keyword
MENU ▼
Read by QxMD icon Read
search

Alzheimers care

keyword
https://www.readbyqxmd.com/read/29667427/do-older-adults-with-alzheimer-s-disease-engage-in-estate-planning-and-advance-care-planning-preparation
#1
Shinae Choi, Minjung Kim, Ian M McDonough
OBJECTIVES: This study investigated the estate planning and advance care planning (ACP) of older adults diagnosed with Alzheimer's disease (AD) for the presence of (1) a valid will, (2) a durable power of attorney for health care, and (3) a living will. METHOD: We analyzed 10,273 adults aged 65 and older from the 2012 Health and Retirement Study (HRS) using multilevel logistic regression. RESULTS: We found that a diagnosis of AD was significantly associated with the ACP variables...
April 18, 2018: Aging & Mental Health
https://www.readbyqxmd.com/read/29665395/label-free-colorimetric-sensor-for-sensitive-detection-of-choline-based-on-dnazyme-choline-oxidase-coupling
#2
Nasrin Nikzad, Zahra Karami
Changes in choline levels can be associated with diseases such as Alzheimer, Parkinson, Huntington, fatty liver, interstitial lung abnormalities, autism and so on. Therefore, quantitative determination of choline is important in biological and clinical analysis. So far, several methods have been investigated for measuring choline in the body fluids, each of which has disadvantages such as the need for specialist ability, complexity, and high cost. For this purpose, a facile and sensitive colorimetric biosensor based on DNAzyme-choline oxidase coupling used for the determination of choline...
April 14, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29663553/rapid-evidence-assessment-of-approaches-to-community-neurological-nursing-care-for-people-with-neurological-conditions-post-discharge-from-acute-care-hospital
#3
REVIEW
Judith Dianne Pugh, Kathleen McCoy, Anne M Williams, Brenda Bentley, Leanne Monterosso
Neurological conditions represent leading causes of non-fatal burden of disease that will consume a large proportion of projected healthcare expenditure. Inconsistent access to integrated healthcare and other services for people with long-term neurological conditions stresses acute care services. The purpose of this rapid evidence assessment, conducted February-June 2016, was to review the evidence supporting community neurological nursing approaches for patients with neurological conditions post-discharge from acute care hospitals...
April 16, 2018: Health & Social Care in the Community
https://www.readbyqxmd.com/read/29660938/the-alzheimer-s-disease-assessment-scale-cognitive-subscale-adas-cog-modifications-and-responsiveness-in-pre-dementia-populations-a-narrative-review
#4
Jacqueline K Kueper, Mark Speechley, Manuel Montero-Odasso
The Alzheimer's Disease Assessment Scale- Cognitive Subscale (ADAS-Cog) was developed in the 1980s to assess the level of cognitive dysfunction in Alzheimer's disease. Advancements in the research field have shifted focus toward pre-dementia populations, and use of the ADAS-Cog has extended into these pre-dementia studies despite concerns about its ability to detect important changes at these milder stages of disease progression. If the ADAS-Cog cannot detect important changes, our understanding of pre-dementia disease progression may be compromised and trials may incorrectly conclude that a novel treatment approach is not beneficial...
April 11, 2018: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/29660933/medical-comorbidity-in-alzheimer-s-disease-a-nested-case-control-study
#5
Jen-Hung Wang, Ya-Ju Wu, Boon Lead Tee, Raymond Y Lo
BACKGROUND: Little is known about the distribution of medical comorbidities in Alzheimer's disease (AD). OBJECTIVE: We aimed to describe the comorbidity pattern of AD in a nested case-control study. METHODS: Incident AD cases were identified by International Classification of Diseases codes in a random sample of 2 million individuals in Taiwan National Health Insurance program during 2001-2011. We further restricted cases to those treated with AD drugs of approved reimbursement...
April 11, 2018: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/29659206/effects-of-antipsychotics-on-secular-mortality-trends-in-patients-with-alzheimer-s-disease
#6
René Ernst Nielsen, Jan B Valentin, Annette Lolk, Kjeld Andersen
OBJECTIVE: To investigate secular changes in mortality rates between patients with Alzheimer's disease (AD) and the general population as well as changes in antipsychotic drug treatment and the association between drug treatment and mortality in patients with AD in Denmark during a 12-year study period. METHODS: This nationwide, retrospective cohort study identified all-cause mortality in all Danish patients with incident ICD-10-defined AD from 2000 through 2011...
