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Capsulitis

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https://www.readbyqxmd.com/read/28550275/detection-of-small-bowel-tumor-in-wireless-capsule-endoscopy-images-using-an-adaptive-neuro-fuzzy-inference-system
#1
Alizadeh Mahdi, Haji Maghsoudi Omid, Sharzehi Kaveh, Reza Hemati Hamid, Kamali Asl Alireza, Talebpour Alireza
Automatic diagnosis tool helps physicians to evaluate capsule endoscopic examinations faster and more accurate. The purpose of this study was to evaluate the validity and reliability of an automatic post-processing method for identifying and classifying wireless capsule endoscopic images, and investigate statistical measures to differentiate normal and abnormal images. The proposed technique consists of two main stages, namely, feature extraction and classification. Primarily, 32 features incorporating four statistical measures (contrast, correlation, homogeneity and energy) calculated from co-occurrence metrics were computed...
May 26, 2017: Journal of Biomedical Research
https://www.readbyqxmd.com/read/28549907/transformation-of-bcs-class-i-and-iii-drugs-into-ionic-liquids-and-lipophilic-salts-for-enhanced-developability-using-lipid-formulations
#2
Hywel D Williams, Leigh Ford, Shea Lim, Sifei Han, John Baumann, Hannah Sullivan, David Vodak, Annabel Igonin, Hassan Benameur, Colin W Pouton, Peter J Scammells, Christopher J H Porter
Higher lipid solubility of lipophilic salt forms creates new product development opportunities for high-dose liquid-filled capsules. The purpose of this study was to determine if lipophilic salts of BCS Class I amlodipine and BCS Class III fexofenadine, ranitidine and metformin were better lipid formulation candidates than existing commercial salts. Lipophilic salts were prepared from lipophilic anions and commercial HCl or besylate salt forms, as verified by (1)H NMR. Thermal properties were assessed by DSC and hot-stage microscopy...
May 23, 2017: Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28549885/the-radial-approach-to-the-wrist-with-styloidectomy-a-cadaver-study
#3
F-A Lecoq, A Sébilo, P Bellemère
The radial approach to the wrist is already used in several surgical techniques such as radial styloidectomy and Zaidemberg's vascularized radial graft. The aim of our work was to describe the surgical anatomy of that approach and to determine the acceptable limits of radial oblique styloidectomy that does not damage the anterior and posterior radiocarpal ligaments. This radial approach was performed on 11 cadaver specimens. The superficial branches of the radial nerve and the antebrachial cephalic vein were carefully located in the superficial plane...
May 23, 2017: Hand Surgery and Rehabilitation
https://www.readbyqxmd.com/read/28549773/cochlear-implantation-in-patients-with-otosclerosis-of-the-otic-capsule
#4
Jay Burmeister, Susan Rathgeb, Jacques Herzog
OBJECTIVE: To evaluate outcomes of cochlear implantation of patients with otosclerosis of the otic capsule. STUDY DESIGN: A retrospective case series of 6 patients (7 ears). PATIENTS: 6 patients (7 ears), 5 patients with severe to profound sensorineural hearing loss; 1 patient with mild to profound sensorineural hearing loss, with radiologic evidence of otosclerosis. All patients were adult males, with or without history of stapes surgery...
May 19, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28549284/long-term-results-of-the-toefit-plus-replacement-for-first-metatarsophalangeal-joint-arthritis
#5
REVIEW
Shreekant Gupta, Saqib Masud
Hallux rigidus is osteoarthritis affecting the metatarsophalangeal joint of the first toe. Patients often complain of pain and stiffness with pain being aggravated by walking, particularly during toe-off in the gait cycle. Osteoarthritis of the metatarsophalangeal joint is commonly treated with arthrodesis or resection arthroplasty. Metallic replacement of this joint is used sometimes but is not widely accepted. The use of silastic joints has problems with synovitis and implant failure. The authors used titanium implants, which can be screwed into the metatarsal and phalanx, allowing good fixation without the use of bone cement...
