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"Skin cancer" screening

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https://www.readbyqxmd.com/read/28405739/dermatological-comorbidity-in-psoriasis-results-from-a-large-scale-cohort-of-employees
#1
N Zander, I Schäfer, M Radtke, A Jacobi, H Heigel, M Augustin
The field of dermatological comorbidity in psoriasis is only passively explored with contradictory results. Objective of this study was to further investigate the complex field of psoriasis and associated skin diseases by identifying skin comorbidity patterns in an extensive cohort of employees in Germany. Retrospective analysis of data deriving from occupational skin cancer screenings was conducted. From 2001 to 2014 German employees between 16 and 70 years from different branches underwent single whole-body screenings by trained dermatologists in their companies...
April 12, 2017: Archives of Dermatological Research
https://www.readbyqxmd.com/read/28397109/increasing-frequency-of-seborrheic-keratosis-diagnoses-as-a-favorable-consequence-of-teledermatology-based-skin-cancer-screening-a-cross-sectional-study-of-34-553-patients
#2
David Moreno-Ramírez, Jesús Raya-Maldonado, Macarena Morales-Conde, Teresa Ojeda-Vila, Francisco J Martín-Gutiérrez, Andrés Ruíz-de-Casas, Almudena Fernández-Orland, Herrerías-Esteban Jm, Lara Ferrándiz
BACKGROUND: Screening of skin cancer by teledermatology (TD) has improved the early detection of skin cancer by enhancing access to skin cancer clinics. OBJECTIVE: We sought to analyze how TD-based skin cancer screening has changed the frequency of consultations for benign lesions. PATIENTS AND METHODS: A cross-sectional study including teleconsultations received during a 7-year period was conducted to analyze and compare the trendlines of each lesion type over the study period...
April 10, 2017: American Journal of Clinical Dermatology
https://www.readbyqxmd.com/read/28370183/a-network-meta-analysis-of-non-melanoma-skin-cancer-nmsc-treatments-efficacy-and-safety-assessment
#3
Renrong Lv, Qian Sun
The mainstream treatments for non-melanoma skin cancer (NMSC) include photodynamic therapy (PDT), surgery excision (SE), cryotherapy (CT), imiquimod (IM), radiotherapy (RT), 5-fluorouracil (FU) and vehicle (VE). Our network meta-analysis (NMA) was aimed at evaluating the efficacy and safety of these seven treatments and providing superior ones. After searching the trials from Embase and PubMed and screening with our criteria, we conducted the NMA with software R 3.2.3 and STATA 13.0. Complete lesion response (CLR), complete lesion clearance (CLC), cumulative recurrence probabilities (CRP) and adverse effects (AEs) were considered as outcomes and displayed as odds ratios (ORs) and 95% credible intervals (CrI)...
March 29, 2017: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/28353004/the-effectiveness-of-a-population-based-skin-cancer-screening-program-evidence-from-germany
#4
Micha Kaiser, Jörg Schiller, Christopher Schreckenberger
In this paper, we analyze how a nationwide population-based skin cancer screening program (SCS) implemented in Germany in 2008 has impacted the number of hospital discharges following malignant skin neoplasm diagnosis and the malignant melanoma mortality rate per 100,000 inhabitants. Our panel data, drawn from the Eurostat database, cover subregions in 22 European countries, measured at the lowest nomenclature of territorial units for statistics (NUTS) level for 2000-2013. Applying fixed effects methods, we find a significantly positive and robust effect of the German SCS on the number of patients diagnosed with malignant skin neoplasm...
March 28, 2017: European Journal of Health Economics: HEPAC: Health Economics in Prevention and Care
https://www.readbyqxmd.com/read/28342067/the-incidence-of-post-transplant-cancer-among-kidney-transplant-recipients-is-associated-with-the-level-of-tacrolimus-exposure-during-the-first-year-after-transplantation
#5
Shelly Lichtenberg, Ruth Rahamimov, Hefziba Green, Benjamin D Fox, Eytan Mor, Uzi Gafter, Avry Chagnac, Benaya Rozen-Zvi
PURPOSE: Immunosuppressive therapy plays a major role in the development of post-transplant cancer. In this nested case-control study of kidney transplant recipients (KTRs), we investigated whether the incidence of post-transplant cancer is associated with the level of tacrolimus exposure over time. METHODS: We screened the Rabin Medical Center database for adults who received kidney transplants between 2001 and 2014 and developed post-transplant cancer (excluding basal and squamous cell skin cancers)...
