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https://www.readbyqxmd.com/read/28226816/neural-representation-of-different-mandarin-tones-in-the-inferior-colliculus-of-the-guinea-pig
#1
Fei Peng, Nan Xia, Xing Wang, Xiao L Zheng, Yi Zhou, Xing Y Fan, Wen S Hou, Fei Peng, Nan Xia, Xing Wang, Xiao L Zheng, Yi Zhou, Xing Y Fan, Wen S Hou, Xing Y Fan, Nan Xia, Wen S Hou, Xing Wang, Yi Zhou, Fei Peng, Xiao L Zheng
Mandarin speech has four different tones and the coding mechanism underlying tone identification still remain unclear. Here in the inferior colliculus (IC) of anesthetized guinea pigs, we recorded single neuron activities to one word with four tones using tungsten electrode. Peri-stimulus time histograms (PSTHs) and inter-spike-interval (ISI) were used to evaluate the neural response. The results showed that PSTHs grouped into frequency band reflected the spectrotemporal patterns of different tones; average population PSTHs matched envelops of different tones; and the peaks of histogram of ISIs in three time segments exhibited a displacement which reflected the profile of fundamental frequency (F0)...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28224173/speech-audiometric-assessment-of-informational-masking
#2
S Rählmann, H Meister
BACKGROUND: In communication situations with multiple speakers, speech recognition is adversely affected by energetic masking (EM) and informational masking (IM). IM characterizes masking effects caused by irrelevant information from competing speakers. This work investigates an approach to assess IM based on the Oldenburg Sentence Test (OLSA). Furthermore, the influence of interaural time differences (ITD) and aging effects on IM are considered. MATERIALS AND METHODS: IM was measured by superimposing two sentences from the OLSA...
February 21, 2017: HNO
https://www.readbyqxmd.com/read/28223951/speechreading-in-deaf-adults-with-cochlear-implants-evidence-for-perceptual-compensation
#3
Hannah Pimperton, Amelia Ralph-Lewis, Mairéad MacSweeney
Previous research has provided evidence for a speechreading advantage in congenitally deaf adults compared to hearing adults. A 'perceptual compensation' account of this finding proposes that prolonged early onset deafness leads to a greater reliance on visual, as opposed to auditory, information when perceiving speech which in turn results in superior visual speech perception skills in deaf adults. In the current study we tested whether previous demonstrations of a speechreading advantage for profoundly congenitally deaf adults with hearing aids, or no amplificiation, were also apparent in adults with the same deafness profile but who have experienced greater access to the auditory elements of speech via a cochlear implant (CI)...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28220929/increasing-the-efficiency-on-producing-radiology-reports-for-breast-cancer-diagnosis-by-means-of-structured-reports-a-comparative-study
#4
J Damian Segrelles, Rosana Medina, Ignacio Blanquer, Luis Martí-Bonmatí
BACKGROUND: Radiology reports are commonly written on free-text using voice recognition devices. Structured reports (SR) have a high potential but they are usually considered more difficult to fill-in so their adoption in clinical practice leads to a lower efficiency. However, some studies have demonstrated that in some cases, producing SRs may require shorter time than plain-text ones. This work focuses on the definition and demonstration of a methodology to evaluate the productivity of software tools for producing radiology reports...
February 21, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/28212718/a-speech-and-psychological-profile-of-treatment-seeking-adolescents-who-stutter
#5
Lisa Iverach, Robyn Lowe, Mark Jones, Susan O'Brian, Ross G Menzies, Ann Packman, Mark Onslow
PURPOSE: The purpose of this study was to evaluate the relationship between stuttering severity, psychological functioning, and overall impact of stuttering, in a large sample of adolescents who stutter. METHOD: Participants were 102 adolescents (11-17 years) seeking speech treatment for stuttering, including 86 boys and 16 girls, classified into younger (11-14 years, n=57) and older (15-17 years, n=45) adolescents. Linear regression models were used to evaluate the relationship between speech and psychological variables and overall impact of stuttering...
