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https://www.readbyqxmd.com/read/29666994/whole-body-mri-in-spondyloarthritis-spa-preliminary-results-suggest-that-dwi-outperforms-stir-for-lesion-detection
#1
Frederic E Lecouvet, Nicolas Vander Maren, Laurence Collette, Nicolas Michoux, Perrine Triqueneaux, Maria Stoenoiu, Frederic Houssiau, Jacques Malghem, Marie-Laurence Denis, Ahmed Larbi, Adrien Nzeusseu Toukap
PURPOSE: To compare the diagnostic accuracy of DWI and STIR sequences in Whole body (WB) MRI of SpA patients. MATERIALS AND METHODS: Twenty consecutive patients with confirmed active SpA and 20 controls were investigated with identical WB MRI protocols, including DWI and STIR images. Two observers recorded 'lesions' (high signal intensity foci on STIR and high b-value DWI) in 17 anatomical areas, making a 17-point 'area score' and a 40-point 'lesion score'. ROC performance, inter-observer agreement, correlation with clinical parameters and spine and sacro-iliac joints (SIJ) MRI scores were assessed...
April 17, 2018: European Radiology
https://www.readbyqxmd.com/read/29666271/desynchronization-of-slow-oscillations-in-the-basal-ganglia-during-natural-sleep
#2
Aviv D Mizrahi-Kliger, Alexander Kaplan, Zvi Israel, Hagai Bergman
Slow oscillations of neuronal activity alternating between firing and silence are a hallmark of slow-wave sleep (SWS). These oscillations reflect the default activity present in all mammalian species, and are ubiquitous to anesthesia, brain slice preparations, and neuronal cultures. In all these cases, neuronal firing is highly synchronous within local circuits, suggesting that oscillation-synchronization coupling may be a governing principle of sleep physiology regardless of anatomical connectivity. To investigate whether this principle applies to overall brain organization, we recorded the activity of individual neurons from basal ganglia (BG) structures and the thalamocortical (TC) network over 70 full nights of natural sleep in two vervet monkeys...
April 16, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29666262/spatial-and-temporal-heterogeneity-of-neural-responses-in-human-posteromedial-cortex
#3
Amy L Daitch, Josef Parvizi
Neuroimaging evidence supports a role of the default mode network (DMN) in spontaneous thought and goal-driven internally oriented processes, such as recalling an autobiographical event, and has demonstrated its deactivation during focused, externally oriented attention. Recent work suggests that the DMN is not a homogeneous network but rather is composed of at least several subnetworks, which are engaged in distinct functions; however, it is still unclear if these different functions rely on the same neuronal populations...
April 16, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29665270/european-repository-of-explicit-criteria-of-potentially-inappropriate-medications-in-old-age
#4
Ivana Ivanova, Monique Elseviers, Maarten Wauters, Thierry Christiaens, Robert Vander Stichele
AIM: Lack of electronic assessment of medication lists in electronic health records is a barrier for more generalized use of potentially inappropriate medications (PIM) lists, designed for older adults. The aim was to construct a European repository of explicit criteria on PIM, suitable for electronic assessment. METHODS: PIM description, medication information, clinical information and level of evidence was entered. Criteria with unclear medication specifications were excluded...
April 17, 2018: Geriatrics & Gerontology International
https://www.readbyqxmd.com/read/29663720/the-40th-anniversary-of-the-congenital-anomaly-research-center-kyoto-university-graduate-school-of-medicine
#5
Shigehito Yamada, Momoko Nagai, Masatoshi Hagiwara
The Congenital Anomaly Research Center at Kyoto University's Graduate School of Medicine was established in 1975; in 2015 the center celebrated its 40th anniversary. The celebration of this anniversary included three special projects: (1) forming an achievement list, (2) preparing for a specimen exhibition, and (3) holding an anniversary symposium. This special issue of The Anatomical Record is devoting to detailing these anniversary projects. Anat Rec, 2018. © 2018 Wiley Periodicals, Inc.
