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GBS, Ethiopia

Solomon Assefa, Kassu Desta, Tsehaynesh Lema
BACKGROUND: Group B Streptococcus (GBS) is the leading cause of septicemia, meningitis, and pneumonia in neonates. Maternal colonization with GBS is the principal risk factor for early-onset disease in infants. Group B Streptococcus is now an important cause of maternal and neonatal morbidity and mortality in many parts of the world. In Ethiopia, few studies have been done on GBS colonization among pregnant women. The aim of this study was to determine the prevalence of GBS colonization, antimicrobial susceptibility patterns and assess risk factors among pregnant women...
May 4, 2018: BMC Pregnancy and Childbirth
Tesfaye Assebe Yadeta, Alemayehu Worku, Gudina Egata, Berhanu Seyoum, Dadi Marami, Yemane Berhane
Background: Vertically transmitted group B Streptococcus (GBS) causes fetal and neonatal infections. However, there is limited information on the vertical transmission of GBS in low-income countries. This study, therefore, aimed to determine the rate of vertical transmission of GBS and associated factors among pregnant women in Eastern Ethiopia. Subjects and methods: A cross-sectional, facility-based study was conducted among pregnant women in Harar town, Eastern Ethiopia, from June to October, 2016...
2018: Infection and Drug Resistance
Berhanu Tadesse Ertiro, Kassa Semagn, Biswanath Das, Michael Olsen, Maryke Labuschagne, Mosisa Worku, Dagne Wegary, Girum Azmach, Veronica Ogugo, Tolera Keno, Beyene Abebe, Temesgen Chibsa, Abebe Menkir
BACKGROUND: Molecular characterization is important for efficient utilization of germplasm and development of improved varieties. In the present study, we investigated the genetic purity, relatedness and population structure of 265 maize inbred lines from the Ethiopian Institute of Agricultural Research (EIAR), the International Maize and Wheat Improvement Centre (CIMMYT) and the International Institute of Tropical Agriculture (IITA) using 220,878 single nucleotide polymorphic (SNP) markers obtained using genotyping by sequencing (GBS)...
October 12, 2017: BMC Genomics
Hylemariam Mihiretie Mengist, Olifan Zewdie, Adugna Belew, Regea Dabsu
OBJECTIVE: The main objective of this study was to determine the prevalence and drug susceptibility pattern of group B Streptococci (GBS) among pregnant women. The specific objectives include; (1) To determine the prevalence of GBS colonization among pregnant women (2) To determine the drug susceptibility pattern of GBS among pregnant women and (3) To identify associated risk factors with GBS colonization among pregnant women. RESULTS: The median age of the participants was 24...
August 10, 2017: BMC Research Notes
Abeba Mengist, Hemalatha Kannan, Alemseged Abdissa
BACKGROUND: Streptococcus agalactiae (group B Streptococcus, GBS) is the most frequent pathogen isolated from neonates with invasive bacterial disease and responsible for serious infections in newborns such as pneumonia, septicemia and meningitis. Infection is primarily acquired vertically from mothers colonized with GBS. However, the prevalence and antimicrobial susceptibility pattern of GBS among pregnant women in Ethiopia are less studied. METHODS: This cross-sectional study involved 126 pregnant women at 35-37 weeks of gestation attending the antenatal clinic at Jimma University Hospital...
July 19, 2016: BMC Research Notes
Berhanu Tadesse Ertiro, Veronica Ogugo, Mosisa Worku, Biswanath Das, Michael Olsen, Maryke Labuschagne, Kassa Semagn
BACKGROUND: Quality control (QC) analysis is an important component in maize breeding and seed systems. Genotyping by next-generation sequencing (GBS) is an emerging method of SNP genotyping, which is being increasingly adopted for discovery applications, but its suitability for QC analysis has not been explored. The objectives of our study were 1) to evaluate the level of genetic purity and identity among two to nine seed sources of 16 inbred lines using 191 Kompetitive Allele Specific PCR (KASP) and 257,268 GBS markers, and 2) compare the correlation between the KASP-based low and the GBS-based high marker density on QC analysis...
2015: BMC Genomics
Gebreselassie Alemseged, Selam Niguse, Haftamu Hailekiros, Mehamud Abdulkadir, Muthupandian Saravanan, Tsehaye Asmelash
BACKGROUND: Vaginal colonization with group B Streptococcus (GBS) is the predominant risk factor for the development of invasive neonatal GBS diseases and puts newborns at increased risk for morbidity and mortality. This study is aimed to determine the colonization rate and antimicrobial susceptibility pattern of group B Streptococcus among pregnant women. METHODS: Hospital based cross-sectional study was conducted from August to December 2014 at selected health facilities...
2015: BMC Research Notes
Zufan Lakew Woldu, Tatek Gebreegziabher Teklehaimanot, Sisay Teklu Waji, Mahlet Yigeremu Gebremariam
BACKGROUND: Group B streptococcus (GBS) has been implicated in adverse pregnancy outcomes. GBS recto-vaginal colonization rates significantly vary among different communities and geographic locations. Limited data is available on the prevalence and effects of GBS recto-vaginal colonization among pregnant mothers in developing countries like Ethiopia. OBJECTIVE: To assess the prevalence of GBS recto-vaginal colonization among near term pregnant mothers and the antimicrobial susceptibility pattern of the isolates...
2014: Reproductive Health
Zenebe Melaku, Guta Zenebe, Abera Bekele
This is a ten years retrospective study conducted to assess the clinical profile and outcome of Guillain-Barré Syndrome (GBS) in Ethiopian patients. The medical records of all patients admitted with the diagnosis of GBS to the Department of Internal Medicine, Tikur Anbessa University Hospital, Addis Ababa, Ethiopia during the period September 1992 to September 2001 were reviewed. During the ten-year review period ninety-five patients were admitted with the diagnosis of GBS, of which eighty-one met the National Institute of Neurological and Communicative Disorders and Stroke diagnostic criteria...
January 2005: Ethiopian Medical Journal
E Halle, J Schmidt, H Halle, E Günther, M Taha
The importance of neonatal septicemia and meningitis caused by group B streptococci (GBS) has risen worldwide in the last ten years. Between January and June 1987 200 nonselected intrapartum women at Gondar College of Medical Sciences were examined for GBS colonization. One rectal and vaginal swab was collected from each woman and cultured in 5% sheepblood agar. Cultures also from 80 newborns were obtained from throat and ear. The colonization rate of women was 9.0%. 5% of the newborns were positive for GBS...
1988: Zentralblatt Für Gynäkologie
B Ghiorgis
A two year retrospective study of 242 neonates with a clinical diagnosis of neonatal sepsis was undertaken. The neonates on whom blood culture results were available for analysis were categorized into "proven" or "presumptive" sepsis. A changing pattern in aetiological pathogens is identified. The conspicuous absence of Group B Streptococcal (GBS) sepsis is discussed. The overall mortality rate was 37% but the mortality rate in the bacteraemic patients was only 22.6%. This discrepancy is discussed in detail and further prospective study suggested...
October 1991: Ethiopian Medical Journal
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