April 3, 2018: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/29658428/caregivers-perspectives-of-quality-of-life-of-people-with-young-and-late-onset-alzheimer-disease
#7
Nathália R S Kimura, Maria Alice T Baptista, Raquel L Santos, Maria da Gloria Portugal, Aud Johannenssen, Maria L Barca, Knut Engedal, Jerson Laks, José Pedro Simões, Valeska Marinho Rodrigues, Marcia C N Dourado
BACKGROUND: Quality of life (QoL) is a growing area of interest in dementia research. This study aims to investigate the caregivers' perspective about the QoL of people with young-onset Alzheimer disease (YOAD) and late-onset Alzheimer disease (LOAD). We also aim to investigate factors that might be associated to caregivers' perspective in YOAD and LOAD. METHODS: We included 110 people with Alzheimer disease (PwAD; 53 YOAD) and their primary caregivers. The PwAD completed assessments about their QoL and cognition...
March 2018: Journal of Geriatric Psychiatry and Neurology
https://www.readbyqxmd.com/read/29655397/team-composition-and-chronic-disease-management-within-primary-healthcare-practices-in-eastern-ontario-an-application-of-the-measuring-organizational-attributes-of-primary-health-care-survey
#8
Julia Lukewich, Dana S Edge, Elizabeth VanDenKerkhof, Tyler Williamson, Joan Tranmer
BACKGROUND: Various organizational-level attributes are being implemented in primary healthcare to improve healthcare delivery. There is a need to describe the distribution and nature of these attributes and explore differences across practices.AimThe aim of this study was to better understand organizational attributes of primary care teams, focusing specifically on team composition, nursing roles, and strategies that support chronic disease management. METHODS: We employed a cross-sectional survey design...
April 15, 2018: Primary Health Care Research & Development
https://www.readbyqxmd.com/read/29644989/the-palliative-care-in-dementia-context-health-professionals-point-of-view-about-advantages-and-resistances
#9
Sabina Zapponi, Maria Chiara Ascari, Erjona Feracaku, Silvia Masin, Paola Paglia, Roberta Petroccione, Ana Pinzaru, Chiara Foà, Giovanna Artioli, Leopoldo Sarli
BACKGROUND AND AIM: The 38/2010 law has expanded the provision of palliative care to patients with chronic-degenerative diseases. The ISTAT data show that 60% of the dying population is suffering from these diseases and could, according to the literature review, benefit particularly from such treatments. This study investigates the point of view of healthcare professionals, working in the context of dementia, regarding the knowledge and application of palliative care in the field of dementia...
March 26, 2018: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/29642716/thematic-analysis-of-blog-narratives-written-by-people-with-alzheimer-s-disease-and-other-dementias-and-care-partners
#10
Kristie Kannaley, Shreya Mehta, Brooks Yelton, Daniela B Friedman
Limited research takes a socio-biographical approach to study the experiences and perspectives of individuals affected by Alzheimer's disease and related dementias. The purpose of this study was to thematically analyze blog narratives written by people with Alzheimer's disease and related dementia and care partners in order to increase understanding of their experiences. Nineteen blogs written by people with Alzheimer's disease and related dementia and 44 blogs written by care partners were analyzed. The first two authors utilized line-by-line open coding to analyze five posts from each group for the development of a codebook...
January 1, 2018: Dementia
https://www.readbyqxmd.com/read/29629495/lewy-body-disease-clinical-and-pathological-overlap-syndrome-between-synucleinopathies-parkinson-disease-and-tauopathies-alzheimer-disease
#11
REVIEW
Clovis Foguem, Patrick Manckoundia
Lewy body disease (LBD) is a neurodegenerative disease resulting in dementia. It shares clinical and pathological features with Parkinson disease (PD), the most frequent synucleinopathy, Parkinson disease dementia (PDD), and Alzheimer disease (AD), a tauopathy. Even though the diagnostic criteria for these neurodegenerative diseases are clearly established, and recently revised for LBD, their precise clinical diagnosis is often difficult because LBD, PD, PDD, and AD share epidemiological, clinical, and pathological characteristics...
