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https://www.readbyqxmd.com/read/27921172/erratum-to-parp10-deficiency-manifests-by-severe-developmental-delay-and-dna-repair-defect
#1
Maher Awni Shahrour, Claudia M Nicolae, Simon Edvardson, Motee Ashhab, Adri M Galvan, Daniel Constantin, Bassam Abu-Libdeh, George-Lucian Moldovan, Orly Elpeleg
No abstract text is available yet for this article.
December 6, 2016: Neurogenetics
https://www.readbyqxmd.com/read/27918647/a-droplet-based-high-throughput-sers-platform-on-a-droplet-guiding-track-engraved-superhydrophobic-substrate
#2
Sera Shin, Jaehong Lee, Sanggeun Lee, Hyunchul Kim, Jungmok Seo, Dayeong Kim, Juree Hong, Soonil Lee, Taeyoon Lee
A novel droplet-based surface-enhanced Raman scattering (SERS) sensor for high-throughput real-time SERS monitoring is presented. The developed sensors are based on a droplet-guiding-track-engraved superhydrophobic substrate covered with hierarchical SERS-active Ag dendrites. The droplet-guiding track with a droplet stopper is designed to manipulate the movement of a droplet on the superhydrophobic substrate. The superhydrophobic Ag dendritic substrates are fabricated through a galvanic displacement reaction and subsequent self-assembled monolayer coating...
December 5, 2016: Small
https://www.readbyqxmd.com/read/27917787/effects-of-neurofeedback-therapy-in-healthy-young-subjects
#3
Sümeyra Altan, Bercim Berberoglu, Sinan Canan, Şenol Dane
PURPOSE: Neurofeedback refers to a form of operant conditioning of electrical brain activity, in which desirable brain activity is rewarded and undesirable brain activity is inhibited. The research team aimed to examine the efficacy of neurofeedback therapy on electroencephalogram (EEG) for heart rate, electrocardiogram (ECG) and galvanic skin resistance (GSR) parameters in a healthy young male population. METHODS: Forty healthy young male subjects aged between 18 to 30 years participated in this study...
December 1, 2016: Clinical and Investigative Medicine. Médecine Clinique et Experimentale
https://www.readbyqxmd.com/read/27917564/mind-the-gap-in-clinical-trials-a-participatory-action-analysis-with-citizen-collaborators
#4
Amy Price, Su May Liew, Jo Kirkpatrick, Jazmin Price, Taylor Lopreto, Yasmin Nelken
What are the strengths, gaps, expectations, and barriers to research engagement in clinical trials as communicated through social media? Clinical trials test treatments to provide reliable information for safety and effectiveness. Trials are building blocks in which what is learned in earlier research can be used to improve treatments, compare alternatives, and improve quality of life. For 20 years, the percentages of clinical trials volunteers have decreased whereas the costs of running clinical trials have multiplied...
December 4, 2016: Journal of Evaluation in Clinical Practice
https://www.readbyqxmd.com/read/27908447/prevalence-of-comorbidities-and-the-prognostic-value-of-the-profund-index-in-a-hospital-cardiology-unit
#5
M A López-Garrido, I Antequera Martín-Portugués, V M Becerra-Muñoz, H N Orellana-Figueroa, F J Sánchez-Lora, L Morcillo-Hidalgo, M F Jiménez-Navarro, J J Gómez-Doblas, E de Teresa-Galván, J M García-Pinilla
INTRODUCTION: The aim of this study was to understand the prevalence of comorbidities and the usefulness of the PROFUND index for the prognostic stratification of patients with comorbidities in a hospital cardiology unit. PATIENTS AND METHODS: We consecutively analysed all patients hospitalized in 2012 in the department of cardiology. We recorded the comorbidities, length of stay, hospital mortality, Charlson indices and PROFUND indices. In the patients with comorbidities, we also recorded the readmissions and mortality during a 1-year follow-up...