April 17, 2018: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
https://www.readbyqxmd.com/read/29663092/safety-and-accuracy-of-spinal-instrumentation-surgery-in-a-hybrid-operating-room-with-an-intraoperative-cone-beam-computed-tomography
#6
Christian A Bohoun, Kentaro Naito, Toru Yamagata, Samantha Tamrakar, Kenji Ohata, Toshihiro Takami
Although spinal instrumentation technique has undergone revolutionary progress over the past few decades, it may still carry significant surgery-related risks. The purpose of the present study was to assess the radiological accuracy of spinal screw instrumentation using a hybrid operating room (OR) and quantify the related radiation exposure. This retrospective study included 33 cases of complex spine fusion surgeries that were conducted using a hybrid OR with a flat panel detector (FPD) angiography system...
April 16, 2018: Neurosurgical Review
https://www.readbyqxmd.com/read/29662914/ligament-strain-response-between-lower-extremity-contralateral-pairs-during-in-vitro-landing-simulation
#7
April L McPherson, Nathanial A Bates, Nathan D Schilaty, Christopher V Nagelli, Aaron J Krych, Timothy E Hewett
Background: Limb asymmetries, as determined through in vivo biomechanical measures, are known risk factors for anterior cruciate ligament (ACL) injury. Previous cadaveric studies have shown a lack of significant differences in ligament strain between contralateral lower extremities when identical kinematics were simulated on specimens. Recent methodological developments have applied in vivo knee kinetics to exert landing forces on cadaveric lower extremities to mimic ACL injury events, but it is unknown whether contralateral limbs fail in a consistent manner during impact simulator testing...
April 2018: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/29660745/omental-vascularized-lymph-node-flap-a-radiographic-analysis
#8
Julia A Cook, Sarah E Sasor, Sunil S Tholpady, Michael W Chu
BACKGROUND:  Vascularized lymph node transfer is an increasingly popular option for the treatment of lymphedema. The omental donor site is advantageous for its copious soft tissue, well-defined collateral circulation, and large number of available nodes, without the risk of iatrogenic lymphedema. The purpose of this study is to define the anatomy of the omental flap in the context of vascularized lymph node harvest. METHODS:  Consecutive abdominal computed tomography angiography (CTA) images performed at a single institution over a 1-year period were reviewed...
April 16, 2018: Journal of Reconstructive Microsurgery
https://www.readbyqxmd.com/read/29660156/evaluation-of-symptomatic-esophagogastric-junction-outflow-obstruction
#9
Andrew Ming Liang Ong, Vikneswaran Namasivayam, Yu Tien Wang
BACKGROUND: Esophagogastric junction outflow obstruction (EGJOO) may be due to anatomical abnormalities but it is unclear how to evaluate them after high resolution manometry (HRM). We aimed to determine 1) clinical and HRM parameters differentiating anatomical EGJOO from functional EGJOO, 2) investigations chosen and yield for anatomical EGJOO and 3) clinical outcomes of functional EGJOO. METHODS: Medical records of consecutive patients with symptomatic EGJOO from February 2012 to December 2015 were reviewed...
April 16, 2018: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29660062/minimally-invasive-exposure-of-the-maxillary-artery-at-the-anteromedial-infratemporal-fossa
#10
Roberto Rodriguez Rubio, Olivia Kola, Ali Tayebi Meybodi, Halima Tabani, Xuequan Feng, Jan-Karl Burkhardt, Sonia Yousef, Michael T Lawton, Arnau Benet
BACKGROUND: The maxillary artery (MA) has been described as a reliable donor for extracranial-intracranial high-flow bypass. Existing techniques to harvest MA require brain retraction and drilling of the middle fossa (with or without a zygomatic osteotomy), carrying the potential risks of venous bleeding, injury to the branches of the maxillary or mandibular nerves, muscular transection, or temporomandibular junction disorders. OBJECTIVE: To describe a novel technique to expose the MA without bony drilling and with minimal impact to surrounding structures...