March 24, 2017: European Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/28329671/trends-of-skin-cancer-incidence-following-transplantation-in-the-united-states
#6
Sarah T Arron
BackgroundSkin cancer is the most common malignancy occurring after organ transplantation. Although previous research has reported an increased risk of skin cancer in solid organ transplant recipients (OTR), no study has estimated the post-transplant population-based incidence in the US. The objective of this study is to determine the incidence and evaluate the predictors of post-transplant skin cancer, including squamous cell carcinoma (SCC), melanoma (MM), and Merkel cell carcinoma (MCC) in a cohort of US OTR receiving a primary transplant in 2003 or 2008...
September 15, 2016: Dermatology Online Journal
https://www.readbyqxmd.com/read/28329558/integrating-the-integrated-skin-exam-film-into-medical-education
#7
Seth Lofgreen, Michael Lehrer, Paige Bennett, Amit Garg, Cory A Dunnick
AbstractBackgroundThe mortality rate for melanoma continues to rise and the greatest improvement in melanoma survival is attributable to early detection with skin cancer screening exams. However, physicians feel that limited training in the examination of skin and limited clinical time both serve as barriers to adequately assess high-risk lesions.ObjectiveTo test the use of The Integrated Skin Exam film as an instructional tool to teach the examination of skin in a live classroom setting, outside of the purview of the original formal study...
November 15, 2016: Dermatology Online Journal
https://www.readbyqxmd.com/read/28329513/genital-melanoma-are-we-adequately-screening-our-patients
#8
Joseph Zikry, Lance W Chapman, Dorota Z Korta, Janellen Smith
Full-body skin exams (FBSE) play an integral role inearly detection and treatment of skin cancer. Promptdetection of melanoma is especially importantas survival outcomes decrease significantly withpresentation of advanced disease. Given thatmelanoma may grow in areas of skin with little to nosun exposure, genital melanomas are a recognizedentity in cutaneous oncology.
March 15, 2017: Dermatology Online Journal
https://www.readbyqxmd.com/read/28322977/assessment-of-penetration-potential-of-ph-responsive-double-walled-biodegradable-nanogels-coated-with-eucalyptus-oil-for-the-controlled-delivery-of-5-fluorouracil-in-vitro-and-ex-vivo-studies
#9
Prashant Sahu, Sushil K Kashaw, Sanyog Jain, Samaresh Sau, Arun K Iyer
Penetration enhancers coated biodegradable polymeric nanogels loaded with cytotoxic drugs applied via the topical route, can be a promising strategy for improving the chemotherapeutic efficiency of skin cancers. The major objective of proposed research was to investigate the in vitro and ex vivo chemotherapeutic potential of double walled PLGA-chitosan biodegradable nanogel entrapped with 5-fluororuacil (5-FU) coated with eucalyptus oil, topically applied onto the skin. 5-FU was first entrapped in PLGA core by solvent evaporation technique followed by coating with cationic chitosan for ionic interaction with anionic skin cancer cell membrane...
