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asthma and pollution

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https://www.readbyqxmd.com/read/29345235/news-on-climate-change-air-pollution-and-allergic-trigger-factors-of-asthma
#1
REVIEW
M D Amato, L Cecchi, I Annesi-Maesano, G D Amato
The rising frequency of obstructive respiratory diseases,in particular allergic asthma, observed over the last years, can be partially explained by changes occurring in the environment, with increasing presence in atmosphere of chemical (particulate matter and gaseous components such as nitrogen dioxide and ozone) and biologic (aeroallergens) trigger factors. Aeroallergens are able to stimulate, in allergic subjects, the airways' sensitization, inducing symptoms of bronchial asthma. Over the last 50 years, global earth's temperature has markedly risen likely because of growing emission of anthropogenic greenhouse gas concentrations...
January 17, 2018: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/29325306/-a-retrospective-study-of-the-inducing-factors-and-clinical-characteristics-of-patients-hospitalized-for-asthma-exacerbation-in-china-in-2013-2014
#2
B Xing, J T Lin, H P Tang, L Yang, Y D Yuan, Y H Gu, P Chen, X J Liu, J Zhang, H G Liu, C Z Wang, W Zhou, D J Sun, Y Q Chen, Z C Chen, M Huang, Q C Lin, C P Hu, X H Yang, J M Huo, X W Ye, X Zhou, P Jiang, W Zhang, Y J Huang, L M Dai, R Y Liu, S X Cai, J Y Xu, J Y Zhou
Objective: To study the inducing factors and clinical characteristics of patients hospitalized for asthma exacerbation in China. Methods: Patients hospitalized for asthma exacerbation at 29 hospitals in China were retrospectively recruited during 2013-2014. Results: Clinical data of 3 240 asthmatic patients were collected and analyzed including 1 369(42.3%) males and 1 871(57.7%) females. The patients hospitalized for asthma exacerbation counted for 2.95% (6 375/215 955) of all patients hospitalized during the same period...
January 1, 2018: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
https://www.readbyqxmd.com/read/29324378/impact-evaluation-of-environmental-factors-on-respiratory-function-of-asthma-patients-living-in-urban-territory
#3
Lyudmila V Veremchuk, Konstantinos Tsarouhas, Tatyana I Vitkina, Elena E Mineeva, Tatyana A Gvozdenko, Marina V Antonyuk, Valeri N Rakitskii, Karolina A Sidletskaya, Aristidis M Tsatsakis, Kirill S Golokhvast
BACKGROUND: Environmental pollution, local climatic conditions and their association with the prevalence and exacerbation of asthma are topics of intense current medical investigation. MATERIALS AND METHODS: Air pollution in the area of Vladivostock was estimated both by the index of emission volumes of "air gaseous components" (nitrogen oxide and nitrogen dioxide, formaldehyde, hydrogen sulfide, carbon monoxide) in urban atmosphere and by mass spectrometric analysis of precipitates in snow samples...
January 8, 2018: Environmental Pollution
https://www.readbyqxmd.com/read/29320438/modeling-unobserved-heterogeneity-in-susceptibility-to-ambient-benzo-a-pyrene-concentration-among-children-with-allergic-asthma-using-an-unsupervised-learning-algorithm
#4
Daniel Fernández, Radim J Sram, Miroslav Dostal, Anna Pastorkova, Hans Gmuender, Hyunok Choi
Current studies of gene × air pollution interaction typically seek to identify unknown heritability of common complex illnesses arising from variability in the host's susceptibility to environmental pollutants of interest. Accordingly, a single component generalized linear models are often used to model the risk posed by an environmental exposure variable of interest in relation to a priori determined DNA variants. However, reducing the phenotypic heterogeneity may further optimize such approach, primarily represented by the modeled DNA variants...
