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space travel

Anna Jafarpour, Hugo Spiers
When humans draw maps, or make judgments about travel-time, their responses are rarely accurate and are often systematically distorted. Distortion effects on estimating time to arrival and the scale of sketch-maps reveal the nature of mental representation of time and space. Inspired by data from rodent entorhinal grid cells, we predicted that familiarity to an environment would distort representations of the space by expanding the size of it. We also hypothesized that travel-time estimation would be distorted in the same direction as space-size, if time and space rely on the same cognitive map...
October 22, 2016: Hippocampus
Subhadip Goswami, Lin Ma, Alex B F Martinson, Michael R Wasielewski, Omar K Farha, Joseph T Hupp
Owing to their ability to act as light-harvesting scaffolds, porphyrin-containing metal-organic frameworks (MOFs) are in the forefront of research on the application of highly ordered molecular materials to problems in solar-energy conversion. In this work, solvent assisted linker exchange (SALE) is performed on a pillared paddlewheel porphyrin containing MOF thin film to collapse a 3D-framework to a 2D-framework. The change in dimensionality of the framework is confirmed by a decrease in the film thickness, the magnitude of which is in agreement with crystallographic parameters for related bulk materials...
October 21, 2016: ACS Applied Materials & Interfaces
Juan Pablo Amaya, Juan I Areta, Veronica S Valentinuzzi, Emmanuel Zufiaurre
The underground environment poses particular communication challenges for subterranean rodents. Some loud and low-pitched acoustic signals that can travel long distances are appropriate for long-range underground communication and have been suggested to be territorial signals. Long-range vocalizations (LRVs) are important in long-distance communication in Ctenomys tuco-tucos. We characterized the LRV of the Anillaco Tuco-Tuco (Ctenomys sp.) using recordings from free-living individuals and described the behavioral context in which this vocalization was produced during laboratory staged encounters between individuals of both sexes...
2016: PeerJ
Adrian Dobra, Till Bärnighausen, Alain Vandormael, Frank Tanser
OBJECTIVE: To quantify the space-time dimensions of human mobility in relationship to the risk of HIV acquisition. METHODS: We used data from the population cohort located in a high HIV-prevalence, rural population in KwaZulu-Natal, South Africa (2000 - 2014). We geolocated 8,006 migration events (representing 1,028,782 km travelled) for 17,743 individuals (≥15 years of age) who were HIV-negative at baseline and followed-up these individuals for HIV acquisition (70,395 person-years)...
October 14, 2016: AIDS
Lin Zhao, Dongxue Guan, Jianhua Cheng, Xiaomin Xu, Zaihui Fei
A ship experiences the random motion of sea waves during its travels. Hence, the coarse alignment of the marine strapdown Inertial Navigation System (INS) suffers from rocking disturbances such as pitch and roll. In this paper, a novel approach of marine coarse alignment was proposed for avoiding the resulting loss of accuracy from rocking disturbances. Unlike several current techniques, our alignment scheme is intuitional and concise. Moreover, the coarse alignment can be implemented without any external information...
October 15, 2016: Sensors
Kjetil Lysne Voje
The dominating view of evolution based on the fossil record is that established species remain more or less unaltered during their existence. Substantial evolution is on the other hand routinely reported for contemporary populations, and most quantitative traits show high potential for evolution. These contrasting observations on long and short time scales are often referred to as the paradox of stasis, which rests on the fundamental assumption that periods of morphological stasis in the fossil record represent minimal evolutionary change...
October 17, 2016: Evolution; International Journal of Organic Evolution
P S Sidhu
In these days of political vagueness, to use a kinder term, although many would describe the situation as turmoil, in Europe, there are success stories to be lauded. Notwithstanding the direction individual countries choose in relation to closer or not so close co-operation in Europe and the direction the political agenda will travel over the next few years, I believe science and in particular medicine has benefited enormously form close co-operation across the European Union and with colleagues outside this political and trading block of nations...
