keyword
https://read.qxmd.com/read/38360176/impact-of-skin-cancer-screening-on-melanoma-thickness-and-stage
#21
JOURNAL ARTICLE
Claudia Morr, Taylor Jade Prechtel, Rachel Hardacker, Maria Bell, James E Slaven, Syril Keena T Que
No abstract text is available yet for this article.
February 13, 2024: Journal of the American Academy of Dermatology
https://read.qxmd.com/read/38349690/-the-actual-issues-of-improvement-of-organization-of-screening-of-skin-neoplasms-in-out-patient-conditions
#22
JOURNAL ARTICLE
M V Gusarov, B M Tayts, A N Barinova
The skin malignant neoplasms constitute one of significant problems of public health. The increasing of morbidity and mortality of melanoma and other types of skin cancers is registered. The early detection of disease assures mortality decreasing and increases survival of patients. The purpose of the study is to develop optimal model of organizational and preventive measures of early diagnostic of malignant skin tumors. The comprehensive study was carried out, which included assessment of survey of patients using questionnaire "Melanoma Diagnosis Day"...
January 2024: Problemy Sot︠s︡ialʹnoĭ Gigieny, Zdravookhranenii︠a︡ i Istorii Medit︠s︡iny
https://read.qxmd.com/read/38342916/cancer-patterns-in-iran-a-gender-specific-spatial-modelling-of-cancer-incidence-during-2014-2017
#23
JOURNAL ARTICLE
Sharareh Faramarzi, Behzad Kiani, Shahla Faramarzi, Neda Firouraghi
BACKGROUND: Cancer is a significant public health concern and the second leading cause of death. This study aims to visualize spatial patterns of top common cancer types and identify high-risk and low-risk counties for these cancers in Iran from 2014 to 2017. METHODS: In this study, we analyzed 482,229 newly diagnosed cancer cases recorded by the Iranian National Population-Based Cancer Registry from 2014 to 2017. We employed a purely spatial scanning model and local Moran I analysis to explore spatial patterns across Iran...
February 12, 2024: BMC Cancer
https://read.qxmd.com/read/38339380/artificial-intelligence-applied-to-non-invasive-imaging-modalities-in-identification-of-nonmelanoma-skin-cancer-a-systematic-review
#24
REVIEW
Emilie A Foltz, Alexander Witkowski, Alyssa L Becker, Emile Latour, Jeong Youn Lim, Andrew Hamilton, Joanna Ludzik
BACKGROUND: The objective of this study is to systematically analyze the current state of the literature regarding novel artificial intelligence (AI) machine learning models utilized in non-invasive imaging for the early detection of nonmelanoma skin cancers. Furthermore, we aimed to assess their potential clinical relevance by evaluating the accuracy, sensitivity, and specificity of each algorithm and assessing for the risk of bias. METHODS: Two reviewers screened the MEDLINE, Cochrane, PubMed, and Embase databases for peer-reviewed studies that focused on AI-based skin cancer classification involving nonmelanoma skin cancers and were published between 2018 and 2023...
February 1, 2024: Cancers
https://read.qxmd.com/read/38330217/ethical-considerations-for-artificial-intelligence-in-dermatology-a-scoping-review
#25
JOURNAL ARTICLE
Emily R Gordon, Megan H Trager, Despina Kontos, Chunhua Weng, Larisa J Geskin, Lydia S Dugdale, Faramarz H Samie
The field of dermatology is experiencing the rapid deployment of artificial intelligence (AI), from mobile applications for skin cancer detection to large language models like ChatGPT that can answer generalist or specialist questions about skin diagnoses. With these new applications, ethical concerns have emerged. In this scoping review, we aim to identify the applications of AI to the field of dermatology and to understand their ethical implications. We utilized a multifaceted search approach, searching PubMed, Medline, Cochrane, and Google Scholar for primary literature according to the Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) Extension for Scoping Reviews...
February 8, 2024: British Journal of Dermatology
https://read.qxmd.com/read/38328458/recurrent-colon-cancer-in-a-patient-with-muir-torre-syndrome-a-case-report
#26
Angeline C Rivkin, Philip Bystrom, Amy Y Lin, Vivek Chaudhry
Muir-Torre syndrome (MTS) is a rare subtype of hereditary nonpolyposis colorectal cancer syndrome caused by a defect in DNA mismatch repair leading to microsatellite instability. It is characterized by the presence of at least one sebaceous gland tumor and one internal malignancy, most commonly colorectal and endometrial tumors. These patients have a high propensity for tumorigenesis, and while strict screening protocols are in place, there are only two cases that describe the management approach to recurrent colon cancer...