April 12, 2018: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29659922/chronology-of-the-intrapuparial-development-of-the-blowfly-chrysomya-albiceps-diptera-calliphoridae-application-in-forensic-entomology
#11
Mônica Salazar-Souza, Márcia S Couri, Valeria M Aguiar
Insects display different patterns of development, and blow flies have one of the most specialized patterns of intrapuparial development of all. In forensic entomology, pupae can be used as a tool to estimate the minimum postmortem time interval (minPMI). We analyzed the intrapuparial development of Chrysomya albiceps (Diptera: Caloricidade), whose larvae had been fed pig lungs and reared in a climate-controlled room at 28°C day/26°C night, 70 ± 10% RH, and 12 h of photophase and monitored daily. After the third-instar larvae abandoned their diet, the process of pupariation and pupation was monitored...
April 12, 2018: Journal of Medical Entomology
https://www.readbyqxmd.com/read/29659312/anatomical-distribution-of-musculoskeletal-disorders-following-a-road-traffic-collision-in-litigants-presenting-to-physiotherapists-within-a-private-clinic-in-north-east-england
#12
Jennifer Sewell, Cheryl Dixon, Rosie Morris, Samuel Stuart
INTRODUCTION: Musculoskeletal disorders (MSDs) are common following a road traffic collision (RTC) in England. Establishing the anatomical distribution of MSDs following RTC that present to physiotherapists may improve understanding and clinical practice. This study examined anatomical distribution of MSDs that present to physiotherapists within a litigant population following a RTC in England. METHODS: A retrospective review of physiotherapy records was conducted at a private practice in North-East England...
April 16, 2018: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/29658820/umbilical-microbiome-and-laparoscopic-surgery-a-descriptive-clinical-study
#13
Alberto Aiolfi, Emanuele Asti, Elena Costa, Davide Ferrari, Gianluca Bonitta, Paola Gaia, Milvana Tedaja, Luigi Bonavina
BACKGROUND: The human skin microbiome consists of colonizing and pathogen germs. The umbilical dimple is a humid environment prone to bacterial colonization and growth. In the laparoscopic era, the umbilicus has become the most common site of entrance into the peritoneum. The aim of this study was to describe the characteristics of umbilical microflora before antiseptic skin preparation. METHODS: Descriptive single-center study. A series of patients who underwent laparoscopic/open and elective/urgent abdominal surgery over a 2-month period were included...
April 16, 2018: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/29658389/comparison-of-endoscopic-assisted-and-temporary-keratoprosthesis-assisted-vitrectomy-in-combat-ocular-trauma-experience-at-a-tertiary-eye-center-in-turkey
#14
Onder Ayyildiz, Ali Hakan Durukan
Objective This study was performed to compare the functional and anatomical results of endoscopic-assisted and temporary keratoprosthesis (TKP)-assisted vitrectomy in patients with combat ocular trauma (COT). Methods The medical records of 14 severely injured eyes of 12 patients who underwent endoscopy or TKP implantation in combination with vitreoretinal surgery from 2007 to 2015 were retrospectively evaluated. The patients' ocular history and functional and anatomic anterior and posterior segment results were analyzed...
January 1, 2018: Journal of International Medical Research
https://www.readbyqxmd.com/read/29657115/novelty-sensitive-dopaminergic-neurons-in-the-human-substantia-nigra-predict-success-of-declarative-memory-formation
#15
Jan Kamiński, Adam N Mamelak, Kurtis Birch, Clayton P Mosher, Michele Tagliati, Ueli Rutishauser
The encoding of information into long-term declarative memory is facilitated by dopamine. This process depends on hippocampal novelty signals, but it remains unknown how midbrain dopaminergic neurons are modulated by declarative-memory-based information. We recorded individual substantia nigra (SN) neurons and cortical field potentials in human patients performing a recognition memory task. We found that 25% of SN neurons were modulated by stimulus novelty. Extracellular waveform shape and anatomical location indicated that these memory-selective neurons were putatively dopaminergic...
