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incidence takotsubo

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https://www.readbyqxmd.com/read/28593334/seasonal-variation-in-patient-characteristics-and-in-hospital-outcomes-of-takotsubo-syndrome-a-nationwide-retrospective-cohort-study-in-japan
#1
Toshiaki Isogai, Hiroki Matsui, Hiroyuki Tanaka, Kiyohide Fushimi, Hideo Yasunaga
Although there is reportedly seasonal variation in the occurrence of Takotsubo syndrome (TTS), it is unknown whether there is a relationship between season and patient characteristics, or whether season influences outcomes. Using the Diagnosis Procedure Combination database in Japan, we retrospectively identified 4306 patients (mean age 73.6 years) hospitalized with TTS between January 2011 and December 2013. We divided patients into four groups according to season of admission [n = 914, Spring (March-May); n = 1243, Summer (June-August); n = 1245, Autumn (September-November); n = 904, Winter (December-February)]...
June 7, 2017: Heart and Vessels
https://www.readbyqxmd.com/read/28417437/cumulative-impact-of-stressful-life-events-on-the-development-of-takotsubo-cardiomyopathy
#2
Lindsey Rosman, Shira Dunsiger, Elena Salmoirago-Blotcher
BACKGROUND: The role of stressful life events in the onset of Takotsubo cardiomyopathy (TC) is unclear. PURPOSE: This study sought to examine associations between type, timing, and number of stressful life events and onset of TC. METHODS: A case-control study conducted among consecutive incident female TC cases and myocardial infarction (MI) controls admitted to two emergency departments in New England. Healthy female controls (HC) were recruited from a volunteers' registry...
April 17, 2017: Annals of Behavioral Medicine: a Publication of the Society of Behavioral Medicine
https://www.readbyqxmd.com/read/28367338/folfox-induced-takotsubo-cardiomyopathy-treated-with-impella-assist-device
#3
Swethika Sundaravel, Abdulah Alrifai, Mohamad Kabach, Waqas Ghumman
Chemotherapy induced cardiotoxicity is becoming increasingly prevalent with several new agents being used recently. The incidence of Takotsubo cardiomyopathy due to 5-fluorouracil based chemotherapeutic regimens like FOLFOX is not uncommon. It is also seen with platinum based chemotherapy. Most of these patients have reversible cardiotoxicity and the cardiac function recovers within a short period with supportive treatment. Here we have a patient who presented with cardiogenic shock after 5 days of receiving FOLFOX regimen for colorectal adenocarcinoma...
2017: Case Reports in Cardiology
https://www.readbyqxmd.com/read/28340038/coincidental-coronary-artery-disease-impairs-outcome-in-patients-with-takotsubo-cardiomyopathy
#4
V Bill, I El-Battrawy, K Schramm, U Ansari, U Hoffmann, D Haghi, J Kuschyk, M Borggrefe, I Akin
Background and aim: Takotsubo cardiomyopathy (TC) is an important differential diagnosis of coronary artery disease (CAD), mimicking acute coronary syndrome in clinical symptoms, biomarker profiles and ST-elevation in ECG. Absence of occlusive coronary disease is an essential criterion distinguishing both diseases. The aim of the study was to explore the influence of co-existing incidental CAD on poorer clinical outcomes and all-cause mortality in TC. Design, methods and results: Our mono-centric study cohort constituted 114 consecutive patients diagnosed with TC between 2003 and 2015...
March 14, 2017: QJM: Monthly Journal of the Association of Physicians
https://www.readbyqxmd.com/read/28289555/gender-differences-in-post-traumatic-stress
#5
Maria Grazia Modena, Daniele Pettorelli, Giulia Lauria, Elisa Giubertoni, Erminio Mauro, Valentina Martinotti
Acute stress can trigger cardiovascular events and disease. The earthquake is an "ideal" natural experiment for acute and chronic stress, with impact mainly on the cardiovascular system. On May 20th and 29th, 2012, two earthquakes of magnitude 5.9° to 6.4° on the Richter scale, hit the province of Modena and Reggio Emilia, an area of the north-center of Italy never considered at seismic risk. The purpose of our study was to assess whether there were gender-specific differences in stress-induced incidence of cardiovascular events and age of patients who arrived at the Emergency Departments (ED) of the three main teaching hospitals of the University of Modena and Reggio Emilia...