February 2024: Journal of Surgical Case Reports
https://read.qxmd.com/read/38326693/inhibitory-effects-of-bioactive-compounds-on-uvb-induced-photodamage-in-human-keratinocytes-modulation-of-mmp1-and-wnt-signaling-pathways
#27
JOURNAL ARTICLE
Meiling Liu, Shaokai Huang, Sunmin Park
UVB radiation significantly threatens skin health, contributing to wrinkle formation and an elevated risk of skin cancer. This study aimed to explore bioactive compounds with potential UVB-protective properties. Using in silico analysis, we chose compounds to reduce binding energy with matrix metalloproteinase-1 (MMP1). Piperitoside, procyanidin C1, and mulberrofuran E emerged as promising candidates through this computational screening process. We investigated the UVB-protective efficacy of the selected compounds and underlying mechanisms in human immortalized keratinocytes (HaCaT)...
February 7, 2024: Photochemical & Photobiological Sciences
https://read.qxmd.com/read/38323537/the-state-of-artificial-intelligence-in-skin-cancer-publications
#28
JOURNAL ARTICLE
Maxine Joly-Chevrier, Anne Xuan-Lan Nguyen, Laurence Liang, Michael Lesko-Krleza, Philippe Lefrançois
BACKGROUND: Artificial intelligence (AI) in skin cancer is a promising research field to assist physicians and to provide support to patients remotely. Physicians' awareness to new developments in AI research is important to define the best practices and scope of integrating AI-enabled technologies within a clinical setting. OBJECTIVES: To analyze the characteristics and trends of AI skin cancer publications from dermatology journals. METHODS: AI skin cancer publications were retrieved in June 2022 from the Web of Science...
February 7, 2024: Journal of Cutaneous Medicine and Surgery
https://read.qxmd.com/read/38323503/skin-cancer-screening-the-experience-in-south-portugal
#29
JOURNAL ARTICLE
José A Maximino, Alexandra Mayer, António Lourenço, Rui O Soares, Marta Pojo
BACKGROUND: The number of skin cancer cases and related deaths continues to increase worldwide, including in Portugal. The lack of efficient health care leaves the southern Portuguese population at risk of presenting skin lesions at later stages. An initiative for skin cancer screening and medical care follow-up was created by the nonprofit organization Liga Portuguesa Contra o Cancro - Núcleo Regional do Sul (LPCC-NRS). METHODS: Information was gathered from 4,398 participants in several Southern Portugal regions, from January 2021 to July 2022...
February 7, 2024: International Journal of Dermatology
https://read.qxmd.com/read/38288775/skin-cancer-prevention-in-extreme-sports-intervention-in%C3%A2-a%C3%A2-24-h-race
#30
JOURNAL ARTICLE
Alba Rodríguez Martínez, Carmen Vaz Pardal, José Aguilera Arjona, Francisco Rivas Ruiz, Diego Doncel Molinero, Manuel Ruiz Paulano, Andras Subert, Jose Vicente Gutiérrez Manzanedo, Jacobo Cambil Martín, Maria Victoria de Gálvez Aranda, Leocricia Jiménez López, Nuria Blázquez Sánchez, Magdalena de Troya Martín
INTRODUCTION: Excessive sun exposure and sunburns are the main preventable causes of skin cancer. The growing popularity of outdoor sports in developed countries has motivated the objective of this work to study the risk of photoexposure and the skin cancer prevention needs of athletes in an extreme race and evaluate an intervention targeted at this population. METHODS: An observational study was conducted during the XXIII edition of the 101 km de Ronda race, which consisted of trail running and mountain biking categories...
January 2024: Photodermatology, Photoimmunology & Photomedicine
https://read.qxmd.com/read/38288311/patterns-of-metastatic-spread-and-tumor-burden-in-unselected-cancer-patients-using-pet-imaging-implications-for-the-oligometastatic-spectrum-theory
#31
JOURNAL ARTICLE
Sebastian M Christ, Kaspar Pohl, Jonas Willmann, Philip Heesen, Astrid Heusel, Maiwand Ahmadsei, Anja Kühnis, Eugenia Vlaskou Badra, Urs J Muehlematter, Michael Mayinger, Panagiotis Balermpas, Nicolaus Andratschke, Nicholas Zaorsky, Martin Huellner, Matthias Guckenberger
INTRODUCTION AND BACKGROUND: Metastatic disease has been proposed as a continuum, with no clear cut-off between oligometastatic and polymetastatic disease. This study aims to quantify tumor burden and patterns of spread in unselected metastatic cancer patients referred for PET-based staging, response assessment of restaging. MATERIALS AND METHODS: All oncological fluorodeoxyglucose (FDG-) and prostate-specific membrane antigen (PSMA-) positron emission tomography (PET) scans conducted at a single academic center in 2020 were analyzed...
