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https://www.readbyqxmd.com/read/28210099/study-of-polymorphisms-in-the-tp53-and-rb1-genes-in-children-with-retinoblastoma-in-northern-mexico
#1
Edwin J Anaya-Pava, Jesús Nares-Cisneros, Rubén I Cárdenas-Hernández, Yolanda Jaramillo-Rodríguez, Graciela Zambrano-Galván
PURPOSE: To determine the frequency and association of polymorphisms in the TP53 and RB1 genes with clinical characteristics in a group of children with retinoblastoma (RB) in northern Mexico. METHODS: A prospective, longitudinal, and analytical study of 11 patients diagnosed with RB was conducted. Endpoint PCR and high-resolution real-time PCR were performed. Chi-square and Student t tests were used to evaluate associations between variables. Allelic frequencies, as well as genotypic and Hardy-Weinberg equilibriums, were evaluated using Guo and Thompson's method...
2017: Molecular Vision
https://www.readbyqxmd.com/read/28209173/moving-from-legality-to-reality-how-medical-abortion-methods-were-introduced-with-implementation-science-in-zambia
#2
Tamara Fetters, Ghazaleh Samandari, Patrick Djemo, Bellington Vwallika, Stephen Mupeta
BACKGROUND: Although abortion is technically legal in Zambia, the reality is far more complicated. This study describes the process and results of galvanizing access to medical abortion where abortion has been legal for many years, but provision severely limited. It highlights the challenges and successes of scaling up abortion care using implementation science to document 2 years of implementation. METHODS: An intervention between the Ministry of Health, University Teaching Hospital and the international organization Ipas, was established to introduce medical abortion and to address the lack of understanding and implementation of the country's abortion law...
February 16, 2017: Reproductive Health
https://www.readbyqxmd.com/read/28201747/how-chlamydomonas-handles-nitrate-and-the-nitric-oxide-cycle
#3
Victoria Calatrava, Alejandro Chamizo-Ampudia, Emanuel Sanz-Luque, Francisco Ocaña-Calahorro, Angel Llamas, Emilio Fernandez, Aurora Galvan
No abstract text is available yet for this article.
February 12, 2017: Journal of Experimental Botany
https://www.readbyqxmd.com/read/28198144/the-phenolic-fraction-of-extra-virgin-olive-oil-modulates-the-activation-and-the-inflammatory-response-of-t-cells-from-patients-with-systemic-lupus-erythematosus-and-healthy-donors
#4
Marina Aparicio-Soto, Marina Sanchez-Hidalgo, Ana Cárdeno Galván, Jose Manuel Lucena, Francisca Gonzalez-Escribano, Maria Jesus Castillo Palma, Catalina Alarcón-de-la-Lastra
SCOPE: Systemic lupus erythematosus (SLE) is a chronic multiorgan autoimmune disease characterized by immune deregulation, which involves altered T-cell response and imbalance of cytokine production. The phenolic fraction (PE) of extra virgin olive oil (EVOO) possesses anti-inflammatory and immunomodulatory properties and exerts preventive effects in murine models of immune-inflammatory diseases, such as SLE. The present study was designed to determine the in vitro effects of the PE from EVOO on peripheral blood mononuclear cells (PBMC) from inactive patients with SLE and healthy donors...
February 15, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28195990/improvements-in-health-related-quality-of-life-cardio-metabolic-health-and-fitness-in-postmenopausal-women-after-a-supervised-multicomponent-adapted-exercise-program-in-a-suited-health-promotion-intervention-a-multigroup-study
#5
Débora Godoy-Izquierdo, Nicolás Mendoza Ladrón de Guevara, Mercedes Vélez Toral, Carlos de Teresa Galván, Alberto Salamanca Ballesteros, Juan F Godoy García
OBJECTIVES: This study explored the multidimensional outcomes that resulted from the adherence to regular exercise among previously sedentary postmenopausal women. The exercise was managed through a supervised, multicomponent, adapted approximately 20-week program in a suited health promotion intervention. METHODS: A multigroup, mixed-design study with between-group (intervention, sedentary, and active women) and within-subject measures (baseline, postintervention, and 3- and 12-month follow-ups) was conducted using intention-to-treat methodology...
