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https://www.readbyqxmd.com/read/27911487/external-inspection-of-compliance-with-standards-for-improved-healthcare-outcomes
#1
REVIEW
Gerd Flodgren, Daniela C Gonçalves-Bradley, Marie-Pascale Pomey
BACKGROUND: Inspection systems are used in healthcare to promote quality improvements (i.e. to achieve changes in organisational structures or processes, healthcare provider behaviour and patient outcomes). These systems are based on the assumption that externally promoted adherence to evidence-based standards (through inspection/assessment) will result in higher quality of healthcare. However, the benefits of external inspection in terms of organisational-, provider- and patient-level outcomes are not clear...
December 2, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27911404/using-capillary-electrophoresis-to-quantify-organic-acids-from-plant-tissue-a-test-case-examining-coffea-arabica-seeds
#2
Michael Joe Vaughan, Ann Chanon, Joshua J Blakeslee
Carboxylic acids are organic acids containing one or more terminal carboxyl (COOH) functional groups. Short chain carboxylic acids (SCCAs; carboxylic acids containing three to six carbons), such as malate and citrate, are critical to the proper functioning of many biological systems, where they function in cellular respiration and can serve as indicators of cell health. In foods, organic acid content can have significant impact on taste, with increased SCCA levels resulting in a sour or "acid" taste. Because of this, methods for the rapid analysis of organic acid levels are of particular interest to the food and beverage industries...
November 12, 2016: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/27911282/role-of-rehabilitation-in-hurler-s-syndrome
#3
Sudhir Ramkishore Mishra, Mona Shastri, Jaishree Ramesh
Hurler syndrome is an inherited autosomal recessive disorder of lysosomal accumulation of un-degraded glucosaminoglycan secondary to deficiency of a-L-Iduronidase enzyme. It is most severe form of Mucopolysaccharidosis with incidence of 1:100 000. It has multisystemic involvement leading to multiple deformity, disability and death within 10th years of life. A 2 year old boy presented with umbilical hernia, gross developmental delay and a progressive spinal deformity. On detailed clinical, radiological and laboratory investigation he was diagnosed as Hurler's syndrome...
November 25, 2016: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/27911228/erratum-screening-via-ct-angiogram-after-traumatic-cervical-spine-fractures-narrowing-imaging-to-improve-cost-effectiveness-experience-of-a-level-i-trauma-center
#4
Gabriel A Smith
No abstract text is available yet for this article.
December 2, 2016: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/27911141/mindfulness-based-intervention-for-perinatal-grief-in-rural-india-improved-mental-health-at-12%C3%A2-months-follow-up
#5
Lisa R Roberts, Susanne B Montgomery
Stillbirth is a significant global health problem that frequently results in perinatal grief with compound negative psychosocial impact. In low-resource settings with exceedingly high stillbirth rates, such as rural Chhattisgarh, India, it is vital to utilize low-cost, effective interventions. Mindfulness-based stress reduction is an evidence-based intervention utilized for a broad range of physical and mental health problems, and is adaptable to specific populations. The objective of this study was to explore the sustained effectiveness of a shortened, culturally adapted mindfulness-based intervention (MBI) designed to address complex grief after stillbirth...
December 2, 2016: Issues in Mental Health Nursing
https://www.readbyqxmd.com/read/27911073/reducing-risky-alcohol-use-what-health-care-systems-can-do
#6
Amity E Quinn, Mary Brolin, Maureen T Stewart, Brooke Evans, Constance Horgan
Risky, non-dependent alcohol use is prevalent in the United States, affecting 25% of adults (Centers for Disease Control and Prevention, 2014b). Massachusetts has higher rates of alcohol use and binge drinking than most states (Substance Abuse and Mental Health Services Administration, 2015). Serious physical, social, and economic consequences result. Excessive alcohol use contributes to cancer, cardiovascular disease, sleep disorders, birth defects, motor vehicle injuries, and suicide, and it complicates management of chronic illnesses (Green, McKnight-Eily, Tan, Mejia, & Denny, 2016; Laramee et al...
