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https://www.readbyqxmd.com/read/29232277/scaling-up-hiv-self-testing-in-sub-saharan-africa-a-review-of-technology-policy-and-evidence
#1
Pitchaya P Indravudh, Augustine T Choko, Elizabeth L Corbett
PURPOSE OF REVIEW: HIV self-testing (HIVST) can provide complementary coverage to existing HIV testing services and improve knowledge of status among HIV-infected individuals. This review summarizes the current technology, policy and evidence landscape in sub-Saharan Africa and priorities within a rapidly evolving field. RECENT FINDINGS: HIVST is moving towards scaled implementation, with the release of WHO guidelines, WHO prequalification of the first HIVST product, price reductions of HIVST products and a growing product pipeline...
December 9, 2017: Current Opinion in Infectious Diseases
https://www.readbyqxmd.com/read/29232257/economics-of-gynecologic-morcellation
#2
Pietro Bortoletto, Jaclyn Friedman, Magdy P Milad
PURPOSE OF REVIEW: As the Food and Drug Administration raised concern over the power morcellator in 2014, the field has seen significant change, with patients and physicians questioning which procedure is safest and most cost-effective. The economic impact of these decisions is poorly understood. RECENT FINDINGS: Multiple new technologies have been developed to allow surgeons to continue to afford patients the many benefits of minimally invasive surgery while minimizing the risks of power morcellation...
December 11, 2017: Current Opinion in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29232212/cost-of-major-complications-after-liver-resection-in-the-united-states-are-high-volume-centers-cost-effective
#3
Jay J Idrees, Fabian M Johnston, Joseph K Canner, Mary Dillhoff, Carl Schmidt, Elliott R Haut, Timothy M Pawlik
OBJECTIVE: The aim of the study was to estimate the cost of major complications after liver resection and determine whether high-volume (HV) centers are cost-effective. METHODS: From 2002 to 2011, 96,107 cases of liver resection performed in the United States were identified using Nationwide Inpatient Sample. Hospitals were categorized as HV (150+ cases/yr), medium-volume (51-149 cases/yr), and low-volume (LV) (1-50 cases/yr) centers. Multivariable regression analysis identified predictors of cost...
December 11, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/29232047/antibiotic-prophylaxis-in-ureteroscopic-lithotripsy-a%C3%A2-systematic-review-and-meta-analysis-of-comparative-studies
#4
Tuo Deng, Bing Liu, Xiaolu Duan, Chao Cai, Zhijian Zhao, Wei Zhu, Junhong Fan, Wenqi Wu, Guohua Zeng
OBJECTIVE: To explore the efficacy and detailed strategies of antibiotic prophylaxis in ureteroscopic lithotripsy (URL) through a systematic review and meta-analysis. MATERIALS AND METHODS: A systematic literature search using Pubmed, Embase, Medline, Cochrane Library, CBM, CNKI and VIP databases was performed to obtain comparative studies on the efficacy of different antibiotic prophylaxis strategies in URL for preventing postoperative infections. The last search was conducted on June 25, 2017...
December 12, 2017: BJU International
https://www.readbyqxmd.com/read/29231973/comparative-effectiveness-of-prostate-cancer-screening-between-the-ages-of-55-and-69-years-followed-by-active-surveillance
#5
Tiago M de Carvalho, Eveline A M Heijnsdijk, Harry J de Koning
BACKGROUND: Because of the recent grade C draft recommendation by the US Preventive Services Task Force (USPSTF) for prostate cancer screening between the ages of 55 and 69 years, there is a need to determine whether this could be cost-effective in a US population setting. METHODS: This study used a microsimulation model of screening and active surveillance (AS), based on data from the European Randomized Study of Screening for Prostate Cancer and the Surveillance, Epidemiology, and End Results Program, for the natural history of prostate cancer and Johns Hopkins AS cohort data to inform the probabilities of referral to treatment during AS...
December 12, 2017: Cancer
https://www.readbyqxmd.com/read/29231885/development-of-a-sequential-injection-analysis-system-for-the-determination-of-saccharin
#6
Budi Wibowotomo, Jong-Bang Eun, Jong Il Rhee
Saccharin is a powerfully sweet nonnutritive sweetener that has been approved for food-processing applications within the range of 100-1200 mg/kg. A simple, rapid, and cost-effective sequential injection analysis (SIA) technique was developed to determine the saccharin level. This method is based on the reaction of saccharin with p-chloranil in an ethanol medium with a hydrogen peroxide (H₂O₂) acceleration, and the resultant violet-red compound was detected using a UV-Vis spectrophotometer at λmax = 420 nm...
December 12, 2017: Sensors
https://www.readbyqxmd.com/read/29231778/case-study-of-an-epidemiological-approach-dissecting-historical-soybean-sclerotinia-stem-rot-observations-and-identifying-environmental-predictors-of-epidemics-and-yield-loss
#7
Mamadou Lamine Fall, John F Boyse, Dechun Wang, Jamie F Willbur, Damon Smith, Martin I Chilvers
Sclerotinia sclerotiorum is a significant threat to soybean production worldwide. In this study, an epidemiological approach was used to examine 11 years of historical data from a soybean management performance trial in order to advance our understanding of Sclerotinia stem rot (SSR) development and to identify environmental predictors of SSR epidemics and associated yield losses. Recursive partitioning analysis suggested that average air temperature and total precipitation in July were the most significant variables associated with disease severity...