November 28, 2016: Revista Clínica Española
https://www.readbyqxmd.com/read/27900300/treatment-of-proximal-hamstring-tendinopathy-related-sciatic-nerve-entrapment-presentation-of-an-ultrasound-guided-intratissue-percutaneous-electrolysis-application
#6
Gabriele Mattiussi, Carlos Moreno
BACKGROUND: Proximal Hamstring Tendinopathy-related Sciatic Nerve Entrapment (PHTrSNE) is a neuropathy caused by fibrosis interposed between the semimembranosus tendon and the sciatic nerve, at the level of the ischial tuberosity. METHODS: Ultrasound-guided Intratissue Percutaneous Electrolysis (US-guided EPI) involves galvanic current transfer within the treatment target tissue (fibrosis) via a needle 0.30 to 0.33 mm in diameter. The galvanic current in a saline solution instantly develops the chemical process of electrolysis, which in turn induces electrochemical ablation of fibrosis...
April 2016: Muscles, Ligaments and Tendons Journal
https://www.readbyqxmd.com/read/27900107/preclinical-trial-on-the-use-of-doxycycline-for-the-treatment-of-adenocarcinoma-of-the-duodenum
#7
Hector R Galván-Salazar, Alejandro D Soriano-Hernández, Daniel A Montes-Galindo, Gabriel Ceja Espíritu, José Guzman-Esquivel, Iram P Rodríguez-Sánchez, Oscar A Newton-Sánchez, Margarita L Martinez-Fierro, Xóchitl G Briseño Gómez, Augusto Rojas-Martínez, Iván Delgado-Enciso
Adenocarcinoma of the duodenum comprises 50-70% of duodenal tumors. There is an increase in extracellular matrix metalloproteinases in this disease and it has been suggested that they play an important role in the development and pathology. Therefore, new therapeutic recommendations based on inhibitors of these enzymes, such as doxycycline, are under investigation. The cytotoxic effect of doxycycline was evaluated in the HuTu-80 duodenal adenocarcinoma cell line and its antitumor effect was determined in an immunodeficient murine model...
November 2016: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/27894518/radiation-maculopathy-treated-with-intravitreal-bevacizumab
#8
J L Sánchez-Vicente, A Muñoz-Morales, M P Galván-Carrasco, A Castilla-Lázpita, C Vital-Berral, A Alfaro-Juárez, T Rueda-Rueda
CASE REPORT: A 47 year-old woman with a choroidal melanoma developed a macular oedema secondary to radiation therapy 75 months after brachytherapy plaque. The patient received 3 intravitreal Bevacizumab injections. DISCUSSION: The patient had a good response to bevacizumab treatment. In fact, there was a reduction in the macular oedema measured by optical coherence tomography (OCT) scan, as well as an improvement in best corrected visual acuity. There was no recurrence of macular oedema, and visual acuity remained stable after 3-years follow-up...
November 25, 2016: Archivos de la Sociedad Española de Oftalmología
https://www.readbyqxmd.com/read/27894221/effectiveness-and-safety-of-pemetrexed-for-non-small-cell-lung-cancer-in-the-andalusian-public-health-system
#9
María Antonia Pérez-Moreno, Jesús Cotrina-Luque, Mercedes Galván-Banqueri, Sandra Flores-Moreno, Francisco Javier Bautista-Paloma, Miguel Ángel Calleja-Hernández
OBJECTIVE: To evaluate effectiveness and safety profile of pemetrexed in patients with locally advanced or metastatic non-small-cell lung cancer (NSCLC) when it´s used on real clinical practice in Andalusia (a Spanish region with 8.5 million inhabitants, 2014 census data). METHODS: An observational multicentre retrospective study was conducted. Adult patients with locally advanced/metastatic NSCLC who received pemetrexed in any hospital in the Andalusian Public Health System during the last term of 2011 were included...
November 1, 2016: Farmacia Hospitalaria
https://www.readbyqxmd.com/read/27894051/the-influence-of-sr-on-the-microstructure-degradation-and-stress-corrosion-cracking-of-the-mg-alloys-zk40xsr
#10
Lianxi Chen, Yuanhong Bin, Wenqi Zou, Xiaojian Wang, Wei Li
In the present work, new magnesium (Mg) alloys (Mg-4Zn-0.6Zr-xSr, x=0, 0.4, 0.8, 1.2, 1.6wt%; ZK40xSr) were prepared and studied as potential biodegradable materials. The influence of strontium (Sr) addition on the properties of the new Mg alloys was investigated, which included microstructure, corrosion degradation, and the stress corrosion cracking (SCC) susceptibility. The average grain size of the ZK40Sr was approximately 100µm, which was significantly smaller than that of ZK40 alloy without Sr (402.3±40...
