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Kellgren lawrence knee hip

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https://www.readbyqxmd.com/read/27894173/open-wedge-high-tibial-osteotomy-and-combined-arthroscopic-surgery-in-severe-medial-osteoarthritis-and-varus-malalignment-minimum-5-year-results
#1
Moon-Jib Yoo, Yong-Eun Shin
Purpose: To evaluate the radiologic and functional outcomes of medial open wedge high tibial osteotomy (HTO) combined with arthroscopic procedure in patients with medial osteoarthritis. Materials and Methods: From June 1996 to March 2010, 26 patients (32 knees) who underwent medial open wedge osteotomy and arthroscopic operation for medial osteoarthritis were retrospectively reviewed. Measurements included hip-knee-ankle (HKA) angle, femorotibial angle, medial proximal tibial angle, posterior tibial slope angle, and Kellgren-Lawrence grade...
December 1, 2016: Knee Surgery & related Research
https://www.readbyqxmd.com/read/27864563/a-replication-study-and-meta-analysis-of-mitochondrial-dna-variants-in-the-radiographic-progression-of-knee-osteoarthritis
#2
Mercedes Fernández-Moreno, Angel Soto-Hermida, María E Vázquez-Mosquera, Estefanía Cortés-Pereira, Sonia Pértega, Sara Relaño, Natividad Oreiro-Villar, Carlos Fernández-López, Francisco J Blanco, Ignacio Rego-Pérez
OBJECTIVE: To conduct a replication study and meta-analysis involving the study of mtDNA variants in the radiographic progression of OA in different cohorts worldwide, including Cohort Hip and Cohort Knee (CHECK), the OA Initiative and a cohort from Spain. METHODS: The influence of the haplogroups in the rate of radiographic progression at 96 months in 431 subjects from CHECK was assessed in terms of Kellgren and Lawrence (KL) grade. Progression was defined as a change from KL ⩾ 1 at baseline to any higher grade during the follow-up...
November 17, 2016: Rheumatology
https://www.readbyqxmd.com/read/27751171/activation-of-calcitonin-gene-related-peptide-signaling-through-the-prostaglandin-e2-ep1-ep2-ep4-receptor-pathway-in-synovium-of-knee-osteoarthritis-patients
#3
Atsushi Minatani, Kentaro Uchida, Gen Inoue, Shotaro Takano, Jun Aikawa, Masayuki Miyagi, Hisako Fujimaki, Dai Iwase, Kenji Onuma, Toshihide Matsumoto, Masashi Takaso
BACKGROUND: Calcitonin gene-related peptide (CGRP) is a 37-amino-acid vasodilatory neuropeptide that binds to receptor activity-modifying protein 1 (RAMP1) and the calcitonin receptor-like receptor (CLR). Clinical and preclinical evidence suggests that CGRP is associated with hip and knee joint pain; however, the regulation mechanisms of CGRP/CGRP receptor signaling in synovial tissue are not fully understood. METHODS: Synovial tissues were harvested from 43 participants with radiographic knee osteoarthritis (OA; unilateral Kellgren/Lawrence (K/L) grades 3-4) during total knee arthroplasty...
October 17, 2016: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/27746495/epidemiology-of-knee-osteoarthritis-in-india-and-related-factors
#4
Chandra Prakash Pal, Pulkesh Singh, Sanjay Chaturvedi, Kaushal Kumar Pruthi, Ashok Vij
BACKGROUND: Among the chronic rheumatic diseases, hip and knee osteoarthritis (OA) is the most prevalent and is a leading cause of pain and disability in most countries worldwide. Its prevalence increases with age and generally affects women more frequently than men. OA is strongly associated with aging and heavy physical occupational activity, a required livelihood for many people living in rural communities in developing countries. Determining region-specific OA prevalence and risk factor profiles will provide important information for planning future cost effective preventive strategies and health care services...
September 2016: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/27648573/radiographic-hip-or-knee-osteoarthritis-and-the-ability-to-drive
#5
Maximilian von Bernstorff, Martina Feierabend, Maurice Jordan, Christopher Glatzel, Ingmar Ipach, Ulf Krister Hofmann
The question of whether patients with musculoskeletal disorders are fit to drive is of paramount importance for them and frequently is directed to the treating orthopedic specialist. Although perioperative braking performance has been increasingly investigated in recent years, scientific data on braking safety in individuals with osteoarthritis (OA) are scarce. This study analyzed the braking performance of 158 patients with OA of the right or left knee or hip and compared the results with radiographic OA grading according to the Kellgren-Lawrence classification scale...