December 12, 2017: Phytopathology
https://www.readbyqxmd.com/read/29231180/realization-of-synaptic-learning-and-memory-functions-in-y2o3-based-memristive-device-fabricated-by-dual-ion-beam-sputtering
#8
Mangal Das, Amitesh Kumar, Rohit Singh, Myo Than Htay, Shaibal Mukherjee
Single synaptic device with inherent learning and memory functions is demonstrated based on a forming-free amorphous Y2O3 (yttria) memristor fabricated by dual ion beam sputtering system. Synaptic functions such as nonlinear transmission characteristics, long-term plasticity, short-term plasticity and "learning behavior" are achieved using a single synaptic device based on cost-effective metal-insulator- semiconductor (MIS) structure. A "learning behavior" function is demonstrated, for the first time in the literature, for yttria based memristor, which bears resemblance to certain memory functions of biological systems...
December 12, 2017: Nanotechnology
https://www.readbyqxmd.com/read/29231159/facet-joint-injections-for-non-specific-low-back-pain-a-feasibility-rct
#9
Saowarat Snidvongs, Rod S Taylor, Alia Ahmad, Simon Thomson, Manohar Sharma, Angela Farr, Deborah Fitzsimmons, Stephanie Poulton, Vivek Mehta, Richard Langford
BACKGROUND: Pain of lumbar facet-joint origin is a common cause of low back pain in adults and may lead to chronic pain and disability, with associated health and socioeconomic implications. The socioeconomic burden includes an inability to return to work resulting in loss of productivity in addition to direct and indirect health-care utilisation costs. Lumbar facet-joints are paired synovial joints between the superior and inferior articular processes of consecutive lumbar vertebrae and between the fifth lumbar vertebra and the sacrum...
December 2017: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/29231153/antibiotic-susceptibility-pattern-of-neisseria-gonorrhoeae-strains-isolated-from-five-cities-in-india-during-2013-2016
#10
Sangeeta V Kulkarni, Manju Bala, Syeeda A Muqeeth, G Sasikala, Amit P Nirmalkar, R Thorat, H Kambli, Jyoti Sawant, Arun Risbud, Raman R Gangakhedkar, Sheela V Godbole
PURPOSE: Emergence of multidrug resistance in Neisseria gonorrhoeae, an STI of public health significance is the biggest challenge to gonorrhoea control. Monitoring for antimicrobial resistance is essential for the early detection of emergent drug resistance patterns. METHODOLOGY: One hundred and twenty four N. gonorrhoeae strains were isolated between September 2013-August 2016 [82-New Delhi, 3-Pune, 3-Mumbai, 20-Secunderabad and 16-Hyderabad] to determine antimicrobial susceptibility and to compare the CLSI disc diffusion method with Etest for these strains...
December 12, 2017: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/29231134/plant-made-antibodies-properties-and-therapeutic-applications
#11
Tatianamsu Ru V Komarova, Ekaterina V Sheshukova, Yuri L Dorokhov
A cost-effective plant platform for therapeutic monoclonal antibody production is both flexible and scalable. In addition, plant-made antibodies (PMAbs) could be advantageous compared to those produced in animal cells due to the absence of a risk of contamination from nucleic acids or proteins of animal origin. In this review, the various platforms of PMAbs production are described, and the widely used transient expression system based on Agrobacterium-mediated delivery of genetic material into plant cells is discussed in detail...
December 11, 2017: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/29231047/cost-effectiveness-analysis-of-treatments-involving-radioembolization-in-intermediate-stage-hepatocellular-carcinoma
#12
Carla Rognoni, Oriana Ciani, Silvia Sommariva, Rosanna Tarricone
AIM: We evaluated two treatment sequences, transarterial radioembolization followed by transarterial chemoembolization and possibly sorafenib (=TTS) versus transarterial radioembolization followed by sorafenib alone (=TS), to identify the most cost-effective pathway to treat intermediate-stage hepatocellular carcinoma from the Italian healthcare system perspective. MATERIALS & METHODS: A Markov model was developed to project costs and health outcomes for TTS and TS over a lifetime horizon...
December 12, 2017: Journal of Comparative Effectiveness Research
https://www.readbyqxmd.com/read/29230905/muscle-control-and-non-specific-chronic-low-back-pain
#13
REVIEW
Marc Russo, Kristiaan Deckers, Sam Eldabe, Kyle Kiesel, Chris Gilligan, John Vieceli, Peter Crosby
OBJECTIVES: Chronic low back pain (CLBP) is the most prevalent of the painful musculoskeletal conditions. CLBP is a heterogeneous condition with many causes and diagnoses, but there are few established therapies with strong evidence of effectiveness (or cost effectiveness). CLBP for which it is not possible to identify any specific cause is often referred to as non-specific chronic LBP (NSCLBP). One type of NSCLBP is continuing and recurrent primarily nociceptive CLBP due to vertebral joint overload subsequent to functional instability of the lumbar spine...