2017: BioResearch Open Access
https://www.readbyqxmd.com/read/28210509/recurrence-of-postoperative-stress-induced-cardiomyopathy-resulting-from-status-epilepticus
#6
Grant A Miller, Yousef M Ahmed, Nicki S Tarant
Introduction. Classically, stress-induced cardiomyopathy (SIC), also known as takotsubo cardiomyopathy, displays the pathognomonic feature of reversible left ventricular apical ballooning without coronary artery stenosis following stressful event(s). Temporary reduction in ejection fraction (EF) resolves spontaneously. Variants of SIC exhibiting mid-ventricular regional wall motion abnormalities have been identified. Recent case series present SIC as a finding in association with sudden unexplained death in epilepsy (SUDEP)...
2017: Case Reports in Critical Care
https://www.readbyqxmd.com/read/28133464/clinical-and-echocardiographic-analysis-of-patients-suffering-from-recurrent-takotsubo-cardiomyopathy
#7
Ibrahim El-Battrawy, Uzair Ansari, Michael Behnes, Dennis Hillenbrand, Katja Schramm, Darius Haghi, Ursula Hoffmann, Theano Papavassiliu, Elif Elmas, Christian Fastner, Tobias Becher, Stefan Baumann, Christina Dösch, Felix Heggemann, Jürgen Kuschyk, Martin Borggrefe, Ibrahim Akin
BACKGROUND: Recurrence of takotsubo cardiomyopathy (TTC) is a well-known complication. However, current literature lists only a few isolated cases. We aimed to determine the incidence and clinical significance of recurrent TTC. METHODS & RESULTS: Our institutional database constituted a collective of 114 patients diagnosed with TTC since 2003. Close follow-up of these patients revealed a recurrence of TTC in seven of these (6.1%). The time interval between the index event and its recurrence varied between six months and six years...
November 2016: Journal of Geriatric Cardiology: JGC
https://www.readbyqxmd.com/read/27852798/clinical-presentations-and-outcomes-of-takotsubo-syndrome-in-the-setting-of-subarachnoid-hemorrhage-a-systematic-review-and-meta-analysis
#8
Akram Y Elgendy, Islam Y Elgendy, Hend Mansoor, Ahmed N Mahmoud
BACKGROUND: Evidence remains inconsistent regarding the incidence and prognosis of Takotsubo syndrome in the setting of subarachnoid hemorrhage. Thus, we aimed to evaluate the clinical presentation and in-hospital mortality of these patients. METHODS: A systematic review of the electronic databases was conducted for studies involving patients with spontaneous subarachnoid hemorrhage and concomitant findings of classical Takotsubo syndrome on transthoracic echocardiogram...
November 16, 2016: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/27752409/the-first-case-of-severe-takotsubo-cardiomyopathy-associated-with-5-fluorouracil-in-a-patient-with-abnormalities-of-both-dihydropyrimidine-dehydrogenase-dpyd-and-thymidylate-synthase-tyms-genes
#9
Muhammad W Saif, Melissa Smith, Antonio Maloney
5-Fluorouracil (5-FU) is the backbone of the chemotherapy regimens approved for treatment of many malignancies, especially colorectal cancer (CRC). The incidence of cardiotoxicity associated with 5-FU ranges between 1.5% to 18% and is most commonly manifested as anginal symptoms. Cardiomyopathy is very rarely reported with 5-FU and capecitabine. A 35-year-old Caucasian male with T3, N1, M0 rectal cancer after the initial neoadjuvant chemoradiation with 5FU/LV followed by surgical abdominoperineal resection (APR), began mFOLFOX6 in the adjuvant setting...
September 14, 2016: Curēus
https://www.readbyqxmd.com/read/27742423/reproductive-history-of-women-with-takotsubo-cardiomyopathy
#10
Elena Salmoirago-Blotcher, Shira Dunsiger, Heather H Swales, Gerard P Aurigemma, Ira Ockene, Lindsey Rosman, Ilan S Wittstein
Takotsubo cardiomyopathy (TC) occurs predominantly in postmenopausal women, suggesting a possible role of reproductive and hormonal factors in the pathophysiology of this condition. Yet reproductive characteristics of women with TC have received limited attention. This prospective case-control study sought to explore reproductive characteristics associated with TC. Incident TC cases and myocardial infarction (MI) controls were recruited among consecutive women presenting at the emergency departments of 2 large medical centers in Massachusetts and Connecticut...
