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https://www.readbyqxmd.com/read/29150310/zika-virus-in-french-polynesia-2013-14-anatomy-of-a-completed-outbreak
#1
REVIEW
Didier Musso, Hervé Bossin, Henri Pierre Mallet, Marianne Besnard, Julien Broult, Laure Baudouin, José Eduardo Levi, Ester C Sabino, Frederic Ghawche, Marion C Lanteri, David Baud
The Zika virus crisis exemplified the risk associated with emerging pathogens and was a reminder that preparedness for the worst-case scenario, although challenging, is needed. Herein, we review all data reported during the unexpected emergence of Zika virus in French Polynesia in late 2013. We focus on the new findings reported during this outbreak, especially the first description of severe neurological complications in adults and the retrospective description of CNS malformations in neonates, the isolation of Zika virus in semen, the potential for blood-transfusion transmission, mother-to-child transmission, and the development of new diagnostic assays...
November 14, 2017: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/29136029/a-structural-review-of-foliar-glands-in-passiflora-l-passifloraceae
#2
Renata Cristina Cassimiro de Lemos, Delmira da Costa Silva, Gladys Flavia de Albuquerque Melo-de-Pinna
Extrafloral glands in Passifloraceae species have aroused the interest of many researchers because of their wide morphological diversity. The present work analyzed the foliar glands on 34 species of Passiflora from samples containing glands in the petiole and foliar blade fixed in 50% solution of formaldehyde-ethanol-acetic acid and stored in a 70% ethanol solution. For anatomical analyses, part of the material was embedded in Paraplast, longitudinally sectioned and double stained with safranin and astra blue...
2017: PloS One
https://www.readbyqxmd.com/read/29121042/polish-translation-of-the-anatomical-quality-assurance-aqua-checklist-new-guidelines-for-reporting-in-original-anatomical-studies
#3
Brandon Michael Henry, Agata Marcinów, Przemysław Pękala, Dominik Taterra, Marios Loukas, R Shane Tubss, Jerzy A Walocha, Krzysztof A Tomaszewski
Recently, an improvement of the quality of reporting and methodology in original research has been observed. Major fields in research have introduced checklists aimed at promoting clear and univocal reporting of methods and results. The basis of evidence-based medicine (EBM) lies in transparent reporting of primary studies. Although clinical research progressed rapidly into evidence-based guidelines, the basic sciences, including anatomy, just recently started to use the rules of EBM. No anatomy-specific standardized research checklist has been introduced so far...
2017: Folia Medica Cracoviensia
https://www.readbyqxmd.com/read/29043095/applied-anatomy-today-s-requirement-for-clinical-medicine-courses
#4
Ahmad Farrokhi, Masoume Soleymaninejad, Mehrdad Ghorbanlou, Ramazan Fallah, Reza Nejatbakhsh
Anatomy as an indispensable part of the medical curricula, offering impeccable knowledge, prepares the students to enter the practical atmosphere. The aim of this study was to evaluate the clinical application of anatomy courses of the medical students in Zanjan University of Medical Sciences. This cross-sectional study was conducted in 2015 with census sampling on all clinical students (trainees and interns). To collect feedback from students, the questionnaire designed by researchers was used. The Likert rating scale of very high, high, medium, low, and very low was considered and scores of 5 (very high) to 1 (very low) were applied...
September 2017: Anatomy & Cell Biology
https://www.readbyqxmd.com/read/28962911/from-the-international-space-station-to-the-clinic-how-prolonged-unloading-may-disrupt-lumbar-spine-stability
#5
Jeannie F Bailey, Stephanie L Miller, Kristine Khieu, Conor W O'Neill, Robert M Healey, Dezba G Coughlin, Jojo V Sayson, Douglas G Chang, Alan R Hargens, Jeffrey C Lotz
Background context Prolonged microgravity exposure is associated with localized low back pain and an elevated risk of post-flight disc herniation. Though the mechanisms by which microgravity impairs the spine are unclear, they should be foundational for developing in-flight countermeasures for maintaining astronaut spine health. Because human spine anatomy has adapted to upright posture on Earth, observations of how spaceflight affects the spine should also provide new and potentially important information on spine biomechanics that benefit the general population...