April 27, 2016: Issue Brief
https://www.readbyqxmd.com/read/27910852/kaleidoscopic-imaging-patterns-of-complex-structures-fabricated-by-laser-induced-deformation
#7
Haoran Zhang, Fengyou Yang, Jianjie Dong, Lena Du, Chuang Wang, Jianming Zhang, Chuan Fei Guo, Qian Liu
Complex surface structures have stimulated a great deal of interests due to many potential applications in surface devices. However, in the fabrication of complex surface micro-/nanostructures, there are always great challenges in precise design, or good controllability, or low cost, or high throughput. Here, we present a route for the accurate design and highly controllable fabrication of surface quasi-three-dimensional (quasi-3D) structures based on a thermal deformation of simple two-dimensional laser-induced patterns...
December 2, 2016: Nature Communications
https://www.readbyqxmd.com/read/27910721/care-delivery-considerations-for-widespread-and-equitable-implementation-of-inherited-cancer-predisposition-testing
#8
Deborah Cragun, Anita Y Kinney, Tuya Pal
DNA sequencing advances through next-generation sequencing (NGS) and several practice changing events, have led to shifting paradigms for inherited cancer predisposition testing. These changes necessitated a means by which to maximize health benefits without unnecessarily inflating healthcare costs and exacerbating health disparities. Areas covered: NGS-based tests encompass multi-gene panel tests, whole exome sequencing, and whole genome sequencing, all of which test for multiple genes simultaneously, compared to prior sequencing practices through which testing was performed sequentially for one or two genes...
December 2, 2016: Expert Review of Molecular Diagnostics
https://www.readbyqxmd.com/read/27910659/the-multi-spectral-line-polarization-mse-system-on-alcator-c-mod
#9
R T Mumgaard, S D Scott, M Khoury
A multi-spectral line-polarization motional Stark effect (MSE-MSLP) diagnostic has been developed for the Alcator C-Mod tokamak wherein the Stokes vector is measured in multiple wavelength bands simultaneously on the same sightline to enable better polarized background subtraction. A ten-sightline, four wavelength MSE-MSLP detector system was designed, constructed, and qualified. This system consists of a high-throughput polychromator for each sightline designed to provide large étendue and precise spectral filtering in a cost-effective manner...
November 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27910362/a-novel-cost-effective-multi-point-thomson-scattering-system-on-the-pegasus-toroidal-experiment-invited
#10
D J Schlossberg, G M Bodner, M W Bongard, R J Fonck, J A Reusch, C Rodriguez Sanchez
A novel, cost-effective, multi-point Thomson scattering system has been designed, implemented, and operated on the Pegasus Toroidal Experiment. Leveraging advances in Nd:YAG lasers, high-efficiency volume phase holographic transmission gratings, and increased quantum-efficiency Generation 3 image-intensified charge coupled device (ICCD) cameras, the system provides Thomson spectra at eight spatial locations for a single grating/camera pair. The on-board digitization of the ICCD camera enables easy modular expansion, evidenced by recent extension from 4 to 12 plasma/background spatial location pairs...
November 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27910116/the-cost-effectiveness-of-testing-for-ns5a-resistance-associated-polymorphisms-at-baseline-in-genotype-1a-infected-treatment-na%C3%A3-ve-and-treatment-experienced-subjects-treated-with-all-oral-elbasvir-grazoprevir-regimens-in-the-united-states
#11
E H Elbasha, M N Robertson, C Nwankwo
BACKGROUND: The presence of baseline NS5A resistance-associated variants (RAVs) impacted treatment response in HCV genotype 1a (GT1a)-infected patients treated with elbasvir/grazoprevir (EBR/GZR) for 12 weeks, but not patients treated with EBR/GZR and ribavirin (RBV) for 16 weeks. AIM: We assessed the cost-effectiveness of baseline testing for NS5A RAVs in EBR/GZR-treated patients compared without testing and with current treatments for GT1a patients. METHODS: We simulated the course of treatment with EBR/GZR, ledipasvir/sofosbuvir (LDV/SOF) and ombitasvir/paritaprevir/ritonavir+dasabuvir (3D) with or without RBV and natural history of disease of GT1a patients...
