keyword
https://read.qxmd.com/read/38492615/the-impact-of-frailty-as-a-critical-mediator-causing-postoperative-neurocognitive-disorders-in-postoperative-cardiac-patients
#21
REVIEW
Hu Li, Jinfeng Li, Xin Huang, Bhushan Sandeep, Jing Yang
Frailty is prevalent in elderly cardiac patients and may be a critical predictor of post-operative neurocognitive disorders (PND). The aim of this review was to demonstrate the correlation of frailty with PND in postsurgical elder patients. A review of published literature and bibliometric analysis was undertaken. Electronic databases from 2009 to 2022 were searched to identify articles that evaluated the relationship between frailty and PND in aging populations. Demographic data, type of surgery performed, frailty measurement, and impact of frailty on PND were extracted from the selected studies...
March 14, 2024: Current Problems in Cardiology
https://read.qxmd.com/read/38488063/quality-of-life-in-patients-with-severe-aortic-stenosis-undergoing-transcatheter-aortic-valve-implantation-tools-and-evidence
#22
REVIEW
Crina-Ioana Radulescu, Angelica Cersosimo, Mauro Massussi, Andrea Laurito, Marco Metra, Ovidiu Chioncel, Marianna Adamo
Aortic stenosis is the most prevalent valvular heart disease requiring intervention, especially in the elderly population. Surgical aortic valve replacement and transcatheter aortic valve implantation (TAVI) are well established treatment options for symptomatic patients with severe aortic stenosis, as they provide a significant survival benefit. Aortic stenosis may have an important impact on patients' quality of life (QoL). However, advanced age, comorbidities and frailty may limit the beneficial effect of aortic stenosis interventions in terms of QoL...
April 1, 2024: Journal of Cardiovascular Medicine
https://read.qxmd.com/read/38486469/evaluation-of-factors-influencing-handgrip-strength-asymmetry-in-elderly-peruvians
#23
JOURNAL ARTICLE
Alba Zevallos, Renzo Pajuelo-Vásquez, Kiara Camacho-Caballero, Rodrigo Corcuera-Ciudad, Paola Goicochea-Romero, Wendy Gutiérrez-Baca, Diego Chambergo-Michilot, José F Parodi, Fernando M Runzer-Colmenares
BACKGROUND: Sarcopenia is a musculoskeletal disease involving the reduction of muscle mass, strength, and performance. Handgrip strength (HGS) measurements included in frailty assessments are great biomarkers of aging and are related to functional deficits. We assessed the association between potential influencing factors and HGS asymmetry in older Peruvian adults. METHODS: We used a database of the Peruvian Naval Medical Center "Cirujano Santiago Távara" located in Callao, Peru...
March 15, 2024: Annals of geriatric medicine and research
https://read.qxmd.com/read/38474849/a-herbal-prescription-of-insamyangyeongtang-as-a-therapeutic-agent-for-frailty-in-elderly-a-narrative-review
#24
REVIEW
Han-Gyul Lee, Ichiro Arai, Seungwon Kwon
Frailty is a major geriatric syndrome with a multifactorial etiology that induces a decline in multiple physiological and psychological functions. In traditional East Asian medicine (TEAM), qi and blood deficiency clinically represent as fatigue, anemia, anorexia, decreased strength after illness, and weakness, commonly interpretated as frailty. An herbal prescription of Insamyangyeongtang (IYT, Ninjin'yoeito in Japanese, Ren-Shen-Yang-Rong-Tang in Chinese) tonifies qi and blood and has the potential to treat multiple targets caused by qi and blood deficiency...
March 1, 2024: Nutrients
https://read.qxmd.com/read/38474844/assessing-muscle-mass-in-the-orthopedic-clinical-setting-application-of-the-ultrasound-sarcopenia-index-in-elderly-subjects-with-a-recent-femoral-fracture
#25
JOURNAL ARTICLE
Luca Di Lenarda, Alex Buoite Stella, Chiara Ratti, Luca Ruggiero, Monica Bernard, Luisa Priscamaria Cavarzerani, Gianluca Canton, Luigi Murena
BACKGROUND: Sarcopenia poses a risk factor for falls, disability, mortality, and unfavorable postoperative outcomes. Recently, the Ultrasound Sarcopenia Index (USI) has been validated to assess muscle mass, and this study aimed to apply the USI in the clinical setting. METHODS: This prospective observational study included 108 patients aged >65 years, hospitalized for proximal femoral traumatic fracture. Patients were divided into two groups based on anamnestic data: patients with independent walking (IW) and patients requiring walking aid (WA) before admission...
