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https://www.readbyqxmd.com/read/29457487/dementia-management-strategies-associated-with-neuropsychiatric-symptoms-of-elderly-people-with-alzheimer-s-disease
#1
Lais Lopes Delfino, Ricardo Shoiti Komatsu, Caroline Komatsu, Anita Liberalesso Neri, Meire Cachioni
This study aims to investigate the association between management and communication strategies and the presence of neuropsychiatric symptoms presented by elderly people with Alzheimer's disease. One hundred and thirty-four family caregivers answered a questionnaire with socio-demographic data and questions regarding the care context, the Small Communication Strategies Scale, the Dementia Management Strategy Scale, and the Neuropsychiatric Inventory. Caregivers used the criticism management strategy more when the elderly presented hallucination, agitation, depression, anxiety, irritability, nighttime behavior, and appetite abnormalities...
January 1, 2018: Dementia
https://www.readbyqxmd.com/read/29451843/caregiver-reactions-to-dementia-symptoms-effects-on-coping-repertoire-and-mental-health
#2
Jaclene A Zauszniewski, Nirmala Lekhak, Carol M Musil
Currently, 15 million informal caregivers, most of whom are women, provide care for older adults with dementia (Alzheimer's Disease Association, 2016). Caregiving for these individuals often creates distress and may adversely affect female caregivers' psychosocial and spiritual well-being. Approximately 35% of dementia caregivers complain of health deterioration after initiating caregiving responsibilities as compared to 19% of caregivers of older adults who do not have dementia (Alzheimer's Disease Association, 2016)...
February 16, 2018: Issues in Mental Health Nursing
https://www.readbyqxmd.com/read/29448970/dementia-clinical-trial-implications-of-mild-behavioral-impairment
#3
Moyra E Mortby, Sandra E Black, Serge Gauthier, David Miller, Anton Porsteinsson, Eric E Smith, Zahinoor Ismail
The World Alzheimer Report 2016 estimated that 47 million people are living with dementia worldwide (Alzheimer's Disease International, 2016). In the inaugural World Health Organization Ministerial Conference on Global Action against Dementia, six of the top ten research priorities were focused on prevention, identification, and reduction of dementia risk, and on delivery and quality of care for people with dementia and their carers (Shah et al., 2016). While the Lancet Neurology Commission has suggested that even minor advances to delay progression or ameliorate symptoms might have substantial financial and societal benefits (Winblad et al...
February 2018: International Psychogeriatrics
https://www.readbyqxmd.com/read/29446066/resource-use-during-the-last-6-months-of-life-of-individuals-dying-with-and-of-alzheimer-s-disease
#4
Kristof Faes, Joachim Cohen, Lieven Annemans
OBJECTIVES: To compare resource use during the last 6 months of life of individuals diagnosed with Alzheimer's disease (AD) but for whom AD was not formally identified as the underlying cause of death (dying with AD) with that of those who had AD as underlying cause of death (dying of AD). DESIGN: Full-population retrospective analysis. SETTING: Belgium. PARTICIPANTS: All Belgian decedents in 2012. MEASUREMENTS: We linked participants' healthcare, population, and death certificate data...
February 15, 2018: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/29442991/variation-in-residential-care-community-resident-characteristics-by-size-of-community-united-states-2016
#5
Christine Caffrey, Manisha Sengupta
More residents in residential care communities with more than 25 beds were aged 85 and over compared with smaller communities. A higher percentage of residents in communities with 4-25 beds were receiving Medicaid compared with residents in larger communities. The prevalence of Alzheimer disease and depression was higher among residents of communities with 4-25 beds than in larger communities, but the prevalence of cardiovascular disease was lower. The percentage of residents needing assistance with bathing, dressing, toileting, transferring, walking, or eating was highest in communities with 4-25 beds...
