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https://www.readbyqxmd.com/read/28823144/factors-impacting-patient-cooperation-during-elective-gastroscopy
#1
Sang Pyo Lee, In-Kyung Sung, Jeong Hwan Kim, Sun-Young Lee, Hyung Seok Park, Chan Sup Shim
Background/Aims: Some people have difficulty tolerating upper endoscopy. The cause of and risk factors for this are not well known. The aim of this study was to investigate the factors involved in poor cooperation during screening upper endoscopy. Methods: A total of 4,422 subjects who underwent a health inspection with upper endoscopy carried out by a single experienced endoscopist were included. We retrospectively investigated subjects' self-reporting questionnaires and medical records, including endoscopic and histologic findings...
August 22, 2017: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/28823039/hydroponic-screening-of-fast-growing-tree-species-for-lead-phytoremediation-potential
#2
Jiraporn Yongpisanphop, Sandhya Babel, Maleeya Kruatrachue, Prayad Pokethitiyook
Using trees as phytoremediators has become a powerful tool to remediate lead from contaminated environments. This study aims to identify potential candidates among fast-growing trees by comparing their ability to tolerate and accumulate Pb. Cuttings from Acacia mangium, Azadirachta indica, Eucalyptus camaldulensis, and Senna siamea were cultured in 25% modified Hoagland's solutions supplemented with 10, 30, and 50 mg/L Pb for 15 days. Lead concentrations were determined by a flame atomic absorption spectrophotometer...
August 20, 2017: Bulletin of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/28822969/preconditioning-with-the-bkca-channel-activator-ns-1619-prevents-ischemia-reperfusion-induced-inflammation-and-mucosal-barrier-dysfunction-ros-and-ho-1
#3
Hongyan Dai, Meifang Wang, Parag N Patel, Theodore J Kalogeris, Yajun Liu, William Durante, Ronald J Korthuis
Activation of large conductance, calcium-activated potassium (BKCa) channels evokes cell survival programs that mitigate intestinal ischemia and reperfusion (I/R) inflammation and injury 24 hours later. The goal of the current study was to determine the role of reactive oxygen species (ROS) and heme oxygenase (HO)-1 in delayed acquisition of tolerance to I/R induced by pretreatment with the BKCa channel opener NS-1619. Superior mesentery arteries were occluded for 45 min followed by reperfusion for 70 min in wild type (WT) or HO-1 null (HO-1(-/-)) mice that were pretreated with NS-1619 or saline vehicle 24 hrs earlier...
August 19, 2017: American Journal of Physiology. Heart and Circulatory Physiology
https://www.readbyqxmd.com/read/28822946/differential-expression-of-vacuolar-and-defective-cell-wall-invertase-genes-in-roots-and-seeds-of-metalliferous-and-non-metalliferous-populations-of-rumex-dentatus-under-copper-stress
#4
Zhong-Rui Xu, Shen-Wen Cai, Wu-Xing Huang, Rong-Xiang Liu, Zhi-Ting Xiong
Acid invertase activities in roots and young seeds of a metalliferous population (MP) of Rumex dentatus were previously observed to be significantly higher than those of a non-metalliferous population (NMP) under Cu stress. To date, no acid invertase gene has been cloned from R. dentatus. Here, we isolated four full-length cDNAs from the two populations of R. dentatus, presumably encoding cell wall (RdnCIN1 and RdmCIN1 from the NMP and MP, respectively) and vacuolar invertases (RdnVIN1 and RdmVIN1 from the NMP and MP, respectively)...
August 17, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28822895/gut-microbiota-trajectory-in-patients-with-severe-burn-a-time-series-study
#5
Xinying Wang, Jianbo Yang, Feng Tian, Li Zhang, Qiucheng Lei, Tingting Jiang, Jihong Zhou, Siming Yuan, Jun Wang, Zhijian Feng, Jieshou Li
PURPOSE: This time series experiments aimed to investigate the dynamic change of gut microbiomes after severe burn and its association with enteral nutrition (EN). MATERIALS AND METHODS: Seven severely burned patients who suffered from a severe metal dust explosion injury were recruited in this study. The dynamic changes of gut microbiome of fecal samples at six time points (1-3days, 2, 3, 4, 5 and 6weeks after severe burn) were detected using 16S ribosomal RNA pyrosequencing technology...
