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"Skin cancer" screening

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https://www.readbyqxmd.com/read/29113361/a-case-control-study-on-association-of-nucleotide-excision-repair-polymorphisms-and-its-interaction-with-environment-factors-with-the-susceptibility-to-non-melanoma-skin-cancer
#1
Yan-Ling Li, Feng Wei, Yu-Ping Li, Li-Hua Zhang, Yan-Zhi Bai
Aims: To investigate the association of several single nucleotide polymorphisms (SNPs) within nucleotide excision repair (NER) gene and additional gene- gene and gene- smoking interaction with non-melanoma skin cancer (NMSC) risk in a Chinese population. Methods: A total of 1322 participants (939 males, 383 females) were selected, including 660 NMSC patients and 662 control participants. Generalized multifactor dimensionality reduction (GMDR) was used to screen the best interaction combination among SNPs and smoking...
October 6, 2017: Oncotarget
https://www.readbyqxmd.com/read/29104226/updates-on-the-management-of-non-melanoma-skin-cancer-nmsc
#2
REVIEW
Artur Fahradyan, Anna C Howell, Erik M Wolfswinkel, Michaela Tsuha, Parthiv Sheth, Alex K Wong
Non-melanoma skin cancers (NMSCs) are the most common malignancy worldwide, of which 99% are basal cell carcinomas (BCCs) and squamous cell carcinomas (SCCs) of skin. NMSCs are generally considered a curable diseases, yet they currently pose an increasing global healthcare problem due to rising incidence. This has led to a shift in emphasis on prevention of NMSCs with development of various skin cancer prevention programs worldwide. This article aims to summarize the most recent changes and advances made in NMSC management with a focus on prevention, screening, diagnosis, and staging...
November 1, 2017: Healthcare (Basel, Switzerland)
https://www.readbyqxmd.com/read/29092508/development-of-a-combined-oct-raman-probe-for-the-prospective-in-vivo-clinical-melanoma-skin-cancer-screening
#3
M Mazurenka, L Behrendt, M Meinhardt-Wollweber, U Morgner, B Roth
A combined optical coherence tomography (OCT)-Raman probe was designed and built into a spectral domain OCT head, and its performance was evaluated and compared to the most common Raman probe setups, based on a fiber bundle and confocal free space optics. Due to the use of the full field of view of an OCT scanning lens, the combined probe has a superior performance within maximum permissible exposure limits, compared to the other two probes. Skin Raman spectra, recorded in vivo, further prove the feasibility of the OCT-Raman probe for the future in vivo clinical applications in skin cancer screening...
October 2017: Review of Scientific Instruments
https://www.readbyqxmd.com/read/29063525/evaluation-of-the-national-skin-cancer-campaign-a-swiss-experience-of-euromelanoma
#4
Sven Lieberherr, S Morteza Seyed Jafari, Simone Cazzaniga, Enrica Bianchi, Bettina Schlagenhauff, Gion Tscharner, Jürg Hafner, Carlo Mainetti, Anne-Karine Lapointe, Robert E Hunger
AIMS OF THE STUDY: Skin cancer is a burden to healthcare and patients worldwide. The incidence of skin cancer has been rising during recent decades and this trend is expected to continue in the future. Numerous risk factors have been identified and prevention strategies developed. The Euromelanoma campaign is a pan-European skin cancer prevention programme, targeted to both primary and secondary prevention of malignant melanoma. The current study aimed to evaluate the results of the Swiss skin cancer screening day 2016...
October 24, 2017: Swiss Medical Weekly
https://www.readbyqxmd.com/read/29061478/impact-of-dermatology-econsults-on-access-to-care-and-skin-cancer-screening-in-underserved-populations-a-model-for-teledermatology-services-in-community-health-centers
#5
Fludiona Naka, Jun Lu, Anthony Porto, Jose Villagra, Zhao Helen Wu, Daren Anderson
BACKGROUND: The clinical outcome of teledermatology with dermoscopy in large-scale primary care networks remains unclear. OBJECTIVE: We evaluate the impact of implementing a teledermatology consultation program with dermoscopy on a statewide scale, focusing on access to care and skin cancer screening for medically underserved populations. METHODS: Descriptive retrospective cohort study of 2385 dermatology referrals from primary care from June 2014 through November 2015...