February 2018: NCHS Data Brief
https://www.readbyqxmd.com/read/29441654/effect-of-rivastigmine-on-plasma-butyrylcholine-esterase-activity-and-plasma-ghrelin-levels-in-patients-with-dementia-in-alzheimer-s-disease
#6
Atsushi Kuroda, Manabu Setoguchi, Yasushi Uchino, Kazuya Nagata, Daisuke Hokonohara
AIM: Alzheimer's disease causes loss of appetite, resulting in bodyweight reduction. This, in turn, causes progression of cognitive dysfunction and physical complications that hasten death. Earlier care for loss of appetite is essential in Alzheimer's disease management. Rivastigmine is a therapeutic agent for Alzheimer's disease that has dual inhibition effects on acetylcholine esterase and butyrylcholine esterase. Butyrylcholine esterase is known to degrade the gastric hormone, ghrelin, which regulates appetite; therefore, we considered that rivastigmine might have an effect on appetite...
February 14, 2018: Geriatrics & Gerontology International
https://www.readbyqxmd.com/read/29439340/implementation-of-an-occupational-therapy-program-for-alzheimer-s-disease-patients-in-france-patients-and-caregivers-perspectives
#7
Aline Corvol, Alix Netter, Arnaud Campeon, Dominique Somme
BACKGROUND: The French National Alzheimer Plan 2008-2012 created specialized Alzheimer teams, which provide up to 15 sessions of cognitive rehabilitation in the patient's home for 3 months. Sessions are conducted by an occupational therapist and a gerontological nursing assistant. OBJECTIVES: As the patient's experience is one determinant of successful implementation, we explored the usefulness of these teams as viewed by the patient and his or her main caregiver...
2018: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/29439335/abnormalities-of-resting-state-cortical-eeg-rhythms-in-subjects-with-mild-cognitive-impairment-due-to-alzheimer-s-and-lewy-body-diseases
#8
Claudio Babiloni, Claudio Del Percio, Roberta Lizio, Giuseppe Noce, Susanna Lopez, Andrea Soricelli, Raffaele Ferri, Maria Teresa Pascarelli, Valentina Catania, Flavio Nobili, Dario Arnaldi, Francesco Famà, Dag Aarsland, Francesco Orzi, Carla Buttinelli, Franco Giubilei, Marco Onofrj, Fabrizio Stocchi, Laura Vacca, Paola Stirpe, Peter Fuhr, Ute Gschwandtner, Gerhard Ransmayr, Heinrich Garn, Lucia Fraioli, Michela Pievani, Giovanni B Frisoni, Fabrizia D'Antonio, Carlo De Lena, Bahar Güntekin, Lutfu Hanoğlu, Erol Başar, Görsev Yener, Derya Durusu Emek-Savaş, Antonio Ivano Triggiani, Raffaella Franciotti, John Paul Taylor, Maria Francesca De Pandis, Laura Bonanni
The present study tested the hypothesis that cortical sources of resting state eyes-closed electroencephalographic (rsEEG) rhythms reveal different abnormalities in cortical neural synchronization in groups of patients with mild cognitive impairment due to Alzheimer's disease (ADMCI) and dementia with Lewy bodies (DLBMCI) as compared to cognitively normal elderly (Nold) subjects. Clinical and rsEEG data in 30 ADMCI, 23 DLBMCI, and 30 Nold subjects were available in an international archive. Age, gender, and education were carefully matched in the three groups...
2018: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/29437810/down-syndrome-with-posterior-cortical-atrophy
#9
Claire Boutoleau-Bretonnière, Amandine Pallardy
Down syndrome (DS) is caused by trisomy of chromosome 21. The average age of onset of Alzheimer's disease (AD) ranged from 50 to 55 years in DS, with early symptoms usually characterised by changes in behaviour and executive dysfunction. On the other hand, posterior cortical atrophy (PCA) is a rare neurodegenerative syndrome characterised by progressive impairment of visual functions in the absence of visual deficits and a pattern of atrophy involving posterior cortex. This syndrome is mostly caused by AD pathology...
February 8, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29426824/plasma-a%C3%AE-analysis-using-magnetically-labeled-immunoassays-and-pet-18f-florbetapir-binding-in-non-demented-patients-with-major-depressive-disorder
#10
Kuan-Yi Wu, Ing-Tsung Hsiao, Chia-Hsiang Chen, Chia-Yih Liu, Jung-Lung Hsu, Sheng-Yao Huang, Tzu-Chen Yen, Kun-Ju Lin
An increased level of brain amyloid deposition and a decreased level of cerebral spinal fluid (CSF) Aβ42 are currently considered reliable biomarkers of Alzheimer's disease (AD); however, the usefulness of plasma Aβ levels are not well-established. This study investigated the relationships between plasma Aβ levels and cerebral amyloidosis in 36 non-demented patients with major depressive disorder (MDD). All participants underwent 18F-florbetapir PET imaging and provided a blood sample at the same time for immunomagnetic reduction assay to measure the plasma levels of Aβ40 and Aβ42...