December 15, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/27719650/the-insular-cortex-and-takotsubo-cardiomyopathy
#11
Michiaki Nagai, Keigo Dote, Masaya Kato, Shota Sasaki, Noboru Oda, Eisuke Kagawa, Yoshinori Nakano, Aya Yamane, Tasuku Higashihara, Shunsuke Miyauchi, Akane Tsuchiya, Wakako Harada, Kazuomi Kario
Transient left ventricular dysfunction in patients under emotional stress, also known as Takotsubo cardiomyopathy, has been recognized as a distinct clinical entity. Recent studies have supported the concept notion that the cardiovascular system is regulated by cortical modulation. A network consisting of the insular cortex (Ic), anterior cingulate gyrus, and amygdala plays a crucial role in the regulation of the central autonomic nervous system in relation to emotional stress such as anxiety, fear and sadness...
2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/27680775/serum-interleukin-6-and-10-levels-in-takotsubo-cardiomyopathy-increased-admission-levels-may-predict-adverse-events-at-follow-up
#12
Francesco Santoro, Nicola Tarantino, Armando Ferraretti, Riccardo Ieva, Francesco Musaico, Francesca Guastafierro, Luigi Di Martino, Matteo Di Biase, Natale Daniele Brunetti
BACKGROUND AND AIMS: Systemic inflammation has been hypothesized as a possible mechanism of Takotsubo cardiomyopathy (TTC). Aim of the study was to assess the role of interleukin (IL)-6 and IL-10 in subjects with an episode of TTC. METHODS: Fifty-six consecutive subjects with TTC were prospectively enrolled in the study and followed for a mean of 178 days. Circulating levels of IL-6, IL-10, clinical condition and left ventricular ejection fraction were evaluated at admission...
September 10, 2016: Atherosclerosis
https://www.readbyqxmd.com/read/27679934/development-and-validation-of-a-simple-integer-risk-score-for-prediction-of-in-hospital-mortality-following-takotsubo-syndrome
#13
MULTICENTER STUDY
Ahmed N Mahmoud, Mohammad Al-Ani, Marwan Saad, Akram Y Elgendy, Islam Y Elgendy
BACKGROUND: Data regarding the characteristics associated with worse outcomes in Takotsubo syndrome (TTS) patients is lacking. METHODS AND OBJECTIVES: The National Inpatient Sample (NIS) 2012 database was utilized to calculate a risk score for in-hospital mortality following TTS that was internally and externally validated in both 2012 and 2013 databases, respectively. RESULTS: The incidences of in-hospital mortality in the 2012 development sample were 0...
November 2016: Heart & Lung: the Journal of Critical Care
https://www.readbyqxmd.com/read/27678209/incidence-and-predictors-of-stroke-during-the-index-event-in-an-ethnically-diverse-takotsubo-cardiomyopathy-population
#14
A Dias, E Franco, S Janzer, Nikoloz Koshkelashvili, V Bhalla, Manolo Rubio, Sarah Amanullah, Kathy Hebert, Vincent M Figueredo
Takotsubo cardiomyopathy (TTS) is a peculiar clinical condition often affecting postmenopausal women after a stressful trigger. The underlying mechanisms have not been completely elucidated but several hypotheses have been advanced, with catecholamine cardiotoxicity, microvascular dysfunction and coronary artery spasm each suggested to play a role. The incidence of stroke after TTS appears to range from 0% to 7.7%, and interestingly TTS has been described as both a cause and a complication of stroke. We sought to assess the incidence and predictors of stroke during the index event (peri-index event stroke) in a heterogeneous TTS population...
July 2016: Functional Neurology
https://www.readbyqxmd.com/read/27666410/incidence-and-predictors-of-stroke-during-the-index-event-in-an-ethnically-diverse-takotsubo-cardiomyopathy-population
#15
A Dias, E Franco, S Janzer, Nikoloz Koshkelashvili, V Bhalla, Manolo Rubio, Sarah Amanullah, Kathy Hebert, Vincent M Figueredo
Takotsubo cardiomyopathy (TTS) is a peculiar clinical condition often affecting postmenopausal women after a stressful trigger. The underlying mechanisms have not been completely elucidated but several hypotheses have been advanced, with catecholamine cardiotoxicity, microvascular dysfunction and coronary artery spasm each suggested to play a role. The incidence of stroke after TTS appears to range from 0% to 7.7%, and interestingly TTS has been described as both a cause and a complication of stroke. We sought to assess the incidence and predictors of stroke during the index event (peri-index event stroke) in a heterogeneous TTS population...