November 18, 2016: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/27893880/protective-prevention-effects-on-the-association-of-poverty-with-brain-development
#11
Gene H Brody, Joshua C Gray, Tianyi Yu, Allen W Barton, Steven R H Beach, Adrianna Galván, James MacKillop, Michael Windle, Edith Chen, Gregory E Miller, Lawrence H Sweet
Importance: This study was designed to determine whether a preventive intervention focused on enhancing supportive parenting could ameliorate the association between exposure to poverty and brain development in low socioeconomic status African American individuals from the rural South. Objective: To determine whether participation in an efficacious prevention program designed to enhance supportive parenting for rural African American children will ameliorate the association between living in poverty and reduced hippocampal and amygdalar volumes in adulthood...
November 28, 2016: JAMA Pediatrics
https://www.readbyqxmd.com/read/27881873/induction-of-iron-excess-restricts-malignant-plasma-cells-expansion-and-potentiates-bortezomib-effect-in-models-of-multiple-myeloma
#12
J Bordini, S Galvan, M Ponzoni, M T S Bertilaccio, M Chesi, P L Bergsagel, C Camaschella, A Campanella
Leukemia accepted article preview online, 24 November 2016. doi:10.1038/leu.2016.346.
November 24, 2016: Leukemia: Official Journal of the Leukemia Society of America, Leukemia Research Fund, U.K
https://www.readbyqxmd.com/read/27871998/isolation-of-a-sulfide-producing-bacterial-consortium-from-cooling-tower-water-evaluation-of-corrosive-effects-on-galvanized-steel
#13
Esra Ilhan-Sungur, Derya Ozuolmez, Ayşın Çotuk, Nurhan Cansever, Gerard Muyzer
Sulfidogenic Clostridia and sulfate reducing bacteria (SRB) often cohabit in nature. The presence of these microorganisms can cause microbially influenced corrosion (MIC) of materials in different ways. To investigate this aspect, bacteria were isolated from cooling tower water and used in corrosion tests of galvanized steel. The identity of the isolates was determined by comparative sequence analysis of PCR-amplified 16S rDNA gene fragments, separated by denaturing gradient gel electrophoresis (DGGE). This analysis showed that, in spite of the isolation process, colonies were not pure and consisted of a mixture of bacteria affiliated with Desulfosporosinus meridiei and Clostridium sp...
November 18, 2016: Anaerobe
https://www.readbyqxmd.com/read/27869225/noisy-galvanic-vestibular-stimulation-induces-a-sustained-improvement-in-body-balance-in-elderly-adults
#14
Chisato Fujimoto, Yoshiharu Yamamoto, Teru Kamogashira, Makoto Kinoshita, Naoya Egami, Yukari Uemura, Fumiharu Togo, Tatsuya Yamasoba, Shinichi Iwasaki
Vestibular dysfunction causes postural instability, which is prevalent in the elderly. We previously showed that an imperceptible level of noisy galvanic vestibular stimulation (nGVS) can improve postural stability in patients with bilateral vestibulopathy during the stimulus, presumably by enhancing vestibular information processing. In this study, we investigated the after-effects of an imperceptible long-duration nGVS on body balance in elderly adults. Thirty elderly participants underwent two nGVS sessions in a randomised order...
November 21, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27858399/a-modified-chemical-protocol-of-decellularization-of-rat-sciatic-nerve-and-its-recellularization-with-mesenchimal-differentiated-schwann-like-cells-morphological-and-functional-assessments
#15
M M García-Pérez, H G Martínez-Rodríguez, G G López-Guerra, A Soto-Domínguez, S L Said-Fernández, R Morales-Avalos, R E Elizondo-Omaña, R Montes-de-Oca-Luna, S Guzmán-López, M L Castillo-Galván, O F Mendoza-Lemus, F Vílchez-Cavazos
The functional reconstruction of large neural defects usually requires the use of peripheral nerve autografts, though these have certain limitations. As a result, interest in new alternatives for autograft development has risen. The acellular peripheral nerve graft is an alternative for peripheral nerve injury repair, but to date there is not a standardized chemical decellularization method widely accepted. The objective of this study was to propose a modified chemical protocol of decellularization of rat sciatic nerve and its recellularization in vitro with mesenchimal differentiated Schwann-like cells...