February 9, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29422020/cognitive-medicine-a-new-approach-in-health-care-science
#11
Anders Wallin, Petronella Kettunen, Per M Johansson, Ingibjörg H Jonsdottir, Christer Nilsson, Michael Nilsson, Marie Eckerström, Arto Nordlund, Lars Nyberg, Katharina S Sunnerhagen, Johan Svensson, Beata Terzis, Lars-Olof Wahlund, H Georg Kuhn
BACKGROUND: The challenges of today's society call for more knowledge about how to maintain all aspects of cognitive health, such as speed/attention, memory/learning, visuospatial ability, language, executive capacity and social cognition during the life course. MAIN TEXT: Medical advances have improved treatments of numerous diseases, but the cognitive implications have not been sufficiently addressed. Disability induced by cognitive dysfunction is also a major issue in groups of patients not suffering from Alzheimer's disease or related disorders...
February 8, 2018: BMC Psychiatry
https://www.readbyqxmd.com/read/29413393/the-broken-lens-of-bpsd-why-we-need-to-rethink-the-way-we-label-the-behavior-of-people-who-live-with-alzheimer-disease
#12
Susan Macaulay
For the past 20 years, the behaviors of people who live with dementia (PLWD) that others find challenging or problematic have primarily been ascribed to Alzheimer disease and related dementias and have been assessed through the biomedical lens of Behavioral and Psychological Symptoms of Dementia (BPSD). This has led to the root causes of these behaviors being overlooked, which in turn leaves them unaddressed. Further, using the artificial construct of BPSD has led to many PLWD being inappropriately prescribed (off-label) medications that are largely ineffective in resolving the behaviors because they do nothing to remedy the underlying psychosocial and environmental causes...
February 2018: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/29409161/triple-test-a-diagnostic-observation-can-detect-cognitive-impairment-in-older-adults
#13
Ahmet T Isik, Pinar Soysal, Derya Kaya, Cansu Usarel
BACKGROUND: A simple, quick, and efficient screening tool for detecting mild cognitive impairment (MCI) and Alzheimer's disease (AD) is essential, especially in the primary care setting. In this study, we examined the neuropsychological profiles of elderly patients and aimed to assess the diagnostic value of the triple test, comprised of the attended alone sign (AAS), head-turning sign, and applause sign (AS), for detecting MCI and AD. METHOD: Comprehensive geriatric assessment was performed in 354 elderly outpatients, and the presence or absence of AS, AAS and HTS was investigated...
February 6, 2018: Psychogeriatrics: the Official Journal of the Japanese Psychogeriatric Society
https://www.readbyqxmd.com/read/29407716/moderating-role-of-positive-aspects-of-caregiving-in-the-relationship-between-depression-in-persons-with-alzheimer-s-disease-and-caregiver-burden
#14
Haihong Xue, Junwei Zhai, Runlian He, Liye Zhou, Ruifeng Liang, Hongmei Yu
Improving caregivers' positive perception of their role may be important in reducing their subjective burden when caring for Alzheimer's disease (AD) patients with depression. The purpose of present study was to explore the moderating role of the positive aspects of caregiving (PAC) on the subjective burden on family caregivers when managing depressive behaviors. We conducted a cross-sectional study including 200 pairs of patients with mild AD and their caregivers from three communities and two hospitals in Taiyuan, China in October 2014...
March 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29406141/blending-the-liberal-arts-and-nursing-creating-a-portrait-for-the-21st-century
#15
Wendy Carter Kooken, Noël Kerr
The liberal arts and sciences serve as a core part of the educational discipline in nursing curriculum and are believed to undergird abilities for critical-thinking, creativity, and holistic care (Hermann, 2004; McKie, 2012). Over time, science has taken on a more central role in nursing education, despite the acknowledged importance and contributions of liberal arts. The humanities are an essential part of liberal arts education and generally include disciplines such as history, literature, religion, philosophy, architecture, or fine arts (e...