September 19, 2016: Orthopedics
https://www.readbyqxmd.com/read/27558412/central-sensitization-as-a-determinant-of-patients-benefit-from-total-hip-and-knee-replacement
#6
V Wylde, A Sayers, A Odutola, R Gooberman-Hill, P Dieppe, A W Blom
BACKGROUND: Discrepancies exist between osteoarthritic joint changes and pain severity before and after total hip (THR) and knee (TKR) replacement. This study investigated whether the interaction between pre-operative widespread hyperalgesia and severity of radiographic osteoarthritis (OA) was associated with pain severity before and after joint replacement. METHODS: Data were analysed from 232 patients receiving THR and 241 receiving TKR. Pain was assessed pre-operatively and at 12 months post-operatively using the WOMAC Pain Scale...
August 24, 2016: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/27410385/factors-for-assessing-the-effectiveness-of-early-rehabilitation-after-minimally-invasive-total-knee-arthroplasty-a-prospective-cohort-study
#7
Tetsuya Amano, Kotaro Tamari, Shigeharu Tanaka, Shigehiro Uchida, Hideyuki Ito, Shinya Morikawa, Kenji Kawamura
The effectiveness of current rehabilitation programs is supported by high-level evidence from the results of randomized controlled trials, but an increasing number of patients are not discharged from the hospital because of the schedule of the critical path (CP). The present study aimed to determine which factors can be used to assess the effectiveness of early rehabilitation. We enrolled 123 patients with medial knee osteoarthritis (OA) who had undergone unilateral minimally invasive total knee arthroplasty for the first time...
2016: PloS One
https://www.readbyqxmd.com/read/27378638/preoperative-predictors-of-pain-catastrophizing-anxiety-and-depression-in-patients-undergoing-total-joint-arthroplasty
#8
Thomas J Wood, Patrick Thornley, Danielle Petruccelli, Conrad Kabali, Mitch Winemaker, Justin de Beer
BACKGROUND: The relationship between pain catastrophizing and emotional disorders including anxiety and depression in osteoarthritic patients undergoing total joint arthroplasty (TJA) is an emerging area of study. The purpose of this study was to examine the association of these factors with preoperative patient characteristics. METHODS: A prospective cohort study of preoperative TJA patients using the Pain Catastrophizing Scale (PCS) and Hospital Anxiety and Depression Scale (HADS-A/HADS-D) was conducted...
June 3, 2016: Journal of Arthroplasty
https://www.readbyqxmd.com/read/27210234/fascial-manipulation-associated-with-standard-care-compared-to-only-standard-postsurgical-care-for-total-hip-arthroplasty-a%C3%A2-randomized-controlled-trial
#9
Massimo Busato, Cristian Quagliati, Lara Magri, Alessandra Filippi, Alberto Sanna, Mirco Branchini, Aurelie Marie Marchand, Antonio Stecco
BACKGROUND: Postsurgical physiotherapy programs after total hip arthroplasty (THA) show important differences between types and numbers of treatment sessions. To increase functional recovery in postsurgical patients, manual therapy can be added to traditional physiotherapy programs. Fascial Manipulation (FM) has been demonstrated to be effective in decreasing pain and increasing muscular capacity. OBJECTIVE: To compare the effectiveness of FM when added to a standard protocol of care...
May 19, 2016: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/26968694/severe-hand-osteoarthritis-strongly-correlates-with-major-joint-involvement-and-surgical-intervention
#10
Chitranjan S Ranawat, Caroline N Park, Peter B White, Morteza Meftah, Eric A Bogner, Amar S Ranawat
BACKGROUND: The presence of hand osteoarthritis (OA) increases the risk for developing OA in other major joints. Although genetic predisposition has been implicated in its causation, its exact role has yet to be established. The association of hand OA with symptomatic and asymptomatic major joints has not been previously studied. METHODS: Hundred consecutive patients had a hand photo taken for visual documentation of the hand joints. Radiographs of hand and all major symptomatic joints were analyzed and classified using the Kellgren-Lawrence scale by 2 independent observers including an orthopedic radiologist...
August 2016: Journal of Arthroplasty
https://www.readbyqxmd.com/read/26887576/effect-of-aqua-cycling-on-pain-and-physical-functioning-compared-with-usual-care-in-patients-with-knee-osteoarthritis-study-protocol-of-a-randomised-controlled-trial
#11
RANDOMIZED CONTROLLED TRIAL
Stefanie Rewald, Ilse Mesters, A F Lenssen, Pieter J Emans, Wiel Wijnen, Rob A de Bie
BACKGROUND: Over the last decade aquatic exercise has become more and more popular. One of the latest trends is aqua-cycling, where participants sit on a water-resistant stationary bike and, while immersed chest deep in the water, combine continuous cycling with upper body exercises that utilise water resistance. Since stationary cycling and aquatic exercises are frequently recommended to patients with knee osteoarthritis, combining both would seem an obvious step, and an aqua-cycling exercise programme for patients with knee osteoarthritis has indeed been developed...