March 2017: Journal of Fluency Disorders
https://www.readbyqxmd.com/read/28196001/efficacy-of-bone-anchored-hearing-aids-in-single-sided-deafness-a-systematic-review
#6
Gaeun Kim, Hyun Mi Ju, Sun Hee Lee, Hee-Soon Kim, Jeong A Kwon, Young Joon Seo
OBJECTIVES: Bone-anchored hearing aids (BAHAs) have been known to partially restore some of the functions lost in subjects with single-sided deafness (SSD). Our aims in this systemic review were to analyze the present capabilities of BAHAs in the context of SSD, and to evaluate the efficacy of BAHAs in improving speech recognition in noisy conditions, sound localization, and subjective outcomes. DESIGN: A systematic search was undertaken until August 2015 by two independent reviewers, with disagreements resolved by consensus...
February 10, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28180184/a-gain-of-function-mutation-in-the-grik2-gene-causes-neurodevelopmental-deficits
#7
Yomayra F Guzmán, Keri Ramsey, Jacob R Stolz, David W Craig, Mathew J Huentelman, Vinodh Narayanan, Geoffrey T Swanson
OBJECTIVE: To identify inherited or de novo mutations associated with a suite of neurodevelopmental abnormalities in a 10-year-old patient displaying ataxia, motor and speech delay, and intellectual disability. METHODS: We performed whole-exome sequencing of the proband and her parents. A pathogenic gene variant was identified as damaging based on sequence conservation, gene function, and association with disorders having similar phenotypic profiles. Functional characterization of the mutated protein was performed in vitro using a heterologous expression system...
February 2017: Neurology. Genetics
https://www.readbyqxmd.com/read/28155306/an-audiological-profile-of-patients-infected-with-multi-drug-resistant-tuberculosis-at-a-district-hospital-in-kwazulu-natal
#8
Delicia Appana, Lavanithum Joseph, Jessica Paken
BACKGROUND: The increased incidence of multi-drug-resistant tuberculosis (MDR-TB) and the consequent use of aminoglycosides with their ototoxic potential necessitate a better understanding of the audiological pattern of infected patients. OBJECTIVE: To describe the occurrence and nature of hearing loss in patients with MDR-TB receiving aminoglycosides over a period of 6 months. METHODS: Baseline and five consecutive monthly audiological assessments were conducted on 52 adults at a hospital in KwaZulu-Natal...
November 25, 2016: South African Journal of Communication Disorders. die Suid-Afrikaanse Tydskrif Vir Kommunikasieafwykings
https://www.readbyqxmd.com/read/28155204/a-systematic-review-of-the-frequency-and-severity-of-manic-symptoms-reported-in-studies-that-compare-phenomenology-across-children-adolescents-and-adults-with-bipolar-disorders
#9
REVIEW
Faye Ryles, Thomas D Meyer, Jaime Adan-Manes, Iain MacMillan, Jan Scott
BACKGROUND: In the last two decades, there has been a significant increase in the diagnosis of Bipolar Disorder (BD) in children. The notion of prepubertal onsets of BD is not without controversy, with researchers debating whether paediatric cases have a distinct symptom profile or follow a different illness trajectory from other forms of BD. The latter issue is difficult to address without long-term prospective follow-up studies. However, in the interim, it is useful to consider the phenomenology observed in groups of cases with different ages of onset and particularly to compare manic symptoms in children diagnosed with BD compared to cases presenting with BD in adolescence and adulthood...
December 2017: International Journal of Bipolar Disorders
https://www.readbyqxmd.com/read/28125445/self-adjustment-of-upper-electrical-stimulation-levels-in-ci-programming-and-the-effect-on-auditory-functioning
#10
Jantien L Vroegop, J Gertjan Dingemanse, Marc P van der Schroeff, R Mick Metselaar, André Goedegebure
OBJECTIVES: With current cochlear implants (CIs), CI recipients achieve good speech perception in quiet surroundings. However, in acoustically complex, real-life environments, speech comprehension remains difficult and sound quality often remains poor. It is, therefore, a challenge to program CIs for such environments in a clinic. The CI manufacturer Cochlear Ltd. recently introduced a remote control that enables CI recipients to alter the upper stimulation levels of their user programs themselves...
