keyword
MENU ▼
Read by QxMD icon Read
search

up date

keyword
https://www.readbyqxmd.com/read/29679771/extracorporeal-photopheresis-improves-survival-in-hematopoietic-cell-transplant-patients-with-bronchiolitis-obliterans-syndrome-without-significantly-impacting-measured-pulmonary-functions
#1
Mehrdad Hefazi, Kimberly J Langer, Nandita Khera, Jill Adamski, Vivek Roy, Jeffrey L Winters, Dennis A Gastineau, Eapen K Jacob, Justin D Kreuter, Manish J Gandhi, William J Hogan, Mark R Litzow, Shahrukh K Hashmi, Hemang Yadav, Vivek N Iyer, J P Scott, Mark E Wylam, Rodrigo Cartin-Ceba, Mrinal M Patnaik
We carried out the first matched retrospective cohort study aimed at studying the safety and efficacy of extracorporeal photopheresis (ECP) for bronchiolitis obliterans syndrome (BOS) following allogeneic hematopoietic cell transplantation (HCT). Medical records of 1325 consecutive adult patients who underwent HCT between 2005 and 2015 were reviewed. Seventy-four patients (median age, 51 years) with a diagnosis of BOS were included in the study. After propensity-score matching for BOS severity, 26 patients who underwent ≥3 months of ECP were matched to 26 non-ECP-treated patients, who were assigned an index date corresponding to the ECP start date for their matched pairs...
April 18, 2018: Biology of Blood and Marrow Transplantation
https://www.readbyqxmd.com/read/29679724/harvest-and-trade-of-caterpillar-mushroom-ophiocordyceps-sinensis-and-the-implications-for-sustainable-use-in-the-tibet-region-of-southwest-china
#2
Jun He
ETHNOPHARMACOLOGICAL RELEVANCE: caterpillar mushroom (Ophiocordyceps sinensis) is a unique medicinal fungi which is only found in alpine grasslands in Himalayan mountain regions and the Tibetan Plateau. Known locally as Yartsa Gunbu, it has been widely used in Tibetan and Chinese Medicine for centuries. It is crucial to understand local commercial harvest and trade practices of caterpillar mushroom to support the sustainable management of this valuable resource. However, data derived from empirically grounded research is currently limited, particularly in China...
April 18, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29679170/light-localization-with-low-contrast-targets-in-a-patient-implanted-with-a-suprachoroidal-transretinal-stimulation-retinal-prosthesis
#3
Takao Endo, Takashi Fujikado, Masakazu Hirota, Hiroyuki Kanda, Takeshi Morimoto, Kohji Nishida
PURPOSE: To evaluate the improvement in targeted reaching movements toward targets of various contrasts in a patient implanted with a suprachoroidal-transretinal stimulation (STS) retinal prosthesis. METHODS: An STS retinal prosthesis was implanted in the right eye of a 42-year-old man with advanced Stargardt disease (visual acuity: right eye, light perception; left eye, hand motion). In localization tests during the 1-year follow-up period, the patient attempted to touch the center of a white square target (visual angle, 10°; contrast, 96, 85, or 74%) displayed at a random position on a monitor...
April 20, 2018: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/29678710/pediatric-type-follicular-lymphoma-in-the-dura-a-case-report-and-literature-review
#4
Junya Yamaguchi, Seiichi Kato, Eri Iwata, Kosuke Aoki, Ryusuke Kabeya, Atsushi Natsume, Toshihiko Wakabayashi
BACKGROUND: Primary central nervous system lymphoma (PCNSL) is a relatively common tumor of the central nervous system. Although PCNSLs generally arise from the parenchyma, lymphomas arising primarily from the dura are termed dural lymphomas (DL). Mucosa-associated lymphoid tissue is the most unique histological feature of DL. Due to its rarity, clinical characteristics and treatments for DL have not been fully elucidated to date. CASE DESCRIPTION: A 31-year-old man with no past medical history presented with numbness in his left upper limb...