September 26, 2016: Functional Neurology
https://www.readbyqxmd.com/read/27553636/psychiatric-history-post-discharge-distress-and-personality-characteristics-among-incident-female-cases-of-takotsubo-cardiomyopathy-a-case-control-study
#16
Elena Salmoirago-Blotcher, Lindsey Rosman, Ilan S Wittstein, Shira Dunsiger, Heather H Swales, Gerard P Aurigemma, Ira S Ockene
BACKGROUND: The role of psychological factors in the onset of takotsubo cardiomyopathy (TC) is still controversial. Associations with previous psychiatric conditions are registry-based; associations with personality characteristics and psychological sequelae of TC have been largely unexplored. This case-control study sought to study pre-admission psychiatric morbidity, personality traits, and post-discharge distress in incident cases of TC. METHODS: TC cases (Mayo clinic criteria) and acute myocardial infarction (MI) controls were recruited among women admitted to two Emergency Departments in New England...
November 2016: Heart & Lung: the Journal of Critical Care
https://www.readbyqxmd.com/read/27429563/prevalence-clinical-characteristics-and-predictors-of-patients-with-thromboembolic-events-in-takotsubo-cardiomyopathy
#17
Ibrahim El-Battrawy, Michael Behnes, Dennis Hillenbrand, Darius Haghi, Ursula Hoffmann, Theano Papavassiliu, Siegfried Lang, Christian Fastner, Tobias Becher, Stefan Baumann, Felix Heggemann, Jürgen Kuschyk, Martin Borggrefe, Ibrahim Akin
BACKGROUND: Several acute complications related to takotsubo cardiomyopathy (TTC) have been documented recently. However, the incidence and clinical significance of acute thromboembolic events in TTC is not well established. METHODS: A detailed investigation of the clinical characteristics and in-hospital complications of 114 consecutive patients diagnosed with TTC between January 2003 and September 2015 was carried out. This study was initiated to reveal the predictors, clinical significance, and short-term and long-term outcomes of patients with TTC associated with acute thromboembolic events on index presentation...
2016: Clinical Medicine Insights. Cardiology
https://www.readbyqxmd.com/read/27122689/comparison-of-clinical-features-between-typical-and-atypical-takotsubo-cardiomyopathy-a-single-center-retrospective-case-controlled-study
#18
Cheng-Kang Chen, Cheng-Yun Chen, Yung-Ping Chen, Rei-Yeuh Chang
BACKGROUND: The incidence and possible differences between typical and atypical Takotsubo cardiomyopathy (TTC) in Taiwanese patients have not yet been assessed. METHODS: We reviewed the records of 2171 patients who underwent left heart catheterization for suspected acute coronary syndrome (ACS) between January 2003 and March 2011 to identify TTC. Demographic, clinical presentations, laboratory data, and electrocardiographic, echocardiographic and angiographic findings were assessed in all patients...
January 2013: Acta Cardiologica Sinica
https://www.readbyqxmd.com/read/27064298/incidence-and-patterns-of-cardiomyopathy-in-carbon-monoxide-poisoned-patients-with-myocardial-injury
#19
Yong Sung Cha, Hyun Kim, Sung Oh Hwang, Jang Young Kim, Yun Kwon Kim, Eun Hee Choi, Oh Hyun Kim, Hyung Il Kim, Kyoung Chul Cha, Kang Hyun Lee
OBJECTIVES: Sustained myocardial injury is a significant predictor of mortality in carbon monoxide (CO) poisoning. There are few reports in the literature regarding the presence of CO-induced cardiomyopathy from early stages in the emergency department (ED). We prospectively investigated the early incidence of CO-induced cardiomyopathy and its patterns in patients with cardiomyopathy. MATERIALS AND METHODS: During a 10-month period, transthoracic echocardiography (TTE) was performed in 43 consecutive patients with CO poisoning and myocardial injury, which was defined as elevated high-sensitive troponin I within 24 h after ED arrival...
July 2016: Clinical Toxicology
https://www.readbyqxmd.com/read/26960685/therapeutic-outcomes-for-patients-with-aneurysmal-subarachnoid-hemorrhage-complicated-by-takotsubo-cardiomyopathy
#20
Joji Inamasu, Tsukasa Ganaha, Shunsuke Nakae, Tatsuo Ohmi, Akira Wakako, Riki Tanaka, Kiyonori Kuwahara, Hirotaka Kogame, Yushi Kawazoe, Tadashi Kumai, Motoharu Hayakawa, Yuichi Hirose
BACKGROUND: There are no guidelines regarding the optimal treatment of subarachnoid hemorrhage (SAH) patients complicated by Takotsubo cardiomyopathy (TCM). Although coiling has been favored as the first-line treatment, clipping may also be indicated in patients with ruptured middle cerebral artery aneurysms or in those with massive intracerebral hemorrhage. The study objective is (1) to report the feasibility/safety of clipping/coiling and (2) to identify possible prognosticators in that population...
May 2016: Acta Neurochirurgica
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