January 17, 2017: Ear and Hearing
https://www.readbyqxmd.com/read/28124068/effect-of-dysarthria-type-speaking-condition-and-listener-age-on-speech-intelligibility
#11
Megan J McAuliffe, Annalise R Fletcher, Sarah E Kerr, Greg A O'Beirne, Tim Anderson
Purpose: The aim of this study was to examine the effect of loud and slow speech cues on younger and older listeners' comprehension of dysarthric speech, specifically, (a) whether one strategy, as opposed to the other, promoted greater intelligibility gains for different speaker groups; (b) whether older and younger listeners' understandings were differentially affected by these strategies; and (c) which acoustic changes best predicted intelligibility gain in individual speakers. Method: Twenty younger and 40 older listeners completed a perceptual task...
February 1, 2017: American Journal of Speech-language Pathology
https://www.readbyqxmd.com/read/28117046/audiologic-and-subjective-evaluation-of-baha-%C3%A2-attract-device
#12
Tomàs Pérez-Carbonell, Ignacio Pla-Gil, Jaume Redondo-Martínez, Antonio Morant-Ventura, Francisco Javier García-Callejo, Jaime Marco-Algarra
We included 9 patients implanted with Baha(®) Attract. All our patients were evaluated by free field tonal audiometry, free field verbal audiometry and free field verbal audiometry with background noise, all the tests were performed with and without the device. To evaluate the subjective component of the implantation, we used the Glasgow Benefit Inventory (GBI) and Abbreviated Profile of Hearing Aid Benefit (APHAB). The auditive assessment with the device showed average auditive thresholds of 35.8dB with improvements of 25...
January 20, 2017: Acta Otorrinolaringológica Española
https://www.readbyqxmd.com/read/28098502/united-kingdom-national-paediatric-bilateral-project-results-of-professional-rating-scales-and-parent-questionnaires
#13
H E Cullington, D Bele, J C Brinton, S Cooper, M Daft, J Harding, N Hatton, J Humphries, M E Lutman, J Maddocks, J Maggs, K Millward, G O'Donoghue, S Patel, K Rajput, V Salmon, T Sear, A Speers, A Wheeler, K Wilson
OBJECTIVES: This fourteen-centre project used professional rating scales and parent questionnaires to assess longitudinal outcomes in a large non-selected population of children receiving simultaneous and sequential bilateral cochlear implants. METHODS: This was an observational non-randomized service evaluation. Data were collected at four time points: before bilateral cochlear implants or before the sequential implant, one year, two years, and three years after...
January 18, 2017: Cochlear Implants International
https://www.readbyqxmd.com/read/28097918/the-hearing-benefit-of-cochlear-implantation-for-individuals-with-unilateral-hearing-loss-but-no-tinnitus
#14
Henryk Skarzynski, Artur Lorens, Marika Kruszynska, Anita Obrycka, Dorota Pastuszak, Piotr Henryk Skarzynski
CONCLUSION: Cochlear implants improve the hearing abilities of individuals with unilateral hearing loss and no tinnitus. The benefit is no different from that seen in patients with unilateral hearing loss and incapacitating tinnitus. OBJECTIVE: To evaluate hearing outcomes after cochlear implantation in individuals with unilateral hearing loss and no tinnitus and compare them to those obtained in a similar group who had incapacitating tinnitus. METHODS: Six cases who did not experience tinnitus before operation and 15 subjects with pre-operative tinnitus were evaluated with a structured interview, a monosyllabic word test under difficult listening situations, a sound localization test, and an APHAB (abbreviated profile of hearing aid benefit) questionnaire...
January 18, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28087804/clinical-selection-strategies-to-identify-ischemic-stroke-patients-with-large-anterior-vessel-occlusion-results-from-sits-istr-safe-implementation-of-thrombolysis-in-stroke-international-stroke-thrombolysis-registry
#15
Jan F Scheitz, Azmil H Abdul-Rahim, Rachael L MacIsaac, Charith Cooray, Heidi Sucharew, Dawn Kleindorfer, Pooja Khatri, Joseph P Broderick, Heinrich J Audebert, Niaz Ahmed, Nils Wahlgren, Matthias Endres, Christian H Nolte, Kennedy R Lees
BACKGROUND AND PURPOSE: The National Institutes of Health Stroke Scale (NIHSS) correlates with presence of large anterior vessel occlusion (LAVO). However, the application of the full NIHSS in the prehospital setting to select patients eligible for treatment with thrombectomy is limited. Therefore, we aimed to evaluate the prognostic value of simple clinical selection strategies. METHODS: Data from the Safe Implementation of Thrombolysis in Stroke International Stroke Thrombolysis Registry (January 2012-May 2014) were analyzed retrospectively...