March 18, 2017: Journal of Controlled Release: Official Journal of the Controlled Release Society
https://www.readbyqxmd.com/read/28272243/mobile-teledermatology-for-skin-cancer-screening-a-diagnostic-accuracy-study
#10
Stefan Markun, Nathalie Scherz, Thomas Rosemann, Ryan Tandjung, Ralph P Braun
Skin cancer screening has undoubted potential to reduce cancer-specific morbidity and mortality. Total-body exams remain the prevailing concept of skin cancer screening even if effectiveness and value of this method are controversial. Meanwhile, store and forward teledermatology was shown to be a reliable instrument for several diagnostic purposes mostly in specialized dermatology settings. The objective of this study was to evaluate most convenient mobile teledermatology interventions as instruments for skin cancer screening in a representative population...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28268917/automated-basal-cell-carcinoma-detection-in-high-definition-optical-coherence-tomography
#11
Annan Li, Jun Cheng, Ai Ping Yow, Ruchir Srivastava, Damon Wing Kee Wong, Hong Liang Tey, Jiang Liu
Basal cell carcinoma (BCC) is the most common non-melanoma skin cancer. Conventional diagnosis of BCC requires invasive biopsies. Recently, a high-definition optical coherence tomography (HD-OCT) technique has been developed, which provides a non-invasive in vivo imaging method of skin. Good agreements of BCC features between HD-OCT images and histopathological architecture have been found. Therefore it is possible to automatically detect BCC using HD-OCT. This paper presents a novel BCC detection method that consists of four steps: graph based skin surface segmentation, surface flattening, deep feature extraction and the BCC classification...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28246676/-perception-of-statutory-skin-cancer-screening-in-the-general-population-current-findings-on-participation-knowledge-and-evaluation
#12
L Eissing, I Schäfer, K Strömer, R Kaufmann, A Enk, M Reusch, M Augustin
BACKGROUND: Since 2008, German statutory health insurances offer routine skin cancer screening (rSCS) as a standard benefit. Insured persons aged 35 years and older are eligible for screening every 2 years. OBJECTIVES: The aim of the study was to evaluate perception and utilization of rSCS in the general population. MATERIALS AND METHODS: A representative random sample of n = 1004 adult members of the German statutory health insurances were surveyed by the Forsa Institute via computer-assisted telephone interviews in a cross-sectional study in April 2015...
February 28, 2017: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/28241191/a-large-skin-cancer-screening-quality-initiative-description-and-first-year-outcomes
#13
Laura K Ferris, Melissa I Saul, Yan Lin, Fei Ding, Martin A Weinstock, Alan C Geller, Jian-Min Yuan, Erica Neuren, Spandana Maddukuri, Francis X Solano, John M Kirkwood
Importance: The lack of prospective randomized clinical trials demonstrating that full-body skin examination (FBSE) reduces melanoma morbidity or mortality has prompted an "I" rating from the United States Preventive Services Task Force for population-based skin cancer screening. More data on these screening programs are needed. Objectives: To describe a skin cancer screening quality initiative in a large health care system and to determine if the intervention was associated with screening of a demographically higher-risk population than previous screening programs and if melanoma incidence and thickness differed in screened vs unscreened patients...
February 23, 2017: JAMA Oncology
https://www.readbyqxmd.com/read/28229313/knowledge-and-protective-behaviors-about-skin-cancer-among-nursing-students-in-the-west-black-sea-region-of-turkey
#14
Sevim Çelik, Arzu Ilçe, Işıl Işik Andsoy
Skin cancer is an important health problem worldwide among cancer types and results in death at a minimum level in the case of early diagnosis. Therefore, the application of prevention programs is vital. Nurses by definition take responsibility for programs in prevention, early diagnosis, and screening for cancer. This study was conducted to determine the extent of skin cancer knowledge and protective behaviors among nursing students in the West Black Sea Region of Turkey. This cross-sectional, descriptive study was conducted between February and May 2015...
February 23, 2017: Journal of Cancer Education: the Official Journal of the American Association for Cancer Education
https://www.readbyqxmd.com/read/28227121/automated-basal-cell-carcinoma-detection-in-high-definition-optical-coherence-tomography
#15
Annan Li, Jun Cheng, Ai Ping Yow, Ruchir Srivastava, Damon Wing Kee Wong, Hong Liang Tey, Jiang Liu, Annan Li, Jun Cheng, Ai Ping Yow, Ruchir Srivastava, Damon Wing Kee Wong, Hong Liang Tey, Jiang Liu, Ai Ping Yow, Jiang Liu, Annan Li, Hong Liang Tey, Jun Cheng, Ruchir Srivastava
Basal cell carcinoma (BCC) is the most common non-melanoma skin cancer. Conventional diagnosis of BCC requires invasive biopsies. Recently, a high-definition optical coherence tomography (HD-OCT) technique has been developed, which provides a non-invasive in vivo imaging method of skin. Good agreements of BCC features between HD-OCT images and histopathological architecture have been found. Therefore it is possible to automatically detect BCC using HD-OCT. This paper presents a novel BCC detection method that consists of four steps: graph based skin surface segmentation, surface flattening, deep feature extraction and the BCC classification...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28209049/5-point-checklist-for-skin-cancer-detection-in-primary-care
#16
Elvira Moscarella, Aimilios Lallas, Caterina Longo, Roberto Alfano, Giuseppe Argenziano
BACKGROUND: Skin cancer screening interventions often relay on the involvement of general practitioners (GPs). Many interventions up to now have been directed to training approaches focusing on the clinical features of skin malignancies to increase GPs skill in skin cancer recognition. METHODS: Based on the available current knowledge about skin cancer epidemiology and risk factors, we built up a 5-point checklist to help GPs in triaging patients to be referred to a dermatologist...
