maguire, Hannah Cantrill, Elaine Scott, Heather Epps, Marion Main, Michelle Geary, Heather McMurchie, Lindsey Pallant, Daniel Woods, Jennifer Freeman, Ellen Lee, Michelle Eagle, Tracey Willis, Francesco Muntoni, Peter Baxter
BACKGROUND: Duchenne muscular dystrophy (DMD) is a rare disease that causes the progressive loss of motor abilities such as walking. Standard treatment includes physiotherapy. No trial has evaluated whether or not adding aquatic therapy (AT) to land-based therapy (LBT) exercises helps to keep muscles strong and children independent. OBJECTIVES: To assess the feasibility of recruiting boys with DMD to a randomised trial evaluating AT (primary objective) and to collect data from them; to assess how, and how well, the intervention and trial procedures work...
May 2017: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/28621219/manualization-of-occupational-therapy-using-ayres-sensory-integration%C3%A2-for-autism
#5
Joanne Hunt, Elke van Hooydonk, Patricia Faller, Zoe Mailloux, Roseann Schaaf
This article reports on the development of a Stage 3 manual (following pilot effectiveness study) for implementing occupational therapy using Ayres Sensory Integration® (OT/ASI) for children with autism spectrum disorders to enhance participation in daily occupations. Three stakeholder groups were surveyed to aid in translation of manual from research to practice (i.e., Stage 3 manual) and an expert consensus meeting was held to finalize recommendations. Data indicated that the manuals usability could be improved by including a section on frequently encountered problems and solutions, and by including video case examples...
July 2017: OTJR: Occupation, Participation and Health
https://www.readbyqxmd.com/read/28621001/early-vocabulary-development-in-children-with-bilateral-cochlear-implants
#6
Taina Välimaa, Sari Kunnari, Päivi Laukkanen-Nevala, Eila Lonka
BACKGROUND: Children with unilateral cochlear implants (CIs) may have delayed vocabulary development for an extended period after implantation. Bilateral cochlear implantation is reported to be associated with improved sound localization and enhanced speech perception in noise. This study proposed that bilateral implantation might also promote early vocabulary development. Knowledge regarding vocabulary growth and composition in children with bilateral CIs and factors associated with it may lead to improvements in the content of early speech and language intervention and family counselling...
June 16, 2017: International Journal of Language & Communication Disorders
https://www.readbyqxmd.com/read/28620635/pioneering-strategies-for-relieving-dental-anxiety-in-hearing-impaired-children-a-randomized-controlled-clinical-study
#7
Shalini Chandrasekhar, Ghanashyam Prasad Madu, Naga Radhakrishna Ambati, Pavani Reddy Suravarapu, Kalyani Uppu, Deepthi Bolla
STATEMENT OF THE PROBLEM: Hearing impaired children have a problem in understanding and comprehending with dental treatments. Visual language is the sensible answer of how to improve communication with them. PURPOSE: To evaluate the applicability of dental sign language in Hearing impaired children in relieving anxiety during stressful dental treatment by improving their means of communication. MATERIALS AND METHOD: This randomized clinical trial was carried out in the Department of Pedodontics and Preventive Dentistry which included 40 Hearing Impaired children meeting inclusion criteria...
June 2017: Journal of Dentistry
https://www.readbyqxmd.com/read/28619407/should-they-also-have-babies-community-attitudes-toward-sexual-and-reproductive-rights-of-people-living-with-hiv-aids-in-nigeria
#8
Zubairu Iliyasu, Hadiza S Galadanci, Yusuf A Ibrahim, Musa Babashani, Mohammed S Mijinyawa, Melynda Simmons, Muktar H Aliyu
BACKGROUND: People living with HIV have the right to healthy, satisfying sex lives and to appropriate services to ensure their sexual and reproductive health, including having healthy children. The reproductive rights of people living with HIV/AIDS are, however, often met with skepticism and discrimination, despite recent advances in HIV treatment. OBJECTIVE: To assess the attitudes of community members in Kano, Nigeria, toward the right of persons living with HIV/AIDS to have healthy sexual relationships and bear children...
March 2017: Annals of Global Health
https://www.readbyqxmd.com/read/28619306/management-of-viral-oral-ulcers-in-children-using-chinese-herbal-medicine-a-report-of-two-cases
#9
Yi-Chiao Lee, Ting-Hao Wang, Shih-Yu Chen, Hsiang-Ling Lin, Ming-Yen Tsai
OBJECTIVE: Viral oral ulcers are common presentations in pediatric clinics. Although self-limiting, painful ulcerative lesions and inflamed mucosa can decrease oral intake and lead to dehydration. Despite the widespread use of Chinese herbal medicine (CHM) for pediatric upper respiratory disease in Taiwan, there is little evidence for its effectiveness as an antipyretic or in aiding ulcer healing for children with viral oral ulcers. We report two cases of children who presented with viral oral ulcers to illustrate the potential efficacy of CHM treatment in recovery from herpangina (HA) and herpetic gingivostomatitis (HGS)...
