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Olive leaf extract

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https://www.readbyqxmd.com/read/28881013/pencil-graphite-electrodes-for-improved-electrochemical-detection-of-oleuropein-by-the-combination-of-natural-deep-eutectic-solvents-and-graphene-oxide
#1
Federico J V Gomez, Adrian Spisso, María Fernanda Silva
A novel methodology is presented for the enhanced electrochemical detection of oleuropein in complex plant matrices by Graphene Oxide Pencil Grahite Electrode (GOPGE) in combination with a buffer modified with a Natural Deep Eutectic Solvent, containing 10% (v/v) of Lactic acid, Glucose and H2 O (LGH). The electrochemical behavior of oleuropein in the modified-working buffer was examined using differential pulse voltammetry. The combination of both modifications, NADES modified buffer and nanomaterial modified electrode, LGH-GOPGE, resulted on a signal enhancement of 5...
September 7, 2017: Electrophoresis
https://www.readbyqxmd.com/read/28859105/programmed-cell-death-in-acanthamoeba-castellanii-neff-induced-by-several-molecules-present-in-olive-leaf-extracts
#2
Ines Sifaoui, Atteneri López-Arencibia, Carmen Mª Martín-Navarro, María Reyes-Batlle, Carolina Wagner, Olfa Chiboub, Mondher Mejri, Basilio Valladares, Manef Abderrabba, José E Piñero, Jacob Lorenzo-Morales
Therapy against Acanthamoeba infections such as Granulomatous Amoebic Encephalitis (GAE) and Acanthamoeba Keratitis (AK), remains as an issue to be solved due to the existence of a cyst stage which is highly resistant to most chemical and physical agents. Recently, the activity of Olive Leaf Extracts (OLE) was demonstrated against Acanthamoeba species. However, the molecules involved in this activity were not identified and/or evaluated. Therefore, the aim of this study was to evaluate the activity of the main molecules which are present in OLE and secondly to study their mechanism of action in Acanthamoeba...
2017: PloS One
https://www.readbyqxmd.com/read/28808475/yacon-smallanthus-sonchifolius-leaf-extract-attenuates-hyperglycemia-and-skeletal-muscle-oxidative-stress-and-inflammation-in-diabetic-rats
#3
Klinsmann Carolo Dos Santos, Bianca Guerra Bueno, Luana Ferreira Pereira, Fabiane Valentini Francisqueti, Mariana Gobbo Braz, Lahis Fernandes Bincoleto, Lilian Xavier da Silva, Ana Lúcia A Ferreira, Ana Cláudia de Melo Stevanato Nakamune, C-Y Oliver Chen, Jeffrey B Blumberg, Camila Renata Corrêa
The effects of hydroethanolic extract of Yacon leaves (HEYL) on antioxidant, glycemic, and inflammatory biomarkers were tested in diabetic rats. Outcome parameters included glucose, insulin, interleukin-6 (IL-6), and hydrophilic antioxidant capacity (HAC) in serum and IL-6, HAC, malondialdehyde (MDA), superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) in soleus. The rats (10/group) were divided as follows: C, controls; C + Y, HEYL treated; DM, diabetic controls; and DM + Y, diabetic rats treated with HEYL...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28802847/structural-antioxidant-and-antimicrobial-activities-of-polysaccharides-extracted-from-olive-leaves
#4
Ibtihel Khemakhem, Ola Abdelhedi, Ines Trigui, Mohamed Ali Ayadi, Mohamed Bouaziz
In the present study, hot-water extraction procedure was used to recover polysaccharides from olive leaves. Primary structural characteristics were determined by nuclear magnetic resonance spectroscopy ((1)H NMR and (13)C NMR), Fourier Transform-Infrared spectroscopy (FT-IR) and X-ray diffractometry analysis. Emulsifying capacity, Zeta (ζ) potential and differential scanning calorimetric (DSC) of olive leaf polysaccharides (OLP) were investigated. Antioxidant and antimicrobial activities were then examined...
August 9, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28740293/ultrasound-assisted-extraction-process-of-phenolic-antioxidants-from-olive-leaves-a-nutraceutical-study-using-rsm-and-lc-esi-dad-ms
#5
Habib Shirzad, Vahid Niknam, Mehdi Taheri, Hassan Ebrahimzadeh
In recent years, there has been an ever growing interest in finding new natural sources of food antioxidants. As a main fruit crop, olive is also valued due to its phenolic-containing leaves. Mathematically based optimization methods are used as powerful tools to extract different antioxidant compounds. The present study is aimed to provide an efficient extraction method for total phenol content (TPC), total flavonoid content (TFC) and antioxidant ability (DPPH scavenging assay and FRAP). The effects of ultrasonic temperature (35-65 °C), ultrasonic time (5-15 min), and ethanol to water ratio (Et: W) (25-75%) were evaluated...