December 1, 2016: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/27910088/the-efficacy-of-greater-occipital-nerve-blockade-in-chronic-migraine-a-placebo-controlled-study
#12
H L Gul, A O Ozon, O Karadas, G Koc, L E Inan
OBJECTIVE: GON blockade with local anesthetics is an effective treatment for a group of headaches, such as cervicogenic headache, cluster headache, occipital neuralgia, migraine. Our aim was to evaluate the efficacy of greater occipital nerve (GON) blockade in patients with chronic migraine (CM) by using a control group. MATERIALS AND METHODS: We included 44 CM patients and randomly divide the patients into two groups, as group A (bupivacaine) and group B (placebo) to our study...
December 2, 2016: Acta Neurologica Scandinavica
https://www.readbyqxmd.com/read/27909996/modelling-the-cost-effectiveness-of-human-milk-and-breastfeeding-in-preterm-infants-in-the-united-kingdom
#13
James Mahon, Lindsay Claxton, Hannah Wood
OBJECTIVES: To estimate the cost savings and health benefits in the UK NHS that could be achieved if human milk usage in the NICU was increased. METHODS: A systematic review established the disease areas with the strong sources of evidence of the short, medium and long-term benefits of human milk for preterm infants as opposed to the use of formula milk. The analysis assessed the economic impact of reducing rates of necrotising enterocolitis, sepsis, sudden infant death syndrome, leukaemia, otitis media, obesity and neurodevelopmental impairment...
December 2016: Health Economics Review
https://www.readbyqxmd.com/read/27909928/erratum-to-cost-effective-enhanced-iron-bioavailability-in-rice-grain-grown-on-calcareous-soil-by-sulfur-mediation-and-its-effect-on-heavy-metals-mineralization
#14
Pia Muhammad Adnan Ramzani, Muhammad Khalid, Shazia Anjum, Waqas-Ud-Din Khan, Shafaqat Ali, Fakhir Hannan, Muhammad Iqbal
No abstract text is available yet for this article.
December 2, 2016: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/27909924/tailor-made-biocatalysts-based-on-scarcely-studied-acidic-horseradish-peroxidase-for-biodegradation-of-reactive-dyes
#15
Barbara S Janović, Milica Lj Mićić Vićovac, Zoran M Vujčić, Miroslava T Vujčić
Peroxidases (EC 1.11.1.7) have enormous biotechnological applications. Usage of more abundant, basic isoforms of peroxidases in diagnostic kits and/or in immunochemistry has led to under exploitation and disregard of horseradish peroxidase (HRP) acidic isoforms. Therefore, acidic horseradish peroxidase (HRP-A) isoenzyme was used for the preparation of a biocatalyst with improved ability in dye decolorization. Ten biocatalysts were prepared by covalent binding of enzyme to chitosan and alginate, adsorption followed by cross-linking on inorganic support (aluminum oxide), and encapsulation in spherical calcium alginate beads via polyethylene glycol...