February 18, 2016: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/26832187/association-between-hip-morphology-and-prevalence-clinical-severity-and-progression-of-hip-osteoarthritis-over-3-years-the-knee-and-hip-osteoarthritis-long-term-assessment-cohort-results
#12
Benjamin Bouyer, Bernard Mazieres, Francis Guillemin, Ronan Bouttier, Bruno Fautrel, Johanne Morvan, Jacques Pouchot, Anne-Christine Rat, Christian H Roux, Evelyne Verrouil, Alain Saraux, Joël Coste
OBJECTIVE: To assess the effects of variations in hip morphology on prevalence, clinical severity and progression of hip osteoarthritis. METHODS: From 2007 to 2009, we conducted a study of 242 patients aged between 40 and 75 years with symptomatic lower limb osteoarthritis, as part of a population-based osteoarthritis cohort study in France. Standard radiographs of both hips were obtained at baseline and at three years. The progression of hip osteoarthritis was evaluated according to the radiological Kellgren-Lawrence score (KL) and clinical severity from the scores on a Visual Analogic Scale (VAS) for pain recorded yearly...
July 2016: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/26712497/radiographic-measures-of-settlement-phenomenon-in-patients-with-medial-compartment-knee-osteoarthritis
#13
Tianhua Dong, Wei Chen, Fei Zhang, Bing Yin, Ye Tian, Yingze Zhang
In this study, we proposed for the first time the theory of "settlement phenomenon" in tibial plateau and carefully explored the role of settlement of tibial plateau in the occurrence and progression of medial compartment knee osteoarthritis (OA) through investigating the relationship between the degree of settlement and the radiographic severity of OA. One hundred twenty-seven patients with knee medial compartment OA were recruited and examined with weight-bearing radiographs of the entire lower limb. The radiographic severity of OA was evaluated using the Kellgren and Lawrence (KL) grading methods...
June 2016: Clinical Rheumatology
https://www.readbyqxmd.com/read/26669914/variations-in-hip-shape-are-associated-with-radiographic-knee-osteoarthritis-cross-sectional-and-longitudinal-analyses-of-the-johnston-county-osteoarthritis-project
#14
Amanda E Nelson, Yvonne M Golightly, Jordan B Renner, Todd A Schwartz, Felix Liu, John A Lynch, Jenny S Gregory, Richard M Aspden, Nancy E Lane, Joanne M Jordan
OBJECTIVE: Hip shape by statistical shape modeling (SSM) is associated with hip radiographic osteoarthritis (rOA). We examined associations between hip shape and knee rOA given the biomechanical interrelationships between these joints. METHODS: Bilateral baseline hip shape assessments [for those with at least 1 hip with a Kellgren-Lawrence arthritis grading scale (KL) 0 or 1] from the Johnston County Osteoarthritis Project were available. Proximal femur shape was defined on baseline pelvis radiographs and evaluated by SSM, producing mean shape and continuous variables representing independent modes of variation (14 modes = 95% of shape variance)...
February 2016: Journal of Rheumatology
https://www.readbyqxmd.com/read/26637677/are-lateral-compartment-osteophytes-a-predictor-for-lateral-cartilage-damage-in-varus-osteoarthritic-knees-data-from-the-osteoarthritis-initiative
#15
MULTICENTER STUDY
M Faschingbauer, L Renner, W Waldstein, F Boettner
We studied whether the presence of lateral osteophytes on plain radiographs was a predictor for the quality of cartilage in the lateral compartment of patients with varus osteoarthritic of the knee (Kellgren and Lawrence grade 2 to 3). The baseline MRIs of 344 patients from the Osteoarthritis Initiative (OAI) who had varus osteoarthritis (OA) of the knee on hip-knee-ankle radiographs were reviewed. Patients were categorised using the Osteoarthritis Research Society International (OARSI) osteophyte grading system into 174 patients with grade 0 (no osteophytes), 128 grade 1 (mild osteophytes), 28 grade 2 (moderate osteophytes) and 14 grade 3 (severe osteophytes) in the lateral compartment (tibia)...
December 2015: Bone & Joint Journal
https://www.readbyqxmd.com/read/26522138/25-hydroxyvitamin-d-and-osteoarthritis-a-meta-analysis-including-new-data
#16
Arjan P Bergink, M Carola Zillikens, Johannes P T M Van Leeuwen, Albert Hofman, André G Uitterlinden, Joyce B J van Meurs
OBJECTIVES: To study the relationship between 25-hydroxy (OH) vitamin D serum levels and osteoarthritis (OA) of the knee, hip, and hand in a meta-analysis, with updated and expanded results of our previous study. METHODS: Pubmed was searched from February 1975 to December 2014 for articles assessing the relationship between vitamin D levels and OA. In our meta-analysis, 6 cross-sectional and 6 longitudinal studies were included. The number of subjects in these studies ranged from 99 to 1248 subjects...