February 29, 2024: Nutrients
https://read.qxmd.com/read/38469806/ercp-for-common-bile-duct-stones-in-the-elderly-refine-the-procedure-to-improve-outcomes
#26
JOURNAL ARTICLE
Jesús García-Cano, Miriam Viñuelas Chicano, Laura Valiente González
Removal of common bile duct stones in patients with a previous cholecystectomy was one of the first indications for ERCP with biliary sphincterotomy. Thanks to a minimally invasive procedure, patients were prevented from having a new operation. Subsequently, as the technique proved to be successful, ERCP was extended to all patients with choledocholithiasis, regardless of whether or not they had gallbladder. Also contributing was the fact that, at least in the beginnings, surgical interventions on the bile duct with laparoscopic cholecystectomy were more difficult...
March 12, 2024: Revista Española de Enfermedades Digestivas
https://read.qxmd.com/read/38458385/the-impact-of-patient-reported-frailty-on-cardiovascular-outcomes-in-elderly-patients-after-non-st-acute-coronary-syndrome
#27
JOURNAL ARTICLE
W W A van den Broek, M E Gimbel, R S Hermanides, C Runnett, R F Storey, P Knaapen, M E Emans, R M Oemrawsingh, J Cooke, G Galasko, R Walhout, M G Stoel, C von Birgelen, Paul F M M van Bergen, S L Brinckman, I Aksoy, A Liem, A W J Van't Hof, J W Jukema, A A C M Heestermans, D Nicastia, H Alber, D Austin, A Nasser, V Deneer, J M Ten Berg
BACKGROUND: As life expectancy increases, the population of older individuals with coronary artery disease and frailty is growing. We aimed to assess the impact of patient-reported frailty on the treatment and prognosis of elderly early survivors of non-ST-elevation acute coronary syndrome (NSTE-ACS). METHODS: Frailty data were obtained from two prospective trials, POPular Age and the POPular Age Registry, which both assessed elderly NSTE-ACS patients. Frailty was assessed one month after admission with the Groningen Frailty Indicator (GFI) and was defined as a GFI-score of 4 or higher...
March 7, 2024: International Journal of Cardiology
https://read.qxmd.com/read/38456903/-drug-therapy-for-arterial-hypertension-and-atrial-fibrillation-in-frail-patients-are-there-any-new-insights-and-recommendations
#28
REVIEW
Ursula Müller-Werdan
The frail and elderly are considered to be at particular risk of suffering an adverse drug reaction. Empirical studies confirm the increased rate of adverse drug reactions. Whether frailty per se impairs drug metabolism or the underlying organ ageing processes and multimorbidity cannot be answered with certainty based on current data. Cardiovascular diseases exhibit a considerable interdependence with frailty. For example, there is a disproportionate syndromal interdependence between heart failure and frailty, and the typical ageing processes of the sinus node can be interpreted as heartbeat frailty...
March 8, 2024: Inn Med (Heidelb)
https://read.qxmd.com/read/38454293/frailty-of-the
#29
JOURNAL ARTICLE
Tadashi Kitahara, Tomoyuki Shiozaki, Hiroshi Hosoi
Vestibular frailty and presbyvestibulopathy, including benign paroxysmal positional vertigo (BPPV), can cause dizziness among elderly patients. Vestibular frailty and presbyvestibulopathy may contribute to the onset of the vicious circle of falling-bone fracture-prolonged bedridden status-senile dementia. Treatment interventions for vestibular frailty and presbyvestibulopathy should be based on vestibular rehabilitation rather than vestibular implantation or regeneration. In acute BPPV, the otolith repositioning maneuver can be used to return otolithic debris to the utricle...
January 2024: Journal of International Advanced Otology
https://read.qxmd.com/read/38453311/management-of-the-geriatric-trauma-patient
#30
REVIEW
Megan Elizabeth Lundy, Bo Zhang, Michael Ditillo
With a rapidly aging worldwide population, the care of geriatric trauma patients will be at the forefront of every career in Trauma and Acute Care Surgery. The unique intersection of advanced age, comorbidities, frailty, and physiologic changes presents a challenge in the care of elderly injured patients. It is well established that increasing age is associated with higher mortality and worse outcomes after injury, but it is also clear that there is room for improvement in the management of this special patient population...