December 1, 2016: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/27909845/a-fluorescence-sensor-for-lead-ii-ions-determination-based-on-label-free-gold-nanoparticles-gnps-dnazyme-using-time-gated-mode-in-aqueous-solution
#16
Xiao-Yu Wang, Cheng-Gang Niu, Li-Juan Guo, Liu-Yin Hu, Sheng-Quan Wu, Guang-Ming Zeng, Fei Li
This paper describes a label-free 17E DNAzyme-based time-gated fluorescence sensor for Pb(2+) detection by unmodified gold nanoparticles (GNPs) and a terbium ternary complex. The fluorophore that used in this paper is a terbium ternary complex. Its signal can be measured in a time-gated manner which could eliminate most of the unspecific fluorescent background. It is well known that unfolded single-stranded DNA (ssDNA) could be adsorbed on GNPs while double-stranded DNA could not. The cleavage of the substrate by the 17E DNAzyme in the presence of Pb(2+) causes the release of ssDNA from the 17E-17S duplex to be absorbed onto GNPs, preventing the aggregation of GNPs and then leading to a fluorescence decrease of terbium ternary complex...
December 1, 2016: Journal of Fluorescence
https://www.readbyqxmd.com/read/27909844/design-and-fabrication-a-gold-nanoparticle-dna-based-nanobiosensor-for-detection-of-microrna-involved-in-alzheimer-s-disease
#17
Shokoufeh Delkhahi, Mahdi Rahaie, Fereshteh Rahimi
MicroRNAs are small RNAs which regulate gene expression by translational repression or degradation of messenger RNAs. Regards to important role of these biomolecules in human disease progress, to produce sensitive, simple and cost-effective assays for microRNAs are in urgent demand. miR-137 in Alzheimer's patients has demonstrated its potential as non-invasive biomarkers in blood for Alzheimer's disease diagnosis and prognosis. This paper describes a novel, sensitive and specific microRNA assay based on Colorimetric detection of gold nanoparticles and hybridization chain reaction amplification (HCR)...
December 1, 2016: Journal of Fluorescence
https://www.readbyqxmd.com/read/27909819/cost-effects-of-preterm-birth-a-comparison-of-health-care-costs-associated-with-early-preterm-late-preterm-and-full-term-birth-in-the-first-3%C3%A2-years-after-birth
#18
Josephine Jacob, Moritz Lehne, Andrea Mischker, Normen Klinger, Claudia Zickermann, Jochen Walker
Preterm birth is one of the main causes for infant morbidity and mortality. Apart from negative health outcomes, preterm birth also produces significant health care expenditures. This study evaluates the costs associated with preterm birth in different health sectors during the first 3 years of infants' lives. In a retrospective observational study based on claims data from a German statutory health insurance company, average costs for medication, hospital treatment, ambulatory treatment, and non-medical remedies during the first 3 years after birth were analyzed for early preterm, late preterm, and full-term births...
December 1, 2016: European Journal of Health Economics: HEPAC: Health Economics in Prevention and Care
https://www.readbyqxmd.com/read/27909673/how-to-build-your-simple-and-cost-effective-arthroscopic-skills-simulator
#19
Georgios Arealis, James Holton, Joana Bento Rodrigues, Maria Sagkrioti, Martyn Snow, Mark Hamlet, Ofer Levy
Acquisition of arthroscopic skills is not always easy and can be time-consuming. Simulation in arthroscopy improves surgical skills and can bridge the gap between reduced surgical exposure and training time and the need to reach a required level of competency. We propose a method to create a simple and cost-effective arthroscopic skills simulator using readily available materials and a low-cost Web camera available from online shops. This arthroscopic simulation device can be used to improve skills of all levels of trainees at home, in a bioskills laboratory, or in the theater...
October 2016: Arthroscopy Techniques
https://www.readbyqxmd.com/read/27909633/the-hidden-curriculum-exposing-the-unintended-lessons-of-medical-education
#20
Laura Hopkins, Lana Saciragic, Joanna Kim, Glenn Posner
INTRODUCTION:  The hidden curriculum is a set of ethical, moral, and value-based teachings communicated to doctors-in-training, providing a basis for their future interactions with patients, peers, and colleagues. The aim of our study is to introduce the concept of the hidden curriculum to a cohort of third-year medical students and to subsequently evaluate their understanding. In particular, we sought to measure and benchmark the degree of hidden curriculum recognition within a Canadian medical education context...
October 25, 2016: Curēus
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