Jean Bourbeau, Mohit Bhutani, Paul Hernandez, Shawn D Aaron, Marie-France Beauchesne, Sophie B Kermelly, Anthony D'Urzo, Avtar Lal, François Maltais, Jeffrey D Marciniuk, Sunita Mulpuru, Erika Penz, Don D Sin, Anne Van Dam, Joshua Wald, Brandie L Walker, Darcy D Marciniuk
Chronic obstructive pulmonary disease patient care must include confirming a diagnosis with postbronchodilator spirometry. Because of the clinical heterogeneity and the reality that airflow obstruction assessed by spirometry only partially reflects disease severity, a thorough clinical evaluation of the patient should include assessment of symptom burden and risk of exacerbations that permits the implementation of evidence-informed pharmacologic and nonpharmacologic interventions. This guideline provides recommendations from a comprehensive systematic review with a meta-analysis and expert-informed clinical remarks to optimize maintenance pharmacologic therapy for individuals with stable COPD, and a revised and practical treatment pathway based on new evidence since the 2019 update of the Canadian Thoracic Society (CTS) Guideline...
November 2023: Chest