April 2024: Surgical Clinics of North America
https://read.qxmd.com/read/38448804/cost-effectiveness-of-prehabilitation-of-elderly-frail-or-pre-frail-patients-prior-to-elective-surgery-praep-go-versus-usual-care-protocol-for-a-health-economic-evaluation-alongside-a-randomized-controlled-trial
#31
JOURNAL ARTICLE
Helene Eckhardt, Wilm Quentin, Julia Silzle, Reinhard Busse, Tanja Rombey
BACKGROUND: Prehabilitation aims to improve patients' functional capacity before surgery to reduce perioperative complications, promote recovery and decrease probability of disability. The planned economic evaluation is performed alongside a large German multi-centre pragmatic, two-arm parallel-group, randomized controlled trial on prehabilitation for frail elderly patients before elective surgery compared to standard care (PRAEP-GO RCT). The aim is to determine the cost-effectiveness and cost-utility of prehabilitation for frail elderly before an elective surgery...
March 6, 2024: BMC Geriatrics
https://read.qxmd.com/read/38445937/society-for-surgery-of-the-alimentary-tract-state-of-the-art-session-2022-frailty-in-surgery
#32
JOURNAL ARTICLE
Deborah S Keller, Cintia M S Kimura, Cindy J Kin, Daniel I Chu, Burke P Smith, Atiya Dhala, Amanda K Arrington, Clancy J Clark, Emily R Winslow, Waddah B Al-Refaie, Puja G Khaitan
Given the exponentially aging population and rising life expectancy in the United States, surgeons are facing a challenging frail population who may require surgery but may not qualify based on their general fitness. There is an urgent need for greater awareness of the importance of frailty measurement and the implementation of universal assessment of frail patients into clinical practice. Pairing risk stratification with stringent protocols for prehabilitation and minimally invasive surgery and appropriate enhanced recovery protocols could optimize and condition frail patients before, during, and immediately after surgery to mitigate postoperative complications and consequences on patient function and quality of life...
February 2024: Journal of Gastrointestinal Surgery
https://read.qxmd.com/read/38440850/preoperative-geriatric-assessment-of-urological-patients-a-narrative-review
#33
JOURNAL ARTICLE
Marcus Köller
PURPOSE OF REVIEW: The proportion of older people is increasing disproportionately. The age between 60 and 65 years is seen as the transition to 'old age'. Frailty is a risk factor for morbidity, mortality, and complications in the context of medical interventions or adverse effects of drug therapies. One of the core components of frailty, the age-related loss of muscle mass, is sarcopenia. Is there an influence of frailty, as well as sarcopenia and some other aspects, i.e. malnutrition, on the outcome in elderly urologic patients? RECENT FINDINGS: These phenomena of aging correlate with the incidence postoperative complication, infections, readmission rates or mortality...
March 5, 2024: Current Opinion in Urology
https://read.qxmd.com/read/38439017/unraveling-the-relationship-between-high-sensitivity-c-reactive-protein-and-frailty-evidence-from-longitudinal-cohort-study-and-genetic-analysis
#34
JOURNAL ARTICLE
Yu-Feng Luo, Zi-Jian Cheng, Yan-Fei Wang, Xi-Yuan Jiang, Shu-Feng Lei, Fei-Yan Deng, Wen-Yan Ren, Long-Fei Wu
BACKGROUND: This study aimed to investigate the association of high-sensitivity C-reactive protein (hs-CRP) with incident frailty as well as its effects on pre-frailty progression and regression among middle-aged and older adults. METHODS: Based on the frailty index (FI) calculated with 41 items, 6890 eligible participants without frailty at baseline from China Health and Retirement Longitudinal Study (CHARLS) were categorized into health, pre-frailty, and frailty groups...
March 4, 2024: BMC Geriatrics
https://read.qxmd.com/read/38437611/meals-on-wheels-clients-measurable-differences-in-the-likelihood-of-aging-in-place-or-being-hospitalized
#35
JOURNAL ARTICLE
Sarah E Walsh, France Marie Weaver, Jennifer Chubinski
Little is known about how participation in home-delivered meal programs (known as Meals on Wheels), financed in part through the Older Americans Act, relates to the use of health services and the ability to age in place for elder Medicare beneficiaries. Using 2013-20 data from the National Health and Aging Trends Study, we evaluated the relationship between Meals on Wheels use and two outcomes-likelihood of continued community residence and risk for hospitalization-in the following year for Medicare beneficiaries ages sixty-five and older, overall and by gender, race, Medicaid enrollment, and frailty...