February 13, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28195692/size-controlled-pd-nanoparticle-catalysts-prepared-by-galvanic-displacement-into-a-porous-si-iron-oxide-nanoparticle-host
#6
Taeho Kim, Xin Fu, David Warther, Michael J Sailor
Porous silicon nanoparticles containing both Pd and iron oxide nanoparticles are prepared and studied as magnetically recoverable catalysts for organic reductions. The Pd nanoparticles are generated in situ by electroless deposition of Pd(NH3)4(2+), where the porous Si skeleton acts as both a template and as a reducing agent and the released ammonia ligands raise the local pH to exert control over the size of the Pd nanoparticles. The nanocomposites are characterized by transmission electron microscopy (TEM), energy-dispersive X-ray spectroscopy (EDS), nitrogen adsorption, X-ray diffraction (XRD), superconducting quantum interference device (SQUID) magnetization, and dynamic light scattering (DLS)...
February 14, 2017: ACS Nano
https://www.readbyqxmd.com/read/28192673/the-benefit-of-a-supplement-with-the-antioxidant-melatonin-on-redox-status-and-muscle-damage-in-resistance-trained-athletes
#7
Roberto C Leonardo-Mendonça, Javier Ocaña-Wilhelmi, Tomás de Haro, Carlos de Teresa-Galván, Eduardo Guerra-Hernández, Iryna Rusanova, Marisol Fernández-Ortiz, Ramy Ka Sayed, Germaine Escames, Darío Acuña-Castroviejo
Previous data showed that the administration of high doses of melatonin improved the circadian system in athletes. Here, we investigated in the same experimental paradigm whether the antioxidant properties of melatonin has also beneficial effects against exercise-induced oxidative stress and muscle damage in athletes. Twenty-four athletes were treated with 100 mg.day-1 of melatonin or placebo 30 min before bedtime during four weeks in a randomized double-blind scheme. Exercise intensity was higher during the study that before starting it...
February 13, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/28192038/corrigendum
#8
(no author information available yet)
Original article: Cohen, A. O., Breiner, K., Steinberg, L., Bonnie, R. J., Scott, E. S., Taylor-Thompson, K. A., Rudolf, M. D., Chein, J., Richeson, J. A., Heller, A. S., Silverman, M. R., Dellarco, D. V., Fair, D. A., Galván, A., & Casey, B. J. (2016). When is an adolescent an adult? Assessing cognitive control in emotional and nonemotional contexts. Psychological Science, 27, 549-562. doi: 10.1177/0956797615627625.
February 1, 2017: Psychological Science
https://www.readbyqxmd.com/read/28191960/new-nanoconfined-galvanic-replacement-synthesis-of-hollow-sb-c-yolk-shell-spheres-constituting-a-stable-anode-for-high-rate-li-na-ion-batteries
#9
Yan Yu, Jun Liu, Litao Yu, Chao Wu, Yuren Wen, Kuibo Yin, Fu-Kuo Chiang, Renzong Hu, Jiangwen Liu, Litao Sun, Lin Gu, Joachim Maier, Min Zhu
In the current research project, we have designed and fabricated a biomimetic yolk-shell structure Sb@C anode for both Li- and Na-ion batteries via a nanoconfined galvanic replacement route. The yolk-shell microstructure consists of Sb hollow yolk completely protected by a self-supporting carbon thin shell. The substantial void space in the hollow yolk and the gap between the shell and inner yolk allows for the full expansion of inner Sb nanoparticles while preserving the structural integrity of the Sb@C anode and stable SEI film on the outside carbon surface...
February 13, 2017: Nano Letters
https://www.readbyqxmd.com/read/28190887/alma-compact-array-observations-of-the-fried-egg-nebula-evidence-for-large-scale-asymmetric-mass-loss-from-the-yellow-hypergiant-iras-17163-3907
#10
S H J Wallström, E Lagadec, S Muller, J H Black, N L J Cox, R Galván-Madrid, K Justtanont, S Longmore, H Olofsson, R D Oudmaijer, G Quintana-Lacaci, R Szczerba, W Vlemmings, H van Winckel, A Zijlstra
Yellow hypergiants are rare and represent a fast evolutionary stage of massive evolved stars. That evolutionary phase is characterised by a very intense mass loss, the understanding of which is still very limited. Here we report ALMA Compact Array observations of a 50″-mosaic toward the Fried Egg nebula, around one of the few Galactic yellow hypergiants IRAS 17163-3907. The emission from the (12)CO J=2-1 line, H30α recombination line, and continuum is imaged at a resolution of ~8″, revealing the morphology of the molecular environment around the star...