January 10, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29317916/exposure-to-no2-co-and-pm2-5-is-linked-to-regional-dna-methylation-differences-in-asthma
#5
Mary Prunicki, Laurel Stell, Deendayal Dinakarpandian, Mariangels de Planell-Saguer, Richard W Lucas, S Katharine Hammond, John R Balmes, Xiaoying Zhou, Tara Paglino, Chiara Sabatti, Rachel L Miller, Kari C Nadeau
Background: DNA methylation of CpG sites on genetic loci has been linked to increased risk of asthma in children exposed to elevated ambient air pollutants (AAPs). Further identification of specific CpG sites and the pollutants that are associated with methylation of these CpG sites in immune cells could impact our understanding of asthma pathophysiology. In this study, we sought to identify some CpG sites in specific genes that could be associated with asthma regulation (Foxp3 and IL10) and to identify the different AAPs for which exposure prior to the blood draw is linked to methylation levels at these sites...
2018: Clinical Epigenetics
https://www.readbyqxmd.com/read/29314275/an-approach-to-the-asthma-protective-farm-effect-by-geocoding-good-farms-and-better-farms
#6
Susanne E K Müller-Rompa, Iana Markevych, Alexander J Hose, Georg Loss, Inge M Wouters, Jon Genuneit, Charlotte Braun-Fahrländer, Elisabeth Horak, Andrzej Boznanski, Dick Heederik, Erika von Mutius, Joachim Heinrich, Markus J Ege
BACKGROUND: The highly consistent association of growing up on a farm with a reduced asthma risk has so far been attributed to direct farm exposure. In contrast, geographical determinants of the larger environment have never been assessed. In this study, the effects of proximity to farms and environmental variables in relation to the residential address on asthma and atopy were assessed. METHODS: Addresses of 2,265 children of the Bavarian arm of the GABRIELA-study were converted into geocodes...
January 4, 2018: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/29313309/air-pollution-and-allergic-airway-diseases-social-determinantsand-sustainability-in-the-control-and-prevention
#7
REVIEW
H Paramesh
Air pollution, global warming and climate change are the major contributing factors in causing the increase prevalence of allergic airway diseases like asthma and allergic rhinitis and they will be the defining issues for health system in the twenty-first century. Asthma is an early onset non-communicable environmental disease with global epidemic and contributes a greatest psycho socio economic burden. Nearly 8 million global deaths are from air pollution. Over one billion population are the sufferers during 2015 and will increase to 4 billion by 2050...
January 9, 2018: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/29310758/school-environmental-intervention-programs
#8
Perdita Permaul, Wanda Phipatanakul
Exposure to indoor allergens and pollutants plays a significant part in the development of asthma and its associated morbidity. Inner-city children with asthma are disproportionately affected by these exposures with increased asthma morbidity. Although years of previous research have linked exposures in the urban home environment with significant childhood asthma disease, many of these allergens are also present in inner-city school environments. Therefore, evaluation of the school environment of patients with asthma is also essential...
January 2018: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29300211/air-pollution-in-india-and-related-adverse-respiratory-health-effects-past-present-and-future-directions
#9
Gopi C Khilnani, Pawan Tiwari
PURPOSE OF REVIEW: The review describes current status of air pollution in India, summarizes recent research on adverse health effects of ambient and household air pollution, and outlines the ongoing efforts and future actions required to improve air quality and reduce morbidity and mortality because of air pollution in India. RECENT FINDINGS: Global burden of disease data analysis reveals more than one million premature deaths attributable to ambient air pollution in 2015 in India...
January 2, 2018: Current Opinion in Pulmonary Medicine
https://www.readbyqxmd.com/read/29291522/aqueous-and-organic-extract-of-pm2-5-collected-in-different-seasons-and-cities-of-japan-differently-affect-respiratory-and-immune-systems
#10
Pratiti Home Chowdhury, Hitoshi Okano, Akiko Honda, Hitomi Kudou, Gaku Kitamura, Sho Ito, Kayo Ueda, Hirohisa Takano
Particulate matter with diameters <2.5 μm (i.e., PM2.5) has multiple natural and anthropological sources. The association between PM2.5 and the exacerbation of respiratory allergy and asthma has been well studied, but the components of PM2.5 that are responsible for allergies have not yet been determined. Here, we elucidated the effects of aqueous and organic extract of PM2.5 collected during four seasons in November 2014-December 2015 in two cities (Kawasaki, an industrial area and Fukuoka, an urban area affected by transboundary pollution matter) of Japan on respiratory health...