October 20, 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/29059953/an-embedded-system-for-image-segmentation-and-multimodal-registration-in-noninvasive-skin-cancer-screening
#6
Silvana Diaz, Javier E Soto, Fabian Inostroza, Sebastian E Godoy, Miguel Figueroa
We present a heterogeneous architecture for image registration and multimodal segmentation on an embedded system for noninvasive skin cancer screening. The architecture combines Otsu thresholding and the random walker algorithm to perform image segmentation, and features a hardware implementation of the Harris corner detection algorithm to perform region-of-interest detection and image registration. Running on a Xilinx XC7Z020 reconfigurable system-on-a-chip, our prototype computes the initial segmentation of a 400×400-pixel region of interest in the visible spectrum in 12...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29051341/indoor-tanning-dependence-in-young-adult-women
#7
Darren Mays, Michael B Atkins, Jaeil Ahn, Kenneth P Tercyak
Background: There is mounting evidence that young people can develop a dependence on indoor tanning, but research on factors associated with indoor tanning dependence remains limited.Methods: This cross-sectional study investigated factors associated with indoor tanning dependence in a community sample of 389 non-Hispanic white young adult women ages 18 to 30 who had indoor tanned ≥1 time in the past year. Participants completed measures of indoor tanning dependence, including the modified CAGE and modified Diagnostic and Statistical Manual for Mental Disorders-IV psychiatric screening assessments, indoor tanning behavior and beliefs, and behavioral and psychiatric comorbidity...
November 2017: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/29043858/melanoma-segmentation-based-on-deep-learning
#8
Xiaoqing Zhang
Malignant melanoma is one of the most deadly forms of skin cancer, which is one of the world's fastest-growing cancers. Early diagnosis and treatment is critical. In this study, a neural network structure is utilized to construct a broad and accurate basis for the diagnosis of skin cancer, thereby reducing screening errors. The technique is able to improve the efficacy for identification of normally indistinguishable lesions (such as pigment spots) versus clinically unknown lesions, and to ultimately improve the diagnostic accuracy...
October 18, 2017: Computer Assisted Surgery (Abingdon, England)
https://www.readbyqxmd.com/read/29029040/herbacetin-suppresses-cutaneous-squamous-cell-carcinoma-and-melanoma-cell-growth-by-targeting-akt-and-odc
#9
Dong Joon Kim, Mee-Hyun Lee, KangDong Liu, Do Young Lim, Eunmiri Roh, Hanyong Chen, Sung-Hyun Kim, Jung-Hyun Shim, Myoung Ok Kim, Wenwen Li, Fayang Ma, Mangaladoss Fredimoses, Ann M Bode, Zigang Dong
Herbacetin is a flavonol compound that is found in plants such as flaxseed and ramose scouring rush herb, it possesses a strong antioxidant capacity, and exerts anticancer effects on colon and breast cancer. However, the effect of herbacetin on skin cancer has not been investigated. Herein, we identified herbacetin as a dual V-akt murine thymoma viral oncogene homolog (AKT) and ornithine decarboxylase (ODC) inhibitor, and illustrated its anticancer effects in vitro and in vivo against cutaneous squamous cell carcinoma (SCC) and melanoma cell growth...
October 26, 2017: Carcinogenesis
https://www.readbyqxmd.com/read/28984472/sanger-institute-series-uncovering-the-genetics-of-cancer-an-interview-with-david-adams
#10
David J Adams
Dr David Adams speaks to Editor of Oncology Central, Jade Parker: Based at Wellcome Trust Sanger Institute as a senior group leader, David Adams uses DNA sequencing of patients and genetic screens in human cells and mice to identify cancer genes and genetic interactions. The Adams group studies the mechanisms of cancer development, particularly skin cancer (melanoma) and colorectal cancer. They sequence DNA from families with a high incidence of cancer and also tumors from patients to understand why some people are at greater risk of tumor development and how cancers evolve...