July 2017: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/28731213/immunomodulatory-properties-of-olea-europaea-leaf-extract-in-intestinal-inflammation
#6
Teresa Vezza, Francesca Algieri, Alba Rodríguez-Nogales, José Garrido-Mesa, M Pilar Utrilla, Nassima Talhaoui, Ana María Gómez-Caravaca, Antonio Segura-Carretero, M Elena Rodríguez-Cabezas, Giovanni Monteleone, Julio Gálvez
SCOPE: Extracts from olive (Olea europaea) leaves are used in Mediterranean traditional medicine as anti-inflammatory. They contain antioxidant phenolic compounds, like oleuropeoside, which could be interesting for the treatment of inflammatory conditions associated with oxidative stress in humans, including inflammatory bowel disease. METHODS AND RESULTS: The anti-inflammatory effects of olive leaf extract (0.5-25 mg/kg) were studied in two mice models of colitis (DSS and DNBS)...
July 21, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28700722/anti-inflammatory-properties-of-extracts-from-chimonanthus-nitens-oliv-leaf
#7
Qi Sun, Jiajin Zhu, Feiwei Cao, Fengjia Chen
Chimonanthus nitens Oliv. (CN) is a species in the family Calycanthaceae. Its leaf is widely used to make traditional herbal tea in southern China and has a wide range of therapeutic effects. The profile of the ethanol extracts from CN leaves was identified by UPLC-QTOF-MS/MS. Forty seven compounds were determined including organic acids, phenolic acids and derivatives, flavonoids, coumarins, fatty acids and other compounds. The effect of the CN extracts on the inflammatory damage in zebrafish and in RAW 264...
2017: PloS One
https://www.readbyqxmd.com/read/28672807/solvent-free-microwave-assisted-extraction-of-polyphenols-from-olive-tree-leaves-antioxidant-and-antimicrobial-properties
#8
Selin Şahin, Ruya Samli, Ayşe Seher Birteksöz Tan, Francisco J Barba, Farid Chemat, Giancarlo Cravotto, José M Lorenzo
Response surface methodology (RSM) and artificial neural networks (ANN) were evaluated and compared in order to decide which method was the most appropriate to predict and optimize total phenolic content (TPC) and oleuropein yields in olive tree leaf (Oleaeuropaea) extracts, obtained after solvent-free microwave-assisted extraction (SFMAE). The SFMAE processing conditions were: microwave irradiation power 250-350 W, extraction time 2-3 min, and the amount of sample 5-10 g. Furthermore, the antioxidant and antimicrobial activities of the olive leaf extracts, obtained under optimal extraction conditions, were assessed by several in vitro assays...
June 24, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28637415/study-on-adsorption-and-sustained-release-of-eucommia-ulmoides-oliv-leaf-extracts-on-activated-carbon
#9
Sheng Zhang, Xiang-Zhou Li, Zhao-Yan Zeng
Activated carbon (AC) was employed in this study as the sustained release carrier and its capability for adsorption and sustained release of Eucommia ulmoides Oliv. leaf extracts was systematically investigated. Acid or alkali modified AC was assessed for its ability to adsorb and sustain release of Eucommia ulmoides Oliv. leaf extracts according to a variety of adsorption/release rate and composition. Results demonstrated that the adsorption rate for the differently modified AC reached above 80 %, the adsorption of Eucommia ulmoides Oliv...
June 21, 2017: Current Drug Delivery
https://www.readbyqxmd.com/read/28559631/effect-of-olive-leaf-extract-rich-in-oleuropein-on-the-quality-of-virgin-olive-oil
#10
Selin Şahin, Ezgi Sayım, Mehmet Bilgin
Effect of olive leaf extract rich in oleuropein on the quality of virgin olive oil was investigated. After extracting the dried and ground olive leaves with the assistance of homogenizer, the dried extract was partially dissolved into the oil to increase the oxidative stability of the oil. A face central composite design through response surface methodology was used to investigate the effects of enrichment conditions (extract content, time and mixing speed) on the responses, total phenolic content and oleuropein concentration of the enriched olive oil...