April 8, 2018: Current Neurology and Neuroscience Reports
https://www.readbyqxmd.com/read/29628039/-economic-impact-of-cognitive-impairment-and-dementia
#12
David Cantarero Prieto
Increased life expectancy has had a corresponding socioeconomic impact due to the ageing population and, among other issues, has increased the incidence of diseases related to cognitive impairment, such as dementia. These changes particularly affect the most developed countries. Any analysis of economic costs aiming to study patients with health problems related to cognitive impairment or dementia should consider the reality of the distinct phases of these disorders and should be conducted from the perspective of the payer, that is, the publicly-funded healthcare system...
June 2017: Revista Española de Geriatría y Gerontología
https://www.readbyqxmd.com/read/29623839/identifying-patterns-in-signs-and-symptoms-preceding-the-clinical-diagnosis-of-alzheimer-s-disease-retrospective-medical-record-review-study-and-a-nested-case-control-design
#13
Fidelia Bature, Dong Pang, Anthea Robinson, Norma Polson, Yannis Pappas, Barbara Guinn
OBJECTIVE: Evidence suggests that individuals with Alzheimer's disease (AD) are often diagnosed in the later stages of their disease with a poor prognosis. This study aimed to identify patterns in signs and symptoms preceding the clinical diagnosis of AD to suggest a predictive model for earlier diagnosis of the disease in the primary care. DESIGN: A retrospective medical record review; nested case control design. PARTICIPANTS: Participants included one hundred and nine patients from three general practice (GP) surgeries in Milton Keynes and Luton Clinical Commissioning groups (CCG) (37 cases with AD and 72 controls without AD)...
April 4, 2018: Current Alzheimer Research
https://www.readbyqxmd.com/read/29623103/linearized-and-kernelized-sparse-multitask-learning-for-predicting-cognitive-outcomes-in-alzheimer-s-disease
#14
Xiaoli Liu, Peng Cao, Jinzhu Yang, Dazhe Zhao
Alzheimer's disease (AD) has been not only the substantial financial burden to the health care system but also the emotional burden to patients and their families. Predicting cognitive performance of subjects from their magnetic resonance imaging (MRI) measures and identifying relevant imaging biomarkers are important research topics in the study of Alzheimer's disease. Recently, the multitask learning (MTL) methods with sparsity-inducing norm (e.g., ℓ 2,1 -norm) have been widely studied to select the discriminative feature subset from MRI features by incorporating inherent correlations among multiple clinical cognitive measures...
2018: Computational and Mathematical Methods in Medicine
https://www.readbyqxmd.com/read/29621480/identifying-dementia-cases-with-routinely-collected-health-data-a-systematic-review
#15
Tim Wilkinson, Amanda Ly, Christian Schnier, Kristiina Rannikmäe, Kathryn Bush, Carol Brayne, Terence J Quinn, Cathie L M Sudlow
INTRODUCTION: Prospective, population-based studies can be rich resources for dementia research. Follow-up in many such studies is through linkage to routinely collected, coded health-care data sets. We evaluated the accuracy of these data sets for dementia case identification. METHODS: We systematically reviewed the literature for studies comparing dementia coding in routinely collected data sets to any expert-led reference standard. We recorded study characteristics and two accuracy measures-positive predictive value (PPV) and sensitivity...
April 2, 2018: Alzheimer's & Dementia: the Journal of the Alzheimer's Association
https://www.readbyqxmd.com/read/29620941/cerebrovascular-%C3%AE-amyloid-deposition-and-associated-microhemorrhages-in-a-tg2576-alzheimer-mouse-model-are-reduced-with-a-dha-enriched-diet
#16
Justine Hur, Véronique Mateo, Nicolas Amalric, Mégane Babiak, Gilbert Béréziat, Claire Kanony-Truc, Thierry Clerc, Régis Blaise, Isabelle Limon
Cerebral amyloid angiopathy (CAA) is a major contributor to Alzheimer's disease (AD) pathogenesis. Like AD, CAA is often accompanied by marked inflammation, aggravating associated vasculopathies. No evidence-based prevention or treatment strategies are available. Here, we evaluate the possible beneficial effect of a diet enriched with docosahexaenoic acid (DHA), which is known to attenuate inflammation in CAA. Tg2576 mice, a transgenic model of AD/CAA, were fed a DHA-enriched diet starting at 2 mo of age and ending at 10, 14, or 18 mo of age...