August 12, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/28822892/angiolymphoid-hyperplasia-with-eosinophilia-involving-the-common-digital-artery-of-the-hand-a-case-report-and-classification-of-upper-limb-lesions
#6
Mohammad M Al-Qattan, Maha Arafah, Felwa Al-Marshad
INTRODUCTION: Angiolymphoid hyperplasia with eosinophilia (ALHE) is a rare benign reactive inflammatory lesion. The usual presentation is a single or multiple skin nodules of the head and neck. Involvement of the hand is very rare and there have been no comprehensive reviews on ALHE of the upper limb. In this paper, we report on a case involving the common digital artery of the hand. We also review the literature and offer two classification systems for upper limb lesions: One according to the primary structure involved, and the other according to the presentation with either single or multiple lesions...
August 10, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28822810/post-stress-metabolic-trajectories-in-young-and-old-flies
#7
Hervé Colinet, David Renault
Hallmarks of aging and age-related mortality (actuarial senescence) have received major focus in the published literature, while fewer studies have investigated functional senescence. Age-related decline in the performance of organism is particularly important for organisms exposed to environmental stress, as the range of conditions allowing physiological equilibria narrows with age (homeostenosis concept). During aging, compensatory metabolic responses might occur to maintain the redox potential and homeostasis...
August 16, 2017: Experimental Gerontology
https://www.readbyqxmd.com/read/28822619/experiential-documentation-of-trimad-for-its-anti-obesity-potential-a%C3%A2-survey-of-ayurvedic-physicians-from-pune-city
#8
Megha Salunke, Manasi Deshpande, Supriya Bhalerao
BACKGROUND: Trimad is an Ayurvedic polyherbal formulation consisting of tubers of Mustaka (Cyperus rotundus), fruits of Vidanga (Embelia ribes) and roots of Chitraka (Plumbago zeylanica). It is recommended in Ayurveda for the management of obesity. However, there is no documented evidence about its safety and efficacy. Hence, as a first step, we carried out a survey to find out its usage by Ayurvedic physicians and their personal clinical experiences while using the formulation. METHODOLOGY: A questionnaire was designed which included questions regarding the usage, dosage, formulation, safety and tolerability of Trimad...
August 16, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/28822514/anthropometric-indicators-as-predictor-of-pre-diabetes-in-indian-adolescents
#9
Umeshwar Pandey, Tanu Midha, Yashwant Kumar Rao, Pravin Katiyar, Pranay Wal, Samarjeet Kaur, Dinesh Singh Martolia
INTRODUCTION: In India, there are approximately 41 million diabetics to date. Impaired glucose tolerance or pre-diabetes may occur as early as adolescence. OBJECTIVE: To find out the cut-off values of body mass index (BMI) and waist circumference to predict pre-diabetes in adolescents in north India. METHODS: A cross-sectional study was conducted among 526 students aged 17-19 years, in the Institute of Paramedical Sciences, Chatrapati Shahuji Maharaj University, Kanpur...
July 2017: Indian Heart Journal
https://www.readbyqxmd.com/read/28822486/adaptation-to-toxic-hosts-as-a-factor-in-the-evolution-of-insecticide-resistance
#10
REVIEW
Andrei Alyokhin, Yolanda H Chen
Insecticide resistance is a serious economic problem that jeopardizes sustainability of chemical control of herbivorous insects and related arthropods. It can be viewed as a specific case of adaptation to toxic chemicals, which has been driven in large part, but not exclusively, by the necessity for insect pests to tolerate defensive compounds produced by their host plants. Synthetic insecticides may simply change expression of specific sets of detoxification genes that have evolved due to ancestral associations with host plants...