May 2017: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/28551177/new-semi-synthetic-analogs-of-oleuropein-show-improved-anticancer-activity-in%C3%A2-vitro-and-in%C3%A2-vivo
#11
Pinelopi Samara, Nikoleta Christoforidou, Christelle Lemus, Aikaterini Argyropoulou, Kyriaki Ioannou, Konstantina Vougogiannopoulou, Nektarios Aligiannis, Efthimios Paronis, Nicolas Gaboriaud-Kolar, Ourania Tsitsilonis, Alexios-Leandros Skaltsounis
Oleuropein is a glucosylated seco-iridoid present in olive fruits and leaves. Due to its broad spectrum of biological activities, including anticancer properties, oleuropein has attracted scientific attention for the past 20 years. The promising antiproliferative activity of an olive leaf extract enriched in oleuropein against a series of human cancer cell lines, prompted us to proceed with the semi-synthesis of 51 analogs of oleuropein. Following their initial screening against the estrogen receptor negative breast cancer cell line SKBR3, 7 analogs were shown to display significant cytotoxicity and were further tested against 6 additional solid tumor-derived and leukemic cell lines...
September 8, 2017: European Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/28513570/a-study-of-the-protective-properties-of-iraqi-olive-leaves-against-oxidation-and-pathogenic-bacteria-in-food-applications
#12
Ammar B Altemimi
There is an ancient and prodigious history of olive trees because of their nutritional, medicinal, and traditional uses. Intensive studies have been conducted on olive leaves because they have many positive and beneficial effects for human health. In this study, different solvents were used to examine the olive leaves for their antioxidant and antimicrobial activities and their possible food applications. The obtained results showed that the amounts of phenolic compounds of the olive leaf were 190.44 ± 0.50, 173 ± 1...
May 17, 2017: Antioxidants (Basel, Switzerland)
https://www.readbyqxmd.com/read/28503711/bioactivity-improvement-of-olea-europaea-leaf-extract-biotransformed-by-wickerhamomyces-anomalus-enzymes
#13
Rosa Palmeri, Cristina Restuccia, Julieta Ines Monteleone, Elisa Sperlinga, Laura Siracusa, Mauro Serafini, Alberto Finamore, Giovanni Spagna
Olive leaves represent a quantitatively significant by-product of agroindustry. They are rich in phenols, mainly oleuropein, which can be hydrolyzed into several bioactive compounds, including hydroxytyrosol. In this study, water extract from olive leaves 'Biancolilla' was analyzed for polyphenol profile, DPPH (2,2-diphenyl-1-picrylhydrazyl) radical scavenging activity and protective effect on differentiated Caco-2 cells. The efficacy of two enzymatic treatments in promoting the release of bioactive phenols was investigated: a) enzymatic extract from Wickerhamomyces anomalus, characterized by β-glucosidase and esterase activities; b) commercial β-glucosidase...
June 2017: Plant Foods for Human Nutrition
https://www.readbyqxmd.com/read/28479728/in-vitro-toxicity-and-genotoxic-activity-of-aqueous-leaf-extracts-from-four-varieties-of-olea-europea-l
#14
Luc Verschaeve, Hayet Edziri, Roel Anthonissen, Dalenda Boujnah, Fethia Skhiri, Hechmi Chehab, Mahjoub Aouni, Maha Mastouri
AIM: Despite its therapeutic value almost nothing is known about potential adverse health effects of Olea europea L. We therefore investigated the in vitro toxicity and genotoxicity of leaf extracts of this plant. MATERIAL AND METHODS: Extracts from olive tree leaves were obtained from four different regions in Tunisia. We investigated the in vitro toxicity, genotoxicity and antigenotoxicity of their aqueous extracts using the neutral red (NR) uptake, Vitotox and alkaline comet assays...
January 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/28476307/isolation-of-organic-compounds-with-high-added-values-from-agro-industrial-solid-wastes
#15
Dimitris P Zagklis, Christakis A Paraskeva
Phenols are organic compounds with high antioxidant activity. Occurring mainly in plants, where they act as pigments or even as part of defense mechanisms against insects and herbivores. Given the positive impact on on human health, their isolation and purification from agricultural products is of particular interest for the production of nutritional, pharmaceutical and cosmetics supplements. In our study different materials rich in phenolic compounds were used, in order to separate the phenolic content and maximum condensation using physicochemical methods such as solvent extraction, filtration through membranes, adsorption/desorption on resins and vacuum distillation...