June 2017: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/28617820/defining-health-related-quality-of-life-for-young-wheelchair-users-a-qualitative-health-economics-study
#10
Nathan Bray, Jane Noyes, Nigel Harris, Rhiannon Tudor Edwards
BACKGROUND: Wheelchairs for children with impaired mobility provide health, developmental and psychosocial benefits, however there is limited understanding of how mobility aids affect the health-related quality of life of children with impaired mobility. Preference-based health-related quality of life outcome measures are used to calculate quality-adjusted life years; an important concept in health economics. The aim of this research was to understand how young wheelchair users and their parents define health-related quality of life in relation to mobility impairment and wheelchair use...
2017: PloS One
https://www.readbyqxmd.com/read/28617810/population-level-impact-of-an-accelerated-hiv-response-plan-to-reach-the-unaids-90-90-90-target-in-c%C3%A3-te-d-ivoire-insights-from-mathematical-modeling
#11
Mathieu Maheu-Giroux, Juan F Vesga, Souleymane Diabaté, Michel Alary, Stefan Baral, Daouda Diouf, Kouamé Abo, Marie-Claude Boily
BACKGROUND: National responses will need to be markedly accelerated to achieve the ambitious target of the Joint United Nations Programme on HIV/AIDS (UNAIDS). This target aims for 90% of HIV-positive individuals to be aware of their status, for 90% of those aware to receive antiretroviral therapy (ART), and for 90% of those on treatment to have a suppressed viral load by 2020, with each individual target reaching 95% by 2030. We aimed to estimate the impact of various treatment-as-prevention scenarios in Côte d'Ivoire, one of the countries with the highest HIV incidence in West Africa, with unmet HIV prevention and treatment needs, and where key populations are important to the broader HIV epidemic...
June 2017: PLoS Medicine
https://www.readbyqxmd.com/read/28617614/effects-of-background-color-and-symbol-arrangement-cues-on-construction-of-multi-symbol-messages-by-young-children-without-disabilities-implications-for-aided-aac-design
#12
Jennifer J Thistle, Krista Wilkinson
Children whose speech does not meet their communication needs often benefit from augmentative and alternative communication (AAC). The design of an AAC display may influence the child's ability to communicate effectively. The current study examined how symbol background color cues and symbol arrangement affected construction of multi-symbol messages using line-drawing symbols, by young children with typical development. Participants (N = 52) heard a spoken phrase matching a photograph and selected line drawings within a 4 × 4 array...
June 15, 2017: Augmentative and Alternative Communication: AAC
https://www.readbyqxmd.com/read/28615652/development-of-a-computer-aided-design-and-finite-element-analysis-combined-method-for-customized-nuss-bar-in-pectus-excavatum-surgery
#13
Longhan Xie, Siqi Cai, Liang Xie, Gang Chen, Haiyu Zhou
Pectus excavatum (PEX) is the most common chest deformity in children, which is usually corrected by using the minimally invasive Nuss method. The orthopedic effect of the Nuss operation is mainly evaluated by both the Haller index and the appearance of the chest wall configuration, which is dependent on the operator's clinical experience to a great extent. To improve the orthopedic effect, we proposed a novel method to individually design and optimize the shape of the Nuss bar and to advise its location as well as the incisions...
June 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28615391/practical-approach-to-evaluating-testicular-status-in-infants-and-children
#14
REVIEW
Elke E Mau, Michael P Leonard
OBJECTIVE: To review the differences between normal, retractile, ectopic, ascended, and undescended testes and to describe the optimal way to perform a testicular examination to distinguish one from the other, as well as to demonstrate that ultrasound imaging is not necessary and to clarify when to consider specialist referral. SOURCES OF INFORMATION: This paper is based on selected findings from a MEDLINE search on undescended testes and orchiopexy referrals, and on our experience at the Urology Clinic at the Children's Hospital of Eastern Ontario in Ottawa, including review of referrals to our clinic for undescended testes and the resultant findings of normal variants versus surgical cases...
June 2017: Canadian Family Physician Médecin de Famille Canadien
https://www.readbyqxmd.com/read/28613961/school-based-multi-tiered-systems-of-support-mtss-an-introduction-to-mtss-for-neuropsychologists
#15
Danielle Wexler
When completing pediatric neuropsychological evaluations, it is important for clinicians to incorporate data from children's school environments. Today, the educational data available to neuropsychologists have resulted from the utilization of multi-tiered systems of support (MTSS) within schools; however, practitioners may lack knowledge and/or training in this school-based approach to assessment and intervention. Better understanding of MTSS may aid pediatric neuropsychologists in their interpretation and use of educational data commonly provided by schools...