May 8, 2017: Foot
https://www.readbyqxmd.com/read/28548820/preparation-of-microcapsules-containing-benzoyl-peroxide-initiator-with-gelatin-gum-arabic-polyurea-formaldehyde-shell-and-evaluating-their-storage-stability
#6
Maryam Raeesi, S Mojtaba Mirabedini, Ramin R Farnood
This work involves the optimized preparation and characterization of microcapsules which contain benzoyl peroxide (BPO) dispersed in dibutyl phthalate (DBP) with gelatin-gum arabic (Gel-GA)/Polyurea-formaldehyde (PUF) shell. The microcapsules were prepared in two steps using complex coacervation and in situ polymerization techniques, respectively, at various mixing speeds and different core:shell ratios. The scanning electron microscopy (SEM), optical microscopy, and Fourier transform infrared (FTIR) spectroscopy were used for characterization of prepared microcapsules...
May 26, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28548819/tuning-the-properties-of-polymer-capsules-for-cellular-interactions
#7
Huanli Sun, Jiwei Cui, Yi Ju, Xi Chen, Edgar H H Wong, Jenny Tran, Greg G Qiao, Frank Caruso
Particle-cell interactions are governed by, among other factors, the composition and surface properties of the particles. Herein, we report the preparation of various polymer capsules with different compositions and properties via atom transfer radical polymerization mediated continuous assembly of polymers (CAPATRP), where the cellular interactions of these capsules, particularly fouling and specific targeting, are examined by flow cytometry and deconvolution microscopy. Acrylated eight-arm poly(ethylene glycol) (8-PEG) and poly(N-(2-hydroxypropyl)-methacrylamide) (PHPMA) as well as methacrylated hyaluronic acid (HA), poly(glutamic acid) (PGA), and poly(methacrylic acid) (PMA) are used as macro-cross-linkers to obtain a range of polymer capsules with different compositions (PEG, PHPMA, HA, PGA, and PMA)...
May 26, 2017: Bioconjugate Chemistry
https://www.readbyqxmd.com/read/28548561/effect-of-honey-and-royal-jelly-against-cisplatin-induced-nephrotoxicity-in-patients-with-cancer
#8
Hasnaa Osama, Aya Abdullah, Bassma Gamal, Dina Emad, Doha Sayed, Eman Hussein, Eman Mahfouz, Joy Tharwat, Sally Sayed, Shrouk Medhat, Treza Bahaa, Mohamed E A Abdelrahim
OBJECTIVES: Cisplatin constitutes one of the most potent antineoplastic drugs; however, nephrotoxicity limited its eligibility for optimal clinical use. This study was designed to evaluate the role of honey and royal jelly with antioxidant properties in the protection of cisplatin-induced acute kidney injury in patients with cancer. METHODS: Patients with cancer assigned for cisplatin chemotherapy were randomly divided into bee honey and royal jelly groups pretreated before the initiation and during cisplatin chemotherapeutic regimen and control group on cisplatin only...
May 26, 2017: Journal of the American College of Nutrition
https://www.readbyqxmd.com/read/28548161/click-co-sandwich-terminated-dendrimers-as-polyhydride-reservoirs-and-micellar-templates
#9
Amalia Rapakousiou, Colette Belin, Lionel Salmon, Jaime Ruiz, Didier Astruc
Neutral click metallodendrimers with [Co(I)(η(4)-cyclopentadiene)(η(5)-cyclopentadienyl)] termini are synthesized by reduction of dendrimers with 9, 27 or 81 cobalticenium termini and serve as polyhydride reservoirs and reductants; for instance, they reduce proton sources to H2 and Au(III) to micellized capsules of gold nanoparticles.
May 26, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28547723/capsule-commentary-on-blumenthal-et-al-using-a-self-reported-global-health-measure-to-identify-patients-at-high-risk-for-future-healthcare-utilization
#10
Joel Papak, Joseph Chiovaro
No abstract text is available yet for this article.