May 2, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28463797/olive-olea-europaea-leaf-methanolic-extract-prevents-hcl-ethanol-induced-gastritis-in-rats-by-attenuating-inflammation-and-augmenting-antioxidant-enzyme-activities
#16
Saleh Al-Quraishy, Mohamed S Othman, Mohamed A Dkhil, Ahmed Esmat Abdel Moneim
Gastritis is preponderantly characterized by inflammation of the lining epithelial layer and the chronic gastritis is considered as a pre-cancer lesion. For many centuries olive (Olea europaea) leaf has been used for its putative health potential, nonetheless, to date, the gastroprotective effects of olive leaves have not been studied yet. Hence, in this study we investigated whether olive leaf extract (OLE) could protect gastric mucosa against HCl/ethanol-induced gastric mucosal damage in rats. Hcl/ethanol administration caused significant damage to the gastric mucosa, as confirmed by gastric ulcer index and histological evaluation...
July 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28461019/retracted-polar-and-apolar-extra-virgin-olive-oil-and-leaf-extracts-as-a-promising-anti-inflammatory-natural-treatment-for-osteoarthritis
#17
Houda Nsir, Marta Anna Szychlinska, Venera Cardile, Adriana Carol Eleonora Graziano, Rosanna Avola, Hanen Esafi, Alessandra Bendini, Mokhtar Zarouk, Carla Loreto, Venerando Rapisarda, Paola Castrogiovanni, Giuseppe Musumeci
This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). This article has been retracted at the request of the Authors. An anonymous reader made the authors aware of potential errors in the presentation and the experimental design for the Western blot data in Figure 3. Upon thorough investigation the authors concluded that in fact, in addition to an honest error (wrong image selected for inclusion into the article), the experimental design was not state-of-the-art in that the loading controls were run on parallel gels rather than on the gels to be probed for iNOS and collagen II...
May 2017: Acta Histochemica
https://www.readbyqxmd.com/read/28452059/arrhenius-equation-modeling-for-the-shelf-life-prediction-of-tomato-paste-containing-a-natural-preservative
#18
Seid Mahdi Jafari, Mohammad Ganje, Danial Dehnad, Vahid Ghanbari, Javad Hajitabar
BACKGROUND: In this study, shelf life of tomato paste with microencapsulated olive leaf extract was compared with samples containing commercial preservatives by accelerated shelf life testing. Based on previous studies, it has been shown that olive leaf extract as a rich source of phenolic compounds can have antimicrobial properties; so we proposed application of its encapsulated form to improve the storage stability of tomato paste. RESULTS: Regarding Total Soluble Solids, control and the sample containing 1000 ppm sodium benzoate represented the lowest (1...
April 28, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28419967/olea-europaea-leaf-extract-and-bevacizumab-synergistically-exhibit-beneficial-efficacy-upon-human-glioblastoma-cancer-stem-cells-through-reducing-angiogenesis-and-invasion-in-vitro
#19
Gulcin Tezcan, Mevlut Ozgur Taskapilioglu, Berrin Tunca, Ahmet Bekar, Hilal Demirci, Hasan Kocaeli, Secil Ak Aksoy, Unal Egeli, Gulsah Cecener, Sahsine Tolunay
Patients with glioblastoma multiforme (GBM) that are cancer stem-cell-positive (GSC [+]) essentially cannot benefit from anti-angiogenic or anti-invasive therapy. In the present study, the potential anti-angiogenic and anti-invasive effects of Olea europaea (olive) leaf extract (OLE) were tested using GSC (+) tumours. OLE (2mg/mL) caused a significant reduction in tumour weight, vascularisation, invasiveness and migration (p=0.0001, p<0.001, p=0.004; respectively) that was associated with reducing the expression of VEGFA, MMP-2 and MMP-9...
June 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28382717/the-origin-of-aliphatic-hydrocarbons-in-olive-oil
#20
Manuel Pineda, María Rojas, Gregorio Gálvez-Valdivieso, Miguel Aguilar
BACKGROUND: There are many substances that can interfere with olive oil quality. Some of them are well characterized, but many others have an unknown origin. Saturated hydrocarbons make an extraordinary complex family of numerous molecules, some of them present naturally in vegetable oils. When major natural saturated hydrocarbons are analyzed by standard chromatographic methods, this complex mixture of saturated hydrocarbons appears as a hump in the chromatogram and is commonly named as unresolved complex mixture (UCM) whose origin remains unknown...
April 6, 2017: Journal of the Science of Food and Agriculture
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