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https://www.readbyqxmd.com/read/29020214/how-well-do-neurologic-symptoms-identify-individuals-with-neurosyphilis
#1
Arielle P Davis, Joshua Stern, Lauren Tantalo, Sharon Sahi, Sarah Holte, Shelia Dunaway, Christina M Marra
Background: Current guidelines recommend lumbar puncture (LP) in patients with syphilis who have neurologic syndromes. Methods: 81 HIV-uninfected individuals and 385 HIV-infected individuals enrolled in a study of cerebrospinal fluid (CSF) abnormalities in syphilis underwent LP and a structured symptom history, including assessment of headache; stiff neck; photophobia; ocular inflammation; vision, hearing or sensory loss; or gait incoordination. Neurosyphilis was defined as a reactive CSF-Venereal Disease Research Laboratory (VDRL) test...
September 9, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28980302/a-retrospective-study-of-the-prevalence-and-outcomes-of-syphilis-in-pregnancy-in-a-five-year-period
#2
Emily D Ebenezer, Santosh J Benjamin, Rani D Sahni, John Aj Prakash, Hepsy Chelliah, Jiji E Mathews
OBJECTIVE: To determine the prevalence of syphilis in pregnancy and to assess the effect of syphilis on maternal and perinatal outcomes. METHODS: In a retrospective study, data were reviewed for pregnant women who tested positive for syphilis during routine prenatal screening at a center in India between January 2011 and December 2015. Women with both a positive venereal disease research laboratory (VDRL) test and a positive Treponema pallidum hemagglutination assay (TPHA) were considered to have syphilis, and their maternal and fetal outcomes were assessed...
October 5, 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/28966492/seroprevalence-of-transfusion-transmitted-infections-in-healthy-blood-donors-a-5-year-tertiary-care-hospital-experience
#3
Sushama A Chandekar, Gaythri P Amonkar, Heena M Desai, Nitin Valvi, Gururaj V Puranik
INTRODUCTION: Transfusion transmitted infections (TTIs) can cause threat to bloody safety as blood transfusion is an important mode of transmission of TTI to the recipient, hence, to prevent transmission of these diseases, screening tests on blood bags is an important step for blood safety. AIM: This study was undertaken with the aim of determining the seroprevalence of TTI in healthy blood donors in a tertiary care blood bank. MATERIALS AND METHODS: A retrospective study was carried out over a period of 5 years from January 2007 to December 2011...
October 2017: Journal of Laboratory Physicians
https://www.readbyqxmd.com/read/28935118/ex-vivo-trypanocidal-activity-of-1-2-hydroxybenzylidene-thiosemicarbazide-against-trypanosoma-equiperdum
#4
N Parra, M Jaume, K Boscán, A Hernández, A Mijares, M González, Y Alvarado, J Restrepo
Trypanosoma equiperdum is the causative agent of dourine, a venereal disease in horses and donkeys. This parasite has a widely distribution, is found in Africa, Asia, Southern and Eastern Europe, Russia, Mexico and Venezuela. The T. equiperdum is morphologically indistinguishable to other Trypanozoon species, however differs from other mammalian trypanosomes due to the fact that it is primarily a tissue parasite, generating cutaneous plaques, swelling of genitalia and neurological signs. The aim of this study was to evaluate the trypanocidal effectiveness of a set of derivatives of thiosemicarbazones on a T...
July 8, 2017: Veterinary Parasitology
https://www.readbyqxmd.com/read/28872683/phytochemistry-and-pharmacological-potential-of-cassia-absus-a-review
#5
REVIEW
Saeed Ahmad, Ayesha Hassan, Waheed Mumtaz Abbasi, Tayyeba Rehman
OBJECTIVES: Cassia absus is a plant of the family fabaceae with Ayurvedic ethnomedical records. It is used in traditional medicine for the treatment of bronchitis, asthma, cough, conjunctivitis, leucoderma, renal and hepatic diseases, constipation, tumors, venereal ulcer, headache, hemorrhoids and wound healing. Preliminary in vitro and in vivo studies have provided valuable scientific evidence for its use. This review aims to summarize reported pharmacognosy, traditional uses, phytochemistry and pharmacological potential of C...