October 2016: Ultraschall in der Medizin
Vipan K Parihar, Barrett D Allen, Chongshan Caressi, Stephanie Kwok, Esther Chu, Katherine K Tran, Nicole N Chmielewski, Erich Giedzinski, Munjal M Acharya, Richard A Britten, Janet E Baulch, Charles L Limoli
The Mars mission will result in an inevitable exposure to cosmic radiation that has been shown to cause cognitive impairments in rodent models, and possibly in astronauts engaged in deep space travel. Of particular concern is the potential for cosmic radiation exposure to compromise critical decision making during normal operations or under emergency conditions in deep space. Rodents exposed to cosmic radiation exhibit persistent hippocampal and cortical based performance decrements using six independent behavioral tasks administered between separate cohorts 12 and 24 weeks after irradiation...
October 10, 2016: Scientific Reports
Liulin Deng, Yehia M Ibrahim, Sandilya V B Garimella, Ian K Webb, Ahmed M Hamid, Randolph V Norheim, Spencer A Prost, Jeremy A Sandoval, Erin S Baker, Richard D Smith
The initial use of traveling waves (TW) for ion mobility (IM) separations using structures for lossless ion manipulations (SLIM) employed an ion funnel trap (IFT) to accumulate ions from a continuous electrospray ionization source and was limited to injected ion populations of ∼10(6) charges due to the onset of space charge effects in the trapping region. Additional limitations arise due to the loss of resolution for the injection of ions over longer periods, such as in extended pulses. In this work a new SLIM "flat funnel" (FF) module has been developed and demonstrated to enable the accumulation of much larger ion populations and their injection for IM separations...
October 7, 2016: Analytical Chemistry
Mohammad Zare Mehrjardi, Elham Keshavarz, Andrea Poretti, Adriano N Hazin
Zika virus (ZIKV) is an arbovirus from the Flaviviridae family. It is usually transmitted by mosquito bite. There have been no reports of severe symptoms caused by ZIKV infection up until the last few years. In October 2013 an outbreak was reported in French Polynesia with severe neurological complications in some affected cases. In November 2015, the Ministry of Health of Brazil attributed the increased number of neonatal microcephaly cases in northeastern Brazil to congenital ZIKV infection. The rapid spread of the virus convinced the World Health Organization to announce ZIKV infection as a "Public Health Emergency of International Concern" in February 2016...
October 6, 2016: Japanese Journal of Radiology
Steve Hankey, Greg Lindsey, Julian D Marshall
BACKGROUND: Providing infrastructure and land uses to encourage active travel (i.e., bicycling and walking) are promising strategies for designing health-promoting cities. Population-level exposure to air pollution during active travel is understudied. OBJECTIVES: To (1) investigate population-level patterns in exposure during active travel, based on spatial estimates of bicycle traffic, pedestrian traffic, and particulate concentrations; and, (2) assess how those exposure patterns are associated with the built environment...
October 7, 2016: Environmental Health Perspectives
Cara L Benjamin, Raymond P Stowe, Lisa St John, Clarence F Sams, Satish K Mehta, Brian E Crucian, Duane L Pierson, Krishna V Komanduri
Following the advent of molecular assays that measure T cell receptor excision circles (TRECs) present in recent thymic emigrants, it has been conclusively shown that thymopoiesis persists in most adults, but that functional output decreases with age, influencing the maintenance of a diverse and functional T cell receptor (TCR) repertoire. Space flight has been shown to result in a variety of phenotypic and functional changes in human T cells and in the reactivation of latent viruses. While space flight has been shown to influence thymic architecture in rodents, thymopoiesis has not previously been assessed in astronauts...
August 4, 2016: JCI Insight
Dawn C Mackey, Li-Yung Lui, Peggy M Cawthon, Kristine Ensrud, Kristine Yaffe, Steven R Cummings
OBJECTIVES: To evaluate the relationship between life-space mobility (extent, frequency, independence of movement) and mortality in older women. DESIGN: Prospective cohort study. SETTING: Four U.S. clinical sites. PARTICIPANTS: Women (N = 1,498) aged 75 to 102 (mean 87.6) followed from 2006 to 2015. MEASUREMENTS: Life-space during the past 4 weeks was assessed in an interview, scored from 0 (daily restriction to bedroom) to 120 (daily trips outside town without assistance), and categorized (0-20, 21-40, 41-60, 61-80, 81-120)...