January 13, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28076344/qualitative-aspects-of-the-process-of-neonatal-hearing-screening-program-in-mexico-evaluated-from-the-parental-perspective
#16
Maria Del Consuelo Martínez Wbaldo, María de Los Ángeles Torres Lagunas
INTRODUCTION: The Universal Newborn Hearing Screening Program in Mexico began in 2010. Its results, published in 2013 by the National Council for the Development and Inclusion of Persons with Disabilities (CONADIS), report low coverage and, currently, there is a dearth of information about its activities. This study describes the process of the program from the epistemological perspective of women whose children participated in the program, evaluating it under the sustenance of the constructivist-respondent model in search of aspects that could help explain its results...
December 12, 2016: Medwave
https://www.readbyqxmd.com/read/28070690/reconstruction-of-defects-of-the-trachea
#17
Margot Den Hondt, Jan Jeroen Vranckx
The trachea has a complex anatomy to fulfill its tasks. Its unique fibro-cartilaginous structure maintains an open conduit during respiration, and provides vertical elasticity for deglutition, mobility of the neck and speech. Blood vessels pierce the intercartilaginous ligaments to perfuse the ciliated epithelium, which ensures effective mucociliary clearance. Removal of a tracheal segment affected by benign or malignant disease requires airtight restoration of the continuity of the tube. When direct approximation of both tracheal ends is no longer feasible, a reconstruction is needed...
February 2017: Journal of Materials Science. Materials in Medicine
https://www.readbyqxmd.com/read/28068407/significant-association-of-urinary-toxic-metals-and-autism-related-symptoms-a-nonlinear-statistical-analysis-with-cross-validation
#18
James Adams, Daniel P Howsmon, Uwe Kruger, Elizabeth Geis, Eva Gehn, Valeria Fimbres, Elena Pollard, Jessica Mitchell, Julie Ingram, Robert Hellmers, David Quig, Juergen Hahn
INTRODUCTION: A number of previous studies examined a possible association of toxic metals and autism, and over half of those studies suggest that toxic metal levels are different in individuals with Autism Spectrum Disorders (ASD). Additionally, several studies found that those levels correlate with the severity of ASD. METHODS: In order to further investigate these points, this paper performs the most detailed statistical analysis to date of a data set in this field...
2017: PloS One
https://www.readbyqxmd.com/read/28054098/-speech-audiometric-assessment-of-informational-masking-german-version
#19
S Rählmann, H Meister
BACKGROUND: In communication situations with multiple speakers, speech recognition is adversely affected by energetic masking (EM) and informational masking (IM). IM characterizes masking effects caused by irrelevant information from competing speakers. This work investigates an approach to assess IM based on the Oldenburg Sentence Test (OLSa). Furthermore, the influence of interaural time differences (ITD) and aging effects on IM are considered. MATERIALS AND METHODS: IM was measured by superimposing two sentences from the OLSa...
January 4, 2017: HNO
https://www.readbyqxmd.com/read/28041786/statistical-evidence-that-a-child-can-create-a-combinatorial-linguistic-system-without-external-linguistic-input-implications-for-language-evolution
#20
REVIEW
Susan Goldin-Meadow, Charles Yang
Can a child who is not exposed to a model for language nevertheless construct a communication system characterized by combinatorial structure? We know that deaf children whose hearing losses prevent them from acquiring spoken language, and whose hearing parents have not exposed them to sign language, use gestures, called homesigns, to communicate. In this study, we call upon a new formal analysis that characterizes the statistical profile of grammatical rules and, when applied to child language data, finds that young children's language is consistent with a productive grammar rather than rote memorization of specific word combinations in caregiver speech...
December 29, 2016: Neuroscience and Biobehavioral Reviews
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