December 12, 2017: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/29230720/erratum-to-robust-cost-effective-profiling-of-rna-binding-protein-targets-with-single-end-enhanced-crosslinking-and-immunoprecipitation-seclip
#14
Eric L Van Nostrand, Thai B Nguyen, Chelsea Gelboin-Burkhart, Ruth Wang, Steven M Blue, Gabriel A Pratt, Ashley L Louie, Gene W Yeo
No abstract text is available yet for this article.
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29230687/effectiveness-of-online-cancer-education-for-nurses-and-allied-health-professionals-a-systematic-review-using-kirkpatrick-evaluation-framework
#15
Karen Campbell, Vanessa Taylor, Sheila Douglas
Embedding online learning within higher education can provide engaging, cost-effective, interactive and flexible education. By evaluating the impact, outcomes and pedagogical influence of online cancer and education, future curricula can be shaped and delivered by higher education providers to better meet learner, health care provider and educational commissioners' requirements for enhanced patient care and service delivery needs. Using the Kirkpatrick's four-level model of educational evaluation, a systematic review of the effectiveness of online cancer education for nurses and allied health professionals was conducted...
December 12, 2017: Journal of Cancer Education: the Official Journal of the American Association for Cancer Education
https://www.readbyqxmd.com/read/29230637/conception-and-validation-of-a-protocol-for-reuse-of-non-irrigated-electrophysiology-catheters-in-a-brazilian-teaching-hospital
#16
Mirtes Loeschner Leichsenring, Eliane Molina Psaltikidis, Márcio Jansen de Oliveira Figueiredo, Maria Luiza Moretti, Plínio Trabasso
PURPOSE: Since the Brazilian current legislation permits the reuse of single-use devices under a validated processing protocol, the main purpose of our study was to develop and validate a method for reusing non-irrigated electrophysiology catheter (EC). METHODS: Manual and mechanical processing by ultrasonic washer was associated with the use of enzymatic solution and hydrogen peroxide with a final rinse with filtered water. Validation of the cleaning process, as well as catheter integrity, was done by observing the ECs in stereoscopic microscope at ×60 magnification, followed by HemoCheck-S® (HCS) test to monitor the presence of residual blood on their surfaces...
December 11, 2017: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
https://www.readbyqxmd.com/read/29230543/the-contents-and-distributions-of-cadmium-mercury-and-lead-in-usnea-antarctica-lichens-from-solorina-valley-james-ross-island-antarctica
#17
Ondřej Zvěřina, Pavel Coufalík, Miloš Barták, Michal Petrov, Josef Komárek
Lichens are efficient and cost-effective biomonitors of the environment. Their geographic distribution together with their slow growth rate enable investigation of the deposition patterns of various elements and substances. In this research, levels of cadmium, lead, and mercury in Usnea antarctica lichens in the area of James Ross Island, Antarctica, were investigated. The lichens were microwave-digested, and the metals were determined by means of atomic absorption spectrometry with graphite furnace and a direct mercury analyzer...
December 11, 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/29230474/cost-effectiveness-of-individualized-management-of-diabetes-among-u-s-adults
#18
(no author information available yet)
No abstract text is available yet for this article.
December 12, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/29230472/individualized-glycemic-control-for-u-s-adults-with-type-2-diabetes-a-cost-effectiveness-analysis
#19
Neda Laiteerapong, Jennifer M Cooper, M Reza Skandari, Philip M Clarke, Aaron N Winn, Rochelle N Naylor, Elbert S Huang
Background: Intensive glycemic control in type 2 diabetes (glycated hemoglobin [HbA1c] level <7%) is an established, cost-effective standard of care. However, guidelines recommend individualizing goals on the basis of age, comorbidity, diabetes duration, and complications. Objective: To estimate the cost-effectiveness of individualized control versus uniform intensive control (HbA1c level <7%) for the U.S. population with type 2 diabetes. Design: Patient-level Monte Carlo-based Markov model...
December 12, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/29230429/cost-effectiveness-analysis-of-probiotic-use-to-prevent-clostridium-difficile-infection-in-hospitalized-adults-receiving-antibiotics
#20
Nicole T Shen, Jared A Leff, Yecheskel Schneider, Carl V Crawford, Anna Maw, Brian Bosworth, Matthew S Simon
Background: Systematic reviews with meta-analyses and meta-regression suggest that timely probiotic use can prevent Clostridium difficile infection (CDI) in hospitalized adults receiving antibiotics, but the cost effectiveness is unknown. We sought to evaluate the cost effectiveness of probiotic use for prevention of CDI versus no probiotic use in the United States. Methods: We programmed a decision analytic model using published literature and national databases with a 1-year time horizon...
2017: Open Forum Infectious Diseases
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