October 3, 2016: Journal of the American Geriatrics Society
Jenifer N Saldanha, Santosh Pandey, Jo Anne Powell-Coffman
As we seek to recognize the opportunities of advanced aerospace technologies and spaceflight, it is increasingly important to understand the impacts of hypergravity, defined as gravitational forces greater than those present on the earth's surface. The nematode Caenorhabditis elegans has been established as a powerful model to study the effects of altered gravity regimens and has displayed remarkable resilience to space travel. In this study, we investigate the effects of short-term and defined hypergravity exposure on C...
August 2016: Life Sciences in Space Research
Alicia M McConnell, Bindu Konda, David G Kirsch, Barry R Stripp
Exposure to high-linear energy transfer (LET) radiation occurs in a variety of situations, including charged particle radiotherapy, radiological accidents, and space travel. However, the extent of normal tissue injury in the lungs following high-LET radiation exposure is unknown. Here we show that exposure to high-LET radiation led to a prolonged loss of in vitro colony forming ability by airway epithelial progenitor cells. Furthermore, exposure to high-LET radiation induced clonal expansion of a subset of progenitor cells in the distal airway epithelium...
2016: Scientific Reports
Himanshu Khurana, Yatin Mehta, Sunil Dubey
BACKGROUND AND AIMS: Long distance air travel for medical needs is on the increase worldwide. The condition of some patients necessitates specially modified aircraft, and monitoring and interventions during transport by trained medical personnel. This article presents our experience in domestic and international interhospital air medical transportation from January 2010 to January 2014. MATERIAL AND METHODS: Hospital records of all air medical transportation undertaken to the institute during the period were analyzed for demographics, primary etiology, and events during transport...
July 2016: Journal of Anaesthesiology, Clinical Pharmacology
Shannon Hateley, Ravikumar Hosamani, Shilpa R Bhardwaj, Lior Pachter, Sharmila Bhattacharya
Altered gravity can perturb normal development and induce corresponding changes in gene expression. Understanding this relationship between the physical environment and a biological response is important for NASA's space travel goals. We use RNA-Seq and qRT-PCR techniques to profile changes in early Drosophila melanogaster pupae exposed to chronic hypergravity (3g, or three times Earth's gravity). During the pupal stage, D. melanogaster rely upon gravitational cues for proper development. Assessing gene expression changes in the pupae under altered gravity conditions helps highlight gravity-dependent genetic pathways...
September 10, 2016: Genomics
Esra Yuce, Gulperi Koçer, Turan Atila Çini
Aerospace medicine is the medical discipline responsible for assessing and conserving the health, safety, and performance of individuals involved in air and space travel. With the upward trend in airline travel, flight-related oral conditions requiring treatment have become a source of concern for aircrew members. Awareness and treatment of any potential physiological problems for these aircrews have always been critical components of aviation safety. In a flight situation, oral and maxillofacial problems may in fact become life-threatening clinical conditions...
September 2016: General Dentistry
Nicolas Clabaux, Jean-Yves Fournier, Jean-Emmanuel Michel
OBJECTIVE: The objective of this study is to estimate the crash risk per kilometer travelled by powered two wheeler riders filtering through traffic on urban roads. METHODS: Using the traffic injury crashes recorded by the police over a period of three years on fourteen sections of urban roads in the city of Marseille, France and a campaign of observations of powered two-wheelers, the crash risk per kilometer travelled by powered two-wheelers filtering was estimated and compared to the risk of powered two-wheelers that did not filter...
September 2, 2016: Traffic Injury Prevention
M Banerjee, V Volpert
The prey-predator model with nonlocal consumption of prey introduced in this work extends previous studies of local reaction-diffusion models. Linear stability analysis of the homogeneous in space stationary solution and numerical simulations of nonhomogeneous solutions allow us to analyze bifurcations and dynamics of stationary solutions and of travelling waves. These solutions present some new properties in comparison with the local models. They correspond to different feeding strategies of predators observed in ecology...
August 2016: Chaos
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