May 25, 2017: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/28547137/age-dependent-arthrosonographic-reference-values-of-the-hip-joint-in-healthy-children-and-adolescents-a-cross-sectional-multicenter-ultrasound-study
#11
Ralf Felix Trauzeddel, Hartwig Lehmann, Daniel Windschall, Gerd Ganser, Rainer Berendes, Maria Haller, Manuela Krumrey-Langkammerer, Katharina Palm-Beden, Antje Nimtz-Talaska, Christine Nirschl, Phillip Schoof, Ralf Trauzeddel
BACKGROUND: Musculoskeletal US is a noninvasive imaging method for diagnosing and monitoring inflammatory rheumatic diseases. OBJECTIVES: To develop age- and gender-related arthrosonographic reference intervals for the hip joint of healthy children and adolescents. MATERIALS AND METHODS: In a cross-sectional US study, we examined both hip joints of 445 children and adolescents with an age range of 1 year to 18 years. We measured the distance between the bone surface and the outer margin of the joint capsule to define the bone-capsule distance, the joint capsule and cartilage thickness, and the capsule layer thickness...
May 25, 2017: Pediatric Radiology
https://www.readbyqxmd.com/read/28546803/effect-of-tribulus-terrestris-ginger-saffron-and-cinnamomum-on-menopausal-symptoms-a-randomised-placebo-controlled-clinical-trial
#12
Simin Taavoni, Neda Nazem Ekbatani, Hamid Haghani
Menopausal symptoms experienced by women vary widely, and while many women transition through menopause with manageable symptoms, others experience severe symptoms, which may impair their quality of life. The purpose of this study was to determine the effect of Tribulus terrestris, ginger, saffron, and Cinnamomum on menopausal symptoms. A randomised, triple-blind, controlled trial design was used for this study. The participants were 80 postmenopausal women aged 50-60 years. A demographic data form and the Menopause Rating Scale were used to collect data...
March 2017: Przeglad Menopauzalny, Menopause Review
https://www.readbyqxmd.com/read/28546087/region-specific-oligodendrocyte-transcription-factor-expression-in-a-model-of-neonatal-hypoxic-injury
#13
Bethann M Affeldt, Andre Obenaus, Jonathan Chan, Andrea C Pardo
White matter injury (WMI) of prematurity is associated with a spectrum of neurological disorders ranging from mild cognitive and behavioral deficits to cerebral palsy. Translational studies have implicated impaired oligodendrocyte development after hypoxia as the primary cause of WMI, but the underlying mechanisms remain poorly understood. The goal of this study was to identify alterations in the expression of oligodendrocyte precursor cell transcription factors in a mouse model of transient mild global hypoxia...
May 22, 2017: International Journal of Developmental Neuroscience
https://www.readbyqxmd.com/read/28545723/emergence-of-a-urogenital-pathotype-of-neisseria-meningitidis
#14
Charlene M Kahler
Neisseria meningitidis is the causative agent of transmissible sepsis and meningitis in humans. A urogenital pathotype of N. meningitidis as the causative agent of transmissible urethritis in the USA has been recently characterised. This pathotype belongs to clonal complex 11 and has lost capsule production but gained anaerobic growth.
May 22, 2017: Trends in Microbiology
https://www.readbyqxmd.com/read/28544505/understanding-the-mechanisms-of-gold-shell-growth-onto-polymer-microcapsules-to-control-shell-thickness
#15
Alison Louise Tasker, James Hitchcock, Elaine Alice Baxter, Olivier Cayre, Simon Biggs
Polymer microcapsules have been used commercially for decades, however they have an inherent flaw which renders them impractical as a carrier of small, volatile molecules. The porous nature of the polymer shell allows for diffusion of the encapsulated molecules into the bulk. The use of metal shells is an innovative way to prevent undesired loss of small molecules from the core of microcapsules, however it is important, particularly when using expensive metals to ensure that the resulting shell is as thin as possible...