February 16, 2017: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/28198377/nmr-metabolic-fingerprints-of-murine-melanocyte-and-melanoma-cell-lines-application-to-biomarker-discovery
#17
Arquimedes Paixão de Santana-Filho, Thiago Jacomasso, Daniel Suss Riter, Andersson Barison, Marcello Iacomini, Sheila Maria Brochado Winnischofer, Guilherme Lanzi Sassaki
Melanoma is the most aggressive type of skin cancer and efforts to improve the diagnosis of this neoplasia are largely based on the use of cell lines. Metabolomics is currently undergoing great advancements towards its use to screening for disease biomarkers. Although NMR metabolomics includes both 1D and 2D methodologies, there is a lack of data in the literature regarding heteronuclear 2D NMR assignments of the metabolome from eukaryotic cell lines. The present study applied NMR-based metabolomics strategies to characterize aqueous and lipid extracts from murine melanocytes and melanoma cell lines with distinct tumorigenic potential, successfully obtaining fingerprints of the metabolites from the extracts of the cell lines by means of 2D NMR HSQC correlation maps...
February 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28195138/bioproduction-characterization-anticancer-and-antioxidant-activities-of-extracellular-melanin-pigment-produced-by-newly-isolated-microbial-cell-factories-streptomyces-glaucescens-neae-h
#18
Noura El-Ahmady El-Naggar, Sara M El-Ewasy
In this present study, a newly isolated strain, Streptomyces sp. NEAE-H, capable of producing high amount of black extracellular melanin pigment on peptone-yeast extract iron agar and identified as Streptomyces glaucescens NEAE-H. Plackett-Burman statistical design was conducted for initial screening of 17 independent (assigned) variables for their significances on melanin pigment production by Streptomyces glaucescens NEAE-H. The most significant factors affecting melanin production are incubation period, protease-peptone and ferric ammonium citrate...
February 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28152736/cancer-depression-and-health-care-coverage-in-the-state-of-nevada-a-retrospective-cross-sectional-study
#19
Manas Agastya, Yaser Dawod, Linha Phan, Mohammad Talha Farooqui, Ji Won Yoo
42 Background: The prevalence of depressive disorders in patients with malignancies is estimated at 20-50%, significantly greater than the general population. Existing literature reports a negative impact of depression on both the patient and their families. There is limited information regarding the impact of healthcare coverage on the prevalence of depression in such patients both in the state of Nevada and nationwide. METHODS: A retrospective cross-sectional study was performed using the Behavioral Risk Surveillance System (BRFSS) database from 2010 to 2014...
March 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28150105/skin-cancer-epidemiology-disease-burden-pathophysiology-diagnosis-and-therapeutic-approaches
#20
REVIEW
Zoe Apalla, Dorothée Nashan, Richard B Weller, Xavier Castellsagué
Skin cancer, including both melanoma and non-melanoma, is the most common type of malignancy in the Caucasian population. Firstly, we review the evidence for the observed increase in the incidence of skin cancer over recent decades, and investigate whether this is a true increase or an artefact of greater screening and over-diagnosis. Prevention strategies are also discussed. Secondly, we discuss the complexities and challenges encountered when diagnosing and developing treatment strategies for skin cancer...
January 2017: Dermatology and Therapy
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