September 5, 2017: Journal of Pharmacy and Pharmacology
https://www.readbyqxmd.com/read/28857363/impact-of-transmission-cycles-and-vector-competence-on-global-expansion-and-emergence-of-arboviruses
#6
REVIEW
Ankita Agarwal, Manmohan Parida, Paban Kumar Dash
Arboviruses are transmitted between arthropod vectors and vertebrate host. Arboviral infection in mosquitoes is initiated when a mosquito feeds on a viremic host. Following ingestion of a viremic blood meal by mosquitoes, virus enters midgut along with the blood, infects and replicates in midgut epithelial cells, and then escapes to the hemocoel, from where it disseminates to various secondary organs including salivary glands. Subsequently, when mosquito bites another host, a new transmission cycle is initiated...
August 30, 2017: Reviews in Medical Virology
https://www.readbyqxmd.com/read/28839405/comparative-alveolar-ridge-preservation-using-allogenous-tooth-graft-versus-free-dried-bone-allograft-a-randomized-controlled-prospective-clinical-pilot-study
#7
Chaitanya Pradeep Joshi, Cynthia Bernardo D'Lima, Urmila Chandrashekhar Samat, Prerna Ashok Karde, Agraja Ganpat Patil, Nitin Hemchandra Dani
BACKGROUND: For the first time in India, allografts from human extracted teeth were prepared. A randomized, prospective, clinicoradiographical, histological study was conducted to evaluate their efficacy in comparison with freeze-dried bone allograft (FDBA) in alveolar ridge preservation. MATERIALS AND METHODS: Graft preparation: with written consent, teeth were collected from three donors (full mouth extraction cases). Once donors' serums were tested negative for HIV, HBV, HCV, and Venereal disease research laboratory (VDRL), mineralized whole tooth allograft (WTA) and dentin allograft (DA) were prepared using the standard protocol of Tissue Bank at Tata Memorial Hospital, Mumbai, India...
April 2017: Contemporary Clinical Dentistry
https://www.readbyqxmd.com/read/28832758/risk-factors-for-syphilis-in-women-case-control-study
#8
Vilma Costa de Macêdo, Pedro Israel Cabral de Lira, Paulo Germano de Frias, Luciana Maria Delgado Romaguera, Silvana de Fátima Ferreira Caires, Ricardo Arraes de Alencar Ximenes
OBJECTIVE: To determine the sociodemographic, behavioral, and health care factors related to the occurrence of syphilis in women treated at public maternity hospitals. METHODS: This is a case-control study (239 cases and 322 controls) with women admitted to seven maternity hospitals in the municipality of Recife, Brazil, from July 2013 to July 2014. Eligible women were recruited after the result of the VDRL (Venereal Disease Research Laboratory) under any titration...
August 17, 2017: Revista de Saúde Pública
https://www.readbyqxmd.com/read/28821219/early-congenital-syphilis-recognising-symptoms-of-an-increasingly-prevalent-disease
#9
Nupur U Patel, Elias Oussedik, Erin T Landis, Lindsay C Strowd
BACKGROUND: Congenital syphilis (CS) is an infectious disease resulting from transplacental transmission of Treponema pallidum spirochetes from an infected mother to fetus during pregnancy. While uncommon, CS has shown an increased incidence in Canada and the United States since 2001 and 2012, respectively. CASE REPORT: We present the case of a 5-week-old female infant with blistering rash on the palms and soles. The infant displayed decreased movement of the left upper extremity, clinically consistent with Parrot pseudoparalysis...