June 2017: Current Opinion in Insect Science
https://www.readbyqxmd.com/read/28822339/effects-of-simulated-n-deposition-on-foliar-nutrient-status-n-metabolism-and-photosynthetic-capacity-of-three-dominant-understory-plant-species-in-a-mature-tropical-forest
#11
Qinggong Mao, Xiankai Lu, Hui Mo, Per Gundersen, Jiangming Mo
Anthropogenic increase of nitrogen (N) deposition has threatened forest ecosystem health at both regional and global scales. In N-limited ecosystems, atmospheric N input is regarded as an important nutrient source for plant growth. However, it remains an open question on how elevated N deposition affects plant growth in N-rich forest ecosystems. To address this question, we used a simulated N deposition experiment in an N-rich mature tropical forest of southern China, with N addition levels as 0kgNha(-1)yr(-1) (Control), 50kgNha(-1)yr(-1) (Low-N), 100kgNha(-1)yr(-1) (Middle-N) and 150kgNha(-1)yr(-1) (High-N), respectively...
August 16, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28822254/a-systematic-review-of-hypertension-outcomes-and-treatment-strategies-in-older-adults
#12
REVIEW
Julienne K Kirk, Julie Allsbrook, Maggie Hansell, Emily M Mann
OBJECTIVE: To evaluate the literature regarding blood pressure control and management in older adult patient population over 70 years of age. METHODS: A literature search was conducted using PubMed and capturing the data from 2006 to 2016. Terms used included MeSH headings for hypertension/therapy and antihypertension agents. A systematic review of published studies was performed. Articles including older patients (average age 70 years or older) being treated for hypertension were included...
July 25, 2017: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/28822091/effect-of-ap102-a-subtype-2-and-5-specific-somatostatin-analog-on-glucose-metabolism-in-rats
#13
Erika Tarasco, Petra Seebeck, Svende Pfundstein, Adrian F Daly, Philippe J Eugster, Alan G Harris, Eric Grouzmann, Thomas A Lutz, Christina N Boyle
PURPOSE: Somatostatin analogs are widely used to treat conditions associated with hormonal hypersecretion such as acromegaly and metastatic neuroendocrine tumors. First generation somatostatin analogs, such as octreotide and lanreotide, have high affinity for somatostatin receptor subtype 2 (SSTR2), but have incomplete efficacy in many patients. Pasireotide targets multiple SSTRs, having the highest affinity for SSTR5, but causes hyperglycemia and diabetes mellitus in preclinical and clinical studies...
August 18, 2017: Endocrine
https://www.readbyqxmd.com/read/28821952/genome-wide-association-study-and-gene-set-analysis-for-understanding-candidate-genes-involved-in-salt-tolerance-at-the-rice-seedling-stage
#14
Jie Yu, Weiguo Zao, Qiang He, Tae-Sung Kim, Yong-Jin Park
Salt is the major factor limiting crop productivity in saline soils and is controlled by various genes. The development of salt-tolerant rice through molecular breeding methods is important to meet the needs of rice breeding. We used 295 accessions to perform a genome-wide association study (GWAS) of salt tolerance-related phenotypes in rice at the seedling stage and obtained 93 candidate genes with high association peaks across six phenotypes. We constructed a protein interaction network using the candidate genes identified here, and 33 genes were associated...
August 18, 2017: Molecular Genetics and Genomics: MGG
https://www.readbyqxmd.com/read/28821885/the-expression-profiles-of-mirna-mrna-of-early-response-in-genetically-improved-farmed-tilapia-oreochromis-niloticus-liver-by-acute-heat-stress
#15
Jun Qiang, Wen J Bao, Fan Y Tao, Jie He, Xia H Li, Pao Xu, Lan Y Sun
Genetically improved farmed tilapia (GIFT, Oreochromis niloticus) are commercially important fish that are cultured in China. GIFT are highly susceptible to diseases when exposed to high temperatures in summer. Better understanding the GIFT regulatory response to heat stress will not only help in determining the relationship between heat stress signalling pathways and adaption mechanisms, but will also contribute to breeding new high-temperature tolerant strains of GIFT. In this study, we built control (28 °C) and heat-treated (37...
August 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28821876/transcriptomic-biochemical-and-physio-anatomical-investigations-shed-more-light-on-responses-to-drought-stress-in-two-contrasting-sesame-genotypes
#16
Komivi Dossa, Donghua Li, Linhai Wang, Xiaomin Zheng, Aili Liu, Jingyin Yu, Xin Wei, Rong Zhou, Daniel Fonceka, Diaga Diouf, Boshou Liao, Ndiaga Cissé, Xiurong Zhang
Sesame is an important oilseed crop with a high oil quality. It is prone to drought stress in the arid and semi-arid areas where it is widely grown. This study aims to decipher the response of tolerant (DT) and sensitive (DS) genotypes to progressive drought based on transcriptome, biochemical and physio-anatomical characterizations. Results indicated that under severe stress, DT relied on a well-functioning taproot while DS displayed a disintegrated root due to collapsed cortical cells. This was attributed to a higher accumulation of osmoprotectants and strong activity of antioxidant enzymes especially peroxidases in DT...