April 5, 2018: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://www.readbyqxmd.com/read/29618598/routine-assessment-and-promotion-of-physical-activity-in-healthcare-settings-a-scientific-statement-from-the-american-heart-association
#17
REVIEW
Felipe Lobelo, Deborah Rohm Young, Robert Sallis, Michael D Garber, Sandra A Billinger, John Duperly, Adrian Hutber, Russell R Pate, Randal J Thomas, Michael E Widlansky, Michael V McConnell, Elizabeth A Joy
Physical inactivity is one of the most prevalent major health risk factors, with 8 in 10 US adults not meeting aerobic and muscle-strengthening guidelines, and is associated with a high burden of cardiovascular disease. Improving and maintaining recommended levels of physical activity leads to reductions in metabolic, hemodynamic, functional, body composition, and epigenetic risk factors for noncommunicable chronic diseases. Physical activity also has a significant role, in many cases comparable or superior to drug interventions, in the prevention and management of >40 conditions such as diabetes mellitus, cancer, cardiovascular disease, obesity, depression, Alzheimer disease, and arthritis...
April 4, 2018: Circulation
https://www.readbyqxmd.com/read/29616602/correlates-of-nursing-care-burden-among-institutionalized-patients-with-dementia
#18
Meng Sun, Brian J Mainland, Tisha J Ornstein, Gwen Li Sin, Nathan Herrmann
ABSTRACTBackground:The stress associated with care of patients with dementia has led to high nursing staff turnover. This study aims to explore patient factors that are related to nursing burden. METHODS: The present study examined nursing care burden related to 55 institutionalized dementia patients using the Modified Nursing Care Assessment Scale (M-NCAS). Cognition was assessed with the Severe Impairment Battery (SIB), activities of daily living (ADLs) were measured with the Alzheimer's Disease Functional Assessment of Change Scale (ADFACS), aggression was measured with the Aggressive Behavior Scale (ABS), and the Charlson Comorbidity Index (CCI) was used to assess medical comorbidity...
April 4, 2018: International Psychogeriatrics
https://www.readbyqxmd.com/read/29614680/novel-grn-mutations-in-alzheimer-s-disease-and-frontotemporal-lobar-degeneration
#19
Irene Piaceri, Daniele Imperiale, Enrico Ghidoni, Cristiana Atzori, Silvia Bagnoli, Camilla Ferrari, Silvana Ungari, Luca Ambrogio, Sandro Sorbi, Benedetta Nacmias
BACKGROUND: During the twentieth century, frontotemporal dementia (FTD) was often misdiagnosed, confused with Alzheimer's disease or psychiatric disorders, jeopardizing care and research. OBJECTIVE: To analyze the FTD genes in the DNA samples of patients belonging to families clinically classified as probable Alzheimer's disease (FAD) in the early 1990s and not carrying mutation in the three main genes linked to FAD (Presenilin 1, Presenilin 2, and Amyloid precursor protein)...
2018: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/29614643/caregiving-and-caregiver-burden-in-dementia-home-care-results-from-the-prospective-dementia-registry-prodem-of-the-austrian-alzheimer-society
#20
Gerhard Ransmayr, Philipp Hermann, Katharina Sallinger, Thomas Benke, Stephan Seiler, Peter Dal-Bianco, Josef Marksteiner, Michaela Defrancesco, Günter Sanin, Walter Struhal, Michael Guger, Milan Vosko, Karin Hagenauer, Riccarda Lehner, Andreas Futschik, Reinhold Schmidt
BACKGROUND: Comprehensive studies on caregiver burden (CB) of persons caring for dementia patients differ methodologically and show variable results. OBJECTIVE: Analysis of known and hypothesized factors of CB in home care of dementia patients. METHODS: Multicenter longitudinal study comprising 585 persons caring mostly for Alzheimer's disease patients (age median 77.25 years, Mini-Mental State Examination raw score median 23) using the Zarit Caregiver Burden interview (CBI)...
March 29, 2018: Journal of Alzheimer's Disease: JAD
keyword
keyword
105460
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"