May 21, 2017: Chemistry, An Asian Journal
https://www.readbyqxmd.com/read/28543613/comparative-pharmacokinetics-of-acteoside-from-total-glycoside-extracted-from-leaves-of-rehmannia-and-dihuangye-total-glycoside-capsule-in-normal-and-diabetic-nephropathy-rats
#16
Xin-Xin Dai, Shu-Lan Su, Hong-Die Cai, Dan-Dan Wei, Tian-Yao Zheng, Zhen-Hua Zhu, Hui Yan, Er-Xin Shang, Sheng Guo, Da-Wei Qian, Jin-Ao Duan
Rehmannia glutinosa Libosch (RG), is officially listed in the Chinese Pharmacopoeia and is widely used in China. In this paper, a sensitive and rapid ultra-performance liquid chromatography-mass spectrometry (UPLC-TQ-MS) including multiple-reaction monitoring mode was developed and applied to study the pharmacokinetics effect of acteoside from Total glycoside Extracted from Leaves of Rehmannia (TLR) and Dihuangye total glycoside capsule (DTG) in normal and diabetic nephropathy rats. Diabetic nephropathy rats model was induced by intraperitoneal injection of a small dose of streptozotocin and high-fat diet and plus 5% glucose drinking water...
May 23, 2017: Biomedical Chromatography: BMC
https://www.readbyqxmd.com/read/28542452/the-role-of-aspartyl-aminopeptidase-ape4-in-cryptococcus-neoformans-virulence-and-authophagy
#17
Fabiano de Assis Gontijo, Amanda Teixeira de Melo, Renata C Pascon, Larissa Fernandes, Hugo Costa Paes, J Andrew Alspaugh, Marcelo A Vallim
In order to survive and cause disease, microbial pathogens must be able to proliferate at the temperature of their infected host. We identified novel microbial features associated with thermotolerance in the opportunistic fungal pathogen Cryptococcus neoformans using a random insertional mutagenesis strategy, screening for mutants with defective growth at 37°C. Among several thermosensitive mutants, we identified one bearing a disruption in a gene predicted to encode the Ape4 aspartyl aminopeptidase protein...
2017: PloS One
https://www.readbyqxmd.com/read/28541773/induction-of-salivary-gland-like-cells-from-dental-follicle-epithelial-cells
#18
Q L Xu, A Furuhashi, Q Z Zhang, C M Jiang, T-H Chang, A D Le
The dental follicle (DF), most often associated with unerupted teeth, is a condensation of ectomesenchymal cells that surrounds the tooth germ in early stages of tooth development. In the present study, we aim to isolate epithelial stem-like cells from the human DF and explore their potential differentiation into salivary gland (SG) cells. We demonstrated the expression of stem cell-related genes in the epithelial components of human DF tissues, and these epithelial progenitor cells could be isolated and ex vivo expanded in a reproducible manner...
May 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28541681/platelet-microcapsule-hybrids-leverage-contractile-force-for-targeted-delivery-of-hemostatic-agents
#19
Caroline E Hansen, David R Myers, Wallace Hunter Baldwin, Yumiko Sakurai, Shannon L Meeks, L Andrew Lyon, Wilbur A Lam
We report a cell-mediated, targeted drug delivery system utilizing polyelectrolyte multilayer capsules that hybridize with the patient's own platelets upon intravenous administration. The hybridized platelets function as the sensor and actuator for targeted drug delivery and controlled release in our system. These capsules are biochemically and mechanically tuned to enable platelet adhesion and capsule rupture upon platelet activation and contraction, enabling the targeted and controlled "burst" release of an encapsulated biotherapeutic...
May 25, 2017: ACS Nano
https://www.readbyqxmd.com/read/28541041/self-assembled-zno-nanoparticle-capsules-for-carrying-and-delivering-isotretinoin-to-cancer-cells
#20
Wei Zhao, Ji-Shi Wei, Peng Zhang, Jie Chen, Ji-Lie Kong, Lian-Hua Sun, Huan-Ming Xiong, Helmuth Möhwald
ZnO@polymer core-shell nanoparticles are assembled into novel capsule shells with diameters of about 100 nm to load isotretinoin (ISO) with a capacity as high as 34.6 wt %. Although ISO, a widely used drug for acne treatment, by itself is not suitable for treating cancer because of its hydrophobicity, our ZnO-ISO composite showed much stronger anticancer activity. The improved cytotoxicity is ascribed to the synergistic effects of the ZnO@polymer and ISO, where the ZnO@polymer helps in the accumulation of ISO in cancer cells on the one hand, and on the other hand, ISO is released completely through ZnO decomposition under acidic conditions of cancer cells...
May 25, 2017: ACS Applied Materials & Interfaces
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