Hiroyuki Seki, Satoshi Ideno, Toshiya Shiga, Hidenobu Watanabe, Motoaki Ono, Akira Motoyasu, Hikari Noguchi, Kazuya Kondo, Takahiro Yoshikawa, Hiroshi Hoshijima, Shunsuke Hyuga, Miho Shishii, Ai Nagai, Midoriko Higashi, Takashi Ouchi, Kazuki Yasuda, Norifumi Kuratani
Although the recommended preoperative cessation period for sodium-glucose cotransporter 2 inhibitors (SGLT2is) changed in 2020 (from 24 h to 3-4 days preoperatively) to reduce the risk of SGLT2i-associated perioperative ketoacidosis (SAPKA), the validity of the new recommendation has not been verified. Using case reports, we assessed the new recommendation effectiveness and extrapolated precipitating factors for SAPKA. We searched electronic databases up to June 1, 2022 to assess SAPKA (blood pH < 7...
February 27, 2023: Journal of Anesthesia