January 10, 2017: Astronomy and Astrophysics
https://www.readbyqxmd.com/read/28183655/differential-cytotoxicity-and-internalization-of-graphene-family-nanomaterials-in-myocardial-cells
#11
Flavio F Contreras-Torres, Andrés Rodríguez-Galván, Carlos E Guerrero-Beltrán, Erick Martínez-Lorán, Eduardo Vázquez-Garza, Nancy Ornelas-Soto, Gerardo García-Rivas
Given the well-known physical properties of graphene oxide (GO), numerous applications for this novel nanomaterial have been recently envisioned to improve the performance of biomedical devices. However, the toxicological assessment of GO, which strongly depends on the used material and the studied cell line, is a fundamental task that needs to be performed prior to its use in biomedical applications. Therefore, the toxicological characterization of GO is still ongoing. This study contributes to this, aiming to synthesize and characterize GO particles and thus investigate their toxic effects in myocardial cells...
April 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28181565/genetic-susceptibility-variants-for-lung-cancer-replication-study-and-assessment-as-expression-quantitative-trait-loci
#12
Giulia Pintarelli, Chiara Elisabetta Cotroneo, Sara Noci, Matteo Dugo, Antonella Galvan, Simona Delli Carpini, Lorena Citterio, Paolo Manunta, Matteo Incarbone, Davide Tosi, Luigi Santambrogio, Tommaso A Dragani, Francesca Colombo
Many single nucleotide polymorphisms (SNPs) have been associated with lung cancer but lack confirmation and functional characterization. We retested the association of 56 candidate SNPs with lung adenocarcinoma risk and overall survival in a cohort of 823 Italian patients and 779 healthy controls, and assessed their function as expression quantitative trait loci (eQTLs). In the replication study, eight SNPs (rs401681, rs3019885, rs732765, rs2568494, rs16969968, rs6495309, rs11634351, and rs4105144) associated with lung adenocarcinoma risk and three (rs9557635, rs4105144, and rs735482) associated with survival...
February 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28180984/beyond-a-moral-obligation-a-legal-framework-for-emergency-and-essential-surgical-care-and-anesthesia
#13
Kashmira S Chawla, Lainie Rutkow, Kent Garber, Adam L Kushner, Barclay T Stewart
BACKGROUND: Access to quality and timely emergency and essential surgical care and anesthesia (EESCA) is an integral component of the right to health as reinforced by the ratification of the World Health Assembly Resolution 68.15. However, this resolution is merely a guideline and has not been able to bolster the necessary political will to promote EESCA. Our objective was to evaluate international treaties, which carry legal obligations, for EESCA-related text, and develop a human rights-based framework to support EESCA advancement and advocacy...
February 8, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28178636/comparison-of-three-corrosion-inhibitors-in-simulated-partial-lead-service-line-replacements
#14
Aki Kogo, Sarah Jane Payne, Robert C Andrews
Partial lead service line replacements (PLSLR) were simulated using five recirculating pipe loops treated with either zinc orthophosphate (1mg/L as P), orthophosphate (1mg/L as P) or sodium silicate (10mg/L). Two pipe loops served as "inhibitor-free" (Pb-Cu) and "galvanic free" (Pb-PVC) controls. Changes in water quality (CSMR [0.2 or 1], conductivity [≈330mS/cm or ≈560mS/cm], chlorine [1.4mg/L]) were not observed to provide a significant impact on lead or copper release, although galvanic corrosion was shown to be a driving factor...
January 23, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/28176264/the-integration-of-neural-information-by-a-passive-kinetic-stimulus-and-galvanic-vestibular-stimulation-in-the-lateral-vestibular-nucleus
#15
Gyutae Kim, Kyu-Sung Kim, Sangmin Lee
Despite an easy control and the direct effects on vestibular neurons, the clinical applications of galvanic vestibular stimulation (GVS) have been restricted because of its unclear activities as input. On the other hand, some critical conclusions have been made in the peripheral and the central processing of neural information by kinetic stimuli with different motion frequencies. Nevertheless, it is still elusive how the neural responses to simultaneous GVS and kinetic stimulus are modified during transmission and integration at the central vestibular area...