October 6, 2017: Future Oncology
https://www.readbyqxmd.com/read/28971278/a-systematic-review-of-wearable-systems-for-cancer-detection-current-state-and-challenges
#11
Partha Pratim Ray, Dinesh Dash, Debashis De
Rapid growth of sensor and computing platforms have introduced the wearable systems. In recent years, wearable systems have led to new applications across all medical fields. The aim of this review is to present current state-of-the-art approach in the field of wearable system based cancer detection and identify key challenges that resist it from clinical adoption. A total of 472 records were screened and 11 were finally included in this study. Two types of records were studied in this context that includes 45% research articles and 55% manufactured products...
October 2, 2017: Journal of Medical Systems
https://www.readbyqxmd.com/read/28886812/smartphone-based-applications-for-skin-monitoring-and-melanoma-detection
#12
REVIEW
Elizabeth Chao, Chelsea K Meenan, Laura K Ferris
With the advancement of mobile technologies, smartphone applications (apps) have become widely available and gained increasing attention as a novel tool to deliver dermatologic care. This article presents a review of various apps for skin monitoring and melanoma detection and a discussion of current limitations in the field of dermatology. Concerns regarding quality, transparency, and reliability have emerged because there are currently no established quality standards or regulatory oversight of mobile medical apps...
October 2017: Dermatologic Clinics
https://www.readbyqxmd.com/read/28886797/clinical-diagnosis-of-skin-cancer-enhancing-inspection-and-early-recognition
#13
REVIEW
Alex M Glazer, Darrell S Rigel, Richard R Winkelmann, Aaron S Farberg
The annual incidence rate for melanoma and nonmelanoma skin cancer continues to rise and morbidity and deaths from skin cancer are increasing. Despite advances in therapeutics, the factors that most impact prognosis remain early recognition and removal of neoplasms before deep invasion or metastatic disease can occur. There are numerous public health and screening initiatives that have been introduced to help recognize disease earlier and to increase patients' awareness of signs or changes of lesions that may represent skin cancers...
October 2017: Dermatologic Clinics
https://www.readbyqxmd.com/read/28877950/effects-of-complex-interventions-in-skin-cancer-prevention-and-treatment-protocol-for-a-mixed-method-systematic-review-with-qualitative-comparative-analysis
#14
Karolina Beifus, Eckhard Breitbart, Juliane Köberlein-Neu
INTRODUCTION: Occurring from ultraviolet radiation combined with impairing ozone levels, uncritical sun exposure and use of tanning beds an increasing number of people are affected by different types of skin cancer. But preventive interventions like skin cancer screening are still missing the evidence for effectiveness and therefore are criticised. Fundamental for an appropriate course of action is to approach the defined parameters as measures for effectiveness critically. A prerequisite should be the critical application of used parameter that are defined as measures for effectiveness...
September 5, 2017: BMJ Open
https://www.readbyqxmd.com/read/28832980/nationwide-skin-cancer-screening-in-germany-evaluation-of-the-training-program
#15
Markus P Anders, Susanne Fengler, Beate Volkmer, Rüdiger Greinert, Eckhard W Breitbart
BACKGROUND: In July 2008, the German statutory health insurance introduced a nationwide skin cancer screening program. Before the introduction, eligible physicians had to qualify to perform the screening test and counsel their patients on skin cancer screening. To educate physicians, a curriculum and training materials were developed. Since 2015 a revised curriculum and training materials have been used. The purpose of this paper is to provide information about the curriculum and to evaluate the revised training program...
August 18, 2017: International Journal of Dermatology
https://www.readbyqxmd.com/read/28832880/association-of-vitamin-d-receptor-polymorphisms-with-the-risk-of-nonmelanoma-skin-cancer-in-adults
#16
Erin M Burns, Purushotham Guroji, Israr Ahmad, Hana M Nasr, Yingxue Wang, Iman A Tamimi, Elijah Stiefel, Mohammad S Abdelgawwad, Abdullah Shaheen, Anum F Muzaffar, Lisa M Bush, Christina B Hurst, Russell L Griffin, Craig A Elmets, Nabiha Yusuf
Importance: Protective effects of UV-B radiation against nonmelanoma skin cancer (NMSC) are exerted via signaling mechanisms involving the vitamin D receptor (VDR). Recent studies have examined single-nucleotide polymorphisms (SNPs) in the VDR, resulting in contradictory findings as to whether these polymorphisms increase a person's risk for NMSC. Objective: To examine whether the polymorphisms in the VDR gene are associated with the development of NMSC and the demographic characteristics of the participants...