November 18, 2016: Histology and Histopathology
https://www.readbyqxmd.com/read/27856559/predicting-women-s-utilization-of-primary-care-mental-health-services-in-mexico-city
#16
Karla Mendoza, Arianna Ulloa, Nayelhi Saavedra, Jorge Galván, Shoshana Berenzon
OBJECTIVE: To analyze factors associated with and predicting Mexican women seeking primary care mental health services (PCMHS) and provide suggestions to increase PCMHS utilization. METHOD: We administered a questionnaire to (N = 456) female patients in Mexico City primary care clinics. We conducted chi-square analyses of seeking PCMHS and sociodemographic variables, perceptions of and experiences with PCMHS. Our results and literature review guided our logistic regression model...
November 17, 2016: Journal of Primary Care & Community Health
https://www.readbyqxmd.com/read/27854082/randomized-controlled-trial-comparing-the-effectiveness-of-the-ultrasound-guided-galvanic-electrolysis-technique-usget-versus-conventional-electro-physiotherapeutic-treatment-on-patellar-tendinopathy
#17
F Abat, J L Sánchez-Sánchez, A M Martín-Nogueras, J I Calvo-Arenillas, J Yajeya, R Méndez-Sánchez, J C Monllau, P E Gelber
BACKGROUND: Patellar tendinopathy has a high prevalence rate among athletes. Different therapeutic options can be found in the current literature, but none of them has been clearly established as the gold standard. The purpose of this study is to compare, in a randomized controlled trial, the clinical efficacy of eccentric exercise combined with either an ultrasound-guided galvanic electrolysis technique (USGET) or conventional electrophysiotherapy to treat patellar tendinopathy. METHODS: Sixty patients diagnosed with patellar tendinopathy were randomized into two groups...
December 2016: Journal of Experimental Orthopaedics
https://www.readbyqxmd.com/read/27851831/speeding-access-to-vaccines-and-medicines-in-low-and-middle-income-countries-a-case-for-change-and-a-framework-for-optimized-product-market-authorization
#18
Vincent Ahonkhai, Samuel F Martins, Alexandre Portet, Murray Lumpkin, Dan Hartman
BACKGROUND: The United Nations Millennium Development Goals galvanized global efforts to alleviate suffering of the world's poorest people through unprecedented public-private partnerships. Donor aid agencies have demonstrably saved millions of lives that might otherwise have been lost to disease through increased access to quality-assured vaccines and medicines. Yet, the introduction of these health interventions in low- and middle-income countries (LMICs) continues to face a time lag due to factors which remain poorly understood...
2016: PloS One
https://www.readbyqxmd.com/read/27847985/acute-peripheral-vestibular-deficit-increases-redundancy-in-random-number-generation
#19
Ivan Moser, Dominique Vibert, Marco D Caversaccio, Fred W Mast
Unilateral peripheral vestibular deficit leads to broad cognitive difficulties and biases in spatial orientation. More specifically, vestibular patients typically show a spatial bias toward their affected ear in the subjective visual vertical, head and trunk orientation, fall tendency, and walking trajectory. By means of a random number generation task, we set out to investigate how an acute peripheral vestibular deficit affects the mental representation of numbers in space. Furthermore, the random number generation task allowed us to test if patients with peripheral vestibular deficit show evidence of impaired executive functions while keeping the head straight and while performing active head turns...
November 15, 2016: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/27846956/trichoscopy-of-dissecting-cellulitis-of-the-scalp-exclamation-mark-hairs-and-white-dots-as-markers-of-disease-chronicity
#20
Gonzalo Segurado-Miravalles, Francisco Camacho-Martınez, Salvador Arias-Santiago, Rita Rodrigues-Barata, Cristina Serrano-Falcón, Oscar Muñoz Moreno-Arrones, Pedro Jaén Olasolo, Sergio Vañó-Galván
No abstract text is available yet for this article.
December 2016: Journal of the American Academy of Dermatology
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