January 2018: Journal of Professional Nursing: Official Journal of the American Association of Colleges of Nursing
https://www.readbyqxmd.com/read/29405234/costs-and-resource-use-associated-with-alzheimer-s-disease-in-italy-results-from-an-observational-study
#16
G Bruno, M Mancini, G Bruti, G Dell'Agnello, C Reed
BACKGROUND: The GERAS II study aimed to assess societal costs and resource use associated with Alzheimer's disease (AD) for patients and their primary caregivers in Italy and Spain, stratified for different severity stages of AD at baseline. This report presents baseline results for Italy. DESIGN: GERAS II was a prospective, multicentre, observational study of routine care in AD. SETTING: Community-dwelling patients attending specialist secondary care centres (memory clinics/Alzheimer's Evaluation Units) and their primary informal caregivers were recruited into the study...
2018: Journal of Prevention of Alzheimer's Disease
https://www.readbyqxmd.com/read/29402165/a-deterioration-in-hearing-is-associated-with-functional-and-cognitive-impairments-difficulty-with-communication-and-greater-health-instability
#17
Nicole Williams, Dawn M Guthrie, Jacob G S Davidson, Kathryn Fisher, Lauren E Griffith
OBJECTIVES: To examine the relationship between hearing deterioration and several health-related outcomes among home care clients in Ontario. DESIGN: Longitudinal analysis was completed for clients with at least two comprehensive assessments. Hearing status, based on a single item, ranged from zero (no impairment) to three (highly impaired). Hearing deterioration was defined as at least a 1-point decline between subsequent assessments. RESULTS: Seven percent experienced a 1-point deterioration in hearing and roughly 1% had a 2/3-point decline...
February 1, 2018: Journal of Applied Gerontology: the Official Journal of the Southern Gerontological Society
https://www.readbyqxmd.com/read/29398519/compound-c-enhances-tau-phosphorylation-at-serine396-via-pi3k-activation-in-an-ampk-and-rapamycin-independent-way-in-differentiated-sh-sy5y-cells
#18
Shohreh Majd, Simon Koblar, John Power
Aggregation of hyperphosphorylated tau (p-tau) in the form of neurofibrillary tangles (NFT) is a main hallmark for Alzheimer's disease (AD). Activation of cellular metabolic axis, made of adenosine monophosphate kinase protein kinase (AMPK) and mammalian target of rapamycin (mTOR) have been implicated in generating tau pathology of AD. Thus, blocking either of these two proteins or both, are suggested as the future therapeutic approaches for AD. How and to what level these approaches could be applied, however are not entirely clear...
January 31, 2018: Neuroscience Letters
https://www.readbyqxmd.com/read/29396187/diabetes-care-and-dementia-among-older-adults-a-nationwide-3-year-longitudinal-study
#19
Matthieu Wargny, Adeline Gallini, Hélène Hanaire, Fati Nourhashemi, Sandrine Andrieu, Virginie Gardette
OBJECTIVES: To compare diabetes monitoring and the incidence of acute diabetic complications between patients with and without incident Alzheimer's Disease and Related Syndromes (ADRS). DESIGN: Longitudinal observational study from 2010 to 2014. SETTING: Data from the French national health system database. PARTICIPANTS: The France-Démence cohort: individuals aged 65 years or older suffering from incident ADRS, based on long-term disease registry, hospitalization for dementia, or antidementia drug delivery...
January 25, 2018: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/29390504/relationship-between-general-anesthesia-and-alzheimer-disease-a-protocol-for-a-systematic-review-and-meta-analysis
#20
Geun Joo Choi, Hyun Kang, Chong Wha Baek, Yong Hun Jung, Jeong Wook Kim, Young Cheol Woo
BACKGROUND: Alzheimer disease (AD) entails a long-term progressive decline in the cognitive ability to think and remember, and it has become a major concern for patients receiving surgery and anesthesia. However, studies investigating the relationship between general anesthesia and AD have yielded inconsistent results. Therefore, we plan to perform a systematic review and meta-analysis to determine the relationship between general anesthesia and AD, and to verify whether general anesthesia is an independent risk factor for AD...
December 2017: Medicine (Baltimore)
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