August 23, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28818243/mental-health-problems-and-cancer-risk-factors-among-young-adults
#17
Greta M Massetti, Cheryll C Thomas, Jessica King, Kathleen Ragan, Natasha Buchanan Lunsford
INTRODUCTION: Chronic mental health problems often emerge in young adulthood, when adults begin to develop lifelong health behaviors and access preventive health services. The associations between mental health problems and modifiable cancer risk factors in young adulthood are not well understood. METHODS: In 2016, the authors analyzed 2014 Behavioral Risk Factor Surveillance System data on demographic characteristics, health service access and use, health status, and cancer risk factors (tobacco use, alcohol use, overweight or obesity, physical activity, and sleep) for 90,821 young adults aged 18-39 years with mental health problems (depressive disorder or frequent mental distress) compared to other young adults...
September 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28813744/alkaptonuria-a-case-report-with-diagnostic-challenge
#18
Vasantha L Gali, Amy M Kerkvliet, Jacob M Kusmak, Jana K Elwood
Alkaptonuria is a rare autosomal recessive metabolic disorder caused by deficiency of homogentisic acid (HGA) oxidase, the only enzyme capable of catabolizing HGA. Deficiency of this enzyme leads to excess HGA which deposits in the connective tissue. We present a case of a 64-year-old woman who was referred to the dermatology clinic for a full body mole check and skin cancer screening. Clinically she had blue/gray pigmentation of the external ear and sclera. Also she had a domed papule on the left cheek with punctate gray pigmentation which was biopsied...
August 2017: South Dakota Medicine: the Journal of the South Dakota State Medical Association
https://www.readbyqxmd.com/read/28768305/patient-perceptions-of-primary-care-based-skin-cancer-screening
#19
Amanda R Shaub, Eleanor T Lewis, Susan M Swetter
No abstract text is available yet for this article.
November 1, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28758010/skin-cancer-screening-recommendations-for-data-driven-screening-guidelines-and-a-review-of-the-us-preventive-services-task-force-controversy
#20
REVIEW
Mariah M Johnson, Sancy A Leachman, Lisa G Aspinwall, Lee D Cranmer, Clara Curiel-Lewandrowski, Vernon K Sondak, Clara E Stemwedel, Susan M Swetter, John Vetto, Tawnya Bowles, Robert P Dellavalle, Larisa J Geskin, Douglas Grossman, Kenneth F Grossmann, Jason E Hawkes, Joanne M Jeter, Caroline C Kim, John M Kirkwood, Aaron R Mangold, Frank Meyskens, Michael E Ming, Kelly C Nelson, Michael Piepkorn, Brian P Pollack, June K Robinson, Arthur J Sober, Shannon Trotter, Suraj S Venna, Sanjiv Agarwala, Rhoda Alani, Bruce Averbook, Anna Bar, Mirna Becevic, Neil Box, William E Carson, Pamela B Cassidy, Suephy C Chen, Emily Y Chu, Darrel L Ellis, Laura K Ferris, David E Fisher, Kari Kendra, David H Lawson, Philip D Leming, Kim A Margolin, Svetomir Markovic, Mary C Martini, Debbie Miller, Debjani Sahni, William H Sharfman, Jennifer Stein, Alexander J Stratigos, Ahmad Tarhini, Matthew H Taylor, Oliver J Wisco, Michael K Wong
Melanoma is usually apparent on the skin and readily detected by trained medical providers using a routine total body skin examination, yet this malignancy is responsible for the majority of skin cancer-related deaths. Currently, there is no national consensus on skin cancer screening in the USA, but dermatologists and primary care providers are routinely confronted with making the decision about when to recommend total body skin examinations and at what interval. The objectives of this paper are: to propose rational, risk-based, data-driven guidelines commensurate with the US Preventive Services Task Force screening guidelines for other disorders; to compare our proposed guidelines to recommendations made by other national and international organizations; and to review the US Preventive Services Task Force's 2016 Draft Recommendation Statement on skin cancer screening...
March 2017: Melanoma Management
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