April 7, 2018: Current Biology: CB
https://www.readbyqxmd.com/read/29656611/modified-breath-hold-compressed-sensing-3d-mr-cholangiopancreatography-with-a-small-field-of-view-and-high-resolution-acquisition-clinical-feasibility-in-biliary-and-pancreatic-disorders
#16
Liang Zhu, Huadan Xue, Zhaoyong Sun, Tianyi Qian, Elisabeth Weiland, Bernd Kuehn, Patrick Asbach, Bernd Hamm, Zhengyu Jin
BACKGROUND: Compressed-sensing (CS) accelerated 3D MR cholangiopancreatography (MRCP) could be acquired in both navigator-triggered (NT) and breath-hold (BH) mode, but the latter has been considered inferior in depicting pancreatic duct and diagnosing pancreatic duct-related diseases. PURPOSE: To prospectively evaluate the clinical feasibility of a modified 3D BH-CS-MRCP prototype protocol with small field-of-view (FOV) and higher spatial resolution, and to compare its performance to the original BH-CS-MRCP and NT-CS-MRCP...
April 14, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/29653251/probabilistic-guidance-for-catheter-tip-motion-in-cardiac-ablation-procedures
#17
Mihaela Am Constantinescu, Su-Lin Lee, Sabine Ernst, Apit Hemakom, Danilo Mandic, Guang-Zhong Yang
Radiofrequency catheter ablation is one of the commonly available therapeutic methods for patients suffering from cardiac arrhythmias. The prerequisite of successful ablation is sufficient energy delivery at the target site. However, cardiac and respiratory motion, coupled with endocardial irregularities, can cause catheter drift and dispersion of the radiofrequency energy, thus prolonging procedure time, damaging adjacent tissue, and leading to electrical reconnection of temporarily ablated regions. Therefore, positional accuracy and stability of the catheter tip during energy delivery is of great importance for the outcome of the procedure...
March 23, 2018: Medical Image Analysis
https://www.readbyqxmd.com/read/29653151/selective-decline-in-the-prevalence-of-slowly-adapting-type-i-mechanoreceptors-during-development
#18
Peter M B Cahusac, Solomon Senok
Merkel nerve endings are identified physiologically as slowly adapting type I mechanoreceptor units. They are important for fine acuity tactile perception. We examined the effect of age on the electrophysiological availability of different types of slowly adapting mechanoreceptor units. Using 6 - 50 week old rats, we observed an obvious decline with age in the probability of recording from St I units of the deep vibrissal nerve. The precipitous decline occurred between ages 6 - 14 weeks and then stabilized...
April 10, 2018: International Journal of Developmental Neuroscience
https://www.readbyqxmd.com/read/29652243/dorsal-rhizotomy-for-children-with-spastic-diplegia-of-cerebral-palsy-origin-usefulness-of-intraoperative-monitoring
#19
George Georgoulis, Andrei Brînzeu, Marc Sindou
OBJECTIVE The utility of intraoperative neuromonitoring (ION), namely the study of muscle responses to radicular stimulation, remains controversial. The authors performed a prospective study combining ventral root (VR) stimulation for mapping anatomical levels and dorsal root (DR) stimulation as physiological testing of metameric excitability. The purpose was to evaluate to what extent the intraoperative data led to modifications in the initial decisions for surgical sectioning established by the pediatric multidisciplinary team (i...
April 13, 2018: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/29652176/medication-use-in-women-and-men-with-sudden-unexpected-death
#20
Sonalie Patel, Mitchell M Conover, Golsa Joodi, Sarah Chen, Ross J Simpson, Zachariah M Deyo
BACKGROUND: In Wake County, NC, sudden unexpected death accounts for 10% to 15% of all natural deaths in individuals 18 to 64 years old. Medications such as aspirin, angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, statins, and β-blockers are recommended in guidelines to reduce cardiovascular events and even sudden death (β-blockers). However, guidelines are often underpracticed, even in high-risk patients, with noted disparities in women. OBJECTIVE: We assessed the relation between prescription of evidence-based medications and sudden unexpected death in Wake County, NC...
April 1, 2018: Annals of Pharmacotherapy
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