March 2024: Clinical and Translational Radiation Oncology
https://read.qxmd.com/read/38282244/exposome-and-basal-cell-carcinoma-a-multicenter-case-control-study
#32
JOURNAL ARTICLE
Alba Navarro-Bielsa, Tamara Gracia-Cazaña, Manuel Almagro, Sonia De-la-Fuente-Meira, Ángeles Florez, Oriol Yélamos, Trinidad Montero-Vilchez, Carlos González-Cruz, Adrián Diago, Isabel Abadías-Granado, Victoria Fuentelsaz, María Colmenero, Jose Bañuls, Salvador Arias-Santiago, Agustín Buendía-Eisman, Manuel Almenara-Blasco, Pedro Gil-Pallares, Yolanda Gilaberte
BACKGROUND: While ultraviolet radiation (UVR) present in sunlight is recognized as the main etiological agent of skin cancer, the most frequent form of which is basal cell carcinoma (BCC), other exposome factors like pollution, diet, and lifestyle may also contribute. This study aimed to investigate the association of BCC and exposome-related factors in the Spanish population. METHODS: BCC cases (n = 119) and controls (n = 127) with no history of skin cancer were recruited between April 2020 and August 2022 by 13 dermatologists throughout Spain in this prospective multicenter case-control study...
January 28, 2024: International Journal of Dermatology
https://read.qxmd.com/read/38276640/insights-on-the-uv-screening-potential-of-marine-inspired-thiol-compounds
#33
JOURNAL ARTICLE
Alessia Luccarini, Annalisa Zuccarotto, Roberta Galeazzi, Camilla Morresi, Mariorosario Masullo, Immacolata Castellano, Elisabetta Damiani
One of the major threats to skin aging and the risk of developing skin cancer is excessive exposure to the sun's ultraviolet radiation (UVR). The use of sunscreens containing different synthetic, organic, and inorganic UVR filters is one of the most widespread defensive measures. However, increasing evidence suggests that some of these compounds are potentially eco-toxic, causing subtle damage to the environment and to marine ecosystems. Resorting to natural products produced in a wide range of marine species to counteract UVR-mediated damage could be an alternative strategy...
December 19, 2023: Marine Drugs
https://read.qxmd.com/read/38262229/relationship-between-climate-change-and-skin-cancer-and-implications-for-prevention-and-management-a-scoping-review
#34
REVIEW
T P G Watson, M Tong, J Bailie, K Ekanayake, R S Bailie
OBJECTIVES: This study aimed to explore the published research on the relationship between climate change and skin cancer and the implications for prevention, management and further research. STUDY DESIGN: Scoping review. METHODS: This scoping review following JBI methodology reviewed English articles identified in searches of MEDLINE, Embase, CINAHL, Web of Science and Scopus on 14 April 2023. The screening of articles was completed by two independent reviewers...
January 22, 2024: Public Health
https://read.qxmd.com/read/38255727/recent-updates-regarding-the-antiproliferative-activity-of-galium-verum-extracts-on-a375-human-malignant-melanoma-cell-line
#35
JOURNAL ARTICLE
Alexandra-Denisa Semenescu, Elena-Alina Moacă, Andrada Iftode, Cristina-Adriana Dehelean, Diana-Simona Tchiakpe-Antal, Laurian Vlase, Slavita Rotunjanu, Delia Muntean, Sorin Dan Chiriac, Raul Chioibaş
The biological activity of Galium verum herba was exerted on various tumor cell lines with incredible results, but their potential effect on malignant melanoma has not been established yet. Therefore, the current study was structured in two directions: (i) the investigation of the phytochemical profile of diethyl ether (GvDEE) and butanol (GvBuOH) extracts of G. verum L. and (ii) the evaluation of their biological profile on A375 human malignant melanoma cell line. The GvDEE extract showed an FT-IR profile different from the butanol one, with high antioxidant capacity (EC50 of GvDEE = 0...