April 17, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29678401/geographical-distribution-climate-adaptation-and-vector-competence-of-the-eurasian-hard-tick-haemaphysalis-concinna
#5
Franz Rubel, Katharina Brugger, Melanie Walter, Janna R Vogelgesang, Yuliya M Didyk, Su Fu, Olaf Kahl
The ixodid tick Haemaphysalis concinna Koch, 1844 is a proven vector of tick-borne encephalitis (TBE) virus and Francisella tularensis, the causative agent of tularaemia. In the present study, up-to-date maps depicting the geographical distribution and climate adaptation of H. concinna are presented. A dataset was compiled, resulting in 656 georeferenced locations in Eurasia. The distribution of H. concinna ranges from the Spanish Atlantic coast to Kamchatka, Russia, within the belt of 28-64° N latitude...
April 10, 2018: Ticks and Tick-borne Diseases
https://www.readbyqxmd.com/read/29678285/pharmacogenetics-of-g-protein-coupled-receptors-variants-fsh-receptor-and-infertility-treatment
#6
REVIEW
Daniele Santi, Francesco Potì, Manuela Simoni, Livio Casarini
Infertility treatment may represent a paradigmatic example of precision medicine. Follicle-stimulating hormone (FSH) has been proposed as a valuable therapeutic option both in males and in females, even if a standardized approach is far to be established. To date, several genetic mutations as well as polymorphisms have been demonstrated to significantly affect the pathophysiology of FSH-FSH receptor (FSHR) interaction, although the underlying molecular mechanisms remain unclear. This review aims to highlight possible aspects of FSH therapy that could benefit from a pharmacogenetic approach, providing an up-to-date overview of the variability of the response to FSH treatment in both sexes...
April 2018: Best Practice & Research. Clinical Endocrinology & Metabolism
https://www.readbyqxmd.com/read/29678189/accepting-telemedicine-in-a-circulatory-medicine-ward-in-major-hospitals-in-south-korea-patients-and-health-professionals-perception-of-real-time-electrocardiogram-monitoring
#7
Seo-Joon Lee, Tae-Young Jung, Tae-Ro Lee, Jae-Hoon Han
BACKGROUND: South Korean government is currently in progress of expanding the coverage of telemedicine projects as part of an attempt to vitalize service industry, but is facing fierce opposition from KMA. Practice of telemedicine requires sufficient discussions among related parties. Although the participation of medical specialists is important, agreement from the public is essential. METHODS: Three main tertiary care centers in Seoul were selected for data collection...
April 20, 2018: BMC Health Services Research
https://www.readbyqxmd.com/read/29678155/a-stepped-wedge-implementation-and-evaluation-of-the-healthy-active-peaceful-playgrounds-for-youth-happy-intervention
#8
Dean Dudley, Wayne Cotton, Louisa Peralta, Matthew Winslade
BACKGROUND: Increasing physical activity in children is a health priority. The Healthy Active Peaceful Playgrounds for Youth (HAPPY) study aimed to examine a multi-component playground intervention designed to increase the proportion of physical activity during recess and lunch of primary school students. METHODS: The 2016 Australian focused HAPPY Study was a 12-month, metropolitan primary school based intervention, which was evaluated using a stepped wedge design...
April 20, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29678018/advantages-of-a-web-based-real-time-bed-management-system-for-hospital-admission-monitoring-in-iran
#9
Somayeh Abedian, Ehsan Bitaraf, Marjan Askari
Lack of up-to-date information of hospitals beds, specifically in emergencies, is a significant problem in many large countries; The Ministry of Health and Medical Education of Iran (MOHME) designed and implemented a dynamic system that reports the status of beds in 2012. This system created great opportunities for national bed management, including real-time hospital admission monitoring, especially for emergency departments, ICUs and CCUs. Therefore, an additional online system was planned to be implemented for monitoring hospital admissions, including a national alert system...
2018: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/29677988/gaining-insights-on-nasopharyngeal-carcinoma-treatment-outcome-using-clinical-data-mining-techniques
#10
A Ammar Ghaibeh, Asem Kasem, Xun Jin Ng, Hema Latha Krishna Nair, Jun Hirose, Vinesh Thiruchelvam
The analysis of Electronic Health Records (EHRs) is attracting a lot of research attention in the medical informatics domain. Hospitals and medical institutes started to use data mining techniques to gain new insights from the massive amounts of data that can be made available through EHRs. Researchers in the medical field have often used descriptive statistics and classical statistical methods to prove assumed medical hypotheses. However, discovering new insights from large amounts of data solely based on experts' observations is difficult...