December 28, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/29289783/air-pollutants-and-asthma-patient-visits-indication-of-source-influence
#11
Huibin Guo, Sijing Huang, Minxuan Chen
BACKGROUND: Sources of air pollutants are significant factors for adverse health effect. Few current studies explored the linking of sources influence and ambient pollutants to asthma patient visits in Shanghai, China. OBJECTIVES: This study explored the associations between short-term exposures to ambient pollutants and asthma morbidity with terrestrial and marine source influence in Shanghai. METHODS: Generalized additive model (GAM) was used to explore the association of daily patient visits and ambient pollutants...
December 28, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29278810/asthma-prevalence-and-school-related-hazardous-air-pollutants-in-the-us-m%C3%A3-xico-border-area
#12
Genny Carrillo, Maria J Perez Patron, Natalie Johnson, Yan Zhong, Rose Lucio, Xiaohui Xu
BACKGROUND: Asthma is the most common chronic disease in children and has been linked to high levels of ambient air pollution and certain hazardous air pollutants (HAPs). Outdoor pollutants such as benzene, released by car emissions, and organic chemicals found in diesel exhaust, as well as particles and irritant gases, including nitrogen dioxide (NO2), sulfur dioxide (SO2), and ozone (O3), contribute to an increased prevalence of respiratory diseases such as asthma. OBJECTIVES: The objectives of this study were to: 1) conduct a screening survey to identify high risk for asthma among school-age children in Hidalgo County, and, 2) study the potential health impact of school-related exposure to HAPs pertaining to asthma risk...
December 23, 2017: Environmental Research
https://www.readbyqxmd.com/read/29259031/fine-particulate-pollution-and-asthma-exacerbations
#13
Naïm Bouazza, Frantz Foissac, Saik Urien, Romain Guedj, Ricardo Carbajal, Jean-Marc Tréluyer, Hélène Chappuy
OBJECTIVE: As the results from epidemiological studies about the impact of outdoor air pollution on asthma in children are heterogeneous, our objective was to investigate the association between asthma exacerbation in children and exposure to air pollutants. METHODS: A database of 1 264 585 paediatric visits during the 2010-2015 period to the emergency rooms from 20 emergency departments (EDs) of 'Assistance Publique Hôpitaux de Paris (APHP)', the largest hospital group in Europe, was used...
December 19, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/29243937/long-term-coarse-pm-exposure-is-associated-with-asthma-among-children-in-medicaid
#14
Corinne A Keet, Joshua P Keller, Roger D Peng
RATIONALE: Short and long-term fine particulate matter (PM2.5) pollution is associated with asthma development and morbidity, but there is little data on the effects of long-term exposure to coarse PM (PM10-2.5) on respiratory health. OBJECTIVES: To understand the relationship between long-term fine and coarse PM exposure and asthma prevalence and morbidity among children. METHODS: A semi-parametric regression model that incorporated PM2.5 and PM10 monitor data and geographic characteristics was developed to predict two-year average PM2...
December 15, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/29238442/reducing-greenhouse-gas-emissions-and-improving-air-quality-two-global-challenges
#15
REVIEW
Larry E Erickson
There are many good reasons to promote sustainable development and reduce greenhouse gas emissions and other combustion emissions. The air quality in many urban environments is causing many premature deaths because of asthma, cardiovascular disease, chronic obstructive pulmonary disease, lung cancer, and dementia associated with combustion emissions. The global social cost of air pollution is at least $3 trillion/year; particulates, nitrogen oxides and ozone associated with combustion emissions are very costly pollutants...