April 2016: Seminars in Arthritis and Rheumatism
https://www.readbyqxmd.com/read/26520886/femoro-tibial-knee-osteoarthritis-one-or-two-x-rays-results-from-a-population-based-study
#17
COMPARATIVE STUDY
Christian-Hubert Roux, Bernard Mazieres, Evelyne Verrouil, Anne-Christine Rat, Patrice Fardellone, Bruno Fautrel, Jacques Pouchot, Alain Saraux, Francis Guillemin, Liana Euller-Ziegler, Joël Coste
OBJECTIVE: Our objective was to compare the use of both anteroposterior (AP) extended-knee X-ray and semi-flexed X-ray (current gold standard) versus the use of semi-flexed X-ray alone to detect femoro-tibial osteoarthritis (OA). METHODS: Individuals 40 to 75 years of age with symptomatic hip and/or knee OA (Kellgren/Lawrence [KL] score≥2) were recruited using a multiregional prevalence survey in France. Both AP and schuss X-rays were performed and read; two years later, the same examiner, blinded to the results of the first reading, performed a second reading of the schuss X-ray...
January 2016: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/26503347/efficacy-and-safety-of-low-dose-solumatrix-meloxicam-in-the-treatment-of-osteoarthritis-pain-a-12-week-phase-3-study
#18
RANDOMIZED CONTROLLED TRIAL
Roy Altman, Marc Hochberg, Allan Gibofsky, Mark Jaros, Clarence Young
OBJECTIVE: Nonsteroidal anti-inflammatory drugs (NSAIDs) such as meloxicam are commonly used to treat osteoarthritis (OA) but are associated with potentially serious dose-related adverse events (AEs). SoluMatrix meloxicam has been developed with the goal of enabling effective treatment at low doses. This phase 3 study evaluated the efficacy and safety of low-dose SoluMatrix meloxicam capsules 5 mg and 10 mg administered once daily for 12 weeks in patients with OA-related pain. RESEARCH DESIGN AND METHODS: This randomized, double-blind study enrolled patients ≥40 years of age with confirmed hip or knee OA (Kellgren-Lawrence grade II-III) who were chronic users of NSAIDs and/or acetaminophen for OA pain and had Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) pain subscale mean scores ≥40 mm...
December 2015: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/26484651/outcome-of-total-hip-arthroplasty-but-not-of-total-knee-arthroplasty-is-related-to-the-preoperative-radiographic-severity-of-osteoarthritis-a-prospective-cohort-study-of-573-patients
#19
COMPARATIVE STUDY
Claire Tilbury, Maarten J Holtslag, Rutger L Tordoir, Claudia S Leichtenberg, Suzan H M Verdegaal, Herman M Kroon, Marta Fiocco, Rob G H H Nelissen, Thea P M Vliet Vlieland
BACKGROUND AND PURPOSE: There is no consensus on the impact of radiographic severity of hip and knee osteoarthritis (OA) on the clinical outcome of total hip arthroplasty (THA) and total knee arthroplasty (TKA). We assessed whether preoperative radiographic severity of OA is related to improvements in functioning, pain, and health-related quality of life (HRQoL) 1 year after THA or TKA. PATIENTS AND METHODS: This prospective cohort study included 302 THA patients and 271 TKA patients with hip or knee OA...
February 2016: Acta Orthopaedica
https://www.readbyqxmd.com/read/26457483/osteoarthritis-in-latin-america-study-of-demographic-and-clinical-characteristics-in-3040-patients
#20
Anthony M Reginato, Humberto Riera, Mariflor Vera, Adrian R Torres, Rolando Espinosa, Jorge A Esquivel, Oscar Jair Felipe, Jorge Roman Blas, Oscar Rillo, Silvia Papasidero, Renee Souto, Cesar Rossi, José F Molina, Francisco Ballesteros, Francisco Radrigan, Marlene Guibert, Araceli Chico, María L Gil, Walter Camacho, Lorena Urioste, Abraham K Garcia, Isa Iraheta, Carmen E Gutierrez, Margarita Duarte, Oswaldo Castañeda, Ibsen Coimbra, Roberto Muñoz Louis, John Reveille, Maritza Quintero
BACKGROUND: Latin America is a heterogeneous region made up of different populations, cultures, latitudes, altitudes, and immigrants from different areas and ethnic groups. OBJECTIVE: The purpose of this study is to describe the clinical and demographic profile of patients with osteoarthritis (OA) evaluated by a selected group of rheumatologists in 13 Latin American countries. METHODS: A descriptive, observational, cross-sectional study was conducted in 13 Latin American countries of patients with symptomatic OA...
December 2015: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
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