2018: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/29676798/afferent-neural-feedback-overrides-the-modulating-effects-of-arousal-hypercapnia-and-hypoxemia-on-neonatal-cardio-respiratory-control
#11
Kathleen J Lumb, Jennifer M Schneider, Thowfique Ibrahim, Anita Rigaux, Shabih U Hasan
KEY POINTS: Evidence at whole animal, organ-system, and cellular and molecular levels suggests that afferent volume feedback is critical for establishment of adequate ventilation at birth. Due to the irreversible nature of vagal ablation studies to date, it was difficult to quantify the roles of afferent volume input, arousal and changes in blood gas tensions on neonatal respiratory control. During reversible perineural vagal block, profound apneas, and hypoxemia and hypercarbia were observed necessitating termination of perineural blockade...
April 20, 2018: Journal of Physiology
https://www.readbyqxmd.com/read/29676734/flows-ecology-and-people-is-there-room-for-cultural-demands-in-the-assessment-of-environmental-flows
#12
Fernando Magdaleno
The science and practice of environmental flows - aimed at the protection of ecosystem values and functions in regulated rivers - has progressively recognized the relevance of incorporating socio-cultural demands of local communities in the calculation of water requirements of rivers' habitats and services. This review paper synthesizes the concept of cultural flows, and presents the main approaches explored or conducted up to this date to provide such flows in rivers of different regions and typology. This work highlights the necessity of integrating cultural demands in future attempts to protect and restore altered flow patterns, due to the multiple interactions between flow, ecology and people which typically characterize rivers and other aquatic systems...
April 2018: Water Science and Technology: a Journal of the International Association on Water Pollution Research
https://www.readbyqxmd.com/read/29676625/exposomics-based-analysis-of-environmental-factors-associated-with-forced-expiratory-volume-in-1-second-at-6-months-post-lung-transplantation
#13
Michelle L North, Musawir Ahmed, Sepehr Salehi, Kavindi Jayasinghe, Manisha Tilak, Joyce Wu, Cheol-Heon Jeong, Greg J Evans, Chung-Wai Chow
RATIONALE: Chronic lung allograft dysfunction is the biggest impediment to long-term survival after lung transplantation. Studies have shown an increased risk for chronic lung allograft dysfunction in patients exposed to traffic-related air pollution, using residential distance to roadways and outdoor pollution. OBJECTIVES: Personal monitoring and the indoor environment post-lung transplantation have not been investigated. The exposome is a novel conceptual framework that allows for concurrent examination of multiple intrinsic and extrinsic factors, including environmental exposures, as well as changes in exposures over time, to elucidate the complex environmental factors that affect health outcomes...
April 2018: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/29676221/prognostic-biomarkers-for-cholangiocarcinoma-and-their-clinical-implications
#14
Charupong Saengboonmee, Kanlayanee Sawanyawisuth, Yoavalux Chamgramol, Sopit Wongkham
Cholangiocarcinoma (CCA) is a poorly prognostic cancer with limited treatment options. Most patients have unresectable tumors when they are diagnosed and the chemotherapies provided are of limited benefit. Prognostic markers are therefore necessary to predict the disease outcome, risk of relapse, or to suggest the best treatment option. Areas covered: This article provides an up-to-date review of biomarkers with promising characteristics to be prognostic markers for CCA reported in the past 5 years. The biomarkers are sub-classified into tissue and serum markers...
April 20, 2018: Expert Review of Anticancer Therapy
https://www.readbyqxmd.com/read/29676043/mitral-valve-interventions-in-heart-failure
#15
REVIEW
Daniel Lavall, Andreas Hagendorff, Stephan H Schirmer, Michael Böhm, Michael A Borger, Ulrich Laufs
Secondary mitral regurgitation (MR) results from left ventricular dilatation and dysfunction. Quantification of secondary MR is challenging because of the underlying myocardial disease. Clinical and echocardiographic evaluation requires a multi-parametric approach. Severe secondary MR occurs in up to one-fourth of patients with heart failure with reduced ejection fraction, which is associated with a mortality rate of 40% to 50% in 3 years. Percutaneous edge-to-edge mitral valve repair (MitraClip) has emerged as an alternative to surgical valve repair to improve symptoms, functional capacity, heart failure hospitalizations, and cardiac haemodynamics...