August 1, 2017: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/28816862/unilateral-optic-neuritis-and-central-retinal-vasculitis-due-to-ocular-syphilis
#10
Murtaza S Khan, Dulanji K Kuruppu, Tanav A Popli, Ramana S Moorthy, Devin D Mackay
PURPOSE: Report a case of concurrent unilateral optic neuritis and central retinal artery occlusion as the presenting signs of syphilis. METHODS: A case report of a 22-year-old man with progressive unilateral vision loss. RESULTS: With no known previous history of syphilis, genital lesions, or other extraocular manifestations, the patient presented with pain with eye movements and decreased color vision. His vision dramatically worsened after a course of oral steroids...
August 14, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28792066/advances-in-the-analysis-of-less-conventional-human-body-fluids-an-overview-of-the-ce-and-hplc-ms-applications-in-the-years-2015-2017
#11
REVIEW
Monica Di Venere, Simona Viglio, Maddalena Cagnone, Anna Bardoni, Roberta Salvini, Paolo Iadarola
Aim of this article is to focus the attention of the reader on the application of CE/MS and LC/MS to the analysis of human body fluids not currently used for the diagnosis of disorders and, for this reason, catalogued as "less/nonconventional" fluids, that is, tears, nasal secretions, cerumen, bronchoalveolar lavage fluid, sputum, exhaled breath condensate, nipple aspirate, breast milk, amniotic fluid, bile, seminal plasma, liposuction aspirate fluid, and synovial fluid. The pool of articles presented in this report demonstrates that, rather than being neglected, these fluids are an important resource for the evaluation of possible pathologic conditions...
August 9, 2017: Electrophoresis
https://www.readbyqxmd.com/read/28783403/venereal-disease-in-wartime-75-years-ago
#12
Harold Ellis
No abstract text is available yet for this article.
August 2, 2017: British Journal of Hospital Medicine
https://www.readbyqxmd.com/read/28770238/functional-characterization-of-cd4-and-cd8-t-cell-responses-among-human-papillomavirus-infected-patients-with-ano-genital-warts
#13
Manjula Singh, Deepshi Thakral, Narayan Rishi, Hemanta Kumar Kar, Dipendra Kumar Mitra
Ano-genital warts are considered one of the commonest and highly infectious sexually transmitted infections. These warts are primarily caused by the human papillomavirus (HPV) of the family Papillomaviridae, genus alpha-papillomavirus, species 10 and types 6 and 11. However the high recurrence rate of warts is a matter of serious concern to the patients and a challenge for the treating physician. The conventional treatment options are targeted only to the local site of warts. There is no systemic treatment modality as there is limited understanding of the disease immune-pathogenesis...
June 2017: Virusdisease
https://www.readbyqxmd.com/read/28760477/the-society-of-thoracic-surgeons-congenital%C3%A2-heart-surgery-database-2017-update-on-research
#14
REVIEW
Marshall L Jacobs, Jeffrey P Jacobs, Kevin D Hill, Christoph Hornik, Sean M O'Brien, Sara K Pasquali, David Vener, S Ram Kumar, Robert H Habib, David M Shahian, Fred H Edwards, Felix G Fernandez
The Society of Thoracic Surgeons Congenital Heart Surgery Database (STS CHSD) is the largest congenital and pediatric cardiac surgical clinical data registry in the world. It contains data pertaining to more than 435,000 total operations. The most recent biannual feedback report to participants (Spring 2017, Report of the Twenty-Sixth Harvest) included analysis of data submitted from 127 hospitals in North America. That represents nearly all centers performing pediatric and congenital heart operations in the United States and Canada...
September 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28725623/isolation-and-characterization-of-antimicrobial-compound-from-the-stem-bark-of-the-traditionally-used-medicinal-plant-adenium-obesum
#15
Mohammed Sohail Akhtar, Mohammad Amzad Hossain, Sadri Abdullah Said
BACKGROUND: Medicinal plants constitute a natural reservoir for medicines worldwide. They serve mainstream therapeutics and are central in folklore medicine. In case of Adenium obesum (Lav, Apocynaceae), indigenous people of Oman use it for the treatment of venereal diseases, wounds, skin diseases, headaches, muscle pain as well as joint pain; yet, the active ingredients have not been classified. To screened the antioxidant and antimicrobial activities of an identified compound that we isolated from the highest active chloroform extract...