February 7, 2017: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/28170053/substance-use-or-abuse-internet-use-psychopathology-and-suicidal-ideation-in-adolescents
#16
Matilde Bousoño Serrano, Susana Al-Halabí, Patricia Burón, Marlen Garrido, Eva María Díaz-Mesa, Gonzalo Galván, Leticia García-Álvarez, Vladimir Carli, Christina Hoven, Marco Sarchiapone, Danuta Wasserman, Manuel Bousoño, María Paz García-Portilla, Celso Iglesias, Pilar Alejandra Sáiz, Julio Bobes
Substance and Internet use or abuse, psychopathology and suicidal ideation appear to be related. The aim of this study is to investigate the association between use of psychotropic substances, inadequate Internet use, suicidal ideation and other psychopathological symptoms within the adolescent population. The present study was carried out as part of the Saving and Empowering Young Lives in Europe (SEYLE) project, funded by the European Union. The sample is composed of 1026 adolescents aged between 14 and 16 years from 12 state schools in Asturias (530 men and 496 women)...
January 12, 2017: Adicciones
https://www.readbyqxmd.com/read/28169553/improvements-in-health-related-quality-of-life-cardio-metabolic-health-and-fitness-in-postmenopausal-women-after-an-exercise-plus-health-promotion-intervention-a-randomized-controlled-trial
#17
Mercedes Vélez Toral, Débora Godoy-Izquierdo, Nicolás Mendoza Ladrón de Guevara, Carlos de Teresa Galván, Alberto Salamanca Ballesteros, Juan F Godoy García
BACKGROUND: This study explored multidimensional outcomes that were derived from the adherence to regular exercise among previously sedentary postmenopausal 45-64 years old women who engaged in a ~20-week exercise programme. METHODS: A RCT with between-group (intervention and control women) and within-subject measures (baseline, postintervention and 3-month and 12-month follow-ups) wasconducted. HRQoL and several indicators of cardio-metabolic status and fitness were assessed...
February 7, 2017: Journal of Physical Activity & Health
https://www.readbyqxmd.com/read/28167822/accelerating-corrosion-of-pure-magnesium-co-implanted-with-titanium-in-vivo
#18
Peng Hou, Pei Han, Changli Zhao, Hongliu Wu, Jiahua Ni, Shaoxiang Zhang, Jingyi Liu, Yuanzhuang Zhang, Haidong Xu, Pengfei Cheng, Shen Liu, Yufeng Zheng, Xiaonong Zhang, Yimin Chai
Magnesium is a type of reactive metal, and is susceptible to galvanic corrosion. In the present study, the impact of coexistence of Ti on the corrosion behavior of high purity Mg (HP Mg) was investigated both in vitro and in vivo. Increased corrosion rate of HP Mg was demonstrated when Mg and Ti discs were not in contact. The in vivo experiments further confirmed accelerating corrosion of HP Mg screws when they were co-implanted with Ti screws into Sprague-Dawley rats' femur, spacing 5 and 10 mm. Micro CT scan and 3D reconstruction revealed severe corrosion morphology of HP Mg screws...
February 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28167225/no-child-left-behind-liver-transplantation-in-critically-ill-children
#19
Abbas Rana, Michael Kueht, Moreshwar Desai, Fong Lam, Tamir Miloh, Jennifer Moffett, N Thao N Galvan, Ronald Cotton, Christine O'Mahony, John Goss
BACKGROUND: Advances in critical care prolong survival in children with liver failure, allowing more critically ill children to undergo liver transplantation (OLT). In order to justify the use of a scarce donor resource and avoid futile transplants, we sought to determine the survival in children who undergo OLT while receiving pre-OLT critical care. STUDY DESIGN: We analyzed 13,723 pediatric OLTs using the UNOS database from 1987-2015, including 6,746 recipients in the MELD/PELD era (2002-2015)...
January 5, 2017: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/28162895/the-brain-basis-for-misophonia
#20
Sukhbinder Kumar, Olana Tansley-Hancock, William Sedley, Joel S Winston, Martina F Callaghan, Micah Allen, Thomas E Cope, Phillip E Gander, Doris-Eva Bamiou, Timothy D Griffiths
Misophonia is an affective sound-processing disorder characterized by the experience of strong negative emotions (anger and anxiety) in response to everyday sounds, such as those generated by other people eating, drinking, chewing, and breathing [1-8]. The commonplace nature of these sounds (often referred to as "trigger sounds") makes misophonia a devastating disorder for sufferers and their families, and yet nothing is known about the underlying mechanism. Using functional and structural MRI coupled with physiological measurements, we demonstrate that misophonic subjects show specific trigger-sound-related responses in brain and body...
February 1, 2017: Current Biology: CB
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