September 26, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28946605/human-cadavers-to-evaluate-prototypes-of-minimally-invasive-surgical-instruments-a-feasibility-study
#6
Lukas van den Haak, Chantal Alleblas, Johann P Rhemrev, Jules Scheltes, Bertho Nieboer, Frank Willem Jansen
BACKGROUND: New technology should be extensively tested before it is tried on patients. Unfortunately representative models are lacking. In theory, fresh frozen human cadavers are excellent models. OBJECTIVE: To identify strengths and weaknesses of fresh frozen human cadavers as research models for new technology prior to implementation in gynecological surgery. METHODS: During pre-clinical validation studies regarding the MobiSep uterine manipulator, test procedures were performed on fresh frozen cadavers...
September 15, 2017: Technology and Health Care: Official Journal of the European Society for Engineering and Medicine
https://www.readbyqxmd.com/read/28925991/a-multiscale-imaging-and-modelling-dataset-of-the-human-inner-ear
#7
Nicolas Gerber, Mauricio Reyes, Livia Barazzetti, Hans Martin Kjer, Sergio Vera, Martin Stauber, Pavel Mistrik, Mario Ceresa, Nerea Mangado, Wilhelm Wimmer, Thomas Stark, Rasmus R Paulsen, Stefan Weber, Marco Caversaccio, Miguel A González Ballester
Understanding the human inner ear anatomy and its internal structures is paramount to advance hearing implant technology. While the emergence of imaging devices allowed researchers to improve understanding of intracochlear structures, the difficulties to collect appropriate data has resulted in studies conducted with few samples. To assist the cochlear research community, a large collection of human temporal bone images is being made available. This data descriptor, therefore, describes a rich set of image volumes acquired using cone beam computed tomography and micro-CT modalities, accompanied by manual delineations of the cochlea and sub-compartments, a statistical shape model encoding its anatomical variability, and data for electrode insertion and electrical simulations...
September 19, 2017: Scientific Data
https://www.readbyqxmd.com/read/28879421/the-history-of-rhoton-s-lab
#8
REVIEW
Toshio Matsushima, J Richard Lister, Ken Matsushima, Evandro de Oliveira, Erdener Timurkaynak, David A Peace, Shigeaki Kobayashi
The work performed in Dr. Rhoton's Lab, represented by over 500 publications on microneurosurgical anatomy, greatly contributed to improving the level of neurosurgical treatment throughout the world. The authors reviewed the development and activities of the Lab over 40 years. Dr. Albert L. Rhoton Jr., the founder of, and leader in, this field, displayed great creativity and ingenuity during his life. He devoted himself to perfecting his study methodology, employing high-definition photos and slides to enhance the quality of his published papers...
September 6, 2017: Neurosurgical Review
https://www.readbyqxmd.com/read/28872120/dissection-of-the-mouse-pancreas-for-histological-analysis-and-metabolic-profiling
#9
Michelle J Veite-Schmahl, Daniel P Regan, Adam C Rivers, Joseph F Nowatzke, Michael A Kennedy
We have been investigating the pancreas specific transcription factor, 1a cre-recombinase; lox-stop-lox- Kristen rat sarcoma, glycine to aspartic acid at the 12 codon (Ptf1a(cre/+);LSL-Kras(G12D/+)) mouse strain as a model of human pancreatic cancer. The goal of our current studies is to identify novel metabolic biomarkers of pancreatic cancer progression. We have performed metabolic profiling of urine, feces, blood, and pancreas tissue extracts, as well as histological analyses of the pancreas to stage the cancer progression...
August 19, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28864300/the-pregenital-abdomen-of-enicocephalomorpha-and-morphological-evidence-for-different-modes-of-communication-at-the-dawn-of-heteropteran-evolution
#10
Leonidas-Romanos Davranoglou, Petr Baňař, Christian M Schlepütz, Beth Mortimer, Graham K Taylor
The internal and external anatomy of the posterior metathoracic region, pregenital abdomen, and associated nervous system of the heteropteran infraorder Enicocephalomorpha are thoroughly described, using an array of state-of-the art techniques. Based on morphology, it is hypothesised which modes of communication these insects use. This study is based primarily on an undescribed species of Cocles Bergroth, 1905 (Enicocephalidae) and another undescribed species of Lomagostus Villiers, 1958 (Aenictopecheidae), but additional representatives of the infraorder are also examined...