January 11, 2024: Life
https://read.qxmd.com/read/38248078/multimodal-method-for-differentiating-various-clinical-forms-of-basal-cell-carcinoma-and-benign-neoplasms-in-vivo
#36
JOURNAL ARTICLE
Yuriy I Surkov, Isabella A Serebryakova, Yana K Kuzinova, Olga M Konopatskova, Dmitriy V Safronov, Sergey V Kapralov, Elina A Genina, Valery V Tuchin
Correct classification of skin lesions is a key step in skin cancer screening, which requires high accuracy and interpretability. This paper proposes a multimodal method for differentiating various clinical forms of basal cell carcinoma and benign neoplasms that includes machine learning. This study was conducted on 37 neoplasms, including benign neoplasms and five different clinical forms of basal cell carcinoma. The proposed multimodal screening method combines diffuse reflectance spectroscopy, optical coherence tomography and high-frequency ultrasound...
January 17, 2024: Diagnostics
https://read.qxmd.com/read/38230791/multifaceted-approach-toward-mapping-out-the-anticancer-properties-of-small-molecules-via-in%C3%A2-vitro-evaluation-on-melanoma-and-nonmelanoma-skin-cancer-cells-and-in-silico-target-fishing
#37
JOURNAL ARTICLE
Samuel T Boateng, Tithi Roy, Mercy E Agbo, Md Ashiq Mahmud, Sergette Banang-Mbeumi, Roxane-Cherille N Chamcheu, Rajesh K Yadav, Marion Bramwell, Long K Pham, Danny D Dang, Keith E Jackson, Bolni Marius Nagalo, Ronald A Hill, Tatiana Efimova, Jean Fotie, Jean Christopher Chamcheu
Melanoma and nonmelanoma skin cancers are among the most prevalent and most lethal forms of skin cancers. To identify new lead compounds with potential anticancer properties for further optimization, in vitro assays combined with in-silico target fishing and docking have been used to identify and further map out the antiproliferative and potential mode of action of molecules from a small library of compounds previously prepared in our laboratory. From screening these compounds in vitro against A375, SK-MEL-28, A431, and SCC-12 skin cancer cell lines, 35 displayed antiproliferative activities at the micromolar level, with the majority being primarily potent against the A431 and SCC-12 squamous carcinoma cell lines...
January 2024: Chemical Biology & Drug Design
https://read.qxmd.com/read/38214959/acceptance-of-medical-artificial-intelligence-in-skin-cancer-screening-choice-based-conjoint-survey
#38
JOURNAL ARTICLE
Inga Jagemann, Ole Wensing, Manuel Stegemann, Gerrit Hirschfeld
BACKGROUND: There is great interest in using artificial intelligence (AI) to screen for skin cancer. This is fueled by a rising incidence of skin cancer and an increasing scarcity of trained dermatologists. AI systems capable of identifying melanoma could save lives, enable immediate access to screenings, and reduce unnecessary care and health care costs. While such AI-based systems are useful from a public health perspective, past research has shown that individual patients are very hesitant about being examined by an AI system...
January 12, 2024: JMIR Formative Research
https://read.qxmd.com/read/38213146/total-glucosides-of-paeony-induce-mitochondrial-dysfunction-and-apoptosis-by-promoting-the-degradation-of-%C3%AE-5-nachr-in-melanoma-cells
#39
JOURNAL ARTICLE
Xianguang Meng, Ling Cheng, Jing Jiao, Yuanxin Xing, Li Zhang
BACKGROUND: Malignant melanoma is the leading cause of skin cancer-related death, with high malignancy and rapid progression. Total glucosides of paeony (TGP) are extracted from the roots of Paeonia Lactiflora Pall and are widely used in the treatment of chronic hepatitis, rheumatoid arthritis, and adjuvant therapy of tumor chemotherapy. METHODS: In the present research, M14 and A375 cells were treated with TGP. CCK8, transwell and western blotting were performed to analyze the effect of TGP on cell function...
January 10, 2024: Combinatorial Chemistry & High Throughput Screening
https://read.qxmd.com/read/38204240/the-evolution-of-medical-imaging-in-the-therapeutics-of-patients-with-skin-cancer
#40
JOURNAL ARTICLE
Khushmeen Kaur Brar, Jeba Shiney O, Bhawna Goyal, Ayush Dogra
INTRODUCTION: Medical imaging mechanization has reformed medical management, empowering doctors to recognize cancer prematurely and promote patient outcomes. Imaging tests are of significant influence in the detection and supervision of cancer patients. Cancer recognition generally necessitates imaging studies that, in most instances, utilize a trivial amount of radiation. Methodologies such as X-rays, computed tomography (CT), magnetic resonance imaging (MRI), and positron emission tomography (PET) are predominant in clinical managerial, incorporating remedy and research...
January 10, 2024: Current medical imaging
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