July 2017: Environmental Progress & Sustainable Energy
https://www.readbyqxmd.com/read/29229079/city-housing-atmospheric-pollutant-impact-on-emergency-visit-for-asthma-a-classification-and-regression-tree-approach
#16
Julie Mazenq, Jean-Christophe Dubus, Jean Gaudart, Denis Charpin, Gilles Viudes, Guilhem Noel
INTRODUCTION: Particulate matter, nitrogen dioxide (NO2) and ozone are recognized as the three pollutants that most significantly affect human health. Asthma is a multifactorial disease. However, the place of residence has rarely been investigated. We compared the impact of air pollution, measured near patients' homes, on emergency department (ED) visits for asthma or trauma (controls) within the Provence-Alpes-Côte-d'Azur region. METHODS: Variables were selected using classification and regression trees on asthmatic and control population, 3-99 years, visiting ED from January 1 to December 31, 2013...
November 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/29227721/chinese-guidelines-for-childhood-asthma-2016-major-updates-recommendations-and-key-regional-data
#17
Jianguo Hong, Yixiao Bao, Aihuan Chen, Changchong Li, Li Xiang, Chuanhe Liu, Zhimin Chen, Deyu Zhao, Zhou Fu, Yunxiao Shang
OBJECTIVE: With increased industrialization and urbanization in China, pediatric asthma is becoming more prevalent. Despite a growing body of evidence, there remains a significant unmet need for adequate management of childhood asthma. The Subspecialty Group of Respiratory Diseases of the Society of Pediatrics, the Chinese Medical Association, and the editorial board of the Chinese Journal of Pediatrics have recently updated the "Guidelines for diagnosis and optimal management of asthma in children," first published in 2008...
December 11, 2017: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/29220800/exposure-to-traffic-related-air-pollution-and-the-composition-of-the-gut-microbiota-in-overweight-and-obese-adolescents
#18
Tanya L Alderete, Roshonda B Jones, Zhanghua Chen, Jeniffer S Kim, Rima Habre, Frederick Lurmann, Frank D Gilliland, Michael I Goran
BACKGROUND: Traffic-related air pollution (TRAP) exposure has been linked to type 2 diabetes and metabolic dysfunction in humans. Animal studies suggest that air pollutants may alter the composition of the gut microbiota, which may negatively impact metabolic health through changes in the composition and/or function of the gut microbiome. OBJECTIVES: The primary aim of this study was to determine whether elevated TRAP exposure was correlated with gut bacterial taxa in overweight and obese adolescents from the Meta-AIR (Metabolic and Asthma Incidence Research) study...
December 5, 2017: Environmental Research
https://www.readbyqxmd.com/read/29211546/association-of-outdoor-air-pollution-with-the-prevalence-of-asthma-in-children-of-latin-america-and-the-caribbean-a-systematic-review-and-meta-analysis
#19
Pablo Orellano, Nancy Quaranta, Julieta Reynoso, Brenda Balbi, Julia Vasquez
OBJECTIVE: This study aimed to evaluate the association between asthma prevalence and outdoor air pollution in children in Latin America and the Caribbean. DATA SOURCES: We searched studies in global and regional databases: PubMed, Scopus, LILACS and SciELO. STUDY SELECTION: Articles following a cross-sectional design, studying children from 0 to 18 years old, and comparing the prevalence of asthma in two or more areas of LAC countries with different air pollution levels were included...
December 6, 2017: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/29210519/air-pollutants-may-be-environmental-risk-factors-in-chronic-rhinosinusitis-disease-progression
#20
Leila J Mady, Hannah L Schwarzbach, John A Moore, Robert M Boudreau, Thomas J Willson, Stella E Lee
BACKGROUND: Little is known about the role of environmental exposures in the pathophysiology of chronic rhinosinusitis (CRS). In this study, we measured the impact of air pollutants (particulate matter 2.5 [PM2.5 ] and black carbon [BC]) on CRS with nasal polyposis (CRSwNP) and CRS without nasal polyposis (CRSsNP). METHODS: Spatial modeling from pollutant monitoring sites was used to estimate exposures surrounding residences for patients meeting inclusion criteria (total patients, n = 234; CRSsNP, n = 96; CRSwNP, n = 138)...
December 6, 2017: International Forum of Allergy & Rhinology
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