September 20, 2017: Arthropod Structure & Development
https://www.readbyqxmd.com/read/28820012/effect-of-rotational-prosthetic-alignment-variation-on-tibiofemoral-contact-pressure-distribution-and-joint-kinematics-in-total-knee-replacement
#11
Xin Xie, Roy Rusly, John D DesJardins, Frank Voss, Kim Chillag, Martine LaBerge
In total knee replacement surgery, implant alignment is one of the most important criteria for successful long-term clinical outcome. During total knee replacement implantation, femoral and tibial alignment are determined through appropriate bone resections, which could vary based on patient anatomy, implant design and surgical technique and further influence loading conditions and clinical outcomes. The current research focused on three critical alignment parameters for total knee replacement insertion: femoral component internal/external (I/E) rotation, varus-valgus tibiofemoral angulation and posterior tibial slope...
August 1, 2017: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
https://www.readbyqxmd.com/read/28776670/archosauriform-endocranial-morphology-and-osteological-evidence-for-semiaquatic-sensory-adaptations-in-phytosaurs
#12
Emily J Lessner, Michelle R Stocker
The examination of endocranial data of archosauriforms has led to advances on the evolution of body size, nerve pathways, and sensory abilities. However, much of that research has focused on bird-line archosaurs, resulting in a skewed view of Archosauria. Phytosauria, a hypothesized sister taxon to or early-branching member of Archosauria, provides a potential outgroup condition. Most previous phytosaur endocranial studies were executed without the use of modern technology and focused on derived members of Phytosauria...
August 4, 2017: Journal of Anatomy
https://www.readbyqxmd.com/read/28759819/polymer-coating-embolism-from-intravascular-medical-devices-a-clinical-literature-review
#13
REVIEW
Amitabh M Chopra, Monik Mehta, Jean Bismuth, Maksim Shapiro, Michael C Fishbein, Alina G Bridges, Harry V Vinters
Over the past three decades, lubricious (hydrophobic and/or hydrophilic) polymer-coated devices have been increasingly adopted by interventional physicians and vascular surgeons to access and treat a wider range of clinical presentations. Recent clinical literature highlights the presence of polymer coating emboli within the anatomy - a result of coating separation from an intravascular device - and associates it with a range of adverse clinical sequelae. The 2015 U.S. Food and Drug Administration safety communication titled "Lubricious Coating Separation from Intravascular Medical Devices" acknowledges these concerns and concludes that it will work with stakeholders to develop nonclinical test methodologies, establish performance criteria, and identify gaps in current national and international device standards for coating integrity performance...
September 2017: Cardiovascular Pathology: the Official Journal of the Society for Cardiovascular Pathology
https://www.readbyqxmd.com/read/28749840/computed-tomography-research-relative-anatomy-of-caldwell-luc-approach-in-pterygopalatine-fossa-surgery
#14
Mei Chen Liu, Xiao Rui Yin, Yi Shui Zhang, Wen Yang, Han Wen Zhang, Hao Bo Duan, Jian Ming Liu, Kai Liang Cheng, You Qiong Li
With the development of endoscopic technique, Caldwell-Luc approach has more wide applications and becomes a common method of pterygopalatine fossa (PPF) surgery. Few data can be used in this approach to avoid injuring the vessels and nerves within this area. In this study, the authors used computed tomography to get the coordinates of inferior orbital fissure, foramen rotundum, sphenopalatine foramen, internal opening of pterygoid canal, the strangulation of PPF, and the greater palatine foramen with canine fossa as the origin...
September 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28710777/update-in-enteroscopy-new-devices-and-new-indications
#15
REVIEW
Tom G Moreels
The present review provides an update of the currently available (proto-) types of device-assisted enteroscopy (DAE). In recent years, newly designed double- and single-balloon enteroscopes have emerged. They aim to improve insertion depth into the small bowel, and they also allow more efficient endoscopic interventions. Nowadays, almost all conventional endoscopic procedures are feasible using DAE, opening the door to new indications. Recently, more data have become available on pediatric DAE, DAE-assisted colonoscopy, and DAE in patients with altered anatomy, including DAE-assisted endoscopic retrograde cholangiopancreatography and direct cholangioscopy...