June 14, 2017: Applied Neuropsychology. Child
https://www.readbyqxmd.com/read/28613187/detection-of-nocturnal-scratching-movements-in-patients-with-atopic-dermatitis-using-accelerometers-and-recurrent-neural-networks
#16
Arnaud Moreau, Peter Anderer, Marco Ross, Andreas Cerny, Timothy Almazan, Barry Peterson
Atopic dermatitis is a chronic inflammatory skin condition affecting both children and adults and is associated with pruritus. A method for objectively quantifying nocturnal scratching events could aid in the development of therapies for atopic dermatitis and other pruritic disorders. High-resolution wrist actigraphy (3-D accelerometer sensors sampled at 20 Hz) is a non-invasive method to record movement. This work presents an algorithm to detect nocturnal scratching events based on actigraphy data. The twofold process consists of segmenting the data into "no motion", "single handed motion" and "both handed motion" followed by discriminating motion segments into scratching and other motion using a bi-directional recurrent neural network classifier...
June 8, 2017: IEEE Journal of Biomedical and Health Informatics
https://www.readbyqxmd.com/read/28612384/exploring-partner-intimacy-among-couples-raising-children-on-the-autism-spectrum-a%C3%A2-grounded-theory-investigation
#17
Jake Johnson, Fred P Piercy
In this study, we explored how couples raising children with autism spectrum disorder negotiate intimacy, including what contextual and temporal factors influence these processes. We conducted conjoint interviews with 12 couples, employing grounded theory methodology to collect and analyze the data. Our results indicated that fostering intimacy in these couples' relationships involves partners working together to make key cognitive and relational shifts. Couples are aided or hindered in making these shifts by the degree to which they experience various contextual and environmental factors as resources or roadblocks...
June 13, 2017: Journal of Marital and Family Therapy
https://www.readbyqxmd.com/read/28612343/mild-moderate-congenital-hearing-loss-secular-trends-in-outcomes-across-four-systems-of-detection
#18
P Carew, F K Mensah, G Rance, T Flynn, Z Poulakis, M Wake
BACKGROUND: Universal newborn hearing screening (UNHS) targets moderate or greater hearing loss. However, UNHS also frequently detects children with mild loss that results in many receiving early treatment. The benefits of this approach are not yet established. We aimed to (i) compare language and psychosocial outcomes between four hearing loss detection systems for children aged 5-8 years with congenital mild-moderate hearing loss; (ii) determine whether age of detection predicts outcomes; and (iii) compare outcomes between children identified via well-established UNHS and the general population...
June 14, 2017: Child: Care, Health and Development
https://www.readbyqxmd.com/read/28610606/biologic-therapies-for-refractory-juvenile-dermatomyositis-five-years-of-experience-of-the-childhood-arthritis-and-rheumatology-research-alliance-in-north-america
#19
C H Spencer, K Rouster-Stevens, H Gewanter, G Syverson, R Modica, K Schmidt, H Emery, C Wallace, S Grevich, K Nanda, Y D Zhao, S Shenoi, S Tarvin, S Hong, C Lindsley, J E Weiss, M Passo, K Ede, A Brown, K Ardalan, W Bernal, M L Stoll, B Lang, R Carrasco, C Agaiar, L Feller, H Bukulmez, R Vehe, H Kim, H Schmeling, D Gerstbacher, M Hoeltzel, B Eberhard, R Sundel, S Kim, A M Huber, A Patwardhan
BACKGROUND: The prognosis of children with juvenile dermatomyositis (JDM) has improved remarkably since the 1960's with the use of corticosteroid and immunosuppressive therapy. Yet there remain a minority of children who have refractory disease. Since 2003 the sporadic use of biologics (genetically-engineered proteins that usually are derived from human genes) for inflammatory myositis has been reported. In 2011-2016 we investigated our collective experience of biologics in JDM through the Childhood Arthritis and Rheumatology Research Alliance (CARRA)...
June 13, 2017: Pediatric Rheumatology Online Journal
https://www.readbyqxmd.com/read/28607211/consensus-statement-of-the-indian-academy-of-pediatrics-on-newborn-hearing-screening
#20
Abraham Paul, Chhaya Prasad, S S Kamath, Samir Dalwai, M K C Nair, Waheeda Pagarkar
JUSTIFICATION: Hearing impairment is one of the most critical sensory impairments with significant social and psychological consequences. Reported incidence of congenital hearing loss is 30 per 10,000 children. Evidence-based, standardized national guidelines are needed for professionals to screen for hearing impairment during the neonatal period. PROCESS: The meeting on formulation of national consensus guidelines on developmental disorders was organized by Indian Academy of Pediatrics in Mumbai, on 18th and 19th December, 2015...
June 4, 2017: Indian Pediatrics
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