August 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28821860/gaba-accretion-reduces-lsi-1-and-lsi-2-gene-expressions-and-modulates-physiological-responses-in-oryza-sativa-to-provide-tolerance-towards-arsenic
#17
Navin Kumar, Arvind Kumar Dubey, Atul Kumar Upadhyay, Ambedkar Gautam, Ruma Ranjan, Saripella Srikishna, Nayan Sahu, Soumit Kumar Behera, Shekhar Mallick
GABA counteracts wide range of stresses through regulation of GABA shunt pathway in plants. Although, GABA assisted tolerance against As toxicity in plants is still unexplored. We have examined GABA induced tolerance in rice seedlings with two exposure periods of GABA i.e., short term and long term. Results showed that accumulation of GABA reduced the expressions of Lsi-1 and Lsi-2 transporter genes, which ultimately decreased the accumulation of As in rice seedlings. The accumulation of GABA also modulated the gene expression of GABA shunt pathway and activity of antioxidant enzymes, which strongly induced the tolerance in plants...
August 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28821804/nos2-deficient-mice-with-hypoxic-necrotizing-lung-lesions-predict-outcomes-of-tuberculosis-chemotherapy-in-humans
#18
Martin Gengenbacher, Maria A Duque-Correa, Peggy Kaiser, Stefanie Schuerer, Doris Lazar, Ulrike Zedler, Stephen T Reece, Amit Nayyar, Stewart T Cole, Vadim Makarov, Clifton E Barry Iii, Véronique Dartois, Stefan H E Kaufmann
During active TB in humans a spectrum of pulmonary granulomas with central necrosis and hypoxia exists. BALB/c mice, predominantly used in TB drug development, do not reproduce this complex pathology thereby inaccurately predicting clinical outcome. We found that Nos2 (-/-) mice incapable of NO-production in immune cells as microbial defence uniformly develop hypoxic necrotizing lung lesions, widely observed in human TB. To study the impact of hypoxic necrosis on the efficacy of antimycobacterials and drug candidates, we subjected Nos2 (-/-) mice with TB to monotherapy before or after establishment of human-like pathology...
August 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28821801/experimental-study-of-rheological-properties-and-oil-displacement-efficiency-in-oilfields-for-a-synthetic-hydrophobically-modified-polymer
#19
Pengcheng Liu, Zhenbao Mu, Chao Wang, Yanling Wang
In a previous study, we developed a synthetic hydrophobically modified hydroxyethyl cellulose (HEC) using bromododecane (BD), which we denote as BD-HMHEC. In this work, we continually investigate the rheological properties and its oil displacement efficiency in PuTao well area in Daqing oilfields, China. Results show that BD-HMHEC solution has good viscosification, thermal-resistance, salt-tolerance, shear resistance, and acid/alkali resistance. The storage modulus (G') and the loose modulus (G") of the BD-HMHEC solutions increase significantly with increasing BD-HMHEC concentration, and the solution becomes viscoelastic at a sufficiently high BD-HMHEC concentration...
August 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28821771/thermal-acclimation-mitigates-cold-induced-paracellular-leak-from-the-drosophila-gut
#20
Heath A MacMillan, Gil Y Yerushalmi, Sima Jonusaite, Scott P Kelly, Andrew Donini
Chill susceptible insects suffer tissue damage and die at low temperatures. The mechanisms that cause chilling injury are not well understood but a growing body of evidence suggests that a cold-induced loss of ion and water homeostasis leads to hemolymph hyperkalemia that depolarizes cells, leading to cell death. The apparent root of this cascade is the net leak of osmolytes down their concentration gradients in the cold. Many insects, however, are capable of adjusting their thermal physiology, and cold-acclimated Drosophila can maintain homeostasis and avoid injury better than warm-acclimated flies...
August 18, 2017: Scientific Reports
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