July 14, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28642780/rrp42-a-subunit-of-exosome-plays-an-important-role-in-female-gametophytes-development-and-mesophyll-cell-morphogenesis-in-arabidopsis
#16
Xiaoyuan Yan, Zongyun Yan, Yuzhen Han
The exosome complex plays a central and essential role in RNA metabolism. However, current research on functions of exosome subunit in plants is limited. Here, we used an egg cell-specific promoter-controlled CRISPR/Cas9 system to knock out RRP42 which encodes a core subunit of the Arabidopsis exosome and presented evidence that RRP42 is essential for the development of female gametophytes. Next, we designed three different amiRNAs targeting RRP42. The rrp42 knock-down mutants mainly displayed variegated and serrated leaves, especially in cauline leaves...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28627007/optical-molecular-imaging-guided-radiation-therapy-part-1-integrated-x-ray-and-bioluminescence-tomography
#17
Junwei Shi, Thirupandiyur S Udayakumar, Zhiqun Wang, Nesrin Dogan, Alan Pollack, Yidong Yang
PURPOSE: X-ray CT faces challenges in differentiating tumors from surrounding healthy tissues. A bioluminescence tomography (BLT) system which can directly reconstruct the internal luminescent tumors, was developed and integrated with CT system to accurately guide radiation dose delivery. METHODS: The BLT system, employing a lens-coupled CCD camera, was physically registered with an onboard cone beam CT system in an image-guided small animal arc radiation treatment system (iSMAART)...
June 19, 2017: Medical Physics
https://www.readbyqxmd.com/read/28619402/global-health-values-of-a-multidirectional-near-peer-training-program-in-surgery-pathology-anatomy-research-methodology-and-medical-education-for-haitian-rwandan-and-canadian-medical-students
#18
Malik Elharram, Trish Dinh, Annie Lalande, Susan Ge, Sophie Gao, Geoffroy Noël
BACKGROUND: As health care delivery increasingly requires providers to cross international borders, medical students at McGill University, Canada, developed a multidirectional exchange program with Haiti and Rwanda. The program integrates surgery, pathology, anatomy, research methodology, and medical education. OBJECTIVE: The aim of the present study was to explore the global health value of this international training program to improve medical education within the environment of developing countries, such as Haiti and Rwanda, while improving sociocultural learning of Canadian students...
March 2017: Annals of Global Health
https://www.readbyqxmd.com/read/28595643/planning-strategies-for-inter-fractional-robustness-in-pancreatic-patients-treated-with-scanned-carbon-therapy
#19
Vania Batista, Daniel Richter, Stephanie E Combs, Oliver Jäkel
BACKGROUND: Managing inter-fractional anatomy changes is a challenging task in radiotherapy of pancreatic tumors, especially in scanned carbon-ion delivery. This treatment planning study aims to focus on clinically feasible solutions, such as the beam angle selection and margin design to increase the robustness against inter-fractional uncertainties. METHODS: This study included 10 patients with weekly 3D-CT imaging and physician-approved Clinical Target Volume (CTV)...
June 8, 2017: Radiation Oncology
https://www.readbyqxmd.com/read/28518066/scaled-anatomical-model-creation-of-biomedical-tomographic-imaging-data-and-associated-labels-for-subsequent-sub-surface-laser-engraving-ssle-of-glass-crystals
#20
Aislinn M Betts, Matthew T McGoldrick, Christopher R Dethlefs, Justin Piotrowicz, Tony Van Avermaete, Jeff Maki, Steve Gerstler, W M Leevy
Biomedical imaging modalities like computed tomography (CT) and magnetic resonance (MR) provide excellent platforms for collecting three-dimensional data sets of patient or specimen anatomy in clinical or preclinical settings. However, the use of a virtual, on-screen display limits the ability of these tomographic images to fully convey the anatomical information embedded within. One solution is to interface a biomedical imaging data set with 3D printing technology to generate a physical replica. Here we detail a complementary method to visualize tomographic imaging data with a hand-held model: Sub Surface Laser Engraving (SSLE) of crystal glass...
April 25, 2017: Journal of Visualized Experiments: JoVE
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