July 2017: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/28721967/sexual-behavior-of-transgenders-and-their-vulnerability-to-hiv-aids-in-an-urban-area-of-eastern-india
#16
Abhik Sinha, Dipendra Narayan Goswami, Dibakar Haldar, Sarmila Mallik, Sukamal Bisoi, Prasanta Ray Karmakar
Transgender (TG) people experience a gender identity that is different from their anatomical sex. For their high-risk sex behavior, they are important group for targeted intervention of HIV/AIDS. The objective of the study was to find the sexual behavior of TG people and to assess few aspects of their vulnerability to HIV/AIDS. This cross-sectional survey was done from June to August 2012, in field practice area of "Kosish," a nongovernmental organization run by TGs in Alipore of Kolkata metropolitan city, India...
April 2017: Indian Journal of Public Health
https://www.readbyqxmd.com/read/28682315/congenital-syphilis-in-neonates-with-nonreactive-nontreponemal-test-results
#17
P S Wozniak, J B Cantey, F Zeray, N K Leos, J S Sheffield, G D Wendel, P J Sánchez
OBJECTIVE: Infants whose mothers had syphilis during pregnancy were studied to determine how often exposed newborns with normal physical examinations and nonreactive nontreponemal serologic tests had abnormal laboratory or radiographic studies. STUDY DESIGN: Retrospective analysis of prospectively collected data from infants born to mothers with syphilis and had a normal examination and a nonreactive nontreponemal test. Some infants had IgM immunoblotting, PCR testing or rabbit infectivity testing (RIT) performed...
October 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/28660744/reconceptualizing-mental-disorders-from-symptoms-to-organs
#18
Mario Bunge
Most mental pathologies are diagnosed on the sole basis of the symptoms reported by patients, such as "I'm feeling low." The thrust of this paper is the proposal to reconceptualize mental disorders as dysfunctions of brain subsystems. This shift from symptom to organ would bring psychiatry in line with the rest of medicine, and is analogous to the change in status of venereal infections from skin pathologies, such as chancres, to bacterial infections. The proposal in question is part of the reconceptualization of mental processes as brain processes, in line with the materialist conception of the mind as neural...
June 2017: PsyCh Journal
https://www.readbyqxmd.com/read/28653418/syphilis-testing-practices-in-the-americas
#19
Thuy T Trinh, Mary L Kamb, Minh Luu, D Cal Ham, Freddy Perez
OBJECTIVE: To present the findings of the Pan American Health Organization's 2014 survey on syphilis testing policies and practices in the Americas. METHODS: Representatives of national/regional reference and large, lower-level laboratories from 35 member states were invited to participate. A semi-structured, electronically administered questionnaire collected data on syphilis tests, algorithms, equipment/commodities, challenges faced and basic quality assurance (QA) strategies employed (i...
September 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28633446/genetic-indicators-of-drug-resistance-in-the-highly-repetitive-genome-of-trichomonas-vaginalis
#20
Martina Bradic, Sally D Warring, Grace E Tooley, Paul Scheid, William E Secor, Kirkwood M Land, Po-Jung Huang, Ting-Wen Chen, Chi-Ching Lee, Petrus Tang, Steven A Sullivan, Jane M Carlton
Trichomonas vaginalis, the most common nonviral sexually transmitted parasite, causes ∼283 million trichomoniasis infections annually and is associated with pregnancy complications and increased risk of HIV-1 acquisition. The antimicrobial drug metronidazole is used for treatment, but in a fraction of clinical cases, the parasites can become resistant to this drug. We undertook sequencing of multiple clinical isolates and lab derived lines to identify genetic markers and mechanisms of metronidazole resistance...
June 1, 2017: Genome Biology and Evolution
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