March 2024: Health Affairs
https://read.qxmd.com/read/38436303/connecting-cohorts-of-finnish-biobanks-creates-a-research-resource-for-the-study-of-healthy-ageing
#36
JOURNAL ARTICLE
Niina Eklund, Salla-Maaria Pätsi, Heli Lehtiniemi, Samppa Rohkimainen, Juha Kivelä, Hanna Öhman, Minttu Sauramo, Kyösti Sutinen, Anja Keskinarkaus, Perttu Terho, Tapio Seppänen, Pia Nyberg, Minna Männikkö, Kaisa Silander
AIMS: Connecting cohorts with biobanks is a Finnish biobank collaboration, creating an infrastructure for the study of healthy ageing. We aimed to develop a model for data integration and harmonisation between different biobanks with procedures for joint access. METHODS: The heart of the collaboration is the integrated datasets formed by using data from three biobanks: (a) Arctic Biobank, hosting regional birth cohorts and cohorts of elderly; (b) hospital-affiliated Borealis Biobank of Northern Finland; and (c) THL Biobank, hosting population-based cohorts...
March 4, 2024: Scandinavian Journal of Public Health
https://read.qxmd.com/read/38435451/cardiovascular-disease-in-the-older-adult-where-are-we-4-decades-later
#37
JOURNAL ARTICLE
Farshad Forouzandeh, Karen Alexander, Daniel Forman, James N Kirkpatrick, Michael W Rich, Susan Zieman, Nanette K Wenger
The 1986 Bethesda Conference on Cardiovascular Disease (CVD) in the Elderly, co-chaired by Drs. Nanette Wenger, Frank Marcus, and Robert O'Rourke, delineated the anticipated social, political, ethical, economic and technological impact of an aging population on the incidence, prevalence, and management of CVD in the US and worldwide. In the ensuing 4 decades, older patients have come to comprise an increasingly large proportion of the CVD population, and there has been an explosion of research in all aspects of CVD affecting older adults...
February 2024: JACC Adv
https://read.qxmd.com/read/38433882/frailty-seasonal-sensitivity-and-health-related-quality-of-life-in-older-people-living-in-high-southern-latitudes-a-bayesian-analysis
#38
JOURNAL ARTICLE
Diego Mabe-Castro, Karen Tobar Gomez, Matías Castillo-Aguilar, Sebastián Jannas-Vela, Eduardo Guzmán-Muñoz, Pablo Valdés-Badilla, Cristian Núñez-Espinosa
BACKGROUND: In older people, a notable research gap exists regarding the intricate dynamics between frailty, seasonal sensitivity, and health-related quality of life (HRQoL). This study aimed to determine the association between frailty, seasonal sensitivity, and HRQoL in older people from high southern latitudes. METHODS: A cross-sectional observational study was conducted. Frailty, seasonal sensitivity, and HRQoL measurements were self-reported by participants through questionnaires...
March 2024: Canadian Geriatrics Journal: CGJ
https://read.qxmd.com/read/38429115/geriatric-screening-and-comprehensive-geriatric-assessment-during-initial-oncology-appointments
#39
JOURNAL ARTICLE
Tânia Madureira, Joana Magalhães, Pedro Vilas, Elsa Campôa, Paulo Luz, Filipe Coutinho
INTRODUCTION: Geriatric oncology underscores the significance of assessing functional age in guiding medical decisions, endeavouring to delineate practical and efficacious methodologies for evaluating functionality, adapting therapeutic regimens and attenuating the risks of treatment-related deterioration. OBJECTIVES AND METHODS: In this prospective study, we aimed to delineate the characteristics of older patients presenting for their initial oncology appointment by using geriatric screening (G8 score) and comprehensive geriatric assessment (CGA), while also assessing the feasibility of these evaluations...
March 1, 2024: BMJ Supportive & Palliative Care
https://read.qxmd.com/read/38429051/burns-in-the-elderly
#40
REVIEW
Lux Shah, Audra T Clark, Jessica Ballou
Burns in the elderly are a significant cause of morbidity and mortality. Frailty is an important indicator of patient health and physiologic reserve. Comorbidities and typical age-related changes significantly impact the outcomes of elderly burn patients and decisions made during their burn care. It is essential to have early and thorough discussions about the goals of care and rehabilitation plans. Physiologic changes that occur from aging cause slower wound healing and may make operative treatment more challenging, although techniques such as autographing, skin substitutes, and flaps may all play a role in treating this patient population...
April 2024: Clinics in Plastic Surgery
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