April 19, 2018: ESC Heart Failure
https://www.readbyqxmd.com/read/29675805/enhanced-extracellular-pullulanase-production-in-bacillus-subtilis-using-protease-deficient-strains-and-optimal-feeding
#16
Kang Zhang, Lingqia Su, Jing Wu
To study the effect of proteases on pullulanase production, six protease-encoding genes (nprB, bpr, mpr, epr, vpr, and wprA) in the genome of Bacillus subtilis strain WS5, which already lacks the protease-encoding genes nprE and aprE, were sequentially disrupted using a CRISPR/Cas9 system. This created strains WS6-WS11, respectively. The strains WS3 (none) and WS4 (ΔnprE) were constructed earlier. After addition of expression plasmid pHYPULd4 into the strains WS3-WS11, the pullulanase production levels of the resulting strains (WS3PUL-WS11PUL, respectively) were investigated in shake-flask cultivations and recombinant strain WS5PUL produced the highest pullulanase activity (148...
April 20, 2018: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/29675797/treatment-intensification-in-type-2-diabetes-a-real-world-study-of-2-oad-regimens-glp-1-ras-or-basal-insulin
#17
Lawrence Blonde, Denis Raccah, Elisheva Lew, Juliana Meyers, Elena Nikonova, Mayank Ajmera, Keith L Davis, Monica Bertolini, Bruno Guerci
INTRODUCTION: Treatment guidelines recommend a stepwise approach to glycemia management in patients with type 2 diabetes (T2D), but this may result in uncontrolled glycated hemoglobin A1c (HbA1c) between steps. This retrospective analysis compared clinical and economic outcomes among patients with uncontrolled T2D initiating two oral antidiabetes drugs (OADs), glucagon-like peptide-1 receptor agonists (GLP-1 RAs), or basal insulin in a real-world setting. METHODS: Adults with T2D on OAD monotherapy were identified in the MarketScan claims database (2007-2014)...
April 19, 2018: Diabetes Therapy: Research, Treatment and Education of Diabetes and related Disorders
https://www.readbyqxmd.com/read/29675525/the-effect-of-aluminum-and-platinum-additives-on-hydrogen-adsorption-on-mesoporous-silicates
#18
Gérôme Melaet, Vitalie Stavila, Lennie Klebanoff, Gabor A Somorjai
Recent theoretical predictions indicate that functional groups and additives could have a favorable impact on the hydrogen adsorption characteristics of sorbents; however, no definite evidence has been obtained to date and little is known about the impact of such modifications on the thermodynamics of hydrogen uptake and overall capacity. In this work, we investigate the effect of two types of additives on the cryoadsorption of hydrogen to mesoporous silica. First, Lewis and Brønsted acid sites were evaluated by grafting aluminum to the surface of mesoporous silica (MCF-17) and characterizing the resulting silicate materials' surface area and the concentration of Brønsted and Lewis acid sites created...
April 20, 2018: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29675480/pituitary-dysfunction-from-an-unruptured-ophthalmic-internal-carotid-artery-aneurysm-with-improved-2-year-follow-up-results-a-case-report
#19
Meng Qi, Ming Ye, Meng Li, Peng Zhang
Internal carotid artery (ICA) supraclinoid segment aneurysms extending into the sellar region and leading to pituitary dysfunction are a rare occurrence. To date, long-term follow up of pituitary function 2 years post-treatment has never been reported. Herein, we present a case of pituitary dysfunction due to an unruptured ophthalmic segment internal carotid artery aneurysm and report improved 2-year follow-up results. A 76-year-old male presented with disturbed consciousness due to hyponatremia, which was caused by hypoadrenocorticism resulting from pituitary dysfunction complicated by hypogonadism and hypothyroidism...
2018: Open Medicine (Warsaw, Poland)
https://www.readbyqxmd.com/read/29674880/-paravietnura-gen-n-a-new-intriguing-genus-of-neanurini-from-the-caucasus-collembola-neanuridae-neanurinae
#20
Adrian Smolis, Nataliya Kuznetsova
Paravietnura gen. n. is described and established for two new species of Neanurini from the Caucasus. The new genus is characterized by an unusual combination of features: the fusion of all lateral tubercles on the head into a single mass, the strong reduction of chaetae on the head, the fusion of cephalic tubercles Af and Oc into a transverse band, the absence of labial chaetae f, the presence of microchaetae on furca rudimentary, and the penultimate abdominal tergum with two tubercles separated along the midline...
2